12,818 results match your criteria Meniscus Injuries


Management of Long-Term Complications in the Setting of Lateral Meniscal Deficiency After Saucerization of a Discoid Lateral Meniscus in an Adolescent Patient: A Case Report and Review of the Literature.

JBJS Case Connect 2018 Dec 12. Epub 2018 Dec 12.

Elite Sports Medicine, Division of Orthopedic Surgery, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Farmington, Connecticut.

Case: A 14-year-old adolescent with bilateral discoid menisci who had previously undergone discoid meniscal saucerization presented with pain and mechanical knee symptoms bilaterally. She had a torn left discoid lateral meniscus, a right lateral meniscal deficiency with an associated osteochondral defect, and valgus collapse of the right femur. She underwent successful repair of the left discoid meniscus as well as a femoral osteotomy, a meniscal transplant, and an osteochondral allograft transplantation in the right knee. Read More

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December 2018

High short-term return to sports rate despite an ongoing healing process after acute meniscus repair in young athletes.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedic Sports Medicine, Klinikum Rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.

Purpose: Acute meniscus repair in young athletes is always a challenge due to the long rehabilitation process and time to return to sport (RTS). The purpose was to investigate signal alterations in short-term follow-up after acute meniscus repair on specific magnetic resonance imaging (MRI) scan sequences. It was hypothesized that (1) MRI signal changes over the first postoperative healing phase and represent a continuous healing process and (2) meniscus healing properties correlates with clinical outcomes and RTS. Read More

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December 2018

Evaluation of age-related differences in anterior cruciate ligament size.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

Purpose: The purpose of this study was to reveal the relation between age and the morphological characteristics of the anterior cruciate ligament (ACL) using magnetic resonance imaging (MRI).

Methods: Thirty-seven young subjects who were diagnosed with a meniscus injury without ACL tear using MRI (15 male and 22 female, median age 26, range 15-49), and 33 elderly subjects for whom knee MRI was performed before uni-compartmental knee arthroplasty (11 male and 22 female, median age 77, range 60-83), were included in this study. In the elderly group, healthy ACL gross morphology was confirmed macroscopically during surgery. Read More

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December 2018

Influence of Nanofiber Orientation on Morphological and Mechanical Properties of Electrospun Chitosan Mats.

J Healthc Eng 2018 13;2018:3651480. Epub 2018 Nov 13.

Department of Engineering for Innovation, University of Salento, Lecce 73100, Italy.

This work explored the use of chitosan (Cs) and poly(ethylene oxide) (PEO) blends for the fabrication of electrospun fiber-orientated meshes potentially suitable for engineering fiber-reinforced soft tissues such as tendons, ligaments, or meniscus. To mimic the fiber alignment present in native tissue, the CS/PEO blend solution was electrospun using a traditional static plate, a rotating drum collector, and a rotating disk collector to get, respectively, random, parallel, circumferential-oriented fibers. The effects of the different orientations (parallel or circumferential) and high-speed rotating collector influenced fiber morphology, leading to a reduction in nanofiber diameters and an improvement in mechanical properties. Read More

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November 2018

Clinical factors associated with contact lens dropout.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Centre for Ocular Research and Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada.

Purpose: Contact lens (CL) dropout is estimated to be approximately equal to the number of new wearers per year, resulting in virtually no growth in the global CL market. The purpose of this study was to determine ocular and CL factors associated with CL dropout.

Methods: This five-site study recruited subjects 18-45 years of age who had ceased CL wear within the past 6-12 months due to discomfort. Read More

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December 2018

Cellular and Chemical Gradients to Engineer the Meniscus-to-Bone Insertion.

Adv Healthc Mater 2018 Dec 10:e1800806. Epub 2018 Dec 10.

Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14850, USA.

Tissue-engineered menisci hold promise as an alternative to allograft procedures but require a means of robust fixation to the native bone. The insertion of the meniscus into bone is critical for meniscal function and inclusion of a soft tissue-to-bone interface in a tissue engineered implant can aid in the fixation process. The native insertion is characterized by gradients in composition, tissue architecture, and cellular phenotype, which are all difficult to replicate. Read More

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December 2018
1 Read

Save the meniscus again!

Knee Surg Sports Traumatol Arthrosc 2018 Dec 10. Epub 2018 Dec 10.

Orthopaedic Department, Centre Hospitalier de Versailles, 177, rue de Versailles, 78157, Le Chesnay, France.

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December 2018

Technique for Arthroscopically Assisted Superficial and Deep Medial Collateral Ligament-Meniscotibial Ligament Repair With Internal Brace Augmentation.

Arthrosc Tech 2018 Nov 29;7(11):e1215-e1219. Epub 2018 Oct 29.

Taos Orthopaedic Institute, Taos, New Mexico, U.S.A.

Deep medial collateral ligament (MCL) injury leads to meniscal lift-off and extrusion of the medial meniscus, resulting in instability and increased medial compartment pressures with subsequent cartilage damage. Repair of the deep MCL meniscotibial ligament in concert with superficial MCL repair or reconstruction is intended to restore the native anatomy , stability, and function of the medial meniscus. We present an arthroscopically assisted technique using standard arthroscopy portals and a medial open approach. Read More

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November 2018
1 Read

Outside-In Single-Lasso Loop Technique for Meniscal Repair: Fast, Economic, and Reproducible.

Arthrosc Tech 2018 Nov 22;7(11):e1191-e1196. Epub 2018 Oct 22.

Hospital Universitario de Torrejón, Torrejón de Ardoz, Spain.

The current understanding of the biomechanical role of the meniscus, in conjunction with the increasing efforts to achieve its preservation within the orthopaedic community during treatment of meniscal lesions, has prompted the development of different meniscal repair techniques. The outside-in technique is recommended for anterior horn and middle-segment meniscal tears and has been recognized as a low-cost procedure with a low incidence of complications. Diverse modifications of this technique have been published over the past decade. Read More

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November 2018

All-epiphyseal Anterior Cruciate Ligament Reconstruction Does Not Increase the Risk of Complications Compared With Pediatric Transphyseal Reconstruction.

J Am Acad Orthop Surg 2018 Dec 10. Epub 2018 Dec 10.

From the The Children's Hospital of Philadelphia, Philadelphia, PA.

Introduction: Complication rates after physeal-sparing anterior cruciate ligament reconstruction (ACLR) are known to be high in the paediatric population compared with the adult population. However, the outcomes of these skeletally immature patients after all-epiphyseal reconstruction have not been compared with those after transphyseal reconstructions in a more similar age group. This study compares clinical outcomes and complications between all-epiphyseal and pediatric transphyseal ACLR. Read More

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December 2018

How Do Race and Insurance Status Affect the Care of Pediatric Anterior Cruciate Ligament Injuries?

Clin J Sport Med 2018 Nov 28. Epub 2018 Nov 28.

Division of Orthopaedics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Objective: To identify associations between race or insurance status and preoperative, intraoperative, and postoperative findings in a large cohort of pediatric anterior cruciate ligament (ACL) reconstructions.

Design: Retrospective cohort study.

Setting: Division of Orthopaedics at an urban tertiary care children's hospital. Read More

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November 2018

A 3D printed PCL/hydrogel construct with zone-specific biochemical composition mimicking that of the meniscus.

Biofabrication 2018 Dec 7. Epub 2018 Dec 7.

Biological Sciences, METU, Ankara, TURKEY.

Engineering the meniscus is challenging due to its bizonal structure; the tissue is cartilaginous at the inner portion and fibrous at the outer portion. Here, we constructed an artificial meniscus mimicking the biochemical organization of the native tissue by 3D printing a meniscus shaped PCL scaffold and then impregnating it with agarose (Ag) and gelatin methacrylate (GelMA) hydrogels in the inner and outer regions, respectively. After seeding the constructs with porcine fibrochondrocytes and incubating for 8 weeks, we demonstrated that presence of Ag enhanced glycosaminoglycan (GAG) production by about 4 fold (p<0. Read More

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December 2018

Penetration dynamics through nanometer-scale hydrophilic capillaries: Beyond Washburn's equation and extended menisci.

J Colloid Interface Sci 2018 Dec 3;538:340-348. Epub 2018 Dec 3.

Department of Chemical Engineering, National Taiwan University, Taipei 106, Taiwan. Electronic address:

Hypothesis: Recently, the naoncapillary devices with the channel width about 2-3 water molecules have been fabricated. Water transport through these nanoslits showed unexpectedly fast flow, revealing the failure of Washburn's equation.

Experiments: Liquid penetration into a nanocapillary made of two parallel walls is explored by many-body dissipative particle dynamics. Read More

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December 2018

Dynamical modeling of manipulation process in Trolling-Mode AFM.

Ultramicroscopy 2018 Dec 5;197:83-94. Epub 2018 Dec 5.

Tarbiat Modares University, Jalal Al. Ahamd, Tehran 00000, Iran.

Dynamical lumped modeling of Trolling-mode AFM in manipulation of bio-samples is presented. The combination of high accuracy and compatibility with physiological conditions makes AFM a unique tool for studying biological materials in liquid medium. However, AFM microcantilever suffers from severe sensitivity degradation and noise intensification while operating in liquid; the large hydrodynamic drag between the cantilever and the surrounding liquid overwhelms the tip-sample interaction forces that are important in controlling the process. Read More

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December 2018

An efficient and fast computer-aided method for fully automated diagnosis of meniscal tears from magnetic resonance images.

Artif Intell Med 2018 Dec 4. Epub 2018 Dec 4.

Computer Engineering Department, Yıldız Technical University, İstanbul, Turkey. Electronic address:

Menisci are structures that directly affect movement, so early detection of meniscus tears also helps to prevent progressive knee disorders such as osteoarthritis. Manual segmentation of the menisci and diagnosis of the meniscal tear is a costly process in terms of time and effort for a radiologist. The aim of this study is to automatically determine the location and the type of meniscal tears that are important in the diagnosis and effective treatment of this problem. Read More

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December 2018

Quantitative and Qualitative Assessment of the Posterior Medial Meniscus Anatomy: Defining Meniscal Ramp Lesions.

Am J Sports Med 2018 Dec 7:363546518814258. Epub 2018 Dec 7.

The Steadman Clinic, Vail, Colorado, USA.

Background:: Meniscal ramp lesions have been defined as a tear of the peripheral attachment of the posterior horn of the medial meniscus (PHMM) at the meniscocapsular junction or an injury to the meniscotibial attachment. Precise anatomic descriptions of these structures are limited in the current literature.

Purpose:: To quantitatively and qualitatively describe the PHMM and posteromedial capsule anatomy pertaining to the location of a meniscal ramp lesion with reference to surgically relevant landmarks. Read More

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December 2018

Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes.

Oman J Ophthalmol 2018 Sep-Dec;11(3):207-212

Department of Ophthalmology, Mahatma Gandhi Mission's Medical College and Hospital, Navi Mumbai, Maharashtra, India.

Aim: The aim of this study is to evaluate the efficacy of 2% rebamipide ophthalmic solution on the tear functions and ocular surface status in patients with dry eyes.

Materials And Methods: A prospective study was carried out on forty eyes of patients having signs and symptoms of dry eye. Two percent rebamipide ophthalmic solution was applied four times a day for a period of 4 weeks. Read More

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December 2018
4 Reads

Considerations for translation of tissue engineered fibrocartilage from bench to bedside.

J Biomech Eng 2018 Dec 5. Epub 2018 Dec 5.

ASME Fellow, Distinguished Professor, Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697.

Fibrocartilage is found in the knee meniscus, the temporomandibular joint (TMJ) disc, the pubic symphysis, the annulus fibrosus of intervertebral disc, tendons, and ligaments. These tissues are notoriously difficult to repair due to their avascularity, and limited clinical repair and replacement options exist. Tissue engineering has been proposed as a route to repair and replace fibrocartilages. Read More

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December 2018

Increased susceptibility to develop spontaneous and post-traumatic osteoarthritis in Dot1l-deficient mice.

Osteoarthritis Cartilage 2018 Dec 1. Epub 2018 Dec 1.

Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium. Electronic address:

Objective: We earlier identified that the histone methyltransferase DOT1L is as a master protector of cartilage health via limiting excessive activation of the Wnt pathway. However, cartilage-specific homozygous Dot1l knockout mice exhibited a severe growth phenotype and perinatal death, which hampered their use in induced or ageing models of osteoarthritis (OA). The aim of this study was to generate and examine haploinsufficient and inducible conditional Dot1l-deficient mouse models to evaluate the importance of DOT1L during post-traumatic or ageing-associated OA onset and progression. Read More

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December 2018
2 Reads

Comment on: 'Anterior cruciate ligament reconstruction performed within 12 months of the index injury is associated with a lower rate of medial meniscus tears' by Mok et al.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 3. Epub 2018 Dec 3.

Department of General Practice, Erasmus MC University Medical Center Rotterdam, Postbus 2040, 3000 CA, Rotterdam, The Netherlands.

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December 2018
1 Read

Torn discoid lateral meniscus is associated with increased medial meniscal extrusion and worse articular cartilage status in older patients.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 3. Epub 2018 Dec 3.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, No.37, Guoxue Alley, Chengdu, 610041, China.

Purpose: To compare the clinical, imaging, and arthroscopic characteristics of the torn discoid lateral meniscus (TDLM) in patients greater than 40 years of age with matched controls.

Methods: One hundred and ninety-four older patients (211 knees) who underwent arthroscopic surgery for a TDLM were consecutively recruited (Group 1). Another 211 age- and sex-matched controls with a torn semilunar lateral meniscus were included in this study (Group 2). Read More

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December 2018

Cross-linked hyaluronic acid gel occlusive device for the treatment of dry eye syndrome.

Authors:
John P Fezza

Clin Ophthalmol 2018 8;12:2277-2283. Epub 2018 Nov 8.

Center for Sight, Sarasota, FL, USA,

Purpose: A new cross-linked hyaluronic acid (xlHA) gel occlusive device was assessed for safety and efficacy in the treatment of dry eyes.

Methods: This was an institutional review board-approved, single-site, open-label, prospective study to assess the efficacy and safety of placing the xlHA gel in the lower canaliculus. Seventy-four participants aged 25-95 years with dry eyes, who failed treatment with artificial tears, were included. Read More

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November 2018
3 Reads

Comparison of T2* mapping between regular echo time and ultrashort echo time with 3D cones at 3 tesla for knee meniscus.

Medicine (Baltimore) 2018 Nov;97(48):e13443

Department of Radiology, Research Institute of Radiological Science, YUHS-KRIBB, Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul.

The objectives of this study were to compare the ultrashort T2* relaxation time with the T2* relaxation time using the 3 dimensional (3D) cones sequence in 3 groups of patients with normal, degenerated, and torn knee menisci, and to demonstrate the additional effect of the ultrashort echo time (UTE) signal intensity.Following institutional review board approval, 42 knee magnetic resonance imaging (MRI) scans of 42 patients who presented with knee pain and underwent knee MRIs, with the 3D Cones of UTE sequence (minimum TEs: 32 μs) and a 3T MRI scanner (Discovery 750, GE Healthcare, Waukesha, WI), were analyzed. The enrolled patients were classified into 3 subgroups:normal meniscus on conventional MRI, with no positive meniscus-related physical examination in medical records;meniscal degeneration with signal changes on conventional MRI; andmeniscal tear. Read More

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November 2018

Description of a surgical technique of medial meniscus root repair: a fixation technique with two simple stiches under an expected initial tension.

Eur J Orthop Surg Traumatol 2018 Nov 29. Epub 2018 Nov 29.

Department of Orthopaedic Surgery, Okayama University Hospital, 2-5-1 Shikatacho, Kitaku, Okayama, 700-8558, Japan.

The medial meniscus (MM) posterior root has an important role in the maintenance of knee kinematics and articular cartilage. Although transtibial pullout repair of the MM posterior root tear (MMPRT) has become the gold standard, it is associated with several suturing difficulties. The present technical note describes a simple fixation technique using two simple stiches under an expected initial tension. Read More

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November 2018
2 Reads

Differential protein expression in human knee articular cartilage and medial meniscus using two different proteomic methods: a pilot analysis.

BMC Musculoskelet Disord 2018 Nov 29;19(1):416. Epub 2018 Nov 29.

Department of Clinical Sciences Lund, Rheumatology and Molecular Skeletal Biology, Lund University, Faculty of Medicine, Lund, Sweden.

Background: Proteomics is an emerging field in the study of joint disease. Our two aims with this pilot analysis were to compare healthy human knee articular cartilage with meniscus, two tissues both known to become affected in the osteoarthritic disease process, and to compare two mass spectrometry (MS)-based methods: data-dependent acquisition (DDA) and data-independent acquisition (DIA).

Methods: Healthy knee articular cartilage taken from the medial tibial condyle and medial meniscus samples taken from the body region were obtained from three adult forensic medicine cases. Read More

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November 2018
2 Reads

A Systematic Review and Meta-Analysis of Arthroscopic Meniscus Repair in Young Patients: Comparison of All-Inside and Inside-Out Suture Techniques.

Knee Surg Relat Res 2018 Nov 29. Epub 2018 Nov 29.

Department of Orthopaedic Surgery, The Armed Forces Daegu Hospital, Gyeongsan, Korea.

Purpose: The purposes of the present study were to review published studies that investigated arthroscopic meniscus repair to treat meniscus injury in young patients and to compare all-inside and inside-out suture techniques.

Methods: Various electronic databases were queried for published articles, and this search was updated in August 2017 for evaluating the outcomes of arthroscopic meniscus surgery in young patients. Data search, extraction, analysis, and quality assessment were performed according to the Cochrane Collaboration guidelines, and the clinical outcomes were evaluated using various outcome values in young patients according to suture techniques. Read More

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November 2018
1 Read

A Collagen-coated Sponge Silk Scaffold for Functional Meniscus Regeneration.

J Tissue Eng Regen Med 2018 Nov 28. Epub 2018 Nov 28.

Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Zhejiang, China.

Tissue engineering is a promising solution for meniscal regeneration after meniscectomy. However, in situ reconstruction still poses a formidable challenge due to multifunctional roles of the meniscus in the knee. In this study, we fabricate a silk sponge from 9% (w/v) silk fibroin solution through freeze drying, and then coat its internal space and external surface with collagen sponge. Read More

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November 2018
1 Read

Deficiency of the pattern-recognition receptor CD14 protects against joint pathology and functional decline in a murine model of osteoarthritis.

PLoS One 2018 28;13(11):e0206217. Epub 2018 Nov 28.

Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania, United States of America.

Objective: CD14 is a monocyte/macrophage pattern-recognition receptor that modulates innate inflammatory signaling. Soluble CD14 levels in knee OA synovial fluids are associated with symptoms and progression of disease. Here we investigate the role of this receptor in development of OA using a murine joint injury model of disease. Read More

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November 2018
4 Reads

Microarray analysis of the molecular mechanisms associated with age and body mass index in human meniscal injury.

Mol Med Rep 2018 Nov 21. Epub 2018 Nov 21.

Department of Orthopedic Surgery, Shanghai Fifth People's Hospital Affiliated to Fudan University, Shanghai 200240, P.R. China.

The aim of the present study was to identify genes and functional pathways associated with meniscal injuries affected by age or body mass index (BMI) using microarray analysis. The GSE45233 gene expression dataset with 12 injured meniscus samples associated with age and BMI and GSE66635 dataset with 12 injured and 12 normal meniscus samples were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were identified based on age or BMI in GSE45233. Read More

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November 2018

Discoid meniscus in children and adolescents: Correlation between morphology and meniscal tears.

Rev Esp Cir Ortop Traumatol 2018 Nov 24. Epub 2018 Nov 24.

Departamento de Ortopedia y Traumatología Infantil, Sanatorio Allende, Córdoba, Argentina.

Background: Some authors have suggested that the diminished vascular blood supply, peripheral stability and thickness of the discoid meniscus (DM) would make it more prone to tears. The aims of this study are two-fold: 1) To analyse morphological characteristics by magnetic resonance (MRI), and 2) To correlate the size of the meniscus with the presence of meniscal tears.

Methods: The MRI of patients ≤18 years-old over a period of 5 years were reviewed, and patients with DM were identified. Read More

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November 2018

Transtibial pullout repair of medial meniscus posterior root tear restores physiological rotation of the tibia in the knee-flexed position.

Orthop Traumatol Surg Res 2018 Nov 24. Epub 2018 Nov 24.

Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikatacho, Kitaku, 700-8558 Okayama, Japan.

Background: Medial meniscus posterior root tear (MMPRT) results in joint overloading and degenerative changes in the knee. Favorable clinical outcomes have been reported after transtibial pullout repair of MMPRT. To date, however, in vivo tibial rotational changes before and after root repair remain poorly understood. Read More

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November 2018
1 Read

Severe Dry Eye With Combined Mechanisms is Involved in the Ocular Sequelae of SJS/TEN at the Chronic Stage.

Invest Ophthalmol Vis Sci 2018 Nov;59(14):DES80-DES86

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Stevens-Johnson syndrome (SJS), and its more severe variant, toxic epidermal necrolysis (TEN), are life-threatening diseases of the skin and mucous membranes. After the acute-stage damage subsides, serious visual impairment and severe dry eye remains as ocular sequelae. At the acute stage, ocular complications occur in 77% of SJS/TEN patients. Read More

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November 2018
6 Reads

Arthroscopic minimum saucerization and inferior-leaf meniscectomy for a horizontal tear of a complete discoid lateral meniscus: Report of two cases.

Int J Surg Case Rep 2018 Nov 22;53:372-376. Epub 2018 Nov 22.

Department of Orthopaedic Surgery, Hoshigaoka Medical Center, 4-8-1, Hoshigaoka, Hirakata, Osaka, 573-8511, Japan. Electronic address:

Introduction: Treatment of a horizontal tear of a complete discoid lateral meniscus (DLM) is still controversial. Preserving peripheral rim as a normal shape of the meniscus with single-leaf resection is a conventional treatment, however meniscal function could not be fully restored.

Presentation Of Case: A 28-year old woman and a 34-year old woman experienced knee pain and had restricted knee extension. Read More

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November 2018
1 Read

Incidence, Presentation, and Treatment of Pediatric and Adolescent Meniscal Root Injuries.

Orthop J Sports Med 2018 Nov 8;6(11):2325967118803888. Epub 2018 Nov 8.

Department of Orthopaedic Surgery, University of Texas Southwestern, Dallas, Texas, USA.

Background: Despite the increasing incidence of sports-related knee injuries in youth athletes, few studies have reported on the diagnosis and treatment of pediatric and adolescent meniscal root injuries.

Purpose: To describe traumatic posterior meniscal root injuries in a pediatric and adolescent population and compare the presentation of meniscal root injuries versus that of nonroot injuries.

Study Design: Cohort study; Level of evidence, 3. Read More

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November 2018
3 Reads

The Prevalence of Lower Eyelid Fornix Fat Prolapse: A Diagnostic Measure of Involutional Entropion.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):458-460

Norfolk and Norwich University Hospitals NHS Trust, Colney Lane, Norwich, NR4 7UY, United Kingdom.

Purpose: In our experience, lower lid involutional entropion is commonly associated with inferior fornix fat prolapse and non-eversion of the tarsal plate. We aimed to assess the prevalence of this sign as an early diagnostic indicator of lower lid involutional entropion in symptomatic and control groups.

Methods: Prospective, comparative, observational case series. Read More

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November 2018

[Clinical examination of the knee joint].

MMW Fortschr Med 2018 Nov;160(20):56-60

Muskuloskelettales Zentrum, Kliniken des Landkreises Neumarkt i. d. OPf., Neumarkt i. d. OPf., Deutschland.

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November 2018
2 Reads

Peripheral fixation of meniscal allograft does not reduce coronal extrusion under physiological load.

Knee Surg Sports Traumatol Arthrosc 2018 Nov 26. Epub 2018 Nov 26.

Fowler Kennedy Sport Medicine Clinic, Western University, London, Canada.

Purpose: Meniscal graft extrusion is a concern following meniscal allograft transplantation (MAT). MAT surgical techniques continue to evolve in an effort to reduce extrusion; however, improvements remain difficult to measure in vivo. A novel MRI-compatible in vitro loading device capable of applying physiologically relevant loads has been developed, allowing for the measurement of extrusion under a variety of controllable conditions. Read More

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November 2018
5 Reads

Screening utility of a rapid non-invasive dry eye assessment algorithm.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address:

Purpose: To evaluate the discriminative ability of a rapid non-invasive dry eye assessment algorithm (global evaluation component: SANDE questionnaire, and non-invasive tear film breakup time; subtype classification testing component: tear film lipid layer grade, and tear meniscus height) in detecting dry eye disease, as defined by the TFOS DEWS II diagnostic criteria.

Methods: Two hundred and thirty-five participants (77 male, 158 female), with a mean ± SD age of 43 ± 17 years, were recruited into a prospective diagnostic accuracy study. OSDI, DEQ-5, and SANDE dry eye symptomology scores; non-invasive tear film breakup time; absolute and inter-ocular differences in tear osmolarity; corneal, conjunctival, and lid margin staining scores; tear film lipid layer, meibum expressibility, meibomian gland orifice plugging, and eyelid margin telangiectasia grades; and tear meniscus height were evaluated in a single clinical session. Read More

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November 2018
3 Reads

Time-dependent dynamic behaviors of a confined liquid to achieve tailored adhesion force with repeated contacts revealed by an AFM.

Langmuir 2018 Nov 25. Epub 2018 Nov 25.

The adhesion forces between two silica surfaces were measured by using an atomic force microscope (AFM) with different experimental parameters in air to investigate the dynamic behavior of a confined liquid. Results show that the adhesion force is time-dependent and increases at first sharply and then slightly with dwell time until the saturation is reached, with a long equilibrium time. This behavior is well explained by a dynamic meniscus model, in which a liquid bridge grows gradually due to liquid film flow with a large viscosity. Read More

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November 2018
1 Read

Enhanced repair of meniscal hoop structure injuries using an aligned electrospun nanofibrous scaffold combined with a mesenchymal stem cell-derived tissue engineered construct.

Biomaterials 2018 Nov 13;192:346-354. Epub 2018 Nov 13.

Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita City, Osaka, 565-0871, Japan; Institute for Medical Science in Sports, Osaka Health Science University, 1-9-27 Tenma, Kita-ku, Osaka City, Osaka, 530-0043, Japan; Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita City, Osaka, 565-0871, Japan. Electronic address:

Damage to the meniscal hoop structure results in loss of biomechanical function, which potentially leads to the extrusion of the meniscus from the weight bearing area. However, there have been no established, effective treatments for such injuries. The purpose of this study was to investigate the applicability of cell-seeded nanofibrous scaffolds to repair the damaged meniscal hoop structure along with the prevention of subsequent cartilage degeneration using a rabbit model. Read More

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November 2018
4 Reads

Mountain ultramarathon results in temporary meniscus extrusion in healthy athletes.

Knee Surg Sports Traumatol Arthrosc 2018 Nov 21. Epub 2018 Nov 21.

Department of Orthopaedic Sports Medicine, Klinikum rechts der Isar, Ismaninger Str. 22, 81675, Munich, Germany.

Purpose: In recent literature medial meniscus extrusion (MME) was demonstrated as an age, BMI and load dependent physiological phenomenon in healthy knees. The aim of the present study was to evaluate the influence of mountain ultramarathon running on the medial meniscus extrusion (MME) in healthy athletes.

Methods: Healthy athletes of the 2017 Gore-Tex® Transalpine run (seven stages with in total 270. Read More

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November 2018
4 Reads

Arthroscopic Treatment of Lateral Elbow Pain Mimicking Lateral Epicondylitis: Long-term Follow-up of a Unique Surgical Protocol.

Tech Hand Up Extrem Surg 2018 Nov 19. Epub 2018 Nov 19.

Leni & Peter W. May Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.

Hypothesis And/or Background: The failure rate of extensor carpi radialis brevis debridement for refractory lateral epicondylitis is reported around 15%. Our novel arthroscopic treatment is predicated on the hypothesis that lateral epicondylitis is an intra-articular problem related to a variation of the capsule-meniscal anatomy that impinges on the radiocapitellar joint. We report long-term outcomes of 35 patients treated with a novel arthroscopic resection of their capsulosynovial fringe. Read More

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November 2018
2 Reads

Possible reparative effect of low-intensity pulsed ultrasound (LIPUS) on injured meniscus.

J Cell Commun Signal 2018 Nov 20. Epub 2018 Nov 20.

Advanced Research Center for Oral and Craniofacial Sciences (ARCOCS), Okayama University Dental School/Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.

Menisci are a pair of crescent-shaped fibrocartilages, particularly of which their inner region of meniscus is an avascular tissue. It has characteristics similar to those of articular cartilage, and hence is inferior in healing. We previously reported that low-intensity pulsed ultrasound (LIPUS) treatment stimulates the production of CCN2/CTGF, a protein involved in repairing articular cartilage, and the gene expression of major cartilage matrices such as type II collagen and aggrecan in cultured chondrocytes. Read More

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November 2018
2 Reads

Inflammatory molecules produced by meniscus and synovium in early and end-stage osteoarthritis: a coculture study.

J Cell Physiol 2018 Nov 19. Epub 2018 Nov 19.

RAMSES Laboratory, RIT Department, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

The aim of this study was to identify the molecules and pathways involved in the cross-talk between meniscus and synovium that may play a critical role in osteoarthritis (OA) pathophysiology. Samples of synovium and meniscus were collected from patients with early and end-stage OA and cultured alone or cocultured. Cytokines, chemokines, metalloproteases, and their inhibitors were evaluated at the gene and protein levels. Read More

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November 2018
4 Reads

Alignment factors affecting the medial meniscus extrusion increases the risk of osteoarthritis development.

Knee Surg Sports Traumatol Arthrosc 2018 Nov 19. Epub 2018 Nov 19.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Purpose: Varus alignment is known as one of the major causes of medial compartment osteoarthritis (OA). Medial meniscus extrusion also plays a critical role in the in the development of OA. However, studies on the exact relationship between alignment parameters and medial meniscus extrusion are limited. Read More

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November 2018

Septic arthritis caused by Staphylococcus caprae following arthroscopic meniscus tear repair in a patient without any foreign device.

Enferm Infecc Microbiol Clin 2018 Nov 16. Epub 2018 Nov 16.

Instituto de Investigación Sanitaria del Principado de Asturias, Spain; Servicio de Microbiología, Hospital Universitario Central de Asturias, Oviedo, Spain.

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November 2018
1 Read

Lateral Meniscal Posterior Root Repair With Anterior Cruciate Ligament Reconstruction Better Restores Knee Stability.

Am J Sports Med 2018 Nov 19:363546518808004. Epub 2018 Nov 19.

Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Background:: The effect of lateral meniscal posterior root tear and repair-commonly seen in clinical practice in the setting of anterior cruciate ligament (ACL) reconstruction-is not known.

Purpose/hypothesis:: This study evaluated the effect of tear and repair of the lateral meniscal posterior root on the biomechanics of the ACL-reconstructed knee. It was hypothesized that anterior tibial translation would increase under anterior loading and simulated pivot-shift loading with the root tear of the posterior lateral meniscus, while repair of the root tear would reduce it close to the noninjured state. Read More

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November 2018
8 Reads

Correlation of Meniscal Tear with Timing of Anterior Cruciate Ligament Reconstruction in Patients without Initially Concurrent Meniscal Tear.

J Knee Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.

The incidence of meniscal tear was reported to increase with the delay of anterior cruciate ligament reconstruction (ACLR). The tear may occur concurrently with the ACL injury or after the ACL injury. Few studies had focused on the patients whose meniscus is intact during ACL injury. Read More

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November 2018
5 Reads

Regional gene expression analysis of multiple tissues in an experimental animal model of post-traumatic osteoarthritis.

Osteoarthritis Cartilage 2018 Nov 16. Epub 2018 Nov 16.

Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, United States; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, United States. Electronic address:

Objective: To characterize local disease progression of the medial meniscus transection (MMT) model of post-traumatic osteoarthritis (OA) at the molecular level, in order to establish a baseline for therapeutic testing at the preclinical stage.

Design: Weight-matched male Lewis rats underwent MMT or sham surgery on the left limb with the right leg as contralateral control. At 1 and 3 weeks post-surgery, tissues were harvested from different areas of the articular cartilage (medial and lateral tibial plateaus, and medial osteophyte region) and synovium (medial and lateral), and analyzed separately. Read More

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November 2018
3 Reads

Biomechanical evaluation of opening-wedge high tibial osteotomy with composite materials using finite-element analysis.

Knee 2018 Dec 13;25(6):977-987. Epub 2018 Nov 13.

Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. Electronic address:

Background: Medial opening-wedge high tibial osteotomy (HTO) has been used to treat osteoarthritis of the medial compartment of the knee. However, this makes the proximal tibia a highly unstable structure and causes the plate to be a potential source of mechanical failure. Consequently, proper design and material use of the fixation device are essential in HTO, especially for overweight or full-weight-bearing patients. Read More

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December 2018
5 Reads