Search Our Scientific Publications & Authors

Osteoarthritis Cartilage 2019 Feb 23. Epub 2019 Feb 23.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; Program of Advanced Musculoskeletal Imaging (PAMI), Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Purpose: (1) To identify bone-shape changes from baseline to 3-years after anterior cruciate ligament reconstruction (ACLR). (2) to assess association between changes in bone-shape from baseline to 6-months and changes in cartilage matrix and patient functions and symptoms from baseline to 3-years after ACLR.

Methods: Bilateral knees of 30 patients with unilateral ACL injuries were scanned at baseline, 6-months, 1-, 2-, and 3-years after ACLR. Read More

Orthop J Sports Med 2019 Feb 6;7(2):2325967118824611. Epub 2019 Feb 6.

Department of Orthopedics and Sports Orthopedics, Rechts der Isar Hospital, Technical University of Munich, Munich, Germany.

Background: Degenerative medial meniscal tears and subsequent partial meniscal resection compromise meniscal function and lead to an overload of the medial compartment. In addition, lower limb alignment plays a key role in load distribution between the medial and lateral knee compartments, and varus alignment is a potential risk factor for medial osteoarthritis.

Purpose/hypothesis: The purpose of this biomechanical study was to investigate the effect of valgus and varus alignment on peak pressure and contact area in knees with concomitant horizontal medial meniscal tears and subsequent leaflet resection. Read More

J Arthroplasty 2019 Jan 17. Epub 2019 Jan 17.

Department of Orthopedic Surgery, Veterans Health Service Medical Center, Seoul, South Korea.

Background: This study compared the rates of plain radiographs and computed tomography (CT) for detecting lateral hinge fractures and to evaluate factors affecting lateral hinge fractures in patients following medial opening-wedge high tibial osteotomy (MOWHTO).

Methods: This prospective study included 59 patients (65 knees) undergoing MOWHTO for primary medial compartment osteoarthritis with a 2-year follow-up between 2013 and 2016. Clinical and radiographic evaluations were performed using Knee Society Score and Western Ontario and McMaster Universities Arthritis Index, and we calculated the hip-knee-ankle angle, weight-bearing line ratio, lateral distal femoral angle, medial proximal tibial angle, posterior tibial slope, osteotomy gap height, and osteotomy gap filling rate. Read More

Am J Sports Med 2019 Mar 23;47(3):606-611. Epub 2019 Jan 23.

Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Republic of Korea.

Background:: Arthroscopic meniscectomy has been commonly performed for persistent pain caused by degenerative medial meniscal posterior root tears (MMPRTs). However, risk factors that affect long-term outcomes and joint survivorship after meniscectomy are unclear.

Purpose:: To identify the risk factors associated with end-stage osteoarthritis after arthroscopic meniscectomy for degenerative MMPRT for middle-aged or elderly patients and to determine the joint survivorship according to the identified risk factors. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Jan;33(1):13-17

Department of Orthopaedics, the First Affiliated Hospital of Fujian Medical University, Fuzhou Fujian, 350005, P.R.China.

Objective: To analyse the effectiveness of unicompartmental knee arthroplasty (UKA) for the patients with spontaneous osteonecrosis of the knee (SONK).

Methods: Between January 2012 and December 2016, 31 patients with SONK was admitted and treated with medial UKA. All patients were examined by both plain radiography and magnetic resonance images. Read More

Bone Joint J 2019 01;101-B(1):24-33

University College London Hospitals; The Princess Grace Hospital; The NIHR Biomedical Research Centre at UCLH, London, UK.

Aims: The objectives of this study were to compare postoperative pain, analgesia requirements, inpatient functional rehabilitation, time to hospital discharge, and complications in patients undergoing conventional jig-based unicompartmental knee arthroplasty (UKA) versus robotic-arm assisted UKA.

Patients And Methods: This prospective cohort study included 146 patients with symptomatic medial compartment knee osteoarthritis undergoing primary UKA performed by a single surgeon. This included 73 consecutive patients undergoing conventional jig-based mobile bearing UKA, followed by 73 consecutive patients receiving robotic-arm assisted fixed bearing UKA. Read More

Surg Technol Int 2018 Dec 20;34. Epub 2018 Dec 20.

Joint Implant Surgeons, Inc., New Albany, Ohio, White Fence Surgical Suites, LLC New Albany, Ohio, Mount Carmel Health System, Columbus, Ohio.

Background: Treatment of isolated lateral compartment arthritic disease with partial knee arthroplasty remains underutilized in comparison to medial unicompartmental arthroplasty. This study examines the survival and outcome of lateral unicompartmental arthroplasty utilizing the first implant specifically developed for the lateral compartment.

Materials And Methods: A retrospective review was performed to detect lateral unicompartmental arthroplasty procedures performed in our practice between January 2013 and May 2016. Read More

J Magn Reson Imaging 2018 Dec 19. Epub 2018 Dec 19.

Muscle Imaging and Modeling Lab, Department of Radiology, UC San Diego, San Diego, California, USA.

Background: Diffusion tensor imaging (DTI) assesses underlying tissue microstructure, and has been applied to studying skeletal muscle. Unloading of the lower leg causes decreases in muscle force, mass, and muscle protein synthesis as well as changes in muscle architecture.

Purpose: To monitor the change in DTI indices in the medial gastrocnemius (MG) after 4-week unilateral limb suspension (ULLS) and to explore the feasibility of extracting tissue microstructural parameters based on a two-compartment diffusion model. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Dec 17. Epub 2018 Dec 17.

Department of Orthopaedics, University of North Carolina at Chapel Hill, 102 Mason Farm Rd # 2, Chapel Hill, NC, 27599, USA.

Purpose: Quadriceps weakness following anterior cruciate ligament reconstruction (ACLR) is linked to decreased patient-reported function, altered lower extremity biomechanics and tibiofemoral joint space narrowing. It remains unknown if quadriceps weakness is associated with early deleterious changes to femoral cartilage composition that are suggestive of posttraumatic osteoarthritis development. The purpose of the cross-sectional study was to determine if quadriceps strength was associated with T1ρ relaxation times, a marker of proteoglycan density, of the articular cartilage in the medial and lateral femoral condyles 6 months following ACLR. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Dec 12. Epub 2018 Dec 12.

Musculoskeletal and Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.

Purpose: To investigate, whether cartilage repair surgery for focal osteochondral defects at the knee results in less degenerative changes over 6 years in a MR imaging follow-up than morphologically initially identical defects in non-operated control subjects from the osteoarthritis initiative (OAI).

Methods: A total of 32 individuals received baseline and follow-up MRI. In n = 16 patients with cartilage repair [osteochondral autograft transfer system (OATS), n = 12; spongiosa-augmented matrix-associated autologous chondrocyte implantation (MACI), n = 4] MRI was performed preoperatively and after 5. Read More

J Orthop Res 2019 Feb 3;37(2):378-385. Epub 2019 Jan 3.

Department of Orthopaedics, The Ohio State University Wexner Medical Center, 2835 Fred Taylor Dr, Columbus, Ohio, 43202.

We sought to determine the relationship between (i) full-thickness cartilage defects and tibiofemoral subchondral surface ratio (SSR) and (ii) disability and quality of life in patients with mild radiographic osteoarthritis (OA) (Kellgren-Lawrence grade 2) or without radiographic OA (Kellgren-Lawrence grades 0 or 1)? A total of 642 participants from the Osteoarthritis Initiative (OAI) with baseline knee MRIs and a Kellgren-Lawrence grade 2 or less on both bilateral screening radiographs were included. The independent relationship was assessed between (i) full-thickness cartilage defect presence and tibiofemoral SSR and (ii) Knee Injury and Osteoarthritis Outcome Score (KOOS) quality of life (QOL), KOOS function in sports and recreation (KOOS-sport/rec), and Western Ontario and McMaster Universities Arthritis Index (WOMAC) disability score after adjustment for relevant confounders with multivariate regression modeling. The prevalence of medial full-thickness defects was 10. Read More

Sci Rep 2018 Nov 26;8(1):17351. Epub 2018 Nov 26.

Department of Applied Physics, University of Eastern Finland, POB 1627, FI-70211, Kuopio, Finland.

Use of knee joint finite element models for diagnostic purposes is challenging due to their complexity. Therefore, simpler models are needed for studies where a high number of patients need to be analyzed, without compromising the results of the model. In this study, more complex, kinetic (forces and moments) and simpler, kinetic-kinematic (forces and angles) driven finite element models were compared during the stance phase of gait. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Nov 21. Epub 2018 Nov 21.

Center for Orthopaedics and Trauma Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, 69118, Heidelberg, Germany.

Purpose: Whether unicompartimental or total knee arthroplasty is superior for treatment of anteromedial knee osteoarthritis, is still uncertain. Therefore, the purpose of this study was to evaluate clinical and radiological outcome as well as long-term survivorship of medial Oxford unicompartmental knee arthroplasty (OUKA) at an independent center with a minimum follow-up of 10 years.

Methods: This single-center retrospective cohort study reports the 10-15 years follow-up results of 113 consecutive patients (126 knees) after medial OUKA. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Nov 16. Epub 2018 Nov 16.

School of Health and Rehabilitation Sciences, The Ohio State University, 453 W 10th Avenue, Columbus, OH, USA.

Purpose: The purpose was to test the following hypotheses: (1) magnetic resonance imaging (MRI) markers of early knee cartilage degeneration would be present in the involved limb of young athletes after anterior cruciate ligament reconstruction (ACLR) and (2) poor knee function would be associated with MRI markers of cartilage degeneration.

Methods: Twenty-five young athletes after primary, unilateral ACLR (mean age, 16.7 years) were followed to 5-year post-return-to-sport (RTS) clearance, as a part of a larger, prospective cohort study in young athletes post-ACLR. Read More

Knee 2018 Dec 13;25(6):977-987. Epub 2018 Nov 13.

Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. Electronic address:

Background: Medial opening-wedge high tibial osteotomy (HTO) has been used to treat osteoarthritis of the medial compartment of the knee. However, this makes the proximal tibia a highly unstable structure and causes the plate to be a potential source of mechanical failure. Consequently, proper design and material use of the fixation device are essential in HTO, especially for overweight or full-weight-bearing patients. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Nov;32(11):1406-1410

Nanjing University of Chinese Medicine, Nanjing Jiangsu, 210023,

Objective: To investigate the effectiveness of double-plane high tibial osteotomy in treatment of medial compartment osteoarthritis.

Methods: The clinical data of 65 patients with medial compartment osteoarthritis who were treated with double-plane high tibial osteotomy between January 2014 and January 2017 was retrospectively analyzed. There were 28 males and 37 females. Read More

Knee 2018 Dec 7;25(6):1247-1253. Epub 2018 Nov 7.

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Background: Acquisition of appropriate anteroposterior (AP) stability depends on the prosthetic design and intraoperative soft tissue handling. A bi-cruciate stabilized (BCS) total knee arthroplasty (TKA) has a two cam-post mechanism, which substitutes for the anterior cruciate ligament and posterior cruciate ligament (PCL). Therefore, appropriate AP stability is expected. Read More

J Geriatr Phys Ther 2018 Nov 6. Epub 2018 Nov 6.

Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Karnataka, India.

Background And Purpose: Osteoarthritis (OA) of the knee joint results in chronic pain and functional decline among older adults. Hip muscle weakness has been observed in persons with knee OA and is claimed to increase the medial compartment loading on the knee joint. Although individual studies are available, no review has yet integrated the literature on the benefits of hip muscle strengthening for persons with knee OA. Read More

Can Assoc Radiol J 2018 Nov;69(4):450-457

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Orthopedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

Purpose: To evaluate whether mediopatellar plica and knee morphometric measurements obtained from magnetic resonance imaging (MRI) studies are associated with isolated medial patellofemoral osteoarthritis in young adults.

Methods: MRI studies from 60 patients with isolated medial patellofemoral osteoarthritis and 90 control patients with normal knee MRI studies were reviewed. The presence of mediopatellar plica, the presence of edema in the superolateral aspect of Hoffa's fat pad and suprapatellar fat pad, quadriceps and patellar tendinosis, and axial and sagittal alignment of the patellar and trochlear morphology were assessed using MRI. Read More

Skeletal Radiol 2018 Oct 24. Epub 2018 Oct 24.

Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.

Objective: To investigate whether subjects with diabetes show accelerated knee joint structural degeneration over 4 years compared to diabetes-free controls.

Materials And Methods: Two hundred forty-four participants with diabetes were selected from the Osteoarthritis Initiative cohort and matched with 244 diabetes-free controls. 3. Read More

Arthritis Care Res (Hoboken) 2019 Feb;71(2):218-226

Paracelsus Medical University Salzburg and Nuremberg, Salzburg, Austria, and La Trobe University, Bundoora, Australia.

Objective: To examine the impact of physical activity on cartilage thickness loss in knee osteoarthritis (OA).

Methods: A total of 689 participants with radiographic knee OA at baseline (Kellgren/Lawrence grade ≥2) from the Osteoarthritis Initiative completed the Physical Activity Scale for the Elderly (PASE) questionnaires at annual intervals over 4 years. Magnetic resonance imaging-based cartilage thickness change in the medial femorotibial compartment (MFTC) over 4 years was the main outcome. Read More

J Orthop Res 2019 Jan 29;37(1):124-130. Epub 2018 Oct 29.

Wolf Orthopaedic Biomechanics Laboratory, Fowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada.

The purpose of the present study was to compare bilateral external knee moments during gait in patients with concomitant medial compartment knee OA, varus alignment and chronic anterior cruciate ligament (ACL) deficiency who underwent either medial opening-wedge high tibial osteotomy alone (HTO) or simultaneous HTO and ACL reconstruction (HTO-ACLR). Fifty-two patients (26 matched pairs) completed 3D gait analysis preoperatively and at a minimum 5 years postoperatively. Patients were matched for preoperative age, sex, body mass index and magnitude of correction. Read More

Arthritis Care Res (Hoboken) 2018 Oct 8. Epub 2018 Oct 8.

Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA, USA.

Objective: Reports on quadriceps weakness as a risk factor for incident and progressive knee osteoarthritis are conflicting, potentially due to differing effects of muscle strength on patellofemoral and tibiofemoral compartments. This study aimed to examine the sex-specific relation of quadriceps strength to worsening patellofemoral and tibiofemoral cartilage damage over 84-months.

Methods: The Multicenter Osteoarthritis Study (MOST) is a cohort study of individuals with or at risk for knee osteoarthritis. Read More

Arthroscopy 2018 Nov 3;34(11):3073-3079. Epub 2018 Oct 3.

Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: To compare the accuracy of plain radiography and computed tomography (CT) in detecting lateral hinge fractures and to identify predictive factors of the lateral hinge fractures after open wedge high tibial osteotomy (HTO).

Methods: This study included patients who underwent isolated primary open wedge HTO for medial compartment degenerative arthritis from 2015 to 2016 and were evaluated by postoperative CT scans and followed for a minimum of 1 year. This study involved 48 patients (48 knees) undergoing open wedge HTO for primary medial osteoarthritis. Read More

J Knee Surg 2018 Oct 3. Epub 2018 Oct 3.

Department of Orthopaedic Surgery, Anderson Orthopaedic Clinic, Alexandria, Virginia.

Partial knee arthroplasty is a procedure with long-term successful outcomes. However, there are several potential complications including retained cement fragments, bearing dislocation, infection, component loosening, medial collateral ligament injury, and overcorrection, leading to progressive arthritis. Periprosthetic fracture is an uncommon complication, with multiple reports showing an incidence of less than 1%. Read More

J Rheumatol 2019 Feb 1;46(2):198-203. Epub 2018 Oct 1.

From the Department of Medicine, the Division of Rheumatology, the Department of Radiology and the School of Population and Public Health, University of British Columbia, Vancouver; Arthritis Research Canada, Vancouver; Canadian Institutes of Health Research HIV Trials Network, Vancouver; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada; Department of Radiology, Boston University Medical Center, Boston, Massachusetts, USA.

Objective: To determine whether baseline quadriceps weakness predicts cartilage loss assessed on magnetic resonance imaging (MRI).

Methods: Subjects aged 40-79 with knee pain (n = 163) were recruited from a random population sample and examined for quadriceps weakness with manual isometric strength testing, using a 3-point scoring system (0 = poor resistance, 1 = moderate resistance, 2 = full resistance), which was dichotomized as normal (grade 2) versus weak (grade 0/1). MRI of the more symptomatic knee was obtained at baseline and at mean of 3. Read More

Hosp Pract (1995) 2019 Feb 29;47(1):1-5. Epub 2018 Sep 29.

b Department of Physical Medicine and Rehabilitation , La Paz University Hospital-IdiPaz , Madrid , Spain.

Objectives: Taking into account that the role of orthoses in patients with knee osteoarthritis (OA) is unclear and controversial, the purpose of this article is to review recent literature with the aim of answering the following question: What is the current role of orthoses in the treatment of knee OA?

Methods: A Cochrane Library and PubMed (MEDLINE) search related to the role of orthoses in knee OA was performed.

Results: Unloader braces decrease the adduction moment of the knee. In patients with varus medial compartment knee OA bracing is beneficial for pain, stiffness, function and quality of life (low grade of evidence). Read More

Vet Surg 2018 Oct 21;47(7):958-962. Epub 2018 Sep 21.

Austin Veterinary Emergency and Specialty Center, Austin, Texas.

Objective: To describe articular cartilage (AC) lesions associated with complete lateral meniscal tears in dogs.

Study Design: Observational series.

Animals: Seventeen dogs with arthroscopic evidence of a complete lateral meniscal tear and associated AC lesions. Read More

J Orthop Res 2019 Jan 9;37(1):104-112. Epub 2018 Oct 9.

Biomechanics and Movement Science, University of Delaware, 540 South College Avenue, Newark 19713, Delaware.

The mechanism of knee osteoarthritis development after anterior cruciate ligament injuries is poorly understood. The objective of this study was to evaluate knee gait variables, muscle co-contraction indices and knee joint loading in young subjects with anterior cruciate ligament deficiency (ACLD, n = 36), versus control subjects (n = 12). A validated, electromyography-informed model was used to estimate joint loading. Read More

Medicine (Baltimore) 2018 Aug;97(35):e11943

Nuclear Medicine Department, University Hospital Morvan, Brest Cedex.

The aim of the study was to evaluate the interest of quantitative bone SPECT-CT in the preoperative assessment of knee osteoarthritis (OA) before unicompartmental knee arthroplasty (UKA).Patients eligible for UKA were prospectively included in 2 centers and underwent a preoperative SPECT-CT. Images were reconstructed with an OSEM, an OSCGM (allowing SUV quantification) and an enhanced OSCGM (containing uptakes to bones) algorithms. Read More

Orthop Surg 2018 Aug;10(3):227-234

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK.

Objectives: Knee osteoarthritis (OA) is a prevalent disease in the elderly, causing pain and contributing to poor quality of life. Surgical intervention, such as knee arthroplasty, can be used in those with end-stage knee OA. Total knee arthroplasty (TKA) is one of the most common surgical procedures for end-stage knee OA, with promising clinical outcomes. Read More

BMJ Case Rep 2018 Aug 27;2018. Epub 2018 Aug 27.

Department of Orthopaedic Surgery, Yawata Medical Center, Komatsu, Ishikawa, Japan.

A 70-year-old man who was treated with a closed-wedge high tibial osteotomy (HTO) had recurrent right medial knee pain 12 years after the initial osteotomy. We planned a recorrection osteotomy because the patient led an active lifestyle, had well-preserved range of motion and the lateral compartment was still intact. According to preoperative deformity analysis, which indicated a tibia in slight valgus and a femur in moderate varus, recorrection of the distal femur was chosen. Read More

J Arthroplasty 2018 11 29;33(11):3441-3447. Epub 2018 Jul 29.

Athens Orthopedic Clinic, Athens, GA; Department of Kinesiology, University of Georgia, Athens, GA.

Background: Medial unicompartmental knee arthroplasty (UKA) has been a successful option for treatment of arthritis in patients with a healthy lateral compartment. However, lateral UKA is less common and results are less consistent. The purpose of this study is to compare progression of radiographically evident osteoarthritis in unoperated compartments during 5 years after lateral and medial UKA. Read More

Clin Rheumatol 2018 Oct 16;37(10):2893-2896. Epub 2018 Aug 16.

Department of Anatomy, School of Medicine, University of Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.

Knee osteoarthritis (OA) is one of the most common musculoskeletal diseases and osteophytes area frequent radiographic feature of knee OA. The osteophyte structure in knee OA, however, is not well elucidated. This study aimed to clarify the three-dimensional microstructural characteristics of osteophytes in the medial compartment of the knee in knee OA patients using micro-computed tomography (micro-CT). Read More

Knee 2018 Oct 13;25(5):746-756. Epub 2018 Aug 13.

Department of Radiology, Cumming School of Medicine, University of Calgary, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Canada. Electronic address:

Background: Anterior cruciate ligament (ACL) tears increase the risk of developing knee osteoarthritis. This risk increases further with concurrent meniscus injury. The role of bone changes during knee osteoarthritis development are not well-understood, but may be important to its etiology. Read More

J Knee Surg 2018 Aug 13. Epub 2018 Aug 13.

Department of Joint Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

This article compares the long-term outcomes of closing-wedge osteotomy (CWO) and opening-wedge osteotomy (OWO) in the treatment of unicompartmental medial osteoarthritis with varus deformity. This study included 79 patients who underwent high tibial osteotomy (HTO) between 2002 and 2008. Pre- and postoperative radiography and computed tomography were used to evaluate the posterior tibial slope, the patellar height, the tibiofemoral angle, and the lateral and medial tibiofemoral joint space. Read More

Bone Joint J 2018 08;100-B(8):1033-1042

University College London Hospitals, The Princess Grace Hospital, and The NIHR Biomedical Research Centre at UCLH, London, UK.

Aims: The primary aim of this study was to determine the surgical team's learning curve for introducing robotic-arm assisted unicompartmental knee arthroplasty (UKA) into routine surgical practice. The secondary objective was to compare accuracy of implant positioning in conventional jig-based UKA versus robotic-arm assisted UKA.

Patients And Methods: This prospective single-surgeon cohort study included 60 consecutive conventional jig-based UKAs compared with 60 consecutive robotic-arm assisted UKAs for medial compartment knee osteoarthritis. Read More

BMC Musculoskelet Disord 2018 Jul 27;19(1):266. Epub 2018 Jul 27.

Center for Joint Disease, Chonnam National University Hwasun Hospital, 160, Ilsim-Ri, Hwasun-Eup, Hwasun-Gun, Jeonnam, 519-809, South Korea.

Background: Soft tissue balancing which is above all most important factor of total knee arthroplasty, has been performed by subjective methods. Recently objective orthosensor has been developed for compartment pressure measurement. The purpose of this study was: (1) to quantify the compartment pressure of the joint throughout the range of motion during TKA using orthosensor, (2) to determine the usefulness of orthosensor by analyzing correlation between the pressure in both compartment with initial trial and after final implantation, and (3) to evaluate the types and effectiveness of additional ligament balancing procedures to compartment pressure. Read More

Osteoarthritis Cartilage 2018 Nov 20;26(11):1562-1569. Epub 2018 Jul 20.

The University of Arizona Arthritis Center, Tucson, AZ, USA; Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, USA. Electronic address:

Objective: Magnetic resonance imaging (MRI)-detected structural features are associated with increased risk of radiographic osteoarthritis (ROA). Specific mitochondrial DNA (mtDNA) haplogroups have been associated with incident ROA. Our objective was to compare the presence of MRI-detected structural features across mtDNA haplogroups among knees that developed incident ROA. Read More

Arch Orthop Trauma Surg 2018 Oct 19;138(10):1463-1469. Epub 2018 Jul 19.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Yildirim Beyazit University, Bilkent, Ankara, Turkey.

Background: UKA necessitates a learning period. From this point of view, it would be logical to prefer the design that tolerates suboptimal tibial rotations better, especially for inexperienced surgeons. The aim of this study was to evaluate and compare the clinical and radiological results of mobile-bearing and fix-bearing UKA designs in case of suboptimal tibial rotations. Read More

BMC Musculoskelet Disord 2018 Jul 18;19(1):228. Epub 2018 Jul 18.

Center for Joint Disease, Chonnam National University Hwasun Hospital, Hwasun, South Korea.

Background: We aimed to evaluate clinical and radiological results after simultaneous open-wedge high tibial osteotomy (HTO) and anterior cruciate ligament (ACL) reconstruction in patients with ACL deficiency combined with medial uni-compartmental osteoarthritis (OA) and varus deformity.

Methods: This retrospective study was performed using data collected from 2005 to 2011 on a total of 24 patients who were diagnosed with ACL injury and medial unicompartmental OA with varus deformity, and who subsequently underwent simultaneous open-wedge HTO and arthroscopic ACL reconstruction. The mean follow-up duration was 5. Read More

Knee 2018 Oct 17;25(5):825-833. Epub 2018 Jul 17.

Funktionsbereich Bewegungsanalytik, IEMM, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, Gebäude D3, 48129 Münster, Germany.

Background: Knee osteoarthritis (KOA) is the most common form of arthritis with an estimated lifetime prevalence of 45%. The use of orthotic devices is a generally accepted conservative therapy in KOA. A new conservative treatment is an ankle-foot orthosis (AFO); however, studies on the biomechanical effects are limited. Read More

Rheumatology (Oxford) 2018 10;57(10):1851-1860

Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Canada.

Objective: This study explored the role of the adipokine adipsin in OA.

Methods: Control and OA articular tissues, cells and serum were obtained from human individuals. Serum adipsin levels of human OA individuals were compared with cartilage volume loss as assessed by MRI at 48 months. Read More

Knee 2018 Oct 20;25(5):856-865. Epub 2018 Jun 20.

Department of Orthopaedic Surgery, Gachon University Gil Medical Center, Gachon University College of Medicine, 21, Namdong-daero 774 beon-gil, Namdong-gu, Incheon, Republic of Korea. Electronic address:

Background: Whether osteoarthritic patients with mild varus deformity can be indicated for high tibial osteotomy (HTO) is not established. We examined the preoperative characteristics and postoperative outcomes of HTO in patients with mild genu varum compared to patients with greater varus deformity.

Methods: Seventy-one patients who underwent HTO were included in this retrospective study. Read More

Ann Biomed Eng 2018 Nov 19;46(11):1785-1796. Epub 2018 Jun 19.

School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.

Pressure distribution of the native ovine knee meniscus was compared to a medial meniscectomy and three treatment conditions including a suture reattachment of the native tissue, an allograft, and a novel thermoplastic elastomer hydrogel (TPE) construct. The objective of this study was to assess the efficacy of a novel TPE hydrogel construct at restoring joint pressure and distribution. Limbs were loaded in uniaxial compression at 45°, 60°, and 75° flexion and from 0 to 181 kg. Read More

Arthrosc Tech 2018 May 16;7(5):e511-e515. Epub 2018 Apr 16.

Sportsclinic Cologne, University of Witten/Herdecke, Cologne-Merheim-Medical-Centre, Cologne, Germany.

The biomechanical consequences of a tear of the posterior root of the medial meniscus are comparable to that of a complete meniscectomy. The integrity of the meniscal roots is crucial to enable the important function of load sharing and shock absorption. An untreated root tear leads to extrusion and loss of function of the meniscus causing early degenerative arthritis of the respective knee compartment. Read More

Arthrosc Tech 2018 May 2;7(5):e429-e435. Epub 2018 Apr 2.

Orthopaedic Specialty Clinic, Pune, India.

Medial meniscus posterior root tears are common injuries, especially in the Asian world. This injury must be repaired where indicated to restore knee biomechanics and prevent arthritis. Suturing the meniscus using suture tapes provides good hold of the tissue. Read More

Clin Calcium 2018;28(6):832-839

Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Japan.

Unicompartmental knee arthroplasty(UKA)has been performed for the treatment of isolated unicompartmental knee disease. Satisfactory results have been achieved when used in the medial compartment and strict inclusion criteria are followed. UKA is one of the minimally invasive surgeries and suitable for elderly severe knee osteoarthritis(OA)patients with a lot of complication. Read More

J Int Med Res 2018 Aug 30;46(8):3114-3123. Epub 2018 May 30.

1 Department of Orthopedic Surgery, The Third Hospital of Hebei Medical University (Hebei Orthopedic Hospital), Shijiazhuang, Hebei, P.R. China.

Objectives This study was performed to explore the mechanism of proximal fibular osteotomy (PFO) for treatment of medial compartment knee osteoarthritis (OA) and evaluate the relevant factors influencing the treatment outcome. Methods Fifty-two patients with medial compartment knee OA with varus deformities were prospectively selected. Radiographs were obtained preoperatively and postoperatively. Read More

J Arthroplasty 2018 09 4;33(9):2851-2857. Epub 2018 May 4.

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Background: The importance of medial compartment stability is recognized in total knee arthroplasty (TKA). To manage the medial extension-flexion gap, the posterior reference position can be changed from conventional posterior center to posterior medial in measured resection techniques. This study aimed to compare the intraoperative soft tissue balance and rotational kinematics between the posterior medial and posterior center reference groups. Read More