660 results match your criteria Mesoblastic Nephroma Imaging
J Nippon Med Sch 2018 ;85(5):297-299
Department of Radiology, Shandong Provincial Hospital affiliated to Shandong University.
Congenital mesoblastic nephroma (CMN) is a rare tumor of infancy. CMNs can be histologically divided into classic, cellular, and mixed subtypes. Cellular CMNs are difficult to differentiate from Wilms tumors. Read More
Turk J Pediatr 2018 ;60(2):198-200
Departments of Pediatric Nephrology, Tepecik Training and Research Hospital, İzmir, Turkey.
Soyaltın E, Alaygut D, Alparslan C, Özdemir T, Arslansoyu-Çamlar S, Mutlubaş F, Kasap-Demir B, Yavaşcan Ö. A rare cause of neonatal hypertension: Congenital mesoblastic nephroma. Turk J Pediatr 2018; 60: 198-200. Read More
J Pediatr Urol 2018 Aug 1. Epub 2018 Aug 1.
Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guanzhou, China. Electronic address:
Introduction: Congenital mesoblastic nephroma (CMN) is a common solid renal tumor in the neonate. Congenital mesoblastic nephroma can be divided into classic, cellular, and mixed types. The prognosis of CMN is very optimistic. Read More
Pediatr Int 2018 Oct 15;60(10):962-965. Epub 2018 Oct 15.
Department of Pediatric Surgery, Hachinohe City Hospital, Aza Bisyamondaira, Hachinohe, Japan.
Background: The aim of this study was to assess long-term residual kidney function after unilateral nephrectomy for non-syndromic Wilms tumor (NSWT).
Methods: Of the patients who underwent one-sided NSWT at Tohoku University Hospital between 1977 and 2003, nine were followed up until age ≥18 years. For these nine patients, we retrospectively evaluated estimated glomerular filtration rate (eGFR) in childhood (3-10 years old), adolescence (11-17 years old) and adulthood (≥18 years). Read More
Nat Commun 2018 06 18;9(1):2378. Epub 2018 Jun 18.
Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.
Soft tissue tumors of infancy encompass an overlapping spectrum of diseases that pose unique diagnostic and clinical challenges. We studied genomes and transcriptomes of cryptogenic congenital mesoblastic nephroma (CMN), and extended our findings to five anatomically or histologically related soft tissue tumors: infantile fibrosarcoma (IFS), nephroblastomatosis, Wilms tumor, malignant rhabdoid tumor, and clear cell sarcoma of the kidney. A key finding is recurrent mutation of EGFR in CMN by internal tandem duplication of the kinase domain, thus delineating CMN from other childhood renal tumors. Read More
Pediatr Blood Cancer 2018 Oct 12;65(10):e27271. Epub 2018 Jun 12.
Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Mesoblastic nephroma is the most frequent renal tumor in newborns and young infants, and the cellular type is characterized by an ETV6-NTRK fusion, which constitutively activates the tropomyosin-related kinase (TRK) signaling pathway. Larotrectinib is a highly selective TRK inhibitor with activity in adult and pediatric patients who have TRK fusions. We present a rare case of a patient with mesoblastic nephroma metastatic to bone who had a dramatic response to larotrectinib. Read More
Turk J Urol 2018 May 1;44(3):278-280. Epub 2018 May 1.
Department of Surgical and Biomedical Sciences, Division of Radiology 2, S. Maria della Misericordia Hospital, Perugia University, Perugia, Italy.
Turk J Urol 2018 May 1;44(3):268-273. Epub 2018 May 1.
Division of Pediatric Oncology, Mersin University, Mersin, Turkey.
Objective: Renal tumors are not uncommon in children. In this study, we aimed to evaluate the clinical and pathological features of renal tumors in children.
Material And Methods: Between January 2008 and December 2017, the records of children with renal tumors in our institution were retrospectively analyzed. Read More
Am J Surg Pathol 2018 Jul;42(7):927-935
Department of Pathology, University of California San Francisco, San Francisco, CA.
Activating neurotrophic receptor kinase (NTRK) fusions define certain pediatric mesenchymal tumors, including infantile fibrosarcoma and cellular mesoblastic nephroma. Traditionally, molecular confirmation of these fusions has included either fluorescent in situ hybridization for ETV6 rearrangements or reverse-transcriptase polymerase chain reaction for the classic ETV6-NTRK3 fusion. However, these methods overlook variant NTRK rearrangements, which are increasingly appreciated as recurrent events in a subset of pediatric mesenchymal tumors. Read More
J Indian Assoc Pediatr Surg 2018 Apr-Jun;23(2):66-69
Department of Paediatric Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Background: Pretreatment core biopsy of pediatric renal tumors has been advocated by United Kingdom Children's Cancer Study Group to circumvent the disadvantage of International Society of Paediatric Oncology protocol, where neoadjuvant chemotherapy initiated without histopathological confirmation can result in over- or under-treatment.
Aim: This study aims (a) to assess if pretherapy core biopsy correlates with the nephrectomy biopsy; (b) to assess if neoadjuvant chemotherapy changes Wilms tumor (WT) histology, and (c) to assess the incidence of biopsy site recurrence.
Materials And Methods: Seventy-six children from 2005 to 2016 with renal tumors who underwent a pretherapy core biopsy were included in the study. Read More
Pediatr Blood Cancer 2018 Apr 29;65(4). Epub 2017 Dec 29.
Kiel Pediatric Tumor Registry, Department of Pediatric Pathology, Christian-Albrechts-University Kiel, Kiel, Germany.
Background: Congenital mesoblastic nephroma (MN) is a rare pediatric renal tumor representing approximately 5% of all pediatric renal tumors. Three different types of MN are distinguished histologically: classical, cellular, and mixed. A frequent genetic alteration is the translocation t(12;15) resulting in a fusion of the ETV6 gene on 12p13 and the NTRK3 gene on 15p15 that occurs almost exclusively in cellular MN. Read More
Radiologe 2018 Jan;58(1):3-9
Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Giessen, Justus-Liebig Universität Giessen, Klinikstraße 33, 35392, Giessen, Deutschland.
Mesenchymal tumors in childhood comprise benign and malign entities and differ regarding typical sites of manifestation, age peak and clinical symptoms. In some cases biopsy is mandatory. If nephroblastoma is a possible diagnosis, biopsy must be avoided by all means in order to avoid biopsy tract metastasis. Read More
Indian J Med Paediatr Oncol 2017 Jul-Sep;38(3):357-359
Department of Paediatric Surgery, LTMG Hospital, Mumbai, Maharashtra, India.
Metanephric stromal tumor (MST) of kidney is an under-reported benign stromal specific renal neoplasm with good prognosis. This tumor is to be differentiated from congenital mesoblastic nephroma and clear-cell sarcoma of the kidney. In this case report, we describe the imaging, gross, and microscopic features of MST with ischemic left kidney in a 1-month-old child and discuss treatment with relevant literature. Read More
Mod Pathol 2018 03 3;31(3):463-473. Epub 2017 Nov 3.
Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Infantile fibrosarcoma and congenital mesoblastic nephroma are tumors of infancy traditionally associated with the ETV6-NTRK3 gene fusion. However, a number of case reports have identified variant fusions in these tumors. In order to assess the frequency of variant NTRK3 fusions, and in particular whether the recently identified EML4-NTRK3 fusion is recurrent, 63 archival cases of infantile fibrosarcoma, congenital mesoblastic nephroma, mammary analog secretory carcinoma and secretory breast carcinoma (tumor types that are known to carry recurrent ETV6-NTRK3 fusions) were tested with NTRK3 break-apart FISH, EML4-NTRK3 dual fusion FISH, and targeted RNA sequencing. Read More
Pediatr Surg Int 2017 Nov 30;33(11):1183-1188. Epub 2017 Aug 30.
Department of Paediatric Surgery, The Children's Hospital at Westmead, Sydney Medical School, The University of Sydney, Cnr Hawkesbury Road and Hainsworth Street, Westmead, NSW, 2145, Australia.
Purpose: Fifty years ago, Bolande described Congenital Mesoblastic Nephroma (CMN) as a benign lesion. Unexpected aggressive clinical behaviors prompted a sub-classification based on histology. Recent molecular genetic evidence has identified the aggressive cellular variant to be the renal manifestation of congenital infantile fibrosarcoma. Read More
Med Ultrason 2016 Dec;19(3):327-329
IMOGEN, Centre of Advanced Research Studies, Cluj-Napoca, Romania.
Cystic nephroma is a rare and benign renal tumour of unknown origin, usually diagnosed in the first years of childhood or during adult life. To our knowledge, there are no records in the literature of this particular tumour being descried prenatally. We present a case of a fetus diagnosed with cystic nephroma on 16 weeks of gestation. Read More
J Neonatal Surg 2017 Apr-Jun;6(2):45. Epub 2017 Apr 15.
Department of Pediatric Surgery, SCB Medical College, Cuttack, Odisha, India.
Pediatr Neonatol 2018 02 11;59(1):65-70. Epub 2017 Jul 11.
Meenakshi Mission Hospital and Research Centre, Madurai, India. Electronic address:
Background: Neonatal tumors are different from tumors of the older children and knowledge gained from treating older children can not be extrapolated to neonates. Neonates have immature physiology and their haematopoietic and immune systems are not fully developed and the response to therapy is unpredictable. Hence it is imperative to study these tumors as separate entity. Read More
Pathologe 2017 Jul;38(4):278-285
Abteilung für Zelluläre Pathologie, Universitätsklinikum Wales, Universität Cardiff, Cardiff, Großbritannien.
Solid tumors in childhood are extremely rare entities, which are usually treated in specialized centers. Diagnosis and therapy are carried out according to a joint European protocol, whereby the pathological evaluation and therapy are carried out according to international guidelines. For the correct diagnosis and/or therapy of most tumors, analysis of specific genetic changes is mandatory; therefore, tumors have to be adequately sampled for parallel genetic analysis during the pathological work-up. Read More
Pediatr Blood Cancer 2018 Jan 25;65(1). Epub 2017 Apr 25.
Pediatric Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Appl Immunohistochem Mol Morphol 2018 Nov/Dec;26(10):721-726
Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Pediatric renal tumors (PRT) with small round blue or spindle cell morphology can be diagnostically challenging and only a limited number of immunohistochemical markers have been documented to help in the diagnosis: paired box (Pax) 2 and nerve growth factor receptor (NGFR) positivity have been demonstrated in Wilms tumor (WT) and clear cell sarcoma of the kidney (CCSK), respectively. However, the immunohistochemical expression of these markers in other PRT remains unknown. This study investigated Pax8, Pax2, and NGFR immunophenotype in a large series of PRT. Read More
J Obstet Gynaecol 2017 Jul 17;37(5):670-672. Epub 2017 Mar 17.
d Santa Maria del Carmine Hospital , Provincial Health Care Services, Institute of Pathology , Rovereto , Italy.
Foetal magnetic resonance imaging (MRI) plays an increasingly important role in the diagnosis of foetal abnormalities. Over the years, we have successfully applied bi-parametric MRI (bp-MRI) to the following obstetric conditions: (1) neurologic vascular diseases; (2) assessment of lung parenchyma maturation; (3) renal pathologies, such as polycystic kidney, suspected renal infarction, unilateral or bilateral renal agenesis; (4) placental pathologies, as twin-twin transfusion syndrome or placenta accreta; (5) benignant and malignant congenital tumours or cysts of the liver, such as haemangioendothelioma, hepatoblastoma or metastatic neuroblastoma, of the kidney (e.g. Read More
J Neonatal Perinatal Med 2017 ;10(1):113-118
Department of Pediatrics, Division of Neonatology, College of Medicine, Univeristy of Kentucky, Lexington, KY, USA.
Congenital mesoblastic nephroma (CMN) is the most common renal tumor of infancy; however, it occurs infrequently with an incidence of 1 : 125,000. The cellular and classical variants are the most common subtypes of tumors, with a mixed variant occurring infrequently. We describe two cases of mixed variant CMN, which presented within days of each other differing in their clinical behavior. Read More
BMC Cancer 2017 02 21;17(1):146. Epub 2017 Feb 21.
Laboratorio de Oncología Molecular, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), AGC Laboratorio de Medicina, Hospital Universitario Central de Asturias (HUCA), Oviedo, 33011, Spain.
Background: DICER1 syndrome is a pediatric cancer predisposition condition causing a variety of tumor types in children and young adults. In this report we studied a family with two relatives presenting a variety of neoplastic conditions at childhood.
Methods: Germ-line mutation screening of the complete coding region of the DICER1 gene in genomic DNA from the proband was performed. Read More
Neonatal Netw 2017 Jan;36(1):32-39
The most common nonencapsulated solid renal tumor in the neonatal period is congenital mesoblastic nephroma. Mesoblastic nephroma is a solid lesion originating within or extending from the renal parenchyma. These tumors proliferate rapidly, typically within 3-6 months after birth. Read More
Pediatr Blood Cancer 2017 Jul 26;64(7). Epub 2017 Jan 26.
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Read More
Pediatr Blood Cancer 2017 Aug 18;64(8). Epub 2017 Jan 18.
Foundation Medicine, Inc., Cambridge, Massachusetts.
Background: NTRK fusions are known oncogenic drivers and have recently been effectively targeted by investigational agents in adults. We sought to assess the frequency of NTRK fusions in a large series of pediatric and adolescent patients with advanced cancers.
Procedure: Genomic profiles from 2,031 advanced cancers from patients less than 21 years old who were assayed with comprehensive genomic profiling were reviewed to identify NTRK fusions. Read More
J Pediatr Hematol Oncol 2017 07;39(5):355-361
*Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University †Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Ministry of Education, Hematology Oncology Center ‡Center of Clinical Epidemiology & Evidence-based Medicine §Department of Pathology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
It has been reported that germline DICER1 mutations correlate with a distinctive human disease syndrome. Many published studies within this field have been conducted based on rare cases. We systematically searched bibliographic databases, including PubMed, Embase, and COSMIC for articles which are related to diseases covered by DICER1 syndrome. Read More
J Pediatr Hematol Oncol 2017 03;39(2):103-107
Departments of *Pediatrics, Pediatric Residency Program ‡Pediatrics, Division of Pediatric Hematology/Oncology/Bone Marrow Transplant §Biostatistics, The Research Institute, Nationwide Children's Hospital Departments of †Surgery, Division of Pediatric Surgery ∥Pathology and Laboratory Medicine, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, OH.
Wilms tumor (WT) is the most prevalent pediatric renal tumor and most commonly occurs between ages 1 and 5 years. Data are lacking on children younger than 12 months with renal tumors. The cancer registry at the authors' institution was queried to identify patients 12 months and younger with renal masses. Read More
Hum Pathol 2017 02 18;60:32-36. Epub 2016 Oct 18.
Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL - 60611. Electronic address:
Metanephric stromal tumors (MSTs) are rare renal stromal tumors that predominantly affect children. They belong to the metanephric family of tumors, along with metanephric adenofibroma and metanephric adenoma. The previous documentation of BRAF exon 15 mutations in 88% of metanephric adenomas and in isolated cases of metanephric adenofibroma prompted us to investigate the prevalence of these mutations in MSTs and in other pediatric renal stromal tumors. Read More
Indian J Med Res 2016 May;143(Supplement):S59-S67
Department of Pathology, University College of Medical Sciences, Delhi, India.
Background & Objectives: Renal tumours constitute about 7 per cent of all neoplasms in children. It is important to differentiate Wilms' tumour (commonest tumour) from non-Wilms' tumours. The aim of this study was to evaluate the immunoexpression and diagnostic role of Wilms' tumour-1 protein (WT1) in paediatric renal tumours. Read More
Zhonghua Bing Li Xue Za Zhi 2016 Sep;45(9):646-7
Eur J Pediatr Surg 2017 Feb 17;27(1):74-80. Epub 2016 Aug 17.
Pediatric Surgery Unit, Department of Pediatrics and Infantile Neuropsychiatry, Azienda Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Children with unilateral renal tumor (URT) and preoperative renal dysfunction (PRD) may benefit from nephron-sparing surgery (NSS). To test this hypothesis, we studied the outcome of baseline renal function after nephrectomy or NSS among children with URT. Retrospective records review of children with URT who underwent nephrectomy (25 children) or NSS (11 children) at our institution. Read More
Fetal Pediatr Pathol 2016 2;35(6):376-384. Epub 2016 Aug 2.
a Department of Pathology , Istanbul Faculty of Medicine, Istanbul University , Istanbul , Turkey.
Objective: We aimed to define the histopathologic features and proliferative rate of congenital mesoblastic nephroma (CMN) as a risk factor for recurrence.
Methods: Fourteen cases of CMN among 138 registered pediatric renal tumors were retrospectively reviewed. The prognostic impact for mitotic rate and Ki67 index was investigated. Read More
Cell Biol Int 2016 Oct 1;40(10):1041-9. Epub 2016 Aug 1.
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Pulmonary mesenchymal stem cells (PMSCs) have great potential in lung tissue engineering and represent attractive candidates for disease treatment in human and veterinary research. However, a reliable method for isolation and localization of porcine PMSCs in situ is still uncertain. In this study, we successfully isolated PMSCs from Wuzhishan miniature pig embryos in vitro and also attempted to unravel its fundamental differentiation potential and biological characteristics. Read More
Diagn Cytopathol 2016 Oct 21;44(10):823-7. Epub 2016 Jun 21.
Department of Pathology, IPGME&R, Kolkata, India.
Congenital mesoblastic nephroma (CMN) is a rare pediatric renal neoplasm, occurring most commonly in the first few months of life, with a favourable clinical outcome. Accurate pre-operative cytological diagnosis of this entity is important as pre-operative chemotherapy is not recommended and surgery is the treatment of choice. Cytodiagnosis of this rare tumor is discussed in only a few case reports. Read More
J Indian Assoc Pediatr Surg 2016 Apr-Jun;21(2):61-5
Department of Paediatric Surgery, Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal, India.
Aims: Scrutiny over the clinical behaviors, management, and the final outcome of some rare renal neoplasm in order to find out some hidden facts about these tumors which are playing an important role in the disease course and its management.
Materials And Methods: Retrospective evaluation of uncommon (non-Wilms') renal neoplasm in the pediatric population in a tertiary care center. Fifteen cases of uncommon renal tumors were treated in our institution over the last 5 years (January 2008 to December 2012). Read More
Pathology 2016 Jan 18;48(1):47-50. Epub 2015 Dec 18.
Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, United States.
Mesoblastic nephroma (MN) is the most common renal tumour in the first 3 months of life and accounts for 3-5% of all paediatric renal neoplasms. To further understand the morphological variants of MN, we identified 19 cases of MN (five classic, eight cellular and six mixed) and examined each case for markers known to be important in urogenital embryological development (PAX8, WT1 and RCC), stem cell associated markers (Oct 4, CD34 and c-kit), muscle/myofibroblastic markers (muscle specific actin, calponin and h-caldesmon), aberrant transcription factors, cell cycle regulation and other oncogenic proteins (p16, cyclin D1 and beta-catenin). Fluorescence in situ hybridisation (FISH) testing for ETV6-NTRK3 gene fusion/rearrangement revealed further differentiation between the subtypes with ETV6-NTRK3 gene fusion detected in 0/5 of the classic MN, 8/8 of the cellular MN and 5/6 of the mixed MN cohorts, respectively. Read More
Radiographics 2016 Mar-Apr;36(2):499-522
From the Department of Radiology and Radiological Sciences (E.M.C.), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (A.R.G.), 4301 Jones Bridge Rd, Bethesda, MD 20814; Pediatric Radiology Section, American Institute for Radiologic Pathology, Silver Spring, Md (E.M.C.); and Department of Pathology, Eastern Virginia Medical School, Norfolk, Va (R.M.C.).
Wilms tumor is the second most common pediatric solid tumor and by far the most common renal tumor of infants and young children. As most tumors are large at presentation and are treated with nephrectomy, the role of imaging is primarily in preoperative planning and evaluation for metastatic disease. However, with treatment protocols increasingly involving use of preoperative (neoadjuvant) chemotherapy (the standard in Europe) and consideration of nephron-sparing surgery, the role of imaging is evolving to include providing initial disease staging information and a presumptive diagnosis to guide therapy. Read More
Urol Ann 2016 Jan-Mar;8(1):114-7
Department of Urology, University of Arkansas Medical Sciences, Little Rock, Arkansas, USA.
Mixed epithelial stromal tumor (MEST) is rare and typically benign renal cystic neoplasm that cannot be clinically distinguished from cystic renal cell carcinoma. Its mainstay course of diagnosis and treatment remains surgical excision. Recurrence and malignant transformation is rare but has previously been described. Read More
Radiol Bras 2015 Nov-Dec;48(6):396-8
PhD, Associate Professor, Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil. (In memoriam).
A male child born at 27 weeks, weighting 1305 g and presenting with a right-sided abdominal tumor. Computed tomography scan demonstrated the presence of a solid mass compressing the right kidney. Puncture biopsy revealed congenital mesoblastic nephroma. Read More
Urol Case Rep 2015 Sep 26;3(5):157-60. Epub 2015 Jun 26.
Division of Urology, The Children's Hospital of Philadelphia, Philadelphia, USA.
A 25 4/7 week boy was born with a prenatal diagnosis of polyhydramnios and enlarged left kidney. Over the next 2 months serial ultrasounds demonstrated abnormal growth of the kidney, with 28.9% split function. Read More
Mymensingh Med J 2015 Oct;24(4):856-8
Dr Sk Amirul Islam, Assistant Registrar, Department of Uro-Oncology, National Institute of Cancer Research & Hospital, Dhaka, Bangladesh.
Mesoblastic nephroma is an uncommon renal tumor of infancy and rarely occurs in adults. We report a case of mesoblastic nephroma in adult. A 22-year-old woman, who presented with left flank pain, was found to have a left renal mass by abdominal ultrasonography. Read More
Urology 2016 Feb 23;88:189-91. Epub 2015 Nov 23.
Department of Paediatric Surgery and Urology, Children's Hospital at Westmead, Sydney, New South Wales, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Congenital mesoblastic nephroma (CMN) is the most frequent renal neoplasm of newborns and young infants. Four cases presenting with hemorrhagic manifestations have been reported in the English literature (Hu et al, 2006; Bolande et al, 1967). We report the unusual clinical and radiographic findings of a 2-day-old neonate with hematuria secondary to a CMN. Read More
Yi Chuan 2015 10;37(10):1036-43
School of Life Sciences, Xiamen University, Xiamen 361102, China.
The amphioxus is a promising animal model for evolutionary-developmental studies due to its key position on the animal phylogenetic tree. In the present study, we reported a genetically modified amphioxus strain on the Hedgehog (Hh) gene locus using the TALEN method. The result showed that our TALEN pair injection could bring about 34% mutations in the amphioxus Hh coding region. Read More
J Obstet Gynaecol 2016 14;36(3):340-4. Epub 2015 Oct 14.
a Department of Obstetrics and Gynecology , Jichi Medical University , Tochigi , Japan.
To characterise congenital mesoblastic nephroma (CMN), with special emphasis on polyhydramnios and the neonatal prognosis, we summarise 31 CMN patients (30 reported patients and the present patient). CMN was detected at a median of 30 weeks' gestation, and infants were delivered at a median of 34 weeks' gestation. Of 27 patients with available data, 19 (70%) had polyhydramnios, of which 8 required amnio- drainage. Read More
Obstet Gynecol Sci 2015 Sep 22;58(5):405-8. Epub 2015 Sep 22.
Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Congenital mesoblastic nephroma is a rare renal tumor that is diagnosed during pregnancy and is associated with polyhydramnios, prematurity, and neonatal hypertension. Differential diagnoses include Wilms tumor, adrenal neuroblastoma, and other abdominal tumors. We report a case of congenital mesoblastic nephroma detected by prenatal ultrasonography as a large fetal renal mass with polyhydramnios at 32 weeks of gestation. Read More