405 results match your criteria Melanonychia


Hyperpigmented macules in the oral mucosa and melanonychia.

JAAD Case Rep 2018 Nov 16;4(10):1083-1085. Epub 2018 Nov 16.

St. Joseph Mercy Hospital, Ann Arbor, Dermatology Residency Program, Ypsilanti, Michigan.

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November 2018

Onychoscopy: an observational study in 237 patients from the Kashmir Valley of North India.

Dermatol Pract Concept 2018 Oct 31;8(4):283-291. Epub 2018 Oct 31.

Postgraduate Department of Dermatology, STD & Leprosy, Government Medical College, Srinagar, University of Kashmir, Jammu & Kashmir, India.

Background: Nail disorders comprise approximately 10% of all dermatological conditions. Because diagnosis is not always possible by clinical means alone, additional diagnostic procedures may be required at times. Dermoscopy of nails (onychoscopy) has shown promising results in diagnosing various nail disorders and also avoids time-consuming investigations such as culture and biopsy. Read More

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October 2018
2 Reads

[Discolorations of the nail plate - the causes are multiple].

Authors:
Dietrich Abeck

MMW Fortschr Med 2018 Nov;160(20):48-52

Hautzentrum Nymphenburg, Renatastraße 72, D-80639, München, Deutschland.

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November 2018

Longitudinal melanonychia and subungual hemorrhage in a patient with systemic lupus erythematosus treated with hydroxychloroquine.

Lupus 2018 Nov 14:961203318812685. Epub 2018 Nov 14.

Department of Dermatology, Peking University People's Hospital, Beijing, People's Republic of China.

Hydroxychloroquine is an antimalarial agent, most commonly prescribed in the treatment of several rheumatic diseases. Although generally well tolerated, a variety of mucocutaneous adverse effects have been reported. Besides the familiar adverse effects, longitudinal melanonychia is rarely seen. Read More

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November 2018
4 Reads

Isolated Nail Pigmentation Associated with Chikungunya: A Hitherto Unreported Manifestation.

Skin Appendage Disord 2018 Oct 3;4(4):312-314. Epub 2018 Jan 3.

Department of Dermatology, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Chikungunya (CHK) fever is a re-emerging RNA viral infection caused by the bite of infected mosquitoes which presents with a multitude of mucocutaneous manifestations, including a characteristic morbilliform rash, centrofacial pigmentation, aphthae-like lesions, and vesiculobullous lesions sparing mucosae. The majority of these lesions resolve spontaneously and do not require specific therapy. With regular and cyclical outbreaks in many countries for many decades, it is obligatory for dermatologists to be aware of the different skin lesions in the wake of early diagnosis and the need for conservative management. Read More

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October 2018
5 Reads

Pigmented Lesions of the Nail Unit.

Am J Dermatopathol 2018 Nov;40(11):793-804

Faculty in Dermatopathology, Department of Dermatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Pigmented lesions of the nail unit are commonly encountered in the clinical setting. Yet, they often present a unique challenge to clinicians because of a broad differential diagnosis or unfamiliarity with clinical and histopathologic features. A wide variety of causes exist ranging from benign lesions such as subungual hemorrhage to malignant lesions such as subungual melanoma. Read More

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November 2018
2 Reads

Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome.

World J Clin Cases 2018 Sep;6(10):322-334

Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, Jiangsu Province, China.

Labial and oral melanotic macules are commonly encountered in a broad range of conditions ranging from physiologic pigmentation to a sign of an underlying life-threatening disease. Although Laugier-Hunziker syndrome (LHS) shares some features of labial and oral pigmentation with a variety of conditions, it is a benign and acquired condition, frequently associated with longitudinal melanonychia. Herein, the demographic, clinical, dermoscopic, and pathological aspects of LHS were reviewed comprehensively. Read More

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September 2018
2 Reads

Onychoscopy: Dermoscopy of the Nails.

Dermatol Clin 2018 Oct;36(4):431-438

Department of Specialised Experimental and Diagnostic Medicine, Dermatology, Alma Mater Studiorum, Università di Bologna, Bologna, Italy.

Onychoscopy is the examination of the nail unit using a dermoscope. The dermoscopic criteria for a valid diagnosis have been developed and assessed in numerous papers. However, in all nail alterations that are suspicious or potentially malignant, a surgical intervention with subsequent histopathological evaluation should be performed. Read More

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October 2018
5 Reads

[Longitudinal melanonychia as a clinical manisfestation of Addison's disease].

Aten Primaria 2018 Aug 28. Epub 2018 Aug 28.

Servicio de Medicina Interna, Hospital Santos Reyes, Aranda de Duero, Burgos, España.

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A Case of Pigmented Longitudinal Melanonychia.

JAMA Dermatol 2018 Aug 15. Epub 2018 Aug 15.

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas.

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August 2018
1 Read

Ten-year follow up of longitudinal melanonychia in childhood: A case report.

J Dermatol 2018 Aug 20. Epub 2018 Aug 20.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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August 2018
9 Reads

Laugier-Hunziker syndrome in endocrine clinical practice.

Endocrinol Diabetes Metab Case Rep 2018 26;2018. Epub 2018 Jul 26.

Departments of Endocrinology, Diabetes and Metabolic Diseases.

Laugier-Hunziker syndrome (LHS) is a rare, benign and acquired disorder characterized by hyperpigmentation of the oral cavity and lips along with longitudinal melanonychia. No underlying systemic abnormalities or malignant predisposition is associated with it. In everyday clinical practice, an endocrinologist encounters certain endocrine conditions (e. Read More

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July 2018
9 Reads

Subungual Melanoma: A Descriptive Study of 34 Patients.

Actas Dermosifiliogr 2018 Nov 3;109(9):801-806. Epub 2018 Aug 3.

Servicio de Dermatología, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España.

Introduction And Objectives: Subungual melanoma constitutes a diagnostic challenge because it often has an atypical clinical presentation. The aims of this study were to revise the clinical and pathologic characteristics of patients with subungual melanoma diagnosed at a tertiary care university hospital and analyze the factors potentially associated with a delayed diagnosis.

Material And Methods: We analyzed data for 34 patients diagnosed with subungual melanoma at our hospital over a period of 20 years. Read More

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November 2018
2 Reads

Dermoscopy as a first step in the diagnosis of onychomycosis.

Postepy Dermatol Alergol 2018 Jun 18;35(3):251-258. Epub 2018 Jun 18.

Department of Dermatology, Ankara Numune Research and Education Hospital, Ankara, Turkey.

Introduction: Over the years, clinical studies have provided new knowledge about the dermoscopic features of the diseases of cutaneous annexes. It seems that dermoscopy has opened a new morphological dimension in the diagnosis and management of hair disorders and onychopathies.

Aim: To identify and describe dermoscopic features of onychomycosis. Read More

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June 2018
5 Reads

Melanonychia.

QJM 2018 Dec;111(12):909

Department of Internal Medicine, Post-Graduate Institute of Medical Education and Research, Chandigarh, India.

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December 2018

Longitudinal melanonychia in adults and children: a clinical and histopathological review of Korean patients.

Eur J Dermatol 2018 Jun;28(3):400-401

Department of Dermatology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.

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Subungual melanoma complicated by hydroxyurea-induced melanonychia with non-melanoma Hutchinson's sign.

Eur J Dermatol 2018 Aug;28(4):559-561

Department of Dermatology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

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August 2018
6 Reads

Treatment of Digital Melanonychia with Atypia.

Plast Reconstr Surg 2018 08;142(2):439-445

Boston, Mass. From the Department of Orthopedic Surgery and the Division of Plastic Surgery, Hand and Upper Extremity Service, Massachusetts General Hospital, Harvard Medical School.

Background: Melanonychia of the digit is uncommon in the Caucasian population and is concerning because of potential malignant transformation. Several histologic changes occur before malignant transformation, including melanocytic atypia. The authors evaluated patients with melanonychia with melanocytic hyperplasia to determine the risk factors for malignant transformation. Read More

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Assessment of a Predictive Scoring Model for Dermoscopy of Subungual Melanoma In Situ.

JAMA Dermatol 2018 Aug;154(8):890-896

Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Importance: Subungual melanoma in situ (SMIS) is a malignant neoplasm that requires early diagnosis and complete surgical excision; however, little is known about the usefulness of the detailed dermoscopic features of longitudinal melanonychia (LM) to predict the diagnosis of SMIS.

Objectives: To investigate the characteristic dermoscopic findings of SMIS and to establish a predictive scoring model for the diagnosis of SMIS in patients with adult-onset LM affecting a single digit.

Design, Setting, And Participants: A cohort study of 19 patients with biopsy-proven SMIS and 26 patients with benign LM diagnosed in a tertiary referral hospital in Seoul, South Korea, from September 1, 2013, to July 31, 2017. Read More

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August 2018
17 Reads

Topical application of 5-fluorouracil 5 percent cream associated with severe neutropenia: discussion of a case and review of systemic reactions after topical treatment with 5-fluorouracil.

Authors:
Philip R Cohen

Dermatol Online J 2018 Apr 15;24(4). Epub 2018 Apr 15.

Department of Dermatology, University of California San Diego, La Jolla, California.

5-fluorouracil, a fluoropyrimidine antineoplastic drug, is used to topically treat actinic keratoses. Local skin reactions to the medication are common and anticipated. However, severe adverse events from topical 5-fluorouracil are rare and unexpected. Read More

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April 2018
17 Reads

In situ nail unit melanoma: epidemiological and clinic-pathologic features with conservative treatment and long-term follow-up.

J Eur Acad Dermatol Venereol 2018 Dec 27;32(12):2300-2306. Epub 2018 Jun 27.

Dermatology Department, Bichat-Claude Bernard Hospital, Paris, France.

Background: Nail unit melanoma (NUM) is a rare melanoma variant, usually associated with a poor prognosis because of a delayed diagnosis. Few data are available concerning the management and long-term outcome of in situ NUM.

Objective: To use a large cohort to provide comprehensive patient data and long-term follow-up information. Read More

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December 2018
7 Reads

Pigmented squamous cell carcinoma presenting as longitudinal melanonychia in a transplant recipient.

Cutis 2018 May;101(5):375-377

Department of Dermatology, University of Illinois at Chicago, and the Department of Dermatology, Rush University, Chicago, USA.

We report the case of a 62-year-old black man who was on a maintenance immunosuppressive regimen that included mycophenolate mofetil and cyclosporine following renal transplantation 9 years prior. He presented to the dermatology department for evaluation of a pigmented longitudinal streak on the left third finger adjacent to the lateral nail fold that had been present for several months. He noted that the streak was increasing in size, and his fingertip had recently become tender. Read More

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May 2018
1 Read

Longitudinal Melanonychia Biopsy: What Not to Do.

J Drugs Dermatol 2018 May;17(5):587-588

The nail matrix biopsy is an important technique in confirming or excluding a diagnosis of melanoma in a patient with longitudinal melanonychia. Dermatologists are the first-line diagnosticians for these pigmented lesions of the nail unit, however, for different reasons, some are reluctant to perform a nail biopsy. This case demonstrates how a poor biopsy technique resulted in a misdiagnosis in a patient with melanoma in situ. Read More

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May 2018
2 Reads

Drug-induced longitudinal melanonychia and transverse muehrcke's lines.

J Eur Acad Dermatol Venereol 2018 Dec 29;32(12):e462-e463. Epub 2018 May 29.

Department of Dermatology, University of Trieste, Trieste, Italy.

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December 2018
5 Reads

Longitudinal subungual acanthoma: one denomination for various clinical presentations.

J Eur Acad Dermatol Venereol 2018 Sep 7;32(9):1608-1613. Epub 2018 Jun 7.

Dermatology Department, Cancer Institute, Gustave Roussy, Villejuif, France.

Background: Benign subungual proliferation of the distal nail matrix and bed such as longitudinal keratosis, seborrhoeic keratosis or onychocytic matricoma should belong to a single spectrum of diseases.

Objective: This article intends to demonstrate clinically and histologically the different facets of Nail unit longitudinal acanthoma.

Methods: We report three new cases that present as a longitudinal melanonychia with thickening of the nail plate in two of them and as leukoxanthonychia in the third one. Read More

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September 2018
2 Reads

Onychophagia Induced Melanonychia, Splinter Hemorrhages, Leukonychia, and Pterygium Inversum Unguis Concurrently.

Case Rep Dermatol Med 2018 30;2018:3230582. Epub 2018 Jan 30.

Department of Dermatology, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey.

Onychophagia, which refers to compulsive nail-biting behavior, is common among children and young adults. Onychophagia can cause destruction to the cuticle and nail plate, leading to shortening of nails, chronic paronychia, and secondary infections. Relatively uncommon effects include pigmentary changes, such as longitudinal melanonychia and splinter hemorrhages. Read More

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January 2018
10 Reads

Dermoscopic features of onychotillomania: A study of 36 cases.

J Am Acad Dermatol 2018 Oct 14;79(4):702-705. Epub 2018 Apr 14.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Background: Onychotillomania is a nail-picking disorder characterized by nail dystrophy and abnormal morphology of the nail plate, nail bed, and periungual skin.

Objective: The purpose of this study was to describe the dermoscopic features of onychotillomania.

Methods: A retrospective study of the dermoscopy images of 36 patients affected by onychotillomania. Read More

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October 2018
7 Reads

Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy.

F1000Res 2018 6;7:284. Epub 2018 Mar 6.

Department of Dermatology, College of Medicine, King Faisal University, Hofuf, Saudi Arabia.

Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham's striae constituting the hallmark of the condition. Read More

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March 2018
14 Reads

Subungual atypical lentiginous melanocytic proliferations in children and adolescents: A clinicopathologic study.

J Am Acad Dermatol 2018 Aug 27;79(2):327-336.e2. Epub 2018 Mar 27.

Department of Pathology, University of Michigan, Ann Arbor, Michigan; Department of Dermatology, University of Michigan, Ann Arbor, Michigan. Electronic address:

Background: Most subungual melanocytic lesions in children are benign, but some are difficult to classify due to prominent lentiginous growth and high-grade cytologic atypia.

Objective: To characterize the clinicopathologic features of these rare lesions.

Methods: Subungual atypical lentiginous melanocytic proliferations from patients <20 years of age were collected for clinical and histopathologic review. Read More

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August 2018
12 Reads

Longitudinal Melanonychia: Differences in Etiology Are Associated with Patient Age at Diagnosis.

Dermatology 2017 19;233(6):446-455. Epub 2018 Mar 19.

Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: Longitudinal melanonychia (LM) may occur as a result of nail apparatus melanoma. Knowledge of etiology plays an important role in the management of LM.

Objectives: The study is aimed to compare the diagnosis of LM in different age groups. Read More

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October 2018
10 Reads

Cutaneous Adverse Reactions of Chemotherapy in Cancer Patients: A Clinicoepidemiological Study.

Indian J Dermatol 2018 Jan-Feb;63(1):41-46

Department of Dermatology, Venereology and Leprosy, S. P. Medical College, Bikaner, Rajasthan, India.

Background: The diagnosis of cutaneous adversities in the cancer patient is especially difficult, given the complexity of their illness and combination protocols used for the treatment. The present study was undertaken to know the spectrum of cutaneous adversities in patients undergoing chemotherapy and the drug(s) most commonly associated with it.

Materials And Methods: A total of 1000 patients with malignancies under chemotherapy in the oncology ward and outpatient department were screened in this observational study from January 2013 to February 2015. Read More

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March 2018
4 Reads

A pediatric case of unusual melanocytic proliferation of the nail.

Dermatol Online J 2017 Jul 15;23(7). Epub 2017 Jul 15.

New York Medical College, Valhalla, New York.

Pigmentation of the nail plate, or melanonychia, is typically a benign condition caused by melanocyte activation. Although rare, melanonychia may be the initial presentation of melanoma, thus all cases require an in-depth examination. Evaluation in pediatric patients can prove especially difficult as benign cases have a higher prevalence of atypia compared to adults. Read More

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July 2017
2 Reads

Early Detection of Subungual Melanoma : Proposal of ABCD Strategy in Clinical Practice Based on Case Series.

Ann Dermatol 2018 Feb 26;30(1):36-40. Epub 2017 Dec 26.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival.

Objective: We sought to establish screening strategy for SUM .

Methods: We retrospectively reviewed medical records of 8 patients pathologically diagnosed as SUM between January 2015 and September 2016. Read More

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February 2018
12 Reads

Multiple melanonychia striata as a sign of connective tissue disorders.

J Am Acad Dermatol 2018 Aug 12;79(2):375-377. Epub 2018 Jan 12.

Department of Dermatology, Shinshu University School of Medicine, Nagano, Japan.

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August 2018
6 Reads

Congenital longitudinal melanonychia: a case report.

Acta Dermatovenerol Alp Pannonica Adriat 2017 Dec;26(4):119-120

Department of Dermatology, University Medical Centre, Maribor, Slovenia.

Congenital longitudinal melanonychia is rarely seen in Caucasians and poses a diagnostic dilemma. It is characterized by the presence of hyperpigmented brown or black streaks visible in the nail plate. We present the case of 20-month-old boy with congenital longitudinal melanonychia, the diagnostic procedure, and management. Read More

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December 2017
5 Reads

Laugier-Hunziker syndrome: A case report.

J Stomatol Oral Maxillofac Surg 2018 Apr 12;119(2):158-160. Epub 2017 Dec 12.

Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, 210008 Nanjing, China. Electronic address:

Laugier-Hunziker syndrome (LHS) is a rare, benign, acquired pigmentary condition mainly affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. Herein, we reported a 45-year-old female case with LHS. The clinical, dermoscopic, histopathologic features of LHS were reviewed and the important differential diagnosis was discussed. Read More

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April 2018
3 Reads

Multiple digit melanonychia: Examine the scalp.

J Am Acad Dermatol 2018 05 5;78(5):e97-e98. Epub 2017 Dec 5.

Dermatology Unit, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

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May 2018
12 Reads

Melanonychia induced by venlafaxine hydrochloride.

G Ital Dermatol Venereol 2017 Nov 30. Epub 2017 Nov 30.

Unit of Dermatology and Cosmetology, IRCCS University Vita-Salute San Raffaele, Milan, Italy.

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November 2017
9 Reads

A Novel Window Technique Using CO2 Laser, and a Review of Methods for Nail Matrix Biopsy of Longitudinal Melanonychia.

Dermatol Surg 2018 May;44(5):651-660

Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Background: Nail matrix histopathological examination is essential to diagnose longitudinal melanonychia (LM). Several methods for nail matrix biopsy have been introduced but are often difficult to perform because of their invasiveness and technical difficulty. Therefore, a less invasive and novel biopsy technique is needed. Read More

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May 2018
20 Reads

Clinicopathologic features of 28 cases of nail matrix nevi (NMNs) in Asians: Comparison between children and adults.

J Am Acad Dermatol 2018 03 26;78(3):479-489. Epub 2017 Oct 26.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Background: Clinical distinction between nail matrix nevus (NMN) and subungual melanoma (SUM) can be challenging. More precise delineation of the clinicodermoscopic characteristics specific for NMNs is needed.

Objective: We sought to analyze the clinicopathologic features of childhood and adult NMNs and to propose clinicodermoscopic features that can aid in differentiating NMNs from SUM. Read More

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March 2018
7 Reads

Longitudinal melanonychia due to voriconazole therapy during treatment of chromoblastomycosis.

Clin Exp Dermatol 2018 Jan 13;43(1):75-76. Epub 2017 Oct 13.

Department of Dermatology, Division of Dermatology of Hospital das Clínicas, São Paulo University, School of Medicine, Sao Paulo, Brazil.

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January 2018
5 Reads

Submitting tangential nail-matrix specimens.

J Am Acad Dermatol 2017 11;77(5):e133-e134

Dermatology Department, Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.

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November 2017
10 Reads

"Dots and lines": A melanonychia striata in regression: Report of a case.

Pediatr Dermatol 2017 Nov 2;34(6):e321-e323. Epub 2017 Oct 2.

Department of Dermatology, Maastricht Universitair Medisch Centrum, Maastricht, The Netherlands.

A 2-year-old Caucasian boy with melanonychia striata with multiple striking pits on the nail plate of one fingernail is described. Nail disorders often pose diagnostic and therapeutic challenges for clinicians, especially melanonychia striata, because of the fear of a subungual melanoma. Only a few childhood cases of melanonychia striata have been described, and the multiple pits are even less common. Read More

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November 2017
8 Reads

A Case of Subungual Melanoma in an 18-Year-Old Girl Presented with Total Melanonychia.

Ann Dermatol 2017 Oct 25;29(5):653-654. Epub 2017 Aug 25.

Department of Dermatology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.

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October 2017
5 Reads

Distinct Patterns and Aetiology of Chromonychia.

Acta Derm Venereol 2018 Jan;98(1):108-113

Department of Dermatology, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 61469, Korea.

Abnormal colouring of the nails may be a sign of underlying systemic or local disorders. This study investigated the prevalence and causes of chromonychia as a whole, as well as of each subtype. Among 163 patients with chromonychia, trauma was the pathogenesis in up to 20. Read More

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January 2018
3 Reads

Pediatric longitudinal melanonychia.

CMAJ 2017 08;189(34):E1093

Departments of Dermatology and Skin Science (Burleigh), Pediatrics (Lam) and Dermatology (Lam), Faculty of Medicine, The University of British Columbia, Vancouver, BC.

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August 2017
5 Reads

Twenty-Nail Transverse Melanonychia Induced by Hydroxyurea: Case Report and Review of the Literature.

J Drugs Dermatol 2017 Aug;16(8):814-815

Twenty-nail transverse melanonychia from hydroxyurea is a rare phenomenon, only reported four times previously. Here we describe a 51-year-old female who presented with 20-nail transverse melanonychia 3 months after initiating hydroxyurea therapy. Transverse melanonychia is a benign process but can cause patients significant distress, and thus is an entity with which dermatologists should recognize. Read More

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August 2017
13 Reads

Spontaneous Regression of a Nail Matrix Melanocytic Nevus in a Child.

Pediatr Dermatol 2017 Sep 14;34(5):e254-e256. Epub 2017 Aug 14.

Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida.

A 14-year-old Hispanic boy presented with a 0.25-mm wide, sharply demarcated, dark brown band of longitudinal melanonychia of the left thumbnail. A clinical diagnosis of nail matrix nevus was made and the boy was scheduled for follow-up. Read More

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September 2017
5 Reads

Transverse melanonychia and palmar hyperpigmentation secondary to hydroxyurea therapy.

Cutis 2017 05;99(5):E2-E4

Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

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May 2017
6 Reads