Search Our Scientific Publications & Authors

Redox Biol 2019 Apr 15;24:101204. Epub 2019 Apr 15.

Department of Physiology and Pharmacology, Sackler Medical School, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Recently, Weber et al. published a thorough investigation of the age-dependency of oxidative stress (OS) determined by the steady state concentrations of different compounds - oxidation products and antioxidants - that are in common use as biomarkers of OS in 2207 healthy individuals of the cross-sectional MARK-AGE Project. The correlations among biomarkers were significant but weak. Read More

Neurosci Res 2019 Apr 22. Epub 2019 Apr 22.

Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Japan. Electronic address:

Depression and anxiety, which are severe symptoms during menopause, are caused by ceased ovarian activity and declined serum progesterone levels. Studies have demonstrated that gut microbiota can regulate brain function and change the microbiota composition during the perimenopause period. This study investigated whether progesterone affects depressant and anxious behaviors via gut microbiota. Read More

Menopause 2019 May;26(5):554-556

Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky.

Asymptomatic ovarian tumors in menopausal women do not always require surgical removal. Experts recommend an initial evaluation with transvaginal ultrasound to help characterize the tumor's malignant risk. Low-risk tumors can be monitored with ultrasound, whereas high-risk tumors should be referred to a gynecologic oncologist. Read More

Menopause 2019 Apr 22. Epub 2019 Apr 22.

Department of Gynecology, People's Hospital of Rongchang District, Chongqing, China.

Objective: The aim of this study was to assess the comparative effectiveness and safety of different pharmacological agents, including abaloparatide and romosozumab, for treatment of osteoporosis in postmenopausal women.

Methods: We searched PubMed, Embase, the Cochrane Central Register of Controlled Trials, and Google Scholar for relevant randomized controlled trials published up to July 16, 2018. After study selection according to the preplanned criteria, we performed data extraction and quality assessment. Read More

Climacteric 2019 Apr 24. Epub 2019 Apr 24.

b Department of Gynecology , Wesley Hospital , Brisbane , Australia.

J Diabetes Investig 2019 Apr 23. Epub 2019 Apr 23.

Department of Endocrine and Metabolic Diseases, the First Affiliated Hospital of Wenzhou Medical University, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.

Aims: Exercise training is a recognized strategy central to the prevention, treatment and management of diabetes and prediabetes. The present study was to investigate the association between physical activity and blood glucose, as well as the influence of sex, menopause status, and family history of diabetes.

Materials And Methods: Participants with normal weight were selected from REACTION study, and divided into inactive (moderate-to-vigorous-intensity physical activity [MVPA] < 30 min/week), low-degree (MVPA ≥ 30 and ≤ 420 min/week), and high-degree (MVPA > 420 min/week) active groups. Read More

Climacteric 2019 Apr 23:1-6. Epub 2019 Apr 23.

a Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology , The University of the State of Rio de Janeiro , Rio de Janeiro , Brazil.

Background: Menopause and deficiency in vitamin D (VD) are two health problems usually associated with aging women.

Objective: We aimed to study inflammation in visceral adipose tissue when bilateral ovariectomy is combined with dietary restriction in VD.

Methods: We studied 60 female C57BL/6 mice 3 months of age. Read More

Climacteric 2019 Apr 23:1-9. Epub 2019 Apr 23.

a School of Pharmacy , University of Queensland , Woolloongabba , QLD , Australia.

Purpose: This study aimed to examine the longitudinal impact of evidence changes on menopausal hormone therapy (MHT) use in Australia.

Methods: We analyzed two datasets of subsidized and total MHT use (2000-2016) using segmented regression analysis to explore the impact of the Women's Health Initiative (WHI) 2002 and 2007 studies. Analyses were stratified by class, route, and strength. Read More

Nutrients 2019 Apr 19;11(4). Epub 2019 Apr 19.

Department of Food and Nutrition, Wonkwang University, 460 Iksandaero, Iksan, Jeonbuk 54538, Korea.

Post menopause is considered a critical period for bone-mass loss. Impaired bone metabolism during this phase can increase the risk of fractures in old age. Inflammation is a risk factor for bone health, and diet is a potential source of inflammation. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Apr 15;237:48-56. Epub 2019 Apr 15.

Department of Woman, Newborn and Child, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Clinical Sciences and Community Health, Università degli studi di Milano, Milan, Italy. Electronic address:

Background: Endometrial polyps are a common condition. The risk of malignancy has often led to an overtreatment with high health care costs and huge psychological distress.

Objective: We conducted a systematic review and a meta-analysis in order to estimate the prevalence of premalignant and malignant lesions in women undergoing hysteroscopic polypectomy. Read More

J Ethnopharmacol 2019 Apr 19:111885. Epub 2019 Apr 19.

Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing, 210023, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address:

Ethnopharmacological Relevance: Kuntai capsule (KTC), a type of herb formulas, was first described in the book of Shang Han Za Bing Lun in the third century. KTC has been widely used for the clinical treatment of menopausal syndrome. Considering that premature ovarian failure is also known as premature menopause, this study was designed to investigate the effects and mechanisms of KTC on a mouse model of premature ovarian failure. Read More

Eur J Cancer Care (Engl) 2019 Apr 22:e13040. Epub 2019 Apr 22.

Joven & Fuerte: Program for the Care and Research of Young Women with Breast Cancer in Mexico, Mexico City, Mexico.

Objective: To describe clinical and information needs, identify unmet support services and guide interventions for young breast cancer (BC) patients in Mexico.

Methods: Cross-sectional, qualitative study, using interpretive description methodology. Patients with initial BC diagnosis within 6-12 months prior to enrolment, ≤40 years old and literate were included in focus groups. Read More

J Clin Endocrinol Metab 2019 Apr 22. Epub 2019 Apr 22.

Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht, Utrecht, The Netherlands.

Context: Anti-Müllerian hormone (AMH) levels are currently used worldwide as a screening tool for the duration of the female reproductive lifespan. Although AMH levels are associated with age at menopause, individual predictions of menopause with a single AMH measurement are unreliable.

Objective: This study investigated whether individual AMH decline patterns can improve the prediction of menopause compared to a single measurement. Read More

Gynecol Endocrinol 2019 Apr 22:1-5. Epub 2019 Apr 22.

d Gynecological Endocrinology Unit, Division of Endocrinology , Hospital de Clínicas de Porto Alegre , Porto Alegre , Brazil.

The aim of this study was to investigate the association between individual risk factors and coronary artery calcification (CAC), as a marker of subclinical cardiovascular disease, in a population-based nested cross-sectional study of midlife women. Anthropometric and metabolic data from 295 women from the South of Brazil were analyzed. Habitual physical activity was assessed by pedometer. Read More

Mol Biol Rep 2019 Apr 20. Epub 2019 Apr 20.

School of Life and Environmental Sciences, University of Sydney, Sydney, Australia.

Ovarian cancer (OC) is the fourth most common cancer among Pakistani, Scottish and Chinese women. The aim of the present study was to determine the association of potential risk factors with OC and analysis of Cancer Antigen 125 (CA125) in its monitoring and diagnosis. A total of 200 patients diagnosed with OC were included in this study. Read More

Semin Reprod Med 2018 Nov 19;36(6):315-322. Epub 2019 Apr 19.

Division of Gynecology, Department of Surgery, VA Boston Healthcare System, Boston, Massachusetts.

The literature on the reproductive health and healthcare of women Veterans has increased dramatically, though there are important gaps. This article aims to synthesize recent literature on reproductive health and healthcare of women Veterans. We updated a literature search to identify manuscripts published between 2008 and July 1, 2017. Read More

Clin Chim Acta 2019 Apr 16;494:151-156. Epub 2019 Apr 16.

School of Allied Health Sciences, Walailak University, 222 Thaiburi, Thasala, Nakhon Si Thammarat, Thailand. Electronic address:

Background: High PCSK9 concentrations are associated with an increased risk of cardiovascular disease (CVD). We investigated PCSK9 concentrations and their association with metabolic parameters in Thai subjects and to compare PCSK9 concentrations in pre- and postmenopausal women with and without metabolic syndrome (MetS).

Methods: Anthropometric data, serum lipids, fasting blood glucose (FBG), and PCSK9 concentrations were measured in 436 Thai subjects (152 men, 143 premenopausal, and 141 postmenopausal women). Read More

Horm Cancer 2019 Apr 18. Epub 2019 Apr 18.

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Natural course of prolactinomas after menopause is not fully elucidated. The aim of this study was to compare recurrence rate after cabergoline withdrawal in premenopausal vs. postmenopausal women with microprolactinoma. Read More

J Midlife Health 2019 Jan-Mar;10(1):33-36

Department of Obstetrics and Gynaecology, Maulana Azad Medical College, Delhi, India.

Background: Menopause is defined as the time of cessation of ovarian function resulting in permanent amenorrhea. Menopause is associated with various symptoms such as physical, vasomotor, sexual, and psychological symptoms. Depression is a common symptom in postmenopausal women as menopause is associated with the end of the fertile period of a women's life. Read More

J Midlife Health 2019 Jan-Mar;10(1):14-21

OBGY, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.

Context: Menopause is a crucial phase of the women fraternity which marks the end of reproductive age. Mostly it is physiological; however, certain conditions may lead to premature menopause. Menopause has an extensive spectrum of symptoms which are extremely bothersome. Read More

J Midlife Health 2019 Jan-Mar;10(1):6-13

Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Hot flashes (HFs), defined as transient sensations of heat, sweating, flushing, anxiety, and chills lasting for 1-5 min, constitute one of the most common symptoms of menopause among women though only a few seek treatment for these. The basis of HFs lies in abnormal hypothalamic thermoregulatory control resulting in abnormal vasodilatory response to minor elevations of core body temperature. Recent data suggest an important role for calcitonin gene-related peptide, hypothalamic kisspeptin, neurokinin B and dynorphin signal system, serotonin, norepinephrine in causation of HFs in addition to estrogen deficiency which plays a cardinal role. Read More

J Midlife Health 2019 Jan-Mar;10(1):1-2

Professor, Department of Obs Gynae, PGIMER, Chandigarh, Punjab, India. E-mail:

Reprod Biomed Online 2019 Feb 28. Epub 2019 Feb 28.

Centre for Reproductive Medicine, Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, China. Electronic address:

Research Question: The family with sequence similarity 175 member A gene (FAM175A; also known as ABRAXAS1, CCDC98 and ABRA1), a member of the DNA repair family, contributes to the BRCA1 (BRCA1 DNA repair associated)-dependent DNA damage response and is associated with age at natural menopause. However, it remains poorly understood whether sequence variants in FAM175A are causative for premature ovarian insufficiency (POI). The aim of this study was to investigate whether mutations in the gene FAM175A were present in patients with POI. Read More

Int J Womens Dermatol 2019 Jun 15;5(2):85-90. Epub 2019 Mar 15.

Montefiore Medical Center, Department of Medicine, Division of Dermatology, Bronx, New York.

Menopause is a major turning point in a woman's life that is characterized by declining ovarian function and decreased serum estrogen levels. The resulting hormonal changes particularly affect the skin, with postmenopausal symptoms such as loss of structural architecture and increased propensity to damage becoming rapidly noticeable. Interestingly, studies have shown that estrogen deprivation in postmenopausal conditions accelerates many skin changes, including dryness, atrophy, fine wrinkling, and poor wound healing. Read More

Rev Med Suisse 2019 Apr;15(647):836-839

Centre des maladies osseuses, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.

Changes occurring at menopause can be mitigated by prescribing menopausal hormone replacement therapy (HRT). Recent publications from the CoLaus/OsteoLaus cohorts provide important insights into the effects of HRT and after its discontinuation on bone and body composition. HRT has a beneficial effect on bone mineral density, bone microarchitecture and fracture prevention. Read More

Rev Assoc Med Bras (1992) 2019 Mar;65(3):292-294

Department of Endocrine Gynecology and Menopause, Discipline of Gynecology and Obstetrics, Hospital das Clínicas, Faculty of Medicine of the University of São Paulo; São Paulo, Brasil.

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Department of Endocrinology, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.

Objective: Osteoporosis has become an important public health problem in China, especially among elderly postmenopausal women. Massive amounts of medical and health resources have been devoted to patients with osteoporosis and osteoporosis-related fractures. This study estimated the cost-effectiveness of alendronate, zoledronate, raloxifene, teriparatide, and calcium/vitamin D as treatments for osteoporosis in elderly postmenopausal women in China from the medical system perspective. Read More

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.

Objective: To evaluate the efficacy of two common interventions for bothersome postmenopausal vaginal symptoms on improving sexual frequency and pain.

Methods: This is a post-hoc analysis of data from a 12-week double-blind placebo-controlled trial that randomized postmenopausal women (ages 45-70 years) with moderate-severe genitourinary discomfort to vaginal 10 μg estradiol tablet plus placebo gel (n = 102), placebo tablet plus vaginal moisturizer (n = 100), or dual placebo (n = 100). Outcomes were proportion of sexually active women at 12 weeks, frequency of sexual activity, and pain severity with sexual activity (0-3 scale). Read More

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Women's Health Research Program, Monash University, Melbourne, Victoria, Australia.

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC.

Objective: Past studies indicate that >90% of breast cancer survivors taking adjuvant endocrine therapy (AET) experience menopausal symptoms including sexual problems (eg, vaginal dryness, dyspareunia); however, research examining the impact of these problems on quality-of-life is limited. This cross-sectional study examined (1) the impact of sexual problems and self-efficacy for coping with sexual problems (sexual self-efficacy) on quality-of-life (ie, psychosocial quality-of-life and sexual satisfaction), and (2) partner status as a moderator of these relationships.

Methods: Postmenopausal breast cancer survivors taking AET completed measures of sexual problems (Menopause-Specific Quality-of-Life [MENQOL] sexual subscale], sexual self-efficacy, psychosocial quality-of-life (MENQOL psychosocial subscale), and sexual satisfaction (Functional Assessment of Cancer Therapy-General item). Read More

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Department of Female Pelvic Medicine and Reconstructive Surgery, The Christ Hospital, Cincinnati, OH.

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Hospital Universitario San Jorge, Periera, Colombia Department of Gynecology, Ospedale San Raffaele, Milan, Italy Urogynecology Unit, Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Athens, Greece Department of Obstetrics and Gynecology, Diatros Barcelona, Barcelona, Spain Cosmetic Gynecology and General Surgery, Universidad de Buenos Aires Secretaria de Ciencia y Tecnica, Buenos Aires, Argentina Clinica de Gineco Endocrino, Complejo Hospitalario Metropolitano Caja Seguro Social Panama, Panama Nidad de Ginecoestitica Laser Madrid Spain, Madrid, Spain Department of Surgical and Morphological Studies, Universita degli Studi dell'Insubria, Varese, Italy Academia Nacional de Medicina Colombia, Bogota, Colombia.

Menopause 2019 Apr 15. Epub 2019 Apr 15.

Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL.

Objective: The aim of the study was to review the management of endometrial hyperplasia in a woman undergoing liver transplantation for alcoholic cirrhosis.

Methods: This is a case presentation on a postmenopausal woman with a tissue diagnosis of endometrial intraepithelial neoplasia managed with a levonorgestrel intrauterine device, before and after liver transplantation. Full written informed consent was obtained from the patient to present her case. Read More

Menopause 2019 Apr 15. Epub 2019 Apr 15.

School of Nursing, Indiana University, Indianapolis, IN.

Objective: Women's sleep at menopause is widely reported to be problematic. The Insomnia Severity Index (ISI) is a commonly used tool for quantifying sleep problems in clinical and research settings, but psychometric properties in postmenopausal women have not been reported. Our study aim was to examine the factor structure of the ISI in a large and diverse sample of midlife women with hot flashes. Read More

J Cardiovasc Imaging 2019 Apr;27(2):147-149

Division of Cardiology, Department of Internal Medicine, Hanyang University Medical Center, College of Medicine, Hanyang University, Seoul, Korea.

J Cardiovasc Imaging 2019 Apr;27(2):137-146

Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.

Background: This study evaluated the atrial electromechanical delay (AEMD) and the left atrial (LA) mechanical functions in patients with surgical early menopause.

Methods: A total of 62 patients were included in the study: 33 patients with surgical early menopause and 29 age- and sex-matched healthy controls. The duration distance from the start of the P wave to the beginning of the A wave for the lateral mitral annulus, septal mitral annulus, and lateral tricuspid annulus was assessed by tissue Doppler echocardiography. Read More

Endocrine 2019 Apr 16. Epub 2019 Apr 16.

Department of Medicine, University of Padova, Padova, Italy.

Purpose: Hormonal status and menopause affect human macrophage function and cardiometabolic risk. In polycystic ovary syndrome (PCOS) patients the cardiometabolic risk increases through mechanisms that are largely unknown. We tested the hypotheses that macrophage activation is influenced by menstrual cycle and that ovarian dysfunction in PCOS patients is associated with altered macrophage inflammatory responses and cholesterol efflux capacity of serum HDL. Read More

J Cancer Prev 2019 Mar 30;24(1):26-32. Epub 2019 Mar 30.

Department of Medicine, Hanyang University College of Medicine, Seoul, Korea.

Background: This study was conducted to explore the effect of known risk factors, focusing on risk factors including age at menarche, age at menopause, number of children, family history of breast cancer, and age at first birth according to breast density, in consideration of interaction among East-Asian women.

Methods: Case-control study with 2,123 cases and 2,121 controls with mammographic density was conducted. Using the mammographic film, breast density was measured using Breast Imaging-Reporting and Data System. Read More

J Neurosci 2019 Apr 16. Epub 2019 Apr 16.

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 916 Hunterian Building, 725 N. Wolfe Street, Baltimore, MD, 21205, USA

Surgical ovariectomy has been shown to reduce spine density in hippocampal CA1 pyramidal cells of rodents, and this reduction is reversed by 17β-estradiol (E2) treatment in a model of human estrogen replacement therapy. Here, we report reduction of spine density in apical dendrites of layer 5 pyramidal neurons of several neocortical regions that is reversed by subsequent E2 treatment in ovariectomized (OVX) female Thy1M-EGFP mice. We also found that OVX-associated reduction of spine density in somatosensory cortex was accompanied by a reduction in mEPSC frequency (but not mIPSC frequency), indicating a change in functional synapses. Read More

Eur J Sport Sci 2019 Apr 16:1-9. Epub 2019 Apr 16.

a Department of Health Sciences, Faculty of Health Sciences , University of Jaén , Jaén , Spain.

Objective: the main objective was to analyze the effects that an exercise programme based on the Pilates method would have on balance confidence, fear of falling, and postural control among women ≥60 years old.

Methods: a total of 110 women (69.15 ± 8. Read More

J Clin Med 2019 Apr 4;8(4). Epub 2019 Apr 4.

Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

This study was performed to assess the relationship between menstrual irregularity and dental pain or chewing discomfort in women before menopause, using nationally representative data. This study analyzed 4595 participants who were ≥19 years or older, and did not have missing values for outcome variables from the Korean National Health and Nutrition Examination Survey. Tooth pain was considered present if the participant felt throbbing discomfort, pain, or sensitivity when eating hot or cold food or drinking hot or cold beverages. Read More

Med Sci Sports Exerc 2019 May;51(5):874-881

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

In this review, we highlight the underlying mechanisms responsible for the sex differences in the exercise pressor reflex (EPR), and, importantly, the impact of sex hormones and menopausal status. The EPR is attenuated in premenopausal women compared with age-matched men. Specifically, activation of the metaboreflex (a component of the EPR) results in attenuated increases in blood pressure and sympathetic vasomotor outflow compared with age-matched men. Read More

Indian Dermatol Online J 2019 Mar-Apr;10(2):97-105

Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Polycystic ovarian syndrome (PCOS) is the commonest endocrine disorder in women having wide range of clinical manifestation. These women may present with reproductive, dermatological, metabolic, psychological, or neoplastic implications from adolescence to menopause. The common dermatological manifestations include hirsutism, acne, alopecia, or acanthosis nigricans. Read More

EPMA J 2019 Mar 2;10(1):73-79. Epub 2019 Mar 2.

9Radiological clinic, UKB, Rheinische Friedrich-Wilhelms-University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.

Vaginal dryness (VD) affects both pre- and postmenopausal women at any age. Since the hormonal regulation changes during the climacteric period are considered as being the main course of the VD, affected women prefer not to talk about the problem. However, the problem does exist, and unfortunately if any, relatively minor group in the population possesses the health literacy at sufficient level to understand that VD is a suboptimal health condition which carries a multi-factorial character. Read More

Front Aging Neurosci 2019 28;11:70. Epub 2019 Mar 28.

Genetics and Aging Research Unit, Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Harvard Medical School - Massachusetts General Hospital, Boston, MA, United States.

The argument is frequently made that the amyloid-β protein (Aβ) persists in the human genome because Alzheimer's disease (AD) primarily afflicts individuals over reproductive age and, therefore, there is low selective pressure for the peptide's elimination or modification. This argument is an important premise for AD amyloidosis models and therapeutic strategies that characterize Aβ as a functionless and intrinsically pathological protein. Here, we review if evolutionary theory and data on the genetics and biology of Aβ are consistent with low selective pressure for the peptide's expression in senescence. Read More

Indian J Dermatol 2019 Mar-Apr;64(2):136-142

Department of Dermatology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.

Background: In our hospital setup located in the tropical zone, during each summer, we frequently come across a unique eczematous dermatosis among elderly females that typically occur in summer.

Aims And Objectives: We carried out this study with the objective of studying the demographic and clinical features of this dermatosis.

Materials And Methods: In this hospital-based descriptive study, we enrolled twenty consecutive patients presenting with typical features of the dermatosis of interest, such as itchy eczematous scaly papule and plaques distributed predominantly over flexures, self-limiting in nature, and with summer exacerbation. Read More

Surg Obes Relat Dis 2019 Jan 11. Epub 2019 Jan 11.

National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.

Background: Lack of prospective trials have resulted in a dearth of information regarding postbariatric surgery conception rates in women with a preoperative history of infertility.

Objective: To examine associations between preoperative history of infertility and postbariatric surgery conception.

Setting: A multicenter cohort study at 10 United States hospitals (2006-2009). Read More

Wien Klin Wochenschr 2019 Apr 12. Epub 2019 Apr 12.

Interne Abteilung, Landeskrankenhaus Hochzirl - Natters, Hochzirl, Österreich.

Metabolic diseases dramatically affect the life of men and women from infancy up to old age in different and manifold ways and are a major challenge for the healthcare system. The treating physicians are confronted with the different needs of women and men in the clinical routine. Gender-specific differences affect screening, diagnostic and treatment strategies as well as the development of complications and mortality rates. Read More

Can Fam Physician 2019 Apr;65(4):260-263

Director of Programs and Practice Support for the College of Family Physicians of Canada and Professor in the Department of Family Medicine at the University of Alberta.

Objective: To summarize high-quality studies for 10 topics from 2018 that have strong relevance to primary care practice.

Quality Of Evidence: Study selection involved routine literature surveillance by a group of primary care health professionals. This included screening abstracts of important journals and Evidence Alerts, as well as searching . Read More

Osteoporos Int 2019 Apr 11. Epub 2019 Apr 11.

Department of Rheumatology, Changhai Hospital, Shanghai, China.

We performed a 1-year prospective study to see whether zoledronic acid infusion combined with percutaneous kyphoplasty could provide more benefits in the treatment of T12 or L1 osteoporotic vertebral compression fracture (OVCF).

Introduction: To investigate and analyze the clinical effects of zoledronic acid (ZOL) in combination with percutaneous kyphoplasty (PKP) in the treatment of OVCF in postmenopausal women.

Methods: Included in this study were 101 postmenopausal women patients with T12 or L1 OVCF who received PKP in our hospital between August 2015 and July 2017. Read More