145,724 results match your criteria Medicina Buenos Aires [Journal]


One-carbon metabolism nutrient intake and the association between body mass index and urinary arsenic metabolites in adults in the Chihuahua cohort.

Environ Int 2018 Dec 12;123:292-300. Epub 2018 Dec 12.

Environmental Science and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Curriculum in Toxicology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

Background: Exposure to inorganic arsenic (iAs) via drinking water is a serious global health threat. Various factors influence susceptibility to iAs-associated health outcomes, including differences in iAs metabolism. Previous studies have shown that obesity is associated with iAs metabolism. Read More

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December 2018

Molecular alterations in meningiomas: Literature review.

Clin Neurol Neurosurg 2018 Dec 7;176:89-96. Epub 2018 Dec 7.

Departament of Neurology, Laboratory of Molecular and Cellular Biology, LIM15, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.

Meningiomas, tumors that originate from meningothelial cells, account for approximately 30% of all new diagnoses of central nervous system neoplasms. According to the 2016 WHO classification of central nervous system tumors meningiomas are classified into three grades: I, II, and III. Past studies have shown that the risk of meningiomas recurrence is strongly correlated with the molecular profile of the tumor. Read More

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December 2018

Resveratrol promotes apoptosis through the induction of dual specificity phosphatase 1 and sensitizes prostate cancer cells to cisplatin.

Food Chem Toxicol 2018 Dec 12. Epub 2018 Dec 12.

Departamento de Bioquímica-Instituto de Investigaciones Biomédicas "Alberto Sols", Universidad Autónoma de Madrid-Consejo Superior de Investigaciones Científicas, Madrid, Spain. Electronic address:

Resveratrol is a polyphenol with chemopreventive properties against prostate cancer; however, the mechanisms underlying its actions are not completely understood. Previously, we demonstrated that DUSP1 induces apoptosis in prostate cancer cells; therefore in the present study we investigated the role of this phosphatase on resveratrol effects. Moreover, we analysed the efficiency of combined treatment of resveratrol and the chemotherapeutic drug cisplatin on cellular viability and apoptosis and its relation with DUSP1 in prostate cancer cells. Read More

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December 2018

Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide.

Gastroenterology 2018 Dec 12. Epub 2018 Dec 12.

Unit of Internal Medicine and Hepatology (UIMH), Department of Medicine - DIMED, University of Padova, Padova, Italy. Electronic address:

Background And Aims: Bacterial infections are common and life-threatening in patients with cirrhosis. Little is known about the epidemiology of bacterial infections in different regions. We performed a multicenter prospective intercontinental study to assess the prevalence and outcomes of bacterial and fungal infections in patients with cirrhosis. Read More

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December 2018

ARBOVIRUS INVESTIGATION IN PATIENTS FROM MATO GROSSO DURING ZIKA AND CHIKUNGUNYA VIRUS INTRODUTION IN BRAZIL, 2015-2016.

Acta Trop 2018 Dec 12. Epub 2018 Dec 12.

Programa de Pós-Graduação em Ciências da Saúde, Departamento de Ciências Básicas em Saúde, Faculdade de Medicina, Universidade Federal de Mato Grosso, Av. Fernando Correa da Costa, n. 2367, CCBS-I, sala 82, CEP 78060-900, Cuiabá, Mato Grosso, Brazil. Electronic address:

Arboviruses have become a major public health concern in Brazil, especially after Zika virus (ZIKV) and Chikungunya virus (CHIKV) introduction, leading to massive epidemics. We conducted an investigation of arboviruses in patients with acute febrile illness for less than five days in Mato Grosso state (MT) during the period of ZIKV and CHIKV dissemination in Brazil. To achieve that, 453 human serum samples of patients suspected of Dengue (DENV), Yellow Fever (YFV), ZIKV or CHIKV collected in health units of 31 cities of MT were subjected to RT-PCR protocols for 10 flaviviruses, 5 alphaviruses and orthobunyaviruses from Simbu serogroup, nucleotide sequencing and viral isolation. Read More

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December 2018

IgG reactivity with 40-35 kDa soluble and membrane antigen of Strongyloides venezuelensis in immunocompromised patients.

Acta Trop 2018 Dec 12. Epub 2018 Dec 12.

Laboratório de Investigação Médica (LIM/06 - Laboratório de Imunopatologia da esquistossomose), Hospital das Clínicas da Faculdade de Medicina, USP, São Paulo, Brazil; Instituto de Medicina Tropical de São Paulo, USP, São Paulo, Brazil.

Immunocompromised patients constitute a risk group for the development of severe clinical forms of human strongyloidiasis. The diagnosis of this infection is primarily performed by parasitological techniques, but with low sensitivity. Serological techniques appear as an alternative, especially with heterologous antigens use. Read More

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December 2018

A new mucin-binding lectin from the marine sponge Aplysina fulva (AFL) exhibits antibiofilm effects.

Arch Biochem Biophys 2018 Dec 12. Epub 2018 Dec 12.

Laboratório de Biotecnologia Marinha - BioMar-Lab, Departamento de Engenharia de Pesca, Universidade Federal do Ceará, Campus do Pici s/n, bloco 871, 60440-970, Fortaleza, Ceará, Brazil. Electronic address:

A new mucin-binding lectin (AFL) was isolated from the marine sponge Aplysina fulva. AFL was purified by affinity chromatography on Sepharose™ matrix. Its hemagglutinating activity was independent of divalent ions, and it was weakly inhibited by simple sugars. Read More

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December 2018

WPA Position Statement on Spirituality and Religion in Psychiatry.

Actas Esp Psiquiatr 2018 Nov 1;46(6):242-8. Epub 2018 Nov 1.

WPA Sección Sobre Religión, Espiritualidad y Psiquiatría Departamento de Teología y Religión, Universidad de Durham, Durham, UK.

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November 2018

Hyperbaric storage at variable room temperature - A new preservation methodology for minced meat compared to refrigeration.

J Sci Food Agric 2018 Dec 15. Epub 2018 Dec 15.

QOPNA, Departamento de Química, Universidade de Aveiro, Campus Universitário de Santiago, 3810-193, Aveiro, Portugal.

Hyperbaric storage (HS) at variable room temperature (RT) has been proposed as an alternative to refrigeration at atmospheric pressure (RF/AP) for food preservation and scarce information is available regarding HS effect in meat products. In this study the RT/HS effect was evaluated at 100 MPa and variable RT (≈20 °C) for minced meat preservation up to 24 h, initially for one batch, and further two other different batches were independently studied. To assess RT/HS feasibility, microbiological and physicochemical parameters were analyzed, using storage at RF/AP and variable RT/AP (≈20 °C), for comparison. Read More

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December 2018

Lichen planus: altered AIM2 and NLRP1 expression in skin lesions and defective activation in peripheral blood mononuclear cells.

Clin Exp Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Investigation in Medicine, LIM-56, Department of Dermatology, Tropical Medicine Institute of São Paulo, University of São Paulo Medical School, São Paulo, Brazil.

Background: Lichen planus (LP) is an inflammatory skin disease with unknown aetiology. Activation by pathogen-associated molecular patterns or environmental stimuli may activate some components of inflammasomes that contribute to the inflammatory process in LP lesions.

Aim: To characterize the inflammasomes in skin lesions and peripheral blood mononuclear cells (PBMCs) of patients with LP under Toll-like receptor (TLR) activation. Read More

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December 2018

Stochastic Modeling and Simulation of Viral Evolution.

Bull Math Biol 2018 Dec 14. Epub 2018 Dec 14.

Departamento de Informática em Saúde, Laboratório de Biocomplexidade e Genômica Evolutiva, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

RNA viruses comprise vast populations of closely related, but highly genetically diverse, entities known as quasispecies. Understanding the mechanisms by which this extreme diversity is generated and maintained is fundamental when approaching viral persistence and pathobiology in infected hosts. In this paper, we access quasispecies theory through a mathematical model based on the theory of multitype branching processes, to better understand the roles of mechanisms resulting in viral diversity, persistence and extinction. Read More

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December 2018

Author Correction: Comparison of 1D and 3D Models for the Estimation of Fractional Flow Reserve.

Sci Rep 2018 Dec 14;8(1):17962. Epub 2018 Dec 14.

National Laboratory for Scientific Computing, LNCC/MCTIC, Av. Getúlio Vargas, 333, Petrópolis-RJ, 25651-075, Brazil.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. Read More

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December 2018

The antitumor drugs trabectedin and lurbinectedin induce transcription-dependent replication stress and genome instability.

Mol Cancer Res 2018 Dec 14. Epub 2018 Dec 14.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla

R-loops are a major source of replication stress, DNA damage and genome instability, which are major hallmarks of cancer cells. Accordingly, growing evidence suggests that R-loops may also be related to cancer. Here we show that R-loops play an important role in the cellular response to trabectedin (ET743), an anticancer drug from marine origin and its derivative lurbinectedin (PM01183). Read More

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December 2018

Is hepatitis A virus infection under control? lessons in the application of viral sequencing for the development of vaccination schemes in emergency situations.

Authors:
Nora A Fierro

EBioMedicine 2018 Dec 11. Epub 2018 Dec 11.

Unidad de Inmunovirologia, Servicio de Biologia Molecular en Medicina, Hospital Civil de Guadalajara ″Fray Antonio Alcalde″, Mexico; Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico. Electronic address:

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December 2018

[Update on human head lice].

Semergen 2018 Dec 11. Epub 2018 Dec 11.

Medicina Familiar y Comunitaria, Hospital Universitari Mútua Terrassa / CAP Valldoreix, Terrassa, España. Electronic address:

Head lice is a common condition, and it causes great concern in parents of the affected child. Resistance to the most common treatment has been reported recently, due to an indiscriminate use. A review is presented on this condition and its available treatments. Read More

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December 2018

[Malaria in an immigrant patient traveling back to his country].

Semergen 2018 Dec 11. Epub 2018 Dec 11.

Medicina Familiar y Comunitaria, Centro de Salud Panaderas, Fuenlabrada, Madrid, España.

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December 2018

Cutaneous metastasis from Hürthle cell follicular thyroid carcinoma.

Rev Esp Med Nucl Imagen Mol 2018 Dec 11. Epub 2018 Dec 11.

Servicio de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, España.

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December 2018

PET/CT in uterine tumors. Progressing on the right direction.

Rev Esp Med Nucl Imagen Mol 2018 Dec 11. Epub 2018 Dec 11.

Coordinadora de la Unidad de Ginecología Oncológica, Servicio de Ginecología, Hospital de Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, España.

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December 2018

YY1 negatively regulates the XAF1 gene expression in prostate cancer.

Biochem Biophys Res Commun 2018 Dec 11. Epub 2018 Dec 11.

Laboratorio de Investigacion en Patologia Experimental, Hospital Infantil de Mexico Federico Gomez, 06720, Mexico City, Mexico; Division de Investigacion, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, 04510, Mexico City, Mexico. Electronic address:

XAF1 is a tumor suppressor gene with low or absent expression in cancer. Since transcriptional reactivation or ectopic-mediated expression of XAF1 inhibits tumor growth, it is of great interest to elucidate the molecular mechanisms leading to XAF1 silencing. YY1 is a transcription factor that acts as a repressor or an activator to modulate several cancer-associated cellular processes. Read More

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December 2018

Association between Polymorphisms in Inflammatory Response-Related Genes and the Susceptibility, Progression and Prognosis of the Diffuse Histological Subtype of Gastric Cancer.

Genes (Basel) 2018 Dec 13;9(12). Epub 2018 Dec 13.

Centro de Investigacao Translacional em Oncologia (LIM24), Departamento de Radiologia e Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Faculdade de Medicina da Universidade de Sao Paulo (FMUSP), Sao Paulo 01246-000, Brazil.

The chronic inflammatory microenvironment and immune cell dysfunction have been described as critical components for gastric tumor initiation and progression. The diffuse subtype is related to poor clinical outcomes, pronounced inflammation, and the worst prognosis. We investigated the association of polymorphisms in inflammatory response-related genes (, , , , , , , , , , and ) with gastric cancer susceptibility, progression and prognosis in a Brazilian sample, focusing on the diffuse subtype. Read More

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December 2018

Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome.

Nutrients 2018 Dec 13;10(12). Epub 2018 Dec 13.

Dipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy.

There is a mechanistic link between the gut-derived metabolite trimethylamine-N-oxide (TMAO) and obesity-related diseases, suggesting that the TMAO pathway may also be linked to the pathogenesis of obesity. The Visceral Adiposity Index (VAI), a gender-specific indicator of adipose dysfunction, and the Fatty Liver Index (FLI), a predictor of non-alcoholic fatty liver disease (NAFLD), are early predictors of metabolic syndrome (MetS). In this cross-sectional observational study, we investigated TMAO levels in adults stratified according to Body Mass Index (BMI) and the association of TMAO with VAI and FLI. Read More

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December 2018

Activation of and in Transgenic Mouse Embryonic Stem Cells Increases Differentiation into Neural Crest Derivatives.

Int J Mol Sci 2018 Dec 13;19(12). Epub 2018 Dec 13.

Instituto de Fisiología Celular-Neurociencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, México.

The neural crest (NC) comprises a multipotent cell population that produces peripheral neurons, cartilage, and smooth muscle cells, among other phenotypes. The participation of and when expressed in mouse embryonic stem cells (mESCs) undergoing NC differentiation is unexplored. In this work, we generated stable mESCs transfected with constructs encoding chimeric proteins in which the ligand binding domain of glucocorticoid receptor (GR), which is translocated to the nucleus by dexamethasone addition, is fused to either (HGR) or (MGR), as well as double-transgenic cells (HGR+MGR). Read More

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December 2018

In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic F127-based polymeric micelle system against Leishmania amazonensis infection.

Biomed Pharmacother 2019 Jan 5;109:779-787. Epub 2018 Nov 5.

Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, 30130-100, Minas Gerais, Brazil; Departamento de Patologia Clínica, COLTEC, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Minas Gerais, Brazil. Electronic address:

New therapeutic strategies against leishmaniasis are desirable, since the treatment against disease presents problems, such as the toxicity, high cost and/or parasite resistance. As consequence, new antileishmanial compounds are necessary to be identified, as presenting high activity against Leishmania parasites, but low toxicity in mammalian hosts. Flau-A is a naphthoquinone derivative recently showed to presents an in vitro effective action against Leishmania amazonensis and L. Read More

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January 2019

Chrysin (5,7-dihydroxyflavone) exerts anxiolytic-like effects through GABA receptors in a surgical menopause model in rats.

Biomed Pharmacother 2019 Jan 30;109:2387-2395. Epub 2018 Nov 30.

Facultad de Ciencias Químicas, Universidad Veracruzana, Orizaba, Veracruz, Mexico.

The present study investigated the effects of the flavonoid chrysin (5,7-dihydroxyflavone) on anxiety-like behavior in rats in a model of surgical menopause and evaluated the participation of γ-aminobutyric acid-A (GABA) receptors in these actions. At 12 weeks post-ovariectomy, the effects of different doses of chrysin (0.5, 1, 2, and 4 mg/kg) were evaluated in the elevated plus maze, light/dark test, and locomotor activity test, and comparisons were made with the clinically effective anxiolytic diazepam. Read More

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January 2019

Low serum levels of CCL2 are associated with worse prognosis in patients with Acute Coronary Syndrome: 2-year survival analysis.

Biomed Pharmacother 2019 Jan 12;109:1411-1416. Epub 2018 Nov 12.

Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Brazil.

Inflammation is very important in Acute Coronary Syndrome (ACS) as well as in cardiac remodeling after an acute myocardial infarction (MI). Our study examined the prognostic value of Chemokine (C-C motif) ligand 2 (CCL2) in patients with ACS in the ERICO (Strategy of Registry of Acute Coronary Syndrome) study. We evaluated serum samples from 803 patients. Read More

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January 2019

The role of neurogenesis in neurorepair after stroke.

Semin Cell Dev Biol 2018 Dec 11. Epub 2018 Dec 11.

Departamento de Farmacologia, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil. Electronic address:

Stroke consists of an abrupt reduction of cerebral blood flow resulting in hypoxia that triggers an excitotoxicity, oxidative stress, and neuroinflammation. After the ischemic process, neural precursor cells present in the subventricular zone of the lateral ventricle and subgranular zone of the dentate gyrus proliferate and migrate towards the lesion, contributing to the brain repair. The neurogenesis is induced by signal transduction pathways, growth factors, attractive factors for neuroblasts, transcription factors, pro and anti-inflammatory mediators and specific neurotransmissions. Read More

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December 2018
1 Read

Mortality of patients with chronic disease: an increasing problem.

J Pediatr (Rio J) 2018 Dec 11. Epub 2018 Dec 11.

Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria, Pediatric Intensive Care Unit, Madrid, Spain; Maternal and Child Health and Development Network, RETICS funded by the PN I+D+I 2013-2016 (Spain), ISCIII-Sub-Directorate General for Research Assessment and Promotion and the European Regional Development Fund (ERDF), Spain; Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Salud Pública y Maternoinfantil, Madrid, Spain. Electronic address:

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December 2018

Postnatal management of growth failure in children born small for gestational age.

J Pediatr (Rio J) 2018 Dec 11. Epub 2018 Dec 11.

Universidade Federal da Bahia, Faculdade de Medicina, Pediatria, Salvador, BA, Brazil.

Objectives: To discuss the etiology and growth consequences of small size at birth and the indications, effects, and safety of biosynthetic growth hormone therapy in children born small for gestational age.

Source Of Data: A comprehensive and non-systematic search was carried out in the PubMed, LILACS, and SciELO databases from 1980 to the present day, using the terms "small for gestational age," "intrauterine growth restriction," and "growth hormone". The publications were critically selected by the authors. Read More

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December 2018

Sentinel hospital-based surveillance for norovirus infection in children with gastroenteritis between 2015 and 2016 in Italy.

PLoS One 2018 14;13(12):e0208184. Epub 2018 Dec 14.

Dipartimento di Scienze Biomediche e Oncologia Umana, Università Aldo Moro di Bari, Bari, Italy.

Noroviruses are one of the leading causes of gastro-enteric diseases worldwide in all age groups. Novel epidemic noroviruses with GII.P16 polymerase and GII. Read More

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December 2018
1 Read

Combined therapy with levothyroxine and liothyronine for hypothyroidism.

Medwave 2018 Dec 14;18(8):e7376. Epub 2018 Dec 14.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: The usual supplementation for hypothyroidism is based on monotherapy with levothyroxine. However, some patients persist with symptoms attributable to the deficit of thyroid hormone. It has been suggested that the a combined treatment with liothyronine and levothyroxine would provide a greater benefit. Read More

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December 2018

Topical tranexamic acid for spontaneous epistaxis.

Medwave 2018 Dec 10;18(8):e7372. Epub 2018 Dec 10.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Otorrinolaringología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: Spontaneous epistaxis is one of the most frequent problems in emergency services. New treatment alternatives have emerged, including topical tranexamic acid. However, there is controversy about the actual efficacy of this alternative. Read More

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December 2018

Laparoscopic versus open appendectomy for complicated appendicitis.

Medwave 2018 Dec 11;18(8):e7370. Epub 2018 Dec 11.

Proyecto Epistemonikos, Santiago, Chile; Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile; Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: The treatment of acute appendicitis using laparoscopy reduces the risk of wound infection, hospitalization time and return to normal activity. However, it increases the risk of intra-abdominal abscess, which is one the main complications of complicated appendicitis.

Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More

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December 2018

[Preliminary results of a cognitive survey among the members of the Italian Medical Radiation Protection Society(AIRM): from characterization of the professional activity to identification of training needs].

G Ital Med Lav Ergon 2018 Dec;40(4):224-247

Consiglio Nazionale delle Ricerche and Consiglio Direttivo AIRM.

Objectives: For several decades, the Italian Association of Medical Radioprotection (AIRM) is engaged in the promotion of scientific, technical, and methodological knowledge in the field of medical radioprotection.

Methods: Starting from the results of the previous study conducted in 2013, AIRM has carried out a new survey among its members. This survey was carried out through a self-administered questionnaire to be completed online on a platform set up on the association's website. Read More

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December 2018

[Manual handling, job fitness, and musculoskeletal disorders in the Sondrio hospital (Italy) healthcare workers.]

G Ital Med Lav Ergon 2018 Dec;40(4):203-207

Dipartimento di Sanità Pubblica, Medicina Sperimentale e Forense, Sezione di Medicina del Lavoro, Università degli Studi di Pavia and Unità Operativa di Medicina del Lavoro, Istituti Clinici Scientifici Maugeri IRCCS, Pavia.

Objectives: Musculo-skeletal disorders (MSD) are a large group of locomotor system pathologies with multifactorial etiology. Healthcare professionals are often exposed to biomechanical overload of the spine and upper limb, for example during patient handling, and represent a working population at risk.

Methods: In order to acquire further knowledge on this subject, we conducted a cross-sectional study (year 2016) among healthcare workers (excluding physicians) of the Sondrio Hospital (Italy), investigating the correlations between manual handling, MDS and job fitness. Read More

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December 2018

[Biological risk in agriculture and construction workplaces: a survey on perception, knowledge and prevention measures.]

G Ital Med Lav Ergon 2018 Dec;40(4):195-202

Cattedra di Igiene, Dipartimento di Medicina e Scienze per la Salute "Vincenzo Tiberio", Università degli Studi del Molise.

Objectives: Despite the potential presence in many workplaces, biological risk is little known and largely underestimated, except in healthcare environments. Objectives: To evaluate perception, knowledge and behaviors adopted for protection and prevention of biological risk, related also to the occupational activity, among construction and agricultural workers.

Methods: Workers were recruited at farms and construction companies of Molise Region, Central Italy, which were visited within the surveillance activities planned by local institutions. Read More

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December 2018

[Social determinants of the health of international migrant children in Chile: qualitative evidence.]

Salud Publica Mex 2018 Sep-Oct;60(5):566-578

Programa de Estudios Sociales en Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo. Santiago, Chile.

Objective: To explore the social determinants of health (SDH) of international migrant children, from the perceptions of caregivers, health workers and local authorities in eight municipalities in Chile.

Materials And Methods: A secondary analysis of data was conducted from a qualitative study that took place between 2014 and 2017. The original study involved semi-structured interviews and focus groups. Read More

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[Food Insecurity Experience Scale (FIES) in Colombia, Guatemala, and México.]

Salud Publica Mex 2018 Sep-Oct;60(5):510-519

Hospital Universitario Nacional de Colombia, Facultad de Medicina, Universidad Nacional de Colombia. Bogotá. Colombia.

Objective: To compare the psychometric characteristics of the Food Insecurity Experience Scale (FIES) and the grade of similitude or difference among Colombia, Guatemala, and Mexico during three years.

Materials And Methods: Psychometric comparison using the Rasch model to calculate the relative severity of each item in FIES, INFIT and contrast in the Differential Functioning of Items (c-DIF).

Results: The majority of items showed a relative severity corresponding to the theoretical construct and acceptably fit the model (INFIT=0. Read More

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August 2017
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[Acute kidney injury as a risk marker for hospital readmission: a single-center pilot study in the general population of the Parma area].

G Ital Nefrol 2018 Dec;35(6)

Unità di Fisiopatologia dell'Insufficienza Renale Acuta e Cronica - Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.

Acute Kidney Injury (AKI) is an important issue for the healthcare system, as it is associated with high mortality and increased risk of readmission, with consequent elevated healthcare resource utilization. We investigated the incidence of AKI based on the examination of the discharge cards of all patients admitted between January 1 2011 and December 31 2015 at the Parma University Hospital, as well as the frequency and type of 30-day hospital readmission in the patients discharged with a first AKI diagnosis (index admission). The mean pooled 5-year incidence of AKI was 2. Read More

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December 2018

[FSGS collapsing variant during anabolic steroid abuse: Case Report].

G Ital Nefrol 2018 Dec;35(6)

UO Nefrologia e Dialisi AUSL Romagna Ospedale Infermi Rimini.

Anabolic Androgenic Steroids (AAS) is an hormone family whose use has considerably increased among body-builders during the last decades. The AAS abuse, especially associated with other drugs or nutritional supplements and protein loads, may cause a variety of pathologies to several organs with a mechanism related to dosage, timing and substance. The kidney is the main metabolizer of these drugs and it can be acutely or chronically damaged with ESKD. Read More

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December 2018

[PHYSICAL, CHEMICAL AND MORPHOLOGICAL URINE EXAMINATION: RECOMMENDATIONS FOR THE POST ANALYTICAL PHASE FROM THE INTERDISCIPLINARY URINALYSIS GROUP (GIAU)].

G Ital Nefrol 2018 Dec;35(6)

Cattedra Nefrologia Università degli Studi di Bari-Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari.

With these recommendations the Interdisciplinary Urinalysis Group (GIAU) aims to stimulate the following aspects : improvement and standardization of the post analytical approach to physical, chemical and morphological urine examination (ECMU); emphasize the value added to ECMU by selection of clinically significant parameters, indication of analytical methods, of units of measurement, of reference values; improvement of interpretation of dip stick urinalysis with particular regard to the reconsideration of the diagnostic significance of the evaluated parameters together with an increasing awareness of the limits of sensitivity and specificity of this analytical method. Accompanied by the skills to propose and carry out in-depth investigations with analytical methods that are more sensitive and specific;increase the awareness of the importance of professional skills in the field of urinary morphology and their relationships with the clinicians. through the introduction, in the report, of descriptive and interpretative comments depending on the type of request, the complexity of the laboratory, the competence of the pathologist;implement a policy of evaluation of the analytical quality by using, in addition to traditional internal and external controls, a program for the evaluation of morphological competence. Read More

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December 2018

[Methodology for determining workforce in health nephrologic unit in ITALY. Update of lows].

G Ital Nefrol 2018 Dec;35(6)

Membro del Direttivo SIN, esperto di organizzazione sanitaria, ex responsabile controllo di gestione ospedale di Perugia, ex coordinatore governo clinico SIN.

Nephrology continues to be in transition. While rates of kidney diseases and injury continue to rise, changes in the general health care system and the delivery of kidney care make it unclear how increases in need will be translated into demand for nephrologists. The changes in the delivery system also raise questions as to the future roles and career paths for nephrologists. Read More

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December 2018

[Parathyroid carcinoma: diagnosis by a femur fracture].

Acta Ortop Mex 2018 Jul-Aug;32(4):229-233

Departamento de Anatomopatología del Hospital Ángeles León. León, Guanajuato. México.

Background: Carcinoma of the parathyroid gland (PC) described by De Quervain since 1909, it represents the least common neoplasm, with an incidence of 1,25/10,000,000 peoples. It has been reported approximately 1,000 cases of CP in world literature. There are two series in Mexico, one of eight patients and other with four cases. Read More

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December 2018
1 Read

A giant and atypical port-wine stain with facial deformity.

J Dtsch Dermatol Ges 2018 Dec 14. Epub 2018 Dec 14.

Servicio de Dermatología Hospital Universitario "Dr. José E. González", Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, México.

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December 2018

Molecular epidemiology of MRSA in the Brazilian primary health care system.

Trop Med Int Health 2018 Dec 14. Epub 2018 Dec 14.

Departamento de Microbiologia e Imunologia, Instituto de Biociências de Botucatu, Univ Estadual Paulista, Botucatu, Brazil.

Objective: To evaluate the molecular epidemiology and to georeference Staphylococcus aureus isolated from wounds and nares of patients seen at Basic Health Units (BHUs) of a Brazilian city.

Methods: Observational, cross-sectional study conducted from 2010 to 2013. A total of 119 S. Read More

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December 2018

Relationships among general health, job satisfaction, work engagement and job features in nurses working in a public hospital: A cross-sectional study.

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

Multidisciplinary Group of Integral Cares (GIMCI), Av. Menéndez Pidal, s/n, 14004, Córdoba, Spain.

Aim And Objective: To describe relations among health, job satisfaction, work engagement and job features in Spanish nurses working in a public hospital.

Background: It has been established that nursing staff health affects the quality of their work and is associated with job satisfaction, work engagement and different job features. Understanding the relationships among these variables could provide useful information to improve staff performance and prevent work-related illnesses. Read More

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December 2018

Acid Sensing Ion Channel 2: a new potential player in the pathophysiology of multiple sclerosis.

Eur J Neurosci 2018 Dec 14. Epub 2018 Dec 14.

Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.

Acid Sensing Ion Channel (ASICs) are proton-gated channels involved in multiple biological functions such as: pain modulation, mechanosensation, neurotransmission and neurodegeneration. Earlier, we described the genetic association, within the Nuoro population, between multiple sclerosis (MS) and rs28936, located in ASIC2 3'UTR. Here we investigated the potential involvement of ASIC2 in MS inflammatory process. Read More

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December 2018
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A confusing "white cell count" - circulating micromegakaryocytes in post-thrombocythemia myelofibrosis.

Am J Hematol 2018 Dec 14. Epub 2018 Dec 14.

Department of Haematology, Centre for Haematology, St Mary's Hospital Campus of Imperial College London Faculty of Medicine, St Mary's Hospital, Praed Street, London W2 1NY, UK.

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December 2018

Thermoalgesic stimuli induce prepulse inhibition of the blink reflex and affect conscious perception in healthy humans.

Psychophysiology 2018 Dec 14:e13310. Epub 2018 Dec 14.

EMG Unit, Neurology Department, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.

All sensory stimuli produce transient excitability changes in various central nervous system circuits. One example is prepulse inhibition (PPI), which is the inhibition generated by a preceding weak stimulus (prepulse) over the reflex response to a subsequent suprathreshold stimulus. The PPI is a ubiquitous phenomenon, common to many different sensory modalities. Read More

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December 2018

Waist circumference and abdominal volume index are the strongest anthropometric discriminators of metabolic syndrome in Spanish adolescents.

Eur J Clin Invest 2018 Dec 14:e13060. Epub 2018 Dec 14.

Department of Nursing, University of Granada, Av. Ilustración, 60, 18016, Granada, Spain.

Background: Waist circumference has been suggested as predictor for metabolic syndrome (MetS) in adolescents but it has not been compared with newly proposed anthropometric indexes. This study aimed to disclose the capacity of ten classic and novel anthropometric indexes to discriminate by the presence of MetS in this young population.

Materials And Methods: A cross-sectional study was performed on 981 adolescents (13. Read More

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December 2018