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Injury 2020 May 23. Epub 2020 May 23.

Department of Orthopaedics, Hanil General Hospital, 308 Uicheon-ro, Dobong-Gu, Seoul 132-703, Republic of Korea. Electronic address:

Background: Femoral nerve palsy caused by iliacus hematoma is an infrequent diagnosis often missed because of its insidious presentation. However, due to potentially devastating outcomes, prompt recognition and management are essential.

Objectives: The aim with this study was to better characterize clinical presentation, diagnosis, treatment, and prognosis of iliacus hematoma. Read More

Surg Radiol Anat 2020 May 22. Epub 2020 May 22.

Department of Anatomy, Research Institute of Medical Science, Konkuk University School of Medicine, 120 Neungdong-ro, Gwangjin-gu, Seoul, 05029, Republic of Korea.

The iliacus muscle is a large, flat, triangle-shaped muscle located in the iliac fossa. This muscle forms part of the iliopsoas muscle complex. Although anatomical variations of iliacus muscles are rare, some variations are clinically important due to the possible coexistence of an unusual course of the femoral nerve. Read More

Orthop Surg 2020 May 18. Epub 2020 May 18.

Department of Orthopaedic Surgery, Amphia Hospital, Breda, The Netherlands.

Objectives: To assess the learning curve of the direct superior approach (DSA) for total hip arthroplasty (THA) and to compare surgical, clinical, and radiological results with a matched control group using the mini posterior approach (MPA).

Methods: A prospective cohort study was performed from October 2016 to May 2017 including our first 52 patients undergoing THA using the DSA. Patients with primary osteoarthritis or osteonecrosis and a body mass index (BMI) < 35 who were eligible for surgery were included. Read More

Orthop Traumatol Surg Res 2020 May 11. Epub 2020 May 11.

Department II of Orthopaedics, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders; China International Science and Technology Cooperation base of Child development and Critical Disorders, the Children's Hospital of Chongqing Medical University, Yuzhong District Zhongshan 2road 136#, 400014 Chongqing, China. Electronic address:

Introduction: There is some debate over the best treatment for anterior-superior iliac spine (ASIS) avulsion fractures, although non-surgical treatment can achieve the same results as open surgery.

Hypothesis: Absorbable screws can be safely used for ASIS avulsion fractures in children and adolescents.

Aim Of The Study: Here, we compared patients on whom no surgery was performed with those who underwent open surgery and investigated the feasibility of using absorbable screws as a new fixation material for treating ASIS avulsion fractures in children and adolescents. Read More

J Clin Rheumatol 2020 May 9. Epub 2020 May 9.

Rheumatology Department, Hospital Universitario de Móstoles.

Muscle Nerve 2020 Jun 17;61(6):788-791. Epub 2020 Apr 17.

Department of Neurology, Haga Hospital, The Hague, The Netherlands.

Background: Meralgia paresthetica is a mononeuropathy of the lateral femoral cutaneous nerve. A common therapy is injection with corticosteroids. The goal of this study was to analyze the effect of injection with methylprednisolone/lidocaine vs placebo. Read More

Case Rep Neurol Med 2020 10;2020:2352850. Epub 2020 Mar 10.

Neurology Department, Sunderland Royal Hospital, South Tyneside & Sunderland NHS Foundation Trust, Sunderland, UK.

Background: Bilateral femoral neuropathy is an uncommon complication of various surgical and nonsurgical procedures, such as pelvic/abdominal surgery or vaginal delivery. . We report a case of a 41-year-old male who was found unresponsive against the wall in a "lithotomy-type" position with both knees flexed at approximately 90 degrees and both hips flexed and externally rotated at approximately 90 and 60 degrees, respectively, 24-48 hours after a drug overdose (combination of dihydrocodeine, paracetamol, diazepam, and amitriptyline). Read More

Rinsho Ketsueki 2020 ;61(3):262-267

Department of Hematology and Oncology, Dokkyo Medical University Hospital.

A 70-year-old woman experienced pain in both gastrocnemius muscles, numbness in the toes, and muscle weakness in both the legs that lasted for two months. After getting admitted to our hospital, the muscle weakness extended to both her arms, and nerve conduction studies revealed decreased nerve conduction velocity, which was more prominent in the elbow and the axilla than in the wrist. A magnetic resonance imaging revealed a tumor in the right femoral neck, which was histologically diagnosed as plasmacytoma. Read More

J Neurosurg 2020 Mar 20:1-2. Epub 2020 Mar 20.

Neuromodulation 2020 Mar 18. Epub 2020 Mar 18.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.

Objective: Peripheral nerve stimulation via multi-contact nerve cuff electrodes (NCEs) has proved effective in restoring function to individuals with lower-extremity paralysis. This study investigates clinical measures of nerve health over one year post-implantation of a composite flat-interface nerve electrode (C-FINE) on the tibial and peroneal nerves above the knee in a human volunteer. This represents the first deployment of a novel NCE on new neural targets in a uniquely challenging location prone to prolonged externally applied forces, making acute and chronic postoperative observation critical. Read More

Indian J Hematol Blood Transfus 2020 Jan 24;36(1):174-177. Epub 2019 Jun 24.

Department of Internal Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01608 USA.

Hematomas in close compartments and in pelvic gutters are always challenging to treat and diagnose. A young female on apixaban for recently diagnosed pulmonary thromboembolism (PE) presented to us for the complaints of right sided lower limb weakness. Neurological examination was positive for the right femoral nerve distribution deficit. Read More

Obstet Gynecol Surv 2020 Feb;75(2):121-126

Associate Professor, Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR.

Importance: Carpal tunnel syndrome and meralgia paresthetica are 2 common neuropathies complicating pregnancy. Each of these causes significant discomfort but can be diagnosed and treated safely during pregnancy.

Objective: This article outlines the existing literature diagnosis, treatment, and prognosis of carpal tunnel syndrome and meralgia paresthetica, specifically looking at the implications during pregnancy. Read More

J Biol Res (Thessalon) 2020 Dec 18;27. Epub 2020 Feb 18.

Laboratory of Histology and Embryology, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

Background: Bisphosphonates (BPs) are forceful inhibitors of osteoclast-mediated bone resorption. Long-term BP use is associated with multiple rare but severe adverse effects. The objective of this study was to investigate the possible effects of BPs in the structure of femoral nerve. Read More

Skeletal Radiol 2020 Jul 24;49(7):1135-1140. Epub 2020 Feb 24.

Department of Radiology, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA.

Objective: Identify sonographic features of the lateral femoral cutaneous nerve (LFCN) in meralgia paresthetica (MP) and report therapeutic outcomes in sonographically confirmed cases.

Materials And Methods: Retrospective review of 50 patients with clinically suspected MP and 20 controls. Ultrasounds were reviewed for characteristics of the LFCN and compared between groups. Read More

Radiol Case Rep 2020 Apr 12;15(4):424-426. Epub 2020 Feb 12.

Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland.

We present the case of a 17 year old football player with a 2 week history of left leg weakness and difficulty weight-bearing. Magnetic resonance imaging revealed a well-circumscribed lesion deep to the left iliacus muscle. The patient proceeded to computed tomography-guided biopsy. Read More

Am J Ophthalmol Case Rep 2020 Mar 25;17:100606. Epub 2020 Jan 25.

Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, MN, USA.

Purpose: We detail a case of cobalt toxicity with visual and systemic complications, review the pathogenic process for the optic neuropathy and retinopathy, and discuss the controversy of metallic hip prosthesis.

Observations: A 59-year-old female with a history of multiple left hip arthroplasties presented to our clinic with bilateral visual loss. The year prior, she had failure of the hip implant necessitating revision surgery with placement of a chrome-cobalt head. Read More

Pain Med 2020 Feb 5. Epub 2020 Feb 5.

Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

Background: Meralgia paresthetica is a term used to describe a clinical pain syndrome related to the compression or irritation of the lateral femoral cutaneous nerve (LFCN). The LFCN is a pure sensory nerve that is susceptible to compression injury. The most common compression locations are: as it courses from the lumbosacral plexus, through the abdominal cavity, under the inguinal ligament, and into the subcutaneous tissue of the thigh. Read More

Br J Radiol 2020 Apr 29;93(1108):20190556. Epub 2020 Jan 29.

Dra. Roca Diagnóstico Médico. CEMEDI, Carrera del Sábado, 4, 50006, Zaragoza, Spain.

Objective: Anatomical analysis of the hips and pelvis was performed using MRI to evaluate morphological characteristics and associations between them. We identified correlations between the ischiofemoral space (IFS), quadratus femoris space (QFS), femoral version angle (FVA) and cervicodiaphyseal angle (CDA).

Methods: This study involved a retrospective search of a database of consecutive reports of adult hip MRI examinations carried out between January and September 2016. Read More

Calcif Tissue Int 2020 Apr 13;106(4):355-363. Epub 2020 Jan 13.

Department of Ultrasound, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, 107 West Yanjiang Road, Guangzhou, 510120, China.

Microvascular complications are prevalent in patients with type 2 diabetes mellitus (T2DM), resulting in increased risk of cardiovascular mortality. However, it is unclear whether above-knee artery calcification relates to microvascular complications. This study was aimed to investigate the role of calcification in superficial femoral arteries (SFA), the major above-knee artery, compared with anterior tibial arteries (ATA) and posterior tibial arteries (PTA), in T2DM-related microvascular complications and explore its risk factors. Read More

Am J Emerg Med 2019 Dec 24. Epub 2019 Dec 24.

Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, United States of America. Electronic address:

As many as 5% of patients using oral anticoagulants suffer from a major bleeding event annually. Spontaneous retroperitoneal hemorrhage is a rare but serious complication, with a mortality rate as high as 20%. Oral anticoagulants were responsible for 2. Read More

Rom J Morphol Embryol 2019 ;60(3):955-961

Department of Rheumatology, University of Medicine and Pharmacy of Craiova, Romania;

Behçet's disease is a multi-systemic vasculitis of small arteriolar and venular vessels, which shows a wide range of clinical manifestations, such as oral and genital aphthosis, erythema nodosum, panuveitis, complex gastrointestinal disorders, the early onset of neurological involvement being a negative prognostic factor in evolution. We present the case of a 36-year-old patient, who was admitted in the Clinic of Rheumatology for recurrent-neglected oral aphthosis, recurrent erythema nodosum, left hip pain, reduction of visual acuity of the right eye, weight loss, profuse sweating, marked fatigability. From the personal history was retained avascular necrosis of right femoral head, with arthroplasty at this level, human leukocyte antigen-B51 (HLA-B51) positive. Read More

Exp Gerontol 2020 Mar 31;131:110799. Epub 2019 Dec 31.

Alejalil Hospital, Aq Qala, Golestan, Iran.

Diabetic peripheral neuropathy (DPN) is associated with peripheral arterial disease and endothelial dysfunction. We investigated the effect of exercise training on the measures of superficial femoral artery (SFA) and neuropathic symptoms in patients with DPN. In a randomized-controlled trial, 31 volunteers with established DPN were randomly assigned to experimental or control groups. Read More

BMJ Case Rep 2019 Dec 29;12(12). Epub 2019 Dec 29.

Obstetrics & Gynaecology, Rotunda Hospital, Dublin, Ireland.

A 34-year-old primiparous woman presented in spontaneous labour and had an unassisted vaginal birth of a 3.5 kg infant. Postnatally, the patient experienced lower limb weakness and was unable to mobilise unassisted. Read More

Pain Pract 2020 Jun 6;20(5):566-567. Epub 2020 Feb 6.

Department of Physical Medicine and Rehabilitation, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.

SA J Radiol 2019 21;23(1):1745. Epub 2019 Aug 21.

Department of Radiology, University of Pretoria, Pretoria, South Africa.

Meralgia paresthetica is a neuropathy of the lateral femoral cutaneous nerve. Traditionally, the diagnosis is based on classical symptoms and signs. In cases where there is a diagnostic dilemma, the role of magnetic resonance imaging has been to exclude other causes for the patient's presentation, as the small extraspinal peripheral nerves were not well visualised at imaging. Read More

Turk Neurosurg 2020 ;30(1):89-93

Eskisehir City Hospital, Department of Neurosurgery, Eskisehir, Turkey.

Aim: To investigate the incidence, risk factors, and recovery of patients with meralgia paresthetica (MP) following posterior spine surgery.

Material And Methods: Patients who underwent posterior spine surgeries in prone position at the authors’ clinics were included in this study. Patients with preoperative MP were excluded. Read More

World Neurosurg 2020 Feb 13;134:e885-e891. Epub 2019 Nov 13.

Spine Care Institute, Hospital for Special Surgery, New York, New York, USA.

Background: Lateral lumbar interbody fusion (LLIF) has often been associated with postoperative lumbar plexus symptoms, including pain, paresthesia, and motor deficits in the lower extremities, especially the anterior thigh regions. Previous studies have suggested that LLIF procedures at L4-L5 will be associated with a greater motor deficit rate than other levels. However, it is unclear which level has the greatest risk of pain and paresthesia. Read More

J Vasc Surg 2020 May 4;71(5):1538-1545. Epub 2019 Nov 4.

Department of Vascular Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Objective: The majority of endovascular aneurysm repair procedures are performed through the common femoral artery (CFA). Arterial access is gained by surgical cutdown or percutaneous approach. The surgical approach has a relatively high local complication rate. Read More

Zhonghua Wai Ke Za Zhi 2019 Nov;57(11):878-880

Department of Spine Surgery, Fuzhou Second Hospital Affiliated to Xiamen University, Fuzhou 350007, China.

Meralgia paresthetica (MP) after posterior spine surgery is caused by mechanical compression injury of lateral femoral cutaneous nerve, which presents as numbness or paresthesia in the confined area of the anterolateral thigh. MP after posterior spine surgery is a common postoperative complication, and the incidence is 12.7%-25. Read More

Arthroscopy 2019 10;35(10):2825-2831

Department of Orthopaedic Surgery, University of Utah, Salt Lake City, Utah, U.S.A.. Electronic address:

Purpose: To (1) evaluate the individual and combined effects of traction time and traction force on postoperative neuropathy following hip arthroscopy, (2) determine if perioperative fascia iliaca block has an effect on the risk of this neuropathy, and (3) identify if the these items had a significant association with the presence, location, and/or duration of postoperative numbness.

Methods: Between February 2015 and December 2016, a consecutive cohort of hip arthroscopy patients was prospectively enrolled. Traction time, force, and postoperative nerve block administration were recorded. Read More

Postgrad Med 2020 Jan 6;132(1):1-6. Epub 2019 Oct 6.

Lecturer at the Department of Anatomy, Faculty of Medicine, Maranatha Christian University, Bandung, Indonesia.

Meralgia Paresthetica (MP) is one of the most common mononeuropathies of the lower limb. MP usually resolves on its own, even without treatment. However, many physicians are not aware of this diagnosis and may confuse patients with another nerve disease such as radiculopathies. Read More

Pain Physician 2019 09;22(5):E505-E510

Guizhou Provincial People's Hospital.

Background: Diabetes is one of the most common diseases in today's society. Diabetes can cause multiple vascular lesions in the body, renal insufficiency, blindness, and so on. However, the evidence concerning the role of extracorporeal shock wave therapy in diabetic vascular disease is insufficient. Read More

Int Med Case Rep J 2019 31;12:243-247. Epub 2019 Jul 31.

Internal Medicine Clinic, Bainbridge, NY 13733, USA.

Background: Peripheral neuropathy is a common complication of Lyme disease. Cranial mononeuropathy, particularly that affecting the facial nerve, can be a presenting symptom, and at times, it can be associated with polyradiculopathies or plexopathies. However, isolated femoral neuropathy has not yet been reported in Lyme disease; therefore, we felt the need to present this case. Read More

Equine Vet J 2020 May 1;52(3):359-363. Epub 2019 Oct 1.

Department of Small Animal Clinical Sciences, Texas A&M University College of Veterinary Medicine and Biomedical Sciences, College Station, Texas, USA.

Background: Pelvic limb neuropathy is a rare post-anaesthetic complication. In the authors' experiences, the incidence of post-anaesthesia neuropathy is increased following MRI of the proximal metatarsus and tarsal regions when compared with previously reported incidences of post-anaesthetic neuropathy.

Objectives: This study reports the incidence, diagnosis, treatment and outcome of seven horses with post-anaesthesia neuropathy following proximal metatarsal and tarsal MRI. Read More

Top Companion Anim Med 2019 Sep 25;36:1-3. Epub 2019 Apr 25.

Small Animal Surgery, Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science - São Paulo State University (UNESP), Botucatu, SP, Brazil.

This study aimed to evaluate femoral nerve latency time recorded from both vastus lateralis and vastus medialis muscles, in clinically healthy dogs. Eighteen adult dogs were distributed into 2 distinct body mass ranges (Group 1: 1-4.1 kg, n= 9; Group 2: 4. Read More

J Pharm Pharmacol 2019 Nov 29;71(11):1706-1713. Epub 2019 Aug 29.

Department of Geriatric Endocrinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Objectives: Emerging evidence showed that muscone could improve chronic inflammation after myocardial infarction and protect alcohol-induced osteonecrosis of the femoral head. However, the function of muscone on diabetic peripheral neuropathy (DPN) is obscure.

Methods: The neuronal Schwann cell RSC 96 cells were treated with 125 mmol/l glucose to simulate the cells in DPN. Read More

Am J Phys Med Rehabil 2019 Aug 6. Epub 2019 Aug 6.

Department of Physical Medicine and Rehabilitation, Istanbul University Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Turkey.

Case Rep Surg 2019 9;2019:7085219. Epub 2019 Jul 9.

Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Iliacus compartment syndrome is a rare clinical condition which can result in a severe, unilateral, femoral neuropraxia. Recognition of this syndrome as the cause of a developing neuropathy is often delayed given a lack of familiarity with this clinical diagnosis and the retroperitoneal location of the iliacus muscle. Prompt diagnosis is important to avoid risk of consequent muscle necrosis, rhabdomyolysis, and possibly permanent nerve injury. Read More

Ann Indian Acad Neurol 2019 Jul-Sep;22(3):308-310

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Meralgia paresthetica (MP) is a painful mononeuropathy of the lateral femoral cutaneous nerve. It is usually idiopathic and can be treated with drugs used for neuropathic pain such as pregabalin, gabapentin, and amitriptyline.

Objectives: This study was done to study the effect of triamcinolone acetonide on drug refractory MP. Read More

Rev Esp Geriatr Gerontol 2020 Mar - Apr;55(2):120-122. Epub 2019 Jul 25.

Servicio de Geriatría, Hospital Nuestra Señora de Gracia, Zaragoza, España.

75-year-old patient with a history of acenocumarol anticoagulated atrial fibrillation, which shows pain, functional impotence and right lower limb paresthesias after fall. Studies evidenc evertebral fracture L5 and haematoma on right iliac muscle, proceeding to surgical drainage, suspension of acenocumarol, and onset of apixaban. After treatment persisted femoral neuropathy, which not allowed complete functional recovery. Read More

J Foot Ankle Surg 2019 Nov 23;58(6):1267-1272. Epub 2019 Jul 23.

Associate Professor, Department of Anatomy, Western University of Health Sciences College of Osteopathic Medicine of the Pacific and College of Podiatric Medicine, Pomona, CA.

The area of skin supplied by the cutaneous branch of the obturator nerve (CBO) is highly variable. Although most introductory anatomy texts describe the CBO as innervating only a portion of the medial thigh, there are numerous reports in the literature of CBOs passing the knee to innervate the proximal, middle, or even distal leg. There are no previous reports of CBOs extending to the ankle and foot. Read More

Neurol India 2019 May-Jun;67(3):928-929

Department of Nursing and Medicine, Federal University of Viçosa, Minas Gerais, Brazil.

HeartRhythm Case Rep 2019 Jun 19;5(6):317-320. Epub 2019 Mar 19.

Department of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

J Surg Oncol 2020 Jan 22;121(1):182-186. Epub 2019 Jun 22.

Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, California.

This is a case report of a 68-year-old male with stage III right lower extremity lymphedema following right inguinal lymph node dissection and adjuvant chemoradiotherapy for Hodgkin's lymphoma. He developed peripheral neuropathy and radiation-induced right femoral artery thrombosis, treated with saphenous vein graft. He underwent three vascularized lymph node transfers (VLNTs) to the upper medial thigh, posterior calf, and ankle with placement of nanofibrillar collagen scaffolds. Read More

J Clin Neurosci 2019 Sep 18;67:40-45. Epub 2019 Jun 18.

Adnan Menderes University, Medical Faculty, Department of Neurosurgery, Aydin, Turkey.

A common entrapment site of the lateral femoral cutaneous nerve (LFCN) is in the vicinity of the inguinal ligament. However the more distal segment of this nerve can also be affected. Electrophysiological evaluation of this nerve is difficult. Read More

Semin Musculoskelet Radiol 2019 Jun 4;23(3):e58-e67. Epub 2019 Jun 4.

IRCCS Istituto Ortopedico Galeazzi, Milano Italy.

Pain around the hip and pelvis is a very common condition. Pain may be generated within the joint space (i.e. Read More

Asian Spine J 2019 10 3;13(5):721-729. Epub 2019 Jun 3.

Department of Orthopedic and Spine Surgery, Apollo Hospitals, Bilaspur, India.

Study Design: Prospective study.

Purpose: To verify the feasibility and safety of outpatient microscopic lumbar discectomy (MLD) in a developing country.

Overview Of Literature: Outpatient MLD is advantageous in terms of cost effectiveness and avoidance of nosocomial infections. Read More

Inflammopharmacology 2019 Aug 22;27(4):713-722. Epub 2019 May 22.

Department of Anesthesiology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 289, Jianguo Rd., Sindian District, New Taipei City, 23142, Taiwan.

Vasculitic peripheral neuropathy (VPN) is characterized by acute-to-subacute onset of painful sensory and motor disturbances that result from inflammatory obliteration of nerve blood vessels and subsequent ischaemic injury. Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of various peripheral neuropathies, and 4-phenylbutyric acid (4-PBA) is a chemical chaperone that inhibits ER stress signaling. We investigated the effects of 4-PBA on neuropathic pain associated with VPN induced by ischaemia-reperfusion (IR) and its underlying mechanisms. Read More

PLoS One 2019 20;14(5):e0217068. Epub 2019 May 20.

Department of Rehabilitation Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

Nerve palsy following total hip arthroplasty (THA) can have a serious effect on a patient`s functional prognosis and on cost-effectiveness, and it is the leading cause of THA-associated medical litigation. However, only a few studies focus on femoral nerve palsy (FNP) following THA with the direct anterior approach (DAA). Moreover, several studies have reported that THA with DAA may result in higher complication rates, particularly during the so-called 'learning-curve period' for the surgeon. Read More