377 results match your criteria Melanotic Neuroectodermal Tumor of Infancy


Difficult Nasal Intubation Using Airway Scope for a Child With Large Tumor.

Anesth Prog 2018 ;65(4):251-254

Anesthesiology and Clinical Physiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

We report a case of difficult nasal intubation utilizing a Pentax-Airway scope AWS-100. A 4-month-old female with a rapidly growing melanotic neuroectodermal tumor was scheduled for resection under general anesthesia. The tumor was a large rubbery mass located in the middle of the mandible. Read More

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http://dx.doi.org/10.2344/anpr-65-04-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318730PMC
January 2018

Melanotic Neuroectodermal Tumor of Infancy: a Clinicopathological Case Report.

Braz Dent J 2018 Jul-Aug;29(4):400-404

Department of Oral Diagnosis, Piracicaba Dental School, UNICAMP - Universidade de Estadual de Campinas, Piracicaba, SP, Brazil.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that affects mainly children under 1 year of age. A 4-month-old boy was referred for evaluation of a lesion with 1 month of evolution. Intra-oral examination detected a firm upon palpation submucosal nodular mass, measuring 1. Read More

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http://dx.doi.org/10.1590/0103-6440201801787DOI Listing
December 2017
9 Reads

Melanotic Neuroectodermal Tumor of Infancy.

Arch Pathol Lab Med 2018 Nov;142(11):1358-1363

From the Divisions of Anatomic and Clinical Pathology (Dr Soles) and Anatomic Pathology (Drs Wilson and Lucas), Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor.

Context.—: Melanotic neuroectodermal tumor of infancy, albeit rare and generally regarded as benign, is an important tumor to recognize because of its rapid growth, potential for local recurrence, and small round blue cell morphology, which can lead to misdiagnosis of a malignant neoplasm.

Objective. Read More

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http://www.archivesofpathology.org/doi/10.5858/arpa.2018-024
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http://dx.doi.org/10.5858/arpa.2018-0241-RADOI Listing
November 2018
8 Reads

Epididymal melanotic neuroectodermal tumor of infancy: A rare cause of scrotal mass in an infant.

J Clin Ultrasound 2019 Feb 5;47(2):100-103. Epub 2018 Nov 5.

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, benign neoplasm of neural crest origin more commonly seen in the craniofacial region. We report a case of MNTI of the epididymis in a 6-month-old male child with emphasis on the sonographic appearance which has not been previously described. In this case, the mass was inseparable from the testicle and therefore the differential diagnosis considered both extratesticular and intratesticular masses. Read More

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http://doi.wiley.com/10.1002/jcu.22658
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http://dx.doi.org/10.1002/jcu.22658DOI Listing
February 2019
11 Reads

Melanotic Neuroectodermal Tumor of Infancy: Case Report and Review of Management.

J Oral Maxillofac Surg 2019 Feb 5;77(2):315-320. Epub 2018 Oct 5.

Professor and Vice Chairman, Department of Oral and Maxillofacial Surgery, University of Maryland School of Dentistry, Baltimore, MD.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented tumor of the head and neck, which most commonly presents during the first year of life. Most cases present in the bones of the craniofacial region, including the maxilla (60.3%), skull (18. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391183110
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http://dx.doi.org/10.1016/j.joms.2018.09.033DOI Listing
February 2019
13 Reads

Melanotic neuroectodermal tumor of infancy of the jaw bones: Update on the factors influencing survival and recurrence.

Head Neck 2018 Dec 2;40(12):2749-2756. Epub 2018 Nov 2.

Oral Surgery and Pathology Department, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil.

The aim of the present study was to integrate the available data published on melanotic neuroectodermal tumor of infancy (MNTI) of the jaw bones. An electronic search was undertaken in April 2018. Hundred forty-seven publications and 371 patients were included. Read More

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http://doi.wiley.com/10.1002/hed.25514
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http://dx.doi.org/10.1002/hed.25514DOI Listing
December 2018
7 Reads

Novel therapeutic compound acridine-retrotuftsin action on biological forms of melanoma and neuroblastoma.

J Cancer Res Clin Oncol 2019 Jan 26;145(1):165-179. Epub 2018 Oct 26.

Department of Organic Chemistry, Gdansk University of Technology, Narutowicza St 11/12, 80-233, Gdansk, PL, Poland.

Purpose: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO)-Pro-Lys-Thr-OCH]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies. Thus, we analyzed the action of ART on pairs of biological forms of melanoma (amelanotic and melanotic) and neuroblastoma (dopaminergic and cholinergic) with regard to proliferation, mechanism of cell death, and effect on the activity of tricarboxylic acid cycle (TAC) enzymes. Read More

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http://link.springer.com/10.1007/s00432-018-2776-4
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http://dx.doi.org/10.1007/s00432-018-2776-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326014PMC
January 2019
6 Reads

Melanotic neuroectodermal tumor of infancy: A rare pediatric head and neck lesion.

Pediatr Dermatol 2018 Nov 4;35(6):e389-e390. Epub 2018 Sep 4.

Department of Dermatology, University of New Mexico, Albuquerque, New Mexico.

Melanotic neuroectodermal tumors of infancy are rare tumors arising from the neural crest and typically present during the first 12 months of life. The majority involve the facial bones, although melanotic neuroectodermal tumors of infancy of the skull and extremities have been observed with less frequency, as in the present case. This entity may initially be presented to the dermatologist as a scalp mass and should be considered in the differential diagnosis of infants with rapidly growing head and neck lesions. Read More

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http://doi.wiley.com/10.1111/pde.13601
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http://dx.doi.org/10.1111/pde.13601DOI Listing
November 2018
13 Reads

Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy.

J Oral Maxillofac Pathol 2018 May-Aug;22(2):260-262

Department of Surgical and Hospital Dentistry, University of Louisville School of Dentistry, Louisville, Kentucky, USA.

While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_161_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097382PMC

Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens.

Oral Dis 2018 Nov 10;24(8):1484-1491. Epub 2018 Jul 10.

Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Objectives: To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa.

Materials And Methods: A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of any pigmented lesion were retrieved. Read More

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http://dx.doi.org/10.1111/odi.12924DOI Listing
November 2018
4 Reads

Use of Technological Aids in the Resection of a Rare Maxillofacial Tumor of Infancy.

Cleft Palate Craniofac J 2018 Oct 30;55(9):1308-1312. Epub 2018 May 30.

2 Dell Children's Medical Center, Dell Medical School, University of Texas at Austin, Austin, TX, USA.

Melanotic neuroectodermal tumor of infancy is a rare maxillofacial tumor, usually presenting within the first year of life, often a benign locally aggressive lesion, with wide local excision providing the best opportunity of cure. In past reports, direct tissue visualization guided resection, with occasional need for reoperation to clear margins. In this case report, a method is presented to achieve clear margins in surgery using virtual surgical planning and surgical stealth navigation. Read More

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http://dx.doi.org/10.1177/1055665618763375DOI Listing
October 2018
5 Reads

Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla.

Einstein (Sao Paulo) 2018 May 14;16(2):eRC4025. Epub 2018 May 14.

Universidade Estadual da Paraíba, Campina Grande, PB, Brazil.

Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. Read More

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http://dx.doi.org/10.1590/S1679-45082018RC4025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998940PMC
May 2018
2 Reads

Spontaneous Regression of Diffuse Periosteal Melanotic Neuroectodermal Tumor of Infancy in the Tibia, With 13-Year Follow-up.

J Pediatr Hematol Oncol 2018 Apr 4. Epub 2018 Apr 4.

Departments of Pathology, Radiology, and Pediatric Hematology-Oncology, Loma Linda University Health, Loma Linda, CA.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare entity primarily affecting the craniofacial bones during the first year of life, with only 5 reported cases involving peripheral long bones. We herein present a case of MNTI in the tibia of an infant, with a somewhat atypical presentation, and a noteworthy clinical course characterized by progressive spontaneous resolution without therapy, thus sparing the child the trauma of amputation. There is no evidence of active residual or recurrent disease with 13-year follow-up. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001130DOI Listing
April 2018
4 Reads

Melanotic neuroectodermal tumor of infancy: A rare case report.

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S44-S47

Department of Histopathology, National Reference Labrotory, Dr Lal Path Labs Ltd, New Delhi, India.

Melanotic neuroectodermal tumor of infancy is a rare benign but locally aggressive neoplasm of neural crest origin with a high recurrence rate. It usually affects infants of < 1 year of age. Involvement of maxilla of an infant is the most common presentation although cases outside this setting have been reported. Read More

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http://www.jomfp.in/text.asp?2018/22/4/44/224616
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http://dx.doi.org/10.4103/jomfp.JOMFP_197_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824516PMC
January 2018
10 Reads

Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: A French multicenter study.

J Craniomaxillofac Surg 2018 Feb 12;46(2):201-206. Epub 2017 Dec 12.

Department of Maxillofacial and Plastic Surgery, Hôpital Universitaire Necker-Enfants Malades, 75015, Paris, France; Université Paris Descartes, 75006, Paris, France; Laboratory for Oral and Molecular Pathology, INSERM, UMRS 1138, Centre de Recherche des Cordeliers, 75006, Paris, France. Electronic address:

Objectives: Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck is a rare entity with uncertain clinical behavior. Radical surgical resection is the current recommended treatment, however this can cause severe aesthetic and functional sequelae. The aim of this study was to clinically characterize MNTIs and to stratify risk factors that may influence locoregional recurrence. Read More

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http://dx.doi.org/10.1016/j.jcms.2017.12.001DOI Listing
February 2018
17 Reads
2.600 Impact Factor

A Simplified Overview of World Health Organization Classification Update of Central Nervous System Tumors 2016.

J Neurosci Rural Pract 2017 Oct-Dec;8(4):629-641

Department of Pathology and Emergency Laboratory, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India.

After 8 years, an update of central nervous system (CNS) tumors was published in 2016 after 2007. First time ever, molecular markers along with histology have been used in classification of any tumor. Major changes are seen in glioma and medulloblastoma groups. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_168_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709890PMC
December 2017
15 Reads

Melanotic Neuroectodermal Tumor of Infancy of the Upper Arm.

Med Princ Pract 2017 27;26(6):582-585. Epub 2017 Nov 27.

Objective: To present a case of a 6-month-old infant with melanotic neuroectodermal tumor of infancy (MNTI) in the upper arm.

Clinical Presentation And Intervention: A 6-month-old female presented with a well-circumscribed lesion of the upper arm at the Children's Hospital Zagreb. A biopsy was performed and microscopy revealed 2 cell populations consisting of small neuroblastic cells and larger melanin-containing epithelial cells. Read More

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https://www.karger.com/Article/FullText/485744
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http://dx.doi.org/10.1159/000485744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848479PMC
October 2018
11 Reads

Melanotic neuroectodermal tumor of infancy: a rare presentation of an extremely rare neoplasm and diagnostic implications in Gombe, Nigeria.

Pan Afr Med J 2017 4;28. Epub 2017 Sep 4.

Department of Preventive Dentistry, Bayero University Kano, Nigeria.

Melanotic neuro-ectodermal tumor of infancy is very rare. A unique neoplasm of the formative years, it typically involves the face or cranium; possesses rapid, expansile growth; presents as a firm swelling and displays a high rate of recurrence. Its rarity and unique features make diagnosis and management quite challenging. Read More

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http://dx.doi.org/10.11604/pamj.2017.28.5.9394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681010PMC
December 2017
3 Reads

Melanotic neuroectodermal tumour of infancy: A case report and differential diagnosis.

Neuroradiol J 2018 Aug 10;31(4):434-439. Epub 2017 Nov 10.

4 Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, UK.

Melanotic neuroectodermal tumour of infancy is an uncommon pigmented neoplasm of neural crest origin. It was first described in 1918 by Krompecher, known as congenital melanocarcinoma at that time. Although it is generally agreed upon that it is a benign entity, it is locally aggressive and has a significant recurrent risk, reported to be between 10-15%. Read More

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http://dx.doi.org/10.1177/1971400917741770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111430PMC
August 2018
7 Reads

Melanotic neuroectodermal tumour of infancy: An enigmatic tumour with unique cytomorphological features.

Cytopathology 2018 02 13;29(1):104-108. Epub 2017 Oct 13.

Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/cyt.12483DOI Listing
February 2018

Prenatal Diagnosis of a Melanotic Neuroectodermal Tumor of Infancy (MNTI): A Case Report With a Favorable Outcome After Chemotherapy Failure and Incomplete Resection.

J Pediatr Hematol Oncol 2018 May;40(4):320-324

Unit of Plastic and Maxillofacial Surgery.

We present the case of a woman referred to our department at 34 weeks of pregnancy with a fetal ultrasonographic scan showing a mass that had developed within the right maxilla with invasion of the orbit. A retrospective examination showed that this tumor had been present since the 12th week of pregnancy. At 39+4 weeks of gestation, a boy was born. Read More

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http://dx.doi.org/10.1097/MPH.0000000000000982DOI Listing
May 2018
18 Reads

Melanotic Neuroectodermal Tumor of Infancy in the Maxilla.

J Craniofac Surg 2018 Jan;29(1):e28-e30

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir, Turkey.

Melanotic neuroectodermal tumor of infancy is uncommon and has rapid expansile growth. Melanotic neuroectodermal tumor of infancy is a very rare and benign but locally aggressive neoplasm that originates from neural crest and is composed of relatively primitive pigment-producing cells. The lesion commonly affects the maxilla of infants during the first year of life. Read More

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http://dx.doi.org/10.1097/SCS.0000000000003993DOI Listing
January 2018
2 Reads

Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review.

Pediatr Dev Pathol 2017 Sep-Oct;20(5):411-415. Epub 2017 Jan 25.

1 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.

Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity and rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month-old male, presented with a history of worsening left hemiscrotal swelling for 1 week. Read More

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http://dx.doi.org/10.1177/1093526616686437DOI Listing
January 2017
8 Reads

Primary leptomeningeal primitive neuroectodermal tumor: A difficult entity to diagnose.

Indian J Pathol Microbiol 2017 Apr-Jun;60(2):247-249

Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

A 25-year-old male presented with difficulty in walking, loss of vision, and seizures. A clinical possibility of craniospinal meningeal pathology was considered. On computed tomography (CT) scan and magnetic resonance imaging, there was an enhancement of leptomeninges with few ring-enhancing lesions in both frontal lobes and right frontoparietal region. Read More

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http://dx.doi.org/10.4103/0377-4929.208376DOI Listing
February 2018
2 Reads

Asymptomatic Pigmented Lesions of the Gingiva.

JAMA Dermatol 2017 10;153(10):1045-1046

Section of Oral and Maxillofacial Pathology, Division of Dermatopathology, Department of Dermatology, University of Pennsylvania Health System, Philadelphia.

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2017.1614DOI Listing
October 2017
1 Read

Anaesthetic Management of a Neuroectodermal Tumor of Infancy: A Rare Case Report.

Anesth Essays Res 2017 Jan-Mar;11(1):251-253

Department of Anaesthesiology, TNMC and BYL Nair Hospital, Mumbai, Maharashtra, India.

Melanotic neuroectodermal tumor of infancy is a relatively uncommon osteolytic-pigmented neoplasm that primarily affects the jaws of infants. We report a 5-month-old male child who presented with a swelling in the right upper tooth region of upper jaw in which we face difficult mask ventilation as well as difficult intubation. Wide surgical excision was performed under general anesthesia. Read More

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http://dx.doi.org/10.4103/0259-1162.186863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341631PMC
March 2017
2 Reads

Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: report of a malignant case.

J Neurosurg Pediatr 2017 May 24;19(5):538-545. Epub 2017 Feb 24.

Departments of 1 Paediatric Neurosurgery.

Melanotic neuroectodermal tumor of infancy is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, growing rapidly and developing during the 1st year of life. It most commonly arises from the maxilla, cranial vault, and mandible. Occasionally, it exhibits malignant behavior with local lymph nodes involvement. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/19/5/ar
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http://dx.doi.org/10.3171/2016.11.PEDS16509DOI Listing
May 2017
24 Reads

Melanotic neuroectodermal tumor of infancy: Cytology and histopathology of a rare lesion at an uncommon site.

Diagn Cytopathol 2016 Nov 7. Epub 2016 Nov 7.

Department of Pathology and Surgery Dayanand Medical, College and Hospital Ludhiana, Ludhiana, Punjab, India.

Melanotic neuroectodermal tumour of infancy is a rare, pigmented neoplasm generally arising in infants during the first year of life. The cytological features are rarely described in the literature. This case due to its rarity and unusual site emphasising the cytopathological features and the necessity of histology for differentiating it from other round cell tumours has been presented. Read More

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http://dx.doi.org/10.1002/dc.23624DOI Listing
November 2016
9 Reads

Melanotic neuroectodermal tumour of infancy presenting as an undifferentiated round cell tumour in the soft tissue of the forearm.

Pathology 2017 Jan 1;49(1):87-90. Epub 2016 Dec 1.

Department of Pathology, Ghent University and Ghent University Hospital, Ghent, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025164039
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http://dx.doi.org/10.1016/j.pathol.2016.10.006DOI Listing
January 2017
4 Reads

Melanotic Neuroectodermal Tumor of Infancy with Involvement of the Superior Sagittal Sinus.

Pediatr Neurosurg 2017 6;52(1):36-40. Epub 2016 Sep 6.

Departments of Radiology and Neurosurgery, Le Bonheur Children's Hospital, Memphis, Tenn., USA.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare lesion that typically manifests in the first year of life, most commonly involving the facial bones. We present 2 infants with MNTI involving the posterior skull with associated compression of the superior sagittal sinus (SSS). A review of the anatomical locations of MNTI is offered, and the implications of SSS involvement are described. Read More

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http://dx.doi.org/10.1159/000445954DOI Listing
March 2017
3 Reads

Primary Melanotic Schwannoma with Typical Histology.

J Coll Physicians Surg Pak 2016 Aug;26(8):707-9

Department of Surgery, The Aga Khan University Hospital, Karachi.

We present a case of a 17-year male with a soft tissue density spreading from the neural foramina (T3) of the spinal cord and involving the right upper thoracic cavity. We managed the patient through surgical intervention and resected the complete tumor. Gross definition and microscopic findings of the resected tissue revealed the definitive diagnosis of melanotic schwannoma. Read More

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http://dx.doi.org/2411DOI Listing
August 2016
3 Reads
0.320 Impact Factor

A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.

BMC Cancer 2016 08 12;16:629. Epub 2016 Aug 12.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7HE, UK.

Background: Melanotic neuroectodermal tumor of infancy (MNTI) is exceptionally rare and occurs predominantly in the head and neck (92.8 % cases). The patient reported here is only the eighth case of MNTI presenting in an extremity, and the first reported in the fibula. Read More

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http://dx.doi.org/10.1186/s12885-016-2669-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983003PMC
August 2016
10 Reads
2 Citations
3.362 Impact Factor

Salivary gland anlage tumor.

Indian J Pathol Microbiol 2016 Jul-Sep;59(3):431-3

Department of Pathology, Max Super Speciality Hospital, New Delhi, India.

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http://dx.doi.org/10.4103/0377-4929.188147DOI Listing
March 2017
7 Reads

Salivary gland anlage tumor in a neonate.

Indian J Pathol Microbiol 2016 Jul-Sep;59(3):273

Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.

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http://dx.doi.org/10.4103/0377-4929.188116DOI Listing
March 2017
3 Reads

Melanotic Neuroectodermal Tumor of Infancy.

J Clin Diagn Res 2016 Jun 1;10(6):ZJ07-8. Epub 2016 Jun 1.

Professor and Head, Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences , New Delhi, India .

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http://dx.doi.org/10.7860/JCDR/2016/18206.8009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963796PMC
June 2016
17 Reads

Neurogenic tumors and tumor-like lesions of the oral and maxillofacial region: A clinicopathological study.

Saudi Dent J 2016 Apr 10;28(2):76-9. Epub 2016 Feb 10.

Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

Objective: Oral and maxillofacial lesions of neural origin are rare soft tissue neoplasms. The aim of the present study is to review the epidemiological data of oral and maxillofacial neurogenic lesions submitted for diagnosis to our laboratory over a 31-year period (August 1984-March 2015).

Materials And Methods: The available formalin-fixed embedded specimens, Hematoxylin and Eosin slides, demographic and clinical data were retrieved. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10139052160000
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http://dx.doi.org/10.1016/j.sdentj.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957538PMC
April 2016
6 Reads

Pitfalls and uncertain prognosis in pathological diagnosis of psammomatous melanotic schwannoma.

J Clin Neurosci 2016 Nov 25;33:236-239. Epub 2016 Jul 25.

Department of Pathology and Laboratory Medicine, University of Toronto, 27 King's College Cir, Toronto, ON M5S 1A1, Canada; Li Ka Shing Knowledge Institute, Toronto, ON, Canada; Department of Laboratory Medicine, St. Michael's Hospital, Toronto, ON, Canada. Electronic address:

A 20-year-old woman presenting with a pelvic mass identified as a psammomatous melanotic schwannoma (PMS) with atypical histological features was later found to have family history of cardiac myxomas consistent with Carney's complex. The BRAF V600E mutation was absent in the tumor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868163039
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http://dx.doi.org/10.1016/j.jocn.2016.05.020DOI Listing
November 2016
3 Reads

Metastatic Melanotic Neuroectodermal Tumor of Infancy: Report of a Case and Review of the Literature.

J Oral Maxillofac Surg 2016 Dec 12;74(12):2431-2440. Epub 2016 Jun 12.

Professor and Chair, Department of Oral and Maxillofacial Surgery, LSU Health Sciences University, Shreveport, LA.

Melanotic neuroectodermal tumors of infancy (MNTI) are rapidly growing pigmented tumors that occur predominantly within bony head and neck structures. There are fewer than 400 cases reported in the literature with the majority affecting the maxilla. Locations in other intraosseous and extraosseous structures have been characterized, including the mandible (6% of MNTIs). Read More

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http://dx.doi.org/10.1016/j.joms.2016.05.028DOI Listing
December 2016
4 Reads

Mandibular melanotic neuroectodermal tumor of infancy: a role for neoadjuvant chemotherapy.

Eur Arch Otorhinolaryngol 2016 Dec 23;273(12):4629-4635. Epub 2016 Apr 23.

Department of Otolaryngology Head and Neck Surgery, American University of Beirut Medical Center, 6th Floor, Hamra, Beirut, 1107 2020, Lebanon.

Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a rare, locally aggressive neoplasm with a predilection for the head and neck area, most commonly occurring in the maxilla. The vast majority of treatment modalities for all cases of MNTI to date have involved surgical intervention only, with just 9.6 % involving some sort of chemotherapy, radiotherapy, or a combination of the prior mentioned modalities. Read More

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http://dx.doi.org/10.1007/s00405-016-4066-6DOI Listing
December 2016
5 Reads

Melanotic neuroectodermal tumor of infancy.

J Clin Neurosci 2016 Sep 16;31:205-7. Epub 2016 Apr 16.

Department of Diagnostic Radiology, Yale School of Medicine, BOX 208042, Tompkins East 2, 333 Cedar Street, New Haven, CT 06520-8042, USA. Electronic address:

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented craniofacial tumor of newborns and infants. We report the imaging findings of a 3-month old male patient with a maxillary MNTI. Detailed discussion on imaging features on various magnetic resonance sequences and CT scan are included. Read More

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http://medind.nic.in/cab/t12/i1/cabt12i1p108.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S096758681600146
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http://dx.doi.org/10.1016/j.jocn.2016.02.023DOI Listing
September 2016
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Reconstruction of anterior maxillary defect with buccal pad fat after excision of melanotic neuroectodermal tumor of infancy.

Ann Maxillofac Surg 2015 Jul-Dec;5(2):234-6

Unit of Oral and Maxillofacial Surgery, Oral Health Sciences Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

This paper highlights a rare case of melanotic neuroectodermal tumor of infancy involving the anterior maxilla in a 3-month-old infant. The tumor was excised completely, and the defect was reconstructed with a bilateral buccal pad of fat. The patient has been followed for 2 years without any evidence of recurrence. Read More

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http://dx.doi.org/10.4103/2231-0746.175773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772568PMC
March 2016
10 Reads

Melanotic schwannoma of the L5 root.

Neuroradiol J 2016 Jun 11;29(3):219-21. Epub 2016 Mar 11.

Pathology Department, Bahçeşehir University, İstanbul, Turkey.

Melanotic neoplasm of the central nervous system is rare and the majority of them are metastatic. Melanotic schwannoma (MS) is an unusual variant of nerve sheath neoplasm accounting for less than 1% of primary nerve sheath tumors. A case involving a 36-year-old man with MS at the L5 root is presented. Read More

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http://dx.doi.org/10.1177/1971400916638359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977922PMC
June 2016
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Melanotic Neuroectodermal Tumor of Infancy in the Epididymis: A Brief Report and Review of the Role of Chemotherapy in Management.

J Pediatr Hematol Oncol 2016 Apr;38(3):e144-6

*St Joseph's Children's Hospital, Paterson, NJ †Rady Children's Hospital-San Diego, San Diego, CA.

Melanotic neuroectodermal tumor of infancy is a rare benign tumor of neural crest origin. The tumor generally presents in the jawbones; however, it occasionally occurs in extracranial sites. Although 95% of these tumors present within the first year of life and 15% in extracranial locations, we report an unusual case of a 15-month-old male with melanotic neuroectodermal tumor of infancy of the epididymis. Read More

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http://dx.doi.org/10.1097/MPH.0000000000000511DOI Listing
April 2016
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Melanotic neuroectodermal tumor of infancy in the soft tissue of the forearm: report of a case.

Int J Clin Exp Pathol 2015 1;8(10):13584-9. Epub 2015 Oct 1.

Department of Pathology, Children's Hospital of Fudan University Shanghai, China.

Melanotic neuroectodermal tumor of infancy is rare. Only 3 cases have been reported in the soft tissue of the extremities up to date. It has a typically biphasic feature in morphology. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680524PMC
October 2016
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Obturator Prostheses for Melanotic Neuroectodermal Tumor of Infancy in the Maxilla.

J Craniofac Surg 2016 Jan;27(1):e64-5

*Dental Oncology Service, Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo †Oral Diagnosis Department, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.

Melanotic neuroectodermal tumor of infancy frequently affects the maxilla. A communication between the oral and nasal cavities can be created by surgery. The authors rehabilitated a young patient with obturator prostheses to correct feeding. Read More

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http://dx.doi.org/10.1097/SCS.0000000000002228DOI Listing
January 2016
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Melanotic neuroectodermal tumor of infancy in the skull: a case report.

Turk J Pediatr 2015 Mar-Apr;57(2):183-5

Department of Neurosurgery , Pamukkale University Faculty of Medicine, Private Denizli Surgery Hospital, Denizli, Turkey.

Melanotic neuroectodermal tumor of infancy (MNTI) is a rarely occurring neoplasm of neural crest origin, appearing in children during the first year of life. MNTI is a benign tumor but is nonetheless locally aggressive; it usually originates from the maxilla and the mandible. Recognition of the diagnostic features of MNTI is important, so that it may be differentiated from benign lesions (dermoid or epidermoid cysts, vascular lesions) as well as from malignant lesions such as small round cell tumors. Read More

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http://www.scielo.br/pdf/anp/v63n3a/a22v633a.pdf
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http://www.ajnr.org/content/16/6/1273.full.pdf
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August 2016
3 Reads

Protumorigenic M2-like phenotype cell infiltration in the melanotic neuroectodermal tumor of infancy.

Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Feb 10;121(2):173-9. Epub 2015 Dec 10.

Professor of Stomatology, Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, UNESP-Univ Estadual Paulista, School of Dentistry, São José dos Campos, Brazil. Electronic address:

Objective: The aim of this study is to report 2 cases of melanotic neuroectodermal tumor of infancy (MNTI), emphasizing the analysis of intratumoral immune cells by immunohistochemistry.

Study Design: Case 1: A 6-month-old girl presented with a 3-cm tumor in the anterior region of the left maxilla. Case 2: A 4-month-old boy presented with a 4-cm tumor in the anterior region of the left maxilla. Read More

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http://dx.doi.org/10.1016/j.oooo.2015.09.015DOI Listing
February 2016
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Melanotic Neuroectodermal Tumor of Infancy Presenting with Fast Growing Scrotal Swelling: A Case Report and Literature Review.

Pediatr Dev Pathol 2015 Dec 15. Epub 2015 Dec 15.

6 Children's Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, Calif Pathology and Laboratory Medicine.

Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity, rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month old male, presented with a history of worsening left hemiscrotal swelling for one week. Read More

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http://dx.doi.org/10.2350/15-10-1715-CR.1DOI Listing
December 2015
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Clinicopathological features of melanotic neuroectodermal tumor of infancy: Report of two cases.

Auris Nasus Larynx 2016 Aug 18;43(4):451-4. Epub 2015 Nov 18.

Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Melanotic neuroectodermal tumor of infancy (MNTI) is an extremely rare, pigmented neoplastic entity of neural crest origin. Histological and immunohistochemical profiles indicate the presence of two components, small rounded neuroblast-like cellular areas and areas with large melanin-containing cells which consist of combination of neural, melanocytic, and epithelial cell types. Here we present two interesting cases of infants with MNTI which have different clinicopathological features. Read More

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http://dx.doi.org/10.1016/j.anl.2015.10.010DOI Listing
August 2016
17 Reads

Extensive Melanotic Neuroectodermal Tumor of Infancy.

Head Neck Pathol 2016 Sep 18;10(3):349-53. Epub 2015 Nov 18.

Department of Head and Neck Surgery, Albert Sabin Hospital of Fortaleza, Fortaleza, Ceará, Brazil.

The melanotic neuroectodermal tumor of infancy (MNTI) is a rare childhood neoplasm with an alarming but classical clinical presentation. We present the case of a 2-month-old male infant treated with surgery for an aggressive MNTI on the alveolar process of the maxilla. Radiographic examination showed a diffuse osteolytic radiolucent lesion in the right maxilla, and displacement and dysmorphic changes in the developing primary tooth buds. Read More

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http://dx.doi.org/10.1007/s12105-015-0671-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972745PMC
September 2016
2 Reads