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Cureus 2019 Feb 6;11(2):e4023. Epub 2019 Feb 6.

Internal Medicine, University of Connecticut, Farmington, USA.

Cerebral sinus venous thrombosis (CSVT) is a rare complication of acute mastoiditis with a declining incidence in the post-antibiotic era. In the adult population its incidence ranges from three to four cases per million. Here we present a case of a 47-year-old female with triple negative breast cancer on chemotherapy who underwent a molar tooth extraction, which was followed two weeks later by the sudden onset of left-sided frontotemporal headache radiating down the face, left ear fullness with associated hearing loss, toothache, and left orbital pain. Read More

J Surg Case Rep 2019 Apr 3;2019(4):rjz093. Epub 2019 Apr 3.

ENT Department, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, UK.

Mastoiditis caused by mycobacterium tuberculosis (TB) has an extremely low incidence in paediatric patients and intracranial complications are even rarer. We report the case of a 2-year-old Caucasian male who presented to a tertiary ENT centre with a left sided mastoid swelling and drowsiness after having been treated unsuccessfully for unresolving ear pain and discharge for 6 weeks. He was subsequently found to have mastoiditis with intracranial complications caused by mycobacterium TB. Read More

Vestn Otorinolaringol 2019 ;84(1):28-30

Department of Otorhinolaryngology, Pediatric Faculty of the N.I. Pirogov Russian National Research Medical University, Moscow, Russia, 117997; Morozovskaya City Children's Clinical Hospital, Moscow Health Department, Moscow, Russia, 119049.

This article was designed to report the results of the analysis of the cases of chronic otitis media complicated by mastoiditis in the children admitted to the Morozovskaya City Children's Clinical Hospital for the examination and treatment during the period from 2009 till 2017. The objective of the present study was to evaluate the clinical significance and the optimal time schedule of computed tomography (CT) of the temporal bones in the patients with suspicion of mastoiditis for the determination of the indications for their surgical treatment. All the patients were divided into three groups differing in the severity of clinical manifestations of the disease. Read More

Case Rep Radiol 2019 19;2019:7876494. Epub 2019 Feb 19.

Department of Radiology, Galway University Hospitals, Galway, Ireland.

Pneumocephalus in the absence of trauma, tumour, or surgery is a rare entity. We report a case of a 73-year-old lady who presented with sepsis leading to confusion and unresponsiveness. A CT of brain revealed mastoiditis, sinusitis, and associated pneumocephalus. Read More

Case Rep Otolaryngol 2019 14;2019:9641945. Epub 2019 Feb 14.

ENT Department, "P. & A. Kyriakou" Children's Hospital of Athens, Athens, Greece.

We present a rare case of transplacental-transmitted maternal melanoma to the placenta and foetus during the pregnancy of a 34-year-old woman. She was diagnosed with a melanoma at the age of 25, for which she was treated with chemotherapy. During her pregnancy, she presented with a recurrence of the disease and died 3 months after delivery. Read More

Health Technol Assess 2019 Mar;23(11):1-70

School of Population Health and Environmental Sciences, King's College London, London, UK.

Background: Unnecessary prescribing of antibiotics in primary care is contributing to the emergence of antimicrobial drug resistance.

Objectives: To develop and evaluate a multicomponent intervention for antimicrobial stewardship in primary care, and to evaluate the safety of reducing antibiotic prescribing for self-limiting respiratory infections (RTIs).

Interventions: A multicomponent intervention, developed as part of this study, including a webinar, monthly reports of general practice-specific data for antibiotic prescribing and decision support tools to inform appropriate antibiotic prescribing. Read More

Otol Neurotol 2019 Apr;40(4):471-477

Division of Otolaryngology-Head and Neck Surgery.

Objective: Otogenic brain abscess is a well-recognized clinical condition that describes brain abscess secondary to an ear infection or mastoiditis. Current evidence remains limited on risk factors associated with mortality as most data are from case series. We aimed to 1) report the mortality rate among patients who did and did not receive mastoidectomy 2) identify factors associated with inpatient mortality. Read More

An Pediatr (Barc) 2019 Mar 2. Epub 2019 Mar 2.

Sección de Enfermedades Infecciosas, Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Madrid, España; Universidad Complutense de Madrid, Madrid, España.

Introduction: Invasive group A streptococcal disease (iGASD) is a serious infection in children. Several studies have shown an increased incidence in the past years.

Objective: To evaluate the characteristics and outcome of iGASD in children, and to determine changes in incidence or severity. Read More

Am J Case Rep 2019 Mar 2;20:274-277. Epub 2019 Mar 2.

Department of Medicine, Charleston Area Medical Center, Charleston, WV, USA.

BACKGROUND Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke. CVST can be caused by systemic conditions as well as mechanical factors that reduce blood flow to promote thrombosis. These can include hormonal therapies, pregnancy, malignancy, genetic conditions. Read More

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

f Department of Anthropology , Museo Nacional de Historia Natural , Santiago , Chile.

Background: This study evaluates otitis media in prehistoric populations in northern Chile.

Aims/objectives: Determining prevalence of otitis media and diagnostic usefulness of temporal-bone X-rays in skulls.

Materials And Methods: 444 skulls belonging to three groups: prehistoric-coastal (400-1000 AD), prehistoric-highland (400-1000 AD) and Pisagua-Regional Developments (1000-1450 AD). Read More

Am J Emerg Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Emergency Medicine, Geisinger Health System, 100 North Academy Ave., Danville, PA 17822-2005, USA.

Otalgia with mastoiditis is an infrequently encountered complication of acute otitis media (Pfaff and Moore, 2018). Even more rare is the development of infected jugular venous thrombosis, Lemierre's disease. We present a case of a six year-old girl with otalgia for over two months who presented to our Emergency Department (ED) with clinical mastoiditis, confirmed on CT scan, as well as an incidental diagnosis of complete thrombosis of the internal jugular (IJ) vein, Lemierre's syndrome. Read More

Anaerobe 2019 Apr 14;56:95-97. Epub 2019 Feb 14.

Marmara University, School of Medicine, Department of Microbiology, Istanbul, Turkey.

We have reported a case of mastoiditis which progressed to meningitis in a 16-year old male patient. CSF (cerebrospinal fluid) anaerobic culture revealed four species of isolated anaerobic bacteria. This is the first case in the literature in which a patient survived childhood polymicrobial anaerobic meningitis diagnosed by MALDI-TOF MS (Matrix Assisted Laser Desorption Ionization - Time of Flight Mass Spectrometry). Read More

Acta Otorhinolaryngol Ital 2019 Jan 31. Epub 2019 Jan 31.

Otorhinolaryngology and Otoneurosurgery Department, University Hospital of Parma, Italy.

The association between external auditory canal osteoma and external auditory canal cholesteatoma is rare, with only a few reports in the current literature. Intracranial complications are very rare in the external auditory canal cholesteatoma, especially with direct propagation through the internal auditory canal. A case of 27-year-old male presenting with external auditory canal osteoma with secondary external auditory canal cholesteatoma is described. Read More

Orv Hetil 2019 Jan;160(4):151-157

Klinikai Központ, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Munkácsy M. u. 2., 7621.

Wegener's granulomatosis - or, in other words, granulomatosis with polyangiitis - is an anti-neutrophil cytoplasmic antibody associated granuloma forming vasculitis, mainly affecting the respiratory tract and the renal system. Otologic manifestations of Wegener's disease can be otitis media with effusion or chronic silent mastoiditis with conductive hearing loss, but sensorineural hearing loss can also evolve. The diagnosis is based on the clinical appearance as well as the immunoserological and histopathological results. Read More

Rev Med Suisse 2019 Jan;15(N° 632-633):78-81

Service d'ORL et de chirurgie cervico-faciale, HUG, 1211 Genève 14.

The articles have been again selected among more than 15 000 abstracts and the review aims to be generalist. Interest of honey in head and neck pathologies, apnea syndrome, tonsillectomy and immunotherapy. In otology, middle ear infections and mastoiditis, cochlear implant in the elderly, deafness in children, auto-evaluation of audition and new perspectives regarding ciliar cell cultures. Read More

Clin Case Rep 2019 Jan 4;7(1):186-188. Epub 2018 Dec 4.

Pediatric resident PGY-2 Dayton Children's Hospital Dayton Ohio.

Otogenic cerebral sinovenous thrombosis (CSVT) is a rare complication of otitis media and associated with significant morbidity and mortality. Classic clinical signs of mastoiditis (pain, swelling, and erythema posterior to the pinna) are not always present at presentation. Treatment of otogenic CSVT consists of conservative surgery, antibiotics, and anticoagulation. Read More

BMC Infect Dis 2018 Dec 20;18(1):686. Epub 2018 Dec 20.

Semmelweis University, Institute of Medical Microbiology, Budapest, Hungary.

Background: Central nervous system (CNS) infections caused by Actinomyces spp. including brain abscess, actinomycoma, subdural empyema and epidural abscess are well described, however reports of Actinomyces-associated meningitis are scarcely reported.

Case Report: We present the case of a 43-year-old Hungarian male patient with poor socioeconomic status who developed acute bacterial meningitis caused by Actinomyces turicensis originating from the left side mastoiditis. Read More

Laryngoscope 2019 Apr 20;129(4):852-857. Epub 2018 Dec 20.

Department of Otolaryngology/Facial Plastic Surgery, Beaumont Health System, Farmington Hills, Michigan, U.S.A.

Objectives/hypothesis: To investigate whether radiologist-produced imaging reports containing the terms mastoiditis or mastoid opacification clinically correlate with physical examination findings of mastoiditis. Additionally, to investigate whether and how often otolaryngology was unnecessarily consulted and inappropriate antibiotic therapy was initiated.

Study Design: Retrospective chart review within a large community hospital setting. Read More

Iran J Otorhinolaryngol 2018 Nov;30(101):361-364

Department of Otorhinolaryngology, University Putra Malaysia (UPM), Selangor, Malaysia.

Introduction: Metastatic tumors of the temporal bone are extremely rare. Collet-Sicard syndrome is an uncommon condition characterized by unilateral palsy of the lower four cranial nerves. The clinical features of temporal bone metastasis are nonspecific and mimic infections such as chronic otitis media and mastoiditis. Read More

Int J Pediatr Otorhinolaryngol 2019 Jan 23;116:210. Epub 2018 Oct 23.

Paparella Ear, Head & Neck Institute, 701 25th Ave. S. Suite 200, Minneapolis, MN, 55454, USA.

Int J Pediatr Otorhinolaryngol 2019 Jan 22;116:209. Epub 2018 Oct 22.

Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland; Department of Otorhinolaryngology, Regional Hospital, Kielce, Poland. Electronic address:

J Pediatric Infect Dis Soc 2018 Nov 21. Epub 2018 Nov 21.

Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.

Background: Few data on intracranial group A Streptococcus (GAS) infection in children are available. Here, we describe the demographic, clinical, and diagnostic characteristics of 91 children with intracranial GAS infection.

Methods: Cases of intracranial GAS infection in persons ≤18 years of age reported between 1997 and 2014 were identified by the Centers for Disease Control and Prevention's population- and laboratory-based Active Bacterial Core surveillance (ABCs) system. Read More

Eur Arch Otorhinolaryngol 2019 Feb 12;276(2):611-612. Epub 2018 Nov 12.

Department of Diagnostic and Interventional Radiology, Evangelisches Krankenhaus Göttingen-Weende, An der Lutter 24, 37074, Göttingen, Germany.

Incidental findings are common on patients undergoing magnetic resonance imaging (MRI) of the brain. Fluid signal in the mastoid can be such an incidental finding on MRI of the brain. In only a small number of patients, this relates to inflammatory disease of the middle ear or mastoid. Read More

Case Rep Otolaryngol 2018 17;2018:7639784. Epub 2018 Oct 17.

Department of ENT, Zain and Al Sabah Hospitals, Kuwait City, Kuwait.

Lymphoma originating from the middle ear is rare. The diagnosis of lymphoma as with other cancers of the temporal bone is often made late, and this has a negative implication on the treatment and prognosis of the condition. The delay of diagnosis is mainly due to the similar presentation shared with other benign conditions of the middle ear. Read More

Scand J Rheumatol 2018 Nov 5:1-7. Epub 2018 Nov 5.

a Department of Nephrology and Rheumatology , Gunma University Graduate School of Medicine , Gunma , Japan.

Objective: We aimed to describe the clinical characteristics and treatment course of hypertrophic pachymeningitis (HPM) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

Methods: We retrospectively analysed 15 patients (11 men and four women). HPM was diagnosed based on thickening and enhancing of the brain and/or spinal dura mater on gadolinium-enhanced magnetic resonance imaging (MRI) T1 sequence. Read More

J Laryngol Otol 2018 Nov 5;132(11):1010-1012. Epub 2018 Nov 5.

Otolaryngology Department,Southend University Hospital NHS Foundation Trust,Westcliff-on-Sea,UK.

Objectives: To determine: (1) the incidence of incidental 'mastoiditis' reported on magnetic resonance imaging scans performed in patients with asymmetrical sensorineural hearing loss and/or unilateral tinnitus; (2) how many of those patients have actual otological pathology and/or require treatment; and (3) the financial implications of such a reporting practice.

Method: Retrospective case series.

Results: Between October 2015 and November 2016, 500 patients underwent magnetic resonance imaging of the internal auditory meatus to rule out cerebellopontine angle lesions. Read More

Am J Med 2019 Feb 25;132(2):e39-e40. Epub 2018 Oct 25.

Department of Pulmonary, Critical Care and Sleep Medicine, MedStar Georgetown University Hospital, Washington, DC.

Med Clin North Am 2018 Nov 20;102(6):1109-1120. Epub 2018 Sep 20.

Otolaryngology-Head and Neck Surgery, University of California, San Francisco, 2233 Post Street, 3rd floor, San Francisco, CA 94115, USA.

Infections of the head and neck are common and appropriately managed by primary care providers in most cases. However, some infections are associated with significant morbidity and require urgent recognition and management by specialty services. These include deep neck space infections originating in the oral cavity, pharynx, and salivary glands, as well as complicated otologic and sinonasal infection. Read More

Ann R Coll Surg Engl 2019 Jan 16;101(1):e23-e25. Epub 2018 Oct 16.

Royal Devon and Exeter NHS Foundation Trust , UK.

We describe a rare case of cervical necrotising fasciitis caused by mastoiditis and Bezold's abscess. This case was complicated by a tracheostomy delaying wound healing. A novel strategy to repair the tracheotomy defect using Permacol™, an acellular porcine dermal substitute, and a local muscle flap not previously reported in the literature is described to allow the use of negative pressure wound therapy dressing. Read More

Br J Neurosurg 2018 Oct 8:1-5. Epub 2018 Oct 8.

d Department of Otorhinolaryngology, Head and Neck Surgery , University of Bonn , Bonn , Germany.

Objective: Sarcoidosis is a multisystemic granulomatous disease of unknown cause which affects the lung or bilateral hilar lymphadenopathy in over 90% of the cases. Neurosarcoidosis (NS) is rare and accounts for approximately 5 - 15% of the cases. Involvement of all parts of the central and peripheral nervous system is possible with various clinical symptoms, e. Read More

Laryngoscope 2019 Mar 4;129(3):754-760. Epub 2018 Oct 4.

Department of Otolaryngology-Head and Neck Surgery, Cleveland Clinic, Cleveland, Ohio.

Objective: There is no standard of care for treatment of pediatric acute mastoiditis (PAM). We systematically reviewed the English literature to evaluate the efficacy of PAM treatment options.

Methods: PubMed, Embase, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library were searched from inception to January 2016, along with manual bibliography searches, for studies describing surgical or medical therapy. Read More

J Cancer Res Ther 2018 Jul-Sep;14(5):1152-1153

Department of Neurology, Medeniyet University, Medical Faculty, Istanbul, Turkey.

The early diagnosis of very rare nasopharyngeal carcinoma (NPC) is so difficult, to surrounded by structures such as the orbital skull base. With the invasion of the disease, the symptoms are manifested in different ways so that it may be confusion and delay in diagnosis and treatment in this situation. Including otological symptoms (serous otitis media), Gradenigo's syndrome is a rare clinical condition. Read More

Pan Afr Med J 2018;30:34. Epub 2018 May 16.

Prosper-Hospital, Department of Oto-rhino-laryngology, Head and Neck Surgery, Recklinghausen, Germany.

Pediatr Neurosurg 2018 24;53(5):317-321. Epub 2018 Aug 24.

Department of Neurosurgery, Children's Minnesota, St. Paul, Minnesota, USA.

Background: Rhabdomyosarcoma originating in the mastoid is rare and may be misdiagnosed as an infectious mastoiditis due to overlapping clinical and imaging features. We aimed to identify distinguishing characteristics to facilitate earlier diagnosis and treatment.

Method: Here we describe a case report and a systematic review of 23 reports describing previous cases of mastoid rhabdomyosarcoma. Read More

Otol Neurotol 2018 Sep;39(8):1005-1011

Department of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.

Objective: Complications due to acute otitis media (AOM), while rare, are associated with significant morbidity and are not well characterized from an epidemiological perspective. We analyze the pattern of presentation and emergency department (ED) utilization in patients with AOM and associated complications.

Study Design: Retrospective analysis of the Nationwide Emergency Department Sample (NEDS) from 2009 to 2011. Read More

Acta Neurochir (Wien) 2018 Oct 1;160(10):2055-2062. Epub 2018 Aug 1.

Neurosurgical Department, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

Background: Due to improved diagnostic methods, the incidence of brain abscess is still rising. Therefore, clear and evidence-based therapy for the patients who suffer from brain abscesses is necessary. Brain abscesses are potentially life-threatening conditions that possibly lead to permanent injuries even after sufficient healing has taken place. Read More

Braz J Otorhinolaryngol 2018 Jul 17. Epub 2018 Jul 17.

Nicolaus Copernicus University Hospital of Bydgoszcz, Department of Health Sciences, Department of Phoniatrics and Audiology, Bydgoszcz, Poland.

Introduction: Acute mastoiditis remains the most common complication of acute otitis media. It may rarely appear also in cochlear implant patients. However, the treatment recommendations for this disease are not precisely defined or employed, and in the current literature the differences regarding both the diagnosis and management are relatively substantial. Read More

Laryngorhinootologie 2018 Jul 9;97(7):497-508. Epub 2018 Jul 9.

A number of diseases of the middle ear are summed up under the term otitis media: acute otitis media, recurrent acute otitis media, otitis media with effusion, chronic suppurative otitis media and chronic otitis media epitympanalis (= cholesteatoma). Acute otitis media belongs to the most common pediatric diseases and is often caused by bacterial infection. Since the advent of pneumococcal vaccines the quantity of AOM caused by pneumococci has declined; vaccination against NTHi and Moraxella catarrhalis are being developed. Read More

Int J Pediatr Otorhinolaryngol 2018 Aug 6;111:142-148. Epub 2018 Jun 6.

Paparella Ear, Head & Neck Institute, 701 25th Ave. S. Suite 200, Minneapolis, MN, 55454, United States.

Objectives: Recurrent acute mastoiditis is repeatedly reported in the literature, but data to understand the pathogenesis, update treatment recommendations and inform future trials are sparse due to the infrequency of the disease.

Methods: A retrospective chart review from 2001 to 2016 was conducted including 73 children treated for acute mastoiditis. A follow-up survey was attempted for each patient. Read More

Eur Arch Otorhinolaryngol 2018 Aug 8;275(8):1971-1977. Epub 2018 Jun 8.

Audiology and Otosurgery Unit, Department of Surgery, Cochlear Implant Referral Center, "Bambino Gesù" Pediatric Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.

Purpose: To describe the prevalent clinical, laboratory, and radiological features of otogenic lateral sinus thrombosis (OLST) in children; to identify clinical predictors of outcome; to propose a management algorithm derived from experience.

Methods: A retrospective review was conducted of the clinical records of patients with OLST, treated in a single tertiary care referral center for pediatric disease from 2006 to 2017. The inclusion criteria were pediatric age (0-16 years) and OLST diagnosis confirmed by a pre- and post-contrast CT or venography-MRI scan. Read More

Ital J Pediatr 2018 Jun 18;44(1):71. Epub 2018 Jun 18.

Pediatric Emergency Unit, Azienda Ospedaliera - Universitaria di Bologna, Policlinico Sant'Orsola - Malpighi, via Massarenti 10, 40100, Bologna, Italy.

Background: Acute mastoiditis is the main suppurative complication of acute otitis media. Its incidence ranges from 1.2 to 4. Read More

Case Rep Otolaryngol 2018 20;2018:8702532. Epub 2018 Mar 20.

Anesthesiology/Reanimation Clinic, University Clinical Center of Kosova, Prishtina, Kosovo.

Bezold's abscess is a very rare extracranial complication of acute mastoiditis. Lateral sinus thrombosis is another intracranial complication of acute mastoiditis that can occur, but there are only few reports of concomitant ispilateral Bezold's abscess and lateral sinus thrombosis with favorable outcome. We diagnosed and treated successfully a 14-year-old girl suffering from acute mastoiditis complicated with Bezold's abscess and lateral sinus thrombosis. Read More

Pediatr Infect Dis J 2018 Oct;37(10):1048-1053

The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Background: The introduction of the pneumococcal conjugated vaccines (PCVs) resulted in a substantial reduction of invasive pneumococcal disease (IPD) rates. However, impact on nonsevere IPD (mostly occult bacteremia) has not yet been fully elucidated. We assessed severe and nonsevere IPD (SIPD and NSIPD, respectively) rate dynamics in children < 5 years in Israel before and after PCV7/PCV13 implementation. Read More

Pediatr Rev 2018 May;39(5):267-269

Landstuhl Regional Medical Center, Landstuhl, Germany.

Medicine (Baltimore) 2018 Apr;97(17):e0521

Division of Rheumatology, Department of Internal Medicine.

Rationale: Hypertrophic pachymeningitis (HP) is an uncommon, life-threatening disease that is seen in elderly patients with antineutrophil cytoplasmic antibody (ANCA) positivity. Proteinase-3 (PR3)-ANCA-positive HP has not been reported in adolescents. Here, we report the first case of adolescent PR3-ANCA-positive HP successfully treated with immunosuppressive therapy. Read More

Braz J Otorhinolaryngol 2018 Apr 14. Epub 2018 Apr 14.

Ondokuz Mayis University Faculty of Medicine, Department of Radiology, Samsun, Turkey.

Introduction: Otitis media, mastoiditis or the pressure effect of tumorous lesions such as cholesteatoma can be the cause of facial canal dehiscence and facial nerve paralysis. The most common segment involved in dehiscence is the tympanic segment and the second most common is the lateral aspect of the facial canal in the oval window area.

Objective: To determine the prevalence of the facial canal dehiscence and the relationship between the angle at the second genu of the facial nerve and facial canal dehiscence. Read More

Rev Esp Quimioter 2018 Jun 26;31(3):278-281. Epub 2018 Apr 26.

Mónica de Frutos, Servicio de Microbiología. Hospital Universitario Rio Hortega Calle Dulzaina, 2 47012 Valladolid, Spain.

Objective: Turicella otitidis is a gram-positive bacillus coryneforme described, after 16S RNA sequencing, in 1994 by Funke et al as a microorganism involved in otitis media, and it is in health conditions a habitual colonizer of the external auditory canal. Since its description, more than twenty years ago, few cases of otitis related to or directly attributed to this microorganism have been published.

Methods: Description of a case of mastoiditis that required surgery and other cases of otic pathology in which T. Read More

BMJ Case Rep 2018 Apr 21;2018. Epub 2018 Apr 21.

Department of Internal Medicine, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Q fever is a zoonotic disease caused by that usually presents with non-specific or benign constitutional symptoms. Diagnosis is often challenging and, after acute Q fever, 1%-5% of patients can develop chronic disease. We present an 80-year-old male patient who was admitted due to a 3 months history of fever, productive cough, myalgia, weight loss, headache and hearing loss. Read More

Int J Pediatr Otorhinolaryngol 2018 May 1;108:132-136. Epub 2018 Mar 1.

Pediatric Otolaryngology, Division of Head and Neck Surgery and Communication Sciences, Department of Surgery, Duke University Medical Center, Durham, NC, USA.

Objective: To examine preoperative risk factors, postoperative 30-day outcomes and adverse events of acute mastoiditis using a national pediatric surgical database.

Methods: We explored our objectives using a cross-sectional analysis of a hospital-based reporting system database. The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) pediatric database was used to identify surgical encounters for the treatment of acute mastoiditis from 2012 to 2015. Read More