1,768 results match your criteria Microsporidiosis


Prevalence and genotypes of Enterocytozoon bieneusi in pigs in southern China.

Infect Genet Evol 2018 Sep 13;66:52-56. Epub 2018 Sep 13.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China; College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin Province 130118, PR China. Electronic address:

Enterocytozoon bieneusi is one of the most important causative agents of microsporidiosis, causing diarrhoea the symptoms of enteric disease in humans and animals. Although there is some information on the prevalence and genotypes of E. bieneusi in China, there is still a lack of data in pigs in southern China. Read More

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September 2018

The Potential Role of Synanthropic Rodents and Flies in the Transmission of Enterocytozoon bieneusi on a Dairy Cattle farm in China.

J Eukaryot Microbiol 2018 Sep 6. Epub 2018 Sep 6.

College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan, 450002, China.

Enterocytozoon bieneusi causes microsporidiosis, a condition with complex epidemiology involving both direct and indirect transmission routes. To assess the potential role of synanthropic rodents and flies in the transmission of this pathogen, a total of 277 cattle fecal samples, 199 synanthropic rodents, and 50 batches of 20 flies were collected from a cattle farm. These samples were screened for the presence of E. Read More

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September 2018
3.22 Impact Factor

Molecular characterization of methionine aminopeptidase 2 () gene and evaluation of anti-microsporidian activity of Fumagilin-B in silkworm .

3 Biotech 2018 Sep 24;8(9):386. Epub 2018 Aug 24.

Genomics Division, Seribiotech Research Laboratory, Carmelaram-Post, Kodathi, Bangalore, 560035 India.

is a spore-forming parasite causing microsporidiosis in silkworm . Methionine aminopeptidase 2 (), an essential gene of , is a target for the anti-microsporidian drug Fumagillin, an antibiotic derived from . In this study, a 1077 bp full-length cDNA of the gene of was cloned and characterized. Read More

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September 2018
2 Reads

Punctate epithelial keratoconjunctivitis: A microsporidial infestation.

Indian J Ophthalmol 2018 09;66(9):1327-1328

Jhaveri Microbiology Center, LV Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.

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September 2018
0.93 Impact Factor

Enterocytozoon bieneusi genotypes in people with gastrointestinal disorders in Queensland and Western Australia.

Infect Genet Evol 2018 Aug 18;65:293-299. Epub 2018 Aug 18.

Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

Enterocytozoon bieneusi is the commonest pathogenic microsporidian found in humans and animals in many countries, but there is scant information on this pathogen in Australia. Here, we conducted the first molecular epidemiological investigation of E. bieneusi in humans with gastrointestinal disorders in Queensland and Western Australia. Read More

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August 2018
2 Reads

Differences in the intensity of infection caused by Encephalitozoon cuniculi genotype II and III - Comparison using quantitative real-time PCR.

Exp Parasitol 2018 Sep 31;192:93-97. Epub 2018 Jul 31.

Institute of Parasitology, Biology Centre, Czech Academy of Science, České Budějovice, Czech Republic; Faculty of Agriculture, University of South Bohemia in České Budějovice, České Budějovice, Czech Republic.

Microsporidia are a group of obligate intracellular eukaryotic parasites, which are able to infect a wide range of animals, including humans. Four genotypes of Encephalitozoon cuniculi have been found to date. The different courses of microsporidiosis described in humans, which are dependent on immunological status of the host and genotype of E. Read More

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September 2018
1 Read

Respiratory microsporidiosis caused by Enterocytozoon bieneusi in a HIV-negative hematopoietic stem cell transplant recipient.

Int J Infect Dis 2018 Jul 28. Epub 2018 Jul 28.

Department of Biology and Medical Parasitology, Wroclaw Medical University, Wroclaw, Poland.

A 23 year-old, HIV-negative women who underwent hematopoietic stem cell transplantation was admitted to the hospital with respiratory failure and symptoms of bronchiolitis obliterans. The chest CT scan revealed diffuse ground glass opacification and fibrous plugs. Due to worsening respiratory failure despite treatment, ventilation through tracheostomy tube was conducted. Read More

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July 2018
2 Reads

Molecular characterization and new genotypes of Enterocytozoon bieneusi in minks (Neovison vison) in China.

Parasite 2018 20;25:34. Epub 2018 Jul 20.

Jilin Inspection and Quarantine Technology Center, Changchun, Jilin Province 130062, PR China - College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin Province 130118, PR China.

Microsporidiosis is an emerging and opportunistic disease, and Enterocytozoon bieneusi is the main cause of this disease in humans. Little information is available on prevalence and genotyping of E. bieneusi in minks. Read More

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July 2018
5 Reads

in Minks () in Northern China: A Public Health Concern.

Front Microbiol 2018 12;9:1221. Epub 2018 Jun 12.

Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China.

is the most important causative agent of microsporidiosis and can infect almost all vertebrate and invertebrate hosts, including minks (). In the present study, a total of 298 feces samples (including 79 from Heilongjiang province, 31 from Hebei province, 67 from Jilin province, 90 from Liaoning province, and 31 from Shandong province, Northern China) were examined by nested PCR amplification of the internal transcribed spacer (ITS) region of the rRNA gene. The overall prevalence of in minks was 10. Read More

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June 2018
6 Reads

Histopathological, ultrastructural and molecular phylogenetic analysis of a novel microsporidium in a loggerhead sea turtle Caretta caretta.

Dis Aquat Organ 2018 06;129(1):31-39

Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE C1A 4P3, Canada.

Microsporidial spores were identified in the musculature of a loggerhead sea turtle Caretta caretta found dead on the shore in New Brunswick, Canada. Gastroenteritis was diagnosed on gross postmortem examination, with no gross abnormalities detected in the skeletal muscle. Histologically, the microsporidial spores were associated with inflammation and muscular necrosis and measured 1. Read More

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June 2018
6 Reads

Encephalitozoon cuniculi infection in Barbary striped grass mice (Lemniscomys barbarus).

Schweiz Arch Tierheilkd 2018 Jun;160(6):394-400

Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich.

Introduction: Encephalitozoon cuniculi is an obligate intracellular microsporidian parasite that commonly induces subclinical infections in rabbits, but occurs also in a range of other species, including various rodents, carnivores, humans and birds. The present report describes encephalitozoonosis in a group of captive Barbary striped grass mice (Lemniscomys barbarus) in a zoo collection. The aetiology was confirmed by immunohistochemistry and PCR with subsequent sequencing. Read More

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SYSTEMIC ENCEPHALITOZOONOSIS DUE TO ENCEPHALITOZOON CUNICULI STRAIN IV IN A VANCOUVER ISLAND MARMOT ( MARMOTA VANCOUVERENSIS).

J Zoo Wildl Med 2018 Jun;49(2):484-488

  A 2-mo-old Vancouver Island marmot ( Marmota vancouverensis), housed at a quarantined breeding facility, presented for acute obtundation and vestibular ataxia. Physical examination revealed poor growth compared with littermates, poor nutritional condition, and mild dehydration. The animal's condition deteriorated over 24 hr, and it was euthanized following the development of generalized seizures. Read More

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June 2018
7 Reads

First characterization of a microsporidial triosephosphate isomerase and the biochemical mechanisms of its inactivation to propose a new druggable target.

Sci Rep 2018 Jun 5;8(1):8591. Epub 2018 Jun 5.

Grupo de Investigación en Biomoléculas, Laboratorio de Errores Innatos del Metabolismo y Tamiz, Instituto Nacional de Pediatría, Ciudad de México, 04530, Mexico.

The microsporidia are a large group of intracellular parasites with a broad range of hosts, including humans. Encephalitozoon intestinalis is the second microsporidia species most frequently associated with gastrointestinal disease in humans, especially immunocompromised or immunosuppressed individuals, including children and the elderly. The prevalence reported worldwide in these groups ranges from 0 to 60%. Read More

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June 2018
3 Reads

Intestinal microsporidiosis in Strasbourg from 2014 to 2016: emergence of an Enterocytozoon bieneusi genotype of Asian origin.

Emerg Microbes Infect 2018 Jun 6;7(1):97. Epub 2018 Jun 6.

Institute of Parasitology and Tropical Diseases, EA 7292, University of Strasbourg, 3 rue Koeberlé, Strasbourg, France.

Microsporidia cause opportunistic infections in highly immunodeficient individuals. Few studies on the epidemiology of these infections have been conducted in France. Between 2014 and 2016, we undertook a study to estimate the prevalence and circulating genotypes of this fungus-related micro-organism among the population of Strasbourg University Hospital. Read More

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June 2018
3 Reads

Seroprevalence Survey for Microsporidia in Common Bottlenose Dolphin ( Tursiops truncatus): Example of A Quantitative Approach Based on Immunoblotting.

J Wildl Dis 2018 May 9. Epub 2018 May 9.

1 University of Miami, Division of Comparative Pathology, Department of Pathology & Laboratory Medicine, Miller School of Medicine, Miami, Florida 33136, USA.

Little is known about microsporidiosis pathogenicity in cetaceans. Here we report seroprevalence of 76% for microsporidia in blood samples from common bottlenose dolphins ( Tursiops truncatus), from animals managed under human care ( n=108) or captured for health assessments ( n=13) and released. Read More

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May 2018
4 Reads

Molecular surveillance of Vittaforma-like microsporidia by a small-volume procedure in drinking water source in Taiwan: evidence for diverse and emergent pathogens.

Environ Sci Pollut Res Int 2018 Jul 30;25(19):18823-18837. Epub 2018 Apr 30.

Graduate Institute of Life Sciences, National Defense Medical Center, No. 161, Section 6, Minquan East Road, Neihu District, Taipei City, 114, Taiwan.

Vittaforma corneae belongs to microsporidia, which include over 1500 species of opportunistic obligate intracellular fungi infecting almost all known animal taxa. Although outbreaks of ocular infections caused by waterborne V. corneae have been reported in recent years, little is known about the occurrence of this pathogen in aquatic environments. Read More

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July 2018
9 Reads
2.83 Impact Factor

Human-Pathogenic Enterocytozoon bieneusi in Captive Giant Pandas (Ailuropoda melanoleuca) in China.

Sci Rep 2018 Apr 26;8(1):6590. Epub 2018 Apr 26.

The Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, 611100, China.

Human and animal infections of Enterocytozoon bieneusi (E. bieneusi) have consistently been reported worldwide, garnering public attention; however, the molecular epidemiology of E. bieneusi in the giant panda remains limited. Read More

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April 2018
5 Reads

Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.

Am J Trop Med Hyg 2018 Jul 19;99(1):90-93. Epub 2018 Apr 19.

Institut National de la Santé et de la Recherche Médicale, Unité 995-Lille Inflammation Research International Center, Fungal Associated Invasive & Inflammatory Diseases, Lille, France.

Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. Read More

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July 2018
1 Read

Anterior segment optical coherence tomography of microsporidial keratoconjunctivitis.

Indian J Ophthalmol 2018 05;66(5):691-692

Department of Ophthalmology, Krishna Institute of Medical Sciences Limited, Hyderabad, Telangana, India.

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May 2018
3 Reads

A new microsporidium Percutemincola moriokae gen. nov., sp. nov. from Oscheius tipulae: A novel model of microsporidia-nematode associations.

Parasitology 2018 Apr 17:1-12. Epub 2018 Apr 17.

Department of Immunobiology,School of Pharmacy,Iwate Medical University,Nishitokuta 2-1-1,Yahaba,Shiwa,Iwate,Japan.

Here, we describe a new microsporidium Percutemincola moriokae gen. nov., sp. Read More

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April 2018
5 Reads

Prevalence and genotypes of Enterocytozoon bieneusi in China.

Acta Trop 2018 Jul 13;183:142-152. Epub 2018 Apr 13.

College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China. Electronic address:

Enterocytozoon bieneusi has been considered as the most frequently diagnosed microsporidian species in humans and various animal species, accounting for more than 90% of the cases of human microsporidiosis. Spores of this pathogen excreted from both symptomatic and asymptomatic hosts into environment also would be an important source of waterborne outbreak of microsporidiosis. Due to limited effective drugs available but with too much side effects to mammals (eg. Read More

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July 2018
3 Reads

Evaluation of four commercial DNA extraction kits for the detection of Microsporidia and the importance of pretreatments in DNA isolation.

Acta Parasitol 2018 Jun;63(2):386-392

Department of Parasitology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

Microsporidia are obligate intracellular parasitic protozoa infecting the wide variety of hosts and are commonly known as a cause of chronic diarrhea particularly in immunocompromised individuals. Molecular-based tests have high sensitivity and specificity in disease diagnosis. However, these tests' performance relies on the isolation of DNA in a good concentration. Read More

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June 2018
5 Reads

El phylum Microsporidia.

Rev Chilena Infectol 2018;35(1):73-74

Universidad de Valparaíso, Chile.

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May 2018
2 Reads

Renal Microsporidiosis in Pediatric Bone Marrow Transplant Recipients: A Case Series.

Turk Patoloji Derg 2018 Apr 9. Epub 2018 Apr 9.

Department of Histopathology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA.

Microsporidiosis is a rare, but emerging opportunistic infection in solid organ transplant and stem cell transplant recipients. Renal involvement in microsporidiosis is very rarely seen in these recipients. We describe two cases of pediatric renal microsporidiosis, diagnosed on renal biopsies, following bone marrow transplantation presenting as severe acute kidney injury. Read More

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April 2018
5 Reads

Confirmed microsporidial graft infection in a HIV-negative renal transplant recipient: A case report and review of the literature.

Transpl Infect Dis 2018 Jun 10;20(3):e12888. Epub 2018 Apr 10.

Department of Nephrology, Monash Health, Clayton, VIC, Australia.

Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV-infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. Read More

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Visual loop-mediated isothermal amplification (LAMP) for the rapid diagnosis of Enterocytozoon hepatopenaei (EHP) infection.

Parasitol Res 2018 May 17;117(5):1485-1493. Epub 2018 Mar 17.

ICAR-Central Institute of Brackishwater Aquaculture, #75 Santhome High Road, Raja Annamalai Puram, Chennai, 600028, India.

The emerging microsporidian parasite Enterocytozoon hepatopenaei (EHP), the causative agent of hepatopancreatic microsporidiosis, has been widely reported in shrimp-farming countries. EHP infection can be detected by light microscopy observation of spores (1.7 × 1 μm) in stained hepatopancreas (HP) tissue smears, HP tissue sections, and fecal samples. Read More

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May 2018
11 Reads

Identification, characterization and heparin binding capacity of a spore-wall, virulence protein from the shrimp microsporidian, Enterocytozoon hepatopenaei (EHP).

Parasit Vectors 2018 03 12;11(1):177. Epub 2018 Mar 12.

Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand.

Background: The microsporidian Enterocytozoon hepatopenaei (EHP) is a spore-forming, intracellular parasite that causes an economically debilitating disease (hepatopancreatic microsporidiosis or HPM) in cultured shrimp. HPM is characterized by growth retardation and wide size variation that can result in economic loss for shrimp farmers. Currently, the infection mechanism of EHP in shrimp is poorly understood, especially at the level of host-parasite interaction. Read More

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March 2018
8 Reads

A new scope for orlistat: Effect of approved anti-obesity drug against experimental microsporidiosis.

Med Mycol 2018 Feb 24. Epub 2018 Feb 24.

Department of Medical Parasitology.

As the current therapies for intestinal microsporidiosis are either inconsistent in their efficacies or hampered by several adverse effects, alternative antimicrosporidial agents are being sought. The present study is the first that was designed to evaluate the potency of orlistat, an approved anti-obesity drug, against intestinal microsporidiosis caused by both Enterocytozoon bieneusi and Encephalitozoon intestinalis. Results were assessed through studying fecal and intestinal spore load, intestinal histopathological changes, viability, and infectivity of spores from treated animals. Read More

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February 2018
2 Reads

Prevalence, genotypes, and risk factors of Enterocytozoon bieneusi in Asiatic black bear (Ursus thibetanus) in Yunnan Province, Southwestern China.

Parasitol Res 2018 Apr 15;117(4):1139-1145. Epub 2018 Feb 15.

College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province, 650201, People's Republic of China.

Microsporidiosis is an important zoonotic disease, even leading to severe diarrhea. However, no information about prevalence and genotypes of Enterocytozoon bieneusi infection in Asiatic black bears in southwestern China is available. The objectives of the present study were to investigate the prevalence of E. Read More

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April 2018
3 Reads

Highly sensitive electrochemical assay for Nosema bombycis gene DNA PTP1 via conformational switch of DNA nanostructures regulated by H from LAMP.

Biosens Bioelectron 2018 May 2;106:186-192. Epub 2018 Feb 2.

Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. Electronic address:

The portable and rapid detection of biomolecules via pH meters to monitor the concentration of hydrogen ions (H) from biological reactions (e.g. loop-mediated isothermal amplification, LAMP) has attracted research interest. Read More

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May 2018
3 Reads

Wildlife as an environmental reservoir of Enterocytozoon bieneusi (Microsporidia) – analyses of data based on molecular methods

Ann Parasitol 2017;63(4):265-281

Department of Parasitology, Institute of Genetics and Microbiology, Wrocław University, ul. Przybyszewskiego 63, 51-148 Wrocław, Poland

Enterocytozoon bieneusi is the most commonly identified Microsporidia in humans and has also been detected worldwide in a large group of wild living and domestic animals. The identification of E. bieneusi in wildlife has raised the question of the importance of animal reservoirs in the epidemiology of microsporidiosis and the implications of the infection with this pathogen in hosts. Read More

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May 2018
1 Read

Survival of Bacterial and Parasitic Pathogens from Zebrafish (Danio rerio) After Cryopreservation and Thawing.

Zebrafish 2018 04 25;15(2):188-201. Epub 2018 Jan 25.

1 Department of Microbiology, Oregon State University , Corvallis, Oregon.

Cryopreservation is a common method used to preserve the sperm of various animal species, and it is widely used with zebrafish (Danio rerio). As with other animals, there is a possibility of paternal pathogen transmission through sperm. We evaluated the ability of five common and important pathogens of zebrafish to survive cryopreservation as used with zebrafish sperm and freezing without cryopreservant. Read More

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April 2018
3 Reads

Enterocytozoon bieneusi genotypes in Tibetan sheep and yaks.

Parasitol Res 2018 Mar 14;117(3):721-727. Epub 2018 Jan 14.

Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA.

Few studies have been conducted on the distribution of Enterocytozoon bieneusi genotypes in Tibetan sheep and yaks, which live outdoors in extreme climate with high altitude. In this study, fecal specimens from 312 Tibetan sheep and 554 yaks in Qinghai, China, were collected and examined for E. bieneusi by PCR-sequence analysis of the ribosomal internal transcribed spacer. Read More

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March 2018
9 Reads
2.33 Impact Factor

Divergent Cryptosporidium parvum subtype and Enterocytozoon bieneusi genotypes in dromedary camels in Algeria.

Parasitol Res 2018 Mar 6;117(3):905-910. Epub 2018 Jan 6.

Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA, 30329, USA.

Little information is available on the occurrence of the zoonotic protists Cryptosporidium spp. and none on Enterocytozoon bieneusi in camels. This preliminary study was conducted to examine the identity of Cryptosporidium subtypes and E. Read More

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March 2018
10 Reads

Prevalence of Cryptosporidium, microsporidia and Isospora infection in HIV-infected people: a global systematic review and meta-analysis.

Parasit Vectors 2018 01 9;11(1):28. Epub 2018 Jan 9.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.

Background: Diarrhea caused by opportunistic intestinal protozoa is a common problem in HIV infection. We aimed to establish the prevalence of Cryptosporidium, misrosporidia, and Isospora in HIV-infected people using a systematic review and meta-analysis, which is central to developing public policy and clinical services.

Methods: We searched PubMed, ScienceDirect, Google Scholar, Embase, Chinese Web of Knowledge, Wanfang, and Chongqing VIP databases for studies reporting Cryptosporidium, microsporidia, or Isospora infection in HIV-infected people. Read More

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January 2018
5 Reads

Intestinal microsporidiosis in Iran: infection in immune-compromised and immunocompetent patients.

Curr Med Mycol 2017 Mar;3(1):30-36

Regional Knowledge Hub and WHO Collaborating Centre for HIV Surveillance, Kerman University of Medical Sciences, Kerman, Iran.

Background And Purpose: Gastroenteritis and the clinical profile caused by , an opportunistic pathogen, may be severe in immunocompromised individuals, especially in AIDS patients. Conventionally, it is necessary to detect the small infective spores in stained smears. However, due to the limitations of the microscopy-based methods, several DNA-based methods such as polymerase chain reaction (PCR) have recently been developed to enhance diagnosis sensitivity. Read More

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March 2017
18 Reads

MICROSPORIDIOSIS IN PEPPERMINT SHRIMP (DECAPODA: HIPPOLYTIDAE: LYSMATA SPP.).

J Zoo Wildl Med 2017 Dec;48(4):1223-1229

Microsporidia are a diverse, parasitic phylum closely related to fungi. They infect a broad range of host species and tissues. This report describes microsporidiosis infection in a captive, wild-caught peppermint shrimp ( Lysmata spp. Read More

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December 2017
5 Reads

First detection and genetic characterisation of Enterocytozoon bieneusi in wild deer in Melbourne's water catchments in Australia.

Parasit Vectors 2018 01 3;11(1). Epub 2018 Jan 3.

Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC, 3010, Australia.

Background: Enterocytozoon bieneusi is reported to be a common microsporidian of humans and animals in various countries. However, E. bieneusi has yet to be recorded in animals in Australia. Read More

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January 2018
7 Reads

Dominance of the Enterocytozoon bieneusi genotype BEB6 in red deer (Cervus elaphus) and Siberian roe deer (Capreolus pygargus) in China and a brief literature review.

Parasite 2017 21;24:54. Epub 2017 Dec 21.

Department of Parasitology, Harbin Medical University, Harbin, Heilongjiang 150081, PR China.

Enterocytozoon bieneusi is the most frequently diagnosed microsporidian species in humans and is also found in a wide range of animals. It is considered to be an important but neglected zoonotic pathogen. With the development of deer bred in captivity, the number of deer has been increasing in recent years in China and there are more people involved in this work. Read More

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July 2018
10 Reads

Molecular diagnosis of human microsporidian infections.

Trans R Soc Trop Med Hyg 2017 Sep;111(9):382-383

Research Service (151), Corporal Michael J. Crescenz Department of Veterans Affairs (VA) Medical Center, University and Woodland Avenues, Philadelphia, PA 19104, USA.

With the transformation of HIV infection from an acutely life-threatening disease into a chronic condition (as a consequence of the development of effective antiretroviral medication), the perceived clinical importance of diagnosing and treating microsporidian infections diminished, at least in industrialized countries. In locales where effective antiretroviral therapy is not available, as well as in patients with immunodeficiency for reasons other than HIV infection (e.g. Read More

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September 2017
3 Reads

Zoonotic and host-adapted genotypes of Cryptosporidium spp., Giardia duodenalis and Enterocytozoon bieneusi in dairy cattle in Hebei and Tianjin, China.

Vet Parasitol 2017 Dec 2;248:68-73. Epub 2017 Nov 2.

College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; International Joint Research Laboratory for Zoonotic Diseases of Henan, Zhengzhou, China. Electronic address:

A total of 1040 fecal samples, collected from 12 dairy cattle farms in Hebei and Tianjin, near the Bohai area of China, were screened for Cryptosporidium spp., Giardia duodenalis and Enterocytozoon bieneusi by polymerase chain reaction. The overall prevalence for Cryptosporidium, G. Read More

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December 2017
12 Reads

Clinical Signs, Diagnosis, and Treatment of Encephalitozoon cuniculi Infection in Rabbits.

Vet Clin North Am Exot Anim Pract 2018 Jan;21(1):69-82

Pet Care Veterinary Hospital, 5201 Virginia Beach Boulevard, Virginia Beach, VA 23462, USA.

Central vestibular dysfunction caused by Encephalitozoon cuniculi frequently mimics the condition of a peripheral disorder. A negative antibody titer rules out E cuniculi as the cause of present clinical signs. Cerebrospinal fluid analysis including polymerase chain reaction is considered an inappropriate diagnostic method for in vivo diagnosis of encephalitozoonosis. Read More

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January 2018
4 Reads

Ultrastructural and molecular characterization of Vairimorpha austropotamobii sp. nov. (Microsporidia: Burenellidae) and Thelohania contejeani (Microsporidia: Thelohaniidae), two parasites of the white-clawed crayfish, Austropotamobius pallipes complex (Decapoda: Astacidae).

J Invertebr Pathol 2018 Jan 6;151:59-75. Epub 2017 Nov 6.

Department of Earth and Environmental Sciences, University of Pavia, Via Adolfo Ferrata 7, I-27100 Pavia, Italy.

The microsporidiosis of the endangered white-clawed crayfish Austropotamobius pallipes complex has generally been attributed to only one species, Thelohania contejeani, the agent of porcelain disease. Species identification was mostly assessed by macroscopic examination or microscopic evaluation of muscle samples rather than by molecular or ultrastructural analyses. A survey conducted on A. Read More

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January 2018
13 Reads

Production and characterization of monoclonal antibodies against Encephalitozoon intestinalis and Encephalitozoon sp. spores and their developmental stages.

Parasit Vectors 2017 Nov 9;10(1):560. Epub 2017 Nov 9.

Laboratorio de Parasitología, Universidad San Pablo CEU, Madrid, Spain.

Background: Microsporidia are intracellular obligate parasites traditionally associated with immunosuppressed patients; their detection in immunocompetent patients has increased, highlighting their possible importance as emerging pathogens. Detection of spores in stools, urine, body fluids and tissues is difficult and immunological techniques such as immunofluorescence have proved to be a useful and reliable tool in the diagnosis of human microsporidiosis. For this reason, we have produced and characterized monoclonal antibodies (MAbs) specific for Encephalitozoon intestinalis (the second most frequent microsporidian infecting humans), and other Encephalitozoon species, that can be used in different diagnostic techniques. Read More

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November 2017
7 Reads

Diabetes mellitus increases the susceptibility to encephalitozoonosis in mice.

PLoS One 2017 1;12(11):e0186954. Epub 2017 Nov 1.

Programa de Patologia Ambiental e Experimental, Universidade Paulista (UNIP), São Paulo, Brasil.

Microsporidiosis are diseases caused by opportunistic intracellular fungi in immunosuppressed individuals, as well as in transplanted patients, the elderly and children, among others. Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia and decreased T cell response, neutrophil function, humoral immunity failure, increasing the susceptibility to infections. Here, we investigated the susceptibility of streptozotocin (STZ)-induced type I diabetic and/or immunosuppressed mice to encephalitozoonosis by Encephalitozoon cuniculi. Read More

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November 2017
7 Reads

Morphology and phylogeny of Ameson portunus n. sp. (Microsporidia) infecting the swimming crab Portunus trituberculatus from China.

Eur J Protistol 2017 Oct 27;61(Pt A):122-136. Epub 2017 Sep 27.

Key Laboratory of East China Sea Fishery Resources Exploitation, Ministry of Agriculture; East China Sea Fisheries Research Institute, China Academy of Fishery Sciences, Shanghai 200090, China. Electronic address:

Ameson portunus n. sp. is a new microsporidian species that infects the skeletal muscle of Portunus trituberculatus, a pond-reared swimming crab from China. Read More

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October 2017
4 Reads

Transmission of Pseudoloma neurophilia in Laboratory Zebrafish (Danio rerio) When Using Mass Spawning Chambers and Recommendations for Chamber Disinfection.

Zebrafish 2018 02 19;15(1):63-72. Epub 2017 Oct 19.

1 Tri-Institutional Training Program in Laboratory Animal Medicine and Science , New York, New York.

Pseudoloma neurophilia, a microsporidium that primarily infects neural tissues, is a common pathogen in laboratory zebrafish. The risk of parasite transmission with different spawning apparatuses and the effectiveness of disinfection are unknown. In this study, we spawned uninfected zebrafish with P. Read More

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February 2018
1 Read

Population genetics of Enterocytozoon bieneusi in captive giant pandas of China.

Parasit Vectors 2017 Oct 18;10(1):499. Epub 2017 Oct 18.

The Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Sichuan Province, China.

Background: Most studies on Enterocytozoon bieneusi are conducted based on the internal transcribed spacer (ITS) region of the rRNA gene, whereas some have examined E. bieneusi population structures. Currently, the population genetics of this pathogen in giant panda remains unknown. Read More

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October 2017
5 Reads

Limited effect of adaptive immune response to control encephalitozoonosis.

Parasite Immunol 2017 Dec 1;39(12). Epub 2017 Nov 1.

Institute of Parasitology, BC CAS, v.v.i., České Budějovice, Czech Republic.

This study revises our understanding of the effectiveness of cell-mediated adaptive immunity and treatment against microsporidia using molecular detection and quantification of microsporidia in immunocompetent C57Bl/6 and immunodeficient CD4 and CD8 mice for the first time. We demonstrate an intense dissemination of microsporidia into most organs within the first weeks post-infection in all strains of mice, followed by a chronic infection characterized by microsporidia persistence in CD4 and C57Bl/6 mice and a lethal outcome for CD8 mice. Albendazole application reduces microsporidia burden in C57Bl/6 and CD4 mice, whereas CD8 mice experience only a temporary effect of the treatment. Read More

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December 2017
2 Reads

Infection by and genotype characteristics of Enterocytozoon bieneusi in HIV/AIDS patients from Guangxi Zhuang autonomous region, China.

BMC Infect Dis 2017 10 13;17(1):684. Epub 2017 Oct 13.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Key Laboratory of Parasite and Vector Biology, Ministry of Health, WHO Collaborating Center for Tropical Diseases, 207 Rui Jin Er Road, Shanghai, 200025, China.

Background: Enterocytozoon bieneusi has been increasingly reported to infect humans and various mammals. Microsporidia cause diarrhea in HIV-infected patients worldwide. PCR amplification and sequencing based on the internal transcribed spacer region have been used to describe the genotypes of E. Read More

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October 2017
4 Reads