1,710 results match your criteria Mediastinal Germ Cell Tumor Imaging


Cervical ganglioneuroma: A case report and review of the literature.

Medicine (Baltimore) 2019 Apr;98(15):e15203

Department of Otolaryngology-Head and Neck Surgery, First Hospital of Jilin University, Jilin University, Changchun 130021, Jilin Province, China.

Rationale: Ganglioneuromas are benign neoplasm of neuroblastic origin which arise from central or peripheral parts of the autonomic nervous system. They are normally found at posterior mediastinum, retroperitoneum, and the adrenal gland but ganglioneuromas are rarely found in the cervical region.

Patient Concerns: A 12-year-old boy was admitted with a left-lateral neck mass slow growing over a 7-days duration. Read More

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http://dx.doi.org/10.1097/MD.0000000000015203DOI Listing
April 2019
2 Reads

Idiopathic gonadotropin-independent precocious puberty - is regular surveillance required?

J Pediatr Endocrinol Metab 2019 Apr;32(4):403-407

Consultant Paediatric Endocrinologist, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

Context Germ cell tumours (GCTs) secreting β-human chorionic gonadotropin (β-HCG) are a rare cause of gonadotropin-independent precocious puberty (GIPP). Case description A 5.7-year-old boy presented with GIPP. Read More

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http://dx.doi.org/10.1515/jpem-2018-0419DOI Listing
April 2019
1 Read

Clinical and radiographic characterization of primary seminomas and nonseminomatous germ cell tumors.

Niger J Clin Pract 2019 Mar;22(3):342-349

Department of Medical Oncology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, P. R. China.

Background: Primary malignant mediastinal germ cell tumors (PMMGCTs) including seminomas and nonseminomatous germ cell tumors (NSGCTs) are rare, and sometimes the diagnosis is very difficult.

Purpose: The purpose of this study is to compare the clinical characteristics, biomarkers, and imaging findings of seminomas and NSGCTs and to determine whether these features could help distinguish these two types of PMMGCT.

Material And Methods: A retrospective study of 24 male patients with histopathologically proven PMMGCT was performed. Read More

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http://dx.doi.org/10.4103/njcp.njcp_448_18DOI Listing
March 2019
4 Reads

A case report of a giant mature teratoma of the thyroid gland in a young girl.

Medicine (Baltimore) 2019 Mar;98(9):e14703

Rationale: Teratomas are extremely rare in the thyroid gland. A cervical teratoma presenting as a cystic or mixed thyroid lesion can be easily confused with a thyroglossal duct cyst. It is difficult for pediatricians to differentiate between these 2 types of lesions. Read More

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http://dx.doi.org/10.1097/MD.0000000000014703DOI Listing
March 2019
1 Read

[Pigmented Paraganglioma in the Anterior Mediastinum].

Kyobu Geka 2019 Feb;72(2):108-111

Department of Thoracic Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.

Pigmented paraganglioma of the anterior mediastinum is extremely rare. We report a 72-year-old female patient who was pointed out an anterior mediastinum tumor showed by chest computed tomography(CT) scan during a medical check up. The tumor was 50×35 mm showing gradual enlargement and was slightly homogenously contrasted by CT scan and magnetic resonance imaging(MRI). Read More

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February 2019
2 Reads

Parapharyngeal Ganglioneuroma Detected by 18F-FDG PET/CT in a Patient With Hodgkin Lymphoma.

Clin Nucl Med 2019 Mar;44(3):240-243

Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan.

A 38-year-old woman with anterior mediastinal Hodgkin lymphoma underwent F-FDG PET/CT, revealing abnormal uptake at the left retrostyloid parapharyngeal space. After chemotherapy, follow-up PET/CT showed regression of previously avid lesions but not the left retropharyngeal mass. Subsequent MRI revealed findings suggestive of neurogenic tumor. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002444DOI Listing
March 2019
6 Reads

Growing teratoma syndrome in primary mediastinal germ cell tumor: our experience.

Asian Cardiovasc Thorac Ann 2019 Feb 15;27(2):98-104. Epub 2019 Jan 15.

5 Department of Cardiovascular and Thoracic Surgery, Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry, India.

Background: Growing teratoma syndrome is a rare phenomenon seen in nonseminomatous germ cell tumors after chemotherapy, where the tumor grows paradoxically despite normalization of tumor markers. It has been found in various locations, most commonly, the retroperitoneum in association with metastatic disease. The occurrence of growing teratoma syndrome in a mediastinal primary is very rare and there are only a few reports in the literature. Read More

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http://dx.doi.org/10.1177/0218492318823345DOI Listing
February 2019
10 Reads

Case of Solitary Peritoneal Metastasis From Atypical Bronchopulmonary Carcinoid on 18F-FDG PET/CT.

Clin Nucl Med 2019 Mar;44(3):e154-e157

Department of Histopathology, HCG Cancer Centre, Bangalore, India.

Atypical lung carcinoids frequently metastasize to mediastinal nodes, liver, bone, lungs, and brain and rarely to ovaries, pancreas, subcutaneous, and skin. Solitary peritoneal metastasis is extremely rare and unreported previously. We present a case of a 36-year-old woman with cough, hemoptysis, dyspnea with detection of lung mass, and incidental detection of pelvic mass. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002441DOI Listing
March 2019
5 Reads

[Temporary Bypass with 5-Fr Catheter for Reconstruction of Superior Vena Cava].

Kyobu Geka 2018 12;71(13):1077-1080

Division of Thoracic Surgery, Kobe University, Kobe, Japan.

A 21-year-old man was referred to our hospital because of an abnormal shadow on a routine chest radiogram. Enhanced computed tomography showed an 83×74 mm mass in the anterior mediastinum, with invasion of the superior vena cava (SVC). Surgical resection with sternotomy was performed. Read More

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December 2018
16 Reads

Huge mediastinal germ cell tumor with "white-out" chest X-ray imaging of the left lung.

Thorac Cancer 2019 Feb 18;10(2):386-387. Epub 2018 Dec 18.

Department of General Thoracic Surgery, Sagamihara Kyodo Hospital, Sagamihara, Japan.

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http://dx.doi.org/10.1111/1759-7714.12941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360235PMC
February 2019

Surgical removal of adult recurrent neuroblastoma located in the posterior mediastinum and retroperitoneum: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13642

Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.

Rationale: Adult recurrent neuroblastoma is extremely rare, especially in the posterior mediastinum and retroperitoneal cavity. The surgical treatment of this special part of the tumor is also a clinical difficulty.

Patient Concerns: This study reports a case of a 24-year-old man with a history of treated posterior mediastinal neuroblastoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000013642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320002PMC
December 2018
2 Reads

Multiple intercostal neurilemmomas in a Chinese woman.

J Cancer Res Ther 2018 Dec;14(Supplement):S1220-S1222

Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing University Medical School, Nanjing, People's Republic of China.

Neurilemmomas are rare tumors of neural crest cell origin that occur most commonly in the head and neck region. Intercostal neurilemmomas are extremely rare and are mostly seen as solitary tumors in the posterior mediastinum. Only one case report of multiple intercostal neurilemmomas has been documented previously. Read More

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http://www.cancerjournal.net/text.asp?2018/14/7/1220/211661
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http://dx.doi.org/10.4103/jcrt.JCRT_540_16DOI Listing
December 2018
13 Reads

Can benign lymphoid tissue changes in F-FDG PET/CT predict response to immunotherapy in metastatic melanoma?

Cancer Immunol Immunother 2019 Feb 26;68(2):297-303. Epub 2018 Nov 26.

Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.

Background: An association between immune-related adverse events (irAEs) caused by immunotherapeutic agents and the clinical benefit of immunotherapy has been suggested. We retrospectively evaluated by means of F-FDG PET/CT lymphoid tissue changes in the mediastinal/hilar lymph nodes and the spleen in response to ipilimumab administration in metastatic melanoma.

Methods: A total of 41 patients with unresectable metastatic melanoma underwent F-FDG PET/CT before the start of ipilimumab (baseline PET/CT), after two cycles (interim PET/CT) and at the end of treatment (late PET/CT). Read More

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http://dx.doi.org/10.1007/s00262-018-2279-9DOI Listing
February 2019
1 Read

Metastatic thymic carcinoid responds to chemoradiation and octreotide: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13286

Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Rationale: Thymic carcinoids are a rare type of malignant neuroendocrine tumors which have a poor prognosis due to their distant metastasis, invasive behaviour, and postoperative recurrence. Surgical resection is still the fundamental mode for treating thymic carcinoids. Here, we report the rapid shrinkage of an atypical thymic carcinoid with multiple metastases following chemoradiation plus octreotide as a first-line therapy PATIENT CONCERNS:: A 39-year-old Chinese man presented with chest tightness, dyspnea with a history of lumbago and untreated malignant thymoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000013286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393003PMC
November 2018
19 Reads

Perioperative management of an anterior mediastinal teratoma in an infant: one more tool in the toolbox.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.

Anterior mediastinal masses present a significant challenge in the perioperative period. Standard anaesthetic induction and airway management are often not feasible due to the risk of complete respiratory and/or cardiovascular collapse. Invasive manoeuvres, such as extracorporeal membrane oxygenation, cardiac bypass, or tracheal or bronchial stenting, are sometimes not applicable due to significant anatomic aberration. Read More

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http://dx.doi.org/10.1136/bcr-2018-227022DOI Listing
November 2018
9 Reads

Medullary Thyroid Carcinoma: Do Ultrasonography and F-DOPA-PET-CT Influence the Initial Surgical Strategy?

Ann Surg Oncol 2018 Dec 10;25(13):3919-3927. Epub 2018 Oct 10.

Section "Endocrine Surgery", Division of General Surgery, Department of Surgery, Medical University Vienna, Vienna, Austria.

Background: At the time of diagnosis, one-third of medullary thyroid carcinoma (MTC) patients show lymph node (LN) or distant metastasis. A metastasized MTC requires different surgical strategies.

Objective: This study aimed to determine the value of ultrasound and [18F]fluoro-dihydroxyphenylalanine positron emission tomography with computed tomography (F-DOPA-PET-CT) in localizing MTC, as well as LN and distant metastasis. Read More

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http://link.springer.com/10.1245/s10434-018-6829-3
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http://dx.doi.org/10.1245/s10434-018-6829-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245031PMC
December 2018
7 Reads

Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry.

J Clin Oncol 2018 Oct 4:JCO1800210. Epub 2018 Oct 4.

Richard Cathomas, Kantonsspital Graubünden, Chur; Dirk Klingbiel, Swiss Group for Clinical Cancer Research Coordinating Center; Silke Gillessen, University of Bern; Jörg Beyer, Inselspital, Bern University Hospital, University of Bern, Bern; Christian Fankhauser, University of Zürich, Zürich; Silke Gillessen, Kantonsspital St Gallen, St Gallen, Switzerland; Brandon Bernard, Dana-Farber Cancer Institute, Boston, MA; Anja Lorch, University of Düsseldorf, Düsseldorf; Christoph Oing, University Medical Center Hamburg-Eppendorf, Hamburg; Marcus Hentrich, Rotkreuzklinikum München, München, Germany; Xavier Garcia del Muro, Institute Catalan of Oncology, Bellvitge Biomedical Research Institute, University of Barcelona, Barcelona, Spain; Franco Morelli, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo; Ugo De Giorgi, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto di Ricovero e Cura a Carattere Scientifico, Meldola, Italy; Mikhail Fedyanin, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia; and Hege Sagstuen Haugnes, University Hospital of North Norway and Universitetet i Tromsø-The Arctic University, Tromsø, Norway.

Purpose: Residual lesions after chemotherapy are frequent in metastatic seminoma. Watchful waiting is recommended for lesions < 3 cm as well as for fluorodeoxyglucose (FDG) positron emission tomography (PET)-negative lesions ≥ 3 cm. Information on the optimal management of PET-positive residual lesions ≥ 3 cm is lacking. Read More

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http://dx.doi.org/10.1200/JCO.18.00210DOI Listing
October 2018
13 Reads

Renin-producing germ cell tumor in the pineal apparatus and mediastinum: A rare case report.

J Cancer Res Ther 2018 Sep;14(Supplement):S806-S808

Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.

Ectopic extrarenal renin-producing tumor is a rare disease with approximately 30 case reports in English literature. We herein present the first case of renin-producing germ cell tumors in the pineal apparatus and mediastinum. A 26-year-old man who had undergone craniotomy for the treatment of pineal tumor was found to have hypertension at a regular visit postoperatively. Read More

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http://dx.doi.org/10.4103/0973-1482.180682DOI Listing
September 2018
3 Reads

Challenges in the surgical treatment of undiagnosed functional paragangliomas: A case report.

Medicine (Baltimore) 2018 Sep;97(38):e12478

Introduction: Paragangliomas (PGs) or extra-adrenal pheochromocytomas are rare neuroendocrine neoplasms of ubiquitous distribution. Those that produce excess catecholamine are categorized as functional, and those that do not are categorized as nonfunctional. Although modern medical technology is becoming more widespread, there are still substantial risks of misdiagnosis or missed diagnosis of PGs. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809210-0009
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http://dx.doi.org/10.1097/MD.0000000000012478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160181PMC
September 2018
8 Reads

Positron emission tomography/computed tomography as a clinical diagnostic tool for anterior mediastinal tumors.

Surg Today 2019 Feb 10;49(2):143-149. Epub 2018 Sep 10.

Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.

Purpose: The purpose of this study was to assess the usefulness of positron emission tomography/computed tomography (PET/CT) in the differential diagnosis of anterior mediastinal tumors.

Methods: A total of 94 patients with anterior mediastinal masses or nodules (male, n = 41; female, n = 53; age, 17-84 years) were retrospectively evaluated. All patients were evaluated by PET/CT and the masses or nodules were histologically diagnosed in our institution. Read More

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http://dx.doi.org/10.1007/s00595-018-1712-1DOI Listing
February 2019
7 Reads

[Chest CT Findings of Primary Neuroendocrine Tumor of Thymus:Analysis of 7 Cases].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Aug;40(4):468-472

Department of Radiology,Chinese PLA General Hospital,Beijing 100853,China.

Objective To explore the clinical features of primary neuroendocrine tumor of thymus (pNET) on computed tomography (CT). Method CT findings and clinical features of 7 patients with pathologically confirmed primary pNET were retrospectively analyzed. Results There were 2 male and 5 female patients aged (52. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.10365DOI Listing
August 2018
13 Reads

Mediastinal metastasectomy from a primary germ cell testicular tumour resulting in occult thoracic duct injury and chylothorax.

BMJ Case Rep 2018 Aug 17;2018. Epub 2018 Aug 17.

Cardiothoracic Surgery, Fiona Stanley Hospital, Perth, Western Australia, Australia.

A 22-year-old man underwent mediastinal metastasectomy for a testicular germ cell tumour via median sternotomy. Intraoperatively, the tumour was massive, measuring 88 mm in anterior-posterior (AP) diameter. It was densely adherent to the trachea and aggressive debulking resulted in tracheal injury. Read More

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http://dx.doi.org/10.1136/bcr-2018-225715DOI Listing
August 2018
14 Reads

Postpartum Diagnosis of Cardiac Paraganglioma: A Case Report.

J Emerg Med 2018 10 20;55(4):e101-e105. Epub 2018 Jul 20.

Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.

Background: Extra-adrenal pheochromocytomas, or paragangliomas, originate from neural crest chromaffin cells and can be found anywhere along the sympathetic chain from head to toe.

Case Report: A 34-year-old female presented 4 days postpartum with episodes of palpitations, hypertension, and shortness of breath. Two episodes in the emergency department confirmed hypertension and supraventricular tachycardia (SVT). Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.05.034DOI Listing
October 2018
6 Reads

[Beta-hCG-producing thymic teratoma: an uncommon cause of peripheral precocious puberty].

Rev Chil Pediatr 2018 Jun;89(3):373-379

Servicio de Pediatría, Hospital Dr. Hernán Henríquez Aravena, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.

Introduction: Among the causes of peripheral precocious puberty in men are the beta-human cho rionic gonadotropin (Β-HCG)-secreting tumors, such as hepatoblastomas, dysgerminomas, chorio carcinomas, and immature teratomas. In pediatrics, the mediastinal teratomas are rare, representing the 7-10% of extragonadal teratomas.

Objective: To describe the case of a patient with peripheral precocious puberty due to a Β-HCG -secreting thymic teratoma. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000304DOI Listing
June 2018
16 Reads

Pediatric paraganglioma of the posterior mediastinum: A case report and review of literature.

Medicine (Baltimore) 2018 Jul;97(27):e11212

Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.

Rationale: Paraganglioma is rare in children and most pheochromocytomas originate in the adrenal gland.

Patient Concerns: The clinical characteristics, diagnosis, and managements in a 9-year-old boy who presented with vomiting and occasional headache with a blood pressure of 210/170 mm Hg was retrospectively reviewed. CT scan of the chest revealed a 7 × 5-cm-sized soft tissue mass in the left paraspinal area. Read More

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http://dx.doi.org/10.1097/MD.0000000000011212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076022PMC
July 2018
3 Reads

Peritoneal Myeloid Sarcoma in a Patient Treated for a Testicular Seminoma.

Am J Case Rep 2018 Jun 29;19:763-766. Epub 2018 Jun 29.

Division of Medical Oncology, Mercy Hospital, Metz-Thionville Regional Hospital Center, Ars-Laquenexy, France.

BACKGROUND Myeloid sarcoma is a rare extramedullary soft tissue neoplasm composed of myeloblastic cells, usually associated to hematologic tumor disorders and a poor prognosis. Its diagnosis is very difficult as radiological images are not specific. Histology and immunohistochemistry are necessary for an accurate diagnosis. Read More

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https://www.amjcaserep.com/abstract/index/idArt/910434
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http://dx.doi.org/10.12659/AJCR.910434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055577PMC
June 2018
16 Reads

Giant small-cell neuroendocrine carcinoma infiltrating the heart.

Kardiol Pol 2018 ;76(6):1023

1st Department of Cardiology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland; Department of General & Experimental Pathology with Centre for Preclinical Research and Technology (CEPT), Medical University of Warsaw, Pawińskiego 4, 02-097 Warszawa, Poland.

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http://dx.doi.org/10.5603/KP.2018.0123DOI Listing
November 2018
1 Read

Intradural Ganglioneuroma Mimicking Lumbar Disc Herniation: Case Report.

World Neurosurg 2018 Sep 7;117:40-45. Epub 2018 Jun 7.

Department of Neurosurgery, Rio Hortega University Hospital, Valladolid, Castilla y León, Spain.

Background: Ganglioneuroma (GN) is a slow-growing tumor originating from the neural crest-derived cells, which form the sympathetic nervous system. These tumors can affect anywhere along the peripheral autonomic ganglion sites and are most commonly found in the mediastinum and retroperitoneum. Spinal GNs are extremely rare and, so far, only 1 case arising from a lumbar nerve root has been reported in the English literature. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.225DOI Listing
September 2018
5 Reads

[Atypical Pulmonary Carcinoid Tumor with Elevated Serum ProGRP;Report of a Case].

Kyobu Geka 2018 Mar;71(3):236-239

Department of Thoracic Surgery, Mie Chuo Medical Center, Tsu, Japan.

We report a case of an atypical pulmonary carcinoid with high serum ProGRP. A 78-year-old man was found to have an abnormal shadow by a chest X-ray. Chest computed tomography (CT) revealed a solitary pulmonary nodule in the right middle lobe, which was homogeneous, well demarcated, and round. Read More

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March 2018
2 Reads

Intrapericardial gossypiboma: Rare cause of intrathoracic mass.

Int J Surg Case Rep 2018 3;47:75-79. Epub 2018 May 3.

Department of Paediatric Surgery, All India Institute of Medical Sciences, Patna, India. Electronic address:

Introduction: Gossypiboma is a retained surgical sponge inside our body after surgical intervention. It is most commonly found in abdominal cavity. Its occurrence in thoracic cavity as intrapericardial gossypiboma is extremely rare. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.04.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994740PMC
May 2018
6 Reads

Immature teratoma mimicking pulmonary stenosis: a case report.

J Med Case Rep 2018 May 9;12(1):125. Epub 2018 May 9.

Medical Faculty, University of Prishtina, Prishtina, Republic of Kosovo.

Background: Immature teratoma in a mediastinal location is a rare disease that might present as a valve pathology. Germ cell tumors with mediastinal locations account for up to 6% of immature teratoma cases. We present a case of an immature teratoma located primarily in the anterior mediastinum that manifested solely through symptoms of pulmonary stenosis. Read More

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http://dx.doi.org/10.1186/s13256-018-1651-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941325PMC
May 2018
12 Reads

Heart glows when a Cook needle enters the pericardium.

Asian Cardiovasc Thorac Ann 2018 Jun 7;26(5):419. Epub 2018 May 7.

All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

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http://dx.doi.org/10.1177/0218492318776869DOI Listing

Extensive spinal extradural ganglioneuroma of the lumbar spine: mimicking lymphoma.

Eur Spine J 2018 07 29;27(Suppl 3):520-525. Epub 2018 Mar 29.

Department of Pathology, CHA Bundang Medical Center, CHA University, School of Medicine, 59, Yatap-ro, Bundang-gu, Seongnam-si, 13496, Gyeonggi-do, Republic of Korea.

Background: Ganglioneuromas are rare, benign, well-differentiated tumors arising from neural crest cells that commonly occur in the posterior mediastinum, retroperitoneum, cervical spine, and adrenal gland. We report an unusual case of an extensive spinal extradural ganglioneuroma, circumferentially and longitudinally affecting the extradural space of the lumbar spine and continuously invading bilateral psoas muscles.

Case Description: A 32-year-old man presented with a 1-week history of abdominal pain and diarrhea. Read More

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http://dx.doi.org/10.1007/s00586-018-5568-2DOI Listing
July 2018
7 Reads

Primary cervical ganglioneuroblastoma: A case report.

Medicine (Baltimore) 2018 Mar;97(12):e0090

Department of Otorhinolaryngology, Head & Neck Surgery, West China Hospital.

Rationale: Ganglioneuroblastoma is usually located in the adrenal gland, retroperitoneal ganglia, or posterior mediastinum, but rarely occurs in the parapharyngeal space.

Patient Concerns: A 4-year-old girl presented with complaint of progressive inspiratory dyspnea and dysphagia, accompanying left-side Horner's syndrome.

Diagnose: Computed tomography (CT) scan revealed a giant mass with irregular low density in left oropharyngeal and posterior pharyngeal wall. Read More

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http://dx.doi.org/10.1097/MD.0000000000010090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895351PMC
March 2018
8 Reads

Cough, Hemoptysis and Hair Expectoration: An Intrapulmonary Teratoma.

J Coll Physicians Surg Pak 2018 03;28(3):243-244

Department of Pathology & Laboratory Medicine, The Aga Khan University and Hospital, Karachi.

Teratomas can be found in different organs of the body and may involve gonads, saccrococcygeal region, mediastinum and other sites. Intrathoracic teratomas always occur in mediastinum and less often arise within the lung. As teratomas mostly involve sex organs (gonads), they rarely occur as extra-gonadal tumors accounting for only 3% of all the cases and very small percentage of such tumors occur in mediastinum. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.03.243DOI Listing
March 2018
9 Reads

Large Cell Carcinoma with Adenocarcinoma in Lung.

J Coll Physicians Surg Pak 2018 03;28(3):240-242

Department of Thoracic Pathology, Gaziosmanpasa University, 60250 Tokat, Turkey.

Large cell neuroendocrine carcinoma (LCNC) is a rare and aggressive cancer accounting for 3% of all lung cancers. A small percentage of LCNC called combined LCNC, can be seen in combinations with other lung tumor types. Multimodal therapy is proposed for this type of tumor but there is no any significant therapy since it is very rare tumor. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.03.240DOI Listing
March 2018
1 Read

Anterior mediastinal mass.

J Bras Pneumol 2018 Jan-Feb;44(1)

. Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil.

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http://dx.doi.org/10.1590/S1806-37562017000000381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104533PMC
January 2019
11 Reads

Middle mediastinal schwannoma concealed by asthma and GORD.

BMJ Case Rep 2018 Mar 13;2018. Epub 2018 Mar 13.

Department of Surgery, University of Santo Tomas Hospital, Manila, Philippines.

Neurogenic tumours of the mediastinum in adults occur most often at the posterior mediastinum, majority of which are benign of nerve sheath in origin. A 72-year-old woman, known asthmatic, presented with chronic symptoms of hoarseness, dysphagia, chest heaviness, easy fatigability, cough, epigastric pain, feeling of abdominal fullness and choking with food intake and at a supine position. Treated for other disorders, routine chest X-ray incidentally found a homogenous convex radiodensity at the right paratracheal area; mass which was also observed with CT and 18F-fludeoxyglucose-positron emission tomography/CT scan studies. Read More

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http://dx.doi.org/10.1136/bcr-2017-223795DOI Listing
March 2018
6 Reads

Endobronchial Tuberculosis Simulating Carcinoid Tumor.

J Coll Physicians Surg Pak 2018 Mar;28(3):S39-S41

Medical Student, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

Diagnosing endobronchial tuberculosis (EBTB) can be difficult due to the lack of specific signs and symptoms that differentiate it from other respiratory diseases, such as lung tumors. We hereby report a case of a very rare presentation of tuberculosis (TB) in a patient who presented with a dry cough and significant weight loss for 3 months. Chest X-ray and CT scan of the chest showed partial atelectasis and a segmental collapse of the right upper lobe and tumor-like arising from its bronchus along with a large right para-tracheal mediastinal lymphadenopathy, mimicking a metastatic (N2) disease. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.03.S39DOI Listing
March 2018
10 Reads
0.320 Impact Factor

[Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis].

Korean J Gastroenterol 2018 02;71(2):98-102

Department of Radiology, Kangwon National University School of Medicine, Chuncheon, Korea.

We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Read More

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http://dx.doi.org/10.4166/kjg.2018.71.2.98DOI Listing
February 2018
7 Reads

Lobulated esophageal schwannoma resected with concurrent approach from the thorax and cervix.

World J Surg Oncol 2018 Feb 13;16(1):29. Epub 2018 Feb 13.

Department of Surgery, Gifu Prefectural General Medical Center, 4-6-1 Noisshiki, Gifu, Japan.

Background: Esophageal schwannomas are rare esophageal submucosal tumors. We herein report a case of a lobulated esophageal schwannoma resected with concurrent approach from the thorax and cervix.

Case Presentation: A 74-year-old woman visited our hospital with complaint of loss of consciousness, and a lobulated mediastinal tumor was discovered by chance in computed tomography. Read More

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http://dx.doi.org/10.1186/s12957-018-1334-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812219PMC
February 2018
3 Reads

Hepatic angiosarcomatous transformation of a mediastinal germinal cell tumor: A care case report.

Medicine (Baltimore) 2017 Dec;96(51):e9152

Department of Radiology, Memorial Sloan Kettering Cancer Center, York Avenue, New York, NY, USA.

Rationale: Mediastinal nonseminomatous germ cell tumor (NSGCT) is an uncommon entity. Metastatic hepatic sarcomatous transformation is rare.

Patient Concerns: We report a 24-year-old man with no previous related medical history presented with chest pain and left arm numbness. Read More

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http://dx.doi.org/10.1097/MD.0000000000009152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758148PMC
December 2017
6 Reads

Superior mediastinal typical carcinoid detected by 99mTc-MIBI SPECT/CT imaging: A case report.

Medicine (Baltimore) 2017 Dec;96(52):e9457

Rationale: This is a rare case of mediastinal typical carcinoid tumor with elevated parathyroid hormone (PTH) and hypercalcemia detected by Tc -methoxy-isobutyl-isonitrile(Tc-MIBI) single photon emission computed tomography/computed tomography (SPECT/CT) imaging.

Patient Concerns: A 65-year-old male patient presented with hypercalcemia and elevated PTH.

Diagnoses: The preoperative diagnosis was ectopic parathyroid adenoma in the right superior mediastinum. Read More

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http://dx.doi.org/10.1097/MD.0000000000009457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392737PMC
December 2017
7 Reads

Radiological features and metastatic patterns of thymic neuroendocrine tumours.

Clin Radiol 2018 05 6;73(5):479-484. Epub 2018 Jan 6.

Department of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address:

Aim: To investigate the clinical and image features of thymic neuroendocrine tumours (NETs), and characterise the radiological patterns of recurrence and metastasis on serial imaging studies.

Materials And Methods: The study included 14 patients (11 males) with a histopathological diagnosis of thymic NETs (one typical carcinoid, eight atypical carcinoid, and five large cell neuroendocrine carcinoma). Preoperative images were assessed for features of primary tumours. Read More

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http://dx.doi.org/10.1016/j.crad.2017.11.025DOI Listing
May 2018
8 Reads

Pathological diagnosis of pulmonary large cell neuroendocrine carcinoma by endobronchial ultrasound-guided transbronchial needle aspiration.

Thorac Cancer 2018 02 22;9(2):273-277. Epub 2017 Dec 22.

Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

Background: Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a relatively rare subtype of lung malignancy. According to revised 2015 World Health Organization (WHO) criteria for the pathological diagnosis of LCNEC, neuroendocrine markers must be examined by immunohistochemistry. In this study, we reevaluated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) samples of patients previously diagnosed with LCNEC using the revised WHO criteria. Read More

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http://dx.doi.org/10.1111/1759-7714.12576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792718PMC
February 2018
4 Reads

A 49-Year-Old Woman With Right Apical Thoracic Mass.

Chest 2017 12;152(6):e133-e138

Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Geisel School of Medicine at Dartmouth College, Hanover, NH.

A 49-year-old woman with a medical history of essential hypertension presented to the ED with severe pain in the left superior chest and dull aching pain in the upper flank, lasting for the last 2 days. Read More

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http://dx.doi.org/10.1016/j.chest.2017.08.012DOI Listing
December 2017
4 Reads

Imaging of Intrathoracic Paragangliomas.

Semin Ultrasound CT MR 2017 Dec 4;38(6):584-593. Epub 2017 Aug 4.

Department of Diagnostic Radiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX.

Intrathoracic paragangliomas are uncommon and only represent 1%-2% of paragangliomas. They are most commonly found in mediastinal compartments (aortopulmonary window or posterior mediastinum). Computed tomography, magnetic resonance, and specific nuclear medicine radiotracers are routinely used to characterize these lesions and help exclude other more common conditions. Read More

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http://dx.doi.org/10.1053/j.sult.2017.07.004DOI Listing
December 2017
5 Reads

Ganglioneuroma of the Neck: A case report.

Ethiop Med J 2017 Jan;55(1):69-71

Ganglioneuroma (GN) is benign tumor arising from sympathetic ganglion which commonly occurs at posterior mediastinum, retroperitoneum and adrenal gland. Rarely, it may also present in cervical region as slow growing painless neck mass. Here we present a 7 years old female child with 4 years duration of slow growing left lateral neck mass. Read More

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January 2017
3 Reads

CT fluoroscopy-guided core needle biopsy of anterior mediastinal masses.

Diagn Interv Imaging 2018 Feb 14;99(2):91-97. Epub 2017 Nov 14.

Department of Radiology, Okayama University Medical School, 2-5-1 Shikata-cho kita-ku, 700-8558 Okayama, Japan. Electronic address:

Objective: To retrospectively evaluate the safety, diagnostic yield, and risk factors of diagnostic failure of computed tomography (CT) fluoroscopy-guided biopsies of anterior mediastinal masses.

Materials And Methods: Biopsy procedures and results of anterior mediastinal masses in 71 patients (32 women/39 men; mean [±standard deviation] age, 53.8±20. Read More

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http://dx.doi.org/10.1016/j.diii.2017.10.007DOI Listing
February 2018
8 Reads

Radiological-pathological correlation of malignant teratoma with liposarcomatous transformation: Proven by repeated transthoracic needle biopsy.

Thorac Cancer 2018 01 6;9(1):185-188. Epub 2017 Nov 6.

Department of Pathology, Chonnam National University Medical School, Gwangju, South Korea.

A mediastinal germ cell tumor with a sarcomatous component is extremely rare and is accompanied by a poor prognosis. Clinical and radiologic diagnosis is very difficult. Herein, we report a rare case of anterior mediastinal malignant teratoma containing a growing liposarcomatous component and detail the diagnostic process. Read More

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http://dx.doi.org/10.1111/1759-7714.12553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754310PMC
January 2018
15 Reads