7,386 results match your criteria Meniere Disease


New marsupialization technique in endolymphatic sac surgery.

Laryngoscope Investig Otolaryngol 2020 Jun 26;5(3):546-551. Epub 2020 May 26.

Skull Base Research Center The Five Senses Institute, Iran University of Medical Sciences Tehran Iran.

Objectives: The aim of the present study was to describe and evaluate the results of a new technique in endolymphatic sac decompression surgery.

Methods: Forty-three patients with intractable unilateral Meniere's disease were selected. Endolymphatic sac was identified after simple mastoidectomy, and its lateral layer was incised, using a sickle knife. Read More

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http://dx.doi.org/10.1002/lio2.403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314464PMC

Evidence of Large Vestibulo-Ocular Reflex Reduction in Patients With Menière Attacks.

Otol Neurotol 2020 Jun 24. Epub 2020 Jun 24.

Department of Neurology, Dr. Cesar Milstein Hospital, Buenos Aires, Argentina.

Objective: To examine the high frequency horizontal vestibular ocular-reflex (hVOR) during acute attacks of vertigo in Menière's disease (MD).

Study Design: Retrospective case series and literature review.

Setting: Tertiary academic medical center. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002746DOI Listing

What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis.

J Neurol 2020 Jun 25. Epub 2020 Jun 25.

Department of Otolaryngology, Tenth People's Hospital of Tongji University, Shanghai, 200065, China.

Objective: To compare the efficacy of gentamicin and steroids in patients with Meniere's disease (MD).

Methods: The study protocol was structured in accordance with the Population, Intervention, Comparison and Outcome (PICO) framework. We used "Endnote" (Thomson ResearchSoft; Stanford, Connecticut, the United States) to retrieve database documents. Read More

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http://dx.doi.org/10.1007/s00415-020-10011-5DOI Listing

Hearing Preservation in Patients Who Undergo Labyrinthectomy and Translabyrinthine Procedures: A Case Report and Systematic Review.

JAMA Otolaryngol Head Neck Surg 2020 Jun 25. Epub 2020 Jun 25.

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston.

Importance: Preservation of endolymphatic fluids, maintenance of a fluid-filled vestibule, and preservation of the cochlear nerve and its vasculature are believed to be necessary to retaining hearing after an inner-ear operation. However, some studies have reported no hearing loss despite the violation of the vestibule, questioning the importance of maintaining a fluid-filled vestibule in preserving hearing.

Objective: To report on the preservation of hearing after a complete labyrinthectomy for Meniere disease and after disruption of the vestibule. Read More

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http://dx.doi.org/10.1001/jamaoto.2020.1292DOI Listing

Endolymphatic hydrops mimicking obstructive Eustachian tube dysfunction: preliminary experience and literature review.

Eur Arch Otorhinolaryngol 2020 Jun 24. Epub 2020 Jun 24.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Frauenklinikstrasse 24, 8091, Zurich, Switzerland.

Purpose: Aural fullness is a common symptom of middle ear diseases, most importantly Eustachian tube dysfunction (ETD). Yet, aural fullness may also be caused by inner ear disorders, such as hydropic ear diseases. Here, we report our experience with endolymphatic hydrops (EH) mimicking ETD. Read More

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http://dx.doi.org/10.1007/s00405-020-06139-9DOI Listing

Using betahistine in the treatment of patients with Menière's disease: a meta-analysis with the current randomized-controlled evidence.

Acta Otolaryngol 2020 Jun 25:1-9. Epub 2020 Jun 25.

The Danish Health Authority, Copenhagen, Denmark.

Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist. The objective of this systematic review was to provide an overview and rate the certainty of the current evidence base regarding the use of betahistine to treat patients with Menière's disease. Read More

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http://dx.doi.org/10.1080/00016489.2020.1777326DOI Listing

Current status on researches of Meniere's disease: a review.

Acta Otolaryngol 2020 Jun 21:1-5. Epub 2020 Jun 21.

Ear Nose and Throat Patient Area, Trauma and Reparative Medicine Theme, Karolinska University Hospital, Stockholm, Sweden.

Meniere's disease (MD) is a complex and multifactorial inner ear disease. The etiology of MD is unclear. Significant progress had been made in diagnosis and treatment. Read More

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http://dx.doi.org/10.1080/00016489.2020.1776385DOI Listing

The pharmacological management of vertigo in Meniere disease.

Expert Opin Pharmacother 2020 Jun 15:1-11. Epub 2020 Jun 15.

Department of Otolaryngology, Instituto de Investigación Biosanitaria Ibs.GRANADA, Hospital Universitario Virgen de las Nieves, Universidad de Granada , Granada, Spain.

Introduction: The term Meniere disease (MD) gathers a set of rare diseases involving the inner ear characterized by episodic vertigo associated with fluctuating auditory symptoms. Five clinical subgroups of patients have been defined, including familial MD, autoimmune MD, and MD with migraine. The diagnosis is based on clinical criteria as no biomarker is available, but genetic factors have a significant contribution in familial and non-familial MD. Read More

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http://dx.doi.org/10.1080/14656566.2020.1775812DOI Listing

Dietary Restriction for The Treatment of Meniere's Disease.

Transl Med UniSa 2020 May 31;22:5-9. Epub 2020 May 31.

Department of Medicine and Surgery, University of Salerno, Salerno, Italy.

Meniere's disease (MD) is an idiopathic inner ear disorder characterized by spontaneous recurrent vertigo, fluctuating sensorineural hearing loss (SNHL), aural fullness and tinnitus. Endolymphatic hydrops (EH) of the inner ear is currently considered the pathophysiological mechanisms that underlies typical symptoms of MD. MD diagnosis is based on the criteria of the Baràny Society. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265917PMC

Removal of biofilm is essential for long-term ventilation tube retention.

World J Clin Cases 2020 May;8(9):1592-1599

Department of Otorhinolaryngology-Head & Neck Surgery, the Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China.

Background: Although long-term retention of a ventilation tube is required in many ear diseases, spontaneous removal of conventional ventilation tube is observed in patients within 3 to 12 mo. To address this issue, we aimed to determine a new method for long-term retention of the ventilation tube.

Aim: To explore the value of removing the biofilm for long-term retention of tympanostomy ventilation tubes. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i9.1592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211535PMC

The Use of the Internet and Social Media by Individuals with Ménière's Disease: An Exploratory Survey of Finnish Ménière Federation Members.

J Int Adv Otol 2020 Apr;16(1):13-17

University of Tartu School of Medicine, Tartu, Estonia.

Objectives: The present study explored the use of the Internet and social media by individuals with Ménière's disease (MD).

Materials And Methods: This study utilized a retrospective design and included the data of 465 individuals with MD from the Finnish Ménière Federation (FMF) database. Moreover, the participants included 346 females (i. Read More

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http://dx.doi.org/10.5152/iao.2020.7563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224418PMC

Computing Endolymph Hydrodynamics During Head Impulse Test on Normal and Hydropic Vestibular Labyrinth Models.

Front Neurol 2020 21;11:289. Epub 2020 Apr 21.

Vestibular Research Laboratory, School of Psychology, The University of Sydney, Sydney, NSW, Australia.

Build a biologic geometry based computational model to test the hypothesis that, in some circumstances, endolymphatic hydrops can mechanically cause enhanced eye velocity responses during clinical conditions of the head impulse test. Some recent clinical and experimental findings had suggested that enhanced eye velocity responses measured with the video head impulse test could not only be caused by recording artifacts or central disfunction but also could be directly caused by the mechanical effect of endolymphatic hydrops on horizontal semicircular canal receptor. Data from clinical video head impulse test was computed in three biologic-based geometry models governed by Navier-Stokes equations; six head impulses of incrementally increasing peak head velocity were computed in each one of the three different geometric models, depending on absence, canal or utricular hydrops. Read More

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http://dx.doi.org/10.3389/fneur.2020.00289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193182PMC

Therapeutic role of intravenous glycerol for Meniere's disease. Preliminary results.

Am J Otolaryngol 2020 Jul - Aug;41(4):102498. Epub 2020 Apr 21.

Department of Sense Organs, Sapienza University Rome, Rome, Italy; Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA. Electronic address:

Purpose: Osmotic diuretics such as glycerol are used for diagnostic purposes in patients with a suspect of Meniere's disease (MD). Scientific evidence in the animal model and in humans has shown that glycerol can induce a reduction in endolymphatic hydrops; however, its use for therapeutic purposes in MD has never been reported. The aim of this study was to evaluate the effectiveness on symptom control of intravenous glycerol in a sample of patients with definite unilateral MD not responsive to dietary restrictions. Read More

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http://dx.doi.org/10.1016/j.amjoto.2020.102498DOI Listing

Bidirectional analysis of the association between Ménière's disease and depression: Two longitudinal follow-up studies using a national sample cohort.

Clin Otolaryngol 2020 Apr 26. Epub 2020 Apr 26.

Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang, Korea.

Objective: This study aimed to delineate the causal relationship between Ménière's disease and depression.

Design: Two longitudinal follow-up studies.

Main Outcome Measures: The 2002-2013 Korean National Health Insurance Service-Health Screening Cohort was used. Read More

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http://dx.doi.org/10.1111/coa.13558DOI Listing

Depression in Ménière's disease: a systematic review and meta-analysis.

J Laryngol Otol 2020 Apr;134(4):293-301

Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, USA.

Background: Ménière's disease is a debilitating chronic peripheral vestibular disorder associated with psychiatric co-morbidities, notably depression.

Methods: Database searches were performed to identify studies that assessed depression in Ménière's disease. Metrics used to diagnose depression were extracted, along with the prevalence of depression in each study. Read More

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http://dx.doi.org/10.1017/S002221512000081XDOI Listing

Concerns of Patients With Ménière Disease in Ethiopia, India, and the United States.

JAMA Otolaryngol Head Neck Surg 2020 Apr 9. Epub 2020 Apr 9.

Department of Otolaryngology-Head and Neck Surgery, University of Illinois Hospitals, Chicago, Chicago.

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http://dx.doi.org/10.1001/jamaoto.2019.2663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146529PMC

Clinical Practice Guideline: Ménière's Disease Executive Summary.

Otolaryngol Head Neck Surg 2020 04;162(4):415-434

American Academy of Otolaryngology-Head and Neck Surgery, Alexandria, Virginia, USA.

Objective: Ménière's disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the episodes of vertigo. It also presents with fluctuating aural symptoms (hearing loss, tinnitus, or ear fullness) in the affected ear. The underlying etiology of MD is not completely clear, yet it has been associated with inner ear fluid volume increases, culminating in episodic ear symptoms (vertigo, fluctuating hearing loss, tinnitus, and aural fullness). Read More

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http://dx.doi.org/10.1177/0194599820909439DOI Listing

Plain Language Summary: Ménière's Disease.

Otolaryngol Head Neck Surg 2020 04;162(4):435-445

American Academy of Otolaryngology-Head and Neck Surgery Foundation, Alexandria, Virginia, USA.

This plain language summary explains Ménière's (pronounced men-yerz) disease (MD) to patients. The summary applies to patients aged 18 years and older with a suspected diagnosis of definite or probable MD. It is based on the 2020 "Clinical Practice Guideline: Ménière's Disease. Read More

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http://dx.doi.org/10.1177/0194599820909437DOI Listing

Clinical Practice Guideline: Ménière's Disease.

Otolaryngol Head Neck Surg 2020 04;162(2_suppl):S1-S55

American Academy of Otolaryngology-Head and Neck Surgery, Alexandria, Virginia, USA.

Objective: Ménière's disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the episodes of vertigo. It also presents with fluctuating aural symptoms (hearing loss, tinnitus, or ear fullness) in the affected ear. The underlying etiology of MD is not completely clear, yet it has been associated with inner ear fluid (endolymph) volume increases, culminating in episodic ear symptoms (vertigo, fluctuating hearing loss, tinnitus, and aural fullness). Read More

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http://dx.doi.org/10.1177/0194599820909438DOI Listing

MRI evaluation of the endolymphatic space in otosclerosis and correlation with clinical findings.

Diagn Interv Imaging 2020 Apr 3. Epub 2020 Apr 3.

Department of Neuroradiology, Lariboisière University Hospital, Assistance Publique-Hopitaux de Paris, 75010 Paris, France; Université de Paris, Diderot-Paris 7, 75010 Paris, France. Electronic address:

Purpose: The purpose of this study was to investigate the clinical features of ears with otosclerosis and their correlation with endolymphatic hydrops and blood-labyrinth barrier (BLB) impairment on 3T magnetic resonance imaging (MRI).

Materials And Methods: This was a single-center retrospective imaging study. Thirty-nine ears from 29 patients (17 men, 12 women; mean age 52±12 [SD] years; range 27-74 years) with non-operated otosclerosis were included. Read More

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http://dx.doi.org/10.1016/j.diii.2020.03.009DOI Listing

Menière's disease patients improve specific posturographic parameters following diagnostic intratympanic injection.

Am J Otolaryngol 2020 Jul - Aug;41(4):102468. Epub 2020 Mar 24.

Department of Neuroscience, Imaging e Clinical Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.

Purpose: Evaluation of specific computerized posturographic parameters in patients with Menière's disease (MD) following the intratympanic injection of gadolinium, a contrast agent, used in radiological diagnosing.

Materials And Methods: We have observed 12 adult patients with unilateral Menière's Disease subjected to inner ear magnetic resonance imaging (MRI) examination after intratympanic gadolinium injection (ITG). The diagnoses have been performed according to the guidelines of the American Academy of otolaryngology. Read More

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http://dx.doi.org/10.1016/j.amjoto.2020.102468DOI Listing

Magnetic resonance imaging of Ménière's disease: early clinical experience in a UK centre.

J Laryngol Otol 2020 Apr 3;134(4):302-310. Epub 2020 Apr 3.

Department of Radiology, Guy's and St Thomas' Hospital, London, UK.

Background: Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored.

Objective: To evaluate our centre's experience to date of hydrops magnetic resonance imaging in patients with episodic vertigo.

Methods: Magnetic resonance imaging was performed using a high-resolution three-dimensional fluid-attenuated inversion recovery sequence on a 3 Tesla scanner at 4 hours following double-dose gadolinium administration. Read More

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http://dx.doi.org/10.1017/S0022215120000626DOI Listing

Comparison of Enhancement of the Vestibular Perilymph between Variable and Constant Flip Angle-Delayed 3D-FLAIR Sequences in Menière Disease.

AJNR Am J Neuroradiol 2020 04 19;41(4):706-711. Epub 2020 Mar 19.

From the Departments of Neuroradiology (S.N., J.-P.G., A.G., E.H., M.E.), and

Background And Purpose: Endolymphatic hydrops in patients with Menière disease relies on delayed postcontrast 3D-FLAIR sequences. The purpose of this study was to compare the degree of perilymphatic enhancement and the detection rate of endolymphatic hydrops using constant and variable flip angles sequences.

Materials And Methods: This was a retrospective study performed in 16 patients with Menière disease who underwent 3T MR imaging 4 hours after gadolinium injection using two 3D-FLAIR sequences with a constant flip angle at 140° for the first and a heavily-T2 variable flip angle for the second. Read More

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http://dx.doi.org/10.3174/ajnr.A6483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144642PMC

Effect of electroacupuncture on arginine vasopressin-induced endolymphatic hydrops.

J Tradit Chin Med 2019 04;39(2):221-228

Department of Acupuncture and Moxibustion, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Objective: To investigate the influence of electroacupuncture (EA) on experimentally induced endolymphatic hydrops (EH) in guinea pigs, and elucidate the association between the dehydrating effect of EA and changes in stria vascularis ultrastructure and expression of vasopressin type 2 receptor (V2R), cyclic adenosine monophosphate (cAMP), and aquaporin 2 (AQP2) in the endolymphatic sac (ES).

Methods: The EH model was established by intraperitoneal injection of arginine vasopressin (AVP). As a treatment, EA was delivered to Baihui (GV 20) and Tinggong (SI 19) acupoints, once daily for 10 consecutive days. Read More

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Vestibular drop attacks in Ménière's disease and its association with migraine.

Eur Arch Otorhinolaryngol 2020 Jul 17;277(7):1907-1916. Epub 2020 Mar 17.

Department of Speech and Hearing Sciences, Lamar University, Beaumont, TX, USA.

Purpose: We explored the association of vestibular drop attacks (VDA) with or without migraine in patients with Ménière's disease (MD) and compared with patients classified as vestibular migraine (VM).

Method: The study involved a cross-sectional survey design. Data were collected from 401 members of Finnish Ménière Federation who experienced VDA. Read More

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http://dx.doi.org/10.1007/s00405-020-05890-3DOI Listing

Contrast-Enhanced MRI Combined With the Glycerol Test Reveals the Heterogeneous Dynamics of Endolymphatic Hydrops in Patients With Menière's Disease.

J Magn Reson Imaging 2020 Mar 11. Epub 2020 Mar 11.

Department of Otorhinolaryngology - Head & Neck Surgery, The Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.

Background: The sensitivity of endolymphatic hydrops (EH) to the glycerol test varies in patients with Menière's disease (MD).

Purpose: To explore the features of EH and its glycerol-induced dynamics in MD.

Study Type: Case-control study. Read More

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http://dx.doi.org/10.1002/jmri.27127DOI Listing

Wideband Tympanometry in Meniere's Disease.

Indian J Otolaryngol Head Neck Surg 2020 Mar 25;72(1):8-13. Epub 2019 Jul 25.

Department of Otorhinolaryngology, Faculty of Medicine, Recep Tayyip Erdogan University, Sehitler Street, No:74, Rize, Turkey.

The aim of our study was to obtain wideband tympanometry (WBT) findings in Meniere's disease (MD). It also aimed to evaluate whether the data obtained have diagnostic significance. 21 patients who were followed-up for unilateral Meniere's Disease were evaluated. Read More

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http://dx.doi.org/10.1007/s12070-019-01709-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040131PMC

Teaching Video NeuroImages: Intralabyrinthine schwannoma masquerading as Ménière disease.

Neurology 2020 Mar 4;94(11):e1227-e1228. Epub 2020 Mar 4.

From the Department of Neurology (S.-U.L.), Korea University Medical Center, Seoul; and Research Administration Team (H.-J.K.), Dizziness Center, Clinical Neuroscience Center (J.-Y.C., J.-S.K.), and Departments of Neurology (J.-Y.C., J.-S.K.), Otolaryngology-Head and Neck Surgery (J.-J.S.), and Radiology (B.-S.C.), Seoul National University Bundang Hospital, and Department of Neurology, Seoul National University College of Medicine (S.-U.L., J.-Y.C., J.-S.K.), Seongnam, South Korea.

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http://dx.doi.org/10.1212/WNL.0000000000009095DOI Listing

[Diagnosis and outcome analysis of diseases characterized by recurrent low-frequency sensorineural deafness].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Feb;34(2):106-112

Department of Otolaryngology Head and Neck Surgery,Chinese PLA Institute of Otolaryngology,National Clinical Research Center for Otolaryngologic Diseases,Key Lab of Hearing Impairment Science of Ministry of Education,Key Lab of Hearing Impairment Prevention and Treatment of Beijing,Chinese PLA General Hospital,Beijing,100853,China.

The aim of this study was to explore the clinical features, hearing prognosis and differential diagnosis of recurrent low frequency sensorineural hearing loss (RLFD) . The clinical characteristics, clinical manifestations, audiological examination and auxiliary examination of RLFD patients were retrospectively analyzed. We summarized clinical features, draw the pure tone audiometry curves, and analyze the diagnosis of RLFD. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2020.02.003DOI Listing
February 2020

[A review of endolymphatic sac-related surgeries and their possible mechanisms].

Authors:
B H He J Yang

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Jan;34(1):91-95

Endolymphatic sac-related surgeries are a series of effective procedures to treat patients with Ménière's disease. However, there is controversy since they were proposed in 1927. Although most studies have shown the effectiveness of endolymphatic decompression and endolymphatic shunting, the mechanisms of them are still unclear. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2020.01.023DOI Listing
January 2020

The Correlation Between Endolymphatic Hydrops and Clinical Features of Meniere Disease.

Laryngoscope 2020 Feb 21. Epub 2020 Feb 21.

Department of Radiology, First Hospital of China Medical University, Shenyang, People's Republic of China.

Objectives: The purpose of this study was to investigate the grades of endolymphatic hydrops determined by gadolinium-contrast magnetic resonance (MR) and correlation to the clinical features in patients with Meniere disease.

Study Design: Prospective study.

Methods: A total of 24 patients suffering from unilateral Meniere disease with either definite or probable clinical diagnosis were included. Read More

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http://dx.doi.org/10.1002/lary.28576DOI Listing
February 2020

MRI detection of endolymphatic hydrops in Meniere's disease in 8 minutes using MIIRMR and a 20-channel coil after targeted gadolinium delivery.

World J Otorhinolaryngol Head Neck Surg 2019 Dec 3;5(4):180-187. Epub 2020 Jan 3.

Department of Radiology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Background: Endolymphatic hydrops (EH) become visible in vertigo patients, particularly in those with Meniere's disease (MD), in vivo using gadolinium-enhanced MRI. However, the image quality is not satisfying after intravenous injection of gadolinium chelate (GdC), and occasional failure in GdC uptake has been noticed after traditional intratympanic injection. In the present report, targeted delivery of GdC and using a cost-effective MRI system to obtain high quality images of EH in only 8 min will be introduced. Read More

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http://dx.doi.org/10.1016/j.wjorl.2019.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015851PMC
December 2019

Authors' response to the letter on the article: "International consensus (ICON) on treatment of Ménière's disease".

Eur Ann Otorhinolaryngol Head Neck Dis 2020 05 10;137(3):239. Epub 2020 Feb 10.

Department of otolaryngology, Skull Base Surgery, CHU de Bordeaux, université de Bordeaux, 33000 Bordeaux, France.

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http://dx.doi.org/10.1016/j.anorl.2020.01.019DOI Listing

PET Visualized Stimulation of the Vestibular Organ in Menière's Disease.

Front Neurol 2020 28;11:11. Epub 2020 Jan 28.

Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

The cortical metabolic activity in patients with Menière's disease has not been investigated. The aim of this study was to investigate the F-FDG cerebral uptake in Menière's patients compared to healthy controls. Eight patients with right-sided Menière's disease and fourteen healthy controls underwent a video head impulse test (vHIT), test of utricular function with ocular vestibular evoked myogenic potentials (oVEMP) and three F-FDG-based PET examinations of the brain. Read More

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http://dx.doi.org/10.3389/fneur.2020.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997538PMC
January 2020

Rare Variants of Putative Candidate Genes Associated With Sporadic Meniere's Disease in East Asian Population.

Front Neurol 2019 22;10:1424. Epub 2020 Jan 22.

Department of Neurology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan, South Korea.

The cause of Meniere's disease (MD) is unclear but likely involves genetic and environmental factors. The aim of this study was to investigate the genetic basis underlying MD by screening putative candidate genes for MD. Sixty-eight patients who met the diagnostic criteria for MD of the Barany Society were included. Read More

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http://dx.doi.org/10.3389/fneur.2019.01424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987317PMC
January 2020

Value of Endolymphatic Hydrops and Perilymph Signal Intensity in Suspected Ménière Disease.

AJNR Am J Neuroradiol 2020 03 6;41(3):529-534. Epub 2020 Feb 6.

From the Departments of Radiology (J.M.v.S., L.M.H.d.P., S.H.).

Background And Purpose: Ménière disease is characterized by endolymphatic hydrops, whereas perilymphatic enhancement on MR imaging has been suggested to be of additional value in diagnosing Ménière disease. This study evaluates the presence of endolymphatic hydrops and perilymphatic enhancement in patients with Ménière disease and with other vertigo-associated inner ear pathology.

Materials And Methods: A 3D-FLAIR sequence 4 hours after intravenous gadolinium injection was performed to visualize the endolymph and perilymph in 220 patients suspected of having Ménière disease. Read More

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http://dx.doi.org/10.3174/ajnr.A6410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077918PMC

Analyze causes and results of VNG examinations in patients with vertigo and balance disorders in the private ENT practice.

Otolaryngol Pol 2019 Sep;74(2):23-30

Klinika Otolaryngologii, Onkologii Laryngologicznej, Audiologii i Foniatrii, II Katedry Otolaryngologii Uniwersytetu Medycznego w Łodzi.

Introduction: The aim of the study was to attempt to analyze the most common causes leading to dizziness, vertigo and balance disorders according to gender and age.

Material And Methods: Analysis of medical records and evaluation of VNG tests were performed on 608 patients of the private ENT practice "VERTIGO" in Opole between 2011 and 2017, including 404 women and 204 men. The patients' age was in the range from 18 to 85 years, average age 49. Read More

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http://dx.doi.org/10.5604/01.3001.0013.4374DOI Listing
September 2019

Usefulness of Ultrasound-Computer-Craniocorpography in Unilateral Ménière's Disease.

Biomed Hub 2019 May-Aug;4(2):1-7. Epub 2019 May 13.

Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Background: Ménière's disease (MD) is composed of a set of fluctuating symptoms, whereby vertigo is the most unpleasant among them and often accompanied by deterioration of the balance system.

Objectives: The purpose of this study is to objectively assess the Romberg and Unterberger-Fukuda tests by ultrasound-computer-craniocorpography (US-COMP-CCG) in patients suffering from MD and to characterize the balance disorders in different frames of MD.

Methods: This is a case-control study where 51 patients with normal vestibular system and 42 patients suffering from definite MD were examined by US-COMP-CCG. Read More

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http://dx.doi.org/10.1159/000500398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985893PMC

A Critical Analysis of the Information Available Online for Ménière's Disease.

Otolaryngol Head Neck Surg 2020 Mar 28;162(3):329-336. Epub 2020 Jan 28.

Michigan Ear Institute, Farmington Hills, Michigan, USA.

Objective: Patients increasingly rely on online resources for medical information; however, the Internet is unregulated and prone to misinformation. This study analyzes the reliability, quality, and readability of websites for Ménière's disease.

Study Design: A Google search was performed using keywords . Read More

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http://dx.doi.org/10.1177/0194599819901150DOI Listing

[Effect of the stapedius and tensor tympani muscles tenotomy on the quality of life of patients suffering from Ménière's disease].

Orv Hetil 2020 Feb;161(5):177-182

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Szigony u 36., 1083.

Tenotomy of the tendon of the stapedius and tensor tympani (TT) muscles is a minimal-invasive surgical therapeutic procedure in Ménière's disease (MD). It has been assumed that the TT medializes the stapes into the oval window, resulting in changes in perilymphatic pressures of the inner ear. By cutting the tendons of both middle ear muscles, they affect the pressure dynamics by not augmenting this pressure even further. Read More

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http://dx.doi.org/10.1556/650.2020.31634DOI Listing
February 2020

Towards a new staging of Ménière's disease: a vestibular approach.

Acta Otorhinolaryngol Ital 2019 Dec;39(6):419-428

Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

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http://dx.doi.org/10.14639/0392-100X-2461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966777PMC
December 2019

Nutritional Mushroom Treatment in Meniere's Disease with : A Rationale for Therapeutic Intervention in Neuroinflammation and Antineurodegeneration.

Int J Mol Sci 2019 Dec 31;21(1). Epub 2019 Dec 31.

Department of Medical and Surgery Sciences, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.

Meniere's disease (MD) represents a clinical syndrome characterized by episodes of spontaneous vertigo, associated with fluctuating, low to medium frequencies sensorineural hearing loss (SNHL), tinnitus, and aural fullness affecting one or both ears. To date, the cause of MD remains substantially unknown, despite increasing evidence suggesting that oxidative stress and neuroinflammation may be central to the development of endolymphatic hydrops and consequent otholitic degeneration and displacement in the reuniting duct, thus originating the otolithic crisis from vestibular otolithic organs utricle or saccule. As a starting point to withstand pathological consequences, cellular pathways conferring protection against oxidative stress, such as vitagenes, are also induced, but at a level not sufficient to prevent full neuroprotection, which can be reinforced by exogenous nutritional approaches. Read More

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http://dx.doi.org/10.3390/ijms21010284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981469PMC
December 2019

A model of viscoelastoplasticity in the cochleo-saccular membranes.

Authors:
Daniel J Pender

Laryngoscope Investig Otolaryngol 2019 Dec 9;4(6):659-662. Epub 2019 Nov 9.

Department of Otolaryngology Columbia University New York New York U.S.A.

Introduction: Variations in the distensile behavior of the cochleo-saccular vestibular membranes may contribute to lesion evolution of endolymphatic hydrops in Meniere's disease. Such variation may be mediated through membrane viscoelastoplasticity. This feature may provide insight into the distensile process at work in these membranes. Read More

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http://dx.doi.org/10.1002/lio2.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929575PMC
December 2019

Endolymphatic volume in patients with meniere's disease and healthy controls: Three-dimensional analysis with magnetic resonance imaging.

Laryngoscope Investig Otolaryngol 2019 Dec 7;4(6):653-658. Epub 2019 Nov 7.

Department of Otolaryngology-Head and Neck Surgery Nara Medical University Kashihara Nara Japan.

Objective: Recently, 3-Tesla magnetic resonance imaging (MRI) with intravenous gadolinium injection has been used to reveal endolymphatic hydrops (EH). In the present study, we aimed to evaluate EH in patients with Meniere's disease (MD) objectively and quantitatively, and compared the endolymphatic space (ELS) in individuals with MD and healthy controls, to gain understanding of the characteristics of MD.

Methods: Eighty-two patients with unilateral MD (uMD), 16 patients with bilateral MD (bMD), and 47 healthy volunteers were enrolled. Read More

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http://dx.doi.org/10.1002/lio2.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929584PMC
December 2019

Increased urinary volumes in symptomatic Ménière's Disease.

BMC Res Notes 2019 Dec 26;12(1):826. Epub 2019 Dec 26.

Audiology Unit, Dept of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Via Pace 9, 20122, Milan, Italy.

Objective: The purpose of the research is to test the measurement of the total urinary volume, induced by the diuretic osmotic action of mannitol, in a group of symptomatic MD patients and in healthy controls.

Results: An altered excretory urinary volume after mannitol challenge was observed in symptomatic MD (874.3 ± 302. Read More

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http://dx.doi.org/10.1186/s13104-019-4870-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933934PMC
December 2019

Diagnostic assessment of patients with Meniere's disease through caloric testing and the video-head-impulse test.

Braz J Otorhinolaryngol 2019 Nov 22. Epub 2019 Nov 22.

Universidade Federal de São Paulo (UNIFESP-EPM), Escola Paulista de Medicina, Disciplina de Otologia e Otoneurologia, São Paulo, SP, Brazil.

Introduction: Meniere's disease is a labyrinth disease that usually presents with episodes of spontaneous vertigo associated with sensorineural hearing loss, tinnitus and ipsi- and unilateral aural fullness in most cases. Vestibular function tests, video-head-impulse test and the caloric test, are not specific for diagnosis of the disease, but may show alterations that help to evaluate the functional impairment.

Objective: To describe the results obtained at the caloric test and video-head-impulse test in patients with definite Meniere's disease and compare them between symptomatic, asymptomatic ears and those of the control group. Read More

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http://dx.doi.org/10.1016/j.bjorl.2019.10.008DOI Listing
November 2019

Hyaluronic acid in otology: Its uses, advantages and drawbacks - A review.

Am J Otolaryngol 2020 Mar - Apr;41(2):102375. Epub 2019 Dec 13.

American University of Beirut Medical Center, P.O. Box 11-0236, Department of Otolaryngology and Head and Neck Surgery, Riad El-Solh, Beirut 1107 2020, Lebanon.

Objectives: Review of the literature for studies involving the use of hyaluronic acid (HA) in otology.

Methods: Pubmed and OvidMedline were searched using a combination of the following words in different variations: hyaluronic acid, hyaluronate, otolaryngology, otology, ear, tympanic membrane, perforation, tympanostomy, tympanoplasty, myringoplasty, packing, middle ear, cochlea, gene delivery, gene therapy, cochlear implant, hearing loss, meniere, vertigo, otitis and cholesteatoma.

Results: The papers relevant for this review were triaged based on abstracts and titles and were then categorized based on topic/disease entity/procedure. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.102375DOI Listing
December 2019

Ménière's disease clinical subtypes in a population from the USA.

J Laryngol Otol 2020 Jan 20;134(1):24-28. Epub 2019 Dec 20.

Department of Otolaryngology - Head and Neck Surgery, MedStar Georgetown University Hospital, Washington, DC, USA.

Objective: To ascertain the distribution of Ménière's disease phenotype subgroups in a US-based cohort, based on a recently introduced classification scheme utilising a Spanish and Portuguese cohort.

Methods: A retrospective, cross-sectional, single-institutional chart review was conducted. The electronic medical records of Ménière's disease patients were identified using International Classification of Diseases codes at a tertiary referral centre and reviewed to extract subgroup-defining features. Read More

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http://dx.doi.org/10.1017/S002221511900255XDOI Listing
January 2020

Menière's Disease and Caloric Stimulation: Some News from an Old Test.

J Int Adv Otol 2019 Dec;15(3):442-446

Department of Medicine and Surgery, Pisa University Hospital, Pisa University Hospital, Pisa, Italy.

Objectives: The aim of the present study was to improve the instrumental diagnosis of assessing Menière's disease (MD) if the frequency and slow-phase velocity (SPV) of the thermally induced nystagmus analyzed through the caloric vestibular test (CVT) showed different alterations in relationship with an increasing severity of the cochlear involvement.

Materials And Methods: The study retrospectively analyzed the CVT results of 72 patients affected by unilateral "definite MD" according to the 2015 Barany Society Diagnostic Criteria and treated only conservatively.

Results: There were 7 (9. Read More

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http://dx.doi.org/10.5152/iao.2019.7430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937176PMC
December 2019