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Head Neck Pathol 2019 Feb 13. Epub 2019 Feb 13.

Department of Oral Medicine and Pathology, Department of Dentistry, School of Health Sciences, National and Kapodistrian University of Athens, 2 Thivon Str, 11527, Goudi, Athens, Greece.

The aim of the present study is to report the demographic and clinical characteristics of all jaw cysts diagnosed in a single Oral Pathology Department. 5294 cases of jaw cysts diagnosed during a 38-year period were retrospectively collected and classified according to the latest classification of Head and Neck Tumors of the World Health Organization. The patients' gender and age, as well as the main clinical features of the cysts were retrieved from biopsy report forms. Read More

Cureus 2018 Oct 10;10(10):e3437. Epub 2018 Oct 10.

Otolaryngology, Aga Khan University Hospital, Karachi, PAK.

Introduction Ameloblastoma is a locally destructive tumor with a propensity for recurrence if not entirely excised. Management of ameloblastoma poses a challenge for all involved in the field of head and neck surgery because successful treatment requires not only adequate resection but also a functional and aesthetically acceptable reconstruction of the residual defect. Methods Patients who had histologically proven ameloblastoma between 1991 and 2009 were identified from the database of Aga Khan University Hospital. Read More

Cureus 2018 Sep 18;10(9):e3323. Epub 2018 Sep 18.

Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, IND.

Impacted teeth may not only interfere with function, but also can act as a source of many pathological lesions such as odontogenic cysts and tumors. One of the most prevalent types of odontogenic cysts associated with erupted, developing or impacted tooth is dentigerous cyst. Multiple impacted teeth with dentigerous cysts in both the maxillary and mandibular arches without the association of any syndromes is a very rare occurrence. Read More

Spec Care Dentist 2019 Jan 15;39(1):45-50. Epub 2018 Nov 15.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University, Ankara, Turkey.

Eosinophilic granuloma is the most common form of Langerhans cell histiocytosis and corresponds with bone lesions characterized by pain, rapid growth, and high tendency of recurrence after inadequate curettage. It is a rare disease that is difficult to diagnose clinically and radiographically because it mimics other odontogenic cysts and tumors. In this report, the reconstruction of an osseous defect with an iliac graft and a modified implant-supported hybrid prosthesis after surgical excision of an eosinophilic granuloma in the mandible of a 27-year-old male patient was described. Read More

Saudi Dent J 2018 Jan 31;30(1):94-96. Epub 2017 Oct 31.

Department of Oral and Maxillofacial Surgery, Government Dental College, Aurangabad, India.

Adenomatoid odontogenic tumour (AOT) is an uncommon, hamartomatous, benign epitheial lesion of odontogenic origin. The current World Health Organisation (WHO) classification of odontogenic tumors defines AOT as being composed of the odontogenic epithelium in a variety of histoarchitectural patterns, embedded in mature connective tissue stroma, and characterized by slow, but progressive growth. The aim of this paper is to present three rare cases of intraosseous AOTs with varied clinical and radiographic features imposing the fact that AOT should be included in differential diagnosis of routine odontogenic cysts and tumours. Read More

Int J Pediatr Otorhinolaryngol 2018 Sep 30;112:121-125. Epub 2018 Jun 30.

Oncologic Surgery Department, Centre Léon Bérard, Lyon, France. Electronic address:

Keratocystic odontogenic tumors (KCOT) are exceptional in children and adolescents as they usually occur in the third decade. The present study reports the case of a 15 years old girl who was diagnosed with a KCOT that underwent malignant transformation. KCOT diagnostic was based on clinical, radiological, histopathological and immunohistochemical findings. Read More

J Korean Assoc Oral Maxillofac Surg 2018 Jun 26;44(3):107-111. Epub 2018 Jun 26.

Institute of Translational Dental Sciences, Pusan National University, Yangsan, Korea.

Objectives: A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs. Read More

J Clin Exp Dent 2018 Jun 1;10(6):e542-e547. Epub 2018 Jun 1.

DDS, PhD, Professor, Postgraduate Program in Dentistry, School of Dentistry, Universidade de Pernambuco, Camaragibe, PE, Brazil.

Background: To identify the prevalence and clinicopathological profile of calcifying odontogenic cysts (COC) stored at an oral pathology service, and to analyze the immunoexpression of cyclooxygenase 2 (COX-2) and cyclin D1 (CD1) in these cysts.

Material And Methods: After a retrospective analysis (1990-2016) carried out to identify cases of COC, a sample of 12 cases was selected for immunohistochemical analysis of COX-2 and CD1 by the immunoperoxidase technique. Protein expression was evaluated semiquantitatively by attributing a score of 0 to 3 (0 = no staining; 1 = 1-25%; 2 = 26-50%, and 3 = >51% immunopositive cells). Read More

Gerodontology 2018 Dec 1;35(4):325-332. Epub 2018 Jun 1.

Postgraduate Program in Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Norte, Natal, Brazil.

Objective: The aim of this study was to investigate the frequency and some characteristics of odontogenic tumours, odontogenic cysts and non-odontogenic cysts in an elderly population (≥60 years).

Background: Few studies describe the distribution of oral lesions in older people.

Materials And Methods: A retrospective descriptive cross-sectional study was performed. Read More

Indian J Dent Res 2018 Mar-Apr;29(2):238-243

Department of Oral Pathology and Microbiology, Government Dental College, Kozhikode, Kerala, India.

Ghost cell odontogenic carcinoma (GCOC) is a malignant odontogenic epithelial tumor which is an exceedingly rare, highly aggressive, rapidly growing, and infiltrative tumor forming the malignant counterpart of long-standing benign cystic lesions coming in the spectrum of calcifying odontogenic cysts. To date, only a few cases have been reported in the medical literature. A case of unusual presentation of GCOC is presented and the clinical, histopathological, and immunohistochemical features are discussed along with a literature review. Read More

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S20-S23

Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India.

Orthokeratinized odontogenic cyst (OOC) is a relatively rare odontogenic cyst, distinct from odontogenic keratocyst (OKC). In the 4 edition of WHO Classification of Head and Neck Tumors (2017), OOC has been included as a separate entity in the category of developmental odontogenic cysts. It presents as a unilocular radiolucent lesion in the posterior mandible and is frequently related to impacted teeth, thus mimicking dentigerous cyst. Read More

Indian J Dent Res 2018 Jan-Feb;29(1):117-122

Department of Pathology, Graduate Program in Dentistry, Positivo University, Rua Professor Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, Paraná, Brazil.

Ameloblastoma is an aggressive odontogenic tumor which typically occurs between third and fourth decade of life that often needs resective approach. Immediate reconstruction may show better results. The treatment of multicystic ameloblastoma in the mandible being a rare case that occurred in the late second decade of life, which was surgically removed along with the affected teeth with safety margins, and the region was immediately reconstructed using a vascularized graft, removed from the fibula. Read More

J Craniomaxillofac Surg 2018 Mar 26;46(3):504-510. Epub 2017 Dec 26.

Department of Oral Surgery and Pathology, (Head: Dr. Henrique Pretti), School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address:

Purpose: To integrate the available data published on squamous odontogenic tumors (SOT) and squamous odontogenic tumor-like proliferations in odontogenic cysts (SOT-LPOC) into a comprehensive analysis of their clinical/radiologic features.

Materials And Methods: An electronic search was undertaken in January 2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm a definite diagnosis. Read More

BMJ Case Rep 2018 Jan 3;2018. Epub 2018 Jan 3.

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Keratocystic odontogenic tumour (KCOT) is considered one of the most aggressive odontogenic lesions presenting high recurrence rate which varies according to treatment modalities employed for management. The treatment rendered should have a lowest possible risk of recurrence and least morbidity while still eradicating the lesion. Although the radical treatment options like enucleation and en bloc resection are associated with lesser recurrences, these can lead to greater morbidity, especially in children with developing teeth and jaw bones, thus, emphasising need to consider more conservative treatment options like decompression and marsupialisation. Read More

Braz Oral Res 2017 Dec 18;31:e98. Epub 2017 Dec 18.

Universidade de São Paulo - USP, School of Dentistry, Department of Oral & Maxillofacial Surgery, Traumatology and Prosthesis, São Paulo, SP, Brazil.

The odontogenic keratocyst (OKC) is a recurrent cyst that has been recently reclassified from an odontogenic tumor to an odontogenic cyst. The aim of the present study was to investigate its treatment and address issues related to its association with nevoid basal cell carcinoma syndrome (NBCCS). Lesions from the cohort of patients included in the present study consisted of 40 OKCs, of which 27 lesions were treated by enucleation (GE) and 13 underwent decompression (GD). Read More

J Dent (Shiraz) 2017 Dec;18(4):259-264

Undergraduate Student, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Statement Of The Problem: It is necessary for surgeons and practitioners to know about relative incidence and clinicopathologic features of lesions for accurate diagnosis and approach of pathologic lesions. Data are limited about overall incidence of intra-osseous lesions of the jaws in Iranian patients.

Purpose: This study evaluated the clinicopathologic features of intra- osseous lesions of the jaws in an Iranian population, in a 22-year period. Read More

Quant Imaging Med Surg 2017 Oct;7(5):598-604

Jan Swasthya Sahyog, Hospital and Community Health Centre, Ganiyari, Bilaspur, Chhattisgarh, India.

Dentinogenic ghost cell tumors (DGCT) are very rare tumors considered as solid variants of calcifying epithelial odontogenic cysts (CEOC). They are locally invasive neoplasms and their main characteristic features are ameloblastoma like odontogenic epithelial proliferation, an aberrant keratinization in the form of ghost cells and dysplastic dentin. DGCT occur as two forms intraosseous (central) and extra osseous (peripheral), of which more aggressive intraosseous variety requires careful monitoring and aggressive local resection to prevent recurrence. Read More

J Dent (Tehran) 2017 May;14(3):132-137

Epidemiologist, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: The frequency of non-odontogenic lesions of the jawbones is lower than that of odontogenic lesions; however, study of the epidemiologic data of these lesions is required for health care programs. This study aimed to assess the relative frequency and demographic profile of non-odontogenic jaw lesions in an Iranian population over a 30-year period.

Materials And Methods: This archive review was performed using demographic and biopsy information of all patients with non-odontogenic lesions of the jawbones submitted to the Oral Pathology Department of Dental School of Tehran University of Medical Sciences from 1984 to 2014. Read More

Radiol Clin North Am 2018 Jan;56(1):45-62

Radiology and Imaging Sciences, Department of Surgical & Hospital Dentistry, University of Louisville, 501 South Preston Street, Louisville, KY 40202, USA.

Numerous benign cysts or solid tumors may present in the jaws. These arise from tooth-forming tissues in the dental alveolus or from nonodontogenic tissues in the basal bone of the mandible and maxilla. Radiologists provide 2 deliverables to assist in diagnosis and management: (1) appropriately formatted images demonstrating the location and extent of the lesion and (2) interpretive reports highlighting specific radiologic findings and an impression providing a radiologic differential diagnosis. Read More

Dent Update 2016 Nov;43(9):891-3

Gen Dent 2017 Nov-Dec;65(6):69-72

An ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor with histologic features of an ameloblastic fibroma in conjunction with the presence of dentin and enamel. It usually appears as a well-circumscribed radiolucency with radiopaque foci and slow growth and is commonly seen in children and young adults. A 13-year-old boy presented with an asymptomatic swelling in the posterior right region of the mandible and the right ascending ramus. Read More

Br J Oral Maxillofac Surg 2017 11 19;55(9):981-982. Epub 2017 Oct 19.

The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. Electronic address:

Ned Tijdschr Tandheelkd 2017 Oct;124(10):481-483

In the context of pain diagnostics, several lesions, partially radiolucent and partially opaque, were identified by chance in the mandible and maxilla. On the basis of the characteristic x-ray image, it was assumed to be cemento-osseous dysplasia. At an early stage, this cannot easily be distinguished from apical periodontitis. Read More

J Coll Physicians Surg Pak 2017 Sep;27(9):S110-S111

Department of Oral and Maxillofacial Pathology, NIMS Dental College, Jaipur, India.

Orthokeratinized odontogenic keratocyst (OOC) was first identified as orthokeratinized variant of odontogenic keratocyst in 1981 by Wright, due to its different histology and relatively low recurrence rate. Parakeratinized odontogenic cyst is now considered as keratocystic odontogenic tumor (KCOT) owing to its neoplastic nature. Although rare, calcification in the form of dystrophic calcification, dentinoid and cartilage has been reported in KCOT, but calcification in OOC is extremely rare and no case in English literature has been reported so far. Read More

J Contemp Dent Pract 2017 Aug 1;18(8):688-694. Epub 2017 Aug 1.

Department of Pathology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Aim: This study aimed at evaluating histological features of 52 cases of calcifying odontogenic cyst (COC), which is an uncommon benign odontogenic lesion. The World Health Organization (WHO) classified COC as a neoplasm and used the term calcifying cystic odontogenic tumor (CCOT) for benign cystic type and the dentinogenic ghost cell tumor (DGCT) for the benign solid-type lesions. There is no agreement regarding COC classification. Read More

Int J Oral Maxillofac Surg 2017 Nov 14;46(11):1490-1496. Epub 2017 Jul 14.

Department of Neurosciences, School of Dentistry, University of Padova, Padova, Italy.

The aim of this case series study was to illustrate the bone lid technique implemented using piezoelectric surgery to access mandibular alveolar bone diseases and to assess the clinical and radiographic outcomes. The technique was used to treat 21 consecutive patients with various conditions: cysts in six cases, impacted teeth with associated cysts in nine, keratocystic odontogenic tumours in three, impacted teeth in two, and an endodontic lesion in one. The bone lid was fashioned using piezoelectric surgery and a thin osteotomy insert. Read More

Braz J Med Biol Res 2017 Jul 10;50(8):e6209. Epub 2017 Jul 10.

Department of Oral and Maxillofacial Surgery, General Hospital of Xinjiang Military Region, Urumqi, China.

The aim of this study was to evaluate the feasibility of endoscopy to remove keratocystic odontogenic tumors (KCOTs) with virtual 3D mandibular images. Fifteen patients (mean age, 40.27±14. Read More

J Coll Physicians Surg Pak 2016 Nov;26(11):109-110

Department of Oral and Maxillofacial Surgery, Haydarpasa Teaching Hospital, Gulhane Military Academy of Medicine, Turkey.

Stafne bone cavity (SBC) is an uncommon lesion of the mandible; and generally found incidentally on routine radiographic examinations. The radiographic differential diagnosis of SBC includes a variety of lesions including odontogenic cysts, benign tumors, or bone metastases. In the present case, a 22-year female patient was admitted with chief complaint of pain in the right mandibular molar area. Read More

J Clin Pediatr Dent 2017;41(4):300-304

Multiple keratocystic odontogenic tumors (KCOT) occurred in a young child is challenging problem in the field of pediatric dentistry, and might have been related to nevoid basal cell carcinoma syndrome (NBCCS). Because of high recurrence rate of KCOTs, complete surgical resection is generally accepted as definitive treatment. However, complete surgical resection could induce negative effect on the development of permanent teeth and growth of jaw. Read More

Pathologica 2017 Mar;109(1):35-46

Department of Emergency and Organ Transplantation, Section of Pathological Anatomy, University of Bari Aldo Moro, Italy.

Objective: The aim of this retrospective study was to perform an epidemiological analysis of all odontogenic tumors treated in the University Hospitals "Ospedali Riuniti" in Ancona and "Policlinico" in Bari, from 1990 to 2015.

Materials And Methods: A retrospective survey of 277 patients treated for odontogenic tumors from 1990 to 2015 was performed. Data were retrieved from the archives of the above quoted Sections of Pathology. Read More

J Craniofac Surg 2017 Jul;28(5):1197-1205

*Department of Oral and Maxillofacial Surgery, Helsinki University Hospital †Department of Radiology, University of Helsinki and HUS Radiology (Medical Imaging Center), Helsinki, Finland.

Cysts and tumors are common lesions in the jaws. To be able to retain a good volume of the alveolar ridge during healing as well as strengthening the angle and body of the mandible and provide an instant improved support for adjacent teeth, reliable long-term bone regeneration is needed. The purpose of this prospective study was to promote bone regeneration by filling bony defects in the upper or lower jaw with granules of the bioactive glass S53P4 (BAG), which have osteostimulative and antimicrobial properties. Read More

J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):182

Department of Oral and Maxillofacial Surgery, Granada Virgen de las Nieves University Hospital, Granada, Spain.

Primary intraosseous odontogenic squamous cell carcinoma (PIOSCC) is a rare tumor. The incidence is low, and approximately 200 cases are reported in literature. The etiology is associated with the malignant degeneration of embryological remains. Read More

J Exp Ther Oncol 2017 May;12(1):35-42

Dept. of Oral and Maxillofacial Surgery, Rama Dental College Hospital and Research Centre, Kanpur-208024, Uttar Pradesh, India;

Background: The frequency and incidence of odontogenic cysts and tumors are controversial and depends in the geographic location. These lesions have great clinical and histopathological diversity, and reflect a need for epidemiological profile to be considered when these lesions are studied.

Aim: The purpose of this study was to determine the prevalence of odontogenic cysts and tumors over a period of 10 years and to compare with other data reported around the world. Read More

Cleft Palate Craniofac J 2017 05;54(3):338-342

Objective  To study the phenotype and overview the clinical management on Cleft Lip and/or Palate (CL/P) with Nevoid Basal Cell Carcinoma Syndrome (NBCCS) patients in Peking University School and Hospital of Stomatology. Design  Case series study. Main Outcome Measures  To describe the clinical phenotype of 12 CL/P with NBCCS patients who fulfilled the diagnostic criteria as well as to explore clinical management. Read More

Int Orthod 2017 Jun 29;15(2):238-250. Epub 2017 Apr 29.

Department of oral surgery, university of Toulouse, 31000 Toulouse, France.

Keratocysts, also known as keratocystic odontogenic tumors (KCOT), make up 7% of all odontogenic cysts and develop asymptomatically in most cases. Enucleation is the benchmark treatment. However, there are surgical alternatives. Read More

Ethiop J Health Sci 2016 Sep;26(5):491-496

Department of Dentistry, Oral and Maxillofacial Surgery case team, Millennium Medical College, St. Paul's hospital, Addis Ababa, Ethiopia.

Background: Keratocystic odontogenic tumor (KCOT) is a rare, benign, intraosseous tumor of odontogenic origin with a potential of aggressive and infiltrative behavior. It shows specific histopathological features, and has a high recurrence rate.

Case Details: The presented case was of a 30 years old man from South Ethiopia, with a giant keratocystic odontogenic tumor of the mandible. Read More

J Coll Physicians Surg Pak 2017 Jan;27(1):47-48

Department of Oral Pathology, SEGi University, Kota Damansara, Selangor, Malaysia.

Mandibular swellings may occur as a result of many benign lesions of odontogenic or non-odontogenic origin. Ameloblastomas are benign tumours of odontogenic origin, whose importance lies in its potential to grow into enormous size with resulting bone deformity, it is a slow-growing, persistent, and locally aggressive neoplasm. The unicystic ameloblastoma (UA) represents an ameloblastoma variant, presenting as a cyst clinically and radiographically, but showing typical ameloblastomatous epithelium lining histologically. Read More

Surg Pathol Clin 2017 Mar 29;10(1):177-222. Epub 2016 Dec 29.

Department of Surgical Science, East Carolina University School of Dental Medicine, 1851 MacGregor Downs Road, Greenville, NC 27834, USA.

This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma). Read More

J Clin Exp Dent 2017 Jan 1;9(1):e167-e171. Epub 2017 Jan 1.

Master's Degree in Oral Surgery - School of Dentistry - University of Seville.

The keratocystic odontogenic tumor is a benign odontogenic cystic neoplasia characterized by its thin, squamous epithelium with superficial parakeratosis. It has the potential for infiltration and local aggressiveness and has a high rate of recurrence. This neoplasia is predominantly found in males and people of white origin. Read More

J Craniomaxillofac Surg 2017 Feb 19;45(2):244-251. Epub 2016 Nov 19.

Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address:

Purpose: To investigate and compare the probability of recurrence of keratocystic odontogenic tumors (KCOTs) for different variables and treatment protocols.

Materials And Methods: An electronic search was undertaken in April 2016 that included clinical series of KCOTs reporting recurrences. Untransformed proportions and meta-analyses were performed to estimate the probability/risk of recurrence, according to several variables. Read More

J Craniomaxillofac Surg 2017 Jan 31;45(1):131-144. Epub 2016 Oct 31.

Department of Oral Medicine, Faculty of Dentistry, Thamar University, Thamar, Yemen.

Purpose: Among the different surgical treatments for keratocystic odontogenic tumors (KOTs), there is no single method associated with a zero recurrence rate (RR). Thus, this study aimed to seek the best surgical treatment with the least RR using a weighted event rated meta-analysis.

Materials And Methods: To address our study purpose, a systematic review and meta-analysis based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guideline was performed. Read More

Oral Maxillofac Surg 2017 Mar 21;21(1):21-26. Epub 2016 Nov 21.

Oral and Maxillofacial Surgeon of Ophir Loyola Hospital, Avenida Governador Magalhães Barata, 992, Belém, PA, 66063-240, Brazil.

Purpose: Keratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue. Thus, the aim of this study was to evaluate the outcome of enucleation followed by cryosurgery using a refrigerant spray of this gas mixture in ten patients diagnosed with KCOT. Read More

J Oral Maxillofac Surg 2017 Apr 26;75(4):750-758. Epub 2016 Oct 26.

Attending, Department of Oral and Maxillofacial Surgery, Mount Sinai Medical Center, New York, NY.

Ghost cell tumors are a family of lesions that range in presentation from cyst to solid neoplasm and in behavior from benign to locally aggressive or metastatic. All are characterized by the presence of ameloblastic epithelium, ghost cells, and calcifications. This report presents the cases of a 14-year-old girl with a calcifying cystic odontogenic tumor (CCOT) and a 65-year-old woman with a peripheral dentinogenic ghost cell tumor (DGCT) with dysplastic changes, a rare locally invasive tumor of odontogenic epithelium. Read More

J Korean Assoc Oral Maxillofac Surg 2016 Oct 25;42(5):284-287. Epub 2016 Oct 25.

Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Korea.

Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is characterized by various embryological deformities and carcinoma formation. It is caused by PTCHI gene mutations and is autosomal dominantly inherited. Some of the main symptoms of NBCCS are multiple basal cell carcinomas, multiple keratocystic odontogenic tumors (KCOTs) of the mandible, hyperkeratosis of the palmar and plantar, skeletal deformity, calcification of the falx cerebri, and facial defomity. Read More

BMC Res Notes 2016 Oct 18;9(1):469. Epub 2016 Oct 18.

Department of Pedodontics, University Dentistry Clinical Center of Kosova, Prishtina, Republic of Kosovo.

Background: Ameloblastoma is a benign epithelial odontogenic tumor. It is often aggressive and destructive, with the capacity to attain great size, erode bone and invade adjacent structures. Unicystic ameloblastoma is a rare odontogenic lesion, with clinical, radiographic and gross features of jaw cysts. Read More

Indian J Dent Res 2016 Jul-Aug;27(4):441-444

Department of Oral and Maxillofacial Pathology and Microbiology, D.Y. Patil University School of Dentistry, Sector 7, Navi Mumbai, Maharashtra, India.

The keratocystic odontogenic tumor (KCOT), formerly known as odontogenic keratocyst, is a benign developmental odontogenic tumor with many distinguishing clinical and histologic features. Hard tissue deposits, which usually take the form of dystrophic calcifications, cartilaginous tissue, or dentinoid, are uncommon findings in the connective tissue capsule of the KCOT. We report a case of a 33-year-old female with KCOT showing osseous tissue and calcified deposits close to its epithelial lining, which is an extremely rare occurrence. Read More

Kathmandu Univ Med J (KUMJ) 2016 Oct.-Dec.;14(56):370-372

Department of Oral and Maxillofacial Surgery, Pacific Dental College and Hospital, Debari. Udaipur, Rajasthan, Pin. - 313024.

The Keratocystic Odontogenic Tumor is a developmental cyst derived from the enamel organ or from the dental lamina. It is a benign, multicystic, intraosseous tumor of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium and has a potential for aggressive, infiltrative behavior and recurrence. Keratocystic Odontogenic Tumors have a predilection for males and occurs mainly in the second and third decade of life, most commonly in the mandible, mostly in the posterior body, the angle and the ascending ramus. Read More

Acta Odontol Scand 2016 Nov 27;74(8):591-597. Epub 2016 Sep 27.

b Department of Oral Surgery and Pathology , School of Dentistry, Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.

Purpose: To integrate the available data published on peripheral calcifying cystic odontogenic tumour (CCOT) and peripheral dentinogenic ghost cell tumour (DGCT) into a comprehensive analysis of its clinical and radiologic features.

Methods: An electronic search was undertaken in May, 2016. Eligibility criteria included publications reporting cases of peripheral CCOTs/DGCTs having enough clinical, radiological and histological information to confirm a definite diagnosis. Read More

Br J Oral Maxillofac Surg 2017 04 23;55(3):348-349. Epub 2016 Sep 23.

Consultant in OMFS, Northwick Park Hospital, Watford Road, Harrow, Middlesex, HA13UJ, United Kingdom.

J Clin Diagn Res 2016 Aug 1;10(8):ZD01-4. Epub 2016 Aug 1.

Postgraduate Student, Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth Deemed University Dental College and Hospital , Pune, Maharashtra, India .

Odontogenic Keratocyst (OKC) and Ameloblastomas are slow growing benign odontogenic lesions that primarily occur in the molar region of the mandible. Clinically and radiographically both ameloblastoma, especially the Unicystic ameloblastoma and OKC are indistinguishable due to the similar location of occurrence and the age of patients. It is very rare for these lesions to arise simultaneously in a patient's jaw. Read More