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    Oral Tranexamic Acid for the Treatment of Melasma: A Review.
    Dermatol Surg 2018 Apr 19. Epub 2018 Apr 19.
    Skin and Cancer Foundation Inc., Melbourne, Australia.
    Background: Melasma is a common acquired disorder of hyperpigmentation that commonly affects those with skin of color. Tranexamic acid (TXA) is a novel treatment for melasma that has a multimodal mechanism of action.

    Objective: To provide a comprehensive review of the literature regarding the evidence on the mode of action, safety profile, and efficacy of TXA in the treatment of melasma. Read More

    The Safety and Efficacy of Treatment With a 1,927-nm Diode Laser With and Without Topical Hydroquinone for Facial Hyperpigmentation and Melasma in Darker Skin Types.
    Dermatol Surg 2018 Apr 13. Epub 2018 Apr 13.
    Goldman, Butterwick, Groff, Fabi & Wu, Cosmetic Laser Dermatology, San Diego, California.
    Background: The nonablative, fractional, 1,927-nm diode laser is theoretically a safe and effective treatment for hyperpigmentation and melasma in darker skin and may potentiate topical cosmeceutical delivery.

    Objective: To evaluate the use of a nonablative, fractional, 1,927-nm diode laser with and without topical 2% hydroquinone (HQ) cream for moderate-to-severe facial hyperpigmentation in Fitzpatrick skin Types III-V.

    Methods: Forty adults underwent 4 laser treatments at 2-week intervals and were randomized to daily application of 2% HQ cream or moisturizer. Read More

    Dual Effect of Photobiomodulation on Melasma: Downregulation of Hyperpigmentation and Enhanced Solar Resistance-A Pilot Study.
    J Clin Aesthet Dermatol 2018 Apr 1;11(4):28-34. Epub 2018 Apr 1.
    Dr. Barolet is with the Department of Medicine, Dermatology Division, McGill University in Montreal, Québec, Canada, and with the RoseLab Skin Optics Laboratory in Laval, Canada.
    Melasma is a resistant, sun-induced facial hyperpigmentation capable of remaining present for decades with ensuing psychological distress. Treatment is difficult and focuses on an array of measures to reduce skin hyperpigmentation resulting from triggered hyperactive melanocytes. The pathogenesis of melanoma is not clearly understood but it has been reported that some growth factors and specific cell-signaling pathways are involved. Read More

    Sesamol Inhibited Melanogenesis by Regulating Melanin-Related Signal Transduction in B16F10 Cells.
    Int J Mol Sci 2018 Apr 7;19(4). Epub 2018 Apr 7.
    Department of Cosmeceutics, China Medical University, Taichung 40402, Taiwan.
    Melanin is synthesized through a series of interactions catalyzed by melanogenic enzymes such as tyrosinase, dopachrome tautomerase (tyrosinase-related protein-2; TRP-2), and tyrosinase-related protein-1 (TRP-1). Tyrosinase plays a key role in catalysing the initial and limiting steps of melanogenesis. The melanin that results from melanogenesis has the protective effect of absorbing ultraviolet radiation. Read More

    Behaviors and Attitudes Toward Cosmetic Treatments Among Men.
    J Clin Aesthet Dermatol 2018 Mar 1;11(3):42-48. Epub 2018 Mar 1.
    Drs. Girdwichai, Chanprapaph, and Vachiramon are with the Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University in Bangkok, Thailand.
    Cosmetic treatments have gained popularity worldwide. However, little is known about the behaviors and attitudes toward cosmetic treatments in men. The authors sought to explore the behaviors and attitudes toward cosmetic treatments in male patients. Read More

    Double-blind, Placebo-controlled Trial to Evaluate the Effectiveness of Extract in the Treatment of Melasma in Asian Skin: A Pilot Study.
    J Clin Aesthet Dermatol 2018 Mar 1;11(3):14-19. Epub 2018 Mar 1.
    Drs. Goh, Chuah, and Thng are with the National Skin Centre in Singapore.
    Melasma is a common pigmentary disorder with a multifactorial etiology that can hinder its management. The aqueous extract of the fern (PLE), Fernblock (IFC, Madrid, Spain), has demonstrated antioxidant and photoprotective activities and has been used for the treatment of several pigmentary disorders. The aim of this study was to evaluate the efficacy and safety of oral PLE in the treatment of melasma in Asian patients. Read More

    Pathology of tail fan necrosis in the spiny lobster, Jasus edwardsii.
    J Invertebr Pathol 2018 Mar 21;154:5-11. Epub 2018 Mar 21.
    Institute of Marine Science, The University of Auckland, New Zealand; School of Biological Sciences, The University of Auckland, New Zealand.
    Tail fan necrosis (TFN) is the bacterial infection of the tail fan of spiny lobsters which leads to melanosis and erosion of the tail fan tissues. The condition is commonly found among spiny lobsters in aquaculture and commercial fisheries, and greatly reduces their commercial value. This study describes the pathology of TFN by examining the tail fans (telson, uropods) and internal organs (mid-gut, hepatopancreas, heart and gill) of 29 affected wild spiny lobsters (Jasus edwardsii) and 14 unaffected in New Zealand. Read More

    Gender, age, and concomitant diseases of melanosis coli in China: a multicenter study of 6,090 cases.
    PeerJ 2018 8;6:e4483. Epub 2018 Mar 8.
    Department of Gasterology, General Hospital of the Xinjiang Military Region, Urumqi, China.
    Backgrounds And Aims: Melanosis coli (MC) is a noninflammatory, benign, and reversible colonic disorder, but its detection rates in China are unclear. We therefore aimed to analyze the epidemiological characteristics of MC in China.

    Methods: We assessed the detection rates, associated factors and concomitant diseases of MC in the patients who underwent colonoscopy at eight medical centers across five regions of China between January 2006 and October 2016. Read More

    Rare finding of concomitant pseudomelanosis of stomach and duodenum; case report and literature review.
    Gastroenterol Hepatol Bed Bench 2018 ;11(1):86-89
    Division of Gastroenterology and Hepatology, SBH Health System, 4422 Third Ave, Bronx, New York, USA.
    Melanosis of the stomach and duodenum is a rare entity and a striking finding diagnosed by upper gastrointestinal endoscopy. Here, we describe the case of an 83-year-old female, with a complicated medical history, who was referred to gastroenterologist to assess bleeding risk. From the endoscopy, it was determined that she had both melanosis gastri and duodeni. Read More

    α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.
    Theranostics 2018 16;8(7):2031-2043. Epub 2018 Feb 16.
    College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.
    cAMP up-regulates microphthalmia-associated transcription factor subtype M (MITF-M) and tyrosinase (Tyro) in the generation of heavily pigmented melanosomes. Here, we communicate a therapeutic mechanism of hyperpigmented disorder by α-viniferin, an active constituent of . We used cAMP-elevated melanocyte cultures or facial hyperpigmented patches for pigmentation assays, and applied immunoprecipitation, immunobloting, RT-PCR or reporter gene for elucidation of the antimelanogenic mechanism. Read More

    Treatment of melasma using tranexamic acid: what's known and what's next.
    Cutis 2018 Feb;101(2):E7-E8
    Department of Dermatology, Stanford University Medical Center, California, USA.
    Tranexamic acid is a procoagulant agent that is approved by the US Food and Drug Administration for treatment of menorrhagia and to prevent hemorrhage in patients with hemophilia undergoing tooth extractions. Through its inhibitory effects on the plasminogen activation pathway, tranexamic acid also mitigates the UV radiation-induced pigmentation response. Systemic tranexamic acid has consistently been reported as an effective treatment of melasma, though its broad use may be limited by the risk for thromboembolism. Read More

    Melasma in Men: A Review of Clinical, Etiological, and Management Issues.
    J Clin Aesthet Dermatol 2018 Feb 1;11(2):53-59. Epub 2018 Feb 1.
    Dr. Sarkar is a professor at the Department of Dermatology, Maulana Azad Medical College in New Delhi, India.
    Melasma is a common skin condition that affects both men and women. However, it is more commonly seen in women and dark-skinned individuals, such as in Hispanics, Asians, and African Americans who live in areas with intense ultraviolet radiation. Melasma is less common in men, but it negatively affects the quality of life in men as much as it does in women. Read More

    Are Natural Ingredients Effective in the Management of Hyperpigmentation? A Systematic Review.
    J Clin Aesthet Dermatol 2018 Feb 1;11(2):28-37. Epub 2018 Feb 1.
    Dr. Hollinger is with the Department of Dermatology, University of Mississippi Medical Center in Jackson, Mississippi.
    Hyperpigmentation disorders are commonly encountered in dermatology clinics. Botanical and natural ingredients have gained popularity as alternative depigmenting products. We sought to review clinical studies evaluating the use of different natural products in treating hyperpigmentation so clinicians are better equipped to educate their patients. Read More

    Blue Nevi of the Ocular Surface: Clinical Characteristics, Pathologic Features, and Clinical Course.
    Ophthalmology 2018 Mar 15. Epub 2018 Mar 15.
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida. Electronic address:
    Purpose: Blue nevus is a melanocytic tumor that is commonly found in the skin. Extracutaneous presentations, including the ocular surface, are rare. As such, the purpose of this study was to characterize the clinical features and clinical course of congenital melanocytic tumor (blue nevus) of the conjunctiva. Read More

    Nanotechnological advances for cutaneous release of tretinoin: an approach to minimize side effects and improve therapeutic efficacy.
    Curr Med Chem 2018 Mar 12. Epub 2018 Mar 12.
    Medicine Department - Federal University of Sao Paulo (UNIFESP). Brazil.
    The clinical efficacy of the topical tretinoin is widely studied and has been well established for many therapeutic interventions, among some, photoaging, acne, and melasma. However, the side effects, mainly cutaneous irritation, erythema, xerosis and peeling, remain major obstacle to the patient compliance. Besides, the insight regarding the drug delivery profile is essential to understand the therapeutic action of the drug. Read More

    Neurocutaneous melanosis in an adult patient with intracranial primary malignant melanoma: case report and review of the literature.
    World Neurosurg 2018 Mar 9. Epub 2018 Mar 9.
    The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital. Department of Neurosurgery, Suzhou215002, China. Electronic address:
    Objective: To explore the clinical characteristics of neurocutaneous melanosis (NCM) in adult patients in order to help improve diagnosis and treatment of this disease.

    Methods: We present a rare case of an adult patient suffering from neurocutaneous melanosis with malignant melanoma as well as a review Chinese and English literature, and analyze their clinical features.

    Results: There were thirty adult NCM patients, aged 19 to 65 years old, average 27. Read More

    Giant Congenital Melanocytic Nevi: An Update and Emerging Therapies.
    Case Rep Dermatol 2018 Jan-Apr;10(1):24-28. Epub 2018 Feb 8.
    cDepartment of Pediatrics, Richmond University Medical Center, New York, NY, USA.
    Giant congenital melanocytic nevi (GCMN) are a rare occurrence. Gain-of-function mutation in the NRAS gene is found to be associated with GCMN, causing abnormal proliferation of embryonic melanoblasts. The two major complications associated with GCMN are malignant melanoma and neurocutaneous melanosis. Read More

    Population-based incidence of conjunctival tumours in Olmsted County, Minnesota.
    Br J Ophthalmol 2018 Mar 6. Epub 2018 Mar 6.
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
    Aim: To determine population-based incidence of conjunctival tumours in Olmsted County, Minnesota.

    Methods: The Rochester Epidemiology Project medical record linkage system was used to identify patients with conjunctival tumours in Olmsted County (1 January 1980 to 31 December 2015). Records were reviewed for demographics, types of tumours, histopathology, treatment and clinical course. Read More

    CCN1/Cyr61 Stimulates Melanogenesis through Integrin α6β1, p38 MAPK, and ERK1/2 Signaling Pathways in Human Epidermal Melanocytes.
    J Invest Dermatol 2018 Mar 3. Epub 2018 Mar 3.
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, PR China. Electronic address:
    Fibroblast-derived melanogenic paracrine mediators are known to play a role in melanogenesis. To investigate the effect of CCN1 (also called CYR61 or cysteine-rich 61) on melanogenesis, normal human epidermal melanocytes were treated with recombinant CCN1 protein. Our findings show that CCN1 activates melanogenesis through promoting melanosome maturation and up-regulation of MITF, TRP-1, and tyrosinase via the integrin α6β1, p38 MAPK, and ERK signaling pathways. Read More

    Intradermal tranexamic acid injections to prevent post-inflammatory hyperpigmentation after solar lentigo removal with a Q-switched 532-nm Nd:YAG laser.
    J Cosmet Laser Ther 2018 Mar 5:1-7. Epub 2018 Mar 5.
    a Department of dermatology, Chulabhorn International College of Medicine , Thammasat University , Pathum Thani , Thailand.
    Introduction: Post-inflammatory hyperpigmentation (PIH) after solar lentigo removal using a Q-switched (QS) 532-nm Nd:YAG laser is a cause for concern. This study aimed to evaluate the efficacy and safety of intradermal injections of tranexamic acid (TA) at reducing the risk of PIH after QS 532-nm Nd:YAG laser treatment of solar lentigines.

    Methods: Twenty-five patients with 50 solar lentigines on forearms underwent QS 532-nm Nd:YAG laser treatment. Read More

    Massive intussusception caused by a solitary Peutz-Jeghers type hamartomatous polyp.
    Ann R Coll Surg Engl 2018 Apr 27;100(4):e91-e93. Epub 2018 Feb 27.
    Surgical Department, General Hospital of Agrinio , Agrinio, Aitoloakarnania , Greece.
    Intussusception is a rare cause of intestinal obstruction in adults and represents a diagnostic challenge for the surgeon. In the majority of cases, presenting symptoms are not specific, making preoperative diagnosis difficult. Several medical conditions may cause intestinal intussusception. Read More

    Natural options for management of melasma, a review.
    J Cosmet Laser Ther 2018 Feb 20:1-12. Epub 2018 Feb 20.
    a Laser Research Centre, Faculty of Health Sciences , University of Johannesburg , Doornfontein , South Africa.
    A blemish free, even-toned skin is universally associated with healthy skin. This reasoning makes people desire to have a flawless skin. Melanin is a naturally occurring pigment in humans. Read More

    Topical 3% tranexamic acid enhances the efficacy of 1064-nm Q-switched neodymium-doped yttrium aluminum garnet laser in the treatment of melasma.
    J Cosmet Laser Ther 2018 Feb 20:1-6. Epub 2018 Feb 20.
    a Division of Dermatology, Chulabhorn International College of Medicine , Thammasat University , Pathumthani , Thailand.
    Background: A QS-NdYAG laser (QSNYL) and topical tranexamic acid (TA) have been widely used. However, no study has yet reported the efficacy of using both QSNYL and TA as a combined treatment for melasma.

    Objectives: To evaluate the efficacy and adverse effects of topical 3% TA combined with 1064-nm QSNYL as a treatment for melasma. Read More

    Pulsed dye laser versus intense pulsed light in melasma: a split-face comparative study.
    J Dermatolog Treat 2018 Feb 23:1-8. Epub 2018 Feb 23.
    a Dermatology and Venereology Department , Tanta University , Tanta , Egypt.
    Background: Recent reports suggest that melasma may have a vascular component. Vascular targeting lasers and light treatment can be a therapeutic option that will provide benefits to the patients.

    Objectives: To compare the efficacy and tolerability of pulsed dye laser (PDL) and intense pulsed light in treatment of melasma. Read More

    Picosecond Laser Treatment for Tattoos and Benign Cutaneous Pigmented Lesions (Secondary publication).
    Laser Ther 2017 Dec;26(4):274-281
    Kasai Clinic for Plastic Surgery.
    Background And Aims: The selective removal of tattoos and benign cutaneous pigmented lesions with laser energy evolved rapidly with the development of the nanosecond-domain Q-switched laser (ns-laser). Recently, however, a series of picosecond-domain lasers (ps-lasers) with pulsewidths less than 1 ns has become commercially available, enabling more efficient and faster removal of pigmented lesions in the field of dermatologic laser surgery.

    Rationale Behind The Ps-laser: The efficacy of the ns-laser depended on the theory of selective photothermolysis, whereby an extremely short pulse width was delivered less than the thermal relaxation time (TRT) of a target. Read More

    Pigmentation Disorders: Diagnosis and Management.
    Am Fam Physician 2017 Dec;96(12):797-804
    Norton Audobon Hospital, Louisville, KY, USA.
    Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Read More

    Treatment of Melasma with Pulsed-Dye Laser and 1,064-nm Q-Switched Nd:YAG Laser: A Split-Face Study.
    Ann Dermatol 2018 Feb 26;30(1):1-7. Epub 2017 Dec 26.
    Department of Dermatology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
    Background: Melasma is an acquired pigmentary disorder that is often therapeutically challenging. Recent evidence suggests that vascular abnormalities are involved in melasma pathogenesis. Pulsed-dye laser (PDL) is considered as standard therapy for vascular lesions. Read More

    Fractional erbium-doped yttrium aluminum garnet laser-assisted drug delivery of hydroquinone in the treatment of melasma.
    Clin Cosmet Investig Dermatol 2018 3;11:13-20. Epub 2018 Jan 3.
    Dermatology Unit, Department of Medical Applications of Lasers (MAL), National Institute of Laser Enhanced Sciences (N.I.L.E.S.), Cairo University, Giza, Egypt.
    Background: Melasma is a difficult-to-treat hyperpigmentary disorder. Ablative fractional laser (AFL)-assisted delivery of topically applied drugs to varied targets in the skin has been an area of ongoing study and research.

    Objective: The objective of this study was to evaluate the efficacy and safety of fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser as an assisted drug delivery for enhancing topical hydroquinone (HQ) permeation into the skin of melasma patients. Read More

    Clinical profile of 300 men with facial hypermelanosis.
    J Dermatol Case Rep 2017 Dec 1;11(2):20-24. Epub 2017 Dec 1.
    Department of Dermatology, Venereology & Leprosy, Dr. R. P. Govt. Medical College, Kangra (Tanda)-176001 (Himachal Pradesh), India.
    Background: Facial hypermelanosis is a significant cause of cosmetic disfigurement, social embarrassment and psychological morbidity affecting quality of life.

    Objective: To study clinicoepidemlogic patterns of facial hypermelanoses among men.

    Material And Methods: Medical records of all adult males presenting with facial hypermelanoses were analyzed for this retrospective cross sectional study for demographic details, duration, cosmetic usage, sun exposure, drug intake, infections, systemic or cutaneous diseases, and family history of hypermelanotic dermatosis. Read More

    Histopathological findings in pregnancy associated cutaneous hyperpigmentation.
    J Cutan Pathol 2018 Apr 9;45(4):286-289. Epub 2018 Feb 9.
    Department of Dermatology, Hospital El Bierzo, Ponferrada, Spain.
    Hyperpigmentation in pregnancy is a common phenomenon, experienced to some degree by up to 90% of pregnant women. It mainly involves sun-exposed areas, but it can extend to non-exposed zones. Cases with extensive hyperpigmentation are rarely reported. Read More

    [Phakomatosis pigmentovascularis cesioflammea: a case report].
    Arch Argent Pediatr 2018 Feb;116(1):e121-e124
    Servicio de Dermatología, Hospital Nacional de Pediatría "Prof. Dr. J. P. Garrahan", Ciudad Autónoma de Buenos Aires.
    Phakomatosis pigmentovascularis (PPV) is a syndrome characterized by the association of a vascular nevus with a congenital pigmented lesion (epidermal nevus, nevus spilus, and dermal melanocytosis). There are different types of PPV according to the pigmentary nevus associated with the vascular malformation. Patients may present only the cutaneous condition or have systemic manifestations, among them, trauma, neurological and ophthalmological disorders. Read More

    Double Blind, Placebo Controlled Evaluation of a Novel Skin Lightening Agent.
    J Drugs Dermatol 2018 Jan;17(1):113-115
    Melasma remains a troubling problem for physicans and patients alike. It is a chronic irregular, symmetric hyperpigmentation seen most often in women. In this study, a unique combination of ingredients with non-irritating properties was tested for treatment of melasma. Read More

    [A woman with hyperpigmentation and dark urine].
    Ned Tijdschr Geneeskd 2017 ;161(0):D1944
    Antoni van Leeuwenhoek Ziekenhuis, afd. Medische Oncologie, Amsterdam.
    A 54-year-old patient was evaluated because of fever shortly after she had started treatment of a BRAF-mutated melanoma with BRAF- and MEK-inhibitors. Diffuse hyperpigmentation of the skin was noted as an incidental finding. She also had darkly coloured urine. Read More

    Pigmented epithelioid melanocytoma with nodal melanosis: A rare cause of cystic cervical lymphadenopathy.
    Head Neck 2018 Apr 2;40(4):E33-E35. Epub 2018 Jan 2.
    Department of General Surgery, Sengkang General Hospital, Singapore.
    Background: Head and neck malignancies often present as firm, solid nodal masses. However, malignancies arising from Waldeyer's Ring may give rise to cystic lymph nodes.

    Methods: A 57-year-old man was referred for left-sided neck swelling of 2 weeks' duration. Read More

    Efficacy of Intense Pulse Light Therapy and Tripple Combination Cream Versus Intense Pulse Light Therapy and Tripple Combination Cream Alone in Epidermal Melasma Treatment.
    J Coll Physicians Surg Pak 2018 Jan;28(1):13-16
    Department of Dermatology, PGMI, Lady Reading Hospital, Peshawar.
    Objective: To compare the efficacy of intense pulse light therapy (IPL) and triple combination cream (TCC) versus intense pulse light therapy and triple combination cream alone in epidermal melasma treatment, downgrading MASI score to more than 10.

    Study Design: Randomized controlled trial.

    Place And Duration Of Study: Dermatology Department, Lady Reading Hospital, Peshawar, from August 2014 to January 2015. Read More

    Patients' self-esteem before and after chemical peeling procedure.
    J Cosmet Laser Ther 2017 Dec 29:1-3. Epub 2017 Dec 29.
    a Department of Dermatology and Venereology , Andreas Sygros Hospital , Athens , Greece.
    Introduction: Chemical peeling is a safe method, widely used to treat a variety of skin conditions and reduce the aging effects. This study aims to evaluate self-esteem among adolescents who undergo chemical peelings.

    Material And Methods: One hundred and twenty six patients constituted the study group. Read More

    Skin autofluorescence reflects individual seasonal UV exposure, skin photodamage and skin cancer development in organ transplant recipients.
    J Photochem Photobiol B 2018 Jan 6;178:577-583. Epub 2017 Dec 6.
    Department of Dermato-venerology, Bispebjerg University Hospital, 2400 Copenhagen, Denmark.
    Importance: Ultraviolet radiation (UVR)-induced skin cancers varies among organ transplant recipients (OTRs). To improve individual risk assessment of skin cancer, objectively quantified skin photodamage is needed.

    Objectives: We measured personal UVR-exposure dose in OTRs and assessed the relation between individual UVR exposure, skin cancer and objectively measured photodamage in terms of skin autofluorescence, pigmentation, and black light-evaluated solar lentigines. Read More

    Diffuse cutaneous melanosis: rare complication of metastatic melanoma.
    An Bras Dermatol 2017 ;92(5 Suppl 1):62-64
    Private practice - Brasília (DF), Brazil.
    Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. Read More

    Long-term mucocutaneous adverse effects of imatinib in Indian chronic myeloid leukemia patients.
    Int J Dermatol 2018 Mar 20;57(3):332-338. Epub 2017 Dec 20.
    Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    Background: Short-term mucocutaneous adverse effects are well documented with imatinib. However, studies on long-term adverse effects and in the ethnic population are lacking.

    Objective: To study the long-term mucocutaneous adverse effects of imatinib and factors predicting these adverse effects. Read More

    Lasers in Melasma: A Review with Consensus Recommendations by Indian Pigmentary Expert Group.
    Indian J Dermatol 2017 Nov-Dec;62(6):585-590
    Consultant Dermatologist, Skintrendz, Himayat Nagar, Hyderabad, India.
    Lasers have come up as the newest therapeutic modality in dermatological conditions including melasma. In this article, as a group of experts from Pigmentary Disorders Society in collaboration with South Asian Pigmentary Disorders Forum (SPF), we have tried to discuss the lasers which have been used in melasma and formulate simple consensus guidelines. Following thorough literature search, we have summarised the rationale of using the lasers and the supporting evidences have also been provided. Read More

    Chemical Peels in Melasma: A Review with Consensus Recommendations by Indian Pigmentary Expert Group.
    Indian J Dermatol 2017 Nov-Dec;62(6):578-584
    Dermatologist Specialist, Dr RML Hospital and PGIMS, New Delhi, India.
    Melasma is a notorious dermatosis, often resistant to treatment. Chemical peeling constitutes an acceptable option of management of melasma (of any type and duration). In this article, as a group of experts from Pigmentary Disorders Society (PDS) in collaboration with South Asian Pigmentary Forum (SPF), we have tried to elaborate the various chemical peeling agents for the treatment of melasma. Read More

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