Phylodynamics of Merkel-cell polyomavirus and Human polyomavirus 6: a long-term history with humans.
- Carolina Torres,
- Melina Elizabeth Barrios,
- Robertina Viviana Cammarata,
- Matías Victoria,
- Xavier Fernandez-Cassi,
- Silvia Bofill-Mas,
- Rodney Colina,
- María Dolores Blanco Fernández,
- Viviana Andrea Mbayed
Mol Phylogenet Evol 2018 Apr 19. Epub 2018 Apr 19.
Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología. Buenos Aires, Argentina; CONICET, Buenos Aires, Argentina.
New human polyomaviruses have been described in the last years, including the Merkel-cell polyomavirus (MCPyV; Human polyomavirus 5) and the Human polyomavirus 6 (HPyV6). Although their infection is usually asymptomatic, in immunocompromised host can cause life-threatening pathologies, such as the Merkel cell carcinoma, an aggressive skin neoplasia associated to the MCPyV. Despite being prevalent viruses in population, epidemiological data from South America are scarce, as well as the characterization of the viral types circulating and their origin. Read More