1,566 results match your criteria Medial Compartment Arthritis


An assessment of early functional rehabilitation and hospital discharge in conventional versus robotic-arm assisted unicompartmental knee arthroplasty.

Bone Joint J 2019 Jan;101-B(1):24-33

University College London Hospitals; The Princess Grace Hospital; The NIHR Biomedical Research Centre at UCLH, London, UK.

Aims: The objectives of this study were to compare postoperative pain, analgesia requirements, inpatient functional rehabilitation, time to hospital discharge, and complications in patients undergoing conventional jig-based unicompartmental knee arthroplasty (UKA) versus robotic-arm assisted UKA.

Patients And Methods: This prospective cohort study included 146 patients with symptomatic medial compartment knee osteoarthritis undergoing primary UKA performed by a single surgeon. This included 73 consecutive patients undergoing conventional jig-based mobile bearing UKA, followed by 73 consecutive patients receiving robotic-arm assisted fixed bearing UKA. Read More

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http://dx.doi.org/10.1302/0301-620X.101B1.BJJ-2018-0564.R2DOI Listing
January 2019

Lateral Unicompartmental Knee Arthroplasty Utilizing a Modified Surgical Technique and Specifically Adapted Fixed-Bearing Implant.

Surg Technol Int 2018 Dec 20;34. Epub 2018 Dec 20.

Joint Implant Surgeons, Inc., New Albany, Ohio, White Fence Surgical Suites, LLC New Albany, Ohio, Mount Carmel Health System, Columbus, Ohio.

Background: Treatment of isolated lateral compartment arthritic disease with partial knee arthroplasty remains underutilized in comparison to medial unicompartmental arthroplasty. This study examines the survival and outcome of lateral unicompartmental arthroplasty utilizing the first implant specifically developed for the lateral compartment.

Materials And Methods: A retrospective review was performed to detect lateral unicompartmental arthroplasty procedures performed in our practice between January 2013 and May 2016. Read More

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December 2018
4 Reads

Diffusion tensor imaging and diffusion modeling: Application to monitoring changes in the medial gastrocnemius in disuse atrophy induced by unilateral limb suspension.

J Magn Reson Imaging 2018 Dec 19. Epub 2018 Dec 19.

Muscle Imaging and Modeling Lab, Department of Radiology, UC San Diego, San Diego, California, USA.

Background: Diffusion tensor imaging (DTI) assesses underlying tissue microstructure, and has been applied to studying skeletal muscle. Unloading of the lower leg causes decreases in muscle force, mass, and muscle protein synthesis as well as changes in muscle architecture.

Purpose: To monitor the change in DTI indices in the medial gastrocnemius (MG) after 4-week unilateral limb suspension (ULLS) and to explore the feasibility of extracting tissue microstructural parameters based on a two-compartment diffusion model. Read More

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http://dx.doi.org/10.1002/jmri.26295DOI Listing
December 2018
1 Read

Quadriceps weakness associates with greater T1ρ relaxation time in the medial femoral articular cartilage 6 months following anterior cruciate ligament reconstruction.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 17. Epub 2018 Dec 17.

Department of Orthopaedics, University of North Carolina at Chapel Hill, 102 Mason Farm Rd # 2, Chapel Hill, NC, 27599, USA.

Purpose: Quadriceps weakness following anterior cruciate ligament reconstruction (ACLR) is linked to decreased patient-reported function, altered lower extremity biomechanics and tibiofemoral joint space narrowing. It remains unknown if quadriceps weakness is associated with early deleterious changes to femoral cartilage composition that are suggestive of posttraumatic osteoarthritis development. The purpose of the cross-sectional study was to determine if quadriceps strength was associated with T1ρ relaxation times, a marker of proteoglycan density, of the articular cartilage in the medial and lateral femoral condyles 6 months following ACLR. Read More

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http://dx.doi.org/10.1007/s00167-018-5290-yDOI Listing
December 2018
1 Read

Cartilage repair surgery prevents progression of knee degeneration.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 12. Epub 2018 Dec 12.

Musculoskeletal and Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.

Purpose: To investigate, whether cartilage repair surgery for focal osteochondral defects at the knee results in less degenerative changes over 6 years in a MR imaging follow-up than morphologically initially identical defects in non-operated control subjects from the osteoarthritis initiative (OAI).

Methods: A total of 32 individuals received baseline and follow-up MRI. In n = 16 patients with cartilage repair [osteochondral autograft transfer system (OATS), n = 12; spongiosa-augmented matrix-associated autologous chondrocyte implantation (MACI), n = 4] MRI was performed preoperatively and after 5. Read More

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http://dx.doi.org/10.1007/s00167-018-5321-8DOI Listing
December 2018

Lateral cartilage defects and medial subchondral surface ratio are associated with knee-related disability.

J Orthop Res 2018 Nov 27. Epub 2018 Nov 27.

Department of Orthopaedics, The Ohio State University Wexner Medical Center, 2835 Fred Taylor Dr, Columbus, Ohio, 43202.

We sought to determine the relationship between (i) full-thickness cartilage defects and tibiofemoral subchondral surface ratio (SSR) and (ii) disability and quality of life in patients with mild radiographic osteoarthritis (OA) (Kellgren-Lawrence grade 2) or without radiographic OA (Kellgren-Lawrence grades 0 or 1)? A total of 642 participants from the Osteoarthritis Initiative (OAI) with baseline knee MRIs and a Kellgren-Lawrence grade 2 or less on both bilateral screening radiographs were included. The independent relationship was assessed between (i) full-thickness cartilage defect presence and tibiofemoral SSR and (ii) Knee Injury and Osteoarthritis Outcome Score (KOOS) quality of life (QOL), KOOS function in sports and recreation (KOOS-sport/rec), and Western Ontario and McMaster Universities Arthritis Index (WOMAC) disability score after adjustment for relevant confounders with multivariate regression modeling. The prevalence of medial full-thickness defects was 10. Read More

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http://doi.wiley.com/10.1002/jor.24187
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http://dx.doi.org/10.1002/jor.24187DOI Listing
November 2018
6 Reads

Comparison between kinetic and kinetic-kinematic driven knee joint finite element models.

Sci Rep 2018 Nov 26;8(1):17351. Epub 2018 Nov 26.

Department of Applied Physics, University of Eastern Finland, POB 1627, FI-70211, Kuopio, Finland.

Use of knee joint finite element models for diagnostic purposes is challenging due to their complexity. Therefore, simpler models are needed for studies where a high number of patients need to be analyzed, without compromising the results of the model. In this study, more complex, kinetic (forces and moments) and simpler, kinetic-kinematic (forces and angles) driven finite element models were compared during the stance phase of gait. Read More

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http://dx.doi.org/10.1038/s41598-018-35628-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255758PMC
November 2018
1 Read

Minimally invasive Oxford unicompartmental knee arthroplasty ensures excellent functional outcome and high survivorship in the long term.

Knee Surg Sports Traumatol Arthrosc 2018 Nov 21. Epub 2018 Nov 21.

Center for Orthopaedics and Trauma Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, 69118, Heidelberg, Germany.

Purpose: Whether unicompartimental or total knee arthroplasty is superior for treatment of anteromedial knee osteoarthritis, is still uncertain. Therefore, the purpose of this study was to evaluate clinical and radiological outcome as well as long-term survivorship of medial Oxford unicompartmental knee arthroplasty (OUKA) at an independent center with a minimum follow-up of 10 years.

Methods: This single-center retrospective cohort study reports the 10-15 years follow-up results of 113 consecutive patients (126 knees) after medial OUKA. Read More

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http://dx.doi.org/10.1007/s00167-018-5299-2DOI Listing
November 2018
8 Reads

Lower patient-reported function at 2 years is associated with elevated knee cartilage T1rho and T2 relaxation times at 5 years in young athletes after ACL reconstruction.

Knee Surg Sports Traumatol Arthrosc 2018 Nov 16. Epub 2018 Nov 16.

School of Health and Rehabilitation Sciences, The Ohio State University, 453 W 10th Avenue, Columbus, OH, USA.

Purpose: The purpose was to test the following hypotheses: (1) magnetic resonance imaging (MRI) markers of early knee cartilage degeneration would be present in the involved limb of young athletes after anterior cruciate ligament reconstruction (ACLR) and (2) poor knee function would be associated with MRI markers of cartilage degeneration.

Methods: Twenty-five young athletes after primary, unilateral ACLR (mean age, 16.7 years) were followed to 5-year post-return-to-sport (RTS) clearance, as a part of a larger, prospective cohort study in young athletes post-ACLR. Read More

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http://link.springer.com/10.1007/s00167-018-5291-x
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http://dx.doi.org/10.1007/s00167-018-5291-xDOI Listing
November 2018
5 Reads

Hip Muscle Strengthening for Knee Osteoarthritis: A Systematic Review of Literature.

J Geriatr Phys Ther 2018 Nov 6. Epub 2018 Nov 6.

Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Karnataka, India.

Background And Purpose: Osteoarthritis (OA) of the knee joint results in chronic pain and functional decline among older adults. Hip muscle weakness has been observed in persons with knee OA and is claimed to increase the medial compartment loading on the knee joint. Although individual studies are available, no review has yet integrated the literature on the benefits of hip muscle strengthening for persons with knee OA. Read More

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http://Insights.ovid.com/crossref?an=00139143-900000000-9969
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http://dx.doi.org/10.1519/JPT.0000000000000214DOI Listing
November 2018
11 Reads

Superolateral Hoffa's Fat Pad Edema and Trochlear Sulcal Angle Are Associated With Isolated Medial Patellofemoral Compartment Osteoarthritis.

Can Assoc Radiol J 2018 Nov;69(4):450-457

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Orthopedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

Purpose: To evaluate whether mediopatellar plica and knee morphometric measurements obtained from magnetic resonance imaging (MRI) studies are associated with isolated medial patellofemoral osteoarthritis in young adults.

Methods: MRI studies from 60 patients with isolated medial patellofemoral osteoarthritis and 90 control patients with normal knee MRI studies were reviewed. The presence of mediopatellar plica, the presence of edema in the superolateral aspect of Hoffa's fat pad and suprapatellar fat pad, quadriceps and patellar tendinosis, and axial and sagittal alignment of the patellar and trochlear morphology were assessed using MRI. Read More

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http://dx.doi.org/10.1016/j.carj.2018.07.010DOI Listing
November 2018
1 Read

Diabetics show accelerated progression of knee cartilage and meniscal lesions: data from the osteoarthritis initiative.

Skeletal Radiol 2018 Oct 24. Epub 2018 Oct 24.

Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.

Objective: To investigate whether subjects with diabetes show accelerated knee joint structural degeneration over 4 years compared to diabetes-free controls.

Materials And Methods: Two hundred forty-four participants with diabetes were selected from the Osteoarthritis Initiative cohort and matched with 244 diabetes-free controls. 3. Read More

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http://link.springer.com/10.1007/s00256-018-3088-0
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http://dx.doi.org/10.1007/s00256-018-3088-0DOI Listing
October 2018
6 Reads

Moderate physical activity may prevent cartilage loss in women with knee osteoarthritis: data from the Osteoarthritis Initiative.

Arthritis Care Res (Hoboken) 2018 Oct 19. Epub 2018 Oct 19.

Institute of Anatomy, Paracelsus Medical University Salzburg & Nuremberg, Salzburg, Austria.

Objective: To examine the impact of physical activity (PA) on cartilage thickness loss in knee osteoarthritis (KOA).

Methods: 689 participants with radiographic KOA (Kellgren/Lawrence grade ≥2) at baseline, from the Osteoarthritis Initiative completed the Physical Activity Scale for the Elderly (PASE) questionnaires at annual intervals over four years. Magnetic resonance imaging-based cartilage thickness change in the medial femorotibial compartment (MFTC) over four years was the main outcome. Read More

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http://doi.wiley.com/10.1002/acr.23791
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http://dx.doi.org/10.1002/acr.23791DOI Listing
October 2018
13 Reads

Gait biomechanics after combined HTO-ACL reconstruction versus HTO alone: A matched cohort study.

J Orthop Res 2018 Oct 10. Epub 2018 Oct 10.

Wolf Orthopaedic Biomechanics Laboratory, Fowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada.

The purpose of the present study was to compare bilateral external knee moments during gait in patients with concomitant medial compartment knee OA, varus alignment and chronic anterior cruciate ligament (ACL) deficiency who underwent either medial opening-wedge high tibial osteotomy alone (HTO) or simultaneous HTO and ACL reconstruction (HTO-ACLR). Fifty-two patients (26 matched pairs) completed 3D gait analysis preoperatively and at a minimum 5 years postoperatively. Patients were matched for preoperative age, sex, body mass index and magnitude of correction. Read More

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http://doi.wiley.com/10.1002/jor.24157
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http://dx.doi.org/10.1002/jor.24157DOI Listing
October 2018
2 Reads

The sex-specific influence of quadriceps weakness on worsening patellofemoral and tibiofemoral cartilage damage: the MOST Study.

Arthritis Care Res (Hoboken) 2018 Oct 8. Epub 2018 Oct 8.

Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA, USA.

Objective: Reports on quadriceps weakness as a risk factor for incident and progressive knee osteoarthritis are conflicting, potentially due to differing effects of muscle strength on patellofemoral and tibiofemoral compartments. This study aimed to examine the sex-specific relation of quadriceps strength to worsening patellofemoral and tibiofemoral cartilage damage over 84-months.

Methods: The Multicenter Osteoarthritis Study (MOST) is a cohort study of individuals with or at risk for knee osteoarthritis. Read More

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http://doi.wiley.com/10.1002/acr.23773
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http://dx.doi.org/10.1002/acr.23773DOI Listing
October 2018
7 Reads

Predictive Factors for and Detection of Lateral Hinge Fractures Following Open Wedge High Tibial Osteotomy: Plain Radiography Versus Computed Tomography.

Arthroscopy 2018 Nov 3;34(11):3073-3079. Epub 2018 Oct 3.

Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: To compare the accuracy of plain radiography and computed tomography (CT) in detecting lateral hinge fractures and to identify predictive factors of the lateral hinge fractures after open wedge high tibial osteotomy (HTO).

Methods: This study included patients who underwent isolated primary open wedge HTO for medial compartment degenerative arthritis from 2015 to 2016 and were evaluated by postoperative CT scans and followed for a minimum of 1 year. This study involved 48 patients (48 knees) undergoing open wedge HTO for primary medial osteoarthritis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07498063183052
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http://dx.doi.org/10.1016/j.arthro.2018.06.041DOI Listing
November 2018
2 Reads

Periprosthetic Fracture following Partial Knee Arthroplasty.

J Knee Surg 2018 Oct 3. Epub 2018 Oct 3.

Department of Orthopaedic Surgery, Anderson Orthopaedic Clinic, Alexandria, Virginia.

Partial knee arthroplasty is a procedure with long-term successful outcomes. However, there are several potential complications including retained cement fragments, bearing dislocation, infection, component loosening, medial collateral ligament injury, and overcorrection, leading to progressive arthritis. Periprosthetic fracture is an uncommon complication, with multiple reports showing an incidence of less than 1%. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1672204
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http://dx.doi.org/10.1055/s-0038-1672204DOI Listing
October 2018
2 Reads

Quadriceps Weakness and the Risk of Knee Cartilage Loss Seen on Magnetic Resonance Imaging in a Population-based Cohort with Knee Pain.

J Rheumatol 2018 Oct 1. Epub 2018 Oct 1.

From the Department of Medicine, the Division of Rheumatology, the Department of Radiology and the School of Population and Public Health, University of British Columbia, Vancouver; Arthritis Research Canada, Vancouver; Canadian Institutes of Health Research HIV Trials Network, Vancouver; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada; Department of Radiology, Boston University Medical Center, Boston, Massachusetts, USA. This research was funded by grants from the Canadian Institutes of Health Research (89890, 89997), the Canadian Arthritis Network (01-MNO-09N), and the Arthritis Society (TAS04/0063). Dr. Cibere's work was supported by an investigator award from the Arthritis Society (INS-12-027). C. Chin, MD, FRCPC, Division of Rheumatology, University of British Columbia; E.C. Sayre, PhD, Research Associate, Arthritis Research Canada; A. Guermazi, MD, Professor, Department of Radiology, Boston University Medical Center; S. Nicolaou, MD, Assistant Professor, Department of Radiology, University of British Columbia (UBC), Director of Emergency/Trauma Imaging, Vancouver General Hospital; H. Wong, PhD, Associate Professor, School of Population and Public Health, UBC, and Associate Head, Data and Methodology, CIHR Canadian HIV Trials Network; A. Thorne, MSc, Senior Biostatistician, CIHR Canadian HIV Trials Network, School of Population and Public Health, UBC; J. Singer, PhD, Professor, School of Population and Public Health, UBC, and Centre for Health Evaluation and Outcome Sciences; J.A. Kopec, MD, MSc, PhD, Associate Professor, School of Population and Public Health, UBC, and Research Scientist, Arthritis Research Canada; J.M. Esdaile, MD, MPH, Professor, Department of Medicine, UBC, and Scientific Director, Arthritis Research Canada; J. Cibere, MD, PhD, Associate Professor, Department of Medicine, UBC, and Senior Research Scientist, Arthritis Research Canada. Address correspondence to Dr. C. Chin, 802-1200 Burrard St., Vancouver, British Columbia V6Z 2C7, Canada. E-mail: Accepted for publication July 18, 2018.

Objective: To determine whether baseline quadriceps weakness predicts cartilage loss assessed on magnetic resonance imaging (MRI).

Methods: Subjects aged 40-79 with knee pain (n = 163) were recruited from a random population sample and examined for quadriceps weakness with manual isometric strength testing, using a 3-point scoring system (0 = poor resistance, 1 = moderate resistance, 2 = full resistance), which was dichotomized as normal (grade 2) versus weak (grade 0/1). MRI of the more symptomatic knee was obtained at baseline and at mean of 3. Read More

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http://dx.doi.org/10.3899/jrheum.170875DOI Listing
October 2018
6 Reads

Articular cartilage lesions associated with complete lateral meniscal tears in the dog.

Vet Surg 2018 Oct 21;47(7):958-962. Epub 2018 Sep 21.

Austin Veterinary Emergency and Specialty Center, Austin, Texas.

Objective: To describe articular cartilage (AC) lesions associated with complete lateral meniscal tears in dogs.

Study Design: Observational series.

Animals: Seventeen dogs with arthroscopic evidence of a complete lateral meniscal tear and associated AC lesions. Read More

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http://dx.doi.org/10.1111/vsu.12961DOI Listing
October 2018
3 Reads

High muscle co-contraction does not result in high joint forces during gait in anterior cruciate ligament deficient knees.

J Orthop Res 2018 Sep 19. Epub 2018 Sep 19.

Biomechanics and Movement Science, University of Delaware, 540 South College Avenue, Newark 19713, Delaware.

The mechanism of knee osteoarthritis development after anterior cruciate ligament injuries is poorly understood. The objective of this study was to evaluate knee gait variables, muscle co-contraction indices and knee joint loading in young subjects with anterior cruciate ligament deficiency (ACLD, n = 36), versus control subjects (n = 12). A validated, electromyography-informed model was used to estimate joint loading. Read More

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http://dx.doi.org/10.1002/jor.24141DOI Listing
September 2018
1 Read

Clinical interest of quantitative bone SPECT-CT in the preoperative assessment of knee osteoarthritis.

Medicine (Baltimore) 2018 Aug;97(35):e11943

Nuclear Medicine Department, University Hospital Morvan, Brest Cedex.

The aim of the study was to evaluate the interest of quantitative bone SPECT-CT in the preoperative assessment of knee osteoarthritis (OA) before unicompartmental knee arthroplasty (UKA).Patients eligible for UKA were prospectively included in 2 centers and underwent a preoperative SPECT-CT. Images were reconstructed with an OSEM, an OSCGM (allowing SUV quantification) and an enhanced OSCGM (containing uptakes to bones) algorithms. Read More

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http://dx.doi.org/10.1097/MD.0000000000011943DOI Listing
August 2018
8 Reads

Patterns of Compartment Involvement in End-stage Knee Osteoarthritis in a Chinese Orthopedic Center: Implications for Implant Choice.

Orthop Surg 2018 Aug;10(3):227-234

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK.

Objectives: Knee osteoarthritis (OA) is a prevalent disease in the elderly, causing pain and contributing to poor quality of life. Surgical intervention, such as knee arthroplasty, can be used in those with end-stage knee OA. Total knee arthroplasty (TKA) is one of the most common surgical procedures for end-stage knee OA, with promising clinical outcomes. Read More

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http://dx.doi.org/10.1111/os.12395DOI Listing
August 2018
3 Reads

Additional distal femoral osteotomy for insufficient correction after high tibial osteotomy.

BMJ Case Rep 2018 Aug 27;2018. Epub 2018 Aug 27.

Department of Orthopaedic Surgery, Yawata Medical Center, Komatsu, Ishikawa, Japan.

A 70-year-old man who was treated with a closed-wedge high tibial osteotomy (HTO) had recurrent right medial knee pain 12 years after the initial osteotomy. We planned a recorrection osteotomy because the patient led an active lifestyle, had well-preserved range of motion and the lateral compartment was still intact. According to preoperative deformity analysis, which indicated a tibia in slight valgus and a femur in moderate varus, recorrection of the distal femur was chosen. Read More

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http://dx.doi.org/10.1136/bcr-2018-224514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119394PMC
August 2018
2 Reads

Disease Progression After Lateral and Medial Unicondylar Knee Arthroplasty.

J Arthroplasty 2018 Nov 29;33(11):3441-3447. Epub 2018 Jul 29.

Athens Orthopedic Clinic, Athens, GA; Department of Kinesiology, University of Georgia, Athens, GA.

Background: Medial unicompartmental knee arthroplasty (UKA) has been a successful option for treatment of arthritis in patients with a healthy lateral compartment. However, lateral UKA is less common and results are less consistent. The purpose of this study is to compare progression of radiographically evident osteoarthritis in unoperated compartments during 5 years after lateral and medial UKA. Read More

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http://dx.doi.org/10.1016/j.arth.2018.07.019DOI Listing
November 2018
4 Reads

Microstructure of osteophytes in medial knee osteoarthritis.

Clin Rheumatol 2018 Oct 16;37(10):2893-2896. Epub 2018 Aug 16.

Department of Anatomy, School of Medicine, University of Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.

Knee osteoarthritis (OA) is one of the most common musculoskeletal diseases and osteophytes area frequent radiographic feature of knee OA. The osteophyte structure in knee OA, however, is not well elucidated. This study aimed to clarify the three-dimensional microstructural characteristics of osteophytes in the medial compartment of the knee in knee OA patients using micro-computed tomography (micro-CT). Read More

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http://dx.doi.org/10.1007/s10067-018-4262-4DOI Listing
October 2018
1.774 Impact Factor

A study of the relationship between meniscal injury and bone microarchitecture in ACL reconstructed knees.

Knee 2018 Oct 13;25(5):746-756. Epub 2018 Aug 13.

Department of Radiology, Cumming School of Medicine, University of Calgary, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Canada. Electronic address:

Background: Anterior cruciate ligament (ACL) tears increase the risk of developing knee osteoarthritis. This risk increases further with concurrent meniscus injury. The role of bone changes during knee osteoarthritis development are not well-understood, but may be important to its etiology. Read More

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http://dx.doi.org/10.1016/j.knee.2018.07.004DOI Listing
October 2018
20 Reads

Clinical Outcomes of Closing- and Opening-Wedge High Tibial Osteotomy for Treatment of Anteromedial Unicompartmental Knee Osteoarthritis.

J Knee Surg 2018 Aug 13. Epub 2018 Aug 13.

Department of Joint Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

This article compares the long-term outcomes of closing-wedge osteotomy (CWO) and opening-wedge osteotomy (OWO) in the treatment of unicompartmental medial osteoarthritis with varus deformity. This study included 79 patients who underwent high tibial osteotomy (HTO) between 2002 and 2008. Pre- and postoperative radiography and computed tomography were used to evaluate the posterior tibial slope, the patellar height, the tibiofemoral angle, and the lateral and medial tibiofemoral joint space. Read More

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http://dx.doi.org/10.1055/s-0038-1668124DOI Listing
August 2018
2 Reads

The learning curve associated with robotic-arm assisted unicompartmental knee arthroplasty.

Bone Joint J 2018 08;100-B(8):1033-1042

University College London Hospitals, The Princess Grace Hospital, and The NIHR Biomedical Research Centre at UCLH, London, UK.

Aims: The primary aim of this study was to determine the surgical team's learning curve for introducing robotic-arm assisted unicompartmental knee arthroplasty (UKA) into routine surgical practice. The secondary objective was to compare accuracy of implant positioning in conventional jig-based UKA versus robotic-arm assisted UKA.

Patients And Methods: This prospective single-surgeon cohort study included 60 consecutive conventional jig-based UKAs compared with 60 consecutive robotic-arm assisted UKAs for medial compartment knee osteoarthritis. Read More

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http://dx.doi.org/10.1302/0301-620X.100B8.BJJ-2018-0040.R1DOI Listing
August 2018
6 Reads

Mitochondrial DNA haplogroups associated with MRI-detected structural damage in early knee osteoarthritis.

Osteoarthritis Cartilage 2018 Nov 20;26(11):1562-1569. Epub 2018 Jul 20.

The University of Arizona Arthritis Center, Tucson, AZ, USA; Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, USA. Electronic address:

Objective: Magnetic resonance imaging (MRI)-detected structural features are associated with increased risk of radiographic osteoarthritis (ROA). Specific mitochondrial DNA (mtDNA) haplogroups have been associated with incident ROA. Our objective was to compare the presence of MRI-detected structural features across mtDNA haplogroups among knees that developed incident ROA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10634584183136
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http://dx.doi.org/10.1016/j.joca.2018.06.016DOI Listing
November 2018
10 Reads

Fixed-bearing unicompartmental knee arthroplasty tolerates higher variance in tibial implant rotation than mobile-bearing designs.

Arch Orthop Trauma Surg 2018 Oct 19;138(10):1463-1469. Epub 2018 Jul 19.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Yildirim Beyazit University, Bilkent, Ankara, Turkey.

Background: UKA necessitates a learning period. From this point of view, it would be logical to prefer the design that tolerates suboptimal tibial rotations better, especially for inexperienced surgeons. The aim of this study was to evaluate and compare the clinical and radiological results of mobile-bearing and fix-bearing UKA designs in case of suboptimal tibial rotations. Read More

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http://dx.doi.org/10.1007/s00402-018-3005-yDOI Listing
October 2018
4 Reads

Acute effects of different orthotic interventions on knee loading parameters in knee osteoarthritis patients with varus malalignment.

Knee 2018 Oct 17;25(5):825-833. Epub 2018 Jul 17.

Funktionsbereich Bewegungsanalytik, IEMM, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, Gebäude D3, 48129 Münster, Germany.

Background: Knee osteoarthritis (KOA) is the most common form of arthritis with an estimated lifetime prevalence of 45%. The use of orthotic devices is a generally accepted conservative therapy in KOA. A new conservative treatment is an ankle-foot orthosis (AFO); however, studies on the biomechanical effects are limited. Read More

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http://dx.doi.org/10.1016/j.knee.2018.06.017DOI Listing
October 2018
19 Reads

High in vivo levels of adipsin lead to increased knee tissue degradation in osteoarthritis: data from humans and animal models.

Rheumatology (Oxford) 2018 10;57(10):1851-1860

Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Canada.

Objective: This study explored the role of the adipokine adipsin in OA.

Methods: Control and OA articular tissues, cells and serum were obtained from human individuals. Serum adipsin levels of human OA individuals were compared with cartilage volume loss as assessed by MRI at 48 months. Read More

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http://dx.doi.org/10.1093/rheumatology/key181DOI Listing
October 2018
1 Read

Can osteoarthritic patients with mild varus deformity be indicated for high tibial osteotomy?

Knee 2018 Oct 20;25(5):856-865. Epub 2018 Jun 20.

Department of Orthopaedic Surgery, Gachon University Gil Medical Center, Gachon University College of Medicine, 21, Namdong-daero 774 beon-gil, Namdong-gu, Incheon, Republic of Korea. Electronic address:

Background: Whether osteoarthritic patients with mild varus deformity can be indicated for high tibial osteotomy (HTO) is not established. We examined the preoperative characteristics and postoperative outcomes of HTO in patients with mild genu varum compared to patients with greater varus deformity.

Methods: Seventy-one patients who underwent HTO were included in this retrospective study. Read More

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http://dx.doi.org/10.1016/j.knee.2018.05.001DOI Listing
October 2018
7 Reads

A Hydrogel Meniscal Replacement: Knee Joint Pressure and Distribution in an Ovine Model Compared to Native Tissue.

Ann Biomed Eng 2018 Nov 19;46(11):1785-1796. Epub 2018 Jun 19.

School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.

Pressure distribution of the native ovine knee meniscus was compared to a medial meniscectomy and three treatment conditions including a suture reattachment of the native tissue, an allograft, and a novel thermoplastic elastomer hydrogel (TPE) construct. The objective of this study was to assess the efficacy of a novel TPE hydrogel construct at restoring joint pressure and distribution. Limbs were loaded in uniaxial compression at 45°, 60°, and 75° flexion and from 0 to 181 kg. Read More

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http://dx.doi.org/10.1007/s10439-018-2069-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279475PMC
November 2018
3 Reads

Suture Anchor Refixation of Meniscal Root Tears Without an Additional Portal.

Arthrosc Tech 2018 May 16;7(5):e511-e515. Epub 2018 Apr 16.

Sportsclinic Cologne, University of Witten/Herdecke, Cologne-Merheim-Medical-Centre, Cologne, Germany.

The biomechanical consequences of a tear of the posterior root of the medial meniscus are comparable to that of a complete meniscectomy. The integrity of the meniscal roots is crucial to enable the important function of load sharing and shock absorption. An untreated root tear leads to extrusion and loss of function of the meniscus causing early degenerative arthritis of the respective knee compartment. Read More

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http://dx.doi.org/10.1016/j.eats.2018.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984481PMC
May 2018
4 Reads

Knotless Medial Meniscus Posterior Root Repair.

Arthrosc Tech 2018 May 2;7(5):e429-e435. Epub 2018 Apr 2.

Orthopaedic Specialty Clinic, Pune, India.

Medial meniscus posterior root tears are common injuries, especially in the Asian world. This injury must be repaired where indicated to restore knee biomechanics and prevent arthritis. Suturing the meniscus using suture tapes provides good hold of the tissue. Read More

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http://dx.doi.org/10.1016/j.eats.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984279PMC
May 2018
4 Reads

[Cartilage/chondrocyte research and osteoarthritis. Recent Topics of surgical treatment for knee osteoarthritis.]

Authors:
Hiroshi Inui

Clin Calcium 2018;28(6):832-839

Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Japan.

Unicompartmental knee arthroplasty(UKA)has been performed for the treatment of isolated unicompartmental knee disease. Satisfactory results have been achieved when used in the medial compartment and strict inclusion criteria are followed. UKA is one of the minimally invasive surgeries and suitable for elderly severe knee osteoarthritis(OA)patients with a lot of complication. Read More

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http://dx.doi.org/CliCa1806832839DOI Listing
January 2018
2 Reads

Mechanism and influencing factors of proximal fibular osteotomy for treatment of medial compartment knee osteoarthritis: A prospective study.

J Int Med Res 2018 Aug 30;46(8):3114-3123. Epub 2018 May 30.

1 Department of Orthopedic Surgery, The Third Hospital of Hebei Medical University (Hebei Orthopedic Hospital), Shijiazhuang, Hebei, P.R. China.

Objectives This study was performed to explore the mechanism of proximal fibular osteotomy (PFO) for treatment of medial compartment knee osteoarthritis (OA) and evaluate the relevant factors influencing the treatment outcome. Methods Fifty-two patients with medial compartment knee OA with varus deformities were prospectively selected. Radiographs were obtained preoperatively and postoperatively. Read More

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http://dx.doi.org/10.1177/0300060518772715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134672PMC
August 2018
24 Reads

[Application of improved precision alignment method of lower limbs mechanical alignment on open wedge high tibial osteotomy].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Jun;31(6):659-664

Knee Ward of Joint Surgery Department, Honghui Hospital, Xi'an Jiao Tong University, Xi'an Shaanxi, 710054, P.R.China.

Objective: To evaluate the effects of the improved precision alignment method of lower limbs mecha-nical alignment for osteoarthritis of the knee in open wedge high tibial osteotomy (OWHTO).

Methods: A retrospective analysis was made on the clinical data of 62 patients (68 knees) with knee osteoarthritis in the medial compartment treated with OWHTO between January 2012 and December 2015 who accorded with the inclusion criteria. The traditional method for positioning lower limb mechanical force line was used in 29 cases (32 knees) (traditional group), and improved method for positioning lower limb mechanical force line in 33 cases (36 knees) (modified group). Read More

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http://dx.doi.org/10.7507/1002-1892.201701037DOI Listing
June 2017
2 Reads

[Change of inflammatory cytokines levels in both synovial fluid and plasm of patients with primary knee medical osteoarthritis after high tibial osteotomy].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Apr;31(4):422-426

Department of Orthopaedics, People's Hospital of Xianxian, Xianxian Hebei, 062250, P.R.China.

Objective: To investigate interleukin-1β (IL-1β), IL-6, and IL-17 levels in both synovial fluid and serum of patients with primary knee medial osteoarthritis (OA) after high tbial osteotomy (HTO).

Methods: Twenty-six patients with primary knee medial OA undergoing HTO between January 2011 and June 2014 (experimental group) and 30 healthy individuals (control group) were recruited into the study. There was no significant difference in gender, age, and body mass index between 2 groups ( >0. Read More

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http://dx.doi.org/10.7507/1002-1892.201609123DOI Listing

Proximal fibular osteotomy to treat medial compartment knee osteoarthritis: Preoperational factors for short-term prognosis.

PLoS One 2018 24;13(5):e0197980. Epub 2018 May 24.

Department of Orthopaedic Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.

Objective: The purpose of this study was to determine the association between preoperational factors and patients' short-term outcome after proximal fibular osteotomy (PFO) and to provide a basis for detailed surgical indication and patient selection.

Methods: This was a retrospective study of patients undergoing PFO between January 2015 and December 2015. Preoperational clinical data including gender, age, duration of disease, visual analogue score (VAS) and American Knee Society (KSS) score were collected. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197980PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967722PMC
December 2018
6 Reads
3.230 Impact Factor

Meniscal pathologies on MRI correlate with increased bone tracer uptake in SPECT/CT.

Eur Radiol 2018 Nov 22;28(11):4696-4704. Epub 2018 May 22.

Department of Radiology and Nuclear Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.

Objectives: To assess the relationship of subchondral bone tracer uptake (BTU) on SPECT/CT and meniscal pathologies on MRI in patients with painful knees.

Methods: Twenty-five patients who had MRI and SPECT/CT within 3 months without knee surgery or grade ≥3 cartilage lesions were prospectively included. Maximum values of each subchondral femorotibial area were quantified and a ratio was calculated in relation to a femoral shaft reference region, which represented the BTU background activity. Read More

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http://dx.doi.org/10.1007/s00330-018-5466-3DOI Listing
November 2018
2 Reads
4.014 Impact Factor

Factors affecting femoral rotational angle based on the posterior condylar axis in gap-based navigation-assisted total knee arthroplasty for valgus knee.

PLoS One 2018 15;13(5):e0197335. Epub 2018 May 15.

Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Background: Achieving proper rotational alignment of the femoral component in total knee arthroplasty (TKA) for valgus knee is challenging because of lateral condylar hypoplasia and lateral cartilage erosion. Gap-based navigation-assisted TKA enables surgeons to determine the angle of femoral component rotation (FCR) based on the posterior condylar axis. This study evaluated the possible factors that affect the rotational alignment of the femoral component based on the posterior condylar axis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197335PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953479PMC
November 2018
1 Read

Inverted Rearfoot posture in subjects with coexisting patellofemoral osteoarthritis in medial knee osteoarthritis: an exploratory study.

J Foot Ankle Res 2018 8;11:17. Epub 2018 May 8.

7Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Background: While abnormal rearfoot posture and its relationship to patellofemoral (PF) pain has been thoroughly discussed in the literature, its relationship to patellofemoral osteoarthritis (PFOA) has not been determined. This study aimed to examine whether rearfoot posture is associated with a higher prevalence of radiographic PFOA in a compartment-specific manner in patients with medial tibiofemoral osteoarthritis (TFOA).

Methods: Participants from orthopedic clinics ( = 68, age 56-90 years, 75. Read More

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http://dx.doi.org/10.1186/s13047-018-0261-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941454PMC
October 2018
2 Reads

The largest survivorship and clinical outcomes study of the fixed bearing Stryker Triathlon Partial Knee Replacement - A multi-surgeon, single centre cohort study with a minimum of two years of follow-up.

Knee 2018 Aug 3;25(4):732-736. Epub 2018 May 3.

Exeter Knee Reconstruction Unit (EKRU), Royal Devon and Exeter Hospital, Barrack Road, Exeter, Devon, United Kingdom.

Background: The surgical management of isolated medial compartment degenerative disease of the knee causes debate. Unicompartmental arthroplasty options include fixed and mobile bearing implant designs with fixed bearing becoming increasingly popular. We present the largest cohort of a fixed bearing single radius design, Stryker Triathlon Partial Knee Replacement (PKR). Read More

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http://dx.doi.org/10.1016/j.knee.2018.04.002DOI Listing
August 2018
4 Reads

Medial Compartment Decompression by Proximal Fibular Osteotomy: A Biomechanical Cadaver Study.

Orthopedics 2018 Jul 30;41(4):e496-e501. Epub 2018 Apr 30.

Medial compartment knee osteoarthritis is a painful and debilitating disease. A proximal fibular osteotomy is a novel, simple surgical technique that may reduce pain and improve function for patients with osteoarthritis. The purpose of this biomechanical cadaver study was to determine what effect proximal fibular osteotomy had on knee joint and ankle pressures and tibia strain. Read More

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http://dx.doi.org/10.3928/01477447-20180424-05DOI Listing
July 2018
2 Reads

Local associations between knee cartilage T and T relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis.

Knee 2018 Jun 19;25(3):406-416. Epub 2018 Apr 19.

Musculoskeletal Quantitative Imaging Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, San Francisco, CA, USA; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, 1500 Owens Street, San Francisco, CA, USA.

Background: This study aimed to utilize voxel-based relaxometry (VBR) to examine local correlations between patellofemoral joint (PFJ) stress during gait and PFJ cartilage relaxation times.

Methods: Eighty-three subjects with and without PFJ osteoarthritis (OA) underwent knee magnetic resonance (MR) images using fast spin-echo, T1ρ and T2 relaxation time sequences. Patellar and trochlear cartilage relaxation times were computed for each voxel. Read More

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http://dx.doi.org/10.1016/j.knee.2018.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049815PMC
June 2018
3 Reads

Distal Femoral Varus Osteotomy for the Management of Valgus Deformity of the Knee.

J Am Acad Orthop Surg 2018 May;26(9):313-324

From the Department of Orthopaedic Surgery, University of Missouri, Columbia, MO (Dr. Sherman), the Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City, OK (Dr. Thompson), and the Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO (Dr. Clohisy).

Distal femoral varus osteotomy is a well-described treatment option for patients with valgus malalignment associated with a variety of underlying conditions. This procedure may be the definitive treatment option in active patients with isolated lateral compartment osteoarthritis or posttraumatic arthritis. It may be a useful concomitant procedure in young patients with lateral meniscus deficiency, focal chondral defects, chronic medial collateral ligament insufficiency, and/or patellofemoral instability. Read More

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http://dx.doi.org/10.5435/JAAOS-D-16-00179DOI Listing
May 2018
9 Reads

Decreased Time to Return to Work Using Robotic-Assisted Unicompartmental Knee Arthroplasty Compared to Conventional Techniques.

Surg Technol Int 2018 06;32:279-283

Department of Orthopaedic Surgery, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina.

Introduction: Unicompartmental knee arthroplasty (UKA) is a commonly used procedure for patients suffering from debilitating unicompartmental knee arthritis. For UKA recipients, robotic-assisted surgery has served as an aid in improving surgical accuracy and precision. While studies exist detailing outcomes of robotic UKA, to our knowledge, there are no studies assessing time to return to work using robotic-assisted UKA. Read More

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June 2018
5 Reads

The association between the Mediterranean diet and magnetic resonance parameters for knee osteoarthritis: data from the Osteoarthritis Initiative.

Clin Rheumatol 2018 Aug 3;37(8):2187-2193. Epub 2018 Apr 3.

Department of Radiology, University of Foggia, Foggia, Italy.

The Mediterranean diet appears to be beneficial for osteoarthritis (OA), but the few data available regarding the association between the diet and the condition are limited to X-ray and clinical findings. The current study aimed to investigate the association between adherence to the Mediterranean diet and knee cartilage morphology, assessed using magnetic resonance (MRI) in a cohort of North American participants. Seven hundred eighty-three participants in the Osteoarthritis Initiative (59. Read More

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http://dx.doi.org/10.1007/s10067-018-4075-5DOI Listing
August 2018
2 Reads