722 results match your criteria Meningococcemia


Temporary Diverting End-Colostomy in Critically Ill Children with Severe Perianal Wound Infection.

Adv Skin Wound Care 2021 Jun;34(6):322-326

At the Ankara University School of Medicine, Turkey, Emrah Gün, MD, is Fellow, Department of Pediatric Critical Care Medicine; Tanil Kendirli, MD, is Professor, Department of Pediatric Critical Care Medicine; Edin Botan, MD, is Fellow, Department of Pediatric Critical Care Medicine; Halil Özdemir, MD, is Associate Professor, Department of Pediatric Infectious Disease; Ergin Çiftçi, MD, is Professor, Department of Pediatric Infectious Disease; Kübra Konca, MD, is Fellow, Department of Pediatric Infectious Disease; Meltem Koloğlu, MD, is Professor, Department of Pediatric Surgery; Gülnur Göllü, MD, is Associate Professor, Department of Pediatric Surgery; Özlem Selvi Can, MD, is Associate Professor, Department of Pediatric Anesthesia; Ercan Tutar, MD, is Professor, Department of Pediatric Cardiology; Ahmet Rüçhan Akar, MD, is Professor, Department of Cardiovascular Surgery, Heart Center, Cebeci Hospitals; and Erdal İnce, MD, is Professor, Department of Pediatric Infectious Disease. Acknowledgments: The authors wish to thank all the pediatric ICU nursing staff for all their efforts and support for our critically ill pediatric patients. The authors have disclosed no financial relationships related to this article. Submitted June 24, 2020; accepted in revised form September 25, 2020.

Abstract: Broad and deep perianal wounds are challenging in both adult and pediatric ICUs. These wounds, if contaminated with gastrointestinal flora, can cause invasive sepsis and death, and recovery can be prolonged. Controlling the source of infection without diverting stool from the perianal region is complicated. Read More

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Investigation of primary immune deficiency after severe bacterial infection in children: A population-based study in western France.

Arch Pediatr 2021 Apr 23. Epub 2021 Apr 23.

CHU de Nantes, Department of Pediatrics, Nantes, France.

Background: Infectious diseases are still an important cause of morbidity and mortality in high-income countries and may preferentially affect predisposed children, especially immunocompromised children. We aimed to evaluate the frequency of recommended immunological tests in children with community-onset severe bacterial infection (COSBI) admitted to a pediatric intensive care unit. We also assessed the frequency and described the typology of diagnosed primary immune deficiency (PID). Read More

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Fatal Serogroup B Meningococcemia in a Child Previously Vaccinated With MenACWY-DT Vaccine.

Clin Pediatr (Phila) 2021 May;60(4-5):259-260

Medical School of Ege University, Division of Infectious Disease, Department of Pediatrics, Izmir, Turkey.

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Meningococcal disease epidemiology in Brazil (2005-2018) and impact of MenC vaccination.

Vaccine 2021 01 24;39(3):605-616. Epub 2020 Dec 24.

GSK, Rio de Janeiro, RJ, Brazil.

Background: Meningococcal disease (MD) presents a substantial public health problem in Brazil. Meningococcal C conjugate (MenC) vaccination was introduced into the routine infant immunization program in 2010, followed by adolescent vaccination in 2017. We evaluated changes in national and regional MD incidence and mortality between 2005 and 2018, serogroup distribution and vaccine coverage. Read More

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January 2021

Neonatal meningococcal disease: an update.

J Matern Fetal Neonatal Med 2020 Nov 24:1-6. Epub 2020 Nov 24.

Department of Paediatrics, Patras Medical School, University of Patras , Patras , Greece.

is a common cause of sepsis in the pediatric population but is only rarely observed in neonates. The true incidence of the disease in that age group remains undefined. The purpose of this review is to summarize the published data on meningococcal disease in the neonatal period. Read More

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November 2020

Pediatric bacterial meningitis and meningococcal disease profile in a Brazilian General Hospital.

Braz J Infect Dis 2020 Jul - Aug;24(4):337-342. Epub 2020 Jun 26.

Universidade de São Paulo, Hospital Universitário, Departamento de Pediatria, São Paulo, SP, Brazil. Electronic address:

Objective: To evaluate the clinical and epidemiological profile of bacterial meningitis and meningococcal disease in pediatric patients admitted to a Brazilian Secondary Public Hospital.

Methods: A descriptive observational study was conducted. Microbiologically proven bacterial meningitis or meningococcal disease diagnosed from 2008 to 2018 were included. Read More

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October 2020

Meningococcal Infections in Children and Adolescents: Update and Prevention.

Authors:
Rebecca C Brady

Adv Pediatr 2020 08 14;67:29-46. Epub 2020 May 14.

Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 6014, Cincinnati, OH 45229-3039, USA. Electronic address:

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Surgical Treatment of Vitreoretinal Complications During Disseminated Intravascular Coagulation Secondary to Meningococcemia.

Retin Cases Brief Rep 2020 Jun 15. Epub 2020 Jun 15.

Department of Ophthalmology, Percy Military Hospital, 101 Avenue H. Barbusse, 92141 Clamart, France. Tel: +331.41.46.62.74. Fax : +331.41.46.64.91.

Purpose: To report a case of the surgical management of vitreoretinal complications during disseminated intravascular coagulation (DIC) secondary to meningococcemia.

Methods: Case report.

Results: A 25-year-old man presented with loss of vision due to retinal and vitreous hemorrhages during DIC secondary to meningococcemia. Read More

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Chronic meningococcemia in a vertically HIV-infected adolescent.

IDCases 2020 21;20:e00764. Epub 2020 Apr 21.

Pediatric Infectious Disease Clinical Care Center of Federal University of São Paulo, Pedro de Toledo Street 924/928 Vila Clementino, Zip Code 04039-002, São Paulo, SP, Brazil.

Chronic meningococcemia is a rare manifestation of meningococcal disease, characterized by a period of more than one week of intermittent or continuous fever, arthralgia and skin lesions without meningitis. It can occur both in previously healthy and immunocompromised patients. The gold standard for the diagnosis is culture isolation of in sterile material. Read More

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A severe course of serogroup W meningococcemia in a patient with infantile nephropathic cystinosis.

Hum Vaccin Immunother 2020 11 13;16(11):2787-2788. Epub 2020 May 13.

Faculty of Medicine, Department of Pediatric Intensive Care, Eskisehir Osmangazi University , Eskisehir, Turkey.

We present a 9-month old boy with cystinosis admitted to our hospital with the complaints of vomiting, diarrhea and seizure. While he was hospitalized in a pediatric intensive care unit due to worsening of his signs related to cystinosis, within hours, he suffered complications of septic shock, acute renal failure, and disseminated intravascular coagulation, due to invasive serogroup W disease. Our patient is the first reported case of invasive meningococcal disease with cystinosis. Read More

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November 2020

Meningococcemia Due to Nongroupable Neisseria meningitidis in a Splenectomized Child.

Pediatr Infect Dis J 2020 05;39(5):e57

Health Sciences University Ankara Hematology and Oncology Research Hospital, Department of Pediatric Infectious Diseases, Ankara, Turkey.

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Purpuric Epiglottic Lesion in Purpura Fulminans Form of Meningococcemia.

Ear Nose Throat J 2020 Apr 15:145561320920432. Epub 2020 Apr 15.

Department of Pediatric Infectious Diseases, Ankara University School of Medicine, Ankara, Turkey.

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Induced Fatal Waterhouse-Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure.

Brain Sci 2020 Mar 17;10(3). Epub 2020 Mar 17.

Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.

-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate. In patients with a fulminant infection, a maculopapular petechial eruption, purpura fulminans, or an ecchymotic lesion are worrisome signs reflecting disseminated intravascular coagulation (DIC) and hint at Waterhouse-Friderichsen syndrome (WFS). Here, we describe a rare case of a patient with a fulminant induced acute systemic meningococcal disease presenting with high-grade fever without meningitis symptoms. Read More

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The Inflammatory and Hemostatic Response in Sepsis and Meningococcemia.

Crit Care Clin 2020 Apr 30;36(2):391-399. Epub 2020 Jan 30.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. Electronic address:

Meningococcemia is notorious for evasion of the host immune system and its rapid progression to fulminant disease, and serves as a unique model for pediatric sepsis. Illness severity is determined by complex interplays among host, pathogen, and environment. The inflammatory host response, including proinflammatory and anti-inflammatory responses in innate and adaptive immunity, skews toward a proinflammatory state. Read More

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[Meningococcemia: Different Serotypes in the Same Region].

Mikrobiyol Bul 2020 Jan;54(1):163-170

Ministry of Health, General Directorate of Public Health, National Respiratory Pathogens Reference Laboratory, Ankara, Turkey.

Meningococcal infections are important health problems causing high morbidity and mortality. Neisseria meningitidis have 13 serogroups. A, B, C, Y and W135 are the most common causes of invasive disease among those serogroups. Read More

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January 2020

Acute abdominal pain as the initial manifestation of meningococcemia in adult patient.

Enferm Infecc Microbiol Clin (Engl Ed) 2020 May 14;38(5):247-248. Epub 2019 Nov 14.

Servicio de Medicina Interna, Hospital Universitario San Juan de Alicante, Spain; Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), Spain.

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First case report of fulminant septic shock from meningococcemia associated with Cryptococcus neoformans coinfection in an immunocompetent patient.

Med Mycol Case Rep 2019 Dec 3;26:44-46. Epub 2019 Oct 3.

Infectious Disease Department, Hans Dieter Schmidt Regional Hospital, Joinville, SC, Brazil.

The meningococcal disease manifestation associated with the presence of is rare. There are no reports in the literature about these simultaneous infections in immunocompetent patients. The aim of the present study is to describe the first case of fulminant septic shock by associated with coinfection in an immunocompetent patient. Read More

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December 2019

A case report of multiple cerebral abscess formation complicating serogroup B Neisseria meningitidis meningitis.

BMC Infect Dis 2019 Oct 21;19(1):863. Epub 2019 Oct 21.

Department of Infectious Diseases, Temple Street Children's University Hospital, Dublin 1, Ireland.

Background: Invasive meningococcal disease (IMD) presenting with meningitis causes significant mortality and morbidity. Suppurative complications of serogroup B meningococcal sepsis are rare and necessitate urgent multidisciplinary management to mitigate long-term morbidity or mortality.

Case Presentation: We present a rare case of invasive meningococcal disease in a 28-month old boy complicated by multiple abscess formation within a pre-existing antenatal left middle cerebral artery territory infarct. Read More

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October 2019

Analysis of social and medical portrait of children with pertussis, meningococcal infectious, scarlet fever and estimation of their assigned pharmacotherapy.

Wiad Lek 2019 ;72(9 cz 2):1802-1808

Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.

Objective: Introduction: The level of childhood bacterial diseases incidence does not have a downward trend. The aim: Conduction of a sociological analysis of medical cards for children with pertussis, meningococcal infection (MI), scarlet fever, and evaluation of consumed pharmacotherapy according to real clinical practice in Ukraine.

Patients And Methods: Materials and methods: 1215 medical cards of inpatients; methods: sociological - document analysis, retrospective frequency. Read More

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November 2019

Purpura in the Emergency Room: Two Cases of Sepsis with Cutaneous Manifestations.

Cureus 2019 Jun 23;11(6):e4976. Epub 2019 Jun 23.

Emergency Medicine, AdventHealth East Orlando, Orlando, USA.

Purpura fulminans is a seldom seen manifestation of sepsis in the emergency department (ED). The morbidity and mortality of sepsis have been widely studied and reported; the hallmark of treatment is early recognition and intervention. In extreme cases, sepsis can cause widespread activation of the coagulation cascade further complicating the treatment and recovery from the causative pathogen. Read More

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50 Years Ago in TheJournal ofPediatrics: Heparin Therapy in Fulminant Meningococcemia.

J Pediatr 2019 09;212:207

Rainbow Babies and Children's Hospital, Cleveland, Ohio.

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September 2019

Myocarditis in fulminant meningococcemia.

Authors:
Hanyu Qin Wei Jiang

Intensive Care Med 2019 11 27;45(11):1655-1656. Epub 2019 May 27.

Medical Intensive Care Unit, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

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November 2019

Primary Meningococcal Septic Arthritis Case Report and Literature Review of an Unusual Manifestation of Meningococcal Disease.

Bull Hosp Jt Dis (2013) 2019 Mar;77(2):140-145

Introduction: Primary meningococcal septic arthritis (PMSA) is an unusual manifestation of meningococcal disease. It is defined as the presence of acute septic arthritis without association with meningitis or the classic meningococcemia and isolation of Neisseria meningitidis in synovial fluid and blood culture. Diagnosis and early treatment, combining antibiotic and joint drainage, are fundamental. Read More

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Epidemiological burden of meningococcal disease in Latin America: A systematic literature review.

Int J Infect Dis 2019 Aug 11;85:37-48. Epub 2019 May 11.

Medical and Scientific Affairs, Pfizer Vaccines, Buenos Aires, Argentina.

Objective: To evaluate the epidemiological profile of invasive meningococcal disease (IMD), meningococcal meningitis, and Neisseria meningitidis carriers in Latin America.

Methods: A systematic review was conducted to identify and analyze studies published in 2008-2018. Incidence rates, case fatality rates (CFRs), and the relative distribution of cases per serogroup by country were assessed. Read More

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The rash with maculopapules and fever in children.

Clin Dermatol 2019 Mar - Apr;37(2):119-128. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

Several medical conditions can cause children to present with fever and a maculopapular rash Although some presentations are benign, others may be medical emergencies, which warrant a prompt diagnosis. We review some of the more common causes of fever and maculopapular dermatitirs, rash including infectious processes (roseola; rubeola; rubella; parvovirus B19; hand, foot, and mouth disease; scarlet fever; meningococcemia; Epstein-Barr virus infection), hypersensitivity reactions (exanthematous drug reactions), and vasculitis syndromes (Kawasaki disease). We have included a diagnostic algorithm to facilitate rapid identification of the etiology of the rash and fever. Read More

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September 2019

The rash with maculopapules and fever in adults.

Clin Dermatol 2019 Mar - Apr;37(2):109-118. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

There is a broad differential diagnosis for the presentation of fever and maculopapular rash in an adult. Although some causative conditions are benign, others are medical emergencies that require prompt diagnosis. We describe various conditions that result in a fever and maculopapular rash in adults. Read More

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September 2019

Chronic meningococcemia.

IDCases 2019 2;15:e00502. Epub 2019 Feb 2.

Infectious Diseases Department, Centro Hospitalar Universitário de São João, Alameda Professor Hernani Monteiro, 4200-319, Porto, Portugal.

The spectrum of -associated clinical entities involves mild forms of disease, without neurological involvement or sepsis, and asymptomatic carrier states. Rarely, bacteremia can be associated with a prolonged fever with or without arthritis, which we designate as chronic meningococcemia. Chronic meningococcemia is an uncommon entity, usually associated to serogroup B . Read More

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February 2019

First Report of a Disease by Rhazes 10 Centuries Ago.

Int J Prev Med 2019 15;10. Epub 2019 Jan 15.

Department of Anesthesiology and Intensive Care Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Introduction: Abu Bakr Mohammad Ibn Zakariya Al-Razi (865-925 CE), who was known as "Rhazes" in the west, was a famous scientist of medieval ages. He has more than 200 books and treatises. His masterpiece on medicine "" contains around 900 case reports. Read More

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January 2019

The Pathogenic Neisseria Use a Streamlined Set of Peptidoglycan Degradation Proteins for Peptidoglycan Remodeling, Recycling, and Toxic Fragment Release.

Front Microbiol 2019 31;10:73. Epub 2019 Jan 31.

Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.

and release peptidoglycan (PG) fragments from the cell as the bacteria grow. For these PG fragments are known to cause damage to human Fallopian tube tissue in organ culture that mimics the damage seen in patients with pelvic inflammatory disease. also releases pro-inflammatory PG fragments, but in smaller amounts than those from . Read More

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January 2019