266 results match your criteria Microcystic Adnexal Carcinoma


Factors associated with the utilization of Mohs surgery in the treatment of microcystic adnexal carcinoma.

J Am Acad Dermatol 2019 Feb 2. Epub 2019 Feb 2.

Department of Dermatology, University of Minnesota, Minneapolis, MN.

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https://linkinghub.elsevier.com/retrieve/pii/S01909622193018
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http://dx.doi.org/10.1016/j.jaad.2019.01.069DOI Listing
February 2019
5 Reads

Successful treatment of microcystic adnexal carcinoma on the philtrum with oral S-1 monotherapy.

J Dermatol 2019 Jan 21. Epub 2019 Jan 21.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1111/1346-8138.14770DOI Listing
January 2019
2 Reads

Immunoreactivity for Sox10 in Basaloid Neoplasms of The Skin.

Appl Immunohistochem Mol Morphol 2019 Feb;27(2):114-118

Section of Dermatopathology, Division of Surgical Pathology-Cytopathology, University of Virginia Medical Center, Charlottesville, VA.

Basaloid tumors of the skin pose a diagnostic challenge to pathologists, because the differential diagnosis is broad, sometimes with subtle differentiating features. We evaluated SOX10 expression in 120 primary cutaneous tumors with epidermal, sweat glandular, neuroendocrine/neuroectodermal, follicular, and sebaceous lineages. Our findings were compared with those of previous studies that evaluated SOX10 in tumors of the skin. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000721DOI Listing
February 2019
3 Reads

Malignant Sweat Gland Tumors.

Hematol Oncol Clin North Am 2019 Feb;33(1):53-71

Department of Pathology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA. Electronic address:

Malignant sweat gland neoplasms are a confusing area within dermatopathology, with many entities reported under several designations in the literature. This review describes the key clinical and histopathologic features of select malignant adnexal neoplasms, including porocarcinoma, papillary carcinoma, adenoid cystic carcinoma, cribriform carcinoma, apocrine hidradenocarcinoma, malignant mixed tumor of the skin, syringoid carcinoma, cylindrocarcinoma, spiradenocarcinoma, mucinous carcinoma, polymorphous sweat gland carcinoma, microcystic adnexal carcinoma, secretory carcinoma of the skin, and primary cutaneous signet ring cell carcinoma. For entities with overlapping features, differential diagnoses are discussed. Read More

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http://dx.doi.org/10.1016/j.hoc.2018.09.002DOI Listing
February 2019
6 Reads

Microcystic adnexal carcinoma of the skin in atypical site (pubic region): clinical and dermatoscopic features.

G Ital Dermatol Venereol 2018 Sep 20. Epub 2018 Sep 20.

Histopathology Service of the "Celio" Military Hospital of Rome, Rome, Italy.

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https://www.minervamedica.it/index2.php?show=R23Y9999N00A180
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http://dx.doi.org/10.23736/S0392-0488.18.05893-5DOI Listing
September 2018
13 Reads

Microcystic adnexal carcinoma of the external auditory canal.

Cutis 2018 08;102(2):E11-E13

Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, and Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Taiwan.

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August 2018
8 Reads

Solid carcinoma is a variant of microcystic adnexal carcinoma: A 14-case series.

J Cutan Pathol 2018 Dec 9;45(12):897-904. Epub 2018 Oct 9.

Dermatologist and Dermatopathologist, Friedrichshafen Dermatopathologie, Friedrichshafen, Germany.

Background: Solid carcinoma is a poorly characterized malignant apocrine neoplasm as only 16 cases have been published.

Objective: To characterize its clinical, histopathological, and immunohistochemical features.

Methods: We compiled 14 cases of solid carcinoma and clinical information were updated. Read More

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http://doi.wiley.com/10.1111/cup.13351
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http://dx.doi.org/10.1111/cup.13351DOI Listing
December 2018
23 Reads
1.560 Impact Factor

Microcystic Adnexal Carcinoma of the Nipple.

Wounds 2018 Jun;30(6):E65-E67

Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN.

Background: Microcystic adnexal carcinoma (MAC) is a rare infiltrative cutaneous tumor, but with its locally aggressive nature, high rate of recurrence, and rare metastatic potential, it is an important clinical entity to consider when faced with a nipple lesion. These tumors are frequently misdiagnosed based on superficial biopsy alone.

Case Report: This case of a 15-year-old girl with MAC of the nipple demonstrates the importance of having a high index of suspicion in order to obtain a diagnosis, to determine the extent of disease, and to achieve adequate resection before reconstruction. Read More

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June 2018
20 Reads

An Unusual Morphological Presentation of Cutaneous Squamous Cell Carcinoma Mimicking Microcystic Adnexal Carcinoma: A Diagnostic Pitfall.

Dermatopathology (Basel) 2018 Apr-Jun;5(2):64-68. Epub 2018 May 23.

Department of Dermatology and Venereology, University Hospital of Geneva, Geneva, Switzerland.

Cutaneous squamous cell carcinoma (SCC) exhibiting microcystic adnexal carcinoma-like differentiation is an extremely rare tumor that shows both squamous and ductal differentiation. This tumor is often misdiagnosed clinically and histologically and is confused with other malignant and benign cutaneous neoplasms. It usually occurs in middle-aged to older adults. Read More

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http://dx.doi.org/10.1159/000488981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031951PMC
May 2018
24 Reads

Sclerosing Microcystic Adenocarcinoma: Report of a Rare Case and Review of Literature.

Head Neck Pathol 2018 Jul 10. Epub 2018 Jul 10.

Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.

Sclerosing microcystic adenocarcinoma is an exceedingly rare entity occurring in the mucosal surfaces of the head and neck that closely resembles cutaneous microcystic adnexal carcinoma. Here, we report a case of sclerosing microcystic adenocarcinoma that presented as a vague mass at the floor of the mouth in a 55-year-old woman. The pathology features and the diagnostic challenges, especially in the biopsy and margin evaluation are discussed here. Read More

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http://link.springer.com/10.1007/s12105-018-0945-z
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http://dx.doi.org/10.1007/s12105-018-0945-zDOI Listing
July 2018
30 Reads

Cutaneous Squamous Cell Carcinoma With Sclerosing Features: An Uncommon and Potentially Aggressive Variant.

Am J Dermatopathol 2018 Aug;40(8):575-579

Department of Pathology, Section of Dermatopathology, University of Virginia Health System, Charlottesville, VA.

Sclerosing squamous cell carcinoma (SCC), also known as "desmoplastic" SCC, is a rare subtype of cutaneous malignancy. This variant is clinically significant because it is associated with an increased risk of local recurrence and metastasis. We herein present 16 examples of sclerotic SCC of the skin in 8 men and 3 women, with a median age of 66 years. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001169DOI Listing
August 2018
15 Reads

Utility of Ber-EP4 and MOC-31 in Basaloid Skin Tumor Detection.

Appl Immunohistochem Mol Morphol 2018 Apr 7. Epub 2018 Apr 7.

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.

Ber-EP4 has been the traditional immunostain used for the detection of basaloid skin tumors. Recently, MOC-31 has shown be superior to Ber-EP4 in the detection of basosquamous basal cell carcinoma (BCC) and many centers are now using both Ber-EP4 and MOC-31 antibodies together to detect these lesions. The objective of this study was to compare the utility of using both Ber-EP4 and MOC-31 immunostains in the detection of basaloid skin tumors and to better characterize the previously unknown staining properties of MOC-31 in cutaneous lesions. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000664DOI Listing
April 2018
5 Reads

[Microcystic adnexal carcinoma: A case report].

Ann Pathol 2018 Jun 2;38(3):198-201. Epub 2018 Apr 2.

Service de dermatologie, CHU de Caen, avenue côte-de-nacre, 14033 Caen, France.

We report a case of microcystic adnexal carcinoma in a 80-year-old woman. This is a rare malignant adnexal cutaneous tumor with glandular and follicular differentiation, rare, often asymptomatic, with late diagnosis and slow growth, locally aggressive and rarely metastatic. The distinction with other benign and malignant skin tumors is difficult. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02426498183001
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http://dx.doi.org/10.1016/j.annpat.2018.03.001DOI Listing
June 2018
23 Reads

Microcystic adnexal carcinoma-diagnostic criteria and therapeutic methods: case report and review of the literature.

Int J Oral Maxillofac Surg 2018 Oct 27;47(10):1258-1262. Epub 2018 Mar 27.

Department of Maxillofacial Surgery, University Hospital Dubrava, Zagreb, Croatia. Electronic address:

Microcystic adnexal carcinoma (MAC) is a rare, infiltrating, locally aggressive cutaneous neoplasm of combined follicular and eccrine/apocrine histogenesis, usually presenting on the upper lip or face. Differentiation from other adnexal tumours is very important because the clinical management of these tumours is radically different, and misdiagnosis may lead to incorrect treatment. A case of recurrent MAC in the upper lip, treated with multiple excisions and postoperative radiation therapy (PORT), is presented herein. Read More

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http://dx.doi.org/10.1016/j.ijom.2018.03.001DOI Listing
October 2018
7 Reads

Demographics and outcomes of microcystic adnexal carcinoma.

J Am Acad Dermatol 2018 Oct 17;79(4):756-758. Epub 2018 Mar 17.

Department of Dermatology, Mayo Clinic, Rochester, Minnesota. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183046
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http://dx.doi.org/10.1016/j.jaad.2018.03.010DOI Listing
October 2018
9 Reads

Polymorphous Sweat Gland Carcinoma: An Immunohistochemical and Molecular Study.

Am J Dermatopathol 2018 Aug;40(8):580-587

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI.

Polymorphous sweat gland carcinoma is an uncommon low-grade malignant adnexal tumor with a marked predilection for the distal extremities. Histologically, the lesions are characterized by a cellular proliferation showing a combination of growth patterns, including trabecular, solid, tubular, cribriform, or adenoid cystic and pseudopapillary. The immunohistochemical and molecular profile of these tumors has not yet been properly addressed. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001128DOI Listing
August 2018
7 Reads

A case and literature review of orbital microcystic adnexal carcinoma.

Orbit 2018 Dec 20;37(6):472-475. Epub 2018 Feb 20.

a Department of Ophthalmology , Leicester Royal Infirmary , Leicester , England, UK.

Microcystic adnexal carcinoma (MAC) is a very rare and locally aggressive sweat gland tumour. MAC has been well reported presenting as a periocular cutaneous lesion, rarely with subsequent direct orbital invasion and only once as a primary orbital lesion. Local recurrence is frequent after primary surgical excision and the role of adjuvant radiotherapy is ill-defined. Read More

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http://dx.doi.org/10.1080/01676830.2018.1440607DOI Listing
December 2018
12 Reads

Microcystic adnexal carcinoma with sebaceous differentiation: Three cases.

J Cutan Pathol 2018 Apr 15;45(4):290-295. Epub 2018 Feb 15.

Private Practice, Friedrischafen, Friedrichshafen Dermatopathologie, Friedrischafen, Germany.

Microcystic adnexal carcinoma (MAC) is a low-grade malignant tumor of the skin. Histologically, this tumor shows a biphasic pattern, with cords and nests of basaloid cells, as well as keratin horn cysts. This biphasic histological appearance has been interpreted by some authors as a sign of double eccrine and folliculosebaceous-apocrine differentiation, whereas some other authors defend a solely eccrine differentiation. Read More

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http://dx.doi.org/10.1111/cup.13109DOI Listing
April 2018
12 Reads

Primary cutaneous secretory carcinoma: A previously overlooked low-grade sweat gland carcinoma.

J Cutan Pathol 2018 Mar 10;45(3):240-245. Epub 2018 Jan 10.

Friedrichshafen Dermatopathologie, Friedrichshafen, Germany.

Introduction: Twelve cases of primary cutaneous secretory carcinoma (PCSC) have been published, 9 showing ETV6-NTRK3 translocation, a characteristic finding shared with secretory breast carcinoma and mammary analogue secretory carcinoma.

Case Report: A 34-year-old female presented a solitary nodule on the right groin. Biopsy revealed a secretory carcinoma staining positive with CK7, CAM5. Read More

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http://dx.doi.org/10.1111/cup.13092DOI Listing
March 2018
4 Reads

Microcystic adnexal carcinoma of the orbit mimicking pagetoid sebaceous gland carcinoma.

Orbit 2018 Jun 20;37(3):235-237. Epub 2017 Oct 20.

d Medical Director, MN Eye Hospital , Chennai , India.

Microcystic adnexal carcinoma (MAC) is a rare malignancy of sweat glands that has been reported most often on the face in the form of a cutaneous lesion, with the potential for deeper invasion. The synonyms of MAC include sclerosing sweat duct carcinoma, syringomatous carcinoma, and malignant syringoma. Clinically, MAC in the periocular area has been misdiagnosed as basal cell carcinoma, squamous cell carcinoma, or even chalazia. Read More

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http://dx.doi.org/10.1080/01676830.2017.1383472DOI Listing
June 2018
8 Reads

Microcystic adnexal carcinoma mimicking basal cell carcinoma.

JAAD Case Rep 2017 Nov 9;3(6):492-494. Epub 2017 Oct 9.

Department of Dermatology, University Hospital of Salamanca, Salamanca, Spain.

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http://dx.doi.org/10.1016/j.jdcr.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635954PMC
November 2017
9 Reads

Metastatic Microcystic Adnexal Carcinoma with DNA Sequencing Results and Response to Systemic Antineoplastic Chemotherapy.

Anticancer Res 2017 09;37(9):5109-5111

Section of Satellite Oncology, Moffitt Cancer Center and Division of Hematology/Oncology, Morsani School of Medicine, University of South Florida, Tampa, FL, U.S.A.

Microcystic adnexal carcinoma (MAC) is a rare cutaneous malignancy. Due to its rarity, the molecular characteristics and treatment for metastatic MAC remain undefined. Here we present, as far as we are aware, the first case of metastatic MAC with DNA sequencing results indicating a mutation in TP53 and chromosomal losses in cyclin dependent kinase inhibitor 2A (CDKN2A) and cyclin dependent kinase inhibitor 2B (CDKN2B). Read More

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http://dx.doi.org/10.21873/anticanres.11929DOI Listing
September 2017
9 Reads

Microcystic Adnexal Carcinoma and a Summary of Other Rare Malignant Adnexal Tumours.

Authors:
Arif Aslam

Curr Treat Options Oncol 2017 08;18(8):49

St Helens and Knowsley Teaching Hospitals NHS Trust, Marshalls Cross Road, St Helens, WA9 3DA, UK.

Opinion Statement: Microcystic adnexal carcinoma (MAC) is a rare, slow-growing, infiltrative malignant tumour most commonly found on the head and neck. It often presents as a solitary skin-coloured or yellow papule, plaque or nodule. Ultraviolet radiation, immunosuppression and ionising radiation are possible risk factors. Read More

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http://dx.doi.org/10.1007/s11864-017-0491-zDOI Listing
August 2017
35 Reads

Microcystic Adnexal Carcinoma: A Review of the Literature.

Dermatol Surg 2017 Aug;43(8):1012-1016

*Division of Dermatology, Department of Internal Medicine, Washington University, St. Louis, Missouri; †Department of Pathology and Immunology, Washington University, St. Louis, Missouri.

Background: Microcystic adnexal carcinoma (MAC) is a rare, locally aggressive cutaneous neoplasm that commonly occurs on the face.

Objective: The purpose of this article is to comprehensively review the current literature on MAC pertaining to epidemiology, pathogenesis, clinical presentation, histology, immunohistochemistry, prognosis, follow-up, and treatment.

Materials And Methods: An extensive literature review was conducted using OVID MEDLINE and PubMed to identify articles relating to MAC. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001142DOI Listing
August 2017
32 Reads

Image Gallery: Microcystic adnexal carcinoma (syringomatous carcinoma and sclerosing sweat duct carcinoma) as an extensive sclerotic erythematous plaque with telangiectasia over the face.

Br J Dermatol 2017 06;176(6):e122

Department of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.

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http://dx.doi.org/10.1111/bjd.15479DOI Listing
June 2017
16 Reads

Longstanding microcystic adnexal carcinoma in a child.

Int J Dermatol 2017 Jul 23;56(7):782-783. Epub 2017 May 23.

Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1111/ijd.13657DOI Listing
July 2017
11 Reads

Update on Malignant Sweat Gland Tumors.

Surg Pathol Clin 2017 Jun 27;10(2):383-397. Epub 2017 Mar 27.

Department of Pathology, Western General Hospital, Alexander Donald Building, 1st Floor, Crewe Road, Edinburgh EH4 2XU, UK. Electronic address:

Malignant sweat gland tumors are rare cutaneous neoplasms, traditionally separated according to their behavior into low- and high-grade malignant. There is significant morphologic overlap, and outright malignant tumors may show relatively bland histologic features. They may, therefore, be mistaken easily for benign neoplasms. Read More

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http://dx.doi.org/10.1016/j.path.2017.01.010DOI Listing
June 2017
7 Reads

Adnexal Carcinomas Treated With Mohs Micrographic Surgery: A Comprehensive Review.

Dermatol Surg 2017 Oct;43(10):1199-1207

Surgical Dermatology Group, Birmingham, Alabama.

Background: Adnexal carcinomas (ACs) are rare cutaneous malignancies of sweat gland or pilosebaceous origin. Optimal treatment and metastatic potential of AC are poorly defined. Mohs micrographic surgery (MMS) has been increasingly used to treat AC. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001167DOI Listing
October 2017
14 Reads

An Aggressive Microcystic Adnexal Carcinoma Infiltrating the Sternum.

J Drugs Dermatol 2017 Feb;16(2):180-181

Microcystic adnexal carcinoma is a rare cutaneous tumor that is often misdiagnosed and has the potential to be aggressive. Mohs surgery is the treatment of choice to prevent recurrences. We present a case of a large recurrent microcystic adnexal carcinoma on the sternum, initially diagnosed as a basal cell carcinoma. Read More

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February 2017
6 Reads

Retrospective study of rare cutaneous malignant adnexal tumors of the head and neck in a tertiary care cancer hospital: a case series.

J Med Case Rep 2017 Mar 12;11(1):67. Epub 2017 Mar 12.

Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital & Research Centre, 7-A, Block-R3, Johar Town, Lahore, Pakistan.

Background: Adnexal tumors of the skin are a large and diverse group of benign and malignant neoplasms, which exhibit morphological differentiation toward one of the different types of adnexal epithelium present in normal skin and they pose a diagnostic challenge. The purpose of this study is to share our experience with these rare but aggressive tumors at a tertiary care cancer hospital in a developing country. A retrospective review of 11 patients diagnosed with rare adnexal tumors and their variants from January 2005 to December 2014, treated either surgically or non-surgically, was performed to describe the clinicopathological characteristics and outcome of the disease. Read More

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http://dx.doi.org/10.1186/s13256-017-1212-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346454PMC
March 2017
18 Reads

SCLEROSING MICROCYSTIC ADNEXAL CARCINOMA OF THE SCALP (CASE REPORT).

Georgian Med News 2016 Dec(261):12-14

Academic Teaching Hospital Dresden-Friedrichstadt, Department of Dermatology and Allergology; Institute of Pathology "Georg Schmorl"; Dresden, Germany.

Microcystic adnexal carcinoma is a rare malignant sweat gland tumor. We present the case report of a 63 year old male patient who developed this malignancy on the scalp, which is an uncommon site. The tumor has been removed by delayed MOHS technique with no relapse. Read More

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December 2016
3 Reads

Angiotropic syringomatous carcinoma.

J Cutan Pathol 2017 Apr 7;44(4):397-400. Epub 2017 Feb 7.

Department of Dermatology, Kurume University School of Medicine, Kurume, Japan.

Syringomatous carcinoma (SC) is a slow-growing malignant skin tumor that usually affects the face or scalp. An 83-year-old female developed SC on the sole, a rare location. Histopathologically, numerous ducts with few keratinizing cysts were seen in the upper dermis, and cords, strands and nests with sclerotic stroma were seen in the deep dermis and subcutis. Read More

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http://dx.doi.org/10.1111/cup.12893DOI Listing
April 2017
6 Reads

Microcystic adnexal carcinoma (MAC)-like squamous cell carcinoma as a differential diagnosis to Bell´s palsy: review of guidelines for refractory facial nerve palsy.

J Otolaryngol Head Neck Surg 2017 Jan 5;46(1). Epub 2017 Jan 5.

Department of Otolaryngology, Friedrich-Alexander University Erlangen-Nürnberg, Waldstrasse 1, Erlangen, 91054, Germany.

Background: Bell´s palsy is the most common cause of facial paralysis worldwide and the most common disorder of the cranial nerves. It is a diagnosis of exclusion, accounting for 60-75% of all acquired peripheral facial nerve palsies. Our case shows the first case of a microcystic adnexal carcinoma-like squamous cell carcinoma as a cause of facial nerve palsy. Read More

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http://dx.doi.org/10.1186/s40463-016-0180-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217411PMC
January 2017
2 Reads

Evidence-Based Medicine: Cutaneous Facial Malignancies: Nonmelanoma Skin Cancer.

Plast Reconstr Surg 2017 Jan;139(1):181e-190e

New York, N.Y. From the Dermatology Service and the Plastic Surgery Service, Memorial Sloan Kettering Cancer Center.

Learning Objectives: After studying this article, the participant should be able to: 1. Identify clinical features of nonmelanoma skin cancer; 2. Distinguish low-risk versus high-risk basal cell carcinoma and squamous cell carcinoma; 3. Read More

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http://dx.doi.org/10.1097/PRS.0000000000002853DOI Listing
January 2017
7 Reads

Incidence and Clinical Features of Rare Cutaneous Malignancies in Olmsted County, Minnesota, 2000 to 2010.

Dermatol Surg 2017 Jan;43(1):116-124

*Department of Dermatology, Mayo Clinic, Rochester, Minnesota;†Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Minnesota;‡Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota.

Background: The incidence of rare cutaneous malignancies is unknown. Current estimates of rare cutaneous malignancy incidences are based on broad epidemiologic data or single institution experiences, not population-based data.

Objective: To determine the incidence of several rare nonmelanoma skin cancers. Read More

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http://dx.doi.org/10.1097/DSS.0000000000000936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730059PMC
January 2017
13 Reads

Microcystic Adnexal Carcinoma of the Nasal Tip Treated With Surgical Excision and Rotational Forehead Skin Flap.

J Craniofac Surg 2016 Nov;27(8):e756-e758

*Department of Otorhinolaryngology†Department of Pathology‡Department of Plastic Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.

Microcystic adnexal carcinoma (MAC) is a rare malignant cutaneous adenocarcinoma that typically occurs in the head and neck, particularly at the central face. There are only slightly more than 300 patients reported worldwide, and most patients occur in Caucasians. A 72-year-old man was referred to our hospital for definitive treatment of known MAC from previous biopsy. Read More

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http://dx.doi.org/10.1097/SCS.0000000000003119DOI Listing
November 2016
17 Reads

Mohs micrographic surgery of rare cutaneous tumours.

J Eur Acad Dermatol Venereol 2017 Aug 24;31(8):1285-1288. Epub 2017 Jan 24.

Department of Dermatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

Background: Recurrence rates after Mohs micrographic surgery (MMS) for rare cutaneous tumours are poorly defined.

Objective: To investigate the recurrence rate after MMS for rare cutaneous tumours at a university centre.

Methods & Materials: Retrospective review of all rare cutaneous tumours treated with MMS at a large university centre between January 2008 and December 2012. Read More

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http://dx.doi.org/10.1111/jdv.14079DOI Listing
August 2017
11 Reads

Histopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology.

Wien Med Wochenschr 2018 Jun 10;168(9-10):218-227. Epub 2016 Nov 10.

Centro Studi per la Ricerca Multidisciplinare e Rigenerativa, Università Degli Studi "G. Marconi", Rome, Italy.

Mohs micrographic surgery is a specialized subset of staged surgical excisions with each subsequent stage being driven largely by the histologic findings of the previous stage. Therefore, it is imperative that histologic analysis is performed in an accurate manner. Frozen section and tissue flattening is a crucial step in Mohs surgery. Read More

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http://dx.doi.org/10.1007/s10354-016-0528-0DOI Listing
June 2018
17 Reads

Sclerosing Microcystic Adenocarcinoma of the Head and Neck Mucosa: A Neoplasm Closely Resembling Microcystic Adnexal Carcinoma.

Head Neck Pathol 2016 Dec 27;10(4):501-508. Epub 2016 May 27.

Department of Pathology, University of Virginia, Charlottesville, VA, USA.

Microcystic adnexal carcinoma (MAC) occurs predominantly in the centrofacial skin and has been only rarely reported in mucosal surfaces. We here present a 5 case series of tumors closely resembling MAC occurring in the mucosal surfaces of the head and neck, which we have termed sclerosing microcystic adenocarcinomas. These tumors showed a predilection for women (4:1) with an average patient age of 52. Read More

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http://dx.doi.org/10.1007/s12105-016-0731-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082055PMC
December 2016
19 Reads

Primary Cutaneous Mammary Analog Secretory Carcinoma With ETV6-NTRK3 Translocation.

Am J Dermatopathol 2016 Nov;38(11):842-845

Departments of *Dermatology, and †Pathology, Northwestern University, Chicago, IL; and ‡Forefront Dermatology, Manitowoc, WI.

Mammary analog secretory carcinoma (MASC) is a recently described tumor of the salivary glands named for its morphological and molecular similarity to secretory carcinoma of the breast. Many primary carcinomas arising from the adnexal glands also share similar morphology to those arising from the breast. Brandt et al first described primary cutaneous MASC in 2009 and since then only 2 other cases have been reported. Read More

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http://dx.doi.org/10.1097/DAD.0000000000000590DOI Listing
November 2016
9 Reads

Microcystic Adnexal Vulvar Carcinoma: A Case Report.

J Low Genit Tract Dis 2017 Jan;21(1):e5-e7

Gynecology Department and Pathology Department, Hospital Italiano of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1097/LGT.0000000000000269DOI Listing
January 2017
11 Reads

Diagnosis of pigmented microcystic adnexal carcinoma.

G Ital Dermatol Venereol 2016 Oct;151(5):564-5

Department of Dermatology, Southwest Hospital of Third Military Medical University, Chongqing, China -

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October 2016
8 Reads

Microcystic adnexal carcinoma in a non-Caucasian patient: A case report and review of the literature.

Oncol Lett 2016 Apr 17;11(4):2471-2474. Epub 2016 Feb 17.

Department of Oral and Maxillofacial Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

Microcystic adnexal carcinoma (MAC) is extremely rare among Asians, with the majority of cases presenting in Caucasian individuals. The current study describes the case of a 38-year-old Chinese woman who presented with a 10 year history of a mass in the upper lip. A biopsy resulted in a diagnosis of MAC. Read More

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http://dx.doi.org/10.3892/ol.2016.4242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812535PMC
April 2016
22 Reads
0.990 Impact Factor

Underutilization of Mohs Micrographic Surgery for Less Common Cutaneous Malignancies in the United States.

Dermatol Surg 2016 May;42(5):653-62

*Department of Medicine, Section of Dermatology, West Virginia University, Morgantown, West Virginia; †University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ‡Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania; §Department of Epidemiology, Epidemiology Data Center, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

Background: Consensus guidelines have defined select less common skin cancers appropriate for Mohs micrographic surgery (MMS), as these tumors are characterized by asymmetric growth patterns that challenge conventional surgical extirpation of disease.

Objective: The authors aimed to define surgical patterns of care and to identify factors affecting treatment selection in the United States.

Materials And Methods: Retrospective cohort analysis of nonmetastatic nonmelanoma skin cancers deemed appropriate for MMS by American Academy of Dermatology/American College of Mohs Surgery/American Society for Dermatologic Surgery Association/American Society for Mohs Surgery appropriate use criteria from the National Cancer Data Base from 1998 to 2012. Read More

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http://dx.doi.org/10.1097/DSS.0000000000000705DOI Listing
May 2016
60 Reads

Morpheaform Basal Cell Carcinomas With Areas of Predominantly Single-Cell Pattern of Infiltration: Diagnostic Utility of p63 and Cytokeratin.

Am J Dermatopathol 2016 Oct;38(10):744-50

Departments of *Pathology and †Dermatology, University of Michigan Health System, Ann Arbor MI; ‡Michigan Center for Translational Pathology, University of Michigan Health System, Ann Arbor MI; and §Department of Urology, Vattikutti Urology Institute, Henry Ford Health System, Detroit, MI.

Background: Morpheaform basal cell carcinoma (BCC) is a variant of BCC characterized by narrow strands and nests of basaloid cells with dense sclerotic stroma. The histologic extent often exceeds the clinical impression, leading to high recurrence rates after standard excision. The authors encountered a case with single-cell invasion distant from the main tumor. Read More

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http://dx.doi.org/10.1097/DAD.0000000000000541DOI Listing
October 2016
14 Reads

Epidemiology and Prognosis of Primary Periocular Sweat Gland Carcinomas.

Ophthalmic Plast Reconstr Surg 2017 Mar/Apr;33(2):101-105

*Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa; †Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery, and ‡Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, U.S.A.

Purpose: To characterize the clinical presentation, management, and outcomes of patients with sweat gland carcinoma of the periocular region. To review the pathologic classification scheme, compare the clinical behavior between subtypes, and discuss treatment recommendations for periocular sweat gland carcinomas.

Methods: Retrospective study from 2 tertiary centers, which are part of the American Society of Ophthalmic Plastic and Reconstructive Surgery Oncology Database. Read More

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http://dx.doi.org/10.1097/IOP.0000000000000658DOI Listing
March 2017
14 Reads

Infundibulocystic Structures and Prominent Squamous Metaplasia in Sebaceoma-A Rare Feature. A Clinicopathologic Study of 10 Cases.

Am J Dermatopathol 2016 Sep;38(9):678-82

*Labor für Dermatohistologie und Oralpathologie, München, Germany; †Dermatopathologie Friedrichshafen, Friedrichshafen, Germany; ‡Miraca Life Science Laboratory, Irving, TX; §Department of Clinical Pathology, University of Zagreb, Zagreb, Croatia; ¶Department of Pathology, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic; ‖Bioptical Laboratory, Pilsen, Czech Republic; and **Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.

The authors describe 10 cases of sebaceoma that manifested prominent infundibulocystic structures in all cases and, additionally, conspicuous squamous metaplasia in 6 neoplasms. All tumors occurred on the scalp or the face (2 cases lacked clinical information) and presented as a solitary lesion, measuring from 5 to 20 mm. The patients' age ranged from 22 to 89 years. Read More

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http://dx.doi.org/10.1097/DAD.0000000000000494DOI Listing
September 2016
16 Reads

Microcystic Adnexal Carcinoma of the scalp in an african-american male.

Dermatol Online J 2016 Sep 15;22(9). Epub 2016 Sep 15.

University of Texas Southwestern Medical Center.

Microcystic adnexal carcinoma (MAC) is a rare adnexal neoplasm that typically presents in Caucasians. We report a rare case of MAC in a 68 year old African American male that presented as a large asymptomatic scalp mass. The clinical and histologic features of MAC are discussed. Read More

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September 2016
7 Reads

Misdiagnosed microcystic adnexal carcinoma on the lateral forehead and challenges in reconstruction of a large and bone-deep defect.

J Dtsch Dermatol Ges 2016 Jan;14(1):86-90

Department of Dermatology, Venereology and Allergology, Academic Teaching Department of Medical University Innsbruck, Central Teaching Hospital Bolzano/Bozen, Italy.

Background: Microcystic adnexal carcinoma (MAC) is a rare cutaneous malignancy characterized by aggressive local infiltration, including a high propensity for perineural invasion. Histologically it can be easily confused with benign adnexal tumors, which often leads to inappropriate initial treatment. As a consequence delayed surgical excision often requires removal of large cutaneous masses which can be followed by challenges in reconstruction. Read More

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http://dx.doi.org/10.1111/ddg.12867DOI Listing
January 2016
24 Reads
1.820 Impact Factor