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    351 results match your criteria Melanotic Neuroectodermal Tumor of Infancy

    1 OF 8

    Anaesthetic Management of a Neuroectodermal Tumor of Infancy: A Rare Case Report.
    Anesth Essays Res 2017 Jan-Mar;11(1):251-253
    Department of Anaesthesiology, TNMC and BYL Nair Hospital, Mumbai, Maharashtra, India.
    Melanotic neuroectodermal tumor of infancy is a relatively uncommon osteolytic-pigmented neoplasm that primarily affects the jaws of infants. We report a 5-month-old male child who presented with a swelling in the right upper tooth region of upper jaw in which we face difficult mask ventilation as well as difficult intubation. Wide surgical excision was performed under general anesthesia. Read More

    Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: report of a malignant case.
    J Neurosurg Pediatr 2017 May 24;19(5):538-545. Epub 2017 Feb 24.
    Departments of 1 Paediatric Neurosurgery.
    Melanotic neuroectodermal tumor of infancy is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, growing rapidly and developing during the 1st year of life. It most commonly arises from the maxilla, cranial vault, and mandible. Occasionally, it exhibits malignant behavior with local lymph nodes involvement. Read More

    Melanotic neuroectodermal tumor of infancy: Cytology and histopathology of a rare lesion at an uncommon site.
    Diagn Cytopathol 2016 Nov 7. Epub 2016 Nov 7.
    Department of Pathology and Surgery Dayanand Medical, College and Hospital Ludhiana, Ludhiana, Punjab, India.
    Melanotic neuroectodermal tumour of infancy is a rare, pigmented neoplasm generally arising in infants during the first year of life. The cytological features are rarely described in the literature. This case due to its rarity and unusual site emphasising the cytopathological features and the necessity of histology for differentiating it from other round cell tumours has been presented. Read More

    Melanotic Neuroectodermal Tumor of Infancy with Involvement of the Superior Sagittal Sinus.
    Pediatr Neurosurg 2017 6;52(1):36-40. Epub 2016 Sep 6.
    Departments of Radiology and Neurosurgery, Le Bonheur Children's Hospital, Memphis, Tenn., USA.
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rare lesion that typically manifests in the first year of life, most commonly involving the facial bones. We present 2 infants with MNTI involving the posterior skull with associated compression of the superior sagittal sinus (SSS). A review of the anatomical locations of MNTI is offered, and the implications of SSS involvement are described. Read More

    A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
    BMC Cancer 2016 Aug 12;16:629. Epub 2016 Aug 12.
    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7HE, UK.
    Background: Melanotic neuroectodermal tumor of infancy (MNTI) is exceptionally rare and occurs predominantly in the head and neck (92.8 % cases). The patient reported here is only the eighth case of MNTI presenting in an extremity, and the first reported in the fibula. Read More

    Neurogenic tumors and tumor-like lesions of the oral and maxillofacial region: A clinicopathological study.
    Saudi Dent J 2016 Apr 10;28(2):76-9. Epub 2016 Feb 10.
    Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
    Objective: Oral and maxillofacial lesions of neural origin are rare soft tissue neoplasms. The aim of the present study is to review the epidemiological data of oral and maxillofacial neurogenic lesions submitted for diagnosis to our laboratory over a 31-year period (August 1984-March 2015).

    Materials And Methods: The available formalin-fixed embedded specimens, Hematoxylin and Eosin slides, demographic and clinical data were retrieved. Read More

    Pitfalls and uncertain prognosis in pathological diagnosis of psammomatous melanotic schwannoma.
    J Clin Neurosci 2016 Nov 25;33:236-239. Epub 2016 Jul 25.
    Department of Pathology and Laboratory Medicine, University of Toronto, 27 King's College Cir, Toronto, ON M5S 1A1, Canada; Li Ka Shing Knowledge Institute, Toronto, ON, Canada; Department of Laboratory Medicine, St. Michael's Hospital, Toronto, ON, Canada. Electronic address:
    A 20-year-old woman presenting with a pelvic mass identified as a psammomatous melanotic schwannoma (PMS) with atypical histological features was later found to have family history of cardiac myxomas consistent with Carney's complex. The BRAF V600E mutation was absent in the tumor. Read More

    Metastatic Melanotic Neuroectodermal Tumor of Infancy: Report of a Case and Review of the Literature.
    J Oral Maxillofac Surg 2016 Dec 12;74(12):2431-2440. Epub 2016 Jun 12.
    Professor and Chair, Department of Oral and Maxillofacial Surgery, LSU Health Sciences University, Shreveport, LA.
    Melanotic neuroectodermal tumors of infancy (MNTI) are rapidly growing pigmented tumors that occur predominantly within bony head and neck structures. There are fewer than 400 cases reported in the literature with the majority affecting the maxilla. Locations in other intraosseous and extraosseous structures have been characterized, including the mandible (6% of MNTIs). Read More

    Mandibular melanotic neuroectodermal tumor of infancy: a role for neoadjuvant chemotherapy.
    Eur Arch Otorhinolaryngol 2016 Dec 23;273(12):4629-4635. Epub 2016 Apr 23.
    Department of Otolaryngology Head and Neck Surgery, American University of Beirut Medical Center, 6th Floor, Hamra, Beirut, 1107 2020, Lebanon.
    Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a rare, locally aggressive neoplasm with a predilection for the head and neck area, most commonly occurring in the maxilla. The vast majority of treatment modalities for all cases of MNTI to date have involved surgical intervention only, with just 9.6 % involving some sort of chemotherapy, radiotherapy, or a combination of the prior mentioned modalities. Read More

    Melanotic neuroectodermal tumor of infancy.
    J Clin Neurosci 2016 Sep 16;31:205-7. Epub 2016 Apr 16.
    Department of Diagnostic Radiology, Yale School of Medicine, BOX 208042, Tompkins East 2, 333 Cedar Street, New Haven, CT 06520-8042, USA. Electronic address:
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented craniofacial tumor of newborns and infants. We report the imaging findings of a 3-month old male patient with a maxillary MNTI. Detailed discussion on imaging features on various magnetic resonance sequences and CT scan are included. Read More

    Reconstruction of anterior maxillary defect with buccal pad fat after excision of melanotic neuroectodermal tumor of infancy.
    Ann Maxillofac Surg 2015 Jul-Dec;5(2):234-6
    Unit of Oral and Maxillofacial Surgery, Oral Health Sciences Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    This paper highlights a rare case of melanotic neuroectodermal tumor of infancy involving the anterior maxilla in a 3-month-old infant. The tumor was excised completely, and the defect was reconstructed with a bilateral buccal pad of fat. The patient has been followed for 2 years without any evidence of recurrence. Read More

    Melanotic schwannoma of the L5 root.
    Neuroradiol J 2016 Jun 11;29(3):219-21. Epub 2016 Mar 11.
    Pathology Department, Bahçeşehir University, İstanbul, Turkey.
    Melanotic neoplasm of the central nervous system is rare and the majority of them are metastatic. Melanotic schwannoma (MS) is an unusual variant of nerve sheath neoplasm accounting for less than 1% of primary nerve sheath tumors. A case involving a 36-year-old man with MS at the L5 root is presented. Read More

    Melanotic Neuroectodermal Tumor of Infancy in the Epididymis: A Brief Report and Review of the Role of Chemotherapy in Management.
    J Pediatr Hematol Oncol 2016 Apr;38(3):e144-6
    *St Joseph's Children's Hospital, Paterson, NJ †Rady Children's Hospital-San Diego, San Diego, CA.
    Melanotic neuroectodermal tumor of infancy is a rare benign tumor of neural crest origin. The tumor generally presents in the jawbones; however, it occasionally occurs in extracranial sites. Although 95% of these tumors present within the first year of life and 15% in extracranial locations, we report an unusual case of a 15-month-old male with melanotic neuroectodermal tumor of infancy of the epididymis. Read More

    Melanotic neuroectodermal tumor of infancy in the soft tissue of the forearm: report of a case.
    Int J Clin Exp Pathol 2015 1;8(10):13584-9. Epub 2015 Oct 1.
    Department of Pathology, Children's Hospital of Fudan University Shanghai, China.
    Melanotic neuroectodermal tumor of infancy is rare. Only 3 cases have been reported in the soft tissue of the extremities up to date. It has a typically biphasic feature in morphology. Read More

    Obturator Prostheses for Melanotic Neuroectodermal Tumor of Infancy in the Maxilla.
    J Craniofac Surg 2016 Jan;27(1):e64-5
    *Dental Oncology Service, Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo †Oral Diagnosis Department, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
    Melanotic neuroectodermal tumor of infancy frequently affects the maxilla. A communication between the oral and nasal cavities can be created by surgery. The authors rehabilitated a young patient with obturator prostheses to correct feeding. Read More

    Melanotic neuroectodermal tumor of infancy in the skull: a case report.
    Turk J Pediatr 2015 Mar-Apr;57(2):183-5
    Department of Neurosurgery , Pamukkale University Faculty of Medicine, Private Denizli Surgery Hospital, Denizli, Turkey.
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rarely occurring neoplasm of neural crest origin, appearing in children during the first year of life. MNTI is a benign tumor but is nonetheless locally aggressive; it usually originates from the maxilla and the mandible. Recognition of the diagnostic features of MNTI is important, so that it may be differentiated from benign lesions (dermoid or epidermoid cysts, vascular lesions) as well as from malignant lesions such as small round cell tumors. Read More

    Protumorigenic M2-like phenotype cell infiltration in the melanotic neuroectodermal tumor of infancy.
    Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Feb 10;121(2):173-9. Epub 2015 Dec 10.
    Professor of Stomatology, Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, UNESP-Univ Estadual Paulista, School of Dentistry, São José dos Campos, Brazil. Electronic address:
    Objective: The aim of this study is to report 2 cases of melanotic neuroectodermal tumor of infancy (MNTI), emphasizing the analysis of intratumoral immune cells by immunohistochemistry.

    Study Design: Case 1: A 6-month-old girl presented with a 3-cm tumor in the anterior region of the left maxilla. Case 2: A 4-month-old boy presented with a 4-cm tumor in the anterior region of the left maxilla. Read More

    Melanotic Neuroectodermal Tumor of Infancy Presenting with Fast Growing Scrotal Swelling: A Case Report and Literature Review.
    Pediatr Dev Pathol 2015 Dec 15. Epub 2015 Dec 15.
    6 Children's Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, Calif Pathology and Laboratory Medicine.
    Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity, rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month old male, presented with a history of worsening left hemiscrotal swelling for one week. Read More

    Clinicopathological features of melanotic neuroectodermal tumor of infancy: Report of two cases.
    Auris Nasus Larynx 2016 Aug 18;43(4):451-4. Epub 2015 Nov 18.
    Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
    Melanotic neuroectodermal tumor of infancy (MNTI) is an extremely rare, pigmented neoplastic entity of neural crest origin. Histological and immunohistochemical profiles indicate the presence of two components, small rounded neuroblast-like cellular areas and areas with large melanin-containing cells which consist of combination of neural, melanocytic, and epithelial cell types. Here we present two interesting cases of infants with MNTI which have different clinicopathological features. Read More

    Extensive Melanotic Neuroectodermal Tumor of Infancy.
    Head Neck Pathol 2016 Sep 18;10(3):349-53. Epub 2015 Nov 18.
    Department of Head and Neck Surgery, Albert Sabin Hospital of Fortaleza, Fortaleza, Ceará, Brazil.
    The melanotic neuroectodermal tumor of infancy (MNTI) is a rare childhood neoplasm with an alarming but classical clinical presentation. We present the case of a 2-month-old male infant treated with surgery for an aggressive MNTI on the alveolar process of the maxilla. Radiographic examination showed a diffuse osteolytic radiolucent lesion in the right maxilla, and displacement and dysmorphic changes in the developing primary tooth buds. Read More

    Cyclodextrin-modified MEKC method for quantification of selected acidic metabolites of catecholamines in the presence of various biogenic amines. Application to diagnosis of neuroblastoma.
    J Chromatogr B Analyt Technol Biomed Life Sci 2015 Oct 10;1003:27-34. Epub 2015 Sep 10.
    Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland. Electronic address:
    The main aim of the presented study was to develop a reliable and non-time-consuming method for the simultaneous separation of biogenic amines (BAs) like noradrenalin, adrenalin, dopamine and their main metabolites - homovanillic acid (HVA), vanillylmandelic acid (VMA), 3,4-dihydroxyphenylacetic acid (DOPAC) - in urine samples. To achieve this, the validated α-cyclodextrin (α-CD)-modified micellar electrokinetic chromatography method with DAD was proposed. The optimized separation parameters were as follows: background electrolyte was composed of 10mM sodium tetraborate decahydrate, 30mM SDS, 15% (v/v) methanol and 25mM α-CD, adjusted to pH 9. Read More

    Melanotic neuroectodermal tumour of infancy: surgical and chemotherapeutic management.
    Ir J Med Sci 2016 Aug 28;185(3):753-6. Epub 2015 Jun 28.
    Department of Oral and Maxillofacial Surgery, St James's Hospital, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.
    Melanotic neuroectodermal tumour of infancy (MNTI) is a rare pigmented neoplasm of neural crest origin. It usually presents in the first year of life in the maxilla as a fast growing lesion. We describe the case of a 3-month-old boy who presented with an enlarging swelling of left maxillary alveolus. Read More

    BRAFV600E Mutation in Melanotic Neuroectodermal Tumor of Infancy: Toward Personalized Medicine?
    Pediatrics 2015 Jul;136(1):e267-9
    Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil
    The melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that primarily affects the maxilla of infants during their first year of life. Complete resection is the conventional treatment and recurrence rates vary from 10% to 60%. The recurrent tumors grow more aggressively and can invade other anatomic structures, such as the nasal cavity, the orbit, and the skull base. Read More

    Melanotic neuroectodermal tumour of infancy: a case report.
    J Can Dent Assoc 2015 ;81:f7
    Melanotic neuroectodermal tumour of infancy is a rare benign pigmented tumour that typically appears in the first year of life. We report an atypical presentation of this tumour, associated with an erupted primary tooth in a 7-month-old boy. We discuss the clinical, radiographic and histologic features of this rare tumour, as well as its surgical management and the follow-up treatment plan. Read More

    Subdural extramedullary melanotic schwannoma of the thoracic spinal cord: a case report.
    Turk Neurosurg 2015 ;25(2):326-31
    The First Hospital of Jilin University, Department of Neurosurgery,Changchun, Jilin, China.
    Melanotic schwannoma is a rare "Schwann" cell tumor characterized by the deposition of melanin in the cell cytoplasm. Melanotic schwannoma varies greatly in terms of morphology and clinical manifestations. Here, we describe a patient with subdural extramedullary melanotic schwannoma of the thoracic spinal cord. Read More

    Melanotic Neuroectodermal Tumor of Infancy: A Systematic Review.
    J Oral Maxillofac Surg 2015 Oct 7;73(10):1946-56. Epub 2015 Apr 7.
    Wendy and Keith Wellin Endowed Chair in Head and Neck Surgery; Vice Chair, Clinical Affairs; Vice Chair and Director, Division of Head and Neck Oncologic Surgery; Professor and Director, Division of Head and Neck Oncology, Head and Neck Tumor Center, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC. Electronic address:
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rare tumor, usually diagnosed within the first year of age, with a predilection for the maxilla. Although the tumor is usually benign, its rapidly growing nature and ability to cause major deformities in surrounding structures necessitate early diagnosis and intervention. It is important that medical and dental specialists are prepared to make the diagnosis and proceed with appropriate intervention. Read More

    Congenital neurocristic tumor presenting as an isolated calvarial defect in an infant: case report.
    J Neurosurg Pediatr 2015 Jul 3;16(1):46-9. Epub 2015 Apr 3.
    Departments of 1 Neurosurgery and.
    In infants, the presence of a cranial defect may be due to a variety of traumatic, inflammatory, neoplastic, and congenital abnormalities. Differentiation between these possible etiologies is facilitated by clinical presentation, patient history, and physical examination. Congenital cutaneous neural crest-derived lesions are unlikely to be considered in a patient presenting with an asymptomatic cranial defect without overlying mass or skin pigmentation. Read More

    Testicular and paratesticular tumors and tumor-like lesions in the first 2 decades.
    Semin Diagn Pathol 2014 Sep 15;31(5):323-81. Epub 2014 Jul 15.
    The James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
    The spectrum of testicular tumors and tumor-like lesions that affect young patients (defined for purposes of this article as less than 20 years old) differs significantly from that in an older age group. Although germ cell tumors remain the single largest category, they are a smaller proportion than in adults. Furthermore the pathogenesis and behavior of comparably named germ cell tumors differ depending on whether or not they have developed in prepubertal or postpubertal patients. Read More

    Melanotic neuroectodermal tumor of infancy: A case report and review of the surgical treatment.
    Oncol Lett 2015 Jan 4;9(1):29-34. Epub 2014 Nov 4.
    Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China.
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, fast-growing, benign tumor originating from the neural crest. The tumor most often occurs during the first year of life. The predilection site of MNTI is the anterior maxilla, whereas lesions of the mandible are uncommon and account for only 6% of all cases. Read More

    A deep penetrating facial congenital melanocytic tumor with bone involvement and ipsilateral eye blindness.
    Am J Dermatopathol 2015 Jan;37(1):e5-e11
    Departments of *Dermatology, †Pediatric Oncology, ‡Nuclear Medicine, §Ophthalmology, and ¶Pathology, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel; ‖Department of Pathology, Hadassah Medical Center, Jerusalem, Israel; **Department of Dermatology, NorthWestern University School of Medicine, Chicago, IL; and ††Department of Radiology, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel.
    Bone involvement has been described in tumors with melanocytic differentiation such as melanotic neuroectodermal tumor of infancy, and very rarely in cellular blue nevi and neurocristic cutaneous hamartoma. We present an unusual case of facial congenital melanocytic tumor that involved the underlying bones and maxillary sinus and led to unilateral blindness. A newborn with a large red bluish patch with peripheral brown and black macules overlying marked swelling on the left side of his face was presented. Read More

    Congenital salivary gland anlage tumor - in utero and postnatal imaging.
    Pediatr Radiol 2015 Mar 23;45(3):453-6. Epub 2014 Aug 23.
    Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45040, USA,
    We present a case of an infant with congenital salivary gland anlage tumor, with fetal and postnatal imaging. To the best of our knowledge, this is the first case describing the in utero imaging findings of salivary gland anlage tumor. A fetal MRI was performed secondary to the clinical finding of polyhydramnios, which identified a nasopharyngeal mass. Read More

    Melanotic neuroectodermal tumor of infancy: a wolf in sheep's clothing.
    Ann Otol Rhinol Laryngol 2015 Feb 16;124(2):97-101. Epub 2014 Jul 16.
    Division of Oral and Maxillofacial Surgery, Hofstra North-Shore Long Island Jewish Health System, New Hyde Park, New York, USA.
    Introduction: The melanotic neuroectodermal tumor of infancy (MNTI) is an exceptionally rare neoplasm. Despite their potential for local invasion, MNTI are considered benign neoplasms. Sporadic cases have been reported of MNTI acting in a malignant fashion; however, the majority of these tumors were of extragnathic origin. Read More

    [Pineal anlage tumor in a 8-month-old boy. The first case reported in Spanish language].
    Rev Med Inst Mex Seguro Soc 2014 ;52 Suppl 2:S90-3
    Servicio de Patología, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México.
    Background: The pineal anlage tumor is a very infrequent malign neoplasm. Even though it has been documented in literature, it is not listed yet in the World Health Organization's last nervous system classification (2007). It is a primitive pineal tumor with neuroepithelial and ectomesenchyme differentiation. Read More

    [Melanotic neuroectodermal tumors of infancy: Current state of knowledge].
    Bull Cancer 2014 Jun;101(6):626-36
    Centre Oscar-Lambret, Unité d'oncologie pédiatrique, 3, rue Frédéric-Combemale, 59000 Lille, France.
    Melanotic Neuroectodermal Tumors of Infancy (MNTI), also known as melanotic progonoma are rare tumors affecting young children. The main locations are primarily head, neck and cranial vault. Complete surgical resection remains the standard treatment for these tumors leading to healing in the majority of cases. Read More

    Oral melanotic neuroectodermal tumor of infancy.
    J Indian Soc Pedod Prev Dent 2014 Jan-Mar;32(1):71-3
    Department of Pedodontics and Preventive Dentistry, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
    Melanotic neuroectodermal tumor of infancy (MNTI) is an extremely rare, benign neoplasm of neural crest origin composed of relatively primitive pigment-producing cells. It usually affects new born or infants of <1 year of age, generally involving the face or cranium. This case report describes a 4-month-old child with MNTI involving the anterior region of maxilla. Read More

    Non malignant maxillary lesions: our experience.
    Indian J Otolaryngol Head Neck Surg 2013 Jul 6;65(Suppl 1):74-9. Epub 2012 Mar 6.
    Department of Pathology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Reserch Foundation, Gannavaram, Andhra Pradesh India.
    A wide variety of lesions occur in maxilla. Non specificity of clinical and radiological features makes diagnosis of these lesions a difficult task. We report six interesting cases of maxillary swelling among a total number of 37 such lesions of maxilla. Read More

    Melanotic neuroectodermal tumor of infancy: A rare case report.
    Contemp Clin Dent 2013 Oct;4(4):559-62
    Department of Pedodontics & Preventive Dentistry, Kamineni Institute of Dental Sciences, Narketpally, Nizamabad, Andhra Pradesh, India.
    Melanotic neuroectodermal tumor of infancy (MNTI) is a relatively uncommon osteolytic-pigmented neoplasm that primarily affects the jaws of infants. The early onset and its rapid disfiguring spread necessitate early diagnosis. A 4-month-old male child reported with the complaint of swelling in the right back tooth region of the upper jaw, which rapidly increased in size causing disfigurement of the face. Read More

    Melanotic neuroectodermal tumor of infancy in an African-indigenous patient from the Amazon: a case report.
    Head Face Med 2013 Nov 25;9:35. Epub 2013 Nov 25.
    Oral radiology department, Dentistry posgraduation program, Federal University of Pará, Belém, PA, Brazil.
    Melanotic neuroectodermal tumor of infancy (MNTI) is a rare condition that occurs normally in the anterior maxilla of infants aged <1 year. The use of clinical and imaging tools for MNTI is extremely important to prevent problems with function as well as the aesthetic features in a breastfeeding child. Brazil is a multiethnic country with a poor epidemiological policy and little data to track the incidence of certain diseases, including MNTI. Read More

    GI tract tumors with melanocytic differentiation.
    Adv Anat Pathol 2013 Nov;20(6):398-406
    *Department of Pathology, Division of Anatomic Pathology, Penn State Milton S. Hershey Medical Center, Hershey, PA †Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH.
    Gastrointestinal (GI) tract tumors with melanocytic differentiation may present significant diagnostic challenges both for the pathologist and the clinician. This comprehensive review discusses the relatively common as well as rare entities that have melanocytic differentiation in the GI tract. Clinical, histologic, immunohistochemical and molecular features are discussed along with prognosis and differential diagnosis. Read More

    Melanotic neuroectodermal tumor of infancy in the maxilla.
    Case Rep Dent 2013 8;2013:726815. Epub 2013 Sep 8.
    Department of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, Brazil ; Residency Program in Oral and Maxillofacial Surgery at Conjunto Hospitalar do Mandaqui, São Paulo, SP, Brazil.
    Melanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increasing swelling in the left cheek. Read More

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