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    343 results match your criteria Melanonychia

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    Onychomatricoma: A Case Report with 5-year Follow-up.
    J Cutan Aesthet Surg 2016 Oct-Dec;9(4):270-273
    Sector of Dermatology, School of Medicine, University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    The authors present a case of onychomatricoma, a rare benign tumour of the nail matrix, first described by Baran and Kint in 1992. The lesion appeared on the proximal nail fold, covering half the nail of the second left finger. The nail was thickened and yellowish with longitudinal melanonychia. Read More

    Nail apparatus melanoma thickness is associated with side and age.
    Br J Dermatol 2017 Jan 24. Epub 2017 Jan 24.
    Department of Dermatology, Shinshu University School of Medicine.
    Nail apparatus melanoma (NAM) is a rare variant of cutaneous melanoma that arises in the nail unit and typically appears as melanonychia in its early stage.(1) Since the factors associated with the progression of NAM are not fully understood, 102 cases of NAM were analysed to identify clinical factors associated with Breslow's thickness. This article is protected by copyright. Read More

    Nail disorders: Kids are not just little people.
    Clin Dermatol 2016 Nov - Dec;34(6):736-741. Epub 2016 Jul 11.
    Department of Dermatology, Weill Cornell Medical College, New York, NY. Electronic address:
    Nail disorders comprise an important subset of dermatologic conditions and often pose both diagnostic and therapeutic challenges to the clinician. Presentation and management can differ in adults and children. Proper understanding of these differences is important in delivering optimal patient care. Read More

    Dermoscopic patterns of fungal melanonychia: A comparative study with other causes of melanonychia.
    J Am Acad Dermatol 2017 Mar 25;76(3):488-493.e2. Epub 2016 Oct 25.
    Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea; Institute of Human-Environment Interface Biology, Seoul National University, Seoul, Republic of Korea. Electronic address:
    Background: Diagnosing fungal melanonychia (FM) is often difficult because it mimics melanonychia caused by other factors. Dermoscopy is helpful in the setting of nail pigmentation. However, the diagnostic characteristics of FM on dermoscopy are not fully elucidated. Read More

    Routine use of perioperative in vivo reflectance confocal microscopy of the nail matrix in melanonychia striata: about 30 cases.
    Br J Dermatol 2016 Oct 3. Epub 2016 Oct 3.
    Department of Dermatology, Lyon 1 University, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, 69495, Pierre Bénite CEDEX, France.
    in situ or minimally invasive melanoma can be treated by nonamputative wide excision of the nail unit followed by a skin graft, performed by a dermatologic surgeon, with an excellent cosmetic and functional result that does not impair the prognosis.(1-2) We previously published a preliminary study showing a good correlation between perioperative Reflectance Confocal Microscopy (RCM) and histopathology of the nail matrix in case of subungual melanoma (SUM)(3) . Since then, we used perioperative in vivo RCM in our centre, after informed consent of patient, during surgical exploration of 30 consecutive cases of suspicious MS between 1/11/2012 and 31/03/2016. Read More

    Clinical and dermoscopic clues to differentiate pigmented nail bands: an International Dermoscopy Society study.
    J Eur Acad Dermatol Venereol 2016 Oct 1. Epub 2016 Oct 1.
    Dermatology Unit, Second University of Naples, Naples, Italy.
    Background: Longitudinal melanonychia might be difficult to differentiate and the use of dermoscopy can be useful for the preoperative evaluation and management decision.

    Objectives: The aim of our study was to investigate clinical and dermoscopic criteria of acquired longitudinal melanonychia in adults to identify the best predictors of melanoma using a multivariate analysis and to explore eventual new dermoscopic criteria for nail melanoma diagnosis.

    Methods: In this retrospective observational study, 82 histopathologically diagnosed, acquired nail pigmented bands were collected and examined. Read More

    [Laugier-Hunziker syndrome in a patient with Sjögren’s syndrome: Report of one case].
    Rev Med Chil 2016 May;144(5):671-4
    Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patterns, such as Peutz-Jeghers syndrome, adrenal insufficiency and melanoma. We report a 58-year-old female with a 20-year history of Sjögren’s syndrome, presenting with melanonychia and hyperpigmentation in the buccal mucosa. Read More

    Dermoscopic features of nail matrix nevus (NMN) in adults and children: A comparative analysis.
    J Am Acad Dermatol 2016 Sep 11;75(3):535-40. Epub 2016 May 11.
    Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea; Institute of Human-Environment Interface Biology, Seoul National University, Seoul, Korea. Electronic address:
    Background: Nail matrix nevus (NMN) is one cause of longitudinal melanonychia. The typical dermoscopic patterns of NMNs are well established. However, little is known about how the dermoscopic characteristics of NMNs differ between adults and children. Read More

    Evaluation of nail lines: Color and shape hold clues.
    Cleve Clin J Med 2016 May;83(5):385-91
    Clinical Professor of Dermatology, Weill Cornell Medical College, New York, NY, USA.
    Nail lines are a common presenting finding. A thorough inspection of the fingernails and toenails is an integral part of the complete physical examination. An understanding of basic nail anatomy and familiarity with several basic types of nail line enable the clinician to diagnose and treat nail disorders and to recognize underlying systemic diseases, as each type of nail line has a particular differential diagnosis. Read More

    Reassessing Melanonychia Striata in Phototypes IV, V, and VI Patients.
    Dermatol Surg 2016 Feb;42(2):183-90
    Departments of *Dermatology and †Pathology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
    Background: Racial melanonychia striata is a nail plate dyschromia described as a gray coloration of the background in dermatoscopy and hypermelanosis in histology. However, many cases with brown or black coloration of the background in the dermatoscopic examination have been followed.

    Objective: Evaluate racial melanonychia striata dermatoscopical patterns and histological diagnosis in Fitzpatrick skin Types IV, V, or VI population. Read More

    Diagnostic criteria for and clinical review of melanonychia in Korean patients.
    J Am Acad Dermatol 2016 Jun 30;74(6):1121-7. Epub 2016 Jan 30.
    Department of Dermatology, School of Medicine, Pusan National University Hospital, Busan, Korea; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea. Electronic address:
    Background: Melanonychia may be the presenting sign of ungual melanoma. However, there are insufficient basic clinical data for melanonychia in Korean patients.

    Objective: We sought to identify basic clinical data and devise a classification algorithm for melanonychia. Read More

    Nail Deformities and Injuries.
    Prim Care 2015 Dec;42(4):677-91
    Department of Family and Community Medicine, Penn State Milton S. Hershey Medical Center, 500 University Avenue, Hershey, PA 17033, USA. Electronic address:
    A variety of nail deformities commonly presents in the primary care office. An understanding of nail anatomy coupled with inspection of the nails at routine office visits can reveal undetected disorders. Some problems are benign, and treatment should be attempted by the primary care provider, such as onychomycosis, paronychia, or ingrown toenails. Read More

    Skin Cancer.
    Prim Care 2015 Dec;42(4):645-59
    Albion Family Clinic & Walkin, Unit 309-1620, Albion Road, Etobicoke, ON M9V4B4, Canada. Electronic address:
    Skin cancer accounts for most malignancies across the globe. They are primarily divided into melanoma and nonmelanoma skin malignancies. Nonmelanoma skin cancer includes basal cell carcinoma and squamous cell carcinoma. Read More

    Clinical, dermoscopic, and pathologic features of onychopapilloma: A review of 47 cases.
    J Am Acad Dermatol 2016 Mar 27;74(3):521-6. Epub 2015 Oct 27.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida. Electronic address:
    Background: Onychopapilloma is a benign neoplasm of the nail bed and the distal matrix. Although not uncommon in our experience, only up to 32 cases of this tumor have been reported in the literature.

    Objective: We sought to review the clinical, dermoscopic, and pathologic features of onychopapilloma. Read More

    Macular pigmentation complicating irritant contact dermatitis and viral warts in Laugier-Hunziker syndrome.
    Clin Exp Dermatol 2016 Apr 28;41(3):294-6. Epub 2015 Oct 28.
    Department of Dermatology, Singleton Hospital, Swansea, UK.
    Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by macu-lar pigmentation of the lips and oral mucosa, with frequent longitudinal melanonychia. Involvement of other areas, such as the genitalia and fingers, has rarely been described. LHS is a benign condition with no known systemic manifestations. Read More

    Nail Disease for the Primary Care Provider.
    Med Clin North Am 2015 Nov 4;99(6):1213-26. Epub 2015 Sep 4.
    Division of Dermatology, University of Washington School of Medicine, 1959 Northeast Pacific Street, BB-1353, Box 356524, Seattle, WA 98195-6524, USA.
    Nail disorders are a common presenting complaint for both the primary care physician and the dermatologist. Nail diagnoses are broad in scope and include infectious, inflammatory, and neoplastic conditions. Onychomycosis is an especially common nail condition, and treatment should always be preceded by appropriate fungal studies for confirmation of diagnosis. Read More

    Scattered atypical melanocytes with hyperchromatic nuclei in the nail matrix: diagnostic clue for early subungual melanoma in situ.
    J Cutan Pathol 2016 Jan 5;43(1):41-52. Epub 2015 Nov 5.
    Division of Dermatology, Loyola University Medical Center, Maywood, IL, USA.
    Background: The lack of highly specific clinical and histopathological criteria has contributed to the delay in diagnosis of subungual melanoma in situ in its early stages.

    Methods: Eighteen cases of subungual melanoma in situ, the largest series reported to date, were analyzed to characterize the clinical and histopathological findings of early stages of subungual melanoma in situ along with five cases of nail matrix nevus and five cases of subungual lentigo serving as histologic control.

    Results: Clinically, longitudinal melanonychia was present in all 18 cases of subungual melanoma in situ, consisting of irregular dark brown to black streaks within a brown background with (11 cases) or without Hutchinson's sign. Read More

    Laugier-Hunziker syndrome--Case report.
    An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):223-5
    Clinical Center of Serbia, Belgrade, RS.
    Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features presented, dermoscopic findings and exclusion of underlying systemic diseases. Read More

    Melanonychia Secondary to Long-Term Treatment with Hydroxycarbamide: An Essential Thrombocytosis Case.
    Case Rep Hematol 2015 2;2015:653178. Epub 2015 Aug 2.
    Department of Hematology, School of Medicine, Hacettepe University, 0100 Ankara, Turkey.
    Hydroxycarbamide is used in the treatment of essential thrombocytosis and other myeloproliferative disorders. We report the case of a 63-year-old woman with essential thrombocytosis who had melanonychia after the long-term use of the hydroxycarbamide with a dose of 1000 mg/day. Two years after the initiation of the hydroxycarbamide, our patient had pain on her toes and melanonychia on her nails. Read More

    Pigmented lesions of the nail unit.
    Semin Cutan Med Surg 2015 Jun;34(2):101-8
    Departments of Dermatology and Pathology, University of California, San Francisco, California, USA.
    Longitudinal melanonychia originates from pigmented and/or melanocytic lesions of the nail unit. It may be a less-common entity encountered in dermatologic practice, but it is often a vexing one. Lesions occurring at this location present particular problems due to the unfamiliarity with clinical assessment, their relative inaccessibility, requiring more surgical finesse, and the lack of experience with histopathologic examination. Read More

    Subungual Congenital Nevus with Recurrent Nevus Phenomenon.
    Pediatr Dermatol 2015 Sep-Oct;32(5):e197-9. Epub 2015 Jul 7.
    Department of Dermatology, Royal Victoria Hospital, Belfast, UK.
    Melanonychia is uncommon. We report the first case of histopathologic recurrence of a completely excised subungual congenital nevus that presented as congenital melanonychia. Read More

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