221 results match your criteria Mental Disorders Secondary to General Medical Conditions


A regionally specific drinking custom 'Otōri' and its association with alcohol consumption/alcohol use disorders: a cross-sectional study.

BMJ Open 2021 05 13;11(5):e041738. Epub 2021 May 13.

Division of Clinical Epidemiology, Research Center for Medical Sciences, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.

Objectives: The primary objective was to describe the characteristics of Otōri, a regionally specific drinking custom in the Miyakojima region of Okinawa, Japan, and its participants. The secondary objective was to clarify the distribution of alcohol consumption/alcohol use disorders as measured by the Alcohol Use Disorders Identification Test (AUDIT) and its association with the frequency of engagement in Otōri per month.

Design: Cross-sectional study. Read More

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Prevalence of depression and anxiety in people with inflammatory bowel disease and associated healthcare use: population-based cohort study.

Evid Based Ment Health 2021 Mar 30. Epub 2021 Mar 30.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Inflammatory bowel disease (IBD) has a significant impact on quality of life for many people.

Objective: To assess the prevalence of common mental health conditions in IBD and the combined impact of IBD and mental health conditions on healthcare use and time off work.

Methods: A UK population-based primary care database (Royal College of General Practitioners Research and Surveillance Centre) was used to identify adults with IBD (n=19 011) (Crohn's disease (CD) or ulcerative colitis (UC)), and matched controls (n=76 044). Read More

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Artificial intelligence-assisted phenotype discovery of fragile X syndrome in a population-based sample.

Genet Med 2021 Mar 26. Epub 2021 Mar 26.

Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.

Purpose: Fragile X syndrome (FXS), the most prevalent inherited cause of intellectual disability, remains underdiagnosed in the general population. Clinical studies have shown that individuals with FXS have a complex health profile leading to unique clinical needs. However, the full impact of this X-linked disorder on the health of affected individuals is unclear and the prevalence of co-occurring conditions is unknown. Read More

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Blended Acceptance and Commitment Therapy Versus Face-to-face Cognitive Behavioral Therapy for Older Adults With Anxiety Symptoms in Primary Care: Pragmatic Single-blind Cluster Randomized Trial.

J Med Internet Res 2021 Mar 26;23(3):e24366. Epub 2021 Mar 26.

Faculty of Social and Behavioural Sciences, Section of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, Netherlands.

Background: Anxiety symptoms in older adults are prevalent and disabling but often go untreated. Most trials on psychological interventions for anxiety in later life have examined the effectiveness of face-to-face cognitive behavioral therapy (CBT). To bridge the current treatment gap, other treatment approaches and delivery formats should also be evaluated. Read More

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A Multi-Method Approach to a Comprehensive Examination of the Psychiatric and Neurological Consequences of Intimate Partner Violence in Women: A Methodology Protocol.

Front Psychiatry 2021 19;12:569335. Epub 2021 Feb 19.

The Translational Research Center for Traumatic Brain Injury and Stress Disorders and the Geriatric Research, Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, MA, United States.

The number of women in the United States that experience blows to the head during assaults by intimate partners is substantial. The number of head blows that result in a traumatic brain injury (TBI) is virtually unknown, but estimates far exceed numbers of TBI in parallel populations (e.g. Read More

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February 2021

Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study.

Lancet Digit Health 2021 04 18;3(4):e217-e230. Epub 2021 Feb 18.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Health Data Research UK, London, UK.

Background: There are concerns that the response to the COVID-19 pandemic in the UK might have worsened physical and mental health, and reduced use of health services. However, the scale of the problem is unquantified, impeding development of effective mitigations. We aimed to ascertain what has happened to general practice contacts for acute physical and mental health outcomes during the pandemic. Read More

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Psychiatric disorders in adults with cerebral palsy.

Res Dev Disabil 2021 Apr 29;111:103859. Epub 2021 Jan 29.

Faculty of Health Sciences, University of Ontario Institute of Technology, Oshawa, ON, L1H 7K4, Canada.

Background: Cerebral palsy (CP) is one of the most common neurological conditions in childhood. Individuals with CP often experience various secondary conditions, including intellectual disability (ID), medical conditions, and psychiatric issues. A large number of youth with CP have psychiatric disorders; however, few studies have examined the prevalence of psychiatric issues in adults with CP at the population-level. Read More

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Briquet syndrome revisited: implications for functional neurological disorder.

Brain Commun 2020 23;2(2):fcaa156. Epub 2020 Sep 23.

Functional Neurology Research Group, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

With the creation of the Somatic Symptom and Related Disorders category of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition in 2013, the functional neurological (symptom) disorder diagnostic criteria underwent transformative changes. These included an emphasis on 'rule-in' physical examination signs/semiological features guiding diagnosis and the removal of a required proximal psychological stressor to be linked to symptoms. In addition, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition somatization disorder, somatoform pain disorder and undifferentiated somatoform disorder conditions were eliminated and collapsed into the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition somatic symptom disorder diagnosis. Read More

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September 2020

Depressive symptoms and cardiovascular disease: a population-based study of older adults in rural Burkina Faso.

BMJ Open 2020 12 22;10(12):e038199. Epub 2020 Dec 22.

Heidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.

Objectives: To contribute to the current understanding of depressive disorders in sub-Saharan African (SSA) countries by examining the association of depressive symptoms with cardiovascular and cardiometabolic conditions in a population-based study of middle-aged and older adults in rural Burkina Faso.

Setting: This study was conducted in the Nouna Health and Demographic Surveillance System in north-western Burkina Faso, in a mixed rural and small-town environment. The data were obtained between May and July 2018. Read More

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December 2020

Trauma-focused psychodynamic therapy and STAIR Narrative Therapy of post-traumatic stress disorder related to childhood maltreatment: trial protocol of a multicentre randomised controlled trial assessing psychological, neurobiological and health economic outcomes (ENHANCE).

BMJ Open 2020 12 17;10(12):e040123. Epub 2020 Dec 17.

Institute of Clincal Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.

Introduction: Success rates of psychotherapy in post-traumatic stress disorder related to childhood maltreatment (PTSD-CM) are limited.

Methods And Analysis: Observer-blind multicentre randomised clinical trial (A-1) of 4-year duration comparing enhanced methods of STAIR Narrative Therapy (SNT) and of trauma-focused psychodynamic therapy (TF-PDT) each of up to 24 sessions with each other and a minimal attention waiting list in PTSD-CM. Primary outcome is severity of PTSD (Clinician-Administered PTSD Scale for DSM-5 total) assessed by masked raters. Read More

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December 2020

Factors associated with the mental health status of medical students during the COVID-19 pandemic: a cross-sectional study in Japan.

BMJ Open 2020 12 10;10(12):e043728. Epub 2020 Dec 10.

Department of Medical Education, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.

Objective: The COVID-19 pandemic had a substantial impact on university students, including those in medical schools, with disruption in routine education causing significant psychological distress. The objective of this study was to evaluate the factors associated with psychological distress among medical students during the period of enforced home quarantine from March through May 2020.

Design: A cross-sectional study. Read More

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December 2020

Association of Social Media Use With Mental Health Conditions of Nonpatients During the COVID-19 Outbreak: Insights from a National Survey Study.

J Med Internet Res 2020 12 31;22(12):e23696. Epub 2020 Dec 31.

School of Communication, East China Normal University, Shanghai, China.

Background: Considerable research has been devoted to examining the mental health conditions of patients with COVID-19 and medical staff attending to these patients during the COVID-19 pandemic. However, there are few insights concerning how the pandemic may take a toll on the mental health of the general population, and especially of nonpatients (ie, individuals who have not contracted COVID-19).

Objective: This study aimed to investigate the association between social media use and mental health conditions in the general population based on a national representative sample during the peak of the COVID-19 outbreak in China. Read More

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December 2020

Risk of First General Hospital Admissions for Self-Harm Among People With Personality Disorder: A Retrospective Cohort Study.

J Pers Disord 2020 Oct 27:1-S6. Epub 2020 Oct 27.

Department of Psychological Medicine (King's College London), Institute of Psychiatry, Psychology, and Neuroscience, London, UK.

For individuals with a personality disorder (PD), it is unknown whether additional psychiatric conditions increase their risk of self-harm. The authors therefore conducted a retrospective cohort study, using data from secondary mental health care, to identify self-harm admissions. Adults with diagnosed PD, followed up over a 6-year period, were involved ( = 7,475). Read More

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October 2020

Changes in Cigarette Consumption With Reduced Nicotine Content Cigarettes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage: 3 Randomized Clinical Trials.

JAMA Netw Open 2020 10 1;3(10):e2019311. Epub 2020 Oct 1.

UVM Tobacco Center of Regulatory Science, University of Vermont, Burlington.

Importance: This study is part of a programmatic effort evaluating the effects of reducing nicotine content of cigarettes to minimally addictive levels.

Objective: To examine whether very low-nicotine-content (VLNC) cigarettes decrease smoking rates and dependence severity among smokers with psychiatric disorders or socioeconomic disadvantage.

Design, Setting, And Participants: These 3 randomized clinical trials were performed at the University of Vermont, Brown University, and Johns Hopkins University between October 2016 and September 2019. Read More

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October 2020

Schema therapy versus cognitive behavioral therapy versus individual supportive therapy for depression in an inpatient and day clinic setting: study protocol of the OPTIMA-RCT.

BMC Psychiatry 2020 10 14;20(1):506. Epub 2020 Oct 14.

Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, 80804, Munich, Germany.

Background: Major depressive disorder represents (MDD) a major cause of disability and disease burden. Beside antidepressant medication, psychotherapy is a key approach of treatment. Schema therapy has been shown to be effective in the treatment of psychiatric disorders, especially personality disorders, in a variety of settings and patient groups. Read More

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October 2020

Exploring how people with dementia can be best supported to manage long-term conditions: a qualitative study of stakeholder perspectives.

BMJ Open 2020 10 8;10(10):e041873. Epub 2020 Oct 8.

Division of Psychiatry, University College London, London, UK.

Objectives: To explore how the self-management of comorbid long-term conditions is experienced and negotiated by people with dementia and their carers.

Design: Secondary thematic analysis of 82 semi-structured interviews.

Setting: Community settings across the United Kingdom. Read More

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October 2020

Diagnosis of physical and mental health conditions in primary care during the COVID-19 pandemic: a retrospective cohort study.

Lancet Public Health 2020 10 23;5(10):e543-e550. Epub 2020 Sep 23.

The National Institute for Health Research Greater Manchester Patient Safety Translational Research Centre, University of Manchester, Manchester, UK; Division of Informatics, Imaging and Data Science, University of Manchester, Manchester, UK.

Background: To date, research on the indirect impact of the COVID-19 pandemic on the health of the population and the health-care system is scarce. We aimed to investigate the indirect effect of the COVID-19 pandemic on general practice health-care usage, and the subsequent diagnoses of common physical and mental health conditions in a deprived UK population.

Methods: We did a retrospective cohort study using routinely collected primary care data that was recorded in the Salford Integrated Record between Jan 1, 2010, and May 31, 2020. Read More

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October 2020

Prevalence of psychoactive substance use among acutely hospitalised patients in Oslo and Moscow: a cross-sectional, observational study.

BMJ Open 2020 09 17;10(9):e032572. Epub 2020 Sep 17.

Department of Forensic Sciences, Oslo University Hospital, Oslo, Norway.

Objectives: The use of psychoactive prescription medication is increasing in the general population. This is a cause for concern, particularly among the elderly, where physiological changes related to senescence increase the risk for adverse effects. While previous studies regarding psychoactive substance use have generally been population based, we sought to determine the frequency of such use among acutely hospitalised patients. Read More

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September 2020

Positive and negative experiences of caregiving in dementia: The role of sense of coherence.

Int J Geriatr Psychiatry 2021 02 25;36(2):360-367. Epub 2020 Sep 25.

Department of Psychiatry, University of Santiago de Compostela (USC), Santiago de Compostela, Spain.

Objectives: Sense of coherence (SOC) is increasingly recognized as an important health determinant, particularly for mental health. Part of the evidence comes from informal caregivers in diverse clinical conditions. The extent to which SOC influences caregiving outcomes, however, is relatively under-researched in dementia, particularly regarding positive experiences. Read More

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February 2021

Common infections, mental health problems and healthcare use in people with inflammatory bowel disease: a cohort study protocol.

Evid Based Ment Health 2021 05 17;24(2):82-87. Epub 2020 Sep 17.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

Introduction: People with inflammatory bowel disease (IBD) are at increased risk of pneumonia and herpes zoster, yet other common infection types have not been explored. Anxiety and depression are more prevalent in IBD; however, the impact of these conditions on primary care healthcare use in IBD is not known.

Methods And Analysis: We will perform two retrospective studies using a large English population-based primary care cohort to compare the following outcomes in people with IBD and matched controls: incident infections (Study 1) and prevalent mental health problems and healthcare use, overall and in those with and without mental health problems (Study 2). Read More

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Prevalence and outcome of delirium among acute general medical inpatients in Cape Town, South Africa.

S Afr Med J 2020 May 29;110(6):519-524. Epub 2020 May 29.

Division of General Medicine, Department of Medicine, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, South Africa.

Background: Delirium is a common, serious, underdiagnosed condition in medical and surgical inpatients with acute conditions. It is associated with increased risk of mortality and morbidity. Data of geriatric cohorts are largely limited to developed countries. Read More

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Whole Health Action Management: A Randomized Controlled Trial of a Peer-Led Health Promotion Intervention.

Psychiatr Serv 2020 10 25;71(10):1039-1046. Epub 2020 Aug 25.

Center on Mental Health Services Research and Policy, Department of Psychiatry, University of Illinois at Chicago, Chicago (Cook, Jonikas, Burke-Miller, Hamilton, Wolfgang); Appalachian Consulting Group, Cleveland, Georgia (Powell, Fricks); Georgia Mental Health Consumer Network, Atlanta (Tucker); Blue Cross Blue Shield of Illinois, Chicago (Weidenaar); Howard Brown Health, Chicago (Morris); Women's Treatment Center, Chicago (Powers).

Objective: Adults with serious mental illness have high rates of general medical comorbidity and encounter challenges in dealing with multiple health conditions. Chronic illness self-management programs may help them more effectively cope with comorbid illnesses, especially when instructors are certified peer specialists. This study assessed the longitudinal effectiveness of a peer-delivered health promotion program. Read More

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October 2020

Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders.

Int J Neuropsychopharmacol 2021 Apr;24(4):256-313

Service of Interdisciplinary Neuromodulation, Laboratory of Neurosciences (LIM-27), Department and Institute of Psychiatry & Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.

Background: Transcranial direct current stimulation has shown promising clinical results, leading to increased demand for an evidence-based review on its clinical effects.

Objective: We convened a team of transcranial direct current stimulation experts to conduct a systematic review of clinical trials with more than 1 session of stimulation testing: pain, Parkinson's disease motor function and cognition, stroke motor function and language, epilepsy, major depressive disorder, obsessive compulsive disorder, Tourette syndrome, schizophrenia, and drug addiction.

Methods: Experts were asked to conduct this systematic review according to the search methodology from PRISMA guidelines. Read More

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Opinions, Attitudes, and Perceptions in Relation to Erectile Dysfunction and Premature Ejaculation in the Undiagnosed Spanish Male Population. Results of the PANDORA Project.

J Sex Med 2020 08 1;17(8):1495-1508. Epub 2020 Jul 1.

Adelphi Spain, Barcelona, Spain.

Background: Approximately 43% of Spanish men report experiencing premature ejaculation (PE) at some point in their lives and 12.1% suffer from erectile dysfunction (ED), of whom only 16.5% have seen a doctor. Read More

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Sahaj Samadhi Meditation versus a Health Enhancement Program for depression in chronic pain: protocol for a randomized controlled trial and implementation evaluation.

Trials 2020 Apr 7;21(1):319. Epub 2020 Apr 7.

Bridgepoint Collaboratory for Research and Innovation, Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON, Canada.

Background: Despite the high prevalence of comorbid chronic pain and depression, this comorbidity remains understudied. Meditation has demonstrated efficacy for both chronic pain and depression independently, yet there have been few studies examining its effectiveness when both conditions are present concurrently. Furthermore, while meditation is generally accepted as a safe and effective health intervention, little is known about how to implement meditation programs within or alongside the health care system. Read More

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Area deprivation, urbanicity, severe mental illness and social drift - A population-based linkage study using routinely collected primary and secondary care data.

Schizophr Res 2020 06 2;220:130-140. Epub 2020 Apr 2.

HDRUK, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK; National Centre for Mental Health, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff CF24 4HQ, UK. Electronic address:

We investigated whether associations between area deprivation, urbanicity and elevated risk of severe mental illnesses (SMIs, including schizophrenia and bipolar disorder) is accounted for by social drift or social causation. We extracted primary and secondary care electronic health records from 2004 to 2015 from a population of 3.9 million. Read More

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MANAGEMENT OF ENDOCRINE DISEASE: Female sexual dysfunction for the endocrinologist.

Eur J Endocrinol 2020 Jun;182(6):R101

Chair in Endocrinology and Medical Sexology (ENDOSEX), Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

Sexual function is an important component of either general health and quality of life in both genders. Many studies have focused on the different risk factors for sexual dysfunctions, proving an association with several medical conditions. Endocrine disorders have been often mentioned in the pathogenesis of female and male sexual dysfunctions; however, particularly in women, sexual function is rarely addressed during clinical, in general, and endocrinological, in particular, consultations. Read More

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Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.

JAMA Psychiatry 2020 07;77(7):755-765

Institute of Psychiatry and Mental Health, Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Centro de Investigación Biomédica en Red Salud Mental (CIBERSAM), Madrid, Spain.

Importance: Detection, prognosis, and indicated interventions in individuals at clinical high risk for psychosis (CHR-P) are key components of preventive psychiatry.

Objective: To provide a comprehensive, evidence-based systematic appraisal of the advancements and limitations of detection, prognosis, and interventions for CHR-P individuals and to formulate updated recommendations.

Evidence Review: Web of Science, Cochrane Central Register of Reviews, and Ovid/PsychINFO were searched for articles published from January 1, 2013, to June 30, 2019, to identify meta-analyses conducted in CHR-P individuals. Read More

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Effectiveness of the Extension for Community Health Outcomes Model as Applied to Primary Care for Autism: A Partial Stepped-Wedge Randomized Clinical Trial.

JAMA Pediatr 2020 05 4;174(5):e196306. Epub 2020 May 4.

Department of Child Health, University of Missouri, Columbia.

Importance: The Extension for Community Health Outcomes (ECHO) model is a widely adopted technology-based model for training primary care physicians and practitioners (PCPs) to care for patients with complex conditions. Despite its popularity, to our knowledge, direct effects of ECHO on clinical practice have not been tested in a large-scale study.

Objective: To test the effectiveness of the ECHO model as applied to primary care for autism and whether it resulted in improved clinical practice, knowledge, and self-efficacy regarding autism screening and comorbidity management. Read More

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Protocol for a multi-site study of the effects of overdose prevention education with naloxone distribution program in Skåne County, Sweden.

BMC Psychiatry 2020 02 7;20(1):49. Epub 2020 Feb 7.

Department of Clinical Sciences, Psychiatry, Faculty of Medicine, Lund University, Lund, Sweden.

Background: Continuously high rates of overdose deaths in Sweden led to the decision by the Skåne County to initiate the first regional take-home naloxone program in Sweden. The project aims to study the effect of overdose prevention education and naloxone distribution on overdose mortality in Skåne County. Secondary outcome measures include non-fatal overdoses and overdose-related harm in the general population, as well as cohort-specific effects in study participants regarding overdoses, mortality and retention in naloxone program. Read More

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February 2020