7,210,889 results match your criteria Methods in molecular biology Clifton N.J.[Journal]

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Improved survival of glioblastoma patients treated at academic and high-volume facilities: a hospital-based study from the National Cancer Database.

J Neurosurg 2019 Feb 15:1-12. Epub 2019 Feb 15.

1The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston McGovern Medical School.

OBJECTIVEThe present study was designed to explore the association between facility type (academic center [AC] vs non-AC), facility volume (high-volume facility [HVF] vs low-volume facility [LVF]), and outcomes of glioblastoma (GBM) treatment.METHODSBased on the National Cancer Database (NCDB), GBM patients were categorized by treatment facility type (non-AC vs AC) and volume [4 categories (G1-G4): < 5.0, 5. Read More

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http://dx.doi.org/10.3171/2018.10.JNS182247DOI Listing
February 2019

Somatotopic organization of the human spinothalamic tract: in vivo computed tomography-guided mapping in awake patients undergoing cordotomy.

J Neurosurg Spine 2019 Feb 15:1-7. Epub 2019 Feb 15.

3Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.

OBJECTIVEThe location of the human spinothalamic tract (STT) in the anterolateral spinal cord has been known for more than a century. The exact nature of the neuronal fiber lamination within the STT, however, remains controversial. After correlating in vivo macrostimulation-induced pain/temperature sensation during percutaneous cervical cordotomy with simultaneous CT imaging of the electrode tip location, the authors present a modern description of the somatotopy of the human cervical STT. Read More

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http://dx.doi.org/10.3171/2018.11.SPINE18172DOI Listing
February 2019

Accelerated transcranial magnetic stimulation for the treatment of Patients with depression: A review.

Authors:
Fady Rachid

Asian J Psychiatr 2019 Feb 8;40:71-75. Epub 2019 Feb 8.

Private Practice, 7, place de la Fusterie, 1204, Geneva, Switzerland. Electronic address:

Major depressive disorder is a highly prevalent and profoundly disabling psychiatric disorder with significant morbidity and mortality and it is very often resistant to antidepressants, electroconvulsive therapy and psychotherapy. Therapeutic alternatives include repetitive transcranial magnetic stimulation which may be an effective choice for treatment-resistant depression but requires prolonged treatments for at least four to six weeks. Shorter exposure to this technique might be more advantageous for certain cases. Read More

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http://dx.doi.org/10.1016/j.ajp.2019.02.003DOI Listing
February 2019

Changes in blood pressure associated with lead, manganese, and selenium in a Bangladeshi cohort.

Environ Pollut 2019 Feb 7;248:28-35. Epub 2019 Feb 7.

Division of Epidemiology and Biostatistics, University of Illinois at Chicago, School of Public Health, Chicago, IL, USA. Electronic address:

Background: Heavy metal contamination is widespread in Bangladesh. Previous studies have observed lead increases blood pressure over time. However, the role of other metal contaminants and essential micronutrients, which could also adversely affect blood pressure or act as protective factors, is understudied. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.01.129DOI Listing
February 2019

Adjuvant androgen deprivation therapy for poor-risk, androgen receptor-positive salivary duct carcinoma.

Eur J Cancer 2019 Feb 13;110:62-70. Epub 2019 Feb 13.

Department of Medical Oncology, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, the Netherlands. Electronic address:

Aim: Salivary duct carcinoma (SDC), an aggressive subtype of salivary gland cancer, is androgen receptor (AR)-positive in 67-96% of cases. In patients with locally recurrent and metastatic (R/M) AR-positive SDC, androgen deprivation therapy (ADT) has an overall response rate of 18-64.7%. Read More

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http://dx.doi.org/10.1016/j.ejca.2018.12.035DOI Listing
February 2019

A randomized, double-blind, placebo-controlled trial to assess the efficAcy and safety of Trimetazidine in patients with angina pectoris having been treated by percutaneous coronary intervention (ATPCI study): Rationale, design, and baseline characteristics.

Am Heart J 2019 Jan 15;210:98-107. Epub 2019 Jan 15.

Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou (HEGP), Department of Cardiology, Paris, France; Université Paris-Descartes, Paris, France; INSERM U-970, Paris, France.

Background: About 30% of angina patients have persisting symptoms despite successful revascularization and antianginal therapy. Moreover, in stable patients, percutaneous coronary intervention (PCI) does not improve survival as compared with medical therapy alone. Trimetazidine, an antianginal agent devoid of hemodynamic effect, may help reducing symptoms and improving outcomes after PCI. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00028703193000
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http://dx.doi.org/10.1016/j.ahj.2018.12.015DOI Listing
January 2019
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Marital quality, partner's engagement and continuous positive airway pressure adherence in obstructive sleep apnea.

Sleep Med 2018 Dec 26;55:56-61. Epub 2018 Dec 26.

HP2 Laboratory, INSERM U1042, Univ. Grenoble Alpes, Grenoble, France; EFCR Laboratory, Grenoble Alpes University Hospital, Grenoble, France. Electronic address:

Background: Continuous positive airway pressure (CPAP) is the first line therapy for obstructive sleep apnea (OSA) but its effectiveness requires high adherence. We aimed to assess the impacts of the spouse's/partner's involvement and the quality of the couple's relationship on CPAP adherence.

Methods: In a multicenter prospective study conducted in France, patients reported their subjective views regarding their partner's engagement in their CPAP treatment and the quality of their marital relationship using the Quality of Marriage Index. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.12.009DOI Listing
December 2018

Split-belt treadmill walking in patients with Parkinson's disease: A systematic review.

Gait Posture 2019 Feb 7;69:187-194. Epub 2019 Feb 7.

Department of Neurology, University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.

Background: Walking on a split-belt treadmill (SBT) can help to modulate an asymmetric gait, particularly for people with neurological conditions, such as Parkinson's disease (PD), where asymmetry plays a role due to the laterality of the disease.

Research Question: This systematic review critically evaluates the literature on SBT in PD. First, different SBT paradigms and methodological approaches were evaluated. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.01.032DOI Listing
February 2019

Assessment of alternative methods for analyzing X-ray fluorescence spectra.

Appl Radiat Isot 2019 Feb 1;146:133-138. Epub 2019 Feb 1.

Physics Department, Mount Allison University, 67 York Street, Sackville, New Brunswick, Canada. Electronic address:

When analyzing characteristic peaks in X-ray fluorescence (XRF) spectra, the peak area is the value most often used to quantify peak size. However, some studies have reported the amplitude of the peak instead of the area. When the width of the peak is allowed to vary from trial to trial in order to provide the best possible fit to the data, these two alternative methods can yield slightly different results. Read More

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http://dx.doi.org/10.1016/j.apradiso.2019.01.033DOI Listing
February 2019

Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy.

Clin Neurophysiol 2019 Jan 31;130(4):491-504. Epub 2019 Jan 31.

Laboratory of Children's Brain Dynamics, Division of Newborn Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Fetal-Neonatal Neuroimaging Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

Objective: To evaluate the accuracy and clinical utility of conventional 21-channel EEG (conv-EEG), 72-channel high-density EEG (HD-EEG) and 306-channel MEG in localizing interictal epileptiform discharges (IEDs).

Methods: Twenty-four children who underwent epilepsy surgery were studied. IEDs on conv-EEG, HD-EEG, MEG and intracranial EEG (iEEG) were localized using equivalent current dipoles and dynamical statistical parametric mapping (dSPM). Read More

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http://dx.doi.org/10.1016/j.clinph.2019.01.009DOI Listing
January 2019

Impaired prefrontal cortex-thalamus pathway in intractable temporal lobe epilepsy with aberrant executive control function: MRI evidence.

Clin Neurophysiol 2019 Jan 18;130(4):484-490. Epub 2019 Jan 18.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, PR China; Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, PR China. Electronic address:

Objectives: This study aimed to assess structural and functional connectivity alterations of the prefrontal cortex (PFC)-thalamus axis in individuals with unilateral intractable temporal lobe epilepsy (TLE) showing executive control function (ECF) impairment and to explore the potential mechanism.

Methods: Thirty-eight individuals with intractable left TLE and twenty-nine healthy controls (HCs) were recruited for diffusion tensor imaging (DTI) and resting-state fMRI (rs-fMRI) scanning. According to the ECF state, patients were assigned to normal and impaired ECF groups. Read More

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http://dx.doi.org/10.1016/j.clinph.2018.12.007DOI Listing
January 2019

Prolonged cortical silent period is related to poor fitness and fatigue, but not tumor necrosis factor, in Multiple Sclerosis.

Clin Neurophysiol 2019 Feb 4;130(4):474-483. Epub 2019 Feb 4.

Recovery and Performance Laboratory, Faculty of Medicine, L.A. Miller Centre, Memorial University of Newfoundland, St. John's, NL, Canada. Electronic address:

Objective: Poor fitness among people with Multiple Sclerosis (MS) aggravates disease symptoms. Whether low fitness levels accompany brain functioning changes is unknown.

Methods: MS patients (n = 82) completed a graded maximal exercise test, blood was drawn, and transcranial magnetic stimulation determined resting and active motor thresholds, motor evoked potential latency, and cortical silent period (CSP). Read More

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http://dx.doi.org/10.1016/j.clinph.2018.12.015DOI Listing
February 2019

Subthalamic and pallidal oscillatory activity in patients with Neurodegeneration with Brain Iron Accumulation type I (NBIA-I).

Clin Neurophysiol 2019 Jan 25;130(4):469-473. Epub 2019 Jan 25.

Department of Neurology, Charité - Universitätsmedizin Berlin, Germany; NeuroCure, ExzellenzCluster, Charité - Universitätsmedizin Berlin, Germany; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Germany. Electronic address:

Objectives: Neurodegeneration with Brain Iron Accumulation type I (NBIA-I) is a rare hereditary neurodegenerative disorder with pallidal degeneration leading to disabling generalized dystonia and parkinsonism. Pallidal or subthalamic deep brain stimulation can partially alleviate motor symptoms. Disease-specific patterns of abnormally enhanced oscillatory neuronal activity recorded from the basal ganglia have been described in patients with movement disorders undergoing deep brain stimulation (DBS). Read More

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http://dx.doi.org/10.1016/j.clinph.2018.12.012DOI Listing
January 2019

Differences between flexion and extension synergy-driven coupling at the elbow, wrist, and fingers of individuals with chronic hemiparetic stroke.

Clin Neurophysiol 2019 Jan 31;130(4):454-468. Epub 2019 Jan 31.

Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, USA; Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address:

Objective: The flexion and extension synergies were quantified at the paretic elbow, forearm, wrist, and finger joints within the same group of participants for the first time. Differences in synergy expression at each of the four joints were examined, as were the ways these differences varied across the joints.

Methods: Twelve post-stroke individuals with chronic moderate-to-severe hemiparesis and six age-matched controls participated. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.01.010DOI Listing
January 2019

Economic sanctions threaten population health: the case of Iran.

Public Health 2019 Feb 13;169:10-13. Epub 2019 Feb 13.

Department of Finance, NEOMA Business School, France.

Objective: The aim of the study is to review evidence of the negative consequences of international economic sanctions on population health in Iran and pathways via which the sanctions affect health.

Study Design: This is a narrative review.

Methods: Data from the World Bank and the Central Bank of Iran were gathered to clarify economic consequences of sanctions. Read More

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http://dx.doi.org/10.1016/j.puhe.2019.01.006DOI Listing
February 2019

Exploring socio-economic inequalities in the use of medicines: is the relation mediated by health status?

Public Health 2019 Feb 13;169:1-9. Epub 2019 Feb 13.

LMU Munich, University Hospital, Department of Psychiatry and Psychotherapy, Nußbaumstr. 7, 80336 Munich, Germany. Electronic address:

Objectives: This study evaluated mediating effects of the health status on the association between socio-economic status (SES) and medicine use. It was hypothesized that more privileged people show a reduced use of medicines, as compared with the underprivileged, because of their superior health status. It was further hypothesized that people may apply medication based on their type of health complaint (ill physical versus mental status). Read More

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http://dx.doi.org/10.1016/j.puhe.2018.12.018DOI Listing
February 2019

Iterative fully convolutional neural networks for automatic vertebra segmentation and identification.

Med Image Anal 2019 Feb 12;53:142-155. Epub 2019 Feb 12.

Image Sciences Institute, University Medical Center Utrecht, Room Q.02.4.45, 3508 GA Utrecht, P.O. Box 85500, The Netherlands.

Precise segmentation and anatomical identification of the vertebrae provides the basis for automatic analysis of the spine, such as detection of vertebral compression fractures or other abnormalities. Most dedicated spine CT and MR scans as well as scans of the chest, abdomen or neck cover only part of the spine. Segmentation and identification should therefore not rely on the visibility of certain vertebrae or a certain number of vertebrae. Read More

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http://dx.doi.org/10.1016/j.media.2019.02.005DOI Listing
February 2019

Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage?

Psychoneuroendocrinology 2019 Feb 7;103:276-283. Epub 2019 Feb 7.

University of Groningen, University Medical Center Groningen, Department of Psychiatry, University of Groningen PO Box 72, 9700 AB, Groningen, the Netherlands.

Background: Brain-derived neurotrophic factor (BDNF) levels decline during depression and normalise after remission, although studies in older patient samples are inconsistent. Whether BDNF serum levels predict depression remission is unclear. We hypothesize that the predictive value of serum BDNF levels in late-life depression is moderated by selective serotonin reuptake inhibitors (SSRI) usage and early traumatization. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2019.02.003DOI Listing
February 2019

Data fitting approach more critical than exposure scenarios and treatment of censored data for quantitative microbial risk assessment.

Water Res 2019 Feb 4;154:45-53. Epub 2019 Feb 4.

Instituto de Investigaciones para la Industria Química (INIQUI), CONICET, Universidad Nacional de Salta (UNSa), Av. Bolivia 5150, Salta, 4400, Argentina; Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, 637551, Singapore; Facultad de Ingeniería, UNSa, Salta, Argentina. Electronic address:

Recreational waters are a source of many diseases caused by human viral pathogens, including norovirus genogroup II (NoV GII) and enterovirus (EV). Water samples from the Arenales river in Salta, Argentina, were concentrated by ultrafiltration and analyzed for the concentrations of NoV GII and EV by quantitative PCR. Out of 65 samples, 61 and 59 were non-detects (below the Sample Limit of Detection limit, SLOD) for EV and NoV GII, respectively. Read More

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http://dx.doi.org/10.1016/j.watres.2019.01.041DOI Listing
February 2019

Probing deoxysugar conformational preference: A comprehensive computational study investigating the effects of deoxygenation.

Carbohydr Res 2018 Dec 12;475:17-26. Epub 2018 Dec 12.

Department of Chemistry, Indiana University, Bloomington, IN, 47405, USA. Electronic address:

Deoxysugars are intrinsic components in a number of antibiotics, antimicrobials, and therapeutic agents that often dictate receptor binding, improve efficacy, and provide a diverse toolbox in modifying glycoconjugate function due to an extensive number of unique isomers and inherent conformational flexibility. Hence, this work provides a comprehensive examination of the conformational effects associated with deoxygenation of the pyranose ring. Both the location and degree of deoxygenation were evaluated by interrogating the energetic landscape for a number of mono- and dideoxyhexopyranose derivatives using DFT methods (M05-2X/cc-pVTZ(-f)). Read More

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http://dx.doi.org/10.1016/j.carres.2018.12.003DOI Listing
December 2018

Temporal and geographical variations in colorectal cancer incidence in Northern Iran 2004-2013.

Cancer Epidemiol 2019 Feb 13;59:143-147. Epub 2019 Feb 13.

Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Genetic Epidemiology Group, Folkhälsan Research Center, Faculty of Medicine, Helsinki University, Helsinki, Finland; Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.

Introduction: Colorectal cancer (CRC) is one of the most common cancers in the Golestan province, Northern Iran. The purpose of this study is to describe colorectal cancer incidence patterns and trends in the province 2004-2013.

Methods: Data on CRC cases were obtained from the Golestan Population-based Cancer Registry (GPCR). Read More

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http://dx.doi.org/10.1016/j.canep.2019.02.003DOI Listing
February 2019

Contemporary trends of pelvic lymph node dissection at radical cystectomy for urothelial carcinoma of urinary bladder and associated cancer specific mortality and complications: comparison between octogenarian versus younger patients.

Cancer Epidemiol 2019 Feb 13;59:135-142. Epub 2019 Feb 13.

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Québec, Canada; Division of Urology, University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada.

Background: We analysed contemporary pelvic lymph node dissection (PLND) trend during radical cystectomy (RC) for urothelial carcinoma of urinary bladder (UCUB), as well as PLND association with cancer specific mortality (CSM) and complications after stratification according to octogenarian vs. younger age.

Materials And Methods: Within the SEER and NIS databases, respectively 10,427 (T2 and T3 stages) and 19,203 (all T-stages) RC patients (2004-2015) for UCUB were identified. Read More

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http://dx.doi.org/10.1016/j.canep.2019.02.002DOI Listing
February 2019

Force-induced decline of TEA domain family member 1 contributes to osteoclastogenesis via regulation of Osteoprotegerin.

Arch Oral Biol 2019 Jan 31;100:23-32. Epub 2019 Jan 31.

Department of Orthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, China. Electronic address:

Objective: This study aims to investigate the responsiveness of transcription factor TEA domain family member 1 (TEAD1) to mechanical force and its impact on osteoclastogenesis as well as expression of Osteoprotegerin (OPG), an inhibitor for osteoclastogenesis playing crucial roles in mechanical stress-induced bone remodeling and orthodontic tooth movement (OTM).

Methods: We first analyzed the correlation between several transcription factors and OPG expression in human periodontal ligament cells (PDLCs). Then dynamic expression changes of TEAD1 with force application were analyzed due to its high correlation with OPG. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2019.01.020DOI Listing
January 2019

Worldwide variation in Pseudomonas associated ventilator associated pneumonia. A meta-regression.

Authors:
James C Hurley

J Crit Care 2019 Feb 6;51:88-93. Epub 2019 Feb 6.

Department of Rural Health, Melbourne Medical School, University of Melbourne, Internal Medicine Service, Ballarat Health Services, Victoria, Australia. Electronic address:

Purpose: The objective here is to define the extent and possible reasons for geographic variation in Pseudomonas aeruginosa associated with Ventilator Associated Pneumonia (VAP).

Methods: A random effects meta-regression model of Pseudomonas associated VAP incidence within the published literature was undertaken incorporating group level factors such trauma admission, year of publication and use of bronchoscopic sampling towards VAP diagnosis.

Results: Pseudomonas associated VAP incidence was reported in 162 studies from seven worldwide regions published over 30 years. Read More

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http://dx.doi.org/10.1016/j.jcrc.2019.02.001DOI Listing
February 2019

ICU readmission of patients with cancer: Incidence, risk factors and mortality.

J Crit Care 2019 Feb 7;51:84-87. Epub 2019 Feb 7.

Department of Medicine, Section of Pulmonary and Critical Care, King Hussein Cancer Center, Jordan. Electronic address:

Purpose: Few studies evaluated ICU readmission in cancer patients. This study aimed to describe the incidence and risk factors for ICU readmission in cancer patients and the association with mortality.

Materials And Methods: A retrospective cohort study at a comprehensive cancer center, which included cancer patients who were discharged after their initial ICU admission over a 5-year period. Read More

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http://dx.doi.org/10.1016/j.jcrc.2019.02.008DOI Listing
February 2019

Dynamic Histological Events and Molecular Changes in Excisional Wound Healing of Diabetic DB/DB Mice.

J Surg Res 2019 Feb 13;238:186-197. Epub 2019 Feb 13.

Department of Plastic Surgery, Rhode Island Hospital, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island.

Background: Wound contraction and re-epithelialization over the entire healing process had never been histologically examined daily in diabetic mouse wounds. Correlating morphological characters with molecular changes may be essential to understand the potential mechanism of impeded diabetic wound healing.

Materials And Methods: In 99 db/db and 63 db/m mice, dorsal-paired 8 mm-diameter wounds were created. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.048DOI Listing
February 2019

Unfractionated Heparin Alleviates Sepsis-Induced Acute Lung Injury by Protecting Tight Junctions.

J Surg Res 2019 Feb 13;238:175-185. Epub 2019 Feb 13.

Department of Critical Care Medicine, The First Affiliated Hospital, China Medical University, Shenyang, People's Republic of China. Electronic address:

Background: Unfractionated heparin (UFH) has been shown to ameliorate lung edema and lung vascular leakage in lipopolysaccharide-induced lung injury. Impaired tight junction (TJ) function is a sign of sepsis-induced acute respiratory distress syndrome (ARDS) and acute lung injury (ALI), which is closely related to the downregulated expression of TJ-specific proteins or the upregulated expression of inflammatory cytokines. Because UFH has been intensively studied in modulating inflammation, we hypothesize that UFH may play a positive role in treating sepsis-induced ARDS/ALI by protecting TJs. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.020DOI Listing
February 2019

Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial).

J Surg Res 2019 Feb 13;238:164-174. Epub 2019 Feb 13.

Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, San Francisco, California. Electronic address:

Background: N-3 polyunsaturated fatty acid (PUFA) supplementation has been associated with reduced mortality and inflammation in patients with cardiovascular disease. There are limited data on the effects of n-3 PUFA supplementation in patients with peripheral artery disease (PAD).

Materials And Methods: The OMEGA-PAD II trial was a double-blinded, randomized, placebo-controlled trial to assess the effect of 3 mo of high-dose oral n-3 PUFA supplementation on inflammation, endothelial function, and walking ability in patients with PAD. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.038DOI Listing
February 2019

Intrahepatic Delivery of Pegylated Catalase Is Protective in a Rat Ischemia/Reperfusion Injury Model.

J Surg Res 2019 Feb 13;238:152-163. Epub 2019 Feb 13.

The COPPER Laboratory, The Ohio State University Wexner Medical Center, Columbus, Ohio; Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:

Background: Ischemia/reperfusion injury (IRI) can occur during liver surgery. Endogenous catalase is important to cellular antioxidant defenses and is critical to IRI prevention. Pegylation of catalase (PEG-CAT) improves its therapeutic potential by extending plasma half-life, but systemic administration of exogenous PEG-CAT has been only mildly therapeutic for hepatic IRI. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.028DOI Listing
February 2019

Prospective Clinical Trial Comparing Trapezial Denervation With Trapeziectomy for the Surgical Treatment of Arthritis at the Base of the Thumb.

J Surg Res 2019 Feb 13;238:144-151. Epub 2019 Feb 13.

The Pulvertaft Hand Surgery Centre, Royal Derby Hospital, Derby, United Kingdom.

Background: Trapeziectomy is considered to be the "gold standard" procedure for first carpometacarpal joint (first CMCJ) osteoarthritis. First CMCJ denervation offers the potential benefit of a shorter procedure with bone and joint preservation and swift postoperative rehabilitation. This trial aimed to compare functional outcomes, patient satisfaction, quality of life, and cost effectiveness following these treatments. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.011DOI Listing
February 2019

Factors Influencing Colon and Rectal Surgery Residency Program Selection.

J Surg Res 2019 Feb 13;238:137-143. Epub 2019 Feb 13.

Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota.

Background: Little information exists to help colon and rectal surgery residency programs determine which factors applicants find important when selecting a training program. Our aim was to identify factors applicants find pertinent in the selection of their desired colon and rectal surgery residency program.

Methods: After the 2016 and 2017 National Resident Matching Program (The Match), a 58-question anonymous web-based survey was sent to all trainees who applied to our colon and rectal surgery residency program to determine factors applicants find important in selecting colon and rectal surgery residency training programs. Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.042DOI Listing
February 2019

SELDI-TOF MS Analysis of Hepatocellular Carcinoma in an Australian Cohort.

J Surg Res 2019 Feb 13;238:127-136. Epub 2019 Feb 13.

Cancer Surgery and Metabolism Research Group, University of Sydney, Kolling Institute of Medical Research, St Leonards, NSW, Australia; Upper GI Surgical Unit, Royal North Shore Hospital and North Shore Private Hospital, St Leonards, NSW, Australia; Discipline of Surgery, The University of Sydney, Camperdown, NSW, Australia.

Background: Hepatocellular carcinoma (HCC) is a common cause of cancer death worldwide. Resection offers the best chance of long-term survival, but a consistent adverse prognostic factor is the presence of microvascular invasion (MVI). In this study, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS), a high throughput method of analyzing complex samples, was used to explore differentially expressed proteins between HCC and adjacent nontumour liver tissue (ANLT). Read More

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http://dx.doi.org/10.1016/j.jss.2019.01.008DOI Listing
February 2019

Perpetration of sexual aggression among adolescents in South Africa.

J Adolesc 2019 Feb 13;72:32-36. Epub 2019 Feb 13.

Department of Psychiatry and Mental Health, Alpert Medical School of Brown University; Providence/Boston Center for AIDS Research, USA.

Introduction: In South Africa, one in three men have reported perpetrating rape. Adolescence presents a unique developmental period for primary prevention of violence. However, few studies characterize the epidemiology of sexual violence among adolescents in South Africa. Read More

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http://dx.doi.org/10.1016/j.adolescence.2019.02.002DOI Listing
February 2019

Adolescent men's attitudes and decision making in relation to pregnancy and pregnancy outcomes: An integrative review of the literature from 2010 to 2017.

J Adolesc 2019 Feb 12;72:23-31. Epub 2019 Feb 12.

Queen's University Belfast, School of Nursing and Midwifery, 97 Lisburn Rd, Belfast, BT9 7BL, UK. Electronic address:

Introduction: The review updates a previous review conducted in 2010 (Lohan et al.), summarizing the available literature on young men's attitudes and decision-making in the context of addressing two questions: (1) What are adolescent men's attitudes to adolescent pregnancy? (2) What are adolescent men's attitudes and decision-making in relation to pregnancy outcomes?

Methods: Using Whittemore and Knafl's process for conducting an integrative review, 38 studies published between 2010 and 2017 reporting on young men's attitudes and decision-making in relation to pregnancy and pregnancy outcomes were analysed.

Results: One of the most important conclusions of this review is that the findings of studies can often be contradictory. Read More

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http://dx.doi.org/10.1016/j.adolescence.2018.12.008DOI Listing
February 2019

Responses of wheat (Triticum aestivum) plants grown in a Cd contaminated soil to the application of iron oxide nanoparticles.

Ecotoxicol Environ Saf 2019 Feb 13;173:156-164. Epub 2019 Feb 13.

Soil, and Groundwater-Management, Institute for Soil Engineering, Water and Wastewater Management, University of Wuppertal, Pauluskirchstraße 7, Wuppertal, Germany; Department of Environment and Energy, Sejong University, Seoul 05006, Republic of Korea.

The present study demonstrated the possible impacts of iron oxide nanoparticles (Fe NPs) on the alleviation of toxic effects of cadmium (Cd) in wheat and enhance its growth, yield, and Fe biofortification. A pot experiment was conducted in historically Cd-contaminated soil using five levels of Fe NPs (0, 5, 10, 15, and 20 ppm) by soil and foliar application methods. The plants were harvested after 125 days of growth while vegetative parameters, antioxidant capacity, electrolyte leakage (EL) in leaves as well as Cd, and Fe concentrations in wheat grains, roots, and shoots were measured. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.01.118DOI Listing
February 2019
2.762 Impact Factor

Utility of Likert scale (Deauville criteria) in assessment of Chemoradiotherapy response of primary oropharyngeal squamous cell Cancer site.

Clin Imaging 2019 Jan 16;55:89-94. Epub 2019 Jan 16.

Department of Radiology, Division of Nuclear Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA. Electronic address:

Introduction: The aim of this study is to determine whether Likert scale (Deauville criteria) can be used to classify oropharyngeal squamous cell cancer (OPSCC) patients as 'responders' and 'nonresponders' by utilizing FDG-PET/CT for primary tumor site. The second aim is to compare the performance of methods used in interpretation of posttreatment PET/CT scans (Likert scale, SUVmax, ratios of SUVmax primary lesion to mediastinum 'SUVmax P/M' and SUVmax primary lesion to liver 'SUVmax P/L') in predicting treatment response.

Methods: Seventy-seven PET/CT scans were assessed by Deauville criteria, five-point Likert scale. Read More

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http://dx.doi.org/10.1016/j.clinimag.2019.01.007DOI Listing
January 2019

Depression is associated with diabetes status of family members: NHANES (1999-2016).

J Affect Disord 2019 Feb 6;249:121-126. Epub 2019 Feb 6.

School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China. Electronic address:

Background: The majority of the studies in this area focus on the psychological impact of having diabetic children or adolescents on parents, while a limited number of studies have investigated the effect of diabetes on the mental health status of family members in the general population. Thus, the aim of the current study is to explore the possible association between mental health disorders (depression, anxiety and panic) and diabetes status of family members among a national sample of adults in the United States.

Methods: Our analysis included 1,787 and 25,574 participants in the National Health and Nutrition Examination Survey (NHANES) 1999-2004 and 2005-2016, respectively. Read More

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http://dx.doi.org/10.1016/j.jad.2019.02.019DOI Listing
February 2019

Tuberculosis screening for prospective migrants to high-income countries: systematic review of policies.

Public Health 2019 Feb 13;168:142-147. Epub 2019 Feb 13.

King's College London, School of Population Health and Environmental Sciences, London, UK.

Objective: To compare predeparture tuberculosis (TB) screening policies, including screening criteria and screening tests, and visa requirements for prospective migrants to high-income countries that have low to intermediate TB incidence and high immigration.

Study Design: Systematic review of policy documents.

Methods: We systematically identified high-income, high net-migration countries with an estimated TB incidence of <30 per 100,000. Read More

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http://dx.doi.org/10.1016/j.puhe.2018.12.016DOI Listing
February 2019

Comparison of TSNAs concentration in saliva according to type of tobacco smoked.

Environ Res 2018 Dec 6;172:73-80. Epub 2018 Dec 6.

Group of Evaluation of Health Determinants and Health Policies, Department of Basic Sciences, Universitat Internacional de Catalunya, Carrer de Josep Trueta s/n, 08195 Sant Cugat del Vallès, Barcelona, Spain; Tobacco Control Unit, Cancer Prevention and Control Program, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain; Cancer Prevention and Control Group, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain. Electronic address:

Objective: To compare tobacco-specific nitrosamines (TSNAs) measured in saliva according to different types of tobacco smoked in a sample of smokers of the city of Barcelona (Spain).

Methods: We used data from a cross-sectional study of a sample of the adult smoking population of Barcelona, Spain in 2013-2014 (n = 165). We classified smokers in five groups according to the type of tobacco smoked: a) manufactured cigarettes only, b) roll-your-own (RYO) cigarettes only, c) dual smokers (both manufactured and RYO cigarettes), d) manufactured plus other types of tobacco products different from RYO and e) other types of tobacco products different from manufactured and RYO cigarettes. Read More

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http://dx.doi.org/10.1016/j.envres.2018.12.006DOI Listing
December 2018

Towards a fuller assessment of benefits to children's health of reducing air pollution and mitigating climate change due to fossil fuel combustion.

Environ Res 2018 Dec 12;172:55-72. Epub 2018 Dec 12.

Abt Associates, Boulder, CO, USA. Electronic address:

Background: Fossil fuel combustion by-products, including particulate matter (PM), polycyclic aromatic hydrocarbons (PAH), nitrogen dioxide (NO) and carbon dioxide (CO), are a significant threat to children's health and equality. Various policies to reduce emissions have been implemented to reduce air pollution and mitigate climate change, with sizeable estimated health and economic benefits. However, only a few adverse outcomes in children have been considered, resulting in an undercounting of the benefits to this vulnerable population. Read More

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http://dx.doi.org/10.1016/j.envres.2018.12.016DOI Listing
December 2018

Effect of humeral tray placement on impingement-free range of motion and muscle moment arms in reverse shoulder arthroplasty.

Clin Biomech (Bristol, Avon) 2019 Feb 5;62:136-143. Epub 2019 Feb 5.

Department of Human Biology, University of Cape Town, Cape Town, South Africa. Electronic address:

Background: It has been suggested that onlay humeral tray placement in reverse shoulder arthroplasty can affect impingement and muscle functionality. This study investigates biomechanical changes to the reversed shoulder using a variety of tray positional configurations.

Methods: The reconstructed scapula and humerus from 12 CT scans were used to customise a 3D biomechanical model of the shoulder. Read More

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http://dx.doi.org/10.1016/j.clinbiomech.2019.02.002DOI Listing
February 2019

'Poetry in motion' a place in the classroom: Using poetry to develop writing confidence and reflective skills.

Nurse Educ Today 2019 Feb 6;76:73-77. Epub 2019 Feb 6.

University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom of Great Britain and Northern Ireland. Electronic address:

Background: Non-traditional students entering nursing programmes at university often experience difficulties with the academic literacy requirements of their courses, in particular academic and reflective writing. Levels of student anxiety may also be affected by other issues including the pressures of managing work, family and study commitments.

Objectives: To explore how classroom-based poetry writing activities might support students in developing their skills as student-writers and reflective practitioners. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.01.026DOI Listing
February 2019

Exploring the experiences of early career academic nurses as they shape their career journey: A qualitative study.

Nurse Educ Today 2019 Feb 5;76:68-72. Epub 2019 Feb 5.

IMPACCT (Centre for Improving Palliative, Aged and Chronic Care through Clinical Research and Translation), University of Technology Sydney, Australia; Johns Hopkins University, Baltimore, MD, United States of America. Electronic address:

Objective: This study aimed to explore the experiences of early career academic nurses as they shape their career path in one Australian university.

Background: The early years of academic career development can be challenging as individuals learn to adjust to the teaching, research and service mission of universities. Tertiary institutions have an obligation to provide future nursing leaders with relevant and timely support during the formative phase of career development, to be successful in a competitive global environment. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.01.021DOI Listing
February 2019

Student perceptions, experiences and support within their current Bachelor of Nursing.

Nurse Educ Today 2019 Feb 6;76:56-61. Epub 2019 Feb 6.

Western Sydney University, School of Nursing & Midwifery, Locked Bag 1797, Penrith, South NSW 2751, Australia. Electronic address:

Background: This study was developed to assist academics and curriculum designers to understand the perspectives and expectations of students when designing a program of study and inclusive of students as partners. The purpose of this qualitative study was to explore the perceptions and experiences of students enrolled in the Bachelor of Nursing (BN).

Settings, Participants, Methods: The setting is a multi-campus university in Australia. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.01.032DOI Listing
February 2019

Narratives in student nurses' knowledge development: A hermeneutical research study.

Authors:
Johanne Alteren

Nurse Educ Today 2019 Feb 6;76:51-55. Epub 2019 Feb 6.

Nord University, Faculty of Nursing and Health Science, Mo I Rana, Norway. Electronic address:

Background: Knowledge development, and how student nurses learn to be nurses, is essential in nurse education and has implications for quality of care. There is a lack of research concerning how student nurses' knowledge development is expressed through narratives and how they deal with challenges in patient situations in professional learning.

Objectives: To clarify the usefulness of narratives in student nurses' knowledge development and the narratives implications for learning in clinical training. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.01.015DOI Listing
February 2019

Migrant Polish women overcoming communication challenges in Scottish maternity services: A qualitative descriptive study.

Midwifery 2019 Feb 7;72:30-38. Epub 2019 Feb 7.

School of Nursing and Midwifery, Robert Gordon University, Garthdee Road, Aberdeen AB10 7AQ, UK.

Background: Migrant women are more likely to experience sub-optimal maternity outcomes and are often described in a problematised way. Communication is crucial in maternity and can be compromised if the language of that service is delivered in a language incomprehensible to migrant women.

Methods: Qualitative descriptive study using 9 in-depth individual interviews with Polish women who recently had experience of local maternity services. Read More

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http://dx.doi.org/10.1016/j.midw.2019.02.004DOI Listing
February 2019

Mobile obstetric and neonatal simulation based skills training in India.

Midwifery 2019 Feb 7;72:14-22. Epub 2019 Feb 7.

Department of Paediatrics, Monash University, Melbourne, Australia.

Background: The developing world has a significantly high risk of women and babies dying during childbirth. Interprofessional simulation training has improved birth practices and outcomes by impacting clinical and non-technical skills like communication, teamwork, leadership and effective use of resources. While these programs have become a training requirement in many high-income countries, they have not been widely introduced in the low-income, low-resource settings. Read More

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http://dx.doi.org/10.1016/j.midw.2019.02.006DOI Listing
February 2019

Differences in the relation between temperament and vocabulary based on children's stuttering trajectories.

J Commun Disord 2019 Jan 25;78:57-68. Epub 2019 Jan 25.

Department of Hearing and Speech Sciences, Vanderbilt University, 1215 21st Avenue South, Suite 8310 MCE South Tower, Nashville, TN 37232-8242, United States.

Purpose: The purpose of this study was to assess the relation between temperament and vocabulary development for children who stutter and persist, children who stutter and recover and children who do not stutter.

Methods: Participants, aged 3;0-4;11 at the start of the study, were followed for two years. They were classified as persisting (n = 10), recovered (n = 26), and non-stuttering (n = 24) based on multiple assessments of stuttering spaced across study participation. Read More

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http://dx.doi.org/10.1016/j.jcomdis.2019.01.004DOI Listing
January 2019

Movie violence acutely affects food choices in young adults.

Eat Behav 2019 Feb 10;33:7-12. Epub 2019 Feb 10.

Nutrition Division, Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Lebanon.

Background: Extensive research has been conducted to investigate the effects of media violence on attitudes, behaviors, and cardiovascular health; however, only few studies have examined its effect on appetite, eating behavior and food preferences. Little attention has been given to understand how movie genre manipulates the physiology and the eating behavior of individuals. The present study aimed at investigating the acute effect of violence content in movies on appetite perception, heart rate and blood pressure, along with food preferences and intake in young individuals. Read More

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http://dx.doi.org/10.1016/j.eatbeh.2019.02.002DOI Listing
February 2019
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