7,160 results match your criteria Meniere Disease


Stability of Endolymphatic Hydrops in Ménière Disease Shown by 3-Tesla Magnetic Resonance Imaging During and After Vertigo Attacks.

JAMA Otolaryngol Head Neck Surg 2019 Apr 18. Epub 2019 Apr 18.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

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http://dx.doi.org/10.1001/jamaoto.2019.0435DOI Listing

Positive pressure therapy for Ménière’s disease.

Medwave 2019 Apr 8;19(3):e7610. Epub 2019 Apr 8.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Otorrinolaringología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: Ménière's disease is a disorder of the inner ear characterized by episodes of spontaneous vertigo, fluctuating hearing loss and tinnitus. Positive pressure therapy has been used to reduce the intensity and frequency of episodes, but it is not clear whether it is actually effective.

Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More

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http://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/761
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http://dx.doi.org/10.5867/medwave.2019.03.7609DOI Listing
April 2019
1 Read

Therapeutic strategies in the treatment of Menière's disease: the Italian experience.

Eur Arch Otorhinolaryngol 2019 Apr 11. Epub 2019 Apr 11.

UOSD "Vestibologia E Otorinolaringoiatria" Presidio Ospedaliero "Giovanni Paolo II", Policoro, Italy.

Purpose: Ménière's disease (MD) is an inner ear disorder of unknown etiology, whose pathological substrate is the endolymphatic hydrops. Different treatments have been proposed; however, evidence of their effectiveness is lacking. The aim of this study was to evaluate by a questionnaire which medical and surgical treatments are used in Italy for the treatment of MD and to compare them with those proposed in other countries. Read More

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http://dx.doi.org/10.1007/s00405-019-05423-7DOI Listing
April 2019
2 Reads

Cervical vestibular evoked myogenic potentials and video head impulse test in Ménière disease.

Braz J Otorhinolaryngol 2019 Mar 16. Epub 2019 Mar 16.

Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), Disciplina de Otologia e Otoneurologia, São Paulo, SP, Brazil.

Introduction: Ménière's disease is among the most frequent causes of vestibular disorders. Although it is a clinical diagnosis, a better understanding of the pathophysiology and clinical course of the disease through tests would allow improvement in the prognosis and more effective treatments.

Objectives: To describe the results of the cervical vestibular evoked myogenic and video-head impulse test in patients with a defined diagnosis of Ménière's disease and to correlate them with disease duration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18088694183062
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http://dx.doi.org/10.1016/j.bjorl.2019.02.002DOI Listing
March 2019
1 Read

Vestibular migraine treatment and prevention.

Authors:
A Lapira

HNO 2019 Apr 8. Epub 2019 Apr 8.

St James & Capua Hospitals, George Borg Olivier St, SLM 1807, Sliema, Malta.

Vestibular migraine probably represents the second most common cause of vertigo after benign positional vertigo, by far exceeding Ménière disease. There are still relatively few published reports on vestibular migraine management, despite its enormous importance in daily practice. In 2003 the first clinical definition of vestibular migraine was proposed. Read More

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http://link.springer.com/10.1007/s00106-019-0661-3
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http://dx.doi.org/10.1007/s00106-019-0661-3DOI Listing
April 2019
6 Reads

Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear.

Int Arch Otorhinolaryngol 2019 Apr 15;23(2):218-220. Epub 2019 Feb 15.

Department of Otolaryngology, Hospital Albert Einstein, São Paulo, SP, Brazil.

 Menière's disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Read More

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http://dx.doi.org/10.1055/s-0038-1673698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449135PMC

A Nationwide, Population-based Cohort Study on Potential Autoimmune Association of Ménière Disease to Atopy and Vitiligo.

Sci Rep 2019 Mar 13;9(1):4406. Epub 2019 Mar 13.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Konyang University, Daejeon, Republic of Korea.

Ménière disease (MD), an idiopathic disorder of sensorineural hearing loss and vertigo, shares many similarities with two common skin conditions, atopic dermatitis (AD) and vitiligo. Recent studies have suggested that MD may be related to or triggered by autoimmune conditions, notably Hashimoto thyroiditis and alopecia areata. These evidences led to the authors contemplating the possibility of immunological bridge between MD and the two skin conditions. Read More

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http://dx.doi.org/10.1038/s41598-019-40658-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416401PMC
March 2019
1 Read

Comparison of acute vertigo diagnosis and treatment practices between otolaryngologists and non-otolaryngologists: A multicenter scenario-based survey.

PLoS One 2019 7;14(3):e0213196. Epub 2019 Mar 7.

Division of General Internal Medicine, St. Luke's International Hospital, Tokyo Japan.

Acute vertigo is a common problem in emergency departments. However, clinical strategies of acute vertigo care vary among care providers. The aim of the study was to investigate differences in diagnosis [Dix-Hallpike test, the head impulse, nystagmus, and the test of skew (HINTS) procedure, and imaging modalities] and treatment (pharmacological treatments and the Epley maneuver) by otolaryngologists and non-otolaryngologists in emergency medicine settings. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213196PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405109PMC
March 2019
7 Reads

The pattern of hearing outcome following surgery of the semicircular canals.

Laryngoscope Investig Otolaryngol 2019 Feb 20;4(1):132-137. Epub 2018 Dec 20.

Department of Otolaryngology-Head and Neck Surgery University of Miami, Miller School of Medicine Miami Florida.

Objective: To analyze demographic, clinical, surgical, and audiometric factors that may affect hearing outcome following surgery for the semicircular canals (SCC).

Method: This is a retrospective case review of adults who underwent surgeries for superior SCC (SSCC), lateral SCC (LSCC), or posterior SCC (PSCC) and whose data were extracted and analyzed for factors affecting the hearing outcome in these procedures.

Results: Thirteen patients underwent surgery for SSCC, seven cases for the LSCC, one for the PSCC, and one case of combined PSCC/SSCC surgery. Read More

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http://dx.doi.org/10.1002/lio2.239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383314PMC
February 2019
1 Read

Excess of Rare Missense Variants in Hearing Loss Genes in Sporadic Meniere Disease.

Front Genet 2019 15;10:76. Epub 2019 Feb 15.

Otology and Neurotology Group CTS 495, Department of Genomic Medicine, Centre for Genomics and Oncological Research (GENyO), Pfizer, University of Granada, Andalusian Regional Government, Granada, Spain.

Meniere's disease (MD) is a clinical spectrum of rare disorders characterized by vertigo attacks, associated with sensorineural hearing loss (SNHL) and tinnitus involving low to medium frequencies. Although it shows familial aggregation with incomplete phenotypic forms and variable expressivity, most cases are considered sporadic. The aim of this study was to investigate the burden for rare variation in SNHL genes in patients with sporadic MD. Read More

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http://dx.doi.org/10.3389/fgene.2019.00076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385525PMC
February 2019
1 Read

[Caloric test and hearing characteristics in patients with vestibular migraine and Meniere's disease].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):228-231

Department of Otolaryngology, Dalian Medical University First Affiliated Hospital, Dalian, 116011, China.

This study was designed to distinguish vestibular migraine(VM) from Meniere's disease(MD) by comparing age, sex, family history, audiological and vestibular test results in patients with VM or MD. Forty-six patients with suspected VM, 60 patients with confirmed VM, and 60 patients with confirmed MD were studied. All patients were asked for detailed medical history, and then underwent bithermal caloric test and audiological test. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.011DOI Listing
March 2019
3 Reads

[Acoustic absorbance characteristics of wideband tympanometry in patients with Meniere's disease].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):224-227

Department of Otolaryngology Head and Neck Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine; Institute of Ophthalmology, School of Medicine, Shanghai Jiaotong University; Shanghai key Laboratory of Ear and Nose Disease Transformation, Shanghai, 200092, China.

To study acoustic absorbance characteristics of wideband tympanometry in patients with unilateral Meniere's disease. Acoustic absorbance were detected using wideband tympanometry in 36 patients with unilateral Meniere's disease and 39 control subjects excluding inner ear and middle ear disease. All patients with Meniere's disease underwent electrocochleography, gadolinium contrast internal auditory canal MRI, pure tone test. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.010DOI Listing

[Analysis of clinical features of secondary benign paroxysmal positional vertigo].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):220-224

Center of Vertigo Clinic Research of Aerospace, General Hospital of PLA Air Force, Beijing, 100142, China.

To analyze the clinical features of secondary benign paroxysmal positional vertigo (BPPV) and provide evidence for its precise diagnosis and treatment. There were 942 patients with vertigo related to BPPV, including 204 patients with primary BPPV, 592 patients with vestibular migraine (VM), 83 patients with Meniere's disease (MD), 48 patients with vestibular neuronitis (VN), and 15 patients with sudden sensorineural hearing loss (SSNHL) accompanied by vertigo.There were 127 patients with BPPV secondary to vertigo in MD, VN, VM, and SSNHL. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.009DOI Listing
March 2019
1 Read

[The critical thoughts on clinical diagnosis and treatment of Meniere's disease].

Authors:
C F Dai X Y Li

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):196-199

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.002DOI Listing
March 2019
5 Reads

The role of magnetic resonance imaging in Ménière disease: the current state of endolymphatic hydrops evaluation.

Einstein (Sao Paulo) 2019 Feb 25;17(1):eMD4743. Epub 2019 Feb 25.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Technical advances in magnetic resonance imaging have allowed to accurately detect and grade endolymphatic space distension in Ménière disease; this was only possible in post-mortem histological studies until a few years ago. Magnetic resonance imaging rules out other causes of vertigo and hearing loss, and is able to evaluate the cochlear and vestibular compartments of the endolymphatic space using a dedicated protocol. Read More

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http://dx.doi.org/10.31744/einstein_journal/2019MD4743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388723PMC
February 2019
2 Reads

Successful treatment of a child with definite Meniere's disease with the migraine regimen.

Am J Otolaryngol 2019 Feb 18. Epub 2019 Feb 18.

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA; Department of Biomedical Engineering, University of California, Irvine, USA. Electronic address:

Emerging evidence suggests substantial overlap between the symptoms of Meniere's disease (MD) and migraine-related cochlear/vestibular disorders. We report a 5-year-old girl with a 6-month history of left-sided hearing loss followed by daily episodes of vertigo, headache, and vomiting who met the criteria for definite MD. The patient became symptom-free and gained near normal hearing levels after starting on a 6-week migraine diet/lifestyle regimen with riboflavin and magnesium. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.02.004DOI Listing
February 2019
8 Reads

Three-Dimensional Magnetic Resonance Imaging Reveals the Relationship Between the Control of Vertigo and Decreases in Endolymphatic Hydrops After Endolymphatic Sac Drainage With Steroids for Meniere's Disease.

Front Neurol 2019 4;10:46. Epub 2019 Feb 4.

Department of Otolaryngology- Head and Neck Surgery, Nara Medical University, Kashihara, Japan.

Meniere's disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere's disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the hydrostatic pressure and endolymph homeostasis for the inner ear. Read More

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http://dx.doi.org/10.3389/fneur.2019.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369164PMC
February 2019
14 Reads

Neurologic Conditions: Dizziness and Vertigo.

FP Essent 2019 Feb;477:29-39

University of South Alabama College of Medicine Department of Family Medicine, 1601 Center Street, 2N Mobile, AL 36604.

Dizziness is seen frequently in patients in the family medicine and emergency department settings. The differential diagnosis of dizziness can be expansive but with a targeted history and physical examination, a correct diagnosis often can be established and appropriate treatment offered. Common etiologies of dizziness include hypotension, benign paroxysmal positional vertigo (BPPV), and Meniere disease. Read More

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February 2019
8 Reads

Drop attacks, hydrops severity, and disease duration in hydropic ear disease (Menière's).

Authors:
Robert Gürkov

Eur Arch Otorhinolaryngol 2019 05 9;276(5):1553. Epub 2019 Feb 9.

Department of Otorhinolaryngology, Klinikum Bielefeld, Academic Teaching Hospital of the University of Münster, Teutoburger Str. 50, 33604, Bielefeld, Germany.

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http://dx.doi.org/10.1007/s00405-019-05329-4DOI Listing

The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière's disease on MRI.

Neuroradiology 2019 Apr 5;61(4):421-429. Epub 2019 Feb 5.

Department of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Wilrijk, Belgium.

Purpose: There is still a clinical-radiologic discrepancy in patients with Menière's disease (MD). Therefore, the purpose of this study was to investigate the reliability of current MRI endolymphatic hydrops (EH) criteria according to Baráth in a larger study population and the clinical utility of new imaging signs such as a supplementary fourth low-grade vestibular EH and the degree of perilymphatic enhancement (PE) in patients with Menière's disease (MD).

Methods: This retrospective study included 148 patients with probable or definite MD according to the 2015 American Academy of Otolaryngology, Head and Neck Surgery criteria who underwent a 4-h delayed intravenous Gd-enhanced 3D-FLAIR MRI between January 2015 and December 2016. Read More

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http://dx.doi.org/10.1007/s00234-019-02155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431299PMC
April 2019
17 Reads

[The downbeat nystagmus in 2 cases with unilateral Meniere's disease].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;32(22):1751-1753

We retrospectively analyzed 2 patients of unilateral Meniere's disease with downbeat nystagmus. Audiometric test, the Dix-Hallpike maneuver and the supine roll test were performed. Both patients presented with spontaneous nystagmus with downbeat components, and downbeat components were exaggerated by Dix-Hallpike maneuver. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.22.017DOI Listing
November 2018

Vertigo Induced During Coitus.

Front Neurol 2018 11;9:1187. Epub 2019 Jan 11.

Department of Neurology, Seoul National University College of Medicine, Seoul, South Korea.

The aim of this study was to describe the clinical features of vertigo developed during sexual intercourse. We retrospectively reviewed the clinical and laboratory findings of seven patients who reported recurrent vertigo during sexual intercourse. All the patients reported spinning sensation for a few minutes to 1 h, which developed during the coitus. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.01187
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http://dx.doi.org/10.3389/fneur.2018.01187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336730PMC
January 2019
3 Reads

[Possible effect of diabetes and hypertension on the quality of life of patients suffering from Ménière's disease].

Orv Hetil 2019 Jan;160(4):144-150

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem Budapest, Szigony u. 36., 1083.

Introduction: Ménière's disease is a disorder of the inner ear, characterized by episodic rotational vertigo, sensorineural hearing loss, tinnitus, aural pressure and vegetative symptoms. Since the improvement of these symptoms exerts an influence on the patients' quality of life and the condition seems to be incurable, the symptomatic treatment suggests an important question.

Aim: Our study's aim is to evaluate how hypertension and diabetes exert influence on the patients' quality of life and how effective conservative pharmacologic treatment is. Read More

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http://dx.doi.org/10.1556/650.2019.31256DOI Listing
January 2019
5 Reads

Postoperative compensation after neurotomy in Meniere's disease: Retrospective study of 15 cases.

Neurochirurgie 2019 Feb 16;65(1):20-26. Epub 2019 Jan 16.

Service de neurochirurgie, CHU de Limoges, 87000 Limoges, France. Electronic address:

Introduction: Vestibular neurotomy is a functional surgery for Meniere's disease in the event of medical treatment failure. The aim of the study was to assess the efficacy and complications of vestibular neurotomy, and to address the question of postoperative compensation.

Material And Method: All patients included in this retrospective study underwent a vestibular neurotomy at our center between 2009 and 2016. Read More

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http://dx.doi.org/10.1016/j.neuchi.2018.11.002DOI Listing
February 2019
7 Reads

Gadolinium-enhanced MRI reveals dynamic development of endolymphatic hydrops in Ménière's disease.

Braz J Otorhinolaryngol 2018 Dec 20. Epub 2018 Dec 20.

Shanghai East Hospital, Department of Otorhinolaryngology Shanghai, Shanghai, China.

Introduction: Meniere's disease is associated with impaired hearing, tinnitus, vertigo, and aural fullness. Many anatomical studies have suggested idiopathic endolymphatic hydrops as the pathological basis of Meniere's disease, which now can be visualized by using gadolinium -enhanced magnetic resonance imaging of the inner ear.

Objective: To investigate the development of endolymphatic hydrops in Meniere's disease by monitoring the vestibules and cochleae of affected patients. Read More

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http://dx.doi.org/10.1016/j.bjorl.2018.10.014DOI Listing
December 2018
6 Reads

Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome.

Cochrane Database Syst Rev 2018 12 31;12:CD012173. Epub 2018 Dec 31.

Ear Institute, Faculty of Brain Sciences, University College London, London, UK.

Background: Ménière's disease or syndrome is a chronic inner ear disorder that results in sporadic attacks of vertigo, sensorineural hearing loss, aural fullness and tinnitus.There is no definitive treatment for Ménière's disease and treatment options range from dietary modification through medication to surgery.Modification of diet, including restriction of salt, caffeine and alcohol intake, is a management option that is widely recommended to patients with Ménière's as a first-line treatment. Read More

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http://dx.doi.org/10.1002/14651858.CD012173.pub2DOI Listing
December 2018
3 Reads

[Recent immunology research of Meniere's disease].

Authors:
S Y Guo Y Zhang B Liu

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):953-956

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otorhinolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education , Beijing 100730, China.

Inner ear disease is characterized by tinnitus, deafness and vertigo. The pathogenesis remains unknown. In the past, it is considered to be related to vascular disease such as thrombus and hemadostenosis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.12.017DOI Listing
December 2018

[Study on the shift of ocular vestibular evoked myogenic potentials frequency tuning of Meniere's disease].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):904-908

Department of Otorhinolaryngology, Aerospace Center Hospital, Beijing 100049, China.

To study the shift of oVEMP frequency tuning of unilateral Meniere's disease, by analyzing oVEMP of air-conducted tone bursts in various frequencies. From May 2016 to October 2017, 33 patients with unilateral Meniere's from Aerospace Center Hospital were tested for oVEMP in 500 Hz and 1 000 Hz air-conducted tone bursts respectively, and 20 healthy subjects(40 ears), matched for age and sex, were used as healthy control. The amplitudes of the N1-P1 wave and the frequency amplitude ratios of 500/1 000 Hz in affected ears, unaffected ears and normal ears were compared; and receiver operating characteristic curve was analyzed for frequency amplitude ratios of 500/1 000 Hz. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.12.006DOI Listing
December 2018

Clinical Features and Endolymphatic Hydrops in Patients With MRI Evidence of Hydrops.

Ann Otol Rhinol Laryngol 2019 Apr 17;128(4):286-292. Epub 2018 Dec 17.

1 ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.

Objectives:: The purpose of this study was to investigate the correlation between grades of endolymphatic hydrops (ELH) and clinical characteristics and determine the detailed clinical characteristics of Ménière's disease (MD) patients with evidence of hydrops based on magnetic resonance imaging (MRI).

Methods:: One hundred ninety-eight MD patients (396 ears) with MRI evidence of hydrops were included. ELH grades were evaluated using the Nakashima grading standard. Read More

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http://journals.sagepub.com/doi/10.1177/0003489418819551
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http://dx.doi.org/10.1177/0003489418819551DOI Listing
April 2019
14 Reads

Association of Ménière disease with human leukocyte antigen in Taiwanese population.

Ear Nose Throat J 2018 Dec;97(12):396-402

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

The etiology of Ménière disease (MD) is multifactorial; genetic factors seem to play an important role. The associations between MD and human leukocyte antigen (HLA) status have been studied previously in several populations and have shown that the HLA alleles imparting susceptibility varied. In the present study, we explored HLA status in Taiwanese patients with definitive MD. Read More

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http://dx.doi.org/10.1177/014556131809701208DOI Listing
December 2018
9 Reads

Three-Tesla magnetic resonance imaging of the vestibular endolymphatic space: A systematic qualitative description in healthy ears.

Eur J Radiol 2018 Dec 24;109:77-82. Epub 2018 Oct 24.

Neuroradiology Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy; Postgraduate School of Radiodiagnostics, Università degli Studi di Milano, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Background And Purpose: A detailed knowledge of the normal Magnetic Resonance (MR) anatomy of the vestibular endolymphatic space (ES) could be useful to understand the linkage between endolymphatic hydrops (EH) and Ménière's disease (MD). Our aim was to describe the MR anatomy of the vestibular ES as depicted by MR imaging in healthy ears.

Methods: This report describes a single-center retrospective study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183037
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http://dx.doi.org/10.1016/j.ejrad.2018.10.023DOI Listing
December 2018
13 Reads

Vertical head impulse and caloric are complementary but react opposite to Meniere's disease hydrops.

Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

Objectives/hypothesis: Meniere's disease (MD) patients can show normal head impulses despite poor caloric test results. This study aimed to investigate the discrepancy in the vestibulo-ocular reflex (VOR) in MD patients and whether endolymphatic hydrops (EH) influence the VOR.

Study Design: Prospective, cross-sectional observational study. Read More

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http://dx.doi.org/10.1002/lary.27580DOI Listing
December 2018
21 Reads

Serum sickness disease in a patient with alopecia areata and Meniere' disease after PRP procedure.

Dermatol Ther 2019 Mar 8;32(2):e12798. Epub 2019 Jan 8.

Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, The University of Warmia and Mazury, Olsztyn, Poland.

Background: Platelet rich plasma procedure (PRP) is considered to be one of the safest aesthetic procedures. Adverse reactions after PRP administration are extreme rare.

Purpose: We present the patient with serum sickness disease (SSD) after PRP procedure. Read More

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http://dx.doi.org/10.1111/dth.12798DOI Listing
March 2019
17 Reads

Direction-Changing and Direction-Fixed Positional Nystagmus in Patients With Vestibular Neuritis and Meniere Disease.

Clin Exp Otorhinolaryngol 2018 Dec 5. Epub 2018 Dec 5.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objectives: Direction-changing positional nystagmus (PN) was considered to indicate the presence of benign paroxysmal positional vertigo involving lateral semicircular canal in most cases. We investigated the incidence of PN on the supine head-roll test and compared the characteristics of nystagmus in patients with vestibular neuritis (VN) and Meniere disease (MD).

Methods: A retrospective review of patients, who were diagnosed with unilateral VN or unilateral definite MD between September 2005 and November 2011, was conducted. Read More

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http://dx.doi.org/10.21053/ceo.2018.00038DOI Listing
December 2018
7 Reads

Disorders of the inner-ear balance organs and their pathways.

Handb Clin Neurol 2018 ;159:385-401

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Read More

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https://linkinghub.elsevier.com/retrieve/pii/B97804446391650
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http://dx.doi.org/10.1016/B978-0-444-63916-5.00025-2DOI Listing
March 2019
16 Reads

Imaging of Ménière Disease.

Neuroimaging Clin N Am 2019 Feb;29(1):19-28

Department of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, Wilrijk 2610, Belgium.

Visualization of the morphologic substrate of Ménière disease, the endolymphatic hydrops, can be performed using noncontrast or contrast-enhanced MR imaging techniques. Noncontrast MR imaging uses a heavily T2-weighted sequence; however, its reproducibility remains to be confirmed. Contrast-enhanced MR imaging techniques mainly use a 3-dimensional fluid-attenuated inversion recovery sequence after intratympanic gadolinium administration or after a 4-hour delayed intravenous gadolinium administration. Read More

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http://dx.doi.org/10.1016/j.nic.2018.09.002DOI Listing
February 2019
13 Reads

Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?

PLoS One 2018 15;13(11):e0207467. Epub 2018 Nov 15.

Department of Otorhinolaryngology, S.João Hospital Centre, Porto, Portugal.

Introduction: Middle ear application of gentamicin is a common medical treatment for uncontrolled Ménière's disease. The objective of the study was to evaluate the impact of endolymphatic hydrops on inner ear delivery.

Methods: Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207467PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237362PMC
April 2019
18 Reads

Towards personalized medicine in Ménière's disease.

F1000Res 2018 15;7. Epub 2018 Aug 15.

Clinique du Vertige, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg.

Ménière's disease (MD) represents a heterogeneous group of relatively rare disorders with three core symptoms: episodic vertigo, tinnitus, and sensorineural hearing loss involving 125 to 2,000 Hz frequencies. The majority of cases are considered sporadic, although familial aggregation has been recognized in European and Korean populations, and the search for familial MD genes has been elusive until the last few years. Detailed phenotyping and cluster analyses have found several clinical predictors for different subgroups of patients, which may indicate different mechanisms, including genetic and immune factors. Read More

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http://dx.doi.org/10.12688/f1000research.14417.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097350PMC
March 2019
13 Reads

The vestibular aqueduct sign: Magnetic resonance imaging can detect abnormalities in both ears of patients with unilateral Meniere's disease.

J Neuroradiol 2018 Nov 10. Epub 2018 Nov 10.

Department of neuroradiology and MRI, Grenoble university hospital, 38000 Grenoble France; University Grenoble Alpes, 38000 Grenoble, France; IRMaGe, inserm US 17, CNRS UMS 3552, 38000 Grenoble, France.

Background And Purpose: In patients with Meniere's disease (MD), saccular hydrops can only be studied by magnetic resonance imaging (MRI) at a late stage when the disease is already responsible for moderate to severe hearing loss. However, these patients may also present vestibular aqueduct (VA) abnormalities.

Materials And Methods: In this prospective study (38RC14. Read More

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http://dx.doi.org/10.1016/j.neurad.2018.10.003DOI Listing
November 2018
23 Reads

Comorbid Symptoms Occurring During Acute Low-Tone Hearing Loss (AHLH) as Potential Predictors of Menière's Disease.

Front Neurol 2018 29;9:884. Epub 2018 Oct 29.

Department of Otorhinolaryngology, Head and Neck Surgery, Charité- Universitätsmedizin Berlin, Corporate Member of Freie Universität, Berlin Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

Acute low-tone sensorineural hearing loss (ALHL) is a type of idiopathic sudden sensorineural hearing loss. ALHL is rarely a solitary condition but rather co-occurs with vertigo and tinnitus, being an element of contemporary diagnostic criteria for Menière's disease (MD). The goal of our present study was to determine the value of ALHL for the early diagnosis of MD in patients presenting in the emergency room with ALHL as a main complaint. Read More

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http://dx.doi.org/10.3389/fneur.2018.00884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215849PMC
October 2018
6 Reads

Autoimmunity and Otolaryngology Diseases.

J Immunol Res 2018;2018:2747904. Epub 2018 Oct 4.

Department Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1155/2018/2747904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193323PMC
February 2019
2 Reads

Enhanced Vestibulo-Ocular Reflex Responses on vHIT. Is It a Casual Finding or a Sign of Vestibular Dysfunction?

Front Neurol 2018 15;9:866. Epub 2018 Oct 15.

Vestibular Research Laboratory, School of Psychology, The University of Sydney, Sydney, NSW, Australia.

In current clinical practice, when in response to vHIT testing the observed slow-phase eye-velocity responses are significantly higher than head velocity, the most probable cause is considered to be an inadequate collection method or a recording artifact. We present two cases with clinical diagnoses of Menière's Disease: for both cases, enhanced eye velocity responses were measured with a rigorous vHIT testing protocol. In the first case we measured these enhanced responses on each test performed during a 5 year time series; in the second case multiple measurements were obtained from a patient after the radiologic diagnosis of vestibulo-cochlear hydrops. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.00866
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http://dx.doi.org/10.3389/fneur.2018.00866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196253PMC
October 2018
17 Reads

[The correlation between the hearing frequency and staging of Meniere's disease].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;53(10):776-779

Department of Otorhinolaryngology, Peking University People's Hospital, Beijing 100044, China.

To study the relationship between the average hearing of different frequencies and the audiometry staging in patients with Meniere's disease. A total of 259 patients from 1996 to 2016 were collected .All patients underwent pure tone audiometry, of which 93 patients underwent 3 000 Hz audiometry. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.10.011DOI Listing
October 2018

MR Imaging in Menière Disease: Is the Contact between the Vestibular Endolymphatic Space and the Oval Window a Reliable Biomarker?

AJNR Am J Neuroradiol 2018 Nov 18;39(11):2114-2119. Epub 2018 Oct 18.

From the Neuroradiology Unit (G.C., E.S., C. Sina, F.T.), Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy.

Background And Purpose: No reliable MR imaging marker for the diagnosis of Menière disease has been reported. Our aim was to investigate whether the obliteration of the inferior portion of the vestibule and the contact with the stapes footplate by the vestibular endolymphatic space are reliable MR imaging markers in the diagnosis of Menière disease.

Materials And Methods: We retrospectively enrolled 49 patients, 24 affected by unilateral sudden hearing loss and 25 affected by definite Menière disease, who had undergone a 4-hour delayed 3D-FLAIR sequence. Read More

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http://www.ajnr.org/lookup/doi/10.3174/ajnr.A5841
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http://dx.doi.org/10.3174/ajnr.A5841DOI Listing
November 2018
6 Reads

Clinical manifestations of hydropic ear disease (Menière's).

Eur Arch Otorhinolaryngol 2019 Jan 10;276(1):27-40. Epub 2018 Oct 10.

Department of Otorhinolaryngology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.

Introduction: Hydropic ear disease, initially described by and named after Prosper Menière, is one of the most frequent vertigo disorders and one of the most frequent inner ear disorders. It is the syndrome of endolymphatic hydrops which until 2007 could be diagnostically confirmed only by post-mortem histology. In the past, various attempts to formulate clinical diagnostic criteria have been undertaken but were hampered by the inability to ascertain the diagnosis in living patients. Read More

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http://dx.doi.org/10.1007/s00405-018-5157-3DOI Listing
January 2019
19 Reads

Clinical Characteristics of Bilateral Meniere's Disease in a Single Asian Ethnic Group.

Laryngoscope 2019 May 3;129(5):1191-1196. Epub 2018 Oct 3.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea.

Objectives/hypothesis: To identify the clinical characteristics of patients with bilateral Meniere's disease (MD) in an Asian population.

Study Design: Cross-sectional retrospective study.

Methods: We compared the clinical features of bilateral MD (BMD) and unilateral MD (UMD) in 320 Asian patients with single ethnicity. Read More

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http://dx.doi.org/10.1002/lary.27423DOI Listing
May 2019
5 Reads

Intratympanic Therapies in Ménière Disease: Evaluation of Outcomes and Early Vertigo Control.

Laryngoscope 2019 Jan 3;129(1):216-221. Epub 2018 Oct 3.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, U.S.A.

Objective: To evaluate outcomes of intratympanic (IT) dexamethasone and gentamicin in Ménière Disease (MD).

Methods: Charts of adult patients with unilateral definite MD receiving IT gentamicin or dexamethasone from 2005 to 2017 were retrospectively reviewed. All patients had at least 6 months follow-up. Read More

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http://dx.doi.org/10.1002/lary.27392DOI Listing
January 2019
2 Reads

Salivary α-amylase levels in vertigo: Can it be an autonomic dysfunction?

Ear Nose Throat J 2018 Sep;97(9):278-282

Department of Emergency, Izmir Medicalpark Hospital, Izmir, Turkey.

We aim to demonstrate possible autonomic dysfunction based on salivary α-amylase measurements during and after the vertigo attacks associated with Ménière disease (MD) and benign paroxysmal positional vertigo (BPPV). Patients admitted to the emergency room with a diagnosis of vertigo attacks caused by either MD (n = 15) or BPPV (n = 9) constituted the study groups. The control group (n = 10) consisted of volunteer patients admitted to the emergency department with minor soft-tissue trauma. Read More

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http://dx.doi.org/10.1177/014556131809700917DOI Listing
September 2018
7 Reads