Biochem Biophys Res Commun 2022 05 7;603:138-143. Epub 2022 Mar 7.
Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, and Biomedical Research Institute, Hubei University of Medicine, Hubei, China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, and Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei University of Medicine, Hubei, China. Electronic address:
Schistosoma japonicum is a parasitic worm that lives in the mesenteric vein of its host and feeds on blood, suggesting that it might be a natural resource of novel anticoagulants. Here, by comprehensive analyses of the genomic sequences of Schistosoma japonicum, a new Kunitz-type gene precursor was identified. The Kunitz-type gene precursor codes for an 18-residue signal peptide and a 60-residue mature peptide. Read More