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Int Immunopharmacol 2022 May 18;108:108852. Epub 2022 May 18.

Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, PR China. Electronic address:

Isoliquiritin apioside (IA), a critical ingredient of Glycyrrhizae radix et rhizoma, has been unveiled to possess remarkable pharmacological activity against oxidative stress and inflammation. However, the potential roles of IA in intestinal ischemia/reperfusion (I/R)-induced acute lung injury (ALI) have not been reported yet. In the present study, we explored the effects of IA on I/R-induced ALI, and also clarified the possible mechanisms. Read More

Ann Vasc Surg 2022 May 17. Epub 2022 May 17.

From the Advanced Endovascular Aortic Research Program Mayo Clinic, 200 1(st) St NW, Rochester, MN 55905. Electronic address:

Objectives: To evaluate outcomes following urgent or emergent fenestrated-branched endovascular aortic repair (F-BEVAR) for pararenal (PRA) and thoracoabdominal aortic aneurysms (TAAA) in patients considered high-risk for open repair.

Methods: A retrospective, single institution evaluation of outcomes following F-BEVAR of symptomatic, rapidly enlarging, or ruptured PRA or TAAA treated with physician modified endograft (PMEG) and company manufactured devices (CMD). Outcomes were technical success, 30-day morbidity and mortality, and one year aortic related outcomes. Read More

Khirurgiia (Mosk) 2022 (5):18-24

Vishnevsky National Medical Research Center of Surgery, Moscow, Russia.

Objective: To analyze the mechanisms of non-occlusive mesenteric ischemia (NOMI) after digestive tract surgery.

Material And Methods: NOMI occurred in 10 (0.4%) patients after reconstructive digestive tract surgery between 2015 and 2021. Read More

Clin Med (Lond) 2022 May;22(3):282-284

Wexham Park Hospital, Slough, UK

A 60-year-old woman presented with sudden-onset epigastric pain, vomiting and small volume rectal bleeding. She had a history of mechanical mitral valve replacement, for which she was on warfarin. Computed tomography (CT) angiography of the abdomen showed gallstones, a fluid-filled stomach and faecal loading. Read More

BMC Med Imaging 2022 May 16;22(1):90. Epub 2022 May 16.

Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.

Background: Endovascular revascularization has become the first-line treatment of chronic mesenteric ischemia (CMI). The qualitative visual analysis of digital subtraction angiography (DSA) is dependent on observer experience and prone to interpretation errors. We evaluate the feasibility of 2D-Perfusion Angiography (2D-PA) for objective, quantitative treatment response assessment in CMI. Read More

JACC Case Rep 2022 May 4;4(9):543-548. Epub 2022 May 4.

Mohammed Bin Khalifa Specialist Cardiac Centre (MKCC), Awali, Kingdom of Bahrain.

Hydrophilic polymers are frequently used as surface coatings in modern intravascular technologies. We hereby present a case of a patient who underwent transcatheter aortic valve implantation that was complicated with foot gangrene and mesenteric ischemia, necessitating emergency enterectomy. Histologic examination revealed hydrophilic polymer emboli as the culprit of these complications. Read More

Gastroenterology Res 2022 Apr 12;15(2):100-105. Epub 2022 Mar 12.

Department of Internal Medicine, Saint Francis Presence Hospital, Evanston, IL, USA.

Venous thromboembolism (VTE) is a recognized extraintestinal manifestation of inflammatory bowel disease (IBD), with deep venous thrombosis (DVT) and pulmonary embolism being reported as the most frequent vascular complications in IBD patients. Much less frequently, arterial thromboembolic events may also be associated with greater morbidity and mortality. Aortic mural thrombosis is a rare phenomenon described in patients with IBD that often results in serious consequences such as visceral infarction and acute ischemia of the lower extremities. Read More

Can Assoc Radiol J 2022 05 11:8465371221094280. Epub 2022 May 11.

Department of Diagnostic Radiology, University of Manitoba, Winnipeg, MB, Canada

Acute mesenteric ischemia (AMI) is an uncommon yet highly lethal cause of acute abdomen in the emergency setting. Computed tomography (CT) imaging, in particular a biphasic protocol consisting of angiographic and venous phase scans, is widely used to corroborate non-specific clinical findings when suspicions of AMI are high. Techniques such as low kilovoltage peak scanning, dual energy acquisition, or a combined arterial/enteric phase can improve iodine conspicuity and evaluation of bowel enhancement. Read More

Pediatr Res 2022 May 5. Epub 2022 May 5.

Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.

Background: Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with postnatal age, but normal ranges are not well defined.

Methods: A prospective study of ELBW preterm infants utilized NIRS monitoring to assess changes in cerebral and mesenteric saturation (Csat and Msat) over the first week after birth. Read More

Br J Hosp Med (Lond) 2022 Apr 6;83(4):1-8. Epub 2022 Apr 6.

Division of Emergency Medicine, Far East Rand Hospital, University of the Witwatersrand, South Africa.

Most life-threatening conditions form a coherent clinical picture, with examination findings confirming the patient's history. However, pain out of proportion to examination findings can also signify an emergency - acute compartment syndrome, bowel ischaemia, necrotising fasciitis and acute aortic dissection may all present in this way. A lack of situational awareness leads doctors to erroneously rely on examination findings to flag impending catastrophe, but in such cases misdiagnosis or delayed treatment can have dire consequences. Read More

Cureus 2022 Apr 27;14(4):e24532. Epub 2022 Apr 27.

Coronary Care Unit, National Institute of Cardiology, Mexico City, MEX.

Infective endocarditis (IE) can be complicated by systemic embolization. Unfortunately, in some situations, it requires radical and urgent therapeutic approaches. Herein, we describe a case of IE complicated by acute mesenteric ischemia (AMI) due to septic embolism prior to emergent cardiac surgery. Read More

Clin Res Hepatol Gastroenterol 2022 Apr 30:101932. Epub 2022 Apr 30.

Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany. Electronic address:

Despite one of the largest vaccination campaigns in human history, the COVID-19 pandemic has not been yet defeated. More than 10 billion doses of COVID-19 vaccine have been administered worldwide. AstraZeneca's Vaxzevria (ChAdOx1 nCoV-19 / AZD1222) was approved as the first viral vector-based vaccine in the EU on 29 January 2021. Read More

Vasc Endovascular Surg 2022 May 3:15385744221085382. Epub 2022 May 3.

Division of Vascular Surgery, Department of Surgery, McMaster UniversityRINGGOLD, Burlington, ON, Canada.

Objectives: Heavy cannabis use has been associated with the development of acute myocardial infarction and stroke. The objective of this study was to determine if heavy, chronic cannabis use is associated with the development of acute limb ischemia (ALI) or critical limb ischemia (CLI).

Methods: We conducted a retrospective cohort study within the National Inpatient Sample (2006-2015). Read More

Clin J Gastroenterol 2022 Apr 30. Epub 2022 Apr 30.

Pathology Division, Chiba-Ken Saiseikai Narashino Hospital, Social Welfare Organization Saiseikai Imperial Gift Foundation, Narashino, Japan.

Mesenteric phlebosclerosis is a rare form of intestinal ischemia characterized by thickening of the right-sided colon and calcification of the mesenteric vein. We describe the case of a 58-year-old woman admitted to our hospital because of abdominal pain and distension. An abdominal computed tomography study revealed remarkable dilatation and fluid collection of the small intestine compatible with intestinal obstruction, which was considered to be the result of stenosis of the ascending colon. Read More

J Card Surg 2022 Apr 30. Epub 2022 Apr 30.

Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.

Objective: This systematic review aims to identify predictors of outcomes of mesenteric ischemia in patients following cardiac surgery.

Methods: A comprehensive literature search was done on EMBASE, PubMed, Ovid MEDLINE, and SCOPUS using keywords relating to bowel ischemia and cardiac surgery. Database search results were screened by at least two authors and 32 articles were selected for inclusion in this review. Read More

Ulus Travma Acil Cerrahi Derg 2022 Apr;28(4):403-410

Department of General Surgery, Necmettin Erbakan University Meram Faculty of Medicine, Konya-Turkey.

Background: Acute mesenteric ischemia (AMI) is a rarely observed acute abdominal disease that may be mortal and is difficult to diagnose early. The aim of our study is to assess the role of Thiol-Disulphide Haemostasis (TDH), a new method for AMI which still has no specific biochemical markers for early diagnosis, and to assess it together with Ischemia-Modified Albumin (IMA) which has previously proven reliability for AMI.

Methods: The study included 32 Wistar albino rats in four groups. Read More

Ultraschall Med 2022 Apr 28. Epub 2022 Apr 28.

Internal Medicine, Albertinen Hospital, Hamburg, Germany.

Purpose:  Hepatic portal venous gas (HPVG) is a rare clinical finding, often caused by a severe underlying disease. In the literature as well as in clinical practice, HPVG is considered "signum malum" with a poor prognosis and bowel ischemia as the most common cause. Most studies are based on the results of computed tomography (CT) examinations. Read More

Eur J Vasc Endovasc Surg 2022 Apr 25. Epub 2022 Apr 25.

Institute of Clinical Medicine, University of Tartu, Tartu, Estonia; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

Cureus 2022 Apr 18;14(4):e24251. Epub 2022 Apr 18.

General Surgery Department, Imam Abdulrahman Alfaisal Hospital, Riyadh, SAU.

Introduction Superior mesenteric artery syndrome (SMAS), also called mesenteric duodenal compression syndrome, Wilkie's syndrome, chronic duodenal ileus or cast syndrome, is a rare clinical condition defined as a compression of the third portion of the duodenum in between the SMA and abdominal aorta (AA), due to narrowing of the space between them. SMAS is primarily attributed to loss of the intervening mesenteric fat pad, leading to partial or complete duodenal obstruction. Its manifestations are complex and non-specific, including postprandial epigastric pain, nausea, vomiting, early satiety, weight loss and anorexia. Read More

Clin Case Rep 2022 Apr 20;10(4):e05714. Epub 2022 Apr 20.

Department of Surgery JA Onomichi General Hospital Onomichi City Japan.

This case report describes a patient with nonocclusive mesenteric ischemia that developed due to diabetic ketoacidosis. We believe that early diagnosis and intervention may improve the prognosis of nonocclusive mesenteric ischemia that has low vascular risk, with the major risk factor being dehydration due to diabetic ketoacidosis. Read More

Ann Vasc Surg 2022 Apr 22. Epub 2022 Apr 22.

SCPMG Department of Research & Evaluation, Pasadena, CA.

Background: COVID-19 was initially identified as an acute respiratory disease, but it was quickly recognized that multiple organ systems could be affected. Venous thrombosis and pulmonary embolism have been well reported. However, there is a paucity of data on COVID-19-related arterial thrombosis. Read More

J Thorac Cardiovasc Surg 2022 Mar 26. Epub 2022 Mar 26.

Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan.

Objectives: We aimed to examine the incidence, etiologies, and consequences of acute mesenteric ischemia as well as the impact of preprocedural subclinical mesenteric artery stenosis in patients undergoing transcatheter aortic valve replacement.

Methods: Among prospective follow-up of 269 consecutive patients undergoing transcatheter aortic valve replacement, diagnosis of acute mesenteric ischemia was confirmed by abdominal computed tomography. Cumulative hazard of 1-year all-cause and cardiovascular mortality according to the absence or presence of mesenteric artery stenosis 70% or greater from preprocedural computed tomography angiography was analyzed. Read More

Intensive Care Med 2022 Apr 25. Epub 2022 Apr 25.

Direttore UOC di Anestesia Rianimazione e Terapia Intensiva Ospedale CTO Azienda Ospedali Dei Colli, Napoli, Italy.

Cureus 2022 Mar 9;14(3):e23013. Epub 2022 Mar 9.

Internal Medicine, Centro Hospitalar Tâmega e Sousa, Penafiel, PRT.

The coronavirus disease 2019 (COVID-19) disease is a multisystem disease and recent studies have shown an increase in reported thromboembolic complications as deep venous thrombosis, pulmonary embolism (PE), stroke, and less frequently mesenteric artery thrombosis. We present a case of a 75-year-old woman, COVID-19 positive with five days of evolution, who was admitted to the emergency room due to diffuse abdominal pain with several days of progression, along with diarrhea and biliary vomit. Abdominal computed tomography presented images of subtraction of the lumen of the upper mesenteric artery. Read More

J Med Cases 2022 Apr 25;13(4):188-191. Epub 2022 Mar 25.

South East Regional Hospital, Bega, NSW, Australia.

Pneumatosis cystoides intestinalis (PCI) is an uncommon condition where cyst-like locules of gas are present in the submucosa or subserosa of the gastrointestinal tract. The majority of cases are benign and are associated with drugs such as chemotherapy agents or conditions including chronic obstructive airways disease. We present the case of PCI resulting in pneumoperitoneum in a 72-year-old male patient on chemotherapy for esophageal adenocarcinoma. Read More

Acta Radiol Open 2022 Apr 18;11(4):20584601221094826. Epub 2022 Apr 18.

Department of Radiology, Rigshospitalet, Copenhagen, Denmark.

In this case report, we outline a tailored approach for a complex patient with acute in chronic proximal occlusive mesenteric disease complicated with fresh thrombosis and a heavily calcified aorta, where the standard treatment proved suboptimal. We outline the surgical considerations that ultimately led to performing a hybrid procedure of open thrombectomy combined with retrograde open mesenteric stenting of the superior mesenteric artery. The patient was a 75-year-old male, with a history of severe arteriosclerosis presenting with abdominal pain over 48 h. Read More

Int J Surg Case Rep 2022 Apr 18;94:107088. Epub 2022 Apr 18.

Department of Surgery, Shinko Hospital, 1-4-47 Wakihama-cho, Chuo-ku, Kobe City, Hyogo 651-0072, Japan.

Introduction: Evaluation of anatomical variations is important in pancreatoduodenectomy (PD) because an arterial anomaly is a risk factor for morbidity. Herein, we report a rare case of PD for lower bile duct cancer in which celiac axis stenosis and a replaced common hepatic artery (rCHA) coexisted.

Presentation Of Case: An 84-year-old woman presented with epigastric pain. Read More

J Thorac Cardiovasc Surg 2022 Mar 31. Epub 2022 Mar 31.

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pa; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa. Electronic address:

Diagnostics (Basel) 2022 Mar 29;12(4). Epub 2022 Mar 29.

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

A significant proportion of patients with COVID-19 pneumonia could develop acute respiratory distress syndrome (ARDS), thus requiring mechanical ventilation, and resulting in a high rate of intensive care unit (ICU) admission. Several complications can arise during an ICU stay, from both COVID-19 infection and the respiratory supporting system, including barotraumas (pneumothorax and pneumomediastinum), superimposed pneumonia, coagulation disorders (pulmonary embolism, venous thromboembolism, hemorrhages and acute ischemic stroke), abdominal involvement (acute mesenteric ischemia, pancreatitis and acute kidney injury) and sarcopenia. Imaging plays a pivotal role in the detection and monitoring of ICU complications and is expanding even to prognosis prediction. Read More

J Card Surg 2022 Apr 21. Epub 2022 Apr 21.

General Surgery Department, Heart, Vascular and Thoracic Institute, Cleveland Clinic Florida, Weston, Florida, USA.

Extracorporeal membrane oxygenation (ECMO) has been adopted to support patients with acute severe cardiac or pulmonary failure that is potentially reversible and unresponsive to conventional management. Mesenteric ischemia (MI) can present as a life-threatening complication in patients receiving veno-arterial echocardiogram (ECHO) support. Due to the nature and acuity of these conditions, determining adequate perfusion upon surgical intervention is challenging for the operating surgeon, especially in cardiogenic shock (CS) patients on ECMO support persenting low arterial pulsatility. Read More