1,601 results match your criteria Meigs Syndrome
Zhonghua Bing Li Xue Za Zhi 2018 Dec;47(12):967-969
Am J Obstet Gynecol 2018 Dec 7. Epub 2018 Dec 7.
Department of Respiratory Medicine, Kanazawa University Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa, Ishikawa, Japan.
Rev Sci Instrum 2018 Oct;89(10):10D113
EUROfusion Consortium, JET, Culham Science Centre, Abingdon OX14 3DB, United Kingdom.
Charge-exchange spectroscopy on JET has become particularly challenging with the introduction of the ITER-like wall. The line intensities are weaker and contaminated by many nuisance lines. We have therefore upgraded the instrumentation to improve throughput and allow the simultaneous measurement of impurity and fuel-ion charge exchange by splitting the light between two pairs of imaging spectrometers using dichroic beam splitters. Read More
Rev Sci Instrum 2018 Oct;89(10):10K107
Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6169, USA.
Since 2010, an in-vessel calibration light source (ICLS) has been used periodically on JET to calibrate a range of diagnostics at UV, visible, and IR wavelengths. During shutdowns, the ICLS (which is essentially an integrating sphere) is positioned within the vacuum vessel by the remote handling (RH) system. Following the 2013 calibration runs, several changes were made to improve the efficiency and quality of the calibrations. Read More
Am J Hum Genet 2018 Nov;103(5):691-706
Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:
C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is associated with multiple complex diseases. The genetic determinants of chronic inflammation remain largely unknown, and the causal role of CRP in several clinical outcomes is debated. We performed two genome-wide association studies (GWASs), on HapMap and 1000 Genomes imputed data, of circulating amounts of CRP by using data from 88 studies comprising 204,402 European individuals. Read More
Am J Forensic Med Pathol 2018 Oct 23. Epub 2018 Oct 23.
Department of Clinical Pathology, ASL 1 Imperiese - Sanremo Hospital, Sanremo, Italy.
Meigs syndrome is the triad of ascites, hydrothorax, and benign ovarian tumor (mostly fibroids). It is a diagnosis of exclusion, and the characteristic symptoms disappear after resection of the tumor. Instead, in Pseudo-Meigs syndrome, the triad includes a nonfibroma ovarian tumor. Read More
Cancer Epidemiol Biomarkers Prev 2018 Nov 18;27(11):1289-1297. Epub 2018 Oct 18.
Markey Cancer Center, University of Kentucky, Lexington, Kentucky.
Appalachia is a rural, socioeconomically disadvantaged region with high rates of cancer and obesity. Using community-based participatory research principles, the Appalachia Community Cancer Network tested an initiative to reduce weight among overweight and obese participants by partnering with churches, an important community-based institution in Appalachia. A group randomized trial was conducted with counties or groups of counties in five Appalachian states. Read More
Nat Genet 2018 Nov 8;50(11):1505-1513. Epub 2018 Oct 8.
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130 European-descent individuals (9% cases), after imputation to high-density reference panels. With these data, we (i) extend the inventory of T2D-risk variants (243 loci, 135 newly implicated in T2D predisposition, comprising 403 distinct association signals); (ii) enrich discovery of lower-frequency risk alleles (80 index variants with minor allele frequency <5%, 14 with estimated allelic odds ratio >2); (iii) substantially improve fine-mapping of causal variants (at 51 signals, one variant accounted for >80% posterior probability of association (PPA)); (iv) extend fine-mapping through integration of tissue-specific epigenomic information (islet regulatory annotations extend the number of variants with PPA >80% to 73); (v) highlight validated therapeutic targets (18 genes with associations attributable to coding variants); and (vi) demonstrate enhanced potential for clinical translation (genome-wide chip heritability explains 18% of T2D risk; individuals in the extremes of a T2D polygenic risk score differ more than ninefold in prevalence). Read More
Dis Mon 2018 Sep 28. Epub 2018 Sep 28.
Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville, FL, USA. Electronic address:
Obstetric and gynecologic pleural effusions may occur in the setting of different diseases and conditions, early and appropriate recognition of the different etiologies of these effusions will aid in appropriate treatment management. In this paper we will give an overview of the different pleural effusion etiologies that may be encountered including catamenial hemothorax, ovarian hyperstimulation syndrome, the different Meigs' syndromes and benign peripartum pleural effusion. Read More
J Diabetes Complications 2018 Sep 17. Epub 2018 Sep 17.
Department of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Aims: To determine the association between 20-year trajectories in insulin resistance (IR) since young adulthood and appendicular lean mass (ALM) at middle-age in adults without diabetes.
Methods: A prospective cohort study was designed among young and middle-aged US men (n = 925) and women (n = 1193). Fasting serum glucose and insulin were measured five times in 1985-2005. Read More
Hum Genet 2018 Oct 28;137(10):795-806. Epub 2018 Sep 28.
Division of Medical Genetics, School of Medicine, University of Washington Medical Center, Seattle, WA, USA.
Although ~ 25% of colorectal cancer or polyp (CRC/P) cases show familial aggregation, current germline genetic testing identifies a causal genotype in the 16 major genes associated with high penetrance CRC/P in only 20% of these cases. As there are likely other genes underlying heritable CRC/P, we evaluated the association of variation at novel loci with CRC/P. We evaluated 158 a priori selected candidate genes by comparing the number of rare potentially disruptive variants (PDVs) found in 84 CRC/P cases without an identified CRC/P risk-associated variant and 2440 controls. Read More
Am J Manag Care 2018 Sep;24(9):399-404
Division of General Internal Medicine and Diabetes Population Health Research Center, Massachusetts General Hospital/Harvard Medical School, 50 Staniford St, 9th Fl, Boston, MA 02114. Email:
Objectives: Reducing utilization of high-cost healthcare services is a common population health goal. Food insecurity-limited access to nutritious food owing to cost-is associated with chronic disease, but its relationship with healthcare utilization is understudied. We tested whether food insecurity is associated with increased emergency department (ED) visits, hospitalizations, and related costs. Read More
Ann Vasc Surg 2018 Sep 11. Epub 2018 Sep 11.
Department of Thoracic & Cardiovascular Surgery, Yeungnam University Medical Center, Daegu, Korea. Electronic address:
Background: Pseudo-Meigs syndrome is an unusual condition involving pelvic tumors, excluding ovarian fibroma, and is associated with ascites and hydrothorax. Pseudo-Meigs syndrome originating from uterine leiomyoma is an even rarer condition. Intravenous leiomyomatosis originating from uterine tumors, which extend from the inferior vena cava to the right heart chambers, is also extremely rare. Read More
Eur J Obstet Gynecol Reprod Biol 2018 Oct 5;229:207-208. Epub 2018 Sep 5.
University Department of Obstetrics and Gynecology and Pathology, Sveti Duh University Hospital, Croatian Catholic University, Zagreb, Croatia.
Medicine (Baltimore) 2018 Aug;97(34):e11926
Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Ovarian fibroma/fibrothecoma with elevated serum OC125 antigen (CA125) is rarely encountered in clinical practice, and also easily misdiagnosed as epithelial ovarian carcinoma (EOC). The aim of this study was to investigate the clinicopathological features of ovarian fibroma/fibrothecoma with elevated serum CA125.In total, 580 patients who underwent primary surgery and pathologically diagnosed as ovarian fibroma/fibrothecoma were retrospectively analyzed. Read More
ALTEX 2018 ;35(3):275-305
Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
For a long time, the discussion about animal testing vs its alternatives centered on animal welfare. This was a static warfare, or at least a gridlock, where life scientists had to take a position and make their value choices and hardly anyone changed sides. Technical advances have changed the frontline somewhat, with in vitro and in silico methods gaining more ground. Read More
J Radiol Case Rep 2018 Jan 31;12(1):17-26. Epub 2018 Jan 31.
Department of Obstetrics and Gynecology, Haaglanden Medical Center, The Hague, The Netherlands.
This case report presents three cases of Meigs' syndrome: a benign ovarian tumor with ascites and a hydrothorax. After removal of the ovarian tumor, the symptoms resolved and the patients became asymptomatic. In daily practice, Meigs' syndrome is at first sight often mistaken for ovarian cancer. Read More
J Rheumatol 2018 Jun;45(6):877-878
Institute for Autoimmune Systemic and Neurological Disorders, and Academy of Athens, Athens, Greece.
Diabetes Care 2018 Jun 26;41(6):e99-e100. Epub 2018 Apr 26.
Quest Diagnostics, San Juan Capistrano, CA
Diabetes 2018 06 18;67(6):1206. Epub 2018 Apr 18.
Rheumatology (Oxford) 2018 Apr 11. Epub 2018 Apr 11.
Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain.
Objectives: The objective of this study was to assess the effect that triple therapy (anticoagulation plus CS plus plasma exchange and/or IVIGs) has on the mortality risk of patients with catastrophic APS (CAPS) included in the CAPS Registry.
Methods: Patients from the CAPS Registry were grouped based on their treatments: triple therapy; drugs included in the triple therapy but in different combinations; and none of the treatments included in the triple therapy. The primary endpoint was all-cause mortality. Read More
Nat Genet 2018 Apr 9;50(4):559-571. Epub 2018 Apr 9.
Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10); of these, 16 map outside known risk-associated loci. We make two important observations. Read More
Diabetologia 2018 06 6;61(6):1315-1324. Epub 2018 Apr 6.
Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Aims/hypothesis: Identifying the metabolite profile of individuals with normal fasting glucose (NFG [<5.55 mmol/l]) who progressed to type 2 diabetes may give novel insights into early type 2 diabetes disease interception and detection.
Methods: We conducted a population-based prospective study among 1150 Framingham Heart Study Offspring cohort participants, age 40-65 years, with NFG. Read More
JAMA Cardiol 2018 Jun;3(6):463-472
College of Public Health, University of Kentucky, Lexington.
Importance: Tumor necrosis factor α (TNF-α) is a proinflammatory cytokine with manifold consequences for mammalian pathophysiology, including cardiovascular disease. A deeper understanding of TNF-α biology may enhance treatment precision.
Objective: To conduct an epigenome-wide analysis of blood-derived DNA methylation and TNF-α levels and to assess the clinical relevance of findings. Read More
Gynecol Oncol 2018 06 7;149(3):447-454. Epub 2018 Mar 7.
Brigham & Women's Hospital, Boston, MA, United States.
Joe V. Meigs was a visionary clinician and an early adopter of radical techniques in the surgical treatment of ovarian cancer. His 1934 textbook "Tumors of the Female Pelvic Organs", consolidated his approach to this "hopeless" disease, with pearls on diagnosis, outcomes, and even speculations about the benefits of minimally invasive surgery. Read More
Circulation 2018 May 14;137(21):2203-2214. Epub 2018 Feb 14.
Massachusetts General Hospital, Boston. Department of Mathematics and Statistics (J.P., R.B.D.).
Background: Cardiovascular disease (CVD) risk is elevated in HIV-infected individuals, with contributions from both traditional and nontraditional risk factors. The accuracy of established CVD risk prediction functions in HIV is uncertain. We sought to assess the performance of 3 established CVD risk prediction functions in a longitudinal cohort of HIV-infected men. Read More
J Ovarian Res 2018 Feb 2;11(1):11. Epub 2018 Feb 2.
Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan.
Background: Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Pseudo-Meigs' syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery.
Case Presentation: A 50-year-old woman with abdominal distention and dyspnoea was referred to our hospital. Read More
Ecol Appl 2018 Apr 26;28(3):798-815. Epub 2018 Mar 26.
Rubenstein School of Environment and Natural Resources, University of Vermont, Burlington, Vermont, 05405, USA.
Wind is one of the most important natural disturbances influencing forest structure, ecosystem function, and successional processes worldwide. This study quantifies the stand-scale effects of intermediate-severity windstorms (i.e. Read More
Hypertension 2018 03 15;71(3):422-428. Epub 2018 Jan 15.
From the Department of Clinical and Experimental Medicine, University of Pisa, Italy (V.T.); Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico (C.G.-V.); Division of General Internal Medicine Division, Massachusetts General Hospital, Boston (J.B.M.); Department of Medicine, Harvard Medical School, Boston, MA (J.B.M.); and CNR Institute of Clinical Physiology, Pisa, Italy (E.F.).
Type 2 diabetes mellitus and hypertension overlap in the population. In many subjects, development of diabetes mellitus is characterized by a relatively rapid increase in plasma glucose values. Whether a similar phenomenon occurs during the development of hypertension is not known. Read More
J Clin Endocrinol Metab 2018 04;103(4):1380-1392
NorthShore University HealthSystem, Evanston, Illinois.
Context: Vitamin D inadequacy is common in the adult population of the United States. Although the genetic determinants underlying vitamin D inadequacy have been studied in people of European ancestry, less is known about populations with Hispanic or African ancestry.
Objective: The Trans-Ethnic Evaluation of Vitamin D (TRANSCEN-D) genomewide association study (GWAS) consortium was assembled to replicate genetic associations with 25-hydroxyvitamin D [25(OH)D] concentrations from the Study of Underlying Genetic Determinants of Vitamin D and Highly Related Traits (SUNLIGHT) meta-analyses of European ancestry and to identify genetic variants related to vitamin D concentrations in African and Hispanic ancestries. Read More
Diabetes Care 2018 Mar 5;41(3):e25-e26. Epub 2018 Jan 5.
Division of Research, Kaiser Permanente, Oakland, CA.
Am J Cardiol 2018 Feb 23;121(4):485-490. Epub 2017 Nov 23.
Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:
We aimed to evaluate atherosclerotic cardiovascular disease (ASCVD) risk estimates and guideline-based statin use for primary prevention of ASCVD in adults with congenital heart disease (ACHD). This was a case-controlled, retrospective study of 248 cases and 744 age- and gender-matched controls at a tertiary care referral center. ASCVD risk scores were calculated and used to assess indication for statin treatment for primary prevention per the 2013 American College of Cardiology and American Heart Association guideline on assessment of cardiovascular risk. Read More
Sci Data 2017 12 19;4:170179. Epub 2017 Dec 19.
Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple ancestries. Over 27M SNPs, indels, and structural variants were identified, including 99% of low-frequency (minor allele frequency [MAF] 0.1-5%) non-coding variants in the whole-genome sequenced individuals and 99. Read More
Ultrasound Q 2018 Mar;34(1):23-28
Meig syndrome is the triad of benign ovarian tumor, ascites, and pleural effusion. Pseudo-Meig syndrome mimics the Meig syndrome triad; however, in pseudo-Meig syndrome, the ovarian tumor usually represents a primary malignancy or metastases. Differentiating Meig from pseudo-Meig syndrome is challenging both clinically and with diagnostic imaging but is important because prognoses for these distinct entities are drastically different. Read More
Environ Int 2018 02 20;111:14-22. Epub 2017 Dec 20.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States; Cardiovascular Epidemiology Research Unit, Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States. Electronic address:
Objective: To examine associations of proximity to major roadways, sustained exposure to fine particulate matter (PM), and acute exposure to ambient air pollutants with adipokines and measures of glucose homeostasis among participants living in the northeastern United States.
Methods: We included 5958 participants from the Framingham Offspring cohort examination cycle 7 (1998-2001) and 8 (2005-2008) and Third Generation cohort examination cycle 1 (2002-2005) and 2 (2008-2011), who did not have type 2 diabetes at the time of examination visit. We calculated 2003 annual average PM at participants' home address, residential distance to the nearest major roadway, and daily PM, black carbon (BC), sulfate, nitrogen oxides (NO), and ozone concentrations. Read More
Curr Diab Rep 2017 Nov 4;17(12):135. Epub 2017 Nov 4.
Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02141, USA.
Purpose Of Review: The purpose of this review was to summarize and reflect on advances over the past decade in human genetic and metabolomic discovery with particular focus on their contributions to type 2 diabetes (T2D) risk prediction.
Recent Findings: In the past 10 years, a combination of advances in genotyping efficiency, metabolomic profiling, bioinformatics approaches, and international collaboration have moved T2D genetics and metabolomics from a state of frustration to an abundance of new knowledge. Efforts to control and prevent T2D have failed to stop this global epidemic. Read More
Diabetologia 2018 02 2;61(2):317-330. Epub 2017 Nov 2.
Division Of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Aims/hypothesis: Sugar-sweetened beverages (SSBs) are a major dietary contributor to fructose intake. A molecular pathway involving the carbohydrate responsive element-binding protein (ChREBP) and the metabolic hormone fibroblast growth factor 21 (FGF21) may influence sugar metabolism and, thereby, contribute to fructose-induced metabolic disease. We hypothesise that common variants in 11 genes involved in fructose metabolism and the ChREBP-FGF21 pathway may interact with SSB intake to exacerbate positive associations between higher SSB intake and glycaemic traits. Read More
Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.
Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein cholesterol (LDL-C), and/or triglycerides (TG). At two loci (JAK2 and A1CF), experimental analysis in mice showed lipid changes consistent with the human data. We also found that: (i) beta-thalassemia trait carriers displayed lower TC and were protected from coronary artery disease (CAD); (ii) excluding the CETP locus, there was not a predictable relationship between plasma HDL-C and risk for age-related macular degeneration; (iii) only some mechanisms of lowering LDL-C appeared to increase risk for type 2 diabetes (T2D); and (iv) TG-lowering alleles involved in hepatic production of TG-rich lipoproteins (TM6SF2 and PNPLA3) tracked with higher liver fat, higher risk for T2D, and lower risk for CAD, whereas TG-lowering alleles involved in peripheral lipolysis (LPL and ANGPTL4) had no effect on liver fat but decreased risks for both T2D and CAD. Read More
Diabetes Care 2018 01 26;41(1):60-68. Epub 2017 Oct 26.
Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA
Objective: Hemoglobin A (HbA) can be used to assess type 2 diabetes (T2D) risk. We asked whether HbA was associated with T2D risk in four scenarios of clinical information availability: ) HbA alone, ) fasting laboratory tests, ) clinic data, and ) fasting laboratory tests and clinic data.
Research Design And Methods: We studied a prospective cohort of white ( = 11,244) and black ( = 2,294) middle-aged participants without diabetes in the Framingham Heart Study and Atherosclerosis Risk in Communities study. Read More
Atherosclerosis 2017 Nov 28;266:196-204. Epub 2017 Sep 28.
Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Background And Aims: Increased proinsulin relative to insulin levels have been associated with subclinical atherosclerosis (measured by carotid intima-media thickness (cIMT)) and are predictive of future cardiovascular disease (CVD), independently of established risk factors. The mechanisms linking proinsulin to atherosclerosis and CVD are unclear. A genome-wide meta-analysis has identified nine loci associated with circulating proinsulin levels. Read More
JAMA Intern Med 2017 Nov;177(11):1642-1649
Department of Medicine, Stanford University, Palo Alto, California.
Importance: Food insecurity is associated with high health care expenditures, but the effectiveness of food insecurity interventions on health care costs is unknown.
Objective: To determine whether the Supplemental Nutrition Assistance Program (SNAP), which addresses food insecurity, can reduce health care expenditures.
Design, Setting, And Participants: This is a retrospective cohort study of 4447 noninstitutionalized adults with income below 200% of the federal poverty threshold who participated in the 2011 National Health Interview Survey (NHIS) and the 2012-2013 Medical Expenditure Panel Survey (MEPS). Read More
AIDS 2018 Jan;32(1):59-67
Division of General Internal Medicine.
Objective: To determine if the greater risk of ischemic stroke observed in women living with HIV infection (WLWH) compared with HIV-uninfected women persists after accounting for both traditional and sex-specific stroke risk factors.
Methods: We performed an observational cohort study of WLWH (n = 1214) and demographics-matched HIV-uninfected women (n = 12 041) seen between 1996 and 2011 at two tertiary care hospitals in Boston. We used Cox proportional hazards regression analyses to model time to ischemic stroke, adjusting first for demographics and traditional stroke risk factors and then for sex-specific stroke risk factors, including menopause and estrogen use. Read More
Am J Psychoanal 2017 Sep;77(3):313-331
, 1629 NW 19th Circle, Gainesville, FL, 32065, USA.
After hearing Ferenczi's talks on theory and practice in New York in 1926, psychiatrist Harry Stack Sullivan urged his friend and colleague Clara Thompson to get analyzed by Ferenczi so they could learn his technique. After saving for 2 years Thompson was a patient of Ferenczi for three summers and then moved to Budapest full-time for analysis until Ferenczi's death. Two years after she returned to New York she attempted to analyze Sullivan. Read More
PLoS Med 2017 Sep 12;14(9):e1002383. Epub 2017 Sep 12.
Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.
Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or glycemic (associated with other glucose-related traits). Read More
BMJ Case Rep 2017 Aug 11;2017. Epub 2017 Aug 11.
Department of Obstetrics and Gynaecology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
A 44-year-old woman presented with 3 months' history of painless progressive abdominal distension and weight loss of more than 15 kg. Clinically a pelviabdominal mass with ascites was detected. CT scan of the pelvis and abdomen showed a subserosal leiomyoma with huge amount of ascites. Read More
J Nutr 2017 09 2;147(9):1764-1775. Epub 2017 Aug 2.
Nutritional Epidemiology, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, and Tufts University Friedman School of Nutrition Science and Policy, Boston, MA;
Inconsistent evidence describes the association between dietary intake of dairy and milk-based products and type 2 diabetes (T2D) risk. Our objective was to assess associations between consumption of milk-based products, incident prediabetes, and progression to T2D in the Framingham Heart Study Offspring Cohort. Total dairy and milk-based product consumption was assessed by ≤4 food-frequency questionnaires across a mean of 12 y of follow-up in 2809 participants [mean ± SD age: 54. Read More
Sultan Qaboos Univ Med J 2017 May 20;17(2):e229-e233. Epub 2017 Jun 20.
Department of Obstetrics & Gynecology, Lok Nayak Jai Prakash Narayan Hospital, New Delhi, Delhi, India.
The monodermal teratoma is a rare ovarian tumour; however, presenting with pseudo-Meigs' syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Read More
Health Serv Res 2018 Jun 13;53(3):1600-1620. Epub 2017 Jun 13.
Division of General Internal Medicine, University of California San Francisco, San Francisco, CA.
Objective: To determine whether food insecurity, limited or uncertain food access owing to cost, is associated with greater health care expenditures.
Data Source/study Setting: Nationally representative sample of the civilian noninstitutionalized population of the United States (2011 National Health Interview Survey [NHIS] linked to 2012-2013 Medication Expenditure Panel Survey [MEPS]).
Study Design: Longitudinal retrospective cohort. Read More
PLoS One 2017 7;12(6):e0179172. Epub 2017 Jun 7.
Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Background: Food insecurity, the uncertain ability to access adequate food, can limit adherence to dietary measures needed to prevent and manage cardiometabolic conditions. However, little is known about temporal trends in food insecurity among those with diet-sensitive cardiometabolic conditions.
Methods: We used data from the Continuous National Health and Nutrition Examination Survey (NHANES) 2005-2012, analyzed in 2015-2016, to calculate trends in age-standardized rates of food insecurity for those with and without the following diet-sensitive cardiometabolic conditions: diabetes mellitus, hypertension, coronary heart disease, congestive heart failure, and obesity. Read More