285 results match your criteria Marchiafava-Bignami Disease


[Mild Encephalopathy with Reversible Splenial Lesion(MERS)].

Authors:
Aki Sato

No Shinkei Geka 2021 Mar;49(2):413-417

Department of Neurology, Niigata City General Hospital.

Mild encephalitis/encephalopathy with a reversible splenial lesion(MERS)is a clinically and radiologically benign condition that has been described within the past two decades. MRI findings include isolated symmetrical ovoid lesions of the splenium with a high-intensity signal on DWI and decreased apparent diffusion coefficient. These findings have been associated with viral infections, epilepsy, antiepileptic drug usage, and metabolic disturbances, among others. Read More

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Rare case of Marchiafava-Bignami disease due to thiamine deficiency and malnutrition.

BMJ Case Rep 2020 Dec 10;13(12). Epub 2020 Dec 10.

Family Medicine, The University of Alabama System, Tuscaloosa, Alabama, USA.

Marchiafava-Bignami disease (MBD) is a rare, toxic demyelinating disorder of the central nervous system associated with chronic alcoholism and malnutrition. The clinical presentation is varied and non-specific, including symptoms of acute dementia, impaired consciousness, dysarthria, hemiparesis, pyramidal tract signs, seizure activity, ataxia and signs of interhemispheric disconnection. The differential diagnosis of MBD may include Wernicke's encephalopathy, multiple sclerosis, encephalitis, infectious or paraneoplastic leucoencephalopathy, infarction, Alzheimer's disease, multi-infarct dementia and frontotemporal lobar degeneration (Pick) disease. Read More

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December 2020

Marchiafava-Bignami Disease Associated with Spinal Involvement.

Case Rep Neurol Med 2020 28;2020:8867383. Epub 2020 Oct 28.

Department of Neurology, Sanatorio Güemes-University Hospital, Buenos Aires, Argentina.

Marchiafava-Bignami disease (MBD) is a rare disorder of unknown etiology, strongly associated with alcoholism and malnutrition. MBD causes primary involvement of the corpus callosum, leading to confusion, dysarthria, seizures, and frequent death. We report the case of a 54-year-old male without a history of alcoholism or known malabsorption disease, who presented with altered consciousness and neurologic impairment. Read More

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October 2020

Marchiafava-Bignami disease-like corpus callosum lesions due to moyamoya disease.

Neurol Sci 2021 03 7;42(3):1161-1164. Epub 2020 Sep 7.

Department of Diagnostic and Interventional Radiology, University Hospital Center Zagreb, School of Medicine, University of Zagreb, Kišpatićeva 12, 10000, Zagreb, Croatia.

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Depression preceding Marchiafava-Bignami disease.

Aust N Z J Psychiatry 2021 02 28;55(2):224-225. Epub 2020 Jul 28.

Department of Psychiatry & Mental Health, Tunku Abdul Rahman Institute of Neuroscience, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.

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February 2021

Diverse MRI findings and clinical outcomes of acute Marchiafava-Bignami disease.

Acta Radiol 2020 Jul 27:284185120943040. Epub 2020 Jul 27.

Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.

Background: The acute onset of Marchiafava-Bignami disease (MBD) is difficult to capture, and its clinical manifestations are overlapped. Magnetic resonance imaging (MRI) is very useful in the diagnosis of acute MBD.

Purpose: To investigate the MRI features and clinical outcomes of acute MBD. Read More

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Simultaneous acute Marchiafava-Bignami disease and posterior reversible encephalopathy syndrome: a case almost misdiagnosed.

Quant Imaging Med Surg 2020 Jun;10(6):1392-1395

Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.

Marchiafava-Bignami disease (MBD) is a rare neurological disease, and is characterized by callosal lesions consisting of necrosis and demyelination. Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome, and refers to a disorder with reversible subcortical vasogenic brain edema, predominantly involving the bilateral parieto-occipital regions. Never before had articles reported that the two diseases occurred simultaneously. Read More

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Reversible lesion in the splenium of the corpus callosum in a patient with chronic alcoholism.

J Gen Fam Med 2020 May 18;21(3):84-86. Epub 2020 Apr 18.

Department of Neurology International University of Health and Welfare Hospital Nasushiobara Japan.

Marchiafava-Bignami disease (MBD) is often diagnosed in chronic alcoholics. The disease processes typically involve the corpus callosum and clinically presents with various manifestations on the basis of clinical condition, extent of the splenium of the corpus callosum involvement at brain magnetic resonance imaging (MRI), and prognosis. We report a patient affected by MBD, who presented an isolated reversible splenial lesion at brain MRI and achieved a favorable recovery. Read More

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Marchiafava-Bignami Disease: Two Chronologically Distinct Stages in the Same Patient.

Can J Neurol Sci 2020 09 30;47(5):689-690. Epub 2020 Apr 30.

Neuroradiology Department, Hospital de Braga, Braga, Portugal.

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September 2020

Comprehensive neuropsychological findings in a case of Marchiafava-Bignami disease.

Clin Neuropsychol 2020 Feb 26:1-12. Epub 2020 Feb 26.

Department of Psychiatry, University of Illinois College of Medicine, Chicago, IL, USA.

Marchiafava-Bignami disease (MBD) is a rare complication associated with chronic heavy alcohol use, with case reports documenting a range of cognitive outcomes. Given the variability in MBD presentation and outcomes, milder cases may remain undiagnosed and few studies or case reports have presented a comprehensive neuropsychological profile of these patients. The objective of this case study was to describe the neuropsychological presentation and findings of a case of likely MBD. Read More

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February 2020

Marchiafava-Bignami disease: Report of three cases.

Ideggyogy Sz 2020 Jan;73(1-2):65-69

Bakırkoy Prof. Dr. Mazhar Osman Mental and Neurological Diseases Training and Research Hospital, Istanbul, Turkey.

Marchiafava-Bignami disease (MBD) is a rare alcohol-associated disorder characterized by demyelination and necrosis of the corpus callosum. We report three patients who had history of chronic alcoholism, different clinical presentation and MRI findings consistent with the diagnosis of Marchiafava-Bignami disease. Read More

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January 2020

Marchiafava Bignami Disease - A Case Report.

J Assoc Physicians India 2020 Jan;68(1):61

SRM Medical College Hospital and Research Institute.

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January 2020

Neuroimaging of Multiple Sclerosis Mimics.

Neurol Clin 2020 02 24;38(1):149-170. Epub 2019 Oct 24.

Dent Neurological Institute, Buffalo, NY, USA.

Multiple sclerosis (MS) is the most common immune-mediated disease of the central nervous system, characterized by demyelinating lesions of the brain and the spinal cord. Although it is extremely important to diagnose this condition in a timely manner, to initiate and monitor treatment to prevent permanent neurologic damage and disability, it is also necessary that other demyelinating conditions collectively referred to as MS mimics be identified and excluded. This article describes the in-depth neuroimaging characteristics and morphology of the pathologic lesions on the various neuroimaging modalities. Read More

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February 2020

Marchiafava-Bignami Disease in a Patient with No Alcohol Abuse.

Neurol India 2019 Jul-Aug;67(4):1169

Department of Emergency Medicine, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.

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October 2020

Marchiafava-Bignami disease with haemophagocytic lymphohistiocytosis as a postoperative complication of cardiac surgery.

BMJ Case Rep 2019 Aug 26;12(8). Epub 2019 Aug 26.

Neurological Science, Tohoku University School of Medicine, Sendai, Miyagi, Japan.

Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism; however, MBD in a non-alcoholic diabetic patient has rarely been reported. The aetiology or pathophysiology of MBD is still unknown. A 50-year-old man with a history of untreated diabetes mellitus underwent on-pump beating coronary artery bypass graft surgery (CABG) surgery for three-vessel and left main coronary disease. Read More

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Intermittent alien hand syndrome caused by Marchiafava-Bignami disease: A case report.

Medicine (Baltimore) 2019 Aug;98(34):e16891

Department of Neurology, The First Hospital of Jilin University, Changchun.

Rationale: Alien Hand syndrome (AHS) is characterized in most patients by seemingly purposeful, involuntary movements of the extremities. It is not well known among physicians on account of its diverse clinical manifestations.

Patient Concerns: We present a 57-year-old Chinese man who could not stop or turn himself around as he involuntarily and uncontrollably walked forward, which had happened frequently in the month prior to treatment. Read More

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"CHOICES": An acronym to aid in delineating potential causes of non-metabolic, non-infectious acute toxic leukoencephalopathy.

Eur J Radiol Open 2019 28;6:243-257. Epub 2019 Jun 28.

Department of Radiology, Division of Neuroradiology, University of Minnesota Medical Center, Minneapolis, MN, USA.

Purpose: To describe non-metabolic, non-infectious etiologies of acute toxic leukoencephalopathy (ATL) on DWI MRI, and provide a useful acronym to remember them.

Material And Methods: Our PACS archive was reviewed, yielding 185 patients with suspected ATL per MRI reports and clinical follow up; infectious or metabolic causes were excluded.

Result/discussion: The 87 included non-infectious, non-metabolic ATL patients' etiologies are represented by the acronym 'CHOICES': chemotherapy ('C',n = 34); heroin-induced ('H',n = 6), opioid analogues ('O',n = 14); immunosuppressant ('I',n = 11) or imidazole (n = 2); cocaine ('C',n = 1); environmental or ethanol abuse ('E',n = 5), splenial lesions ('S',n = 9), and 'other' (n = 5). Read More

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Clinical and neuroradiological features of 15 patients diagnosed with Marchiafava-Bignami disease.

Chin Med J (Engl) 2019 Aug;132(15):1887-1889

Department of Neurology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.

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Antemortem histopathology and imaging findings in a case of Marchiafava-Bignami disease.

J Clin Neurosci 2019 Aug 6;66:273-275. Epub 2019 Jun 6.

Department of Neurosurgery, Westmead Hospital, University of Sydney, Australia.

Marchiafava-Bignami disease (MBD) is a rare condition often associated with chronic alcohol abuse. Clinical presentation is diverse. Characteristic magnetic resonance imaging (MRI) changes in the corpus callosum are the mainstay of radiological diagnosis. Read More

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White-matter commissures: a clinically focused anatomical review.

Surg Radiol Anat 2019 Jun 22;41(6):613-624. Epub 2019 May 22.

Anatomy Department, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.

Purpose: The objective of this review is to provide a structured approach to the main white matter commissures, their anatomic and radiological definition and disease implications.

Methods: The Pubmed database and The JAMA Network were used for the literature review and the following terms were searched using Sort by: Best Match and Sort by: Most Recent: telencephalic commissure, forebrain commissure anatomy, fornix anatomy, commissure of fornix, posterior commissure, corpus callosum, commissural agenesis, Probst bundle, corpus callosum disorders review, corpus callosum diseases review, Marchiafava-Bignami, Alzheimer's disease and Forel commissure; 36 papers were selected, one excluded due to the language barrier.

Results: The interhemispheric communication in the brain is achieved via the brain commissures, bundles of white matter linking the two cerebral hemispheres. Read More

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Overreligious beliefs with neuropsychiatric manifestations in a young lady-Rule out Marchiafava-Bignami disease.

Med J Armed Forces India 2019 Apr 15;75(2):228-231. Epub 2019 Apr 15.

Medical Officer, INS Circars, Vizag, India.

Marchiafava- Bignami disease is a rare condition characterized by demyelination of corpus callosum due to alcohol or malnutrition. Here we report a young lady who, due to her religious beliefs had stopped taking food and presented with neuropsychiatric manifestations. Neuroimaging was suggestive of Marchiafava Bignami disease and with adequate nutritional and thiamine therapy she had dramatic improvement clinically and had near complete resolution of lesions in neuroimaging. Read More

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Reversible MR Findings in Marchiafava-Bignami Disease.

Case Rep Neurol Med 2019 6;2019:1951030. Epub 2019 Feb 6.

Neuroimaging and Neurointervention Unit, NHS and University Hospital "Saint Mary alle Scotte", Siena, Italy.

Marchiafava-Bignami Disease (MBD) is a toxic demyelinating disease often diagnosed in chronic alcoholics. The disease process typically involves the corpus callosum and clinically presents with various manifestations resulting in MBD type A and type B on the basis of clinical condition, extent of callosal involvement and extracallosal involvement at brain magnetic resonance imaging (MRI), and prognosis. The death rate is high. Read More

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February 2019

Refractory Nonconvulsive Status Epilepticus with Favorable Outcome in a Patient with Marchiafava-Bignami Disease.

J Clin Neurol 2019 Jul 11;15(3):393-394. Epub 2019 Mar 11.

Department of Neurology, Seoul National University Hospital, Seoul, Korea.

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Gadolinium Enhancement May Indicate a Condition at Risk of Developing Necrosis in Marchiafava-Bignami Disease: A Case Report and Literature Review.

Front Hum Neurosci 2019 27;13:79. Epub 2019 Feb 27.

Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.

Marchiafava-Bignami disease (MBD) is a rare condition characterized by demyelination, necrosis and atrophy of the corpus callosum (CC), and mainly associated with alcoholism. MBD may present with various clinical manifestations. Brain magnetic resonance imaging (MRI) scan is important in prompt diagnosis and treatment of MBD. Read More

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February 2019

MR imaging in the diagnosis of Marchiafava-Bignami syndrome.

Neurol India 2019 Jan-Feb;67(1):321-323

Department of Radiology and Imaging, Holy Family Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

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January 2020

Left hemispatial neglect with a splenial lesion.

Neurocase 2018 08 28;24(4):220-226. Epub 2018 Oct 28.

d Neurology Service and GRECC , Malcom Randall Veterans Affairs Medical Center , Gainesville , FL , USA.

With injury of the anterior two-thirds of the corpus callosum, each hemisphere's attentional bias to contralateral hemispace becomes manifest with each hand deviating ipsilaterally during line bisection tasks. Patients with infarctions in the right posterior cerebral artery distribution with occipital and splenial damage can also exhibit spatial neglect. The goal of this report is to learn the role of the splenium of the corpus callosum in mediating visuospatial attention. Read More

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Bilateral middle cerebellar peduncles involvement a malnourished man with Marchiafava-Bignami disease.

Neurol Sci 2019 Feb 18;40(2):433-435. Epub 2018 Oct 18.

Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, Jiangxi Province, People's Republic of China.

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February 2019

A Case of Nonalcoholic Marchiafava-Bignami Disease with Left-Right Differential Agraphia of Chinese Characters.

Case Rep Neurol 2018 May-Aug;10(2):232-241. Epub 2018 Aug 29.

Department of Rehabilitation Medicine, Fukui General Hospital, Fukui City, Japan.

We report a 68-year-old right-handed female who was admitted to our hospital complaining chiefly of incontinence and decreased activity. Her brain images showed characteristics of Marchiafava-Bignami disease, such as symmetrical abnormal signals localized in the corpus callosum. The patient had no drinking habits. Read More

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Marchiafava-Bignami Disease Presenting as Acute Psychosis.

Indian J Psychol Med 2018 Sep-Oct;40(5):494-496

Department of Psychiatry, Jamaica Hospital Center, Jamaica, New York, USA.

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October 2018