391 results match your criteria Melanotic Neuroectodermal Tumor of Infancy


Ototoxicity after platinum-based chemotherapy in the treatment of melanotic neuroectodermal tumour of infancy.

Oncol Lett 2020 May 5;19(5):3411-3416. Epub 2020 Mar 5.

Department of Maxillofacial Orthopaedics and Orthodontics, University of Medical Sciences, 60-780 Poznań, Poland.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare infantile tumor that originates from mesenchymal-neuroectodermal cells, the treatment of which uses platinum derivatives that can affect hearing loss. The present study evaluated the long-term effects of ototoxicity following chemotherapy with cisplatin, vincristine, cyclophosphamide, teniposide and adriamycin in a 10-year-old patient after surgical removal of a MNTI tumor at the age of 8 months. Audiometric tests (high-frequency tonal audiometry, speech audiometry, speech acoustics, tympanometry and absorbance measurements) were performed during a 10-year follow-up after receiving chemotherapy. Read More

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http://dx.doi.org/10.3892/ol.2020.11447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115066PMC

Melanotic Neuroectodermal Tumor of Infancy, a Rapidly Growing Maxillary Alveolar Mass: A Case Report.

J Dent (Shiraz) 2020 Mar;21(1):77-80

Dept. of Periodontics, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Melanotic neuroectodermal tumor of infancy is a rare, rapidly growing, painless, pigmented neoplasm with neural crest derivation. It usually occurs during the first year of life and there is a prominent predilection for the maxilla. The purpose of the present report is to describe additional case of melanotic neuroectodermal tumor of infancy of maxilla in a 6-month-old infant male. Read More

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http://dx.doi.org/10.30476/DENTJODS.2019.44910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036348PMC

Melanotic Neuroectodermal Tumor of Infancy: A Rare Case Report.

Cureus 2019 Dec 31;11(12):e6521. Epub 2019 Dec 31.

Department of Pathology, Mahatma Gandhi Medical College & Hospital, Jaipur, IND.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented neoplasm of neural crest origin that most commonly arises in the maxilla of neonates and infants during the first year of life. We report the case of a three-month-old female child who presented with a 15-day history of intraoral swelling. Radiologically, the tumor was detected in the right maxilla, which was removed by wide local excision. Read More

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http://dx.doi.org/10.7759/cureus.6521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991144PMC
December 2019

Melanotic neuroectodermal tumor of infancy to the skull: case-based review.

Childs Nerv Syst 2020 Apr 17;36(4):679-688. Epub 2020 Jan 17.

Department of Neurosurgery, University Hospital of Basel, Basel, Switzerland.

Background: Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor, which usually occurs in infants under the age of one. Early diagnosis and radical surgery seem to be critical for long-term cure.

Case Presentation: We describe a case of a 4-month-old boy with a MNTI to the skull. Read More

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http://dx.doi.org/10.1007/s00381-020-04509-6DOI Listing

Melanotic neuroectodermal tumor of infancy arising from the skull: report of an unusual case, review of the literature, and a diagnostic approach.

Childs Nerv Syst 2020 Mar 3;36(3):469-475. Epub 2020 Jan 3.

Neurosurgery Department, Pediatric Hospital "Prof. Dr. Juan P. Garrahan", Buenos Aires, Argentina.

Introduction: Melanotic neuroectodermal tumor of infancy is a rare neoplasm mainly seen in children under 1 year of life. The most common location of the tumor is the maxilla followed by the cranial vault. Surgery is the treatment of choice and outcome mainly depends on extent of resection. Read More

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http://dx.doi.org/10.1007/s00381-019-04476-7DOI Listing

Melanotic neuroectodermal tumor of infancy in ovary: A rare case report.

Medicine (Baltimore) 2019 Dec;98(49):e18181

Department of Pediatric Surgery, Hunan Children's Hospital.

Rationale: Melanotic neuroectodermal tumor of infancy (MNTI) is an extremely rare benign pigmented neoplasm of neural crest origin with rapid expansile growth and a high recurrence rate. It is predominantly found in infants of <1 year of age, involvement of the head-and-neck region is the most common presentation though it is reported at other sites including mediastinum, shoulder, thigh, foot, epididymis, uterus and ovary. The patient reported here is the third case of MNTI presenting in an ovary, and the first reported in the infant ovary. Read More

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http://dx.doi.org/10.1097/MD.0000000000018181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919528PMC
December 2019

Melanotic neuroectodermal tumour of infancy presenting as a lytic lesion in femur: a rare tumour at a rare site with an unusual behaviour.

BMJ Case Rep 2019 Oct 5;12(10). Epub 2019 Oct 5.

Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

Melanotic neuroectodermal tumour of infancy (MNTI) is an uncommon tumour, predominantly occurring in head and neck, mostly maxilla, but also in skull and mandible. Although a benign lesion, it is known to recur in 15%-27% of cases, and rarely, may undergo malignant transformation. We present a case of a 5-month-old female patient, who presented with a gradually progressive swelling in the right thigh. Read More

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http://dx.doi.org/10.1136/bcr-2019-231959DOI Listing
October 2019
2 Reads

Melanotic Neuroectodermal Tumor of Infancy Arising in the Skull and Brain: A Systematic Review.

World Neurosurg 2019 Oct 8;130:170-178. Epub 2019 Jul 8.

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. Electronic address:

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented craniofacial tumor of infants. This study aimed to analyze the literature on MNTI arising from the skull and brain. A systematic literature review was performed and 91 patients reported in 78 articles were identified from 1918 to 2019. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.07.017DOI Listing
October 2019
3 Reads

Melanotic neuroectodermal tumor of infancy: A rare entity.

J Oral Maxillofac Pathol 2019 Feb;23(Suppl 1):134-137

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm with a predilection for the head-and-neck region. Approximately 472 cases reported in literature till date. We report an unusual case of MNTI in a 1-month old child. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_237_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421908PMC
February 2019
22 Reads

Melanotic Neuroectodermal Tumor Presenting as Endolymphatic Sac Tumor.

Ear Nose Throat J 2019 Oct-Nov;98(9):537-539. Epub 2019 Apr 7.

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA, USA.

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http://dx.doi.org/10.1177/0145561319839936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202569PMC
April 2020
6 Reads

Congenital Granular Cell Epulis: Classic Presentation and Its Differential Diagnosis.

Head Neck Pathol 2020 Mar 19;14(1):208-211. Epub 2019 Mar 19.

Division of Pathology, Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON, Canada.

Congenital granular cell epulis (CGCE) is an uncommon lesion of unclear pathogenesis. It occurs predominantly in female newborns with a predilection site of the maxillary alveolar ridge. The mass enlarges prenatally but the growth arrests after birth. Read More

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http://link.springer.com/10.1007/s12105-019-01025-1
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http://dx.doi.org/10.1007/s12105-019-01025-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021869PMC
March 2020
30 Reads

Melanotic neuroectodermal tumour of infancy: Refining the surgical approach.

Int J Oral Maxillofac Surg 2019 Oct 11;48(10):1307-1312. Epub 2019 Mar 11.

Great Ormond Street Hospital, London, UK.

Melanotic neuroectodermal tumours of infancy (MNTI) are particularly rare and although predominantly benign, are infiltrative and locally aggressive. Presenting in the first year of life, prompt diagnosis and effective management are critical in minimizing morbidity and the risk of recurrence. A retrospective review of 11 MNTI managed at Great Ormond Street Hospital (GOSH) from 2000 to 2017 was undertaken. Read More

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http://dx.doi.org/10.1016/j.ijom.2019.02.011DOI Listing
October 2019
10 Reads

A 32-Year-Old Women with an Intra- and Paraspinal, Extradural Mass at T10-T12.

Brain Pathol 2019 03;29(2):309-310

University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/bpa.12708DOI Listing
March 2019
20 Reads

Difficult Nasal Intubation Using Airway Scope for a Child With Large Tumor.

Anesth Prog 2018 ;65(4):251-254

Anesthesiology and Clinical Physiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

We report a case of difficult nasal intubation utilizing a Pentax-Airway scope AWS-100. A 4-month-old female with a rapidly growing melanotic neuroectodermal tumor was scheduled for resection under general anesthesia. The tumor was a large rubbery mass located in the middle of the mandible. Read More

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http://dx.doi.org/10.2344/anpr-65-04-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318730PMC
October 2019
9 Reads

Melanotic Neuroectodermal Tumor of Infancy: a Clinicopathological Case Report.

Braz Dent J 2018 Jul-Aug;29(4):400-404

Department of Oral Diagnosis, Piracicaba Dental School, UNICAMP - Universidade de Estadual de Campinas, Piracicaba, SP, Brazil.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that affects mainly children under 1 year of age. A 4-month-old boy was referred for evaluation of a lesion with 1 month of evolution. Intra-oral examination detected a firm upon palpation submucosal nodular mass, measuring 1. Read More

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http://dx.doi.org/10.1590/0103-6440201801787DOI Listing
March 2019
38 Reads

Retinal Anlage Tumor of Epididymis: A Diagnostic Challenge on Cytology.

Acta Cytol 2019;63(1):73-74. Epub 2018 Nov 19.

Department of Paediatric Surgery, Chacha Nehru Bal Chikitsalaya, Delhi, India.

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http://dx.doi.org/10.1159/000494124DOI Listing
March 2019
9 Reads

Melanotic Neuroectodermal Tumor of Infancy.

Arch Pathol Lab Med 2018 11;142(11):1358-1363

From the Divisions of Anatomic and Clinical Pathology (Dr Soles) and Anatomic Pathology (Drs Wilson and Lucas), Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor.

Context.—: Melanotic neuroectodermal tumor of infancy, albeit rare and generally regarded as benign, is an important tumor to recognize because of its rapid growth, potential for local recurrence, and small round blue cell morphology, which can lead to misdiagnosis of a malignant neoplasm.

Objective. Read More

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http://www.archivesofpathology.org/doi/10.5858/arpa.2018-024
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http://dx.doi.org/10.5858/arpa.2018-0241-RADOI Listing
November 2018
16 Reads

Epididymal melanotic neuroectodermal tumor of infancy: A rare cause of scrotal mass in an infant.

J Clin Ultrasound 2019 Feb 5;47(2):100-103. Epub 2018 Nov 5.

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, benign neoplasm of neural crest origin more commonly seen in the craniofacial region. We report a case of MNTI of the epididymis in a 6-month-old male child with emphasis on the sonographic appearance which has not been previously described. In this case, the mass was inseparable from the testicle and therefore the differential diagnosis considered both extratesticular and intratesticular masses. Read More

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http://doi.wiley.com/10.1002/jcu.22658
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http://dx.doi.org/10.1002/jcu.22658DOI Listing
February 2019
42 Reads

Melanotic Neuroectodermal Tumor of Infancy: Case Report and Review of Management.

J Oral Maxillofac Surg 2019 Feb 5;77(2):315-320. Epub 2018 Oct 5.

Professor and Vice Chairman, Department of Oral and Maxillofacial Surgery, University of Maryland School of Dentistry, Baltimore, MD.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented tumor of the head and neck, which most commonly presents during the first year of life. Most cases present in the bones of the craniofacial region, including the maxilla (60.3%), skull (18. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391183110
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http://dx.doi.org/10.1016/j.joms.2018.09.033DOI Listing
February 2019
52 Reads

Melanotic neuroectodermal tumor of infancy of the jaw bones: Update on the factors influencing survival and recurrence.

Head Neck 2018 12 2;40(12):2749-2756. Epub 2018 Nov 2.

Oral Surgery and Pathology Department, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil.

The aim of the present study was to integrate the available data published on melanotic neuroectodermal tumor of infancy (MNTI) of the jaw bones. An electronic search was undertaken in April 2018. Hundred forty-seven publications and 371 patients were included. Read More

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http://doi.wiley.com/10.1002/hed.25514
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http://dx.doi.org/10.1002/hed.25514DOI Listing
December 2018
14 Reads

Novel therapeutic compound acridine-retrotuftsin action on biological forms of melanoma and neuroblastoma.

J Cancer Res Clin Oncol 2019 Jan 26;145(1):165-179. Epub 2018 Oct 26.

Department of Organic Chemistry, Gdansk University of Technology, Narutowicza St 11/12, 80-233, Gdansk, PL, Poland.

Purpose: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO)-Pro-Lys-Thr-OCH]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies. Thus, we analyzed the action of ART on pairs of biological forms of melanoma (amelanotic and melanotic) and neuroblastoma (dopaminergic and cholinergic) with regard to proliferation, mechanism of cell death, and effect on the activity of tricarboxylic acid cycle (TAC) enzymes. Read More

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http://link.springer.com/10.1007/s00432-018-2776-4
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http://dx.doi.org/10.1007/s00432-018-2776-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326014PMC
January 2019
18 Reads

Melanotic neuroectodermal tumor of infancy: A rare pediatric head and neck lesion.

Pediatr Dermatol 2018 Nov 4;35(6):e389-e390. Epub 2018 Sep 4.

Department of Dermatology, University of New Mexico, Albuquerque, New Mexico.

Melanotic neuroectodermal tumors of infancy are rare tumors arising from the neural crest and typically present during the first 12 months of life. The majority involve the facial bones, although melanotic neuroectodermal tumors of infancy of the skull and extremities have been observed with less frequency, as in the present case. This entity may initially be presented to the dermatologist as a scalp mass and should be considered in the differential diagnosis of infants with rapidly growing head and neck lesions. Read More

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http://doi.wiley.com/10.1111/pde.13601
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http://dx.doi.org/10.1111/pde.13601DOI Listing
November 2018
40 Reads

Melanotic neuroectodermal tumour of infancy of the jaws: an analysis of diagnostic features and treatment.

Int J Oral Maxillofac Surg 2019 Jan 28;48(1):1-8. Epub 2018 Aug 28.

Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

The purpose of this study was to integrate the available published data on melanotic neuroectodermal tumour of infancy (MNTI) of the jaws into a comprehensive analysis of its clinical/radiological features, with emphasis on the predictive factors associated with recurrence. Eligibility criteria included publications with sufficient clinical/radiological/histological information to confirm the diagnosis. A total of 288 publications reporting 429 MNTI cases were included. Read More

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http://dx.doi.org/10.1016/j.ijom.2018.08.006DOI Listing
January 2019
4 Reads

Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy.

J Oral Maxillofac Pathol 2018 May-Aug;22(2):260-262

Department of Surgical and Hospital Dentistry, University of Louisville School of Dentistry, Louisville, Kentucky, USA.

While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_161_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097382PMC
August 2018
7 Reads

Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens.

Oral Dis 2018 Nov 10;24(8):1484-1491. Epub 2018 Jul 10.

Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Objectives: To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa.

Materials And Methods: A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of any pigmented lesion were retrieved. Read More

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http://dx.doi.org/10.1111/odi.12924DOI Listing
November 2018
11 Reads

Use of Technological Aids in the Resection of a Rare Maxillofacial Tumor of Infancy.

Cleft Palate Craniofac J 2018 10 30;55(9):1308-1312. Epub 2018 May 30.

2 Dell Children's Medical Center, Dell Medical School, University of Texas at Austin, Austin, TX, USA.

Melanotic neuroectodermal tumor of infancy is a rare maxillofacial tumor, usually presenting within the first year of life, often a benign locally aggressive lesion, with wide local excision providing the best opportunity of cure. In past reports, direct tissue visualization guided resection, with occasional need for reoperation to clear margins. In this case report, a method is presented to achieve clear margins in surgery using virtual surgical planning and surgical stealth navigation. Read More

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http://dx.doi.org/10.1177/1055665618763375DOI Listing
October 2018
15 Reads

Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla.

Einstein (Sao Paulo) 2018 May 14;16(2):eRC4025. Epub 2018 May 14.

Universidade Estadual da Paraíba, Campina Grande, PB, Brazil.

Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. Read More

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http://dx.doi.org/10.1590/S1679-45082018RC4025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998940PMC
May 2018
9 Reads

Spontaneous Regression of Diffuse Periosteal Melanotic Neuroectodermal Tumor of Infancy in the Tibia, With 13-Year Follow-up.

J Pediatr Hematol Oncol 2019 03;41(2):148-151

Departments of Pathology, Radiology, and Pediatric Hematology-Oncology, Loma Linda University Health, Loma Linda, CA.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare entity primarily affecting the craniofacial bones during the first year of life, with only 5 reported cases involving peripheral long bones. We herein present a case of MNTI in the tibia of an infant, with a somewhat atypical presentation, and a noteworthy clinical course characterized by progressive spontaneous resolution without therapy, thus sparing the child the trauma of amputation. There is no evidence of active residual or recurrent disease with 13-year follow-up. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001130DOI Listing
March 2019
10 Reads

Melanotic neuroectodermal tumor of infancy: A rare case report.

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S44-S47

Department of Histopathology, National Reference Labrotory, Dr Lal Path Labs Ltd, New Delhi, India.

Melanotic neuroectodermal tumor of infancy is a rare benign but locally aggressive neoplasm of neural crest origin with a high recurrence rate. It usually affects infants of < 1 year of age. Involvement of maxilla of an infant is the most common presentation although cases outside this setting have been reported. Read More

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http://www.jomfp.in/text.asp?2018/22/4/44/224616
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http://dx.doi.org/10.4103/jomfp.JOMFP_197_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824516PMC
January 2018
18 Reads

Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: A French multicenter study.

J Craniomaxillofac Surg 2018 Feb 12;46(2):201-206. Epub 2017 Dec 12.

Department of Maxillofacial and Plastic Surgery, Hôpital Universitaire Necker-Enfants Malades, 75015, Paris, France; Université Paris Descartes, 75006, Paris, France; Laboratory for Oral and Molecular Pathology, INSERM, UMRS 1138, Centre de Recherche des Cordeliers, 75006, Paris, France. Electronic address:

Objectives: Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck is a rare entity with uncertain clinical behavior. Radical surgical resection is the current recommended treatment, however this can cause severe aesthetic and functional sequelae. The aim of this study was to clinically characterize MNTIs and to stratify risk factors that may influence locoregional recurrence. Read More

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http://dx.doi.org/10.1016/j.jcms.2017.12.001DOI Listing
February 2018
30 Reads
2.600 Impact Factor

A Simplified Overview of World Health Organization Classification Update of Central Nervous System Tumors 2016.

J Neurosci Rural Pract 2017 Oct-Dec;8(4):629-641

Department of Pathology and Emergency Laboratory, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India.

After 8 years, an update of central nervous system (CNS) tumors was published in 2016 after 2007. First time ever, molecular markers along with histology have been used in classification of any tumor. Major changes are seen in glioma and medulloblastoma groups. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_168_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709890PMC
December 2017
27 Reads

Melanotic Neuroectodermal Tumor of Infancy of the Upper Arm.

Med Princ Pract 2017 27;26(6):582-585. Epub 2017 Nov 27.

Objective: To present a case of a 6-month-old infant with melanotic neuroectodermal tumor of infancy (MNTI) in the upper arm.

Clinical Presentation And Intervention: A 6-month-old female presented with a well-circumscribed lesion of the upper arm at the Children's Hospital Zagreb. A biopsy was performed and microscopy revealed 2 cell populations consisting of small neuroblastic cells and larger melanin-containing epithelial cells. Read More

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https://www.karger.com/Article/FullText/485744
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http://dx.doi.org/10.1159/000485744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848479PMC
October 2018
32 Reads

Melanotic neuroectodermal tumor of infancy: a rare presentation of an extremely rare neoplasm and diagnostic implications in Gombe, Nigeria.

Pan Afr Med J 2017 4;28. Epub 2017 Sep 4.

Department of Preventive Dentistry, Bayero University Kano, Nigeria.

Melanotic neuro-ectodermal tumor of infancy is very rare. A unique neoplasm of the formative years, it typically involves the face or cranium; possesses rapid, expansile growth; presents as a firm swelling and displays a high rate of recurrence. Its rarity and unique features make diagnosis and management quite challenging. Read More

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http://dx.doi.org/10.11604/pamj.2017.28.5.9394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681010PMC
December 2017
11 Reads

Melanotic neuroectodermal tumour of infancy: A case report and differential diagnosis.

Neuroradiol J 2018 Aug 10;31(4):434-439. Epub 2017 Nov 10.

4 Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, UK.

Melanotic neuroectodermal tumour of infancy is an uncommon pigmented neoplasm of neural crest origin. It was first described in 1918 by Krompecher, known as congenital melanocarcinoma at that time. Although it is generally agreed upon that it is a benign entity, it is locally aggressive and has a significant recurrent risk, reported to be between 10-15%. Read More

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http://dx.doi.org/10.1177/1971400917741770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111430PMC
August 2018
38 Reads

Melanotic neuroectodermal tumour of infancy: An enigmatic tumour with unique cytomorphological features.

Cytopathology 2018 02 13;29(1):104-108. Epub 2017 Oct 13.

Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/cyt.12483DOI Listing
February 2018
5 Reads

Prenatal Diagnosis of a Melanotic Neuroectodermal Tumor of Infancy (MNTI): A Case Report With a Favorable Outcome After Chemotherapy Failure and Incomplete Resection.

J Pediatr Hematol Oncol 2018 05;40(4):320-324

Unit of Plastic and Maxillofacial Surgery.

We present the case of a woman referred to our department at 34 weeks of pregnancy with a fetal ultrasonographic scan showing a mass that had developed within the right maxilla with invasion of the orbit. A retrospective examination showed that this tumor had been present since the 12th week of pregnancy. At 39+4 weeks of gestation, a boy was born. Read More

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http://dx.doi.org/10.1097/MPH.0000000000000982DOI Listing
May 2018
29 Reads

Melanotic Neuroectodermal Tumor of Infancy in the Maxilla.

J Craniofac Surg 2018 Jan;29(1):e28-e30

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir, Turkey.

Melanotic neuroectodermal tumor of infancy is uncommon and has rapid expansile growth. Melanotic neuroectodermal tumor of infancy is a very rare and benign but locally aggressive neoplasm that originates from neural crest and is composed of relatively primitive pigment-producing cells. The lesion commonly affects the maxilla of infants during the first year of life. Read More

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http://dx.doi.org/10.1097/SCS.0000000000003993DOI Listing
January 2018
8 Reads

Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review.

Pediatr Dev Pathol 2017 Sep-Oct;20(5):411-415. Epub 2017 Jan 25.

1 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.

Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity and rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month-old male, presented with a history of worsening left hemiscrotal swelling for 1 week. Read More

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http://dx.doi.org/10.1177/1093526616686437DOI Listing
May 2019
15 Reads

Primary leptomeningeal primitive neuroectodermal tumor: A difficult entity to diagnose.

Indian J Pathol Microbiol 2017 Apr-Jun;60(2):247-249

Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

A 25-year-old male presented with difficulty in walking, loss of vision, and seizures. A clinical possibility of craniospinal meningeal pathology was considered. On computed tomography (CT) scan and magnetic resonance imaging, there was an enhancement of leptomeninges with few ring-enhancing lesions in both frontal lobes and right frontoparietal region. Read More

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http://dx.doi.org/10.4103/0377-4929.208376DOI Listing
February 2018
10 Reads

Asymptomatic Pigmented Lesions of the Gingiva.

JAMA Dermatol 2017 10;153(10):1045-1046

Section of Oral and Maxillofacial Pathology, Division of Dermatopathology, Department of Dermatology, University of Pennsylvania Health System, Philadelphia.

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2017.1614DOI Listing
October 2017
9 Reads

Anaesthetic Management of a Neuroectodermal Tumor of Infancy: A Rare Case Report.

Anesth Essays Res 2017 Jan-Mar;11(1):251-253

Department of Anaesthesiology, TNMC and BYL Nair Hospital, Mumbai, Maharashtra, India.

Melanotic neuroectodermal tumor of infancy is a relatively uncommon osteolytic-pigmented neoplasm that primarily affects the jaws of infants. We report a 5-month-old male child who presented with a swelling in the right upper tooth region of upper jaw in which we face difficult mask ventilation as well as difficult intubation. Wide surgical excision was performed under general anesthesia. Read More

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http://dx.doi.org/10.4103/0259-1162.186863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341631PMC
March 2017
10 Reads

Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: report of a malignant case.

J Neurosurg Pediatr 2017 May 24;19(5):538-545. Epub 2017 Feb 24.

Departments of 1 Paediatric Neurosurgery.

Melanotic neuroectodermal tumor of infancy is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, growing rapidly and developing during the 1st year of life. It most commonly arises from the maxilla, cranial vault, and mandible. Occasionally, it exhibits malignant behavior with local lymph nodes involvement. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/19/5/ar
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http://dx.doi.org/10.3171/2016.11.PEDS16509DOI Listing
May 2017
54 Reads

Melanotic neuroectodermal tumor of infancy: Cytology and histopathology of a rare lesion at an uncommon site.

Diagn Cytopathol 2017 02 7;45(2):173-175. Epub 2016 Nov 7.

Department of Pathology and Surgery Dayanand Medical, College and Hospital Ludhiana, Ludhiana, Punjab, India.

Melanotic neuroectodermal tumour of infancy is a rare, pigmented neoplasm generally arising in infants during the first year of life. The cytological features are rarely described in the literature. This case due to its rarity and unusual site emphasising the cytopathological features and the necessity of histology for differentiating it from other round cell tumours has been presented. Read More

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http://dx.doi.org/10.1002/dc.23624DOI Listing
February 2017
21 Reads

Melanotic neuroectodermal tumour of infancy presenting as an undifferentiated round cell tumour in the soft tissue of the forearm.

Pathology 2017 Jan 1;49(1):87-90. Epub 2016 Dec 1.

Department of Pathology, Ghent University and Ghent University Hospital, Ghent, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025164039
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http://dx.doi.org/10.1016/j.pathol.2016.10.006DOI Listing
January 2017
13 Reads

Melanotic Neuroectodermal Tumor of Infancy with Involvement of the Superior Sagittal Sinus.

Pediatr Neurosurg 2017 6;52(1):36-40. Epub 2016 Sep 6.

Departments of Radiology and Neurosurgery, Le Bonheur Children's Hospital, Memphis, Tenn., USA.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare lesion that typically manifests in the first year of life, most commonly involving the facial bones. We present 2 infants with MNTI involving the posterior skull with associated compression of the superior sagittal sinus (SSS). A review of the anatomical locations of MNTI is offered, and the implications of SSS involvement are described. Read More

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http://dx.doi.org/10.1159/000445954DOI Listing
March 2017
11 Reads

Primary Melanotic Schwannoma with Typical Histology.

J Coll Physicians Surg Pak 2016 Aug;26(8):707-9

Department of Surgery, The Aga Khan University Hospital, Karachi.

We present a case of a 17-year male with a soft tissue density spreading from the neural foramina (T3) of the spinal cord and involving the right upper thoracic cavity. We managed the patient through surgical intervention and resected the complete tumor. Gross definition and microscopic findings of the resected tissue revealed the definitive diagnosis of melanotic schwannoma. Read More

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http://dx.doi.org/2411DOI Listing
August 2016
13 Reads
0.320 Impact Factor

A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.

BMC Cancer 2016 08 12;16:629. Epub 2016 Aug 12.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7HE, UK.

Background: Melanotic neuroectodermal tumor of infancy (MNTI) is exceptionally rare and occurs predominantly in the head and neck (92.8 % cases). The patient reported here is only the eighth case of MNTI presenting in an extremity, and the first reported in the fibula. Read More

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http://dx.doi.org/10.1186/s12885-016-2669-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983003PMC
August 2016
21 Reads
2 Citations
3.362 Impact Factor

Salivary gland anlage tumor.

Indian J Pathol Microbiol 2016 Jul-Sep;59(3):431-3

Department of Pathology, Max Super Speciality Hospital, New Delhi, India.

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http://dx.doi.org/10.4103/0377-4929.188147DOI Listing
March 2017
18 Reads

Salivary gland anlage tumor in a neonate.

Indian J Pathol Microbiol 2016 Jul-Sep;59(3):273

Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.

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http://dx.doi.org/10.4103/0377-4929.188116DOI Listing
March 2017
8 Reads

Melanotic Neuroectodermal Tumor of Infancy.

J Clin Diagn Res 2016 Jun 1;10(6):ZJ07-8. Epub 2016 Jun 1.

Professor and Head, Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences , New Delhi, India .

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http://dx.doi.org/10.7860/JCDR/2016/18206.8009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963796PMC
June 2016
46 Reads