21,892 results match your criteria Medicine [Journal]


Thymic size is increased by infancy, but not pregnancy, nutritional supplementation in rural Gambian children: a randomized clinical trial.

BMC Med 2019 Feb 18;17(1):38. Epub 2019 Feb 18.

MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine, Atlantic Boulevard, Fajara, PO Box 273, Banjul, The Gambia.

Background: Thymic size in early infancy predicts subsequent survival in low-income settings. The human thymus develops from early gestation, is most active in early life and is highly sensitive to malnutrition. Our objective was to test whether thymic size in infancy could be increased by maternal and/or infant nutritional supplementation. Read More

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http://dx.doi.org/10.1186/s12916-019-1264-2DOI Listing
February 2019

Correction to: A randomised controlled trial of a mitochondrial therapeutic target for bipolar depression: mitochondrial agents, N-acetylcysteine, and placebo.

BMC Med 2019 Feb 17;17(1):35. Epub 2019 Feb 17.

IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Deakin University, P.O. Box 291, Geelong, VIC, Australia.

The original article [1] contained two minor errors. Read More

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http://dx.doi.org/10.1186/s12916-019-1280-2DOI Listing
February 2019

A systematic review of multi-level stigma interventions: state of the science and future directions.

BMC Med 2019 Feb 15;17(1):41. Epub 2019 Feb 15.

Department of Health Behavior, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC, USA.

Background: Researchers have long recognized that stigma is a global, multi-level phenomenon requiring intervention approaches that target multiple levels including individual, interpersonal, community, and structural levels. While existing interventions have produced modest reductions in stigma, their full reach and impact remain limited by a nearly exclusive focus targeting only one level of analysis.

Methods: We conducted the first systematic review of original research on multi-level stigma-reduction interventions. Read More

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http://dx.doi.org/10.1186/s12916-018-1244-yDOI Listing
February 2019

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.

PLoS Med 2019 Feb 15;16(2):e1002745. Epub 2019 Feb 15.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Background: The emergence and spread of multidrug-resistant Plasmodium falciparum in the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass drug administration (MDA), the presumptive antimalarial treatment of an entire population to clear the subclinical parasite reservoir, is a strategy to accelerate malaria elimination. We report a cluster randomised trial to assess the effectiveness of dihydroartemisinin-piperaquine (DP) MDA in reducing falciparum malaria incidence and prevalence in 16 remote village populations in Myanmar, Vietnam, Cambodia, and the Lao People's Democratic Republic, where artemisinin resistance is prevalent. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002745DOI Listing
February 2019

Advancing health equity through cross-cutting approaches to health-related stigma.

BMC Med 2019 Feb 15;17(1):40. Epub 2019 Feb 15.

Uganda Youth Coalition on Adolescent Sexual Reproductive Health Rights and HIV, Kampala, Uganda.

Health-related stigma remains a major barrier to improving health and well-being for vulnerable populations around the world. This collection on stigma research and global health emerged largely as a result of a 2017 meeting on the "The Science of Stigma Reduction" sponsored by the US National Institutes of Health (NIH). An overwhelming consensus at the meeting was reached. Read More

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http://dx.doi.org/10.1186/s12916-019-1282-0DOI Listing
February 2019

The Health Stigma and Discrimination Framework: a global, crosscutting framework to inform research, intervention development, and policy on health-related stigmas.

BMC Med 2019 Feb 15;17(1):31. Epub 2019 Feb 15.

Yale University, New Haven, CT, USA.

Stigma is a well-documented barrier to health seeking behavior, engagement in care and adherence to treatment across a range of health conditions globally. In order to halt the stigmatization process and mitigate the harmful consequences of health-related stigma (i.e. Read More

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http://dx.doi.org/10.1186/s12916-019-1271-3DOI Listing
February 2019

Implementation science and stigma reduction interventions in low- and middle-income countries: a systematic review.

BMC Med 2019 Feb 15;17(1). Epub 2019 Feb 15.

Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.

Background: Interventions to alleviate stigma are demonstrating effectiveness across a range of conditions, though few move beyond the pilot phase, especially in low- and middle-income countries (LMICs). Implementation science offers tools to study complex interventions, understand barriers to implementation, and generate evidence of affordability, scalability, and sustainability. Such evidence could be used to convince policy-makers and donors to invest in implementation. Read More

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http://dx.doi.org/10.1186/s12916-018-1237-xDOI Listing
February 2019

A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries.

BMC Med 2019 Feb 15;17(1):17. Epub 2019 Feb 15.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.

Background: Stigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. However, the literature discussing the relationship between stigma and health outcomes is largely fragmented within disease-specific siloes, thus limiting the identification of common moderators or mechanisms through which stigma potentiates adverse health outcomes as well as the development of broadly relevant stigma mitigation interventions.

Methods: We conducted a scoping review to provide a critical overview of the breadth of research on stigma for each of the five aforementioned conditions in LMICs, including their methodological strengths and limitations. Read More

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http://dx.doi.org/10.1186/s12916-019-1250-8DOI Listing
February 2019

Out of the silos: identifying cross-cutting features of health-related stigma to advance measurement and intervention.

BMC Med 2019 Feb 15;17(1):13. Epub 2019 Feb 15.

College of Global Public Health, New York University, New York, NY, USA.

Background: Many health conditions perceived to be contagious, dangerous or incurable, or resulting in clearly visible signs, share a common attribute - an association with stigma and discrimination. While the etiology of stigma may differ between conditions and, sometimes, cultural settings, the manifestations and psychosocial consequences of stigma and discrimination are remarkably similar. However, the vast majority of studies measuring stigma or addressing stigma through interventions employ a disease-specific approach. Read More

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https://bmcmedicine.biomedcentral.com/articles/10.1186/s1291
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http://dx.doi.org/10.1186/s12916-018-1245-xDOI Listing
February 2019
2 Reads

Challenges and opportunities in examining and addressing intersectional stigma and health.

BMC Med 2019 Feb 15;17(1). Epub 2019 Feb 15.

Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: 'Intersectional stigma' is a concept that has emerged to characterize the convergence of multiple stigmatized identities within a person or group, and to address their joint effects on health and wellbeing. While enquiry into the intersections of race, class, and gender serves as the historical and theoretical basis for intersectional stigma, there is little consensus on how best to characterize and analyze intersectional stigma, or on how to design interventions to address this complex phenomenon. The purpose of this paper is to highlight existing intersectional stigma literature, identify gaps in our methods for studying and addressing intersectional stigma, provide examples illustrating promising analytical approaches, and elucidate priorities for future health research. Read More

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http://dx.doi.org/10.1186/s12916-018-1246-9DOI Listing
February 2019

Participatory praxis as an imperative for health-related stigma research.

BMC Med 2019 Feb 15;17(1):32. Epub 2019 Feb 15.

Uganda Youth Coalition on Adolescent SRHR and HIV, Busia, Uganda.

Background: Participatory praxis is increasingly valued for the reliability, validity, and relevance of research results that it fosters. Participatory methods become an imperative in health-related stigma research, where the constitutive elements of stigma, healthcare settings, and research each operate on hierarchies that push those with less social power to the margins.

Discussion: Particularly for people who are stigmatized, participatory methods balance the scales of equity by restructuring power relationships. Read More

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http://dx.doi.org/10.1186/s12916-019-1263-3DOI Listing
February 2019

Stigma in health facilities: why it matters and how we can change it.

BMC Med 2019 Feb 15;17(1):25. Epub 2019 Feb 15.

Centre for Longitudinal & Life Course Studies, University of Antwerp, Sint-Jacobstraat 2, B-2000, Antwerp, Belgium.

Stigma in health facilities undermines diagnosis, treatment, and successful health outcomes. Addressing stigma is fundamental to delivering quality healthcare and achieving optimal health. This correspondence article seeks to assess how developments over the past 5 years have contributed to the state of programmatic knowledge-both approaches and methods-regarding interventions to reduce stigma in health facilities, and explores the potential to concurrently address multiple health condition stigmas. Read More

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http://dx.doi.org/10.1186/s12916-019-1256-2DOI Listing
February 2019

Community-, facility-, and individual-level outcomes of a district mental healthcare plan in a low-resource setting in Nepal: A population-based evaluation.

PLoS Med 2019 Feb 14;16(2):e1002748. Epub 2019 Feb 14.

Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Background: In low-income countries, care for people with mental, neurological, and substance use (MNS) disorders is largely absent, especially in rural settings. To increase treatment coverage, integration of mental health services into community and primary healthcare settings is recommended. While this strategy is being rolled out globally, rigorous evaluation of outcomes at each stage of the service delivery pathway from detection to treatment initiation to individual outcomes of care has been missing. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002748DOI Listing
February 2019

Solitary rectal ulcer syndrome: A systematic review: Erratum.

Authors:

Medicine (Baltimore) 2019 Feb;98(7):e14662

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http://dx.doi.org/10.1097/MD.0000000000014662DOI Listing
February 2019

Electrical stimulation on adverse events caused by chemotherapy in patients with cervical cancer: A protocol for a systematic review of randomized controlled trial.

Medicine (Baltimore) 2019 Feb;98(7):e14609

Department of Gynecology.

Background: This protocol of systematic review aims to investigate the effectiveness of electrical stimulation (ES) on adverse events (AEs) caused by chemotherapy in patients with cervical cancer (CC).

Methods: This systematic review of randomized controlled trials will be identified through searchers of PUBMED, PsycINFO, Scopus, Opengrey, Cochrane Central Register of Controlled Trials, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database. All the sources will be searched from the inception to the date of study search ran. Read More

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http://dx.doi.org/10.1097/MD.0000000000014609DOI Listing
February 2019

Diagnostic value of using epicardial fat measurement on screening low-dose chest CT for the prediction of metabolic syndrome: A cross-validation study.

Medicine (Baltimore) 2019 Feb;98(7):e14601

Department of Radiology, Ilsan Paik Hospital, Goyang, Republic of Korea.

There has been a marked increase in the use of low-dose computed tomography (LDCT) for lung cancer screening. However, the potential of LDCT to predict metabolic syndrome (MetS) has not been well-documented in this risk-sharing population. We assessed the reliability of epicardial fat volume (EFV) and epicardial fat area (EFA) measurements on chest LDCT for prediction of MetS. Read More

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http://dx.doi.org/10.1097/MD.0000000000014601DOI Listing
February 2019

Fetal cardiac examination can affect patients' preference on invasive tests: A new data on maternal anxiety indicated karyotyping.

Medicine (Baltimore) 2019 Feb;98(7):e14599

Izmir Katip Celebi University, School of Medicine, Obstetrics and Gynecology Department, Maternal - Fetal Medicine Unit.

Background: Prenatal screening for aneuploidies has seen great changes over the last 2 decades. But there is still no non-invasive diagnostic test. Therefore, prenatal invasive procedures are still being routinely performed due to maternal anxiety. Read More

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http://dx.doi.org/10.1097/MD.0000000000014599DOI Listing
February 2019

The telomere length of peripheral blood cells is associated with the risk of ischemic stroke in Han population of northern China.

Medicine (Baltimore) 2019 Feb;98(7):e14593

Medical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang, China.

Background: Telomere length is closely related to the onset and prognosis of ischemic stroke. This study was to investigate the relationship between telomere length and the incidence of ischemic stroke in Han population of northern China.

Methods: In the present study, 152 patients with ischemic stroke were selected as the case group, and 152 healthy persons were used as the control group. Read More

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http://dx.doi.org/10.1097/MD.0000000000014593DOI Listing
February 2019

IL-1 inhibition improves insulin resistance and adipokines in rheumatoid arthritis patients with comorbid type 2 diabetes: An observational study.

Medicine (Baltimore) 2019 Feb;98(7):e14587

Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila.

Recently, it has been shown that some well-known pathogenic mediators in rheumatoid arthritis (RA), such as interleukin-1β (IL-1β) and tumor necrosis factor (TNF), could play a pathogenic role in insulin resistance and (IR) and type 2 diabetes (T2D).In this 6-month longitudinal study, we aimed at investigating if the inhibition of IL-1 or TNF is associated with an improvement of IR in RA patients with comorbid T2D and the possible effects on selected serum adipokines. RA patients with comorbid T2D were recruited among those undergoing treatment with anakinra (ANA) or with TNF inhibitor (TNFi). Read More

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http://dx.doi.org/10.1097/MD.0000000000014587DOI Listing
February 2019

Effects of traditional Chinese exercise on cognitive and psychological outcomes in older adults with mild cognitive impairment: A systematic review and meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14581

The Department of Nursing, Tianjin Huanhu Hospital, Tianjin, China.

Background: Mild cognitive impairment (MCI) can be a stage of pre-dementia. Although the traditional Chinese exercise (TCE) has benefits associated with cognitive functions, the effects of the TCE on cognitive functions of older patients with MCI remain controversial. This study performs a meta-analysis to quantify the efficiency of TCE for older individuals on cognitive and psychological outcomes. Read More

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http://dx.doi.org/10.1097/MD.0000000000014581DOI Listing
February 2019

Assessment of the diagnostic value of using serum CA125 and GI-RADS system in the evaluation of adnexal masses.

Medicine (Baltimore) 2019 Feb;98(7):e14577

Department of Gynecology and Obstetrics, Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University, Chengdu.

Cancer antigen 125 (CA125) is a valuable tumor marker for ovarian cancer. Gynecology Imaging Reporting and Data System (GI-RADS) is proved to be effective at identifying the adnexal masses. We investigated whether the combination of these two methods can improve the diagnostic accuracy of ovarian cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000014577DOI Listing
February 2019
5.723 Impact Factor

Acupuncture for perimenopausal depressive disorder: A systematic review and meta-analysis protocol.

Medicine (Baltimore) 2019 Feb;98(7):e14574

Yunnan University of Chinese Medicine, Kunming, Yunnan.

Background: Perimenopausal depressive disorder (PDD) is a disease that plagues many perimenopausal women. There is an urgent need for a safe way to treat the disease. With few side effects, acupuncture treatment for PDD has been gradually accepted. Read More

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http://dx.doi.org/10.1097/MD.0000000000014574DOI Listing
February 2019

Surveillance of non-muscle invasive bladder cancer using fluorescence in situ hybridization: Protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14573

Department of Urology, Institute of Urology.

Background: To evaluate the diagnostic effectiveness and predictive value of fluorescence in situ hybridization (FISH) in the surveillance of non-muscle invasive bladder cancer (NMIBC).

Methods: PubMed/Medline, EMBASE, Web of Science, Ovid, Web of Knowledge, and Cochrane Library will be searched for studies related to the topic. The identification, inclusion, and exclusion flowcharts will be conducted according to preferred reporting items for systematic reviews and meta-analysis guidelines. Read More

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http://dx.doi.org/10.1097/MD.0000000000014573DOI Listing
February 2019

Randomized, open-label, multicenter study of azithromycin compared with doxycycline for treating anorectal Chlamydia trachomatis infection concomitant to a vaginal infection (CHLAZIDOXY study).

Medicine (Baltimore) 2019 Feb;98(7):e14572

University Bordeaux.

Background: Chlamydia trachomatis can lead to a persistent infection in the lower gastrointestinal tract, suggesting a potential role of autoinoculation of cervical chlamydial infection from the rectal site, contributing to repeat infections. Moreover, around 75% of women with urogenital C. trachomatis have concurrent anorectal infection. Read More

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http://Insights.ovid.com/crossref?an=00005792-201902150-0008
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http://dx.doi.org/10.1097/MD.0000000000014572DOI Listing
February 2019
2 Reads

The effectiveness and safety of cervus and cucumis polypeptide injection in promoting fracture healing after bone fracture surgeries: Protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14571

Department of Orthopaedics, Inner Mongolia Baogang Hospital, The Third Affiliated Hospital of Inner Mongolia Medical University, Baotou, Inner Mongolia Autonomous Region, China.

Background: Bone fractures are a common occurrence, and, according to clinical investigations, approximately 5% to 10% of patients with fractures will suffer from delayed healing or even non-healing. The high efficacy of traditional Chinese medicine in promoting fracture healing has been fully verified over a long history of diagnosis and treatment. Traditional Chinese medicine has a long history of applying Chinese herbs to treat fractures. Read More

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http://dx.doi.org/10.1097/MD.0000000000014571DOI Listing
February 2019

A novel inflammation-based prognostic index for patients with esophageal squamous cell carcinoma: Neutrophil lymphocyte ratio/prealbumin ratio.

Medicine (Baltimore) 2019 Feb;98(7):e14562

Department of Radiation Oncology, Shandong Provincial Qianfoshan Hospital affiliated to Shandong University, Jinan, Shandong, PR China.

NLR/Alb (neutrophil lymphocyte ratio/albumin ratio), is a prognostic index for esophageal cancer has been confirmed. Prealbumin (PA) is more sensitive to malnutrition than albumin. A new prognostic index, named neutrophil lymphocyte ratio/prealbumin ratio (NLR/PA), for predicting the survival time in patients with esophageal squamous cell carcinoma (ESCC) was proposed. Read More

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http://dx.doi.org/10.1097/MD.0000000000014562DOI Listing
February 2019

Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report.

Medicine (Baltimore) 2019 Feb;98(7):e14559

Department of Pediatrics.

Rationale: Pneumocystis jirovecii causes severe pneumonia in immunocompromised hosts. Human immunodeficiency virus infection, malignancy, solid organ or hematopoietic cell transplantation, and primary immune deficiency compose the risk factors for Pneumocystis pneumonia (PCP) in children, and PCP can be an initial clinical manifestation of primary immune deficiency.

Patient Concerns: A 5-month-old infant presented with cyanosis and tachypnea. Read More

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http://dx.doi.org/10.1097/MD.0000000000014559DOI Listing
February 2019
5 Reads

Dual anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody-positive crescent glomerulonephritis in a patient with monoclonal gammopathy of undetermined significance: A case report.

Medicine (Baltimore) 2019 Feb;98(7):e14557

Department of Nephrology.

Rationale: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and anti-glomerular basement membrane (GBM) antibody disease are both rare autoimmune diseases. Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common causes of plasma cell dyscrasias (PCD). The three entities can cause renal lesions via different mechanisms and, however, they have not been reported in a single patient with renal lesion. Read More

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http://dx.doi.org/10.1097/MD.0000000000014557DOI Listing
February 2019
1 Read

A novel computer navigation method for accurate percutaneous sacroiliac screw implantation: A technical note and literature review.

Medicine (Baltimore) 2019 Feb;98(7):e14548

Department of Orthopedics.

The purpose of this study was to assess the accuracy of percutaneous sacroiliac screw (PSS) placement assisted by screw view model of navigation system for treatment of sacroiliac fractures.Data pertaining to 18 consecutive patients with posterior pelvic ring fracture who received sacroiliac screw fixation between January 2015 and July 2018 at the Second Hospital of Jilin University were retrospectively analyzed. Kirschner wires were placed under the guidance of navigation's screw view mode. Read More

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http://Insights.ovid.com/crossref?an=00005792-201902150-0007
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http://dx.doi.org/10.1097/MD.0000000000014548DOI Listing
February 2019
1 Read

Incidence of surgical-site infection following open reduction and internal fixation of a distal femur fracture: An observational case-control study.

Medicine (Baltimore) 2019 Feb;98(7):e14547

Department of Orthopaedic Surgery.

Surgical-site infection (SSI) is a common complication in orthopedic surgery; however, SSI after surgically managed distal femur fractures was not well studied. The aim of this study was to investigate the incidence of SSI and identify some modifiable and nonmodifiable risk factors.The patients' electronic medical records (EMRs) were reviewed to identify those who sustained a distal femur fracture and treated by open reduction and internal fixation (ORIF) between March 2014 and February 2018. Read More

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http://dx.doi.org/10.1097/MD.0000000000014547DOI Listing
February 2019

Sarcopenia for predicting mortality among elderly nursing home residents: SARC-F versus SARC-CalF.

Medicine (Baltimore) 2019 Feb;98(7):e14546

Health Management Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, Sichuan, China.

Little is known about the prognostic value of the strength, assistance walking, rise from a chair, climb stairs, and falls questionnaire (SARC-F) and SARC-F combined with calf circumference (SARC-CalF) among elderly nursing home residents.To compare the prognostic value of SARC-F and SARC-CalF for mortality in this population.We conducted a prospective study in four nursing homes in western China. Read More

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http://dx.doi.org/10.1097/MD.0000000000014546DOI Listing
February 2019

Amiodarone and acupuncture for cardiac arrhythmia: Study protocol for a systematic review.

Medicine (Baltimore) 2019 Feb;98(7):e14544

First Ward of Cardiology Department, First Affiliated Hospital of Jiamusi University, Jiamusi, China.

Background: Amiodarone and acupuncture (AA) are commonly used to treat cardiac arrhythmia (CA). The objective of this systematic review is to assess the efficacy and safety of AA for patients with CA.

Methods: Randomized controlled trials (RCTs) of AA for CC will be searched from 9 databases including PubMed, EMBASE, Cochrane Library, Web of Science, Scopus, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP Information, and Wanfang Data from inception to February 1, 2019 without any limitations. Read More

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http://dx.doi.org/10.1097/MD.0000000000014544DOI Listing
February 2019

Pharmacologic interventions for postoperative nausea and vomiting after thyroidectomy: A protocol for systematic review and network meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14542

Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.

Background: We aimed to perform a network meta-analysis (NMA) to quantify and rank the efficacy and safety of the pharmacologic interventions for prophylactic use for postoperative nausea and vomiting (PONV) in patients undergoing thyroidectomies.

Methods: A systematic and comprehensive search will be performed using MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar, beginning from their inceptions to February 2019. Only randomized clinical trials on the efficacy and safety of pharmacologic interventions for prophylactic use in patients undergoing thyroidectomies will be included. Read More

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http://dx.doi.org/10.1097/MD.0000000000014542DOI Listing
February 2019

Bloodletting therapy for treating patients with chronic urticaria: A systematic review and meta-analysis protocol.

Medicine (Baltimore) 2019 Feb;98(7):e14541

Beijing University of Chinese Medicine, Beijing, China.

Background: Chronic urticaria is a common disease affecting patients' quality of life, and leading to substantial burden to both patients and society. Many trials have shown that bloodletting therapy is effective in treating chronic urticaria. There are currently no systematic reviews of bloodletting therapy for chronic urticaria. Read More

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http://dx.doi.org/10.1097/MD.0000000000014541DOI Listing
February 2019

Efficacy of tolvaptan for chronic heart failure: Study protocol for a systematic review of randomized controlled trial.

Medicine (Baltimore) 2019 Feb;98(7):e14540

First Ward of Cardiology Department, First Affiliated Hospital of Jiamusi University, Jiamusi, China.

Background: The protocol of this study will be proposed for systematic evaluation of the efficacy and safety of tolvaptan in the treatment of chronic heart failure (CHF).

Methods: We will retrieve the following electronic databases for randomized controlled trials assessing the efficacy of tolvaptan in patients with CHF: PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP Information, and Wanfang Data. Each database will be retrieved from inception to February 1, 2019 without any limitations. Read More

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http://dx.doi.org/10.1097/MD.0000000000014540DOI Listing
February 2019

Patient-controlled intravenous analgesia with tramadol and lornoxicam after thoracotomy: A comparison with patient-controlled epidural analgesia.

Medicine (Baltimore) 2019 Feb;98(7):e14538

To determine efficacy and safety of patient-controlled intravenous analgesia (PCIA) with tramadol and lornoxicam for postoperative analgesia, and its effects on surgical outcomes in patients following thoracotomy.The records of patients who underwent thoracotomy for lung resection between January 2014 and December 2014 at our institution were reviewed. The patients were divided into 2 groups according to postoperative pain treatment modalities. Read More

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http://dx.doi.org/10.1097/MD.0000000000014538DOI Listing
February 2019

Local recurrence of sinonasal renal cell-like adenocarcinoma: A CARE compliant case report.

Medicine (Baltimore) 2019 Feb;98(7):e14533

Department of Pathology.

Rationale: Sinonasal renal cell-like adenocarcinoma (SNRCLA) is a very rare sino-nasal carcinoma. Because SNRCLA has the same morphological features as other clear cell carcinomas, and some of them also occurred in sinonasal part, it is necessary to differentiate SNRCLA from these tumors.

Patient Concerns: A 42-year-old man presented with complaints of epistaxis for 1 day. Read More

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http://dx.doi.org/10.1097/MD.0000000000014533DOI Listing
February 2019

Nephrocalcinosis in adolescent girl with medullary sponge kidney and mild hemihypertrophy: A case report.

Medicine (Baltimore) 2019 Feb;98(7):e14529

Department of Pediatric Nephrology.

Rationale: Medullary sponge kidney (MSK) is a rare congenital abnormality characterized by cystic dilatation of the medullary collecting tubules. The disorder is likely to be complicated by nephrocalcinosis, urolithiasis, tubular dysfunctions, and urinary tract infections. In addition, it may be rarely associated with extrarenal anomalies. Read More

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http://dx.doi.org/10.1097/MD.0000000000014529DOI Listing
February 2019
1 Read

Spontaneous regression of cervical discs: Retrospective analysis of 14 cases.

Medicine (Baltimore) 2019 Feb;98(7):e14521

Department of Neurosurgery, Sakarya Training and Research Hospital, Sakarya, Turkey.

Cervical disc herniation is a condition which arises from compression of cervical spinal nerve root by the degenerated disc and vast majority of the patients are aged between 30 and 40 years. Spontaneous regression of cervical disc was first reported by Kriegerand Maniker in 1992. Our study is the second large series in literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000014521DOI Listing
February 2019

Allogeneic blood transfusion in 163 children with acute lymphocytic leukemia (a STROBE-compliant article).

Medicine (Baltimore) 2019 Feb;98(7):e14518

Department of Pediatrics, the First Affiliated Hospital of Zhengzhou University.

Little research has been done about the effects of allogeneic blood transfusion (ABT) on the recurrence and prognosis in the cases with childhood acute lymphocytic leukemia (cALL). In order to provide a basis for clinical safe blood transfusion, the data of 163 cases with cALL were retrospectively analyzed to explore the issue.The data of 163 cases with cALL between 2006 and 2011 were retrospectively analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000014518DOI Listing
February 2019

Effect of extracorporeal shock wave for tennis elbow: A protocol for systematic review of randomized controlled trial.

Medicine (Baltimore) 2019 Feb;98(7):e14517

Department of Orthopedics, Huludao Central Hospital, Huludao, China.

Background: Previous clinical studies have reported that extracorporeal shock wave (EPSW) is an effective treatment for patients with tennis elbow (TE). However, no systematic review has assessed its effectiveness and safety for the treatment of TE.

Methods: In this systematic review, we will search the potential eligible literature from the following electronic databases: Central, Embase, MEDLINE, CINAHL, and CNKI from inception to the present. Read More

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http://dx.doi.org/10.1097/MD.0000000000014517DOI Listing
February 2019

Biochip detection of BP180 autoantibodies in blister fluid for the serodiagnosis of bullous pemphigoid: A pilot study.

Medicine (Baltimore) 2019 Feb;98(7):e14514

Dermatology Unit, Department of Medicine, University of Padua, Via Vincenzo Gallucci 4, Padua, Italy.

Bullous pemphigoid is an autoimmune subepidermal blistering skin disease immunologically defined by autoantibodies directed against basement membrane zone antigens, the main of which is BP180. Laboratory tests are essential for diagnosis and include direct immunofluorescence and serologic assessments with indirect immunofluorescence and ELISA. Serology may be performed on blister fluid, in alternative to blood serum. Read More

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http://dx.doi.org/10.1097/MD.0000000000014514DOI Listing
February 2019

Alterations in fecal short-chain fatty acids in patients with irritable bowel syndrome: A systematic review and meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14513

Department of Gastroenterology, Peking University Third Hospital, No. 49 North Garden Rd., Haidian District, Beijing, 100191, China.

Background: Recent studies indicate that gut microbiota disorders potentially contribute to the pathogenesis of irritable bowel syndrome (IBS), which can be partly reflected by fecal short-chain fatty acids (SCFAs) generated from gut microbiota. Previous studies on SCFA alterations in patients with IBS have yielded conflicting results. No prior systematic review has been conducted on the alterations in fecal SCFAs in IBS patients. Read More

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http://dx.doi.org/10.1097/MD.0000000000014513DOI Listing
February 2019

Predictive factors of chemotherapy use in stage II nasopharyngeal carcinoma: A retrospective cohort study.

Medicine (Baltimore) 2019 Feb;98(7):e14512

Department of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China.

Identification of predictive factors of chemotherapy use and assessment of the roles of these factors in prognosis will aid therapeutic decision-making in stage II nasopharyngeal carcinoma (NPC).Using logistic regression, we retrospectively assessed factors predicting chemotherapy use in 251 stage II (2010  UICC/AJCC staging system) NPC patients. Five-year overall survival (OS), locoregional-free survival (LRFS), and distant metastasis-free survival (DMFS) were analyzed based on the predictive factors. Read More

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http://dx.doi.org/10.1097/MD.0000000000014512DOI Listing
February 2019
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Effectiveness of extracorporeal shock wave for low back pain: A protocol of systematic review.

Medicine (Baltimore) 2019 Feb;98(7):e14511

Second Ward of Orthopedis Department.

Background: Previous clinical trials have reported that extracorporeal shock wave (EPSW) can be used to treat low back pain (LBP), and have achieved satisfied effect. However, its effectiveness is still inconclusive. Thus, this systematic review will aim to assess the effectiveness and safety of EPSW for patients with LBP. Read More

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http://dx.doi.org/10.1097/MD.0000000000014511DOI Listing
February 2019

Efficacy of Duohuojisheng decoction monotherapy for the treatment of knee osteoarthritis: A protocol of a systematic review of randomized controlled trials.

Medicine (Baltimore) 2019 Feb;98(7):e14510

First Ward of Orthopedics Department, Inner Mongolia Xilin Gol League Hospital, Xilinhot, China.

Background: This systematic review investigates the efficacy and safety of Duohuojisheng decoction (DHJSD) monotherapy for the treatment of patients with knee osteoarthritis (KOA).

Methods: We searched relevant studies on DHJSD monotherapy for KOA from the databases of CENTRAL, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP Information, and Wanfang Data from the inception to January 1, 2019. Two researchers independently selected studies, collected data, and assessed the methodology quality by using Cochrane risk of bias tool. Read More

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http://dx.doi.org/10.1097/MD.0000000000014510DOI Listing
February 2019

Effectiveness and safety of fire-needle moxibustion on insomnia: Protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2019 Feb;98(7):e14509

Baoan Hospital of Traditional Chinese Medicine in Shenzhen, Shenzhen.

Background: Fire-needle moxibustion (FNM) is an ancient method of external therapy that combines acupuncture with moxibustion, and has the property of high temperature resistance. Insomnia is a major public health problem and strongly associated with a high prevalence, impact on daily life, comorbidity with other disorders, and societal costs. The clinical practice demonstrates that FNM has a therapeutic effect on insomnia. Read More

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http://dx.doi.org/10.1097/MD.0000000000014509DOI Listing
February 2019

Clinical efficacy and safety of thread-embedding acupuncture for treatment of the sequelae of Bell's palsy: A protocol for a patient-assessor blinded, randomized, controlled, parallel clinical trial.

Medicine (Baltimore) 2019 Feb;98(7):e14508

Department of Acupuncture & Moxibustion, Kyung Hee University Hospital at Gangdong, 892, Dongnam-ro, Gangdong-gu, Seoul.

Background: The sequelae of Bell's palsy cause critical problem in facial appearance, as well as social and psychological problems in the patient's life. The aim of the present study is to establish clinical evidence of thread-embedding acupuncture (TEA) in the treatment of sequelae of Bell's palsy.

Method/design: This is a patient-assessor blinded, randomized, sham-controlled trial with two parallel arms. Read More

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http://dx.doi.org/10.1097/MD.0000000000014508DOI Listing
February 2019

Association between smoking and serum uric acid in Korean population: Data from the seventh Korea national health and nutrition examination survey 2016.

Medicine (Baltimore) 2019 Feb;98(7):e14507

The aim of this study was to identify any association between serum uric acid and smoking status using data from the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-1) 2016 of the Korean population.This study used a cross-sectional design and analyzed 5609 subjects aged ≥ 19 years among 8150 participants enrolled in the KNHANES VII-1 2016. Smoking status was classified into current smokers, never smokers, and ex-smokers. Read More

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http://dx.doi.org/10.1097/MD.0000000000014507DOI Listing
February 2019

Effectiveness of extracorporeal shock-wave therapy for frozen shoulder: A protocol for a systematic review of randomized controlled trial.

Medicine (Baltimore) 2019 Feb;98(7):e14506

First Ward of Orthopedics Department, The First Hospital of Yulin, Yulin, China.

Background: This systematic review aims to explore the effectiveness and safety of extracorporeal shock-wave therapy (ESWT) for patients with frozen shoulder.

Methods: The sources of Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and Websites of Clinical Trials Registry will be searched. All databases and other sources will be searched from inception to the date of the search will be run. Read More

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http://dx.doi.org/10.1097/MD.0000000000014506DOI Listing
February 2019
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