4,353 results match your criteria Maturitas[Journal]


Menopause: Women should not suffer in silence.

Maturitas 2019 Jan 30. Epub 2019 Jan 30.

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma, 67, 56126, Pisa, Italy.

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http://dx.doi.org/10.1016/j.maturitas.2019.01.014DOI Listing
January 2019
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Associations of postmenopausal hormone therapy with metabolic syndrome among diabetic and non-diabetic women.

Maturitas 2019 Mar 20;121:76-82. Epub 2018 Dec 20.

Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Republic of Korea; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea. Electronic address:

A lack of estrogen due to menopause changes metabolic homeostasis, which increases the risk of metabolic syndrome (MetS) in postmenopausal women. Hormone therapy (HT) has beneficial effects on chronic diseases as well as on menopause symptoms. The aim of this study was to investigate the association of HT use with MetS and its components by diabetes status in middle-aged postmenopausal Korean women. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.012DOI Listing

Priming of grasping muscles when viewing a safety handle is diminished with age.

Maturitas 2019 Mar 5;121:7-12. Epub 2018 Dec 5.

Department of Kinesiology & Health Science, Utah State University, United States.

Merely viewing objects within reachable space can activate motor cortical networks and potentiate movement. This holds potential value for smooth interaction with objects in our surroundings, and could offer an advantage for quickly generating targeted hand movements (e.g. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.005DOI Listing

The experience of intimate partner violence among older women: A narrative review.

Maturitas 2019 Mar 18;121:63-75. Epub 2018 Dec 18.

UCL Institute for Global Health, Mortimer Market Centre, Off Capper Street, London, WC1E 6JB, UK. Electronic address:

Intimate partner violence (IPV) against women is a significant public health issue globally. It has serious physical and psychological health consequences as well huge economic and social costs. With an ageing population globally, it is important to understand how older women experience IPV. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.011DOI Listing

High parathyroid hormone levels are associated with poor balance in older persons: A cross-sectional study.

Maturitas 2019 Mar 20;121:57-62. Epub 2018 Dec 20.

Department of Medicine - Western Health, Melbourne Medical School, The University of Melbourne, St. Albans, Victoria, Australia; Australian Institute for Musculoskeletal Science (AIMSS), The University of Melbourne and Western Health, St. Albans, Victoria, Australia. Electronic address:

Objectives: A high level of parathyroid hormone (PTH) was recently identified as a risk factor for falling. As balance instability is one of the major risk factors for falls, we aimed to investigate whether high PTH concentrations are associated with poor balance in older persons.

Study Design: Cross-sectional study with 127 community-dwelling older adults (75% female), aged 65-96 years, at the Falls and Fracture Clinic, Western Health-Sunshine Hospital, Melbourne, Australia. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.013DOI Listing

Cognitive frailty: A conceptual systematic review and an operational proposal for future research.

Maturitas 2019 Mar 7;121:48-56. Epub 2018 Dec 7.

Universidade da Coruña, Gerontology Research Group, Instituto de Investigación biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, A Coruña, Spain.

Objective: To analyze the definition of "cognitive frailty" and to study the conceptual and operational definitions used and their implications for empirical research. The relationships between this concept and cognitive reserve, the role of neuropathology and brain reserve, motor signs of aging and the reversibility of cognitive frailty are also discussed.

Study Design: Systematic review of empirical studies identified from Medline Advanced 1966, CINAHL, Web of Science, PsycINFO, and Scopus until August 2017. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.006DOI Listing
March 2019
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The association of urinary estrogen levels with urinary isoflavone levels: Difference between premenopausal women and postmenopausal women.

Maturitas 2019 Mar 20;121:41-47. Epub 2018 Dec 20.

Graduate School of Health Sciences, Gunma University, Maebashi, Japan.

Results of studies on the associations of soy food intake with urinary estrogen levels in premenopausal women and in postmenopausal women have been inconsistent. We examined the associations of urinary isoflavone levels as well as soy food intake with estrone (E1) and estradiol (E2) in pre- and postmenopausal women. In addition, we compared the levels of isoflavones, E1 and E2 across current hormone users such as those receiving hormone replacement therapy and those using oral contraceptives and non-users among both pre- and postmenopausal women. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.010DOI Listing
March 2019
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Adverse effect of self-reported hearing disability in elderly Italians: Results from the InveCe.Ab study.

Maturitas 2019 Mar 12;121:35-40. Epub 2018 Dec 12.

Golgi Cenci Foundation, Corso San Martino 10, 20081, Abbiategrasso, Italy. Electronic address:

Objective: Hearing loss is a common chronic condition in elderly people. The prevalence of disabling hearing loss among the elderly worldwide is 33% and in Italy ranges from 0.6% (profound hearing loss) to 39% (mild hearing loss). Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.009DOI Listing
March 2019
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Gait speed assessed by a 4-m walk test is not representative of daily-life gait speed in community-dwelling adults.

Maturitas 2019 Mar 7;121:28-34. Epub 2018 Dec 7.

Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, the Netherlands. Electronic address:

Objectives: Standardized tests of gait speed are regarded as being of clinical value, but they are typically performed under optimal conditions, and may not reflect daily-life gait behavior. The aim of this study was to compare 4-m gait speed to the distribution of daily-life gait speed.

Study Design: The cross-sectional Grey Power cohort included 254 community-dwelling participants aged 18 years or more. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.008DOI Listing

Association between premature ovarian insufficiency, early menopause, socioeconomic status in a nationally representative sample from Korea.

Maturitas 2019 Mar 5;121:22-27. Epub 2018 Dec 5.

Department of Occupational and Environmental Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address:

Objective: We investigated whether, in the Korean population, the risk of premature ovarian insufficiency (POI) and early menopause varies with a woman's socioeconomic status, evaluated in relation to income, education, and occupation.

Methods: This cross-sectional, population-based study involved 31,508 women aged >19 years registered in the Korea National Health and Nutrition Examination Survey (KNHANES) (2007-2016). Menopausal status and socioeconomic status were obtained from self-reported KNHANES data. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.004DOI Listing
March 2019
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Methamphetamine and its immune-modulating effects.

Maturitas 2019 Mar 5;121:13-21. Epub 2018 Dec 5.

Institute for Health and Sport, Victoria University, Melbourne, VIC, Australia. Electronic address:

The recreational use of methamphetamine (METH, or ice) is a global burden. It pervades and plagues contemporary society; it has been estimated that there are up to 35 million users worldwide. METH is a highly addictive psychotropic compound which acts on the central nervous system, and chronic use can induce psychotic behavior. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.003DOI Listing
March 2019
2 Reads
2.942 Impact Factor

Insulin resistance and adrenal incidentalomas: A bidirectional relationship.

Maturitas 2019 Mar 5;121:1-6. Epub 2018 Dec 5.

School of Medicine, European University Cyprus, Nicosia, Cyprus; Division of Endocrinology and Diabetes, "Aghia Sophia" Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In this review, we aimed to investigate the possible reasons behind the increased frequency in AI detection, especially in ageing populations. The pathophysiological effects of insulin resistance (IR), hyperinsulinemia and various anabolic pathways are analyzed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183067
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http://dx.doi.org/10.1016/j.maturitas.2018.12.002DOI Listing
March 2019
3 Reads

A scoping review of behaviour change theories in adults without dementia to adapt and develop the 'PHYT in dementia', a model promoting physical activity in people with dementia.

Maturitas 2019 Mar 23;121:101-113. Epub 2019 Jan 23.

Division of Rehabilitation and Ageing, School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.

Introduction: Research has established that exercise and physical activity can improve executive functioning, independence and quality of life in people with dementia. A dedicated theory explaining behaviour change in relation to physical activity in people with dementia does not exist. We aimed to develop a theoretical model which can be used to inform effective interventions to promote physical activity in people with dementia. Read More

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http://dx.doi.org/10.1016/j.maturitas.2019.01.008DOI Listing
March 2019
4 Reads

Spreading the word: Evidently Cochrane.

Maturitas 2018 Dec 23. Epub 2018 Dec 23.

Cochrane UK, United Kingdom.

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http://dx.doi.org/10.1016/j.maturitas.2018.12.014DOI Listing
December 2018

Development and evaluation of online menopause awareness training for line managers in UK organizations.

Maturitas 2019 Feb 4;120:83-89. Epub 2018 Dec 4.

Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. Electronic address:

Objectives: To develop and evaluate a 30-min online training for managers, in order to improve menopause-related knowledge, attitudes and confidence in having supportive discussions with women experiencing menopausal symptoms at work. The study also explored intentions and behaviour in terms of having conversations.

Study Design: A prospective, pre-post design involved collecting data at three time points: pre-training, immediately after training, and four weeks post-training. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.001DOI Listing
February 2019

Association between tissue inhibitor of metalloproteinase (TIMP) genetic polymorphisms and primary ovarian insufficiency (POI).

Maturitas 2019 Feb 27;120:77-82. Epub 2018 Nov 27.

Department of Biomedical Science, College of Life Science, CHA University, Seongnam 13488, South Korea; Institute for Clinical Research, CHA Bundang Medical Center, CHA University, Seongnam 13496, South Korea. Electronic address:

Background: Until now, an association between tissue inhibitor of metalloproteinase (TIMP) polymorphisms and primary ovarian insufficiency (POI) has not been identified. The aim of our study was to investigate whether the TIMP polymorphisms TIMP1T > C (rs4898), TIMP1G > A (rs6609533), TIMP2G > C (rs8179090), TIMP2G > A (rs2277698), TIMP3G > A (rs135029), and TIMP4T > C (rs3755724), which regulate matrix metalloproteinases (MMPs), confer a risk for primary ovarian insufficiency (POI) in Korean women (further studies would be required to evaluate the associations between TIMP polymorphisms and POI in other populations).

Methods: We genotyped 137 POI patients and 236 controls for the single nucleotide polymorphism sites using PCR-RFLP analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183046
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http://dx.doi.org/10.1016/j.maturitas.2018.11.018DOI Listing
February 2019
7 Reads

A 12-year retrospective analysis of differences between elderly and oldest old patients referred to the emergency department of a large tertiary hospital.

Maturitas 2019 Feb 19;120:7-11. Epub 2018 Nov 19.

Emergency Department, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy. Electronic address:

Objectives: Globally, the average age of the population is increasing. Patients aged >65 years attending hospital emergency departments (EDs) differ from younger patients; in particular, they often present with multiple comorbidities. Our retrospective study evaluates the number of attendances at our ED by elderly patients in the 12 years from January 2005 to December 2017. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.011DOI Listing
February 2019
2 Reads
2.942 Impact Factor

Determinants of hormone therapy uptake and decision-making after bilateral oophorectomy (BO): A narrative review.

Maturitas 2019 Feb 12;120:68-76. Epub 2018 Nov 12.

Faculty of Pharmacy and Pharmaceutical Sciences, 3-171 Edmonton Clinic Health Academy (ECHA), University of Alberta, Edmonton, AB, T6G 1C9, Canada. Electronic address:

Objective Early surgical menopause (≤45 years) can have significant short- and long-term health consequences. Hormone therapy (HT) is recommended for women with no contraindications. However, HT is greatly underutilized among these women due to their fear of the associated risks. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.005DOI Listing
February 2019
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Association of moderate/severe vertebral fractures with reduced trabecular volumetric bone density in older women and reduced areal femoral neck bone density in older men from the community: A cross-sectional study (SPAH).

Maturitas 2019 Feb 27;120:61-67. Epub 2018 Nov 27.

Bone Metabolism Laboratory, Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. Electronic address:

Background: Many vertebral fractures (VF) occur in individuals classified by DXA as being at low risk of fragility fractures. The aim of this study was to verify the association between VF and peripheral bone microarchitecture and strength parameters (SP) using, in addition to DXA, high-resolution peripheral quantitative computed tomography (HR-pQCT) and axial bone microarchitecture using the trabecular bone score (TBS).

Study Design: Cross-sectional study of 276 community-dwelling subjects aged ≥65 years from the SPAH study cohort. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.019DOI Listing
February 2019
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Association of sedentary time and physical fitness with ideal cardiovascular health in perimenopausal women: The FLAMENCO project.

Maturitas 2019 Feb 23;120:53-60. Epub 2018 Nov 23.

Department of Physiology, Faculty of Pharmacy and Institute of Nutrition and Food Technology, University of Granada, Granada, Spain.

Introduction: Healthier lifestyle behaviours might be related to a lower cardiometabolic risk predisposed by menopause transition. The objectives of the study were: 1) to examine the association of sedentary time (ST) and physical fitness with "Ideal Cardiovascular Health" (ICH) in perimenopausal women, and 2) to determine the capacity of ST and physical fitness tests to discriminate between the presence or absence of ICH status in this population.

Study Design: Observational cross-sectional study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183056
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http://dx.doi.org/10.1016/j.maturitas.2018.11.015DOI Listing
February 2019
8 Reads

Antihistamine use and risk of ovarian cancer: A population-based case-control study.

Maturitas 2019 Feb 23;120:47-52. Epub 2018 Nov 23.

Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Objective: Histamine is suggested to play a role in ovarian carcinogenesis. We examined the association between antihistamine use and ovarian cancer risk in a nationwide case-control study.

Study Design: Cases (n = 5 556) comprised all women in Denmark aged 30-84 years with a histologically verified first diagnosis of epithelial ovarian cancer during 2000-2015. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183057
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http://dx.doi.org/10.1016/j.maturitas.2018.11.014DOI Listing
February 2019
8 Reads

Use of a robotic walking aid in rehabilitation to reduce fear of falling is feasible and acceptable from the end user's perspective: A randomised comparative study.

Maturitas 2019 Feb 17;120:40-46. Epub 2018 Nov 17.

Gérontopôle, University Hospital of Toulouse, UPS, F-31400 Toulouse, France; Unité 1027, INSERM,31059, Toulouse, France. Electronic address:

Objectives To determine the acceptability and feasibility of the use of a robotic walking aid to support the work of physiotherapists in reducing fear of falling in the rehabilitation of elderly patients with 'psychomotor disadaptation' (the most severe form of post-fall syndrome). Study design 20 participants with psychomotor disadaptation admitted to an academic rehabilitation ward were randomised to receive physiotherapist care supported by the SafeWalker® robotic walking aid or standard care only, for ten days. SafeWalker® supports the body weight whilst securing postural stability without relying on upper body strength or high cognitive demand. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.008DOI Listing
February 2019
12 Reads

A comparison of quality of life and resilience in menopausal women with and without a history of gynaecological cancer.

Maturitas 2019 Feb 17;120:35-39. Epub 2018 Nov 17.

Women's Health Institute of the Hospital Clínico San Carlos, Madrid, Spain.

Background And Objectives: Resilience is a dynamic process that implies positive adaptation to adversity, and it is tested in stressful situations. In this study we compared resilience and menopause-related quality of life in women with and without a history of gynaecological cancer.

Methods: A cross-sectional study was conducted with a total of 293 participants, all of them menopausal women: 80 cancer survivors and 213 without a history of cancer. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.012DOI Listing
February 2019

Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS).

Maturitas 2019 Feb 19;120:29-34. Epub 2018 Nov 19.

Department of Clinical Science, University of Bergen, Jonas Lies veg 87, 5021 Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Jonas Lies veg 65, 5021 Bergen, Norway.

Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The effects of HRT on lung function decline, hence lung ageing, have not yet been investigated despite the recognized effects of HRT on other health outcomes. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.007DOI Listing
February 2019
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Improvement of menopausal symptoms and the impact on work ability: A retrospective cohort pilot study.

Maturitas 2019 Feb 5;120:23-28. Epub 2018 Nov 5.

Department of Obstetrics and Gynaecology, Nij Smellinghe Hospital, Post box 20200, 9200 DA Drachten, the Netherlands. Electronic address:

Objective: In this study we aimed to pilot test the hypothesis that in women who are severely bothered by their menopausal complaints, improvement of menopausal symptoms is associated with an improvement in self-perceived work ability.

Study Design: This retrospective cohort study assessed the work ability of first-time attendees (n = 31) of a menopause clinic at baseline (T0) and 3-9 months follow-up (T1). All patients received care as usual according to local protocol, no interventions were applied by the researchers. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.015DOI Listing
February 2019

The social construction of dementia: Systematic review and metacognitive model of enculturation.

Maturitas 2019 Feb 17;120:12-22. Epub 2018 Nov 17.

Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

Background: The stigma associated with dementia may be influenced by how the condition has been socially constructed throughout history.

Objectives: To conduct a systematic review tracing the historical representations of dementia, from the perspectives of cultural transmission theory and social constructivism.

Methods: A systematic search was run on five electronic databases: Wellcome Library, PsycINFO, CINAHL, IBSS, and EMBASE. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.009DOI Listing
February 2019
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New therapeutic targets for osteoporosis.

Maturitas 2019 Feb 16;120:1-6. Epub 2018 Nov 16.

Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece; Centre of Orthopaedic and Regenerative Medicine Research (CORE), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki, Thessaloniki, Greece.

New anti-osteoporotic agents have been developed, potentially enriching the therapeutic armamentarium. Currently available osteoanabolic therapies are the parathyroid hormone (PTH) and PTH-related peptide (PTHrP) synthetic analogues, teriparatide and abaloparatide. Daily administration at doses of 20 and 80 μg, respectively, in contrast to continuous PTH secretion, leads to increased bone formation and reduces vertebral and non-vertebral fracture risk. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183073
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http://dx.doi.org/10.1016/j.maturitas.2018.11.010DOI Listing
February 2019
2 Reads

Austerity, socioeconomic inequalities and stalling life expectancy in the UK: Two parallel stories or one?

Maturitas 2018 Dec 6. Epub 2018 Dec 6.

Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.maturitas.2018.12.007DOI Listing
December 2018

Food insecurity increases the risk of malnutrition among community-dwelling older adults.

Maturitas 2019 Jan 28;119:8-13. Epub 2018 Oct 28.

Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Objectives: To assess the prevalence of malnutrition and food insecurity (uncertainty, or limited ability to acquire acceptable foods through socially acceptable ways), among non-hospitalised, non-institutionalised, community-dwelling older adults, and to identify possible dietary, socioeconomic and health factors associated with them.

Study Design: Cross-sectional, with 207 older adult participants inhabitants of Thessaloniki and Kavala, Greece. A medical diagnosis was not a criterion for exclusion from participation. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.009DOI Listing
January 2019

The health economics burden of sarcopenia: a systematic review.

Maturitas 2019 Jan 12;119:61-69. Epub 2018 Nov 12.

World Health Organization Collaborating Center for the Public Health Aspects of Musculoskeletal Health and Aging, Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.

Despite of better knowledge about sarcopenia, an optimal understanding of its consequences from a public health perspective remains a challenge. Specifically, the economic burden of the illness is unclear. As a support for the public health policy makers and other health actors, our objective was to perform a systematic review of the literature comparing healthcare costs between sarcopenic and non-sarcopenic patients (under the registration number CRD42018099291). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183069
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http://dx.doi.org/10.1016/j.maturitas.2018.11.003DOI Listing
January 2019
8 Reads

Changes in frailty status in a community-dwelling cohort of older adults: The VERISAÚDE study.

Maturitas 2019 Jan 15;119:54-60. Epub 2018 Nov 15.

Universidade da Coruña, Gerontology Research Group, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, 15071 A Coruña, Spain. Electronic address:

Objectives: Greater understanding of changes in the degree of frailty is important for clarifying the natural history of frailty and may help clinical decision-making regarding preventive interventions. The objectives of this study were to explore natural frailty transition rates at 1-year follow-up and to identify the main determinants of such transitions.

Study Design: Prospective longitudinal study covering a representative sample of community-dwelling older adults aged ≥65 years (n = 749) at baseline, and transition information at 1-year follow-up (n = 537). Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.006DOI Listing
January 2019
2 Reads

A clinical prescription for heart health in midlife women.

Maturitas 2019 Jan 12;119:46-53. Epub 2018 Nov 12.

Barbra Streisand Women's Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Cardiovascular disease is the leading cause of death in women throughout the United States and Europe. Despite efforts to raise awareness, the sex-specific risk factors are still poorly recognized in both regions, and many women do not identify cardiovascular disease as a primary threat. During midlife, the incidence of cardiovascular disease increases dramatically, and this unique time gives an opportunity to identify both traditional cardiovascular risk factors as well as emerging risk factors unique to women. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290356PMC
January 2019
1 Read

Low bone mineral density is associated with an elevated risk of developing increased arterial stiffness: A 10-year follow-up of Japanese women from the Japanese Population-based Osteoporosis (JPOS) cohort study.

Maturitas 2019 Jan 11;119:39-45. Epub 2018 Nov 11.

Department of Public Health, Kindai University Faculty of Medicine, 377-2 Oonohigashi, Osaka-Sayama, Osaka, 589-8511, Japan. Electronic address:

Objective: Only a few longitudinal studies have assessed the relationship between bone mineral density (BMD) and arteriosclerosis. This study aimed to determine whether low BMD at baseline is associated with the development of increased arterial stiffness, as evaluated by brachial-ankle pulse wave velocity (baPWV), in Japanese women.

Methods: A baPWV value of ≥1800 cm/s was adopted as the criterion for increased arterial stiffness, i. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.001DOI Listing
January 2019
2 Reads

Immunomodulatory effects of probiotics: Can they be used to treat allergies and autoimmune diseases?

Maturitas 2019 Jan 12;119:25-38. Epub 2018 Nov 12.

Institute for Health and Sport, Victoria University, Melbourne, Australia. Electronic address:

As a person ages, physiological, immunological and gut microbiome changes collectively result in an array of chronic conditions. According to the 'hygiene hypothesis' the increasing prevalence of immune-mediated disorders may be related to intestinal dysbiosis, leading to immune dysfunction and associated conditions such as eczema, asthma, allergies and autoimmune diseases. Beneficial probiotic bacteria can be utilized by increasing their abundance within the gastrointestinal lumen, which in turn will modulate immune cells, such as, T helper (Th)-1, Th2, Th17, regulatory T (Treg) cells and B cells, which have direct relevance to human health and the pathogenesis of immune disorders. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.002DOI Listing
January 2019
1 Read
2.942 Impact Factor

Botulinum toxin in women's health: An update.

Maturitas 2019 Jan 22;119:21-24. Epub 2018 Oct 22.

The Royal Women's Hospital, 20 Flemington Road Parkville, Victoria 3052 Australia; The University of Melbourne, Department of Obstetrics and Gynaecology, 7thFloor Royal Women's Hospital, 20 Flemington Road Parkville, Victoria 3052 Australia. Electronic address:

Botulinum toxin, from the bacteria Clostridium botulinum, acts by block the pre-synaptic release of acetylcholine at the neuromuscular junction, resulting in temporary muscle paralysis. There are several clinically available formulations, the most extensively studied being of onabotulinumtoxinA. This article outlines three of the common clinical applications of onabotulinumtoxinA relevant to women's health: the management of symptoms of overactive bladder, chronic migraine and facial lines. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.005DOI Listing
January 2019
2 Reads

Anxiety and risk of dementia: Systematic review and meta-analysis of prospective cohort studies.

Maturitas 2019 Jan 30;119:14-20. Epub 2018 Oct 30.

Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain; Departamento de Psicología y Sociología, Universidad de Zaragoza, C/Doctor Cerrada 1-5, 50009 Zaragoza, Spain. Electronic address:

Objectives: Anxiety is postulated to be modifiable risk factor for dementia. Our primary aim was to conduct a meta-analysis of community-based cohort studies that investigated the association between anxiety and dementia.

Design: We identified relevant, high-quality papers published up to January 2018 by searching PubMed and Web of Science. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.014DOI Listing
January 2019
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Hormone variability and hot flash experience: Results from the midlife women's health study.

Maturitas 2019 Jan 23;119:1-7. Epub 2018 Oct 23.

Department of Pathobiology, University of Illinois College of Veterinary Medicine, 2001 S. Lincoln Ave, Urbana, IL, USA. Electronic address:

Objective: Hot flashes are believed to be related to hormonal changes. However, the relationship between hormonal fluctuations and hot flashes has not been studied. The objective of this study is to determine hormone measurement summaries that best explain the incidence of hot flashes in midlife women. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289582PMC
January 2019
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Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part II: Evaluation of tolerability and safety.

Maturitas 2019 Mar 28;121:93-100. Epub 2018 Nov 28.

Department of Gynecological, Obstetrical and Urological Sciences, 'Sapienza' University of Rome, Rome, Italy.

Objective: To evaluate the tolerability and safety of ospemifene in treating dyspareunia associated with postmenopausal vulvo- vaginal atrophy (VVA).

Methods: The literature was searched through to 31 July 2018 to identify randomized controlled trials comparing ospemifene 60 mg against placebo for the treatment of VVA. Two groups of outcomes were selected: 1) side-effects, including hot flushes, urinary tract infection (UTI), headache, deep venous thrombosis (DVT), coronary heart disease (CHD), cardiovascular event (CVE), discontinuation due to side-effects, serious adverse event (SAE); 2) Safety, in relation to endometrial thickness, vaginal bleeding, breast tenderness, breast and endometrial cancer. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.017DOI Listing
March 2019
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Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part I: Evaluation of efficacy.

Maturitas 2019 Mar 24;121:86-92. Epub 2018 Nov 24.

Department of Gynecological, Obstetrical and Urological Sciences, 'Sapienza' University of Rome, Rome, Italy.

Objective: To evaluate the efficacy of ospemifene in treating dyspareunia associated with postmenopausal vulvo-vaginal atrophy (VVA).

Methods: A structured search was carried out in PubMed-Medlin, Embase, Cochrane Controlled Trials Register databases through to 31 July 2018. The search included the following terms: "Ospemifene", "vulvovaginal atrophy", "dyspareunia", "SERM" and "randomized controlled trial" (RCTs). Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.016DOI Listing
March 2019
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A translational approach for the clinical application of recently updated definitions of malnutrition (GLIM) and sarcopenia (EWGSOP2).

Maturitas 2018 Nov 22. Epub 2018 Nov 22.

Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden; Theme Aging, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.maturitas.2018.11.013DOI Listing
November 2018

Foot problems as a risk factor for falls in community-dwelling older people: A systematic review and meta-analysis.

Maturitas 2018 Dec 2;118:7-14. Epub 2018 Oct 2.

School of Health Sciences, Faculty of Health, University of Newcastle, Ourimbah, New South Wales, 2258, Australia.

Background: Foot problems are common in older people. The objective of this systematic review was to determine whether foot problems increase the risk of falling in community-dwelling older people.

Methods: Electronic databases were searched from inception to May 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183057
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http://dx.doi.org/10.1016/j.maturitas.2018.10.001DOI Listing
December 2018
12 Reads

Gout - An update of aetiology, genetics, co-morbidities and management.

Maturitas 2018 Dec 26;118:67-73. Epub 2018 Oct 26.

University of Queensland School of Clinical Medicine, Royal Brisbane and Women's Hospital, Butterfield Street, Herston, Brisbane, Queensland, 4006, Australia. Electronic address:

Gout is an increasingly common chronic disorder of urate crystal deposition that manifests as flares of acute inflammatory arthritis. Hyperuricaemia is a prerequisite and a fifth of both men and woman are hyperuricaemic. The prevalence of gout is much lower than the prevalence of hyperuricaemia for reasons that are not currently clear. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183053
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http://dx.doi.org/10.1016/j.maturitas.2018.10.012DOI Listing
December 2018
23 Reads

Olive oil consumption and human health: A narrative review.

Maturitas 2018 Dec 26;118:60-66. Epub 2018 Oct 26.

Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece; Faculty of Health, University of Canberra, Australia; School of Allied Health, College of Science, Health and Engineering, LA TROBE University, Australia. Electronic address:

The potential health benefits of olive oil consumption, particularly within the context of the Mediterranean diet, have been extensively investigated. However, its specific health benefits remain to be confirmed. The aim of the present work is to review the scientific evidence regarding the specific impact of olive oil consumption on human health, including the prevention of cardiovascular disease, cancers, and diabetes mellitus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183065
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http://dx.doi.org/10.1016/j.maturitas.2018.10.013DOI Listing
December 2018
6 Reads
2.942 Impact Factor

Medical cannabis use in older patients: Update on medical knowledge.

Authors:
Olivier Beauchet

Maturitas 2018 Dec 25;118:56-59. Epub 2018 Oct 25.

Department of Medicine, Division of Geriatric Medicine, Sir Mortimer B. Davis - Jewish General Hospital and Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada; Dr. Joseph Kaufmann Chair in Geriatric Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Centre of Excellence on Longevity of McGill integrated University Health Network, Quebec, Canada; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. Electronic address:

Background: There is increasing scientific data suggesting that cannabis is beneficial for a large range of medical conditions. Physicians need up-to-date medical knowledge (i.e. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.010DOI Listing
December 2018

Understanding driving anxiety in older adults.

Maturitas 2018 Dec 26;118:51-55. Epub 2018 Oct 26.

Biostatistics Unit, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin 9054, New Zealand. Electronic address:

Background/objectives: Driving anxiety is a heterogeneous experience that can impact on everyday activities. Little is known about whether older adults experience driving anxiety and, if so, what impact it has on their health, functioning, and quality of life. This is particularly important given the ageing population and driving patterns of older drivers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183061
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http://dx.doi.org/10.1016/j.maturitas.2018.10.008DOI Listing
December 2018
6 Reads

Risk of asthma onset after natural and surgical menopause: Results from the French E3N cohort.

Maturitas 2018 Dec 24;118:44-50. Epub 2018 Oct 24.

UMR 1152, Pathophysiology and Epidemiology of Respiratory Diseases, Epidemiology Team, Inserm, Paris, France; UMR 1152, Univ Paris Diderot Paris7, Paris, France. Electronic address:

Background: The gender switch in asthma incidence around puberty has been put forward to suggest a role of sex hormones in asthma. However, there are limited and inconsistent findings on change in asthma incidence with menopause. We aimed to investigate the associations between menopause and asthma incidence, and interactions with overweight/obesity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183032
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http://dx.doi.org/10.1016/j.maturitas.2018.10.006DOI Listing
December 2018
11 Reads

Factors associated with prevalent and incident foot pain: data from the Tasmanian Older Adult Cohort Study.

Maturitas 2018 Dec 21;118:38-43. Epub 2018 Oct 21.

Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia. Electronic address:

Objectives: To describe factors associated with prevalent and incident foot pain in a population-based cohort of older adults (n = 1092).

Study Design: Longitudinal observational study.

Main Outcome Measures: Prevalent foot pain, incident foot pain after 5 years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785122183037
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http://dx.doi.org/10.1016/j.maturitas.2018.10.004DOI Listing
December 2018
8 Reads

Therapeutic options for aromatase inhibitor-associated arthralgia in breast cancer survivors: A systematic review of systematic reviews, evidence mapping, and network meta-analysis.

Maturitas 2018 Dec 30;118:29-37. Epub 2018 Sep 30.

Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seong-Nam, South Korea.

Aromatase inhibitor-associated arthralgia (AIA) is a common problem in breast cancer survivors and is associated with noncompliance with aromatase inhibitor therapy. The aim of this research was to assess the current evidence for the various therapeutic options available for AIA. We searched the PubMed, EMBASE, Cochrane Database of Systematic Reviews, and Database of Abstracts of Reviews of Effects for systematic reviews of trials investigating treatments for AIA to June 2018. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.09.005DOI Listing
December 2018

Feasibility, safety, acceptability, and functional outcomes of playing Nintendo Wii Fit Plus for frail older adults: A randomized feasibility clinical trial.

Maturitas 2018 Dec 4;118:20-28. Epub 2018 Oct 4.

School of Medicine, University of Sao Paulo - Department of Physical Therapy, Speech Therapy and Occupational Therapy, 51 Cipotânea Street, University City, Sao Paulo, SP, Zip Code: 05360-160, Brazil. Electronic address:

Background: Recently, interactive video games (IVGs) have been used as a health-care intervention that provides both exercise and cognitive stimulation. Several studies have shown that IVGs can improve postural control, gait, cognition, and functional independence in elderly people and patients with neurological disease. However, there is a lack of evidence about the effects of IVGs on frail and pre-frail elderly people. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.002DOI Listing
December 2018
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Linking the menopause rating scale to the International classification of functioning, disability and health - A first step towards the implementation of the EMAS menopause health care model.

Maturitas 2018 Dec 5;118:15-19. Epub 2018 Oct 5.

Department of Obstetrics and Gynecology, University of Bern, Switzerland. Electronic address:

Objectives: To link the Menopause Rating Scale (MRS-II) to the International Classification of Functioning, Disability and Health (ICF) and present a clinical application of an ICF-based tool.

Study Design: The MRS-II was linked to the corresponding ICF category. The linked items were used to generate an ICF Categorical Profile. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.10.003DOI Listing
December 2018