22,434 results match your criteria Meningioma


Outcomes of decompressive surgery for cavernous sinus meningiomas: long-term follow-up in 50 patients.

J Neurosurg 2019 Feb 15:1-8. Epub 2019 Feb 15.

1Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah; and.

OBJECTIVECavernous sinus meningiomas are complex tumors that offer a perpetual challenge to skull base surgeons. The senior author has employed a management strategy for these lesions aimed at maximizing tumor control while minimizing neurological morbidity. This approach emphasizes combining "safe" tumor resection and direct decompression of the roof and lateral wall of the cavernous sinus as well as the optic nerve. Read More

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http://dx.doi.org/10.3171/2018.10.JNS181480DOI Listing
February 2019

Clinical characteristics of and treatment protocol for trapped temporal horn following resection of lateral ventricular trigone meningioma: a single-center experience.

J Neurosurg 2019 Feb 15:1-10. Epub 2019 Feb 15.

1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing; and.

OBJECTIVETrapped temporal horn (TTH) is a rare subtype of loculated hydrocephalus that is often managed surgically. The natural history of TTH is not well understood, and there are few data on the outcomes of conservative management of this condition. The aim of this study was to analyze the clinical features and outcomes of conservatively and surgically managed cases of TTH. Read More

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http://dx.doi.org/10.3171/2018.11.JNS182710DOI Listing
February 2019

Risk factors and control of seizures in 778 Chinese patients undergoing initial resection of supratentorial meningiomas.

Neurosurg Rev 2019 Feb 15. Epub 2019 Feb 15.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.

This retrospective study explored the risk factors for the occurrence of seizures in the pre- and postoperative period in patients undergoing supratentorial meningiomas surgery to investigate those who are likely to benefit from prophylactic antiepileptic drugs (AEDs). We reviewed the medical records of 778 supratentorial meningiomas patients who were operated at our institution between 2011 and 2012. A total of 100 (12. Read More

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http://dx.doi.org/10.1007/s10143-019-01085-5DOI Listing
February 2019

Pathology of the carotid space.

Insights Imaging 2019 Feb 15;10(1):21. Epub 2019 Feb 15.

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, P.O. Box 648, Rochester, NY, 14642, USA.

The complex anatomy of the carotid space within a small confined area is unique to the head and neck and allows for a vast array of pathology. This paper will review the anatomy of the carotid space from the skull base to the thorax, defining its borders at multiple levels, as well as its contents. The paper will also describe the myriad of mass lesions and vascular pathologies that may occur within the carotid space. Read More

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http://dx.doi.org/10.1186/s13244-019-0704-zDOI Listing
February 2019

Intraindividual comparison of selective intraarterial versus systemic intravenous 68Ga-DOTATATE PET/CT in patients with inoperable meningioma.

Nuklearmedizin 2019 Feb 15;58(1):23-27. Epub 2019 Feb 15.

Department of Diagnostic and Interventional Neuroradiology, RWTH University Hospital Aachen.

Aim: Here we describe the results of superselective intraarterial application of diagnostic Ga-68-DOTA0,Tyr3-octreotate (Ga-68-DOTATATE) in a series of patients with inoperable WHO grade II meningiomas which were no longer amenable to radiotherapy.

Methods: Four patients with inoperable WHO grade II meningioma underwent systemic venous infusion of Ga-68-DOTATATE followed by PET/CT. Ga-68-DOTATATE application was repeated intraarterially via transfemoral catheterization of vessels supplying the meningioma and another PET/CT was performed. Read More

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http://dx.doi.org/10.1055/a-0802-5039DOI Listing
February 2019

Retrosigmoid intradural suprajugular approach to jugular foramen tumors with intraforaminal extension: surgical series of 19 cases.

World Neurosurg 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurosurgery, Tokyo Metropolitan Police Hospital, #4-22-1, Nakano, Nakano-ku, Tokyo, 164-8541, Japan.

Objective: The intraforaminal component of jugular foramen tumors is difficult to access surgically, as it requires complex approaches for radical removal and leads to a high recurrence due to residual tumor. The retrosigmoid suprajugular approach, intradural drilling of the roof of the jugular foramen, has been recently proposed for removal of such intraforaminal component without sacrificing the sigmoid-jugular venous system or requiring additional approaches. This study presents our experience with this approach and introduces the utility of intraoperative continuous vagus nerve monitoring. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.223DOI Listing
February 2019

Efficacy and safety of Gamma knife radiosurgery for meningiomas in patients with neurofibromatosis Type 2: A long-term follow-up single center study.

World Neurosurg 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurosurgery & Gamma Knife Center, Zhejiang Provincial People's Hospital & People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China. Electronic address:

Objective: To explore the efficacy and safety of Gamma Knife Radiosurgery (GKRS) for meningiomas in neurofibromatosis Type 2 (NF2) patients .

Methods: A series of 35 consecutive patients with 99 meningiomas in our department were retrospectively included from Jan 2000 to Dec 2015. Clinical records, MR image and follow-up data were reviewed. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.211DOI Listing
February 2019

Application of indocyanine green fluorescence endoscopic system in transsphenoidal surgery for pituitary tumors.

Acta Neurochir (Wien) 2019 Feb 14. Epub 2019 Feb 14.

Department of Neurosurgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Background: For the precise removal of pituitary tumors, preserving the surrounding normal structures, we need real-time intraoperative information on tumor location, margins, and surrounding structures. The aim of this study was to evaluate the benefits of a new intraoperative real-time imaging modality using indocyanine green (ICG) fluorescence through an endoscopic system during transsphenoidal surgery (TSS) for pituitary tumors.

Methods: Between August 2013 and October 2014, 20 patients with pituitary and parasellar region tumors underwent TSS using the ICG fluorescence endoscopic system. Read More

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http://dx.doi.org/10.1007/s00701-018-03778-0DOI Listing
February 2019

Association of hormone replacement therapy with increased risk of meningioma in women: A hospital-based multicenter study with propensity score matching.

Asia Pac J Clin Oncol 2019 Feb 13. Epub 2019 Feb 13.

Centre of Systems Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Aim: There is no consensus regarding the association between hormone replacement therapy (HRT) and risk of meningioma so far. We conducted the first study among Chinese female patients to investigate the influence of HRT use on the risk of meningioma.

Methods: We retrospectively collected records of diagnosis of meningioma for women aged 50 years and above during 2011-2016 and dispense of HRT prior to meningioma diagnosis in three tertiary hospitals in China. Read More

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http://doi.wiley.com/10.1111/ajco.13138
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http://dx.doi.org/10.1111/ajco.13138DOI Listing
February 2019
1 Read

Preservation of Hearing and Facial Nerve Function with the Microsurgical Excision of Large Vestibular Schwannomas: Experience with the Retrosigmoid Approach.

Cureus 2018 Dec 4;10(12):e3684. Epub 2018 Dec 4.

Neurosurgery, Aga Khan University Hospital, Karachi, PAK.

Introduction Vestibular schwannomas (VS) are the most common benign neoplasms of a cerebellopontine angle (CPA), which arise from the Schwann cells of the vestibulocochlear nerve. Eighty percent of CPA tumors are VS followed by meningioma as the second common mass lesion in this critical potential space. Treatment options range from watchful waiting with serial imaging studies to radiosurgery or a microsurgical excision or a combination of surgery and radiation therapy. Read More

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http://dx.doi.org/10.7759/cureus.3684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367112PMC
December 2018

Yield of screening blood work and MRI of the brain and orbits in the work-up of unilateral chronic optic neuropathy.

Eye (Lond) 2019 Feb 13. Epub 2019 Feb 13.

Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, ON, Canada.

Background/objectives: No guidelines exist for the investigation of treatable causes of chronic optic neuropathy, including sarcoidosis, lupus, and syphilis. The purpose of this study was to determine the diagnostic yield of screening blood work (ACE (Angiotensin Converting Enzyme) for sarcoidosis, Antinuclear Antibodies (ANA) for lupus, CMIA (chemiluminescence microparticle enzyme immunoassay) for syphilis) and contrast-enhanced MRI brain and orbits in atypical unilateral chronic optic neuropathy.

Subjects/methods: Retrospective review from February 2012 to June 2018 at a neuro-ophthalmology practice. Read More

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http://dx.doi.org/10.1038/s41433-018-0326-6DOI Listing
February 2019

New-onset psychiatric symptoms following intracranial meningioma in a patient with schizophrenia: a case study.

Braz J Psychiatry 2019 Jan-Mar;41(1):91-92

Departamento de Psiquiatria, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

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http://dx.doi.org/10.1590/1516-4446-2018-0055DOI Listing
February 2018

The association between preoperative edema and postoperative cognitive functioning and health-related quality of life in WHO grade I meningioma patients.

Acta Neurochir (Wien) 2019 Feb 13. Epub 2019 Feb 13.

Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands.

Background: Studies on the associations between preoperative cerebral edema, cognitive functioning, and health-related quality of life (HRQOL) in WHO grade I meningioma patients are virtually lacking. We studied the association between preoperative cerebral edema on postoperative cognitive functioning and HRQOL 6 months postoperatively in WHO grade I meningioma patients.

Methods: Twenty-one consecutive WHO grade I meningioma patients, who underwent surgery, were matched individually for age, gender, and educational level to healthy controls. Read More

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http://dx.doi.org/10.1007/s00701-019-03819-2DOI Listing
February 2019

Cognitive outcomes in meningioma patients undergoing surgery: individual changes over time and predictors of late cognitive functioning.

Neuro Oncol 2019 Feb 7. Epub 2019 Feb 7.

Department of Cognitive Neuropsychology, Tilburg University, The Netherlands.

Background: Meningioma patients are known to face cognitive deficits before and after surgery. We examined individual changes in cognitive performance over time and identified preoperative predictors of cognitive functioning 12 months after surgery in a large sample of meningioma patients.

Methods: Patients underwent neuropsychological assessment (NPA) using CNS Vital Signs 1 day before (T0), and 3 (T3) and 12 (T12) months after surgery. Read More

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https://academic.oup.com/neuro-oncology/advance-article/doi/
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http://dx.doi.org/10.1093/neuonc/noz039DOI Listing
February 2019
2 Reads

Subcutaneous extension of parasagittal atypical meningioma through parietal foramen.

World Neurosurg 2019 Feb 8. Epub 2019 Feb 8.

Kasukabe Medical Center, 6-7-1 Chuo, Kasukabe, Saitama 344-8588, Japan.

Meningiomas extended to the scalp without any bony changes are rare. A 79-year-old man presented with a large subcutaneous mass in the midline parieto-occipital region and progressive right hemiparesis. The contrast-enhanced millimetric computed tomography scans of the head showed the intracranial parasagittal enhanced mass invading the superior sagittal sinus, and the subcutaneous mass without any bony destructive, osteoblastic or osteolytic changes. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.185DOI Listing
February 2019
1 Read

Coexistence of intracranial solitary fibrous tumor/hemangiopericytoma and right middle cerebral artery aneurysm.

J Surg Case Rep 2019 Jan 31;2019(1):rjz013. Epub 2019 Jan 31.

Department of Radiology, Section of Neuroradiology Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

Intracranial solitary fibrous tumors are rare mesenchymal neoplasms originating in the meninges and constitute a heterogeneous group of rare spindle cell tumors that include benign and malignant neoplasms of which hemangiopericytoma is nowadays considered a cellular phenotypic variant. From literatures, the incidence of coexistence of brain tumors and intracranial aneurysms is ~0.7-5. Read More

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http://dx.doi.org/10.1093/jscr/rjz013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354750PMC
January 2019
1 Read

Surgical Treatment of Meningiomas - Outcome Associated With Type of Resection, Recurrence, Karnofsky Performance Score, Mitotic Count.

Open Access Maced J Med Sci 2019 Jan 11;7(1):56-64. Epub 2019 Jan 11.

University Clinic of Neurology, Clinical Center Mother Theresa, Faculty of Medicine, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.

Background: Meningiomas are the type of central nervous system tumours, derived from the cells of the arachnoid membrane that are well constrained from surrounding tissues, mainly no infiltrating neoplasm with benign features. Meningiomas consist about 15-20% of all primary intracranial neoplasms.

Aim: The evaluation of the outcome of the operatively treated meningiomas in relation with the Karnofsky performance score, survival, recurrence, type of the surgical excision, histological type, mitotic count (MC), localisation and volume of the lesion. Read More

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http://dx.doi.org/10.3889/oamjms.2018.503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352459PMC
January 2019
1 Read

Cluster-Like Headache Secondary to Anamnesis of Sphenoid Ridge Meningioma: A Case Report and Literature Review.

Front Neurol 2019 25;10:23. Epub 2019 Jan 25.

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Cluster headache is generally considered to be a primary headache; secondary cluster-like headache is quite rare, while cluster-like headache secondary to meningioma is even rarer. Here, we describe an unusual case with cluster-like headache 2.5 years after sphenoid ridge meningioma surgery. Read More

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http://dx.doi.org/10.3389/fneur.2019.00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357285PMC
January 2019
1 Read

Cranial nerve outcomes after surgery for frontal skull base meningiomas: the eternal quest of the maximum-safe resection with the lowest morbidity.

World Neurosurg 2019 Feb 7. Epub 2019 Feb 7.

Department of Neurosurgery, Rheinische Friedrich-Wilhelms-University, Bonn, Germany.

Purpose: Maximal aggressive meningioma resection is suggested to provide for the best tumor control rates. However, radical surgery of meningiomas located at the frontal skull base may be accompanied by the impairment of adjacent cranial nerve function that negatively impacts patient quality of life. We therefore analyzed our institutional database with regard to new cranial nerve deficits as well as postoperative CSF-leakage depending on the extent of tumor resection. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.171DOI Listing
February 2019

Stereotactic-guided dilatable endoscopic port surgery for deep-seated brain tumors: technical report with comparative case series analysis.

World Neurosurg 2019 Feb 7. Epub 2019 Feb 7.

Lexington Brain and Spine, Columbia SC, USA. Electronic address:

Objective: Deep-seated brain tumors are often best treated with primary surgical excision. Traditional microsurgical techniques may cause retraction injury and extensive brain dissection. To mitigate this risk, stereotactic-guided tubular retractors were developed, but the risk of shear injury remains. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.175DOI Listing
February 2019
1 Read

Outcome and prognostic factors for atypical meningiomas after first recurrence.

J Clin Neurosci 2019 Feb 5. Epub 2019 Feb 5.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Tiantan Xili 6, Dongcheng District, Beijing 100050, PR China. Electronic address:

Atypical meningioma (AM) tends to be tumor with high rates of recurrence and mortality. In this retrospective study, 131 recurrent AM patients underwent AM surgery in Beijing Tiantan Hospital between January 2008 and December 2015. Of the 131 cases collected, 61 were male (46. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.01.032DOI Listing
February 2019
1 Read

Long term outcome and health related quality of life of elderly patients after meningioma surgery.

World Neurosurg 2019 Feb 5. Epub 2019 Feb 5.

Department of General Neurosurgery, Center for Neurosurgery, University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.

Objective: The incidence of meningiomas is increasing with age. As the median age for the diagnosis is 65 years, general health condition, co-morbidity and procedural risks are influencing the postoperative functional outcome. Aim of our study was to assess the long term impairments of health related quality of life (HRQOL) after meningioma resection in different age groups of elderly patients. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.158DOI Listing
February 2019

Risk of Developing Postoperative Deficits Based on Tumor Location after Surgical Resection of an Intracranial Meningioma.

J Neurol Surg B Skull Base 2019 Feb 17;80(1):59-66. Epub 2018 Jul 17.

Department of Neurosurgery, Mayo Clinic Florida, Jacksonville, Florida, United States.

 Meningiomas occur in various intracranial locations. Each location is associated with a unique set of surgical nuances and risk profiles. The incidence and risk factors that predispose patients to certain deficits based on tumor locations are unclear. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1667066
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http://dx.doi.org/10.1055/s-0038-1667066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365240PMC
February 2019
4 Reads

Surgical Outcomes, Complications, and Management Strategies for Foramen Magnum Meningiomas.

J Neurol Surg B Skull Base 2019 Feb 28;80(1):1-9. Epub 2018 May 28.

Department of Neurological Surgery, University of California, San Francisco, California, United States.

 Foramen magnum meningiomas (FMM) are complex lesions because of their proximity to the brain stem and posterior cerebrovasculature. The objective of this study is to report surgical outcomes and complications after resection of FMM.  A retrospective chart review was conducted on patients with FMM from 1998 to 2015. Read More

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http://dx.doi.org/10.1055/s-0038-1654702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365236PMC
February 2019
1 Read

Polymethylmethacrylate cranioplasty using low-cost customised 3D printed moulds for cranial defects - a single Centre experience: technical note.

Br J Neurosurg 2019 Feb 8:1-3. Epub 2019 Feb 8.

a Department of Neurosurgery, Clinical Hospital Centre Zagreb , Zagreb University School of Medicine , Zagreb , Croatia.

We report our experience with 3D customised cranioplasties for large cranial defects. They were made by casting bone cement in custom made moulds at the time of surgery. Between October 2015 and January 2018, 29 patients underwent the procedure; 25 underwent elective cranioplasties for large cranial defects and four were bone tumour resection and reconstruction cases. Read More

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http://dx.doi.org/10.1080/02688697.2019.1566514DOI Listing
February 2019

Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

Arq Bras Oftalmol 2019 Mar-Apr;82(2):155-157

Department of Neuro-radiology, Sheikh Khalifa Hospital, Abu Dhabi, UAE.

Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Read More

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http://www.gnresearch.org/doi/10.5935/0004-2749.20190032
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http://dx.doi.org/10.5935/0004-2749.20190032DOI Listing
August 2018
9 Reads

Dural masses: meningiomas and their mimics.

Insights Imaging 2019 Feb 6;10(1):11. Epub 2019 Feb 6.

Department of Neuroradiology, St Bartholomew's and the Royal London Hospitals, Whitechapel, London, E1 1BB, UK.

Meningiomas are the most common dural tumour. They are regularly being seen as an incidental finding on brain imaging and treated conservatively. However, there are many other dural masses which mimic their appearances, including primary neoplastic processes, metastases, granulomatous diseases and infection. Read More

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http://dx.doi.org/10.1186/s13244-019-0697-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365311PMC
February 2019
9 Reads

Oculomotor Nerve Palsy Associated with Duplication of Middle Cerebral Artery, Anterior Communicating Artery Aneurysm, and Parietal Meningioma.

Neuroophthalmology 2019 Feb 25;43(1):53-55. Epub 2018 Apr 25.

Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.

A 61-year-old male presents with diplopia of acute onset and progressive course. He has a history of previous intracranial haemorrhage that was surgically evacuated 7 years ago and was also associated with diplopia. Examination revealed left complete oculomotor nerve paralysis with a fixed and dilated left pupil. Read More

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http://dx.doi.org/10.1080/01658107.2018.1451902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351017PMC
February 2019
2 Reads

[Intracranial meningiomas].

Ugeskr Laeger 2019 Jan;181(4)

Meningiomas are the most frequent intracranial non-glial tumours. They are derived from arachnoid cap cells and are classified according to WHO histology-based classification. The epigenetic technique DNA methylation profiling has shown improved prognostic value in comparison to the current WHO classification. Read More

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January 2019

[Etiology and diagnostics of compressive optic neuropathies].

Vestn Oftalmol 2018 ;134(6):72-82

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Purpose: To determine the causes and study the clinical manifestations of compressive optic neuropathy (CON).

Material And Methods: The study included 24 male and 36 female patients with CON (in total 60 patients, 97 eyes). All patients underwent standard ophthalmic examination, as well as computer perimetry, magnetic resonance imaging (MRI), and/or computed tomography (CT) of the brain and orbit and magnetic resonance angiography (MRA). Read More

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http://dx.doi.org/10.17116/oftalma201813406172DOI Listing
January 2018

rCBV- and ADC-based Grading of Meningiomas With Glimpse Into Emerging Molecular Diagnostics.

Basic Clin Neurosci 2018 Nov-Dec;9(6):417-428. Epub 2018 Nov 1.

Department of Biotechnology & Molecular Medicine, Post Graduate Institute of Medical Sciences, Regional Cancer Centre, Sharma University of Health Sciences, Rohtak, Haryana, India.

Introduction: This study was conducted to grade meningiomas based on relative Cerebral Blood Volume (rCBV) and Apparent Diffusion Coefficient (ADC) to help surgeons plan the approach and extent of operation as well as decide on the need of any adjuvant radio/chemo therapy. The current and evolving genomic, proteomic, and spectroscopic technologies are also discussed which can supplement the current radiologic methods and procedures in grading meningiomas.

Methods: A total of 35 patients with meningioma prospectively underwent basic MR sequences (T1W, T2W, T2W/FLAIR) in axial, sagittal and coronal planes followed by Diffusion Weighted (DW) imaging having b value of 1000 (minimum ADC values used for analysis). Read More

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http://dx.doi.org/10.32598/bcn.9.6.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359681PMC
November 2018
1 Read

Reliability of clinical diagnosis of masses of the cerebellopontine angle: A retrospective multi-institutional study.

Am J Otolaryngol 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurotology, Michigan Ear Institute, St. John Providence Hospital and Medical Centers, 30055 Northwestern Highway, Suite #101, Farmington Hills, MI 48334, United States. Electronic address:

Objectives: To assess the accuracy of pre-operative diagnosis of masses of the cerebellopontine angle (CPA) when compared to surgical pathology.

Design: Retrospective chart review.

Participants: Patients who underwent surgery for CPA masses at two tertiary care institutions from 2007 to 2017. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.009DOI Listing
January 2019

Lessons learned in the evolution of endoscopic skull base surgery.

J Neurosurg 2019 Feb;130(2):337-346

2Otorhinolaryngology, NewYork-Presbyterian Hospital/Weill Cornell Medicine, New York; and.

OBJECTIVEEndoscopic skull base surgery (ESBS) is a relatively recent addition to the neurosurgical armamentarium. As with many new approaches, there has been significant controversy regarding its value compared with more traditional approaches to ventral skull base pathology. Although early enthusiasm for new approaches that appear less invasive is usually high, these new techniques require rigorous study to ensure that widespread implementation is in the best interest of patients. Read More

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http://dx.doi.org/10.3171/2018.10.JNS182154DOI Listing
February 2019
1 Read

Resection of Meningiomas Involving Major Dural Venous Sinuses: Classification, Technique and Long Term Results.

World Neurosurg 2019 Feb 1. Epub 2019 Feb 1.

Department of Neurosurgery, Harborview Medical Center, University of Washington, Seattle, Washington. Electronic address:

Objective: Management of meningiomas with major dural venous sinus involvement is challenging. We present our case series and perspective on reconstruction of the sinuses.

Methods: 55 patients underwent operations between 2005 and 2016 and the retrospective data were collected and analyzed. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.128DOI Listing
February 2019
2 Reads

Preservation of olfaction in anterior midline skull base meningiomas: a comprehensive approach.

Acta Neurochir (Wien) 2019 Feb 4. Epub 2019 Feb 4.

Department of Neurological Surgery, School of Medicine, University of Colorado, 12631 E. 17th Ave., C307, Aurora, CO, 80045, USA.

Background: Olfaction is an undervalued sense in neurosurgery. Attempted surgical resection of anterior cranial fossa meningiomas puts the olfactory pathway at risk. Preservation of olfaction may increase the postoperative quality of life. Read More

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http://dx.doi.org/10.1007/s00701-019-03821-8DOI Listing
February 2019

A Patient with a Benign and a Malignant Primary Pulmonary Meningioma: An Evaluation with 18F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Computed Tomography with Iodinated Contrast.

Indian J Nucl Med 2019 Jan-Mar;34(1):45-47

Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.

An 80-year-old male with a previous history of thymoma and kidney cancer underwent a F fluorodeoxyglucose (FDG) positron emission tomography (PET)/contrast-enhanced computed tomography (CT) scan: two pulmonary nodules were discovered, both characterized by an increased glucose uptake. Of them, only one showed mild contrast enhancement. Both nodules were surgically resected: the first nodule was a benign meningioma and the second one was a malignant meningioma. Read More

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http://dx.doi.org/10.4103/ijnm.IJNM_101_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352649PMC
February 2019
1 Read

The Incidence of Nonmalignant Diseases among Patients with Suspected Carcinoma of Unknown Primary Site.

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Japan.

Objective Few reports have analyzed the diagnostic process of carcinoma of unknown primary site (CUP) or have focused on the frequency of nonmalignant lesions among patients with suspected malignant diseases. The aim of this study was to investigate the incidence and characteristics of nonmalignant diseases that tend to be mistaken for malignant diseases. Patients We retrospectively analyzed the medical records of patients with suspected CUP who were referred to the National Cancer Center Hospital (Tokyo, Japan) between April 2007 and December 2014. Read More

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http://dx.doi.org/10.2169/internalmedicine.1118-18DOI Listing
February 2019
1 Read

Factors Associated With Meningioma Detected in a Population-Based Sample.

Mayo Clin Proc 2019 Feb;94(2):254-261

Department of Health Sciences Research, Mayo Clinic, Rochester, MN.

Objective: To determine the frequency of incidental meningioma and identify associated factors in a population-based sample of participants who systematically underwent brain imaging.

Patients And Methods: We searched the Mayo Clinic Study of Aging, a population-based sample of Olmsted County, Minnesota, residents who underwent longitudinal magnetic resonance imaging of the brain. Using a text search of radiologists' notes for 2402 individuals (median age, 75. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00256196183068
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http://dx.doi.org/10.1016/j.mayocp.2018.07.026DOI Listing
February 2019
5 Reads

The correlation between phosphorylated Histone H3 (PHH3) and p-STAT3 in Meningiomas.

Clin Neurol Neurosurg 2019 Jan 25;178:46-50. Epub 2019 Jan 25.

Neurosurgery Department, Bezmialem Vakif University, Fatih, Istanbul, Turkey.

Objective: To assess the correlation between PHH-3 and STAT-3 in grade I and grade II meningiomas.

Patients And Methods: Medical records were retrospectively reviewed for all cranial cases which diagnosed and underwent surgery at Bezmialem Vakif University Hospital between 2012 and 2017. All cranial grade I and grade II meningioma patients constituted the core sample for this study. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.01.016DOI Listing
January 2019

Intracranial stenting after tumor exeresis complicated by delayed kinking of the middle cerebral artery.

Acta Neurochir (Wien) 2019 Feb 2. Epub 2019 Feb 2.

Neuroradiology Unit, University Hospital of Padova, Padua, Italy.

During intracranial tumor resection, the delayed kinking of a major encased vessel has never been described in literature. We present a case which required urgent endovascular treatment performed through a stent positioning. A patient was hospitalized with symptomatic sphenoid meningioma in the left middle cranial fossa. Read More

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http://dx.doi.org/10.1007/s00701-019-03822-7DOI Listing
February 2019
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Analysis of MRI Volumetric Changes After Hypofractionated Stereotactic Radiation Therapy for Benign Intracranial Neoplasms.

Adv Radiat Oncol 2019 Jan-Mar;4(1):43-49. Epub 2018 Aug 23.

Department of Radiation Oncology, Mayo Clinic Hospital, Phoenix, Arizona.

Purpose: To quantitatively assess volumetric changes after hypofractionated stereotactic radiation therapy (HFSRT) in patients treated for vestibular schwannomas and meningiomas.

Methods And Materials: We retrospectively reviewed records of patients treated with HFSRT at our institution from 2002 to 2014. Patients received a median dose of 25 Gy in 5 fractions. Read More

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http://dx.doi.org/10.1016/j.adro.2018.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349623PMC

Extra-striatal ptake of Tc-TRODAT SPECT in a erebral eningioma: A Case Report.

Asia Ocean J Nucl Med Biol 2019 ;7(1):99-102

Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrast-enhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. Tc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. Read More

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http://dx.doi.org/10.22038/AOJNMB.2018.11933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352060PMC
January 2019

Low TGF-β3 expression predicts tumor malignancy in meningiomas.

World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China. Electronic address:

Objective: To clarify the expression characteristics and prognostic significance of TGF-β3 in cranial meningiomas.

Methods: We analyzed the expression of TGF-β3 at the mRNA level in 38 frozen meningioma samples. Clinical data collection, follow-up, correlations and survival analyses were performed. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.077DOI Listing
January 2019
2.417 Impact Factor

A Case of Primary Sellar Paraganglioma: Immunohistochemistry Resource and Review.

World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, 5841 S. Maryland Avenue, Chicago, IL. Electronic address:

Background: The differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Seldom is primary paraganglioma considered. Here we present a case of this unique pathology, review the relevant literature and compile a compendium of immunohistochemical characteristics for use as a resource. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.094DOI Listing
January 2019
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Perioperative olfactory dysfunction in patients with meningiomas of the anteromedial skull base.

Clin Anat 2019 Jan 31. Epub 2019 Jan 31.

Department of Neurosurgery, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg/Saar, Germany.

Objective: Olfactory dysfunction represents a main symptom in olfactory groove meningiomas (OGM). Besides this, olfactory function has been sparsely investigated in patients suffering from supratentorial meningiomas. Here, the authors explore pre- and postoperative variables associated with olfactory dysfunction in supratentorial meningioma patients. Read More

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http://doi.wiley.com/10.1002/ca.23346
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http://dx.doi.org/10.1002/ca.23346DOI Listing
January 2019
4 Reads

Phenytoin Toxicity During Neoadjuvant Concurrent Capecitabine and Radiation Therapy for Rectal Adenocarcinoma: Case Report of a Drug Interaction.

Cureus 2018 Nov 23;10(11):e3625. Epub 2018 Nov 23.

Radiation Oncology, The University of Ottawa, Ottawa, CAN.

Phenytoin toxicity occurs when serum levels exceed the therapeutic level, leading to symptoms such as nystagmus, slurred speech, and decreased coordination. This toxicity is sometimes caused by drug interactions. Interactions between phenytoin and capecitabine are not commonly documented. Read More

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http://dx.doi.org/10.7759/cureus.3625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347445PMC
November 2018
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[Clinicopathologic analysis of a series of intraventricular meningioma].

Zhonghua Bing Li Xue Za Zhi 2019 Feb;48(2):137-140

Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.02.012DOI Listing
February 2019

Trigeminal Meningioma in a Patient with Tardive Dyskinesia as Only Symptom.

Case Rep Neurol Med 2018 31;2018:6175165. Epub 2018 Dec 31.

Clinical County Emergency Hospital of Sibiu, Department of Neurology, Romania.

Most meningiomas are benign, encapsulated tumors (95% of the cases), generally undergoing a limited number of genetic aberrations. We present the case of a 74-year-old patient with no significant pathological history, who is admitted to the neurology ward for orofacial dyskinesias accompanied by hypoesthesia in the left hemiface, a symptomatology that had started insidiously about two months before and worsened progressively over the past 3 weeks. A cerebral MRI was performed which revealed a small mass with discrete T2 hyperintensity and T1 iso-signal compared to the gray matter located in the left pontine cistern, with a large, well-defined base at the level of the cerebral tentorium. Read More

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http://dx.doi.org/10.1155/2018/6175165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332992PMC
December 2018