Hum Pathol 2022 May 10;126:55-62. Epub 2022 May 10.
Instituto D'Or de Pesquisa e Ensino (IDOR), São Paulo, 04501-000, Brazil; Laboratory of Investigative Pathology, CIPED, University of Campinas (Unicamp), Campinas, São Paulo, 13083-887, Brazil; Anatomic Pathology D'Or Hospitals Network, São Paulo, 04321-120, Brazil; Multipat Laboratory of Pathology, Campinas, São Paulo, 13086-130, Brazil.
Systemic mastocytosis (SM) is a myeloid neoplasm characterized by abnormal growth and accumulation of neoplastic mast cells in at least one extracutaneous site. Clinical presentation and course are variable, most patients are developing an indolent disease and some, an aggressive/leukemic form. Because of its rarity, most physicians are unfamiliar with this disease and do not readily diagnose it. Read More