5,640 results match your criteria Menorrhagia


Thrombin generation during a regular menstrual cycle in women with von Willebrand disease.

Sci Rep 2018 Nov 30;8(1):17467. Epub 2018 Nov 30.

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Fluctuations of the sex steroids during the menstrual cycle might significantly influence hemostasis. This association, derived from a number of the observations on healthy women, is yet to be described in females affected by bleeding disorders. The aim of the current study was to assess the changes in hemostatic variables in women with vWD during two phases of the menstrual cycle (follicular and luteal) and to compare it with healthy controls. Read More

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November 2018

The Adolescent with Menorrhagia: Diagnostic Approach to a Suspected Bleeding Disorder.

Pediatr Rev 2018 Dec;39(12):588-600

Department of Pediatrics, Holtz Children's Hospital-Jackson Memorial Medical Center, Miami, FL.

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December 2018

Evaluation of the Effect of Uterine Fibroids on Microwave Endometrial Ablation Profiles.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:3236-3239

Thermal ablation of the endometrial lining of the uterus is a minimally-invasive technique for treatment of menorrhagia. We have previously presented a 915 MHz microwave triangular loop antenna for endometrial ablation. Uterine fibroids are benign pelvic tumors, of considerably different water content compared to normal uterus, and may change the shape of the uterus. Read More

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[Additional non-contraceptive effects of contraception: CNGOF Contraception Guidelines].

Gynecol Obstet Fertil Senol 2018 Nov 7. Epub 2018 Nov 7.

Service de gynécologie-obstétrique, CHRU de Nancy, 10, avenue du Dr-Heydenreich, 54035 Nancy, France. Electronic address:

Hormonal and intrauterine contraceptive methods provide women with highly efficient protection against undesired pregnancy. Additional non-contraceptive effects are now well documented. Combined hormonal contraceptives use, either through the oral transdermal and vaginal route, allow a reduction in menorrhagia, dysmenorrhea, functional ovarian cysts, benign breast and uterine disease, endometriosis-related pain and recurrence. Read More

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November 2018
4 Reads

Diagnosis and Management of an Adenomatoid Uterine Tumor: Ultrasound, Magnetic Resonance Imaging, Surgical Appearance, and Pathology Correlation.

Biores Open Access 2018 26;7(1):159-164. Epub 2018 Oct 26.

Department of Obstetrics and Gynecology and Texas Tech University Health Sciences Center, Lubbock, Texas.

Adenomatoid uterine tumors are rare, and their appearance on medical imaging modalities is not well established. We present a case of an adenomatoid uterine tumor reviewing a unique sonographic presentation, magnetic resonance imaging (MRI), gross surgical appearance of the tumor, and microscopic pathology images. A 29-year-old gravida 0 Caucasian woman presented with dysmenorrhea, menorrhagia, and desire to conceive. Read More

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October 2018
2 Reads

Correlation of LOX‑5 and COX‑2 expression with inflammatory pathology and clinical features of adenomyosis.

Mol Med Rep 2018 Nov 1. Epub 2018 Nov 1.

Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China.

Adenomyosis is a common benign disease of women of childbearing age. The typical clinical features are prolonged menstruation, menorrhagia and ingravescent dysmenorrhea. In the present study, the severity of dysmenorrhea was assessed using the visual analogue scale system as follows: 0, No pain; 1‑3, minimal pain; 4‑6, moderate pain; and 7‑10, severe pain. Read More

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November 2018
3 Reads

RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis.

J Int Med Res 2018 Nov 2:300060518789038. Epub 2018 Nov 2.

3 Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: This study aimed to investigate RhoA, RhoA-associated coiled-coil containing protein kinase (ROCK) 1, ROCK2, and Rho GTPase-activating protein 26 (ARHGAP26) expression in the eutopic endometrium (EU) and ectopic endometrium (EC), and examine their relationships with the clinical characteristics of adenomyosis.

Methods: Twenty patients with adenomyosis who underwent laparoscopy were recruited. Protein and mRNA expression of RhoA, ROCK1, ROCK2, and ARHGAP26 in EU and EC of patients with adenomyosis and in control endometrium without adenomyosis (CE) was detected. Read More

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November 2018
2 Reads

Naturopathic Medicine for the Management of Endometriosis, Dysmenorrhea, and Menorrhagia: A Content Analysis.

J Altern Complement Med 2018 Oct 31. Epub 2018 Oct 31.

1 Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney , Ultimo, New South Wales, Australia .

Objectives: To explore the recommendations of naturopathic medicine for the management of endometriosis, dysmenorrhea, and menorrhagia, drawing on traditional and contemporary sources.

Design: Content analysis.

Setting: Australia, Canada, and the United States of America (USA). Read More

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October 2018
2 Reads

Early vaginal replacement in cloacal malformation.

Pediatr Surg Int 2018 Oct 30. Epub 2018 Oct 30.

Department of Pediatric Surgery, All India Institute of Medical Sciences, Room no. 4001-2, Ansari Nagar, New Delhi, 110029, India.

Purpose: We assessed the surgical outcome of cloacal malformation (CM) with emphasis on need and timing of vaginal replacement.

Methods: An ambispective study of CM was carried out including prospective cases from April 2014 to December 2017 and retrospective cases that came for routine follow-up. Early vaginal replacement was defined as that done at time of bowel pull through. Read More

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October 2018
8 Reads
1.060 Impact Factor

Frequency of presentation and characteristics of chronic pelvic pain at the gynecologic consultation

Rev Med Inst Mex Seguro Soc 2018 10 25;56(3):226-230. Epub 2018 Oct 25.

Instituto Mexicano del Seguro Social, Hospital de Gineco Obstetricia No.4 “Luis Castelazo Ayala”, División de Investigación en Salud. Ciudad de México, México

Background: Chronic pelvic pain (CPP) is a condition characterized by recurring pain in the lower part of the abdomen and it lasts at least six months.

Objective: To know the frequency and characteristics of CPP in women from the gynecology consultation.

Methods: Women that consecutively attended the gynecology external consultation were questioned about the presence of CPP. Read More

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October 2018
1 Read

Predisposing factors for predicting the therapeutic response of adenomyosis after uterine artery embolization: serum CA125 levels and accompanying endometriosis.

Diagn Interv Radiol 2018 Nov;24(6):364-371

Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Purpose: We aimed to identify predisposing factors that could help predict the therapeutic response of adenomyosis after uterine artery embolization (UAE).

Methods: This was a retrospective, single-center study of patients admitted to the hospital for adenomyosis between 2013 and 2015. Sixty-eight patients with adenomyosis who underwent UAE with tris-acryl gelatin microspheres were divided into two groups based on their therapeutic response (complete or incomplete necrosis of lesions), and pre- and postprocedural pelvic magnetic resonance imaging (MRI) data. Read More

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November 2018
6 Reads

Weak correlation of bleeding scores to platelet electron microscopy: A retrospective chart review of pediatric patients with delta-storage pool disorder.

Pediatr Blood Cancer 2018 Oct 21:e27505. Epub 2018 Oct 21.

Department of Pediatric Hematology Oncology, University of California-Davis, Davis, California.

Background: Delta granule storage pool deficiency (δ-SPD) is a rare platelet disorder in which a deficiency of platelet granules leads to poor aggregation, resulting in varying clinical bleeding phenotypes. Children with δ-SPD have variable laboratory results, making the proper diagnosis and evaluation controversial.

Objectives: To describe the demographic and laboratory trends of this population and to assess the value of electron microscopy in diagnostic evaluation and its correlation to bleeding symptoms. Read More

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October 2018
4 Reads

Increased LDH5/LDH1 ratio in preoperative diagnosis of uterine sarcoma with inconclusive MRI and LDH total activity but suggestive CT scan: a case report.

BMC Womens Health 2018 Oct 19;18(1):169. Epub 2018 Oct 19.

Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.

Background: Morcellation of undiagnosed uterine sarcoma is cause of abdominal/pelvic dissemination, residual tumor and recurrence. In the preoperative evaluation of suspect uterine masses, magnetic resonance imaging (MRI) and serum lactate dehydrogenase (LDH) total activity are referred to as the most effective tools, while computed tomography scan (CT) and LDH isoenzymes are less considered in literature.

Case Presentation: A 46 year old woman was admitted to our department with a large uterine mass. Read More

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October 2018
4 Reads
1.660 Impact Factor

Ethnopharmacology, phytochemistry, and pharmacology of Sterculia lychnophora Hance (Pangdahai).

Chin J Nat Med 2018 Oct;16(10):721-731

Tianjin State Key Laboratory of Modern Chinese Medicine and School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. Electronic address:

The matured, ripen, and dried seeds of Scaphium affine (Mast.) Pierre, known as Pangdahai (PDH) in Chinese and recorded as Sterculia lychnophora Hance (scientific synonym) in the 2015 edition of the Chinese Pharmacopeia, have been widely used in traditional Chinese medicine, Japanese folk medicine, Vietnamese traditional medicine, traditional Thai medicine and Indian traditional medicine. The decoctions of the seeds are used as a remedy for pharyngitis, laryngitis, constipation, cough, menorrhagia, and pain management. Read More

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October 2018
11 Reads

Successful pregnancies in women with diffuse uterine leiomyomatosis after hysteroscopic management using the Hysteroscopy Endo Operative system.

J Minim Invasive Gynecol 2018 Oct 8. Epub 2018 Oct 8.

Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:

Study Objective: To evaluate the feasibility, effectiveness, and reproductive outcome of hysteroscopic management using the Hysteroscopy Endo Operative system (HEOS) in patients with diffuse uterine leiomyomatosis (DUL).

Design: Retrospective study (Canadian Task Force Classification III).

Setting: Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Read More

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October 2018
6 Reads

The rescue effect of adalimumab in the treatment of refractory pediatric panuveitis complicated with steroid-induced glaucoma.

Taiwan J Ophthalmol 2018 Jul-Sep;8(3):164-167

Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan.

We report the rescue effects of adalimumab (HUMIRA) therapy in a case of refractory pediatric panuveitis complicated with steroid-induced glaucoma. A 13-year-old girl had suffered from blurred vision since January 2013. Bilateral idiopathic panuveitis with macular edema (ME) was diagnosed. Read More

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October 2018
9 Reads

Burkitt Lymphoma Presenting as Menorrhagia and a Vaginal Mass in an Adolescent.

J Pediatr Adolesc Gynecol 2018 Sep 29. Epub 2018 Sep 29.

Division of Gynecology, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts. Electronic address:

Background: Menorrhagia is a common gynecologic complaint among adolescents, which rarely is secondary to malignancy. Burkitt lymphoma can mimic gynecologic malignancy, however it is rarely seen in adolescents. Burkitt lymphoma of the gynecologic tract requires early diagnosis and intervention for optimal outcomes. Read More

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September 2018
10 Reads

Adenolipoleiomyoma Polyp of the Uterus: A Case Report and Review of the Literature.

Case Rep Pathol 2018 6;2018:5704382. Epub 2018 Sep 6.

Pathology Department, Erasme University Hospital, Université Libre de Bruxelles, CP 610, Route de Lennik 808, 1070 Brussels, Belgium.

Adenolipoleiomyoma is a very rare lesion of the uterus. Only four cases were reported. We describe one case of adenolipoleiomyoma presenting as a polyp in a postmenopausal woman with menorrhagia. Read More

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September 2018

Transvaginal Natural Orifice Transluminal Endoscopic Surgery Hysterectomy in a Woman with Uterine Adenomyosis and Multiple Severe Abdominal Adhesions.

Gynecol Minim Invasive Ther 2018 Apr-Jun;7(2):70-73. Epub 2018 May 2.

Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan.

Natural orifice transluminal endoscopic surgery (NOTES) had been used for many gynecologic surgeries without pelvic adhesions. We report a 30-year-old female with multiple abdominal adhesions underwent NOTES hysterectomy successfully. A 30-year-old female (para 2, gravida 3, abortus 1) presented with menorrhagia and dysmenorrhea. Read More

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May 2018
6 Reads

Effectiveness of bipolar impedance controlled radiofrequency (NovaSure) endometrial ablation for the treatment of menorrhagia in Hong Kong Chinese women.

Gynecol Minim Invasive Ther 2017 Oct-Dec;6(4):186-190. Epub 2017 Jul 31.

Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong.

Objective: Bipolar impedance controlled radiofrequency endometrial ablation is a valuable treatment options for menorrhagia. We examined the short term outcomes of Hong Kong Chinese women undergone this procedure.

Material: All patients who underwent this procedure at Queen Elizabeth Hospital, Hong Kong during January 2013 to August 2016. Read More

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July 2017
1 Read

Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women.

J Womens Health (Larchmt) 2018 Nov 19;27(11):1359-1367. Epub 2018 Sep 19.

5 Allergan PLC, Madison, New Jersey.

Background: Most women will experience uterine fibroids by the age of 50, yet few data exist describing the overall patient experience with fibroids. The objective of this population-based survey was to characterize symptom burden, patient awareness, and treatment decision-making for fibroids, including a comparison among women of varying backgrounds.

Materials And Methods: Women (≥18 years) were recruited via email from GfK KnowledgePanel, a representative panel of US households, or identified with opt-in consumer panels. Read More

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November 2018
19 Reads

A Rare Case of Cyclical Hemothorax: Thoracic Endometriosis Syndrome.

Case Rep Pulmonol 2018 19;2018:9830797. Epub 2018 Aug 19.

Department of Medicine, Charleston Area Medical Center, Charleston, WV, USA.

Endometriosis is a common condition in which endometrial cells and stroma are deposited in extrauterine sites. Its prevalence has been estimated to be 10% of reproductive age females. It is commonly found in the pelvis; however, it may be found in the abdomen, thorax, brain, or skin. Read More

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August 2018
1 Read

The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions.

Int J Gynaecol Obstet 2018 Dec 10;143(3):393-408. Epub 2018 Oct 10.

School of Women's and Children's Health, Royal Hospital for Women, University of New South Wales, Randwick, NSW, Australia.

Background: The International Federation of Gynecology and Obstetrics (FIGO) systems for nomenclature of symptoms of normal and abnormal uterine bleeding (AUB) in the reproductive years (FIGO AUB System 1) and for classification of causes of AUB (FIGO AUB System 2; PALM-COEIN) were first published together in 2011. The purpose was to harmonize the definitions of normal and abnormal bleeding symptoms and to classify and subclassify underlying potential causes of AUB in the reproductive years to facilitate research, education, and clinical care. The systems were designed to be flexible and to be periodically reviewed and modified as appropriate. Read More

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December 2018
47 Reads

Factor VII deficiency - an enigma; clinicohematological profile in 12 cases.

Hematology 2019 Dec 7;24(1):97-102. Epub 2018 Sep 7.

a Department of Hematology , All India Institute of Medical Sciences , New Delhi , India.

Objective: Factor VII deficiency is the commonest of the rare bleeding disorders with limited knowledge on clinical profile. The objective of this study was to study the prevalence and clinico-hematological profile of factor VII-deficient patients.

Methods: It is a retrospective observational study of probable inherited factor VII deficiency covering 18 months. Read More

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December 2019
6 Reads
1.190 Impact Factor

Safety Profile of Levonorgestrel: A Disproportionality Analysis of Food and Drug Administration Adverse Event Reporting System (Faers) Database.

J Reprod Infertil 2018 Jul-Sep;19(3):152-156

Department of Community Medicine, M.S. Ramaiah Medical College, Bangalore, India.

Background: Levonorgestrel is most commonly utilized as an emergency oral contraceptive. Little is known and/or studied about the adverse effects of levonorgestrel, therefore, current investigation was aimed to generate signal for unreported adverse drug reactions of levonorgestrel using disproportionality analysis in food and drug administration adverse events reporting system database.

Methods: In FDA Adverse Events Reporting System (FAERS) database, all adverse event reports for levonorgestrel between January 2006 to June 2015 were identified and disproportionality analysis was conducted for selected adverse events of levonorgestrel using Reporting Odds Ratio, Proportional Reporting Ratio and Information Component with 95% confidence interval. Read More

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September 2018
7 Reads

An Unusual Case of Deep Vein Thrombosis After Orthognathic Surgery: A Case Report and Review of the Literature.

J Oral Maxillofac Surg 2018 Jul 30. Epub 2018 Jul 30.

Member of Kerman Dental and Oral Diseases Research Center; Associate Professor, Department of Oral Medicine, Dental School, Kerman University of Medical Science, Kerman, Iran. Electronic address:

Deep vein thrombosis (DVT) is caused primarily by obstruction of blood flow in the deep veins in the lower limbs. It is a form of thrombophlebitis and can be a major cause of morbidity and mortality in hospitalized patients. This report describes an unusual case of DVT in a 21-year-old woman with Class III malocclusion who underwent bimaxillary orthognathic surgery (bilateral sagittal split osteotomy and Le Fort I osteotomy) under general anesthesia. Read More

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July 2018
3 Reads

Adenoma Malignum of the Uterine Cervix: A Case Report.

Mymensingh Med J 2018 Jul;27(3):654-657

Dr Md Sadrul Amin, Associate Professor, Department of Radiology & Imaging, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:

Adenoma malignum (AM) of the uterine cervix, otherwise known as minimal deviation adenocarcinoma, is a rare variant of cervical adenocarcinoma, which represents a diagnostic challenge, due to its benign-resembling histological characteristics. We present a case of 54-year-old nullipara woman presented with menorrhagia for 2 years and that had worsened over the past few months. Transabdominal ultrasound fibroid uterus with cluster of nabothian cysts was in the cervix. Read More

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July 2018
1 Read

A systematic review of methods to measure menstrual blood loss.

BMC Womens Health 2018 Aug 22;18(1):142. Epub 2018 Aug 22.

Bayer AG, 13342, Berlin, Germany.

Background: Since the publication over 50 years ago of the alkaline hematin method for quantifying menstrual blood loss (MBL) many new approaches have been developed to assess MBL. The aim of this systematic review is to determine for methods of measuring MBL: ability to distinguish between normal and heavy menstrual bleeding (HMB); practicalities and limitations in the research setting; and suitability for diagnosing HMB in routine clinical practice.

Methods: Embase®™, MEDLINE®, and ClinicalTrials. Read More

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August 2018
22 Reads

How we treat the platelet glycoprotein defects; Glanzmann thrombasthenia and Bernard Soulier syndrome in children and adults.

Br J Haematol 2018 Sep 17;182(5):621-632. Epub 2018 Aug 17.

Department of Paediatric Haematology, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

The inherited platelet glycoprotein deficiencies, Glanzmann thrombasthenia (GT) and Bernard Soulier syndrome (BSS) are rare but important long-term bleeding disorders. Once diagnosed, affected patients should be referred to a specialist centre for bleeding disorders for general advice and ongoing management. Patients do not require prophylactic treatment and so the management of GT and BSS focuses around prophylactic treatment prior to high risk procedures and treatment in response to non-surgical bleeding events and, in women, the management of menorrhagia and pregnancy. Read More

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September 2018
2 Reads

Use of Uterine Characteristics to Improve Fertility-Sparing Diagnosis of Adenomyosis.

J Gynecol Surg 2018 Aug;34(4):183-189

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA.

To describe patient demographics, determine accuracy of clinical diagnosis, and evaluate reliability of laparoscopic uterine characteristics in the diagnosis of adenomyosis. Enrollment included 117 patients undergoing laparoscopic hysterectomy for benign indications. Intraoperatively, the attending surgeon predicted uterine weight; evaluated the presence of fibroids; and commented on the uterus' shape, color, and consistency while probing it with a blunt instrument. Read More

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August 2018
12 Reads

Significant gynecological bleeding in women with low von Willebrand factor levels.

Blood Adv 2018 Jul;2(14):1784-1791

National Coagulation Centre, St. James's Hospital, Dublin, Ireland.

Gynecological bleeding is frequently reported in women with von Willebrand disease (VWD). Low von Willebrand factor (VWF) may be associated with significant bleeding phenotype despite only mild plasma VWF reductions. The contribution of gynecological bleeding to this phenotype has yet to be described. Read More

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July 2018
4 Reads

A Prospective, Multicenter, Pivotal Trial to Evaluate the Safety and Effectiveness of the AEGEA Vapor Endometrial Ablation System.

J Minim Invasive Gynecol 2018 Jul 21. Epub 2018 Jul 21.

Stamford Health/Columbia University Medical School, Stamford, Connecticut (Dr. Chudnoff).

Study Objective: To evaluate the safety and effectiveness of the AEGEA Vapor System (Aegea Medical System, Menlo Park, CA) for the treatment of heavy menstrual bleeding (HMB).

Design: A prospective, multicenter, single-arm, open-label, clinical trial. Follow-up assessments were conducted at 24 hours; 2 weeks; and 3, 6, and 12 months after the endometrial ablation procedure (Canadian Task Force Classification II-1). Read More

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July 2018
2 Reads

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies.

Cochrane Database Syst Rev 2018 07 13;7:CD012534. Epub 2018 Jul 13.

Chair of Epidemiology and Preventive Medicine; Department of Hygiene and Dietetics; Systematic Reviews Unit - Polish Cochrane Branch, Jagiellonian University Medical College, Kopernika 7, Krakow, Poland, 31-034.

Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterised by the presence of antiphospholipid (aPL) antibodies that have prothrombotic activity. Antiphospholipid antibodies are associated with an increased risk of pregnancy complications (recurrent miscarriage, premature birth, intrauterine growth retardation) and thrombotic events (both arterial and venous). The most common thrombotic events include brain ischaemia (stroke or transient ischaemic attack) and deep vein thrombosis. Read More

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July 2018
12 Reads

Combination of microwave endometrial ablation and postoperative dienogest administration is effective for treating symptomatic adenomyosis.

J Obstet Gynaecol Res 2018 Sep 12;44(9):1787-1792. Epub 2018 Jul 12.

Fukushima Medical Center for Children and Women, Fukushima Medical University, Fukushima, Japan.

Aim: Menorrhagia and dysmenorrhea are common symptoms. Uterine adenomyosis is one of the causes of menorrhagia and dysmenorrhea. These symptoms often decrease the quality of life in women. Read More

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September 2018
12 Reads

Iron Deficiency Anemia with Menorrhagia: Ferric Carboxymaltose a Safer Alternative to Blood Transfusion.

J Midlife Health 2018 Apr-Jun;9(2):92-96

Department of Obstetrics and Gynaecology, Institute of Kidney Diseases and Research Centre, Ahmedabad, Gujarat, India.

Background: Menstrual disorder accounts for 5%-10% of the women presenting with iron deficiency anemia (IDA) in the perimenopausal age group. Heavy menstrual bleeding in this age group leads to severe anemia and frequently requires blood transfusion which has its own adverse effects. We today have ferric carboxymaltose (FCM) as a safer alternative to blood transfusion. Read More

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July 2018
6 Reads

Ryzophagia secondary to PCOS -related menorrhagia.

Med J Malaysia 2018 Jun;73(3):170-171

Borneo Medical Center, Department of Obstetrics & Gynaecology, Kuching, Sarawak, Malaysia.

We report the peculiar case of a patient who consumed raw rice daily and had iron-deficiency anaemia secondary to menorrhagia with underlying polycystic ovarian syndrome. A 32-year-old lady of Asian descent presented with symptoms of fatigue, lethargy and prolonged, irregular periods for the last two months. There was noticeable increase in body weight, male pattern alopecia and facial acne. Read More

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June 2018
8 Reads

Intravenous immunoglobulin for severe thrombocytopenia in secondary dengue.

BMJ Case Rep 2018 Jun 27;2018. Epub 2018 Jun 27.

Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.

A 30-year-old woman with severe dengue presented on the sixth day of her illness with life-threatening thrombocytopenia, refractory to multiple platelet transfusions. Dengue IgM antibody and the non-structural-1 antigen tests as of day 3 were negative. The IgG antibody against the same was positive, suggesting a past episode of dengue. Read More

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June 2018
10 Reads

Non-arteritic anterior ischaemic optic neuropathy secondary to menorrhagia in a young healthy woman.

BMJ Case Rep 2018 Jun 27;2018. Epub 2018 Jun 27.

Ophthalmology Department, Universiti Sains Malaysia - Health Campus, Kubang Kerian, Malaysia.

Non-arteritic anterior ischaemic optic neuropathy (NAION) may develop due to severe anaemia and hypotension which is seen in acute blood loss. The devastating visual loss is often irreversible. We report a case of NAION in a 20-year-old healthy woman, who presented on the third day of a heavy menstrual cycle with hypovolaemic shock. Read More

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Hematologic Considerations and Management of Adolescent Girls with Heavy Menstrual Bleeding and Anemia in US Children's Hospitals.

J Pediatr Adolesc Gynecol 2018 Oct 22;31(5):446-450. Epub 2018 Jun 22.

Division of Hematology/Oncology, Nationwide Children's Hospital, Columbus, Ohio; Department of Pediatrics, The Ohio State University, Columbus, Ohio.

Study Objective: To assess the frequency, severity, and inpatient management of girls admitted with heavy menstrual bleeding and iron deficiency anemia at US children's hospitals, with a focus on hematologic considerations.

Design: Retrospective multicenter cohort study from October 2012 through September 2015.

Setting: Children's hospitals submitting data to the Pediatric Health Information System. Read More

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October 2018
14 Reads

Endometrial Biopsy in an Outpatient Gynaecological Setting: Overinvestigation.

J Obstet Gynaecol Can 2018 Oct 21;40(10):1309-1314. Epub 2018 Jun 21.

Centre Hospitalier de l'Université de Montréal, Montréal, QC; Département d'obstétrique-gynécologie de l'Université de Montréal, Montréal, QC. Electronic address:

Objective: We reviewed the indications for endometrial biopsy at the general gynaecology outpatient clinic of the Université de Montréal Hospital Center and measured their compliance with the Society of Obstetricians and Gynaecologists of Canada and other international guidelines.

Methods: Three hundred and seventy-one files of patients who had an endometrial biopsy between January and October 2015 were reviewed. Indication for endometrial biopsy and pathology results were noted. Read More

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October 2018
2 Reads

Evaluation of Influencing Factors on Tubal Sterilization Regret: A Cross-Sectional Study.

Int J Fertil Steril 2018 Jun 20;12(3):200-206. Epub 2018 Jun 20.

Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Bachground: The aim of this study is to evaluate the menstrual pattern, sexual function, and anxiety, and depression in women with poststerilization regret, and potential influencing factors for regret following tubal ligation (TL) in Iranian women.

Materials And Methods: In this cross-sectional study, 166 women with TL were subdivided into two groups including women with poststerilization regret (n=41) and women without poststerilization regret (n=125). They were selected from a health care center in Guilan province (Iran) during 2015-2016. Read More

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June 2018
9 Reads

Primary breast cancer relapse as metastasis to the cervix uteri: A case report.

Mol Clin Oncol 2018 Jul 14;9(1):96-97. Epub 2018 May 14.

Oncology Unit, AP-HP - Hospital Beaujon, 92110 Clichy, France.

Metastasis of non-gynaecological tumours to the cervix is a rare event, and metastasis from breast cancer is even rarer, with only a limited number of such cases reported in the literature to date. We herein report the case of an 86-year-old female patient who had undergone mastectomy and axillary lymphadenectomy for invasive ductal cell breast carcinoma 2 years prior, followed by adjuvant hormonal therapy with letrozole. During hospitalization for anemia associated with an inflammatory syndrome and abdominal pain with menorrhagia, an abdominal ultrasound examination revealed a suspicious uterine mass with irregular contours and abnormal vascularization with associated increase of the blood level of cancer antigen 15-3 to 34 kU/l. Read More

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July 2018
3 Reads

Postpartum Intrauterine Device Refusal in Delhi: Reasons Analyzed.

J Obstet Gynaecol India 2018 Jun 14;68(3):208-213. Epub 2015 Jul 14.

Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110001 India.

Aim: To assess knowledge and attitude of women toward postpartum intrauterine contraceptive device (PPIUCD) and analyze reasons of refusal.

Setting And Design: Hospital-based cross-sectional study for 1 year.

Materials And Methods: 550 women were enrolled in the study. Read More

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June 2018
5 Reads

Women with bleeding disorders: Clinical and psychological issues.

Authors:
C McLintock

Haemophilia 2018 May;24 Suppl 6:22-28

Auckland City Hospital, National Women's Health, Auckland, New Zealand.

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Cotyledonoid Dissecting Leiomyoma of the Uterus: An Unexpected Diagnosis After Delivery.

Acta Med Port 2018 Apr 30;31(4):223-227. Epub 2018 Apr 30.

Serviço de Ginecologia-Obstetrícia. Departamento da Mulher e da Criança. Hospital de Santarém. Santarém, Portugal.

Cotyledonoid dissecting leiomyoma, also known as Sternberg tumor, is a rare benign uterine tumor with a gross and radiological appearance that may suggest the possibility of a malignancy. We report a case of a thirty-eight-year-old female patient who presented with menorrhagia and abdominal pain one month after delivery by cesarean section. An ultrasound scan showed a heterogeneous pelvic mass, near the isthmic region, with 25 x 24 x 23 mm without vascularization so the possibility of placenta accreta could not be excluded. Read More

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April 2018
4 Reads

Epidemiology of uterine myomas and clinical practice in Spain: An observational study.

Eur J Obstet Gynecol Reprod Biol 2018 Jul 21;226:59-65. Epub 2018 May 21.

Hospital de la Santa Creu i Sant Pau, Universitat Autónoma, Barcelona, Spain.

Objective: Characterization of the clinical features of symptomatic uterine myomas in Spanish women visiting the gynaecologist, including impact on quality of life and possible risk factors, description of main therapeutic approaches, and evaluation of symptom and quality of life progression 6 months after inclusion in the study.

Study Design: This was an observational, epidemiological, non-interventional, multicentre study performed between June 2015 and March 2016. Data were collected at baseline and follow-up visits 6 months apart from women with a diagnosis of uterine myomas and visiting a participating gynaecologist in outpatient units of private clinics or public hospitals in Spain. Read More

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July 2018
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Outcome of Total Laparoscopic Hysterectomy.

J Coll Physicians Surg Pak 2018 Jun;28(6):427-430

Department of Obstetrics and Gynecologic Endoscopic Unit, Patel Hospital, Karachi.

Objective: To determine the surgical outcomes of total laparoscopic hysterectomy performed.

Study Design: Case series.

Place And Duration Of Study: Obstetrics and Gynecologic Endoscopic Unit of Patel Hospital, Karachi, from February 2013 till February 2016. Read More

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Hemorrhagic disorders of fibrinolysis: a clinical review.

J Thromb Haemost 2018 May 30. Epub 2018 May 30.

Department of Hematology, Catharina Hospital, Eindhoven, the Netherlands.

Hyperfibrinolytic bleeding can be caused by a deficiency of one of the inhibitors of fibrinolysis (plasminogen activator inhibitor type 1 [PAI-1] or α2-antiplasmin [α2-AP]), or an excess of one of the activators of fibrinolysis: tissue-type plasminogen activator or urokinase-type plasminogen activator. This review focuses on the clinical implications of these disorders. The bleeding phenotype of fibrinolytic disorders is characterized by delayed bleeding after trauma, surgery and dental procedures. Read More

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May 2018
7 Reads

Conservative surgery of uterine adenomyosis via laparoscopic versus laparotomic approach in a single institution.

J Obstet Gynaecol Res 2018 Jul 29;44(7):1268-1273. Epub 2018 May 29.

Department of Obstetrics and Gynaecology, Ulsan University Hospital, University of Ulsan College of Medicine, Dong-gu Ulsan, South Korea.

Aims: To evaluate the surgical outcomes of both approach methods (laparoscopy vs laparotomy) and to suggest the proper surgical approach according to type of uterine adenomyosis (focal vs diffuse).

Methods: We retrospectively analyzed 224 cases of uterine adenomyomectomy, 116 laparotomic and 108 laparoscopic, performed between July 2011 and June 2016 by a single surgeon (Y. S. Read More

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July 2018
3 Reads