319 results match your criteria Meningioma Optic Nerve Sheath


Interdural course of the ophthalmic artery in the optic canal.

J Neurosurg 2019 Jan 4:1-7. Epub 2019 Jan 4.

1Division of Neurological Surgery and.

OBJECTIVEIn the current neurosurgical and anatomical literature, the intracanalicular segment of the ophthalmic artery (OphA) is usually described to be within the optic nerve dural sheath (ONDS), implying direct contact between the nerve and the artery inside the optic canal. In the present study, the authors sought to clarify the exact relationship between the OphA and ONDS.METHODSTen cadaveric heads were subjected to endoscopic endonasal and transcranial exposures of the OphA in the optic canal (5 for each approach). Read More

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http://dx.doi.org/10.3171/2018.6.JNS18856DOI Listing
January 2019

Long-term efficacy of fractionated conformal radiotherapy for the management of primary optic nerve sheath meningioma.

Br J Ophthalmol 2018 Dec 20. Epub 2018 Dec 20.

Wilmer Eye Institute Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Background/aim: Fractionated conformal radiotherapy (FCRT) is now used to treat vision-threatening optic nerve sheath meningioma (ONSM), but long-term efficacy and safety data are lacking; the purpose of this study was to assess these key data.

Methods: This is a retrospective chart review with prospective follow-up of adult patients treated with FCRT for primary ONSM at four academic medical centres between 1995 and 2007 with ≥10 years of follow-up after treatment.

Results: 16 patients were identified with a mean post-treatment follow-up of 14. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2018-313135DOI Listing
December 2018
4 Reads

Optic nerve orbital meningioma.

Cesk Slov Oftalmol 2018 ;74(1):23-30

Introduction: Orbital meningioma treatment has achieved significant success over the last period. Primary optic nerve sheath meningiomas by the clinically progressive finding, but still persistent sufficient visual acuity, can be treated by fractionated stereotactic radiotherapy. Surgery is indicated for secondary meningiomas of the orbit. Read More

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January 2018

Solitary fibrous tumor/hemangiopericytoma of the optic canal.

Clin Neuropathol 2019 Mar/Apr;38(2):74-79

Solitary fibrous tumor/hemangiopericytoma seldom arises from the optic nerve sheath. Herein, we describe the clinical, radiological, and histological findings of a solitary fibrous tumor/hemangiopericytoma arising from the optic nerve sheath and occupying the optic canal. The diagnosis is challenging both clinically and histologically as it clinically simulates a commoner lesion, i. Read More

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http://dx.doi.org/10.5414/NP301127DOI Listing
February 2019
2 Reads

Optic nerve sheath meningiomas: prevalence, impact, and management strategies.

Eye Brain 2018 24;10:85-99. Epub 2018 Oct 24.

Sydney Medical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, NSW, Australia,

Optic nerve sheath meningiomas are rare benign neoplasms of the meninges surrounding the optic nerve. They are a significant cause of morbidity. While the mortality rate is practically zero, these tumors can blind or disfigure patients. Read More

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http://dx.doi.org/10.2147/EB.S144345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207092PMC
October 2018
1 Read

A novel surgical approach for intraorbital optic nerve tumors.

J Clin Neurosci 2019 Jan 6;59:362-366. Epub 2018 Nov 6.

Department of Neurosurgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.

Although orbital tumors involving the optic nerve are rare, it is well-known that they are very likely to cause serious visual impairment in a patient. Unfortunately, at present, there are no effective interventions that can reliably preserve visual function while controlling tumor growth into intracranial spaces. To ensure visual function of the non-affected side, transection of the optic nerve together with the tumors involved is necessary in some cases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183105
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http://dx.doi.org/10.1016/j.jocn.2018.10.126DOI Listing
January 2019
9 Reads

The Use of Ga-DOTATATE PET/CT in the Non-invasive Diagnosis of Optic Nerve Sheath Meningioma: A Case Report.

Front Oncol 2018 16;8:454. Epub 2018 Oct 16.

Division of Radiation Oncology, Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

We hereby report the case of a patient with optic nerve sheath meningioma (ONSM), whose diagnosis and multidisciplinary management was guided by the use of Gallium-68 (Ga)-labeled dodecanetetraacetic acid-tyrosine-3-octreotate (DOTATATE) positron emission tomography (PET)/computed tomography (CT) scan. We briefly review the diagnosis and management of ONSM, and review the literature on the role and current status of nuclear imaging with somatostatin receptor ligands in the non-invasive diagnosis and management of meningiomas. Read More

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https://www.frontiersin.org/article/10.3389/fonc.2018.00454/
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http://dx.doi.org/10.3389/fonc.2018.00454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198069PMC
October 2018
4 Reads

Intra-Orbital Meningioma Causing Loss of Vision in Neurofibromatosis Type 2: Case Series and Management Considerations.

Front Surg 2018 9;5:60. Epub 2018 Oct 9.

Department of Radiology, USC Keck School of Medicine, Los Angeles, CA, United States.

Little evidence exists regarding the management of orbital meningioma causing vision loss in the setting of neurofibromatosis Type 2 (NF2). We review here our experience with patients at risk for blindness due to intra-orbital meningioma. The charts of patients with NF2 presenting for evaluation of intra-orbital meningioma and vision impairment between 2008 and 2013 were retrospectively reviewed in accordance with institutional IRB policies. Read More

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https://www.frontiersin.org/article/10.3389/fsurg.2018.00060
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http://dx.doi.org/10.3389/fsurg.2018.00060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189417PMC
October 2018
8 Reads

Prognostic factors in the surgical treatment of intracanalicular primary optic nerve sheath meningiomas.

J Neurosurg 2018 Sep 1:1-8. Epub 2018 Sep 1.

Departments of1Neurosurgery and.

OBJECTIVEAlthough meningiomas frequently involve the optic nerve, primary optic nerve sheath meningiomas (ONSMs) are rare, accounting for only 1% of all meningiomas. Given the high risk of vision loss with these tumors, surgical intervention is seldom considered, and radiation or observation is commonly applied. Here, the authors describe the visual outcomes for a series of patients who were treated with surgery aiming at maximal tumor resection and highlight their prognostic factors. Read More

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http://dx.doi.org/10.3171/2018.4.JNS173080DOI Listing
September 2018
8 Reads

[Clinical analysis of orbital ectopic meningiomas].

Zhonghua Yan Ke Za Zhi 2018 Sep;54(9):665-670

Tianjin Medical University Eye Hospital, College of Optometry and Ophthalmology, Tianjin Medical University Eye Institute, Tianjin 300384, China.

To investigate the clinical features, imaging features, diagnoses and therapeutic regimens of orbital ectopic meningiomas. A retrospective study. All the clinical data of 10 patients (10 eyes) with orbital ectopic meningiomas were analyzed retrospectively from August 1999 to October 2016. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.09.006DOI Listing
September 2018
3 Reads

Optic nerve sheath meningioma.

Clin Exp Optom 2018 Jul 28. Epub 2018 Jul 28.

Department of Optometry, University of Michigan Kellogg Eye Center, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1111/cxo.12819DOI Listing
July 2018
2 Reads

Modern Management of Meningiomas Compressing the Optic Nerve: A Systematic Review.

World Neurosurg 2018 Oct 3;118:e677-e686. Epub 2018 Aug 3.

Department of Neurosurgery, Rennes University Hospital, Rennes, France; Rennes 1 University, Faculty of Medicine, Rennes Cedex, France.

Objective: Meningiomas that compress the optic nerve (ON) can lead to different visual outcomes depending on the segment of ON affected (intraorbital, canalicular, and intracranial). In this study, we performed a comprehensive comparison of the management options (surgery, radiation, or observation alone) for meningiomas compressing the ON, categorized by location and relation to the ON.

Methods: MEDLINE, EMBASE, Web of Science, and the Cochrane Database of Systematic reviews databases were searched according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.020DOI Listing
October 2018
14 Reads

Teaching NeuroImages: Optic nerve sheath meningioma presenting as gaze-evoked amaurosis.

Neurology 2018 Jun;90(23):e2095-e2096

From the Departments of Neurology (S.A.A.J., J.J.C., W.O.T.) and Ophthalmology (J.J.C.), Mayo Clinic Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000005642DOI Listing
June 2018
2 Reads

Ultra-Early Optic Nerve Decompression for the Resection of Anterior Clinoidal Meningioma.

J Neurol Surg B Skull Base 2018 Feb 18;79(Suppl 2):S231-S232. Epub 2018 Jan 18.

Department of Neurosurgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.

Improvement in vision is one of the main goals of surgery for anterior clinoidal meningiomas with visual deficits. Early optic nerve decompression surgery has been advocated in previous studies to achieve the best visual outcome. Through this video, the authors describe their surgical techniques to decompress the optic nerve at the very early stage of surgery. Read More

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http://dx.doi.org/10.1055/s-0038-1623521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954281PMC
February 2018
3 Reads

Malignant Orbital Meningioma Originating from the Frontal Lobe.

Ocul Oncol Pathol 2018 Apr 10;4(3):186-190. Epub 2017 Nov 10.

Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA.

Purpose Of The Study: Orbital meningiomas are typically benign tumors, most commonly originating from the dura of the sphenoid wing or the optic nerve sheath.

Procedures: We describe an unusual case of a malignant meningioma originating from the frontal lobe that ultimately produced orbital and distant metastases.

Results And Conclusions: Orbital invasion by the meningioma was preceded by multiple incomplete resections, which may have facilitated access to the orbit. Read More

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http://dx.doi.org/10.1159/000481509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939669PMC
April 2018
7 Reads

Early intervention using high-precision radiotherapy preserved visual function for five consecutive patients with optic nerve sheath meningioma.

Int J Clin Oncol 2018 Oct 30;23(5):826-834. Epub 2018 Apr 30.

Miyakojima IGRT Clinic, Osaka, Japan.

Background: There has been a paradigm shift in the treatment for optic nerve sheath meningioma (ONSM) from surgery to fractionated stereotactic radiotherapy (FSRT) in other countries. However, FSRT has seldom been performed in Japan. The purpose of this retrospective study is to reconfirm the effectiveness of early intervention with precision radiotherapy for ONSM reported in our previous study. Read More

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http://dx.doi.org/10.1007/s10147-018-1284-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154112PMC
October 2018
4 Reads

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.

Am J Med Genet A 2018 05;176(5):1258-1269

Hereditary Cancer Group, The Institute for Health Science Research Germans Trias i Pujol (IGTP)-PMPPC, Barcelona, Spain.

Organized and hosted by the Children's Tumor Foundation (CTF), the Neurofibromatosis (NF) conference is the premier annual gathering for clinicians and researchers interested in neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN). The 2016 edition constituted a blend of clinical and basic aspects of NF research that helped in clarifying different advances in the field. The incorporation of next generation sequencing is changing the way genetic diagnostics is performed for NF and related disorders, providing solutions to problems like genetic heterogeneity, overlapping clinical manifestations, or the presence of mosaicism. Read More

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http://dx.doi.org/10.1002/ajmg.a.38675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918269PMC
May 2018
15 Reads

Optic Nerve Sheath Meningioma: Preliminary Analysis of the Role of Radiation Therapy.

Brain Tumor Res Treat 2018 Apr 2;6(1):8-12. Epub 2018 Apr 2.

Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The purpose of this study was to evaluate the treatment outcome of our optic nerve sheath meningioma (ONSM) case series in terms of preventing tumor growth and preserving vision in ONSM patients.

Methods: Between July 2003 and March 2015, 1,398 patients with intracranial meningioma were diagnosed at Seoul National University Bundang Hospital. Among them, only 13 patients (0. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932300PMC
April 2018
7 Reads

Single- and Multi-Fraction Stereotactic Radiosurgery Dose Tolerances of the Optic Pathways.

Int J Radiat Oncol Biol Phys 2018 Jan 31. Epub 2018 Jan 31.

Department of Radiation Oncology, Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina.

Purpose: Dosimetric and clinical predictors of radiation-induced optic nerve/chiasm neuropathy (RION) after single-fraction stereotactic radiosurgery (SRS) or hypofractionated (2-5 fractions) radiosurgery (fSRS) were analyzed from pooled data that were extracted from published reports (PubMed indexed from 1990 to June 2015). This study was undertaken as part of the American Association of Physicists in Medicine Working Group on Stereotactic Body Radiotherapy, investigating normal tissue complication probability (NTCP) after hypofractionated radiation.

Methods And Materials: Eligible studies described dose delivered to optic nerve/chiasm and provided crude or actuarial toxicity risks, with visual endpoints (ie, loss of visual acuity, alterations in visual fields, and/or blindness/complete vision loss). Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.01.053DOI Listing
January 2018
7 Reads

Orbital malignant meningioma: a unique presentation of a rare entity.

Orbit 2018 Feb 27:1-6. Epub 2018 Feb 27.

a Department of Ophthalmology , The George Washington University School of Medicine and Health Sciences , Washington , DC , USA.

An elderly female with progressive proptosis was found to have an aggressive retrobulbar solid orbital mass. The mass was distinct from the optic nerve sheath and intracranial meninges, and produced concave erosion of the sphenoid wing. Operative findings demonstrated an orbital mass adherent to the dura of the superior orbital fissure. Read More

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http://dx.doi.org/10.1080/01676830.2018.1437189DOI Listing
February 2018
1 Read

Rapid recovery of vision following early intervention with fractionated stereotactic radiotherapy for optic nerve sheath meningioma.

Int Med Case Rep J 2018 30;11:17-22. Epub 2018 Jan 30.

Department of Neuro-Ophthalmological Therapeutics, Hyogo College of Medicine, Nishinomiya, Japan.

Purpose: To report the outcomes of early intervention with fractionated stereotactic radiotherapy (FSRT) in a patient with primary optic nerve sheath meningioma (ONSM).

Patient And Methods: A male patient in his early 40s underwent 5-beam FSRT at a prescribed dose of 50 Gy in 25 fractions over 35 days. The patient had an 11-month history of progressive visual impairment at the time of FSRT. Read More

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http://dx.doi.org/10.2147/IMCRJ.S149592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796469PMC
January 2018
4 Reads

Monitoring of optic nerve function in Neurofibromatosis 2 children with optic nerve sheath meningiomas using multifocal visual evoked potentials.

J Clin Neurosci 2018 Apr 3;50:262-267. Epub 2018 Feb 3.

Save Sight Institute Discipline of Ophthalmology, The University of Sydney, Australia.

Monitoring optic nerve sheath meningiomas (ONSM) in Neurofibromatosis type 2 (NF2) patients remains difficult. Other ocular manifestations of NF2 may obscure ophthalmic assessment of optic nerve function in these patients. Serial magnetic resonance imaging (MRI) used to assess the optic nerve is not without limitations, being expensive and often requiring general anaesthetic in children, with associated risks. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.01.012DOI Listing
April 2018
8 Reads

Optic Nerve Meningioma Mimicking Cavernous Hemangioma.

World Neurosurg 2018 Feb 28;110:301-302. Epub 2017 Nov 28.

Department of Radiology, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France. Electronic address:

A 38-year-old woman presented with rapidly worsening, painless right monocular vision loss. An examination revealed a visual acuity of 1.4/10 and a central scotoma in the right eye. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.11.107DOI Listing
February 2018
7 Reads

Analysis of petrous apex meningocele associated with meningioma: is there any relation with chronic intracranial hypertension?

Neuroradiology 2018 Feb 29;60(2):151-159. Epub 2017 Nov 29.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, People's Republic of China.

Purpose: Petrous apex meningocele (PAM) is an uncommon cystic lesion involving the petrous apex. The underlying cause of PAM may be related to chronic elevated intracranial pressure. The aim of the study was to explore the relationship between PAM and meningioma and between PAM and other intracranial hypertension findings. Read More

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http://dx.doi.org/10.1007/s00234-017-1932-xDOI Listing
February 2018
9 Reads

Natural history of primary paediatric optic nerve sheath meningioma: case series and review.

Br J Ophthalmol 2018 Aug 16;102(8):1147-1153. Epub 2017 Nov 16.

Department of Ophthalmology, South Australian Institute of Ophthalmology, Adelaide, South Australia, Australia.

Purpose: To study the natural history, clinical and radiological characteristics of primary paediatric optic nerve sheath meningioma (PPONSM).

Methods: Retrospective study of eight paediatric patients who were treated between 1994 and 2016 at the University Hospital Zurich, Switzerland and the Royal Adelaide Hospital, Australia. Clinical records and imaging studies were reviewed. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2017-310672DOI Listing
August 2018
60 Reads
2.980 Impact Factor

Retrospective chart review of the use of imaging and biopsy in the diagnosis of optic nerve sheath meningiomas and intra-conal orbital lymphomas at a single institution.

Orbit 2017 Dec 16;36(6):392-396. Epub 2017 Aug 16.

a Department of Ophthalmology , University of Kansas School of Medicine, Prairie Village, Kansas, USA.

Optic nerve sheath meningiomas (ONSM) and intra-conal orbital lymphomas are common entities on the differential of a retrobulbar optic nerve involving space-occupying lesion. In this study, we compare the pre-surgical diagnosis, based on clinical presentation and neuroimaging, to the surgical pathology results of intra-conal orbital lymphomas and ONSM. This is an IRB approved retrospective chart review of orbital lymphomas and optic nerve sheath meningiomas biopsied by a single surgeon over a 4-year period at a single institution. Read More

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http://dx.doi.org/10.1080/01676830.2017.1337198DOI Listing
December 2017
15 Reads

Ectopic orbital meningioma: Fact or fiction?

Orbit 2017 Jun 3;36(3):144-146. Epub 2017 Mar 3.

a Oxford Eye Hospital , Oxford University Hospital NHS Trust , Oxford , United Kingdom.

Primary intraorbital ectopic meningiomas are rare and their existence remains controversial. We present a 30-year-old female with painless, non-axial proptosis and a palpable superomedial mass. The MRI demonstrated that the mass had no optic nerve sheath or sphenoid wing involvement and was initially reported to have no intracranial extension. Read More

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http://dx.doi.org/10.1080/01676830.2017.1279663DOI Listing
June 2017
28 Reads

[A plasminogen regulation system in brain tumors].

Zh Vopr Neirokhir Im N N Burdenko 2017;81(2):22-27

Rostov Cancer Research Institute, Rostov-on-Don, Russia.

Introduction: Tumor progression and neovascularization during malignant processes are believed to be associated with plasminogen activators and the PAI-1 inhibitor, but their role and interactions in various types of brain tumors have been studied insufficiently.

Aim: To conduct a comparative study of plasminogen regulation in optic nerve sheath meningiomas, glioblastomas, and brain metastases of breast cancer, as well as in perifocal tissues surrounding the tumors.

Material And Methods: Tumors and perifocal areas of 19 breast cancer (BC) metastases, 24 glioblastomas, and 13 meningiomas without perifocal edema were investigated by ELISA in 56 patients aged 35-72 years. Read More

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http://dx.doi.org/10.17116/neiro201781222-27DOI Listing
April 2018
12 Reads

Visual Outcomes and Local Control After Fractionated Stereotactic Radiotherapy for Optic Nerve Sheath Meningioma.

Ophthalmic Plast Reconstr Surg 2018 May/Jun;34(3):217-221

British Columbia Cancer Agency (BCCA).

Purpose: To review the outcomes of patients with optic nerve sheath meningiomas (ONSM) treated with fractionated stereotactic radiotherapy.

Methods: Patient characteristics, treatment, and outcomes were analyzed for all patients with primary and secondary ONSM treated from 2001 to 2012. Clinically significant visual acuity change was defined as a 2-line change on the Snellen eye chart from pre-fractionated stereotactic radiotherapy. Read More

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http://dx.doi.org/10.1097/IOP.0000000000000914DOI Listing
July 2018
17 Reads

Surgical Resection of an Optic Nerve Sheath Meningioma: Relevance of Endoscopic Endonasal Approaches to the Optic Canal.

J Neurol Surg Rep 2017 Apr;78(2):e81-e85

Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States.

Optic nerve sheath meningiomas (ONSMs) account for less than 2% of meningiomas and 1.7% of orbital tumors. Although rare, the management of these tumors is important as unilateral blindness often results in untreated cases. Read More

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http://dx.doi.org/10.1055/s-0037-1600897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391263PMC
April 2017
20 Reads

Update on the application of optic nerve sheath fenestration.

Restor Neurol Neurosci 2017 ;35(3):275-286

Sichuan Provincial Key Laboratory for Disease Gene Study, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China.

Background: With the ongoing development of surgical procedures and instruments, the safety of optic nerve sheath fenestration (ONSF) has been improved.

Objective: Through the past three decades, progress has been made in preventing visual loss from chronic optic nerve swelling in idiopathic intracranial hypertension (IIH), secondary intracranial hypertension and local optic nerve diseases. We now review the updated application of ONSF in those diseases. Read More

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http://dx.doi.org/10.3233/RNN-170693DOI Listing
March 2018
5 Reads

Somatostatin Receptor SPECT/CT using Tc Labeled HYNIC-TOC Aids in Diagnosis of Primary Optic Nerve Sheath Meningioma.

Indian J Nucl Med 2017 Jan-Mar;32(1):63-65

Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.

Primary optic nerve sheath meningiomas (ONSM) are rare, benign and slow growing tumor involving the intra-orbital/intra-canalicular segment of the optic nerve. Untreated, they can potentially lead to visual deterioration. Magnetic resonance (MR) is the gold standard imaging modality for diagnosing the entity. Read More

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http://dx.doi.org/10.4103/0972-3919.198487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317077PMC
March 2017
8 Reads

Diagnosis of optic nerve sheath meningioma during optic nerve sheath decompression.

Orbit 2017 Feb 3;36(1):35-38. Epub 2017 Feb 3.

a Department of Ophthalmology , SUNY Upstate Medical University , Syracuse , New York , USA.

Optic nerve sheath meningioma (ONSM) is typically diagnosed based on clinical suspicion and imaging characteristics and is most often treated with radiation. Historically, biopsy, optic nerve sheath decompression, and debulking surgeries have been avoided for fear of optic nerve vascular disruption and tumor spread into the orbit. This is a case of a 48-year-old man who presented with unilateral optic disc edema, declining visual acuity, and a visual field defect. Read More

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https://www.tandfonline.com/doi/full/10.1080/01676830.2017.1
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http://dx.doi.org/10.1080/01676830.2017.1279648DOI Listing
February 2017
6 Reads

Waiting to deliver a final diagnosis.

Surv Ophthalmol 2017 Jul - Aug;62(4):583-586. Epub 2017 Jan 25.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.

We report a patient with left eye positional transient visual obscurations, diplopia, a left afferent pupillary defect, and optic disk edema-all occurring during pregnancy. Noncontrast magnetic resonance imaging revealed an orbital mass encasing the optic nerve and extending through the superior orbital fissure into the cavernous sinus. An magnetic resonance imaging with gadolinium after parturition and strongly positive somatostatin receptor scintigraphy suggested the diagnosis of meningioma. Read More

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http://dx.doi.org/10.1016/j.survophthal.2017.01.006DOI Listing
September 2017
6 Reads

Orbital melanoma with calcification: A diagnostic dilemma.

Indian J Ophthalmol 2016 Dec;64(12):932-934

Department of Pathology, Aravind Eye Hospitals and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India.

Primary orbital melanoma is rare and has varied initial presentation. A 28-year-old female presented with proptosis and decreased vision in the left eye. Computed tomography scan showed an orbital mass with contrast enhancement and calcification around the optic nerve leading to a diagnosis of meningioma. Read More

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http://dx.doi.org/10.4103/0301-4738.198849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322711PMC
December 2016
5 Reads

A Retrospective Analysis of Vision-Impairing Tumors Among 467 Patients with Neurofibromatosis Type 2.

World Neurosurg 2017 Jan 21;97:557-564. Epub 2016 Oct 21.

Department of Neurosurgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China. Electronic address:

Background: Vision is important for patients with hearing loss caused by neurofibromatosis type 2 (NF2). Tumors adjacent to the anterior visual pathway can potentially impair the vision. Only a few case reports and small-series studies have been reported. Read More

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http://dx.doi.org/10.1016/j.wneu.2016.10.080DOI Listing
January 2017
9 Reads

Total recovery of optic nerve sheath meningioma.

BMJ Case Rep 2016 Oct 21;2016. Epub 2016 Oct 21.

Centre Hospitalier Universitaire de Rennes, Rennes, Bretagne, France.

We reported the case of a 43-year-old woman with a rapid progressive visual loss. The diagnosis of primary optic nerve sheath meningioma was made thanks to atypia evolution, clinical and radiological findings. The patient was treated with an intensity-modulated radiotherapy of 50. Read More

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http://dx.doi.org/10.1136/bcr-2016-215532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093749PMC
October 2016
8 Reads

Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma.

Int J Ophthalmol 2016 18;9(9):1315-9. Epub 2016 Sep 18.

Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.

Aim: To investigate clinical features of optic nerve sheath meningioma (ONSM) that was misdiagnosed, and to find methods to reduce the misdiagnoses.

Methods: Retrospective series study. Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan. Read More

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http://dx.doi.org/10.18240/ijo.2016.09.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028668PMC
September 2016
8 Reads

Results with Expanded Endonasal Resection of Skull Base Meningiomas Technical Nuances and Approach Selection Based on an Early Experience.

Turk Neurosurg 2016 ;26(5):662-70

University Hospital of Wales, Department of Neurosurgery, Cardiff, United Kingdom.

Aim: Reconstruction technique advances have created renewed enthusiasm for the expanded endonasal approach (EEA). However, as with any new technique, early experiences inevitably lead to more selective use of these techniques. We reviewed our experience of the expanded endonasal endoscopic approach for skull base meningiomas and place it in context of the literature. Read More

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http://www.turkishneurosurgery.org.tr/pdf/JTNEPUB_16105_onli
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http://www.turkishneurosurgery.org.tr/summary_en_doi.php3?do
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http://dx.doi.org/10.5137/1019-5149.JTN.16105-15.3DOI Listing
April 2017
18 Reads

An unusual radiological presentation of optic nerve sheath meningioma.

Saudi J Ophthalmol 2016 Apr-Jun;30(2):137-9. Epub 2016 Feb 13.

Sydney Eye Hospital, Australia; Concord Repatriation General Hospital, Australia.

Our report describes an unusual radiological presentation of optic nerve sheath meningioma. The classic radiological appearance of optic nerve thickening with enhancement and calcification within the tumor was not seen; instead, an elongating gadolinium enhancing band-like area adjacent to the superomedial aspect of the left optic nerve sheath was identified. The diagnosis was confirmed on histopathology. Read More

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http://dx.doi.org/10.1016/j.sjopt.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908049PMC
June 2016
11 Reads

Cystic change in primary paediatric optic nerve sheath meningioma.

Orbit 2016 Aug 16;35(4):236-8. Epub 2016 Jun 16.

a South Australian Institute of Ophthalmology and Discipline of Ophthalmology and Visual Sciences , University of Adelaide , Adelaide , South Australia , Australia.

Primary optic nerve sheath meningiomas (PONSM) are rare in children. Cystic meningiomas are an uncommon subgroup of meningiomas. We report a case of paediatric PONSM managed using observation alone that underwent cystic change and radiological regression. Read More

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http://dx.doi.org/10.1080/01676830.2016.1176212DOI Listing
August 2016
13 Reads

Optic nerve sheath meningioma detected by single- photon emission computed tomography/computed tomography somatostatin receptor scintigraphy: a case report.

J Med Case Rep 2016 Apr 22;10(1):96. Epub 2016 Apr 22.

Service de Biophysique et Médecine Nucléaire, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, 1, avenue Molière, 67098, Strasbourg, Cedex 09, France.

Background: Optic nerve sheath meningiomas account for only 2% of orbital lesions and 42% of optic nerve tumors. Diagnosis remains difficult because histologic confirmation carries a high risk of visual loss. Therefore, a less invasive and specific diagnostic method for differentiating optic nerve sheath meningiomas from other optic nerve lesions is needed to overcome the limitations of computed tomography and magnetic resonance imaging, and make the best individualized treatment decision. Read More

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http://dx.doi.org/10.1186/s13256-016-0885-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841063PMC
April 2016
17 Reads

Optic Nerve Sheath Meningioma Masquerading as Optic Neuritis.

Case Rep Neurol Med 2016 19;2016:5419432. Epub 2016 Jan 19.

Neurology Clinic, Dasman Diabetes Institute, P.O. Box 1180, 15462 Dasman, Kuwait; Al-Bahar Ophthalmology Center, Ibn Sina Hospital, P.O. Box 25427, 13115 Safat, Kuwait.

Optic neuritis is a common presentation of demyelinating disorders such as multiple sclerosis. It typically presents with acute painful monocular vision loss, whereas chronic optic neuropathy can be caused by compressive lesions along the anterior visual pathway, genetic, toxic, or nutritional causes. We report an unusual presentation mimicking optic neuritis, which was subsequently diagnosed as optic nerve sheath meningioma (ONSM). Read More

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http://downloads.hindawi.com/journals/crinm/2016/5419432.pdf
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http://dx.doi.org/10.1155/2016/5419432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745933PMC
February 2016
3 Reads

[Pediatric optic nerve sheath meningioma with intraocular extension].

J Fr Ophtalmol 2016 Mar 2;39(3):e69-72. Epub 2016 Feb 2.

Service d'ophtalmologie, CHU d'Angers, 4, rue Larrey, 49100 Angers, France; Singapore National Eye Centre, 11, Third Hospital Avenue, 168751 Singapour, Singapour; Singapore Eye Research Institute, 11, Third Hospital Avenue, 168751 Singapour, Singapour; Duke-NUS, 8, College Road, 169857 Singapour, Singapour. Electronic address:

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http://dx.doi.org/10.1016/j.jfo.2015.10.003DOI Listing
March 2016
4 Reads

Aneurysms Encased in Meningiomas: A Case Report and Review of the Literature.

J Neurol Surg A Cent Eur Neurosurg 2017 Jan 25;78(1):99-102. Epub 2016 Jan 25.

Department of Neurosurgery, UK Köln, Köln, Germany.

The coexistence of aneurysms and meningiomas is rare, and encasement of an aneurysm within a meningioma even more so. We report a case of an optic nerve sheath meningioma encasing an aneurysm of the internal carotid artery and present a brief review of the literature. Read More

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http://dx.doi.org/10.1055/s-0035-1570001DOI Listing
January 2017
4 Reads

The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial.

Trials 2015 Nov 14;16:519. Epub 2015 Nov 14.

Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.

Background: Atypical meningiomas are an intermediate grade brain tumour with a recurrence rate of 39-58 %. It is not known whether early adjuvant radiotherapy reduces the risk of tumour recurrence and whether the potential side-effects are justified. An alternative management strategy is to perform active monitoring with magnetic resonance imaging (MRI) and to treat at recurrence. Read More

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http://dx.doi.org/10.1186/s13063-015-1040-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650615PMC
November 2015
20 Reads

Optic Nerve Sheath Melanoma Presenting as a Central Retinal Vein Occlusion.

J Neuroophthalmol 2016 Mar;36(1):70-2

Department of Ophthalmology (AB, PS, NB), Pathology (JED), and School of Medicine (NS), State University of New York at Stony Brook, Stony Brook, New York.

A 64-year-old woman, with a history of diabetes and melanoma, developed a central retinal vein occlusion (CRVO) in her left eye. On exam, she had severe disc edema with retinal nerve fiber layer thickening, and anterior deformation of the peripapillary retinal pigment epithelium (RPE)/Bruch membrane layer (ppRPE/BM) toward the vitreous on spectral domain optical coherence tomography (SD-OCT) suggesting an optic nerve sheath (ONS) meningioma. Magnetic resonance imaging findings and ONS biopsy later confirmed a metastatic melanoma. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000310DOI Listing
March 2016
10 Reads

Orbital tumours and tumour-like lesions: exploring the armamentarium of multiparametric imaging.

Insights Imaging 2016 Feb 31;7(1):43-68. Epub 2015 Oct 31.

Department of Radiology, Geneva University Hospital and University of Geneva, Rue, Gabrielle-Perret-Gentil 4, 1211, Geneva 14, Switzerland.

Although the orbit is a small anatomical space, the wide range of structures present within it are often the site of origin of various tumours and tumour-like conditions, both in adults and children. Cross-sectional imaging is mandatory for the detection, characterization, and mapping of these lesions. This review focuses on multiparametric imaging of orbital tumours. Read More

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http://dx.doi.org/10.1007/s13244-015-0443-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729705PMC
February 2016
8 Reads

Primary Extradural Ectopic Orbital Meningioma.

Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S99-S101

*Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York New York; and †Department of Ophthalmology, Weill Cornell Medical College, New York, New York, U.S.A.

The authors describe a rare case of a primary extradural ectopic meningioma occurring in a 9-year-old female. A review of the literature with respect to clinical presentation, radiographic findings, management, and outcome among similar cases is discussed. Common features that may assist with diagnosing this unusual tumor include absence of bone or optic nerve sheath involvement, presentation at a young age, occurrence in the medial orbit, and sinus asymmetry on radiographic imaging. Read More

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http://dx.doi.org/10.1097/IOP.0000000000000578DOI Listing
September 2017
11 Reads