1,796 results match your criteria Medical Principles and Practice [Journal]


Evaluation of the Relationship Between Type II Diabetes Mellitus and the Prevalence of Apical Periodontitis in Root-Filled Teeth Using Cone Beam Computed Tomography: An Observational Cross-Sectional Study.

Med Princ Pract 2019 Apr 19. Epub 2019 Apr 19.

Objective: This study aimed to investigate the prevalence of apical periodontitis (AP) in type II diabetic (DM) patients with either optimal glycemic control (OGC) or poor glycemic control (PGC) compared with nondiabetics using cone-beam computed tomography (CBCT).

Subjects And Methods: The periapical status of 75 teeth with adequate root canal treatment performed at least one year ago that could be visualized in the field of view of CBCT images of 43 DM patients (29 females, 14 males) were compared with a control group consisting of 162 teeth of 86 nondiabetics (56 females, 30 males). In addition, the DM group was divided into subgroups according to the patients' mean glycated hemoglobin level as either having OGC or PGC. Read More

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http://dx.doi.org/10.1159/000500472DOI Listing

Intravitreal Ranibizumab Injection for the Treatment of Retinopathy of Prematurity.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: To evaluate the efficacy of a single injection of 0.3 mg of intravitreal ranibizumab for the treatment of retinopathy of prematurity.

Methods: We conducted this retrospective case series study in King Abdul Aziz Medical City, Riyadh, Saudi Arabia. Read More

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http://dx.doi.org/10.1159/000500310DOI Listing
April 2019
2 Reads

Phenotypic and Genotypic characterization of ESBLs, AmpC and Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli Isolates.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: Drug resistance among gram-negative bacteria is a worldwide challenge. Due to the importance of drug-resistant Klebsiella pneumoniae and Escherichia coli strains in hospital-acquired infections, we aimed to determine the phenotypic and genotypic characteristics of ESBLs, AmpC and Carbapenemase-producing isolates, obtained from hospitalized patients in Tehran and Ilam, Iran.

Materials And Methods: In total, 90 isolates of K. Read More

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http://dx.doi.org/10.1159/000500311DOI Listing

The Effect of Gonadotropin-Releasing Hormone Analogue on Final Adult Height in Children with Idiopathic Short Stature.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objective: Assess final adult height (FAH) in children with short stature treated with gonadotropin-releasing hormone analogue (GnRHa).

Methods: All patients with idiopathic short stature (ISS) with normally timed puberty and a Tanner stage between 2-3, who achieved their final adult height (FAH) between 2005 and 2015, were included in this clinical historical cohort study. Height gain, FAH and, mid-parental height of 28 children with ISS who received GnRHa treatment for 1. Read More

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http://dx.doi.org/10.1159/000499929DOI Listing
April 2019
1 Read

Diffuse Coronary Artery Fistula Leading to Syncope and Treated by Transcatheter Coil Occlusion and a Defibrillator: A Case Report.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: Coronary artery fistulas connecting coronary arteries to cardiac cavities are rare but clinically significant anomalies.

Clinical Presentation And Intervention: A 47-year-old male patient presented with syncope. Left ventricular dysfunction was detected on echocardiography. Read More

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http://dx.doi.org/10.1159/000500309DOI Listing
April 2019
1 Read

Ultrasound-Guided Continuous Femoral Nerve Block with Dexmedetomidine Combined with Low Concentrations of Ropivacaine for Postoperative Analgesia in Elderly Knee Arthroplasty.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: This study aims to investigate the clinical effect of dexmedetomidine (DEX) combined with low concentrations of ropivacaine in ultrasound-guided continuous femoral nerve block for postoperative analgesia in elderly patients with total knee arthroplasty (TKA).

Materials And Methods: Patients were divided into three groups: group C, group D1 and group D2. For postoperative analgesia, patients in group C were given 0. Read More

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http://dx.doi.org/10.1159/000500261DOI Listing

NT-proBNP and Echocardiographic Parameters in Liver Cirrhosis - Correlations with Disease Severity.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

determined. Liver disease severity in patients with cirrhosis was established by Child-Pugh class, MELD score and presence/absence of ascites. Results: Plasma levels of NT-proBNP were significantly higher in cirrhotic patients than in the healthy subjects. Read More

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http://dx.doi.org/10.1159/000499930DOI Listing
April 2019
2 Reads

Assessing HIV/AIDS Knowledge, Awareness and Attitudes among Senior High School Students in Kuwait.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: An estimated 1.8 million individuals worldwide became newly infected with human immunodeficiency virus (HIV) in 2016, which amounts to 5,000 new infections per day. This includes 160,000 children. Read More

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http://dx.doi.org/10.1159/000500307DOI Listing
April 2019
1 Read

Coronally Repositioned Flap with Bioresorbable Collagen Membrane for Miller's Class I and II Recession defects - A Case Series.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objective: Gingival recession is one of the most common aesthetic and functional concerns associated with periodontal tissues. Several techniques have been described in order to cover the exposed root surface. The aim of the present study was to evaluate the efficacy of recession coverage using coronally repositioned flap in conjunction with bioresorbable collagen membrane. Read More

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http://dx.doi.org/10.1159/000500308DOI Listing

Serum Adropin Levels are Reduced in Adult Patients with Nonalcoholic Fatty Liver Disease.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Objectives: Adropin is a novel marker of metabolic syndrome and insulin resistance. The aim of this study was to explore the association of serum adropin levels with hepatosteatosis among adult patients.

Material And Method: Serum biochemical parameters including liver and renal function tests, insulin levels and serum adropin levels were compared between adult patients with nonalcoholic fatty liver disease (NAFLD) and healthy control cases. Read More

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http://dx.doi.org/10.1159/000500106DOI Listing
April 2019
1 Read

Laparoscopy First Approach in Acute Care Surgery.

Med Princ Pract 2019 Apr 16. Epub 2019 Apr 16.

Introduction: The use of laparoscopic management as a first choice for the treatment of duodenal perforation is gaining ground but is not routine in many centers. In this report we aim to report our experience with laparoscopy as the first approach for the repair of duodenal perforation.

Materials And Methods: This is a retrospective review of patients during our initial experience with the use of laparoscopy for the treatment of duodenal perforation between 2009 and 2013. Read More

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http://dx.doi.org/10.1159/000500107DOI Listing
April 2019
2 Reads

Prognosis of Primary Osteosarcoma in Elderly Patients: A Comparison between Young and Elderly Patients.

Med Princ Pract 2019 Apr 17. Epub 2019 Apr 17.

Objectives: Osteosarcoma is the most common malignant bone tumor in childhood. Although a poorer prognosis has been described in older patients, few reports have focused solely on primary osteosarcoma. We evaluated the clinical features of elderly patients with primary osteosarcoma. Read More

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http://dx.doi.org/10.1159/000500404DOI Listing
April 2019
1 Read

Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy.

Med Princ Pract 2019 Mar 22. Epub 2019 Mar 22.

Objective
We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma (GN) during the diagnostic work up of alopecia areata (AA).
Clinical Presentation and Intervention
Laboratory investigations revealed only vitamin D deficiency. Laparoscopic adrenalectomy was performed and GN was confirmed histologically. Read More

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http://dx.doi.org/10.1159/000499755DOI Listing
March 2019
2 Reads
1.113 Impact Factor

Rapid Changes of Thyroid Function in a Young Woman with Autoimmune Thyroid Disease.

Med Princ Pract 2019 Mar 22. Epub 2019 Mar 22.

Objective
A conversion from Hashimoto's thyroiditis (HT) to Graves' disease (GD) and vice versa leads to diagnostic and therapeutic challenges.
Clinical Presentation and Intervention
A 30-year old woman presented with overt hyperthyroidism and negative thyroid-stimulating hormone receptor antibodies (TRAbs). Since hashitoxicosis was assumed, the patient was treated with propranolol. Read More

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http://dx.doi.org/10.1159/000499754DOI Listing
March 2019
1 Read

Serum Albumin and Future Risk of Hip, Humeral, and Wrist Fractures in Caucasian Men: New Findings from a Prospective Cohort Study.

Med Princ Pract 2019 Mar 21. Epub 2019 Mar 21.

Objective: Low serum albumin concentration is associated with poor health outcomes, but its relationship with the risk of fractures has not been reliably quantified. We aimed to assess the prospective association of serum albumin with the risk of fractures in a general population.

Subjects And Methods: Baseline serum albumin concentrations were measured in 2,245 men aged 42-61 years in the Kuopio Ischemic Heart Disease study. Read More

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http://dx.doi.org/10.1159/000499738DOI Listing
March 2019
2 Reads
1.113 Impact Factor

Forensic Epigenetic Analysis: The Path Ahead.

Med Princ Pract 2019 03 12. Epub 2019 Mar 12.

Unlike DNA fingerprinting which scores for differences in the genome that are phenotype neutral, epigenetic variations are gaining importance in forensic investigations. Methylation of DNA has a broad range of effects on the lifestyle, health status and physical appearance of individuals. DNA methylation profiling of forensic samples is useful in the determination of the cell or tissue type of DNA source and also for estimation of age. Read More

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http://dx.doi.org/10.1159/000499496DOI Listing
March 2019
3 Reads

Need for De-Prescribing in Hospital Elderly Patients Discharged with Limited Life Expectancy: The REPOSI Study.

Med Princ Pract 2019 Mar 20. Epub 2019 Mar 20.

Objective: Older people approaching the end of life are at high risk for adverse drug reactions. Approaching end of life should change the therapeutic aims, triggering a reduction in the number of drugs. The main aim of this study was to describe the preventive and symptomatic drug treatments prescribed to patients discharged from internal medicine and geriatric wards, with limited life expectancy. Read More

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http://dx.doi.org/10.1159/000499692DOI Listing
March 2019
4 Reads

Diagnosis of Eosinophilic Esophagitis in Children - A Serbian Single Center Experience from 2010 to 2017.

Med Princ Pract 2019 Mar 19. Epub 2019 Mar 19.

Objectives: The aim of this study was to assess the epidemiological, clinical, endoscopic and pathohistological characteristics of pediatric eosinophilic esophagitis (EoE) in Serbia.

Method: All children aged 0 to 18 diagnosed with EoE in the period between 2010 and 2017, at the University Children's Hospital in Belgrade, Serbia, were retrospectively enrolled.

Results: EoE was diagnosed in 35 children (12. Read More

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http://dx.doi.org/10.1159/000499657DOI Listing
March 2019
2 Reads

Prenatal Inflammation Dampens Neurogenesis and Enhances Serotonin Transporter Expression in the Hippocampus of Adult Female Rats.

Med Princ Pract 2019 Mar 19. Epub 2019 Mar 19.

Objective:
Prenatal exposure to LPS dampens hippocampal neurogenesis. This effect is associated with increased anxiety-like behavior in adult offspring. Furthermore, blocking serotonin transporters (SERT) promotes adult neurogenesis. Read More

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http://dx.doi.org/10.1159/000499658DOI Listing

Female Physicians Leading Health Care in the Arab World.

Med Princ Pract 2019 Mar 15. Epub 2019 Mar 15.

Background And Objectives: A global trend in female leadership roles in the medical profession is on the rise, and females have been taking up leadership roles in varying and increasing levels. This study aims to identify changes in trends in the medical field in terms of gender in the last decade in Kuwait.

Methods: A case study was conducted, in which data on leadership positions in Kuwait's government hospitals were obtained from hospital registries. Read More

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http://dx.doi.org/10.1159/000499592DOI Listing
March 2019
1 Read

HLA Haplotype Frequencies and Genetic Profiles of the Kuwaiti Population.

Med Princ Pract 2019 Mar 15. Epub 2019 Mar 15.

Objective: The aim of this study was to assess the HLA haplotype frequencies and genetic profiles of the Kuwaiti population.

Materials And Methods: Whole venous blood was obtained from 595 healthy, unrelated Kuwaiti volunteers. The study population was genotyped for HLA class I (HLA-A, HLA-B, and HLA-C) and class II (HLA-DRB1 and HLA-DQB1) loci using sequence-specific oligonucleotide (SSO) probe-based hybridization and high resolution HLA genotyping. Read More

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http://dx.doi.org/10.1159/000499593DOI Listing
March 2019
9 Reads

Oral Health Status of Kuwaiti Children with a History of Chronic Liver Disease.

Med Princ Pract 2019 Mar 15. Epub 2019 Mar 15.

Objective: To investigate the oral health status and dental manifestations of children with a history of chronic liver disease (CLD) compared to healthy children.

Subjects And Methods: Twenty children (15 boys, 5 girls) with history of CLD were compared to twenty healthy controls, matched for age and gender. Clinical examination was carried out by the same dentist. Read More

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http://dx.doi.org/10.1159/000499594DOI Listing
March 2019
5 Reads

Thyroid Nodules are More Prevalent in Subjects with Colon Polyps, Independent of Insulin Resistance.

Med Princ Pract 2019 Mar 13. Epub 2019 Mar 13.

Objective: Colorectal polyps and thyroid nodules are common disorders linked to hyperinsulinemia and metabolic syndrome (Mets). The direct association between these two diseases is not clear. We aimed to analyze the prevalence of thyroid nodules in subjects with and without colorectal polyps. Read More

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http://dx.doi.org/10.1159/000499527DOI Listing
March 2019
1 Read

Platelet Rich Plasma Diffusion in Achilles Tendon: Relationship with Therapeutic Outcomes.

Med Princ Pract 2019 Mar 13. Epub 2019 Mar 13.

Objective: The therapeutic efficacy of platelet-rich plasma in the treatment of Achilles tendinopathy is controversial. Among the variables which can explain the discrepant results, little attention has been paid to the distribution of platelet-rich plasma inside the tendon. The aim of the present study was to evaluate whether this factor is related to the clinical outcome of treatment. Read More

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http://dx.doi.org/10.1159/000499528DOI Listing
March 2019
1 Read

An Atypical Presentation of Raynaud's Disease.

Med Princ Pract 2019 Mar 12. Epub 2019 Mar 12.

Objective: A 57-year-old female with a 33-year history of constant hand discoloration and paronychia had undergone multiple evaluations with a failure to find a diagnosis. She continues to undergo an evolving treatment regimen and diagnostic workup in an effort to find a long-eluded diagnosis.

Clinical Presentation: She began to develop superficial ulcerations over the proximal phalanx of her fingers, often pruritic and erythematous, with pain and edema. Read More

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http://dx.doi.org/10.1159/000499495DOI Listing

FINDRISC Modified for Latin America As A Screening Tool For Persons With Impaired Glucose Metabolism In Ciudad Bolivar, Venezuela.

Med Princ Pract 2019 Mar 11. Epub 2019 Mar 11.

Objective: The Finnish Diabetes Risk Score (FINDRISC) includes anthropometric, metabolic, and lifestyle factors that predict type 2 diabetes mellitus (T2DM). The objective of this study was to evaluate the FINDRISC modified for Latin America (LA-FINDRISC) as a screening tool for persons with impaired glucose metabolism in Ciudad Bolívar - Venezuela.

Methods: Subjects aged between 18-70 years of both sexes without known diabetes were invited to participate. Read More

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http://dx.doi.org/10.1159/000499468DOI Listing

Primary Large Cell Undifferentiated Carcinoma of the Ureter.

Med Princ Pract 2019 Mar 11. Epub 2019 Mar 11.

Objective: To report the first case in the literature of a primary large cell undifferentiated carcinoma (LCUC) of the ureter with a very aggressive behavior and dismal prognosis.

Clinical Presentation And Intervention: A 60 years-old woman with a history of intermittent macroscopic hematuria and mild to moderate right flank pain admitted to the Department of Urology. Tissue biopsies and cytological samples were taken. Read More

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http://dx.doi.org/10.1159/000499467DOI Listing
March 2019
1.113 Impact Factor

Altered Expression Levels of CD59, but not CD55, on Red Blood Cells in Stored Blood.

Med Princ Pract 2019 Mar 8. Epub 2019 Mar 8.

Objective: Red blood cells (RBCs) in storage undergo structural and biochemical changes that may cause functional effects. Studies exploring structural changes affecting the expression levels of CD55 and CD59 on RBCs are limited. The aim of the study was to investigate the pattern of expression of CD55 and CD59 on RBCs in stored blood from Arab donors. Read More

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http://dx.doi.org/10.1159/000499428DOI Listing

Determination of Salivary Myeloperoxidase, Immunoglobulin E and Tumor Necrosis Factor Alpha after Complete Denture Insertion.

Med Princ Pract 2019 Mar 8. Epub 2019 Mar 8.

Objective: To detect activities of salivary myeloperoxidase and concentrations of salivary tumor necrosis factor alpha (TNFα) as indicators of inflammatory reaction and salivary immunoglobulin E as an indicator of allergic reaction, after complete insertion of acrylic denture.

Subjects And Methods: Complete dentures were made for a uniform group of elderly patients, and saliva samples were taken immediately before they were given to the patients, as well as one, three, seven and thirty days after insertion of denture, with simultaneous monitoring of changes on the oral mucosa.

Results: After seven and thirty days of wearing upper and lower complete dentures, a non-significant increase in salivary myeloperoxidase and TNFα were proven as indicators of inflammation, No changes were observed in the values of salivary immunoglobulin E during a thirty-day observational period, which excluded the appearance of allergic reactions to acrylic materials in the tested group of patients. Read More

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http://dx.doi.org/10.1159/000499429DOI Listing
March 2019
8 Reads

Effectiveness of Multilevel Botulinum Toxin A Injection with Integrated Treatment Program on Spasticity Reduction in Non-ambulatory Young Children with Cerebral Palsy.

Med Princ Pract 2019 Mar 6. Epub 2019 Mar 6.

Objective: The aim of the present study was to evaluate the effectiveness of multilevel Botulinum Toxin A (BTX-A) injection, as part of an integrated approach, for the treatment of spasticity in non-ambulatory young children with diplegic Cerebral Palsy (CP).

Subjects And Methods: Seventeen non-ambulatory patients aged 4-8 years with diplegic CP (Gross Motor Function Classification System (GMFCS) level IV were evaluated before and at 1st, 3rd and 6th months after BTX-A injection. The effect of BTX-A on spasticity of gastrocnemius and hamstring muscles were assessed using the Modified Ashworth Scale (MAS) and Modified Tardieu Scale (MTS). Read More

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http://dx.doi.org/10.1159/000499369DOI Listing
March 2019
2 Reads

Differentiation of Cognitive Deficit Profiles in Multiple Sclerosis Patients: Latent Profile Analysis.

Med Princ Pract 2019 Mar 4. Epub 2019 Mar 4.

Objective: The purpose of this study was to ascertain whether the application of Audio Recorded Cognitive Screen (ARCS) in cognitive functions screening of persons with multiple sclerosis (MS) differentiates profiles of existing cognitive deficits and whether this instrument can discriminate accurately between subjects who are cognitively intact and those with a cognitive disorder.

Subjects And Methods: The research was conducted on a sample of 359 subjects, with two subsets of participants; 108 persons with a relapsing-remitting form of MS and 251 persons from the general population.

Results: We labeled the three profiles obtained by applying the ARCS questionnaire - the cognitively intact profile, the profile of cognitively intact with visuospatial difficulties, and the profile of persons with cognitive deficit. Read More

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http://dx.doi.org/10.1159/000499312DOI Listing
March 2019
2 Reads

Clinical Performance of Allplex Respiratory Panel 1 Test Compared to Simplexa Flu A/B and RSV for the Detection of Influenza Virus and Respiratory Syncytial Virus Infection Including Their Subtyping.

Med Princ Pract 2019 Mar 4. Epub 2019 Mar 4.

Objective: The Allplex Respiratory Panel 1 (ARP) is a new assay based on a real-time polymerase chain reaction (RT-PCR) for the detection of influenza A (Flu A), influenza B virus (Flu B) and respiratory syncytial virus (RSV), including subtyping by multiple detection temperature (MuDT) technology. We evaluated the performance of the Allplex Respiratory Panel compared to SimplexaTM Flu A/B & RSV assay (SP) and other diagnostic tools.

Materials And Methods: A total of 372 samples were collected from patients at the Korea University Guro Hospital in Seoul, Korea. Read More

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http://dx.doi.org/10.1159/000499313DOI Listing
March 2019
2 Reads

Micro-CT Calibration Using Polymers and Minerals for Enamel Mineral Content Quantitation.

Med Princ Pract 2019 Mar 1. Epub 2019 Mar 1.

Objective: To develop calibration standards (CSs) that are readily available for clinical researchers for the quantitation of enamel mineral content.

Method: Polyethylene-terephthalate (PET), acetal, polyphenylene-sulphide (PPS), selenite, Egyptian-alabaster, aragonite and fluorite were fashioned into discs, their densities were measured and stacked for micro-CT examination. Frame-averaging, flat-field correction, pre-filtration and beam-hardening correction were applied. Read More

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http://dx.doi.org/10.1159/000499186DOI Listing
March 2019
1 Read

Diversity of Nontuberculous Mycobacteria in Kuwait: Rapid Identification and Differentiation of Mycobacterium Species by Multiplex PCR, INNO-LiPA Mycobacteria v2 Assay and PCR Sequencing of rDNA.

Med Princ Pract 2019 Feb 14. Epub 2019 Feb 14.

Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.

Objective: Nontuberculous mycobacteria (NTM) often cause disease that is clinically indistinguishable from tuberculosis. Specific identification is important as treatment varies according to Mycobacterium species causing the infection. This study used multiplex PCR (mPCR) assay for rapid differentiation of mycobacterial growth indicator tube 960 system (MGIT) cultures as Mycobacterium tuberculosis (MTB) or NTM together with INNO LiPA Mycobacteria v2 assay (LiPA) and/or PCR sequencing of rDNA for species-specific identification of selected MTB and all NTM isolates in Kuwait. Read More

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http://dx.doi.org/10.1159/000498910DOI Listing
February 2019
2 Reads

Whipple's Disease: A Case Report.

Med Princ Pract 2019 Feb 14. Epub 2019 Feb 14.

Objective

Whipple's disease is a very rare systemic infectious disease, with an incidence of 1 in one million, which may be fatal if not diagnosed and treated appropriately.

Clinical Presentation and Intervention

Herein we will describe a 49 years old male patient admitted to the hospital with the signs of severe malabsorption and diagnosed with Whipple's disease.

Conclusion

We aimed to emphasize the Whipple's disease to be kept in mind for the prompt diagnosis and treatment of patients with malabsorption. Read More

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http://dx.doi.org/10.1159/000498909DOI Listing
February 2019
3 Reads

Thyroid Ultrasound Reports: Deficiencies and Recommendations.

Med Princ Pract 2019 Feb 10. Epub 2019 Feb 10.

Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.

Objective: Thyroid ultrasound plays a major role in the clinical management of patients with thyroid nodules. Comprehensive reporting enables malignant risk stratification and biopsy decisions. In this study, we aimed at a systematic evaluation of the content and completeness of thyroid radiology reports. Read More

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http://dx.doi.org/10.1159/000497789DOI Listing
February 2019
3 Reads

Association between peripheral artery disease and major adverse cardiovascular events in patients with acute coronary syndrome: findings from the Gulf COAST registry.

Med Princ Pract 2019 Feb 10. Epub 2019 Feb 10.

Objective: To evaluate the association between peripheral artery disease (PAD) and major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) in the Arabian Gulf.

Methods: Data was analyzed from 4044 consecutive patients diagnosed with ACS admitted to 29 hospitals in four Arabian Gulf countries from January 2012 to January 2013. PAD was defined as any of the following: claudication, amputation for arterial vascular insufficiency, vascular reconstruction, bypass surgery, or percutaneous intervention in the extremities, documented aortic aneurysm or ankle brachial index of < 0. Read More

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http://dx.doi.org/10.1159/000497790DOI Listing
February 2019
2 Reads

Age-Specific Reference Ranges of Prostate-Specific Antigen Among Saudi Men As a Representation of the Arab Population.

Med Princ Pract 2019 Feb 7. Epub 2019 Feb 7.

Objective: To describe the reference ranges of serum prostate-specific antigen (PSA) in Saudi men. Materials/Subjects and Methods: Saudi males, aged 30 and above, were invited to participate in the study. Blood samples were taken from each subject to determine serum levels of PSA. Read More

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http://dx.doi.org/10.1159/000497744DOI Listing
February 2019
2 Reads

Galectin-3 in Acute Myocardial Infarction Patients with Atrial Fibrillation.

Med Princ Pract 2019 Feb 6. Epub 2019 Feb 6.

Department of Pharmacology and Toxicology, Medical Faculty, Nis, Serbia.

Objective: Atrial fibrillation (AF) is common in acute myocardial infarction (AMI), and galectin-3 is possibly involved in its occurrence. Galectin-3 has been shown to play a central role in fibrosis and tissue remodeling and has a role in inflammatory and proliferative responses. The aim of our study was to measure galectin-3 levels in patients with myocardial infarction and to compare its levels in patients with or without AF, in order to investigate the potential predictive role of galectin-3 in this setting. Read More

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http://dx.doi.org/10.1159/000497611DOI Listing
February 2019
2 Reads

Comparison of Subjective and Objective Assessments of Neurosensory Function after Lingual Nerve Repair.

Med Princ Pract 2019 Feb 6. Epub 2019 Feb 6.

Objective: Mandibular third molar extractions are important in oral maxillofacial surgery. Damage to the lingual nerves, although rare, is a possible complication. There are reports of postoperative recovery after lingual nerve repair, but few reports compared subjective and objective assessments of neurosensory function. Read More

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https://www.karger.com/Article/FullText/497610
Publisher Site
http://dx.doi.org/10.1159/000497610DOI Listing
February 2019
3 Reads

Pigment Epithelium-Derived Factor Affects Angiogenesis in Celiac Disease.

Med Princ Pract 2019 02 6. Epub 2019 Feb 6.

Objective: Recent studies have demonstrated that angiogenesis is impaired in patients with celiac disease (CD). In this study, we evaluated the levels of the novel anti-angiogenic factor pigment epithelium-derived factor (PEDF) in CD patients.

Methods: 84 patients were included in the study; 71 patients with celiac disease and 13 healthy controls. Read More

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https://www.karger.com/Article/FullText/497612
Publisher Site
http://dx.doi.org/10.1159/000497612DOI Listing
February 2019
4 Reads

Glomerular filtration rate as a prognostic factor for long-term mortality after acute pulmonary embolism.

Med Princ Pract 2019 Feb 4. Epub 2019 Feb 4.

Objective:
To determine the impact of estimated glomerular filtration rate (eGFR) and creatinine clearance (CrCl) on long-term all-cause mortality following acute PE in association with other routine laboratory analyses and comorbidities.
Materials (Subjects) and Methods
The prospective study enrolled 141 consecutive patients presenting with objectively confirmed acute PE. Demographic, clinical data, comorbidities and laboratory values were recorded. Read More

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http://dx.doi.org/10.1159/000497436DOI Listing
February 2019
3 Reads

Orthodontically Relevant Manifestations in People with Rare Diseases.

Med Princ Pract 2019 Feb 4. Epub 2019 Feb 4.

Department of Oral Surgery and Dental Emergency Care, School of Dentistry, Faculty of Health, Witten/Herdecke University, Witten, Germany.

Background: Approximately 15% of all rare diseases occur with orofacial manifestations. Symptoms and manifestations of relevance to orthodontists represent a considerable proportion of these diseases and require appropriate strategies for their treatment. This article provides an overview of the orthodontically relevant manifestations of rare diseases. Read More

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http://dx.doi.org/10.1159/000497437DOI Listing
February 2019

Precision Diabetes Is Slowly Becoming a Reality.

Med Princ Pract 2019 27;28(1):1-9. Epub 2019 Jan 27.

Department of Molecular Genetics, Madras Diabetes Research Foundation, Chennai, India.

The concept of precision medicine is becoming increasingly popular. The use of big data, genomics and other "omics" like metabolomics, proteomics and transcriptomics could make the dream of personalised medicine become a reality in the near future. As far as polygenic forms of diabetes like type 2 and type 1 diabetes are concerned, interesting leads are emerging, but precision diabetes is still in its infancy. Read More

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http://dx.doi.org/10.1159/000497241DOI Listing
January 2019
1 Read

Maternal Hematological Parameters and Placental and Umbilical Cord Histopathology in Intrauterine Growth Restriction.

Med Princ Pract 2019 Jan 27. Epub 2019 Jan 27.

Department of Obstetrics and Gynecology, University of Szeged, Szeged, Hungary.

Objective: To investigate the placental and umbilical cord histopathology in intrauterine growth restriction (IUGR) and their relation to second-trimester maternal hematological parameters.

Materials And Methods: Patients were selected for the IUGR group based on estimated fetal weight below the 10th percentile. Patients were recruited into the control group randomly. Read More

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http://dx.doi.org/10.1159/000497240DOI Listing
January 2019
3 Reads