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J Ethnopharmacol 2021 Jun 9:114297. Epub 2021 Jun 9.

Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address:

Ethnopharmacological Relevance: Tabebuia pallida (Lindl.) Miers (T. pallida) is a well-known native Caribbean medicinal plant. Read More

Food Chem 2021 May 30;362:130253. Epub 2021 May 30.

College of Food Science and Technology, Bohai University, National & Local Joint Engineering Research Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products, Jinzhou, Liaoning 121013, China.

The effect of high amylose corn starch (HAS)-fatty acid complexes on the gel properties, protein secondary structure, microstructure, fatty acid content, and sensory properties of surimi under high-temperature treatment were investigated. The formation of HAS-fatty acid complexes increased melting temperature and decreased average particle size of HAS. The addition of HAS-fatty acid complexes significantly improved the breaking force, deformation and whiteness of surimi gels. Read More

J Ethnopharmacol 2021 Jun 8:114304. Epub 2021 Jun 8.

Faculty of Agriculture and Food, Kunming University of Science and Technology, Kunming, 650500, China. Electronic address:

Ethnopharmacological Relevance: Anneslea fragrans Wall. is traditionally used as a folk medicine in treating indigestion, fever, dysentery, diarrhea, and liver inflammation in China, Vietnam and Cambodia. However, its anti-inflammatory activity and mechanism under a safety therapeutic dose as well as the main chemical components have not yet been fully investigated. Read More

Food Chem Toxicol 2021 Jun 8:112327. Epub 2021 Jun 8.

Department of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

Red onion skin waste (ROSW) was analyzed for extraction of naturally occurring 4'-O-glucoside of quercetin, spiraeoside (SPI) with promising biological activities. Reversed-phase high-performance liquid chromatography was used to determine the SPI content in three different solvent extracts of ROSW: water (12.2 mg/g), methanol (27. Read More

J Phys Chem Lett 2021 Jun 11:5695-5702. Epub 2021 Jun 11.

Department of Chemistry, University at Buffalo, State University of New York, Buffalo, New York 14260-3000, United States.

The buried solid/liquid interface between hydrophilic fused silica and binary solvent mixtures of acetonitrile (MeCN) and methanol (MeOH) was studied with vibrational sum-frequency generation (vSFG) spectroscopy. Our data showed that at high relative concentrations of methanol, the Fermi resonance peak in the vSFG spectrum is greatly suppressed, and it progressively gains intensity as methanol is diluted with perdeuterated acetonitrile. This phenomenon is quantified by the Fermi resonance coupling coefficient, , extracted using a two-level model, as well as the experimental intensity ratio, , of the methyl Fermi resonance band to that of the symmetric stretch. Read More

Langmuir 2021 Jun 11. Epub 2021 Jun 11.

Department of Chemistry, University of Virginia, Po Box 400319, Charlottesville, Virginia 22904, United States.

With the microfluidics community embracing 3D resin printing as a rapid fabrication method, controlling surface chemistry has emerged as a new challenge. Fluorination of 3D-printed surfaces is highly desirable in many applications due to chemical inertness, low friction coefficients, antifouling properties, and the potential for selective hydrophobic patterning. Despite sporadic reports, silanization methods have not been optimized for covalent bonding with polymeric resins. Read More

J AOAC Int 2021 Jun 11. Epub 2021 Jun 11.

Université Mohammed V, Faculté de Médicine et de Pharmacie, Laboratoire de Chimie Analytique et Bromatologie, Rabat, Maroc.

Background: Levofloxacin is a third-generation fluoroquinolone that has several advantages over its R-Ofloxacin isomer. It is used to treat different types of infections including urinary and prostatitis.

Objective: New HPLC method for the enantioselective separation of levofloxacin and its chiral impurity was developed and validated to improve the separation of the enantiomers of levofloxacin (impurity-R and active principle-S) by increasing the value of the resolution between the eutomer and the distomer. Read More

J Tradit Chin Med 2021 Jun;41(3):376-380

NPRL, Department of Pharmacognosy, Faculty of Pharmacy, Gomal University D. I. Khan, 29050, Pakistan.

Objective: To investigate the inhibitive efficacy of Nymphoides Indica (L.) Kuntze rhizome extract on α-glucosidase and on cross-link formation of advanced glycation end products (AGEs).

Methods: The plant extracts were prepared by cold maceration and fractionated in solvents of diverse polarity. Read More

Chempluschem 2021 May 28;86(6):870-874. Epub 2021 May 28.

Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysts and Innovative Materials, Fudan University, 200438, Shanghai, P. R. China.

As pure compounds, small carbonyl azides enjoy a bad reputation, due to the high explosive sensitivity and instability they demonstrate. Consequently, most reported examples have only been poorly characterized. The compounds oxalyl diazide (1), carbamoyl azide (2), as well as N,N'-bis(azidocarbonyl)hydrazine (3) were obtained by performing a diazotation reaction on the corresponding hydrazo precursor. Read More

Adv Mater 2021 Jun 10:e2100713. Epub 2021 Jun 10.

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu, 215123, P. R. China.

Anisotropic 3D nanostructures exhibit excellent electrocatalytic activity and stability due to their heterogeneous elemental distribution and unsymmetrical configuration. However, it is still a huge challenge to combine anisotropically distributed elements and anisotropic morphologies within one 3D nanostructure. Herein, 3D [email protected] hemispherical nanostructures ([email protected] H-Ss) are fabricated as highly efficient electrocatalysts for oxidation reaction, which present heterogenous element distribution and anisotropic morphology. Read More

Analyst 2021 Jun 11. Epub 2021 Jun 11.

School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, PR China.

A new fluorescent probe, 3-(benzo[d]thiazol-2-yl)-5-bromosalicylaldehyde-4N-phenyl thiosemicarbazone (BTT), for ratiometric sensing of Zn2+ ions in methanol/HEPES buffer solution (3 : 2, pH = 7.4) is reported in this paper. The presence of Zn2+ ions yields a significant blue shift in the maximum emission of BTT from 570 nm to 488 nm, accompanied by a clear color change from orange to green. Read More

Drug Des Devel Ther 2021 4;15:2417-2430. Epub 2021 Jun 4.

Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.

Introduction: In this research, we used a volumetric absorptive microsampling (VAMS) technique to collect blood samples from the patients. A rapid and simple sample preparation method and LC-MS.MS assay was then developed and validated for the simultaneous analysis of tamoxifen and its three active metabolites. Read More

Sci Rep 2021 Jun 10;11(1):12319. Epub 2021 Jun 10.

Thermodynamics and Process Engineering, Technical University of Berlin, Ernst-Reuter-Platz 1, 10587, Berlin, Germany.

The Fick diffusion coefficient matrix of the highly associating quaternary mixture water + methanol + ethanol + 2-propanol as well as its ternary and binary subsystems is analyzed with molecular dynamics simulation techniques. Three of the ternary subsystems are studied in this sense for the first time. The predictive capability of the employed force fields, which were sampled with the Green-Kubo formalism and Kirkwood-Buff integration, is confirmed by comparison with experimental literature data on vapor-liquid equilibrium, shear viscosity and Fick diffusion coefficient, wherever possible. Read More

J Biotechnol 2019 21;306S:100001. Epub 2018 Dec 21.

Department of Environmental Chemistry and Engineering, Tokyo Institute of Technology, G1-14, Nagatsuta-cho, Midori-ku, Yokohama 226-8502, Japan.

The influence of metal removal with a chelating reagent, ethylenediaminetetraacetic acid (EDTA), and metal reconstitution on the activity of particulate methane monooxygenase (pMMO) from Methylosinus trichosporium OB3b toward methane oxidation to methanol was investigated. For this study, a membrane fraction containing pMMO and bacterial cell membrane components was prepared. pMMO activity was assessed with two different reductants, nicotinamide adenine dinucleotide (NADH) and 2,3,5,6-tetramethyl hydroquinone (duroquinol). Read More

Sci Total Environ 2021 May 29;790:148132. Epub 2021 May 29.

School of Environment and Energy, South China University of Technology, Guangzhou 510006, PR China; Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control, Guangzhou 510006, PR China; Guangdong Provincial Engineering and Technology Research Centre for Environmental Risk Prevention and Emergency Disposal, Guangzhou 510006, PR China. Electronic address:

A series of Fe-based metal organic framework derived materials were prepared by thermal treating MIL-100(Fe) in nitrogen atmosphere for adsorption removal of oxygenated volatile organic compounds (OVOCs) such as methanol, formaldehyde and acetone under dynamic conditions. The experimental results showed that the partially carbonized M-350 material obtained by calcining MIL-100(Fe) at 350 °C exhibited the best adsorption performance and high stability. The breakthrough adsorption capacity of M-350 for methanol was 61. Read More

J Pharm Biomed Anal 2021 May 21;203:114143. Epub 2021 May 21.

Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.

Vincristine (VCR) is an integral part of chemotherapy regimens in the US and in developing countries. There is a paucity of information about its disposition and optimal therapeutic dosing. VCR is preferentially metabolized to its major M1 metabolite by the polymorphic CYP3A5 enzyme, which may be clinically significant as CYP3A5 expression varies across populations. Read More

J Ethnopharmacol 2021 Jun 7:114265. Epub 2021 Jun 7.

College of Pharmacy and Research Institute of Pharmaceutical Sciences,Seoul National University, 1, Gwanak-ro, Gwanak-gu,Seoul 08826,Republic of Korea. Electronic address:

Ethnopharmacological Relevance: Penthorum chinense has been used in East Asia for the treatment of cholecystitis, infectious hepatitis, jaundice and to treat liver problems. Recent evidences provided the potential for the clinical use of P. chinense in the treatment of metabolic disease. Read More

Angew Chem Int Ed Engl 2021 Jun 10. Epub 2021 Jun 10.

East China Normal University, School of Chemistry and molecular Engineering, 200241, Shanghai, CHINA.

The hydrogenation of sequestrated CO 2 to methanol can reduce CO 2 emission and establish a sustainable carbon circuit. However, the transformation of CO 2 into methanol is challenging because of the thermodynamic equilibrium limitation and the deactivation of catalysts by water. In the present work, different reactor types have been evaluated for CO 2 catalytic hydrogenation to methanol. Read More

ACS Appl Mater Interfaces 2021 Jun 10. Epub 2021 Jun 10.

Department of Chemical Engineering, Indian Institute of Technology Tirupati, Tirupati 517506, India.

Engineering of the interface for tuning the structural, functional, and electronic properties of materials via the formation of heterostructure composites exhibits immense potential in the current research scenario. This study reports a novel ternary composite synthesized by decoration of zero-dimensional Pd nanoparticles (NPs) and two-dimensional (2D) graphite oxide (GO) sheets in the UiO-66 metal-organic framework (MOF). A mixed matrix membrane was fabricated by incorporating this composite in the SPEEK polymer matrix, which exhibited higher selectivity compared to commercial Nafion 117. Read More

Biomed Chromatogr 2021 Jun 10:e5192. Epub 2021 Jun 10.

Department of Chemistry, JNTUH College of Engineering Jagitial, Nachupally (Kondagattu), Telangana State, India.

A Reversed Phase High Performance Liquid Chromatography (RP-HPLC) method was developed and validated for the identification and quantification of the Moxifloxacin hydrochloride related substances in finished dosage forms. Efficient chromatographic separation has been achieved on a Agilent C18 (150 x 4.6) mm, 5μm column with mobile phase (0. Read More

Biomed Chromatogr 2021 Jun 10:e5195. Epub 2021 Jun 10.

Department of Forensic Medicine and Medical Law, Faculty of Medicine and Dentistry, Palacký University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic.

Direct oral anticoagulants are an alternative to anticoagulants based on vitamin K antagonists. Monitoring of direct oral anticoagulant concentration levels is necessary in specific cases only (e.g. Read More

Environ Sci Pollut Res Int 2021 Jun 9. Epub 2021 Jun 9.

Department of Chemical Engineering, National Institute of Technology, M.G. Avenue, Durgapur, West Bengal, 713209, India.

The presented study discusses biodiesel synthesis by utilizing two wastes: Mesua ferrea Linn (MFL) seed shells (inert support for developing catalysts) and used cooking oil (feedstock). The MFL shells were used for heterogeneous acid and base catalyst development through carbonization, steam activation and subsequent doping of HSO or KOH, which upon instrumental examination showed effective doping of functional groups on the MFL char. The conversion approach uses methanol with sulfonated char (SC) for esterification, while the second stage utilizes 2-propanol for transesterification with KOH-doped char (KC) as a catalyst. Read More

J Chromatogr Sci 2021 Jun 9. Epub 2021 Jun 9.

Department of Clinical Research, School of Biological and Biomedical Sciences, Galgotias University, Greater Noida, Uttar Pradesh, 226001, India.

A simple, fast and extremely sensitive for estimating Pimavanserin in human (K2EDTA) plasma using ultra high-performance liquid chromatography combined with tandem mass spectrometry (UHPLC-MS/MS) was newly developed and validated. Sample extraction was accomplished using a partition liquid extraction (LLE-liquid-liquid extraction) procedure utilizing extraction solvent, methyl tertiary butyl ether. Separation of the components, chromatography, was done using a C18 chromatographic analytical column employing acetonitrile:methanol: 0. Read More

Biotech Histochem 2021 Jun 10:1-6. Epub 2021 Jun 10.

Syngenta Limited, Jealott's Hill International Research Centre, Bracknell, UK.

Automated methods exist for double staining bone and cartilage in fetal rat, rabbit and mice using alizarin red S and Alcian blue. None of the published methods produce consistently stained bone and cartilage in mouse fetuses. Consequently, we modified an automated staining method for use with mouse fetuses. Read More

J Chromatogr B Analyt Technol Biomed Life Sci 2021 May 14;1177:122755. Epub 2021 May 14.

Alpine Foundation for Life Sciences (FASV), 6718 Olivone, Switzerland.

This study describes two bioanalytical methods for the quantitation of the two methadone enantiomers in dried matrix spots using high performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS) and high performance supercritical chromatography tandem mass spectrometry (HPSFC-MS/MS). Dried matrix spots were obtained by spotting 10 µL of each sample fluid on a Whatman paper. Methadone and its main metabolite, EDDP, were extracted with 100 µL methanol and subsequently injected into the LC-MS/MS and SFC-MS/MS systems. Read More

J Chromatogr A 2021 May 24;1651:462272. Epub 2021 May 24.

Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. Electronic address:

Long-term stability of retention times of a wide range of analytes has been evaluated using eight different stationary phases. These were from a single manufacturer to minimize the differences in silanol activity caused by the manufacturing process. The tested stationary phases included bridge ethylene hybrid, 2-ethylpyridine bridge ethylene hybrid with direct modification of silica particles, bidentate crosslinked charged surface hybrid fluorophenyl, bidentate crosslinked high strength silica C18, and propanediol linked phases including diol (pure propanediol linker), and three phases based on diol further modified with 2-picolylamine, diethylamine, and 1-aminoanthracene group. Read More

J Chromatogr A 2021 May 24;1651:462276. Epub 2021 May 24.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, Assiut 71515, Egypt.

In this work, a fast, versatile, and convenient dispersive solid-phase micro-extraction (DSPME) method is combined with a spectro-densitometric technique for the analysis of zolmitriptan (ZOLM) in biological fluids. FeO/FeOOH magnetic nanocomposites (MNCs) were prepared by a co-precipitation method in aqueous solutions and utilized subsequently as a sorbent in DSPME. By coupling DSPME with high-performance thin-layer chromatography (HPTLC) with fluorescence detection, the preconcentration and determination of (ZOLM) in presence of metoclopramide (MET) and paracetamol (PARA), which are prescribed as an adjuvant therapy with ZOLM, was accomplished. Read More

J Ethnopharmacol 2021 Jun 6:114307. Epub 2021 Jun 6.

Department of Biotechnology and Microbiology, Dr, Janaki Ammal Campus, Thalassery, Kannur-670661, Kerala, India. Electronic address:

Ethnopharmacological Relevance: The Indian tradition system of medicine enlists a large number of plants for basic health care. Leucas lavandulifolia is mentioned in the ayurvedic medicinal system and also used among the folklores. The plant is used for the treatment of fever, asthma, psoriasis, dermatitis and healing snake bites. Read More

ACS Appl Mater Interfaces 2021 Jun 9. Epub 2021 Jun 9.

National Base for International Science & Technology Cooperation, National Local Joint Engineering Laboratory for Key Materials of New Energy Storage Battery, Hunan Province Key Laboratory of Electrochemical Energy Storage & Conversion, School of Chemistry, Xiangtan University, Xiangtan 411105, China.

Transition metal-nitrogen-carbon (TM-N-C) nanomaterials are promising platinum-based substitutes for the oxygen reduction reaction (ORR). However, large-scale commercial production of high-efficiency, durable TM-N-C catalysts remains a formidable challenge. In this work, a facile ″ZIF-on-ZIF″ strategy is first adopted to design [email protected] core-shell polyhedral nanocages, and then, ferrocene (Fc) is added to form [email protected]@Fc double-layer encapsulating polyhedral nanocages. Read More

Plant Foods Hum Nutr 2021 Jun 9. Epub 2021 Jun 9.

Faculty of Science, University of Novi Sad, Trg Dositeja Obradovića 3, Novi Sad, Serbia.

The possibility to prevent nutrition-related diseases that include scavenge of free radicals and to block chain reactions is very important and significant for human well-being. The aim of this study was to analyse different basil extracts, determine the relationship between total phenolic/flavonoid content and antioxidant activity in order to optimize its application in industry. The extraction involved different solvents (ethanol, methanol and water), extraction time (10 and 30 min and 24, 48 and 72 h), plant fragmentation level (0. Read More