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Front Oncol 2021 18;11:781205. Epub 2021 Nov 18.

Section of Otorhinolaryngology - Head and Neck Surgery, Department of Neurosciences, University of Padua - "Azienda Ospedaliera di Padova", Padua, Italy.

Internal or common carotid artery encasement (CAE) is observed in almost 2-7% of head and neck cancers (HNC) and designates the tumor with the T4b category. This clinical scenario is associated with a dismal prognosis, owing to the risk for thrombosis and bleeding that usually characterizes such an advanced cancer. Standardized radiological criteria to infer invasion of the carotid artery are lacking. Read More

Orbit 2021 Jun 9:1-5. Epub 2021 Jun 9.

Discipline of Ophthalmology and Visual Sciences, The University of Adelaide, Adelaide, Australia.

Adenoid cystic carcinoma (AdCC) is a rare epithelial neoplasm of the head and neck, most commonly found in the salivary glands. Orbital AdCC is an uncommon clinical entity arising from the lacrimal glands, however primary orbital AdCC has been previously described in a small number of case reports. The exact origin of the neoplasm with uninvolved lacrimal gland in the orbit is unknown, however it may arise from ectopic lacrimal or salivary gland tissue, or extension from nearby epithelial structures. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Jan;56(1):11-17

Department of Otorhinolaryngology Head and Neck Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai 200031, China.

To evaluate the feasibility of the endoscopic transnasal approach (ETA) and to analyze the outcomes and factors of this surgical technique in the management of the tumor invading the anterior skull base. A retrospective analysis was performed on 42 patients (31 males and 11 females, with mean age of 49 years) with sinonasal tumor invading the anterior skull base, who underwent ETA from June 2015 to April 2019 in Eye, Ear, Nose and Throat Hospital of Fudan University. Pathologically, there were 15 cases of squamous carcinoma (14 patients with T4bN0M0 and 1 patient with T4bN1M0) and 27 of olfactory neuroblastomas with Kadish stage C. Read More

Otol Neurotol 2021 02;42(2):312-318

Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital of Modena, Modena.

Objective: The aim of this study was to report a multicentric surgical experience in the exclusive endoscopic management of glomus tympanicum (GT).

Study Design: Retrospective case series review at two institutions.

Setting: Tertiary referral centers. Read More

Ann Thorac Surg 2021 08 27;112(2):501-509. Epub 2020 Oct 27.

Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.

Background: Management of type A aortic dissection with cerebral malperfusion poses a significant challenge. Although involvement of craniocervical vessels is undoubtedly critical, it is not well investigated in the surgical literature.

Methods: Between 1997 and 2019, 775 patients presented with acute type A aortic dissection and 80 (10%) with cerebral malperfusion. Read More

J Craniofac Surg 2020 Jul-Aug;31(5):e495-e497

Department of Surgery and Perioperative Care, Seton Institute of Reconstructive and Plastic Surgery, University of Texas at Austin, Austin, TX.

Background: Respiratory distress is a frequent occurrence in neonates, typically caused by a variety of pulmonary conditions. Accurate diagnosis of the cause is vital to appropriately treat neonates and prevent long-term complications. Neck masses rarely cause respiratory distress in this setting but should be considered when clinical signs indicate. Read More

J Neurooncol 2020 Dec 27;150(3):437-444. Epub 2020 Feb 27.

Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Introduction: Malignancies involving the temporal bone are increasingly common and require specialized multi-disciplinary care. Given this complex location, involvement of the lateral skull base and local neurovascular structures is common. In this review we discuss general principles for temporal bone resection, as well as alternative and complementary surgical approaches that should be considered in the management of patients with temporal bone cancer. Read More

J Med Case Rep 2019 Mar 10;13(1):73. Epub 2019 Mar 10.

Neonatal Intensive Care Unit, Ruth Rappaport Children's Hospital, Rambam Health Campus, Haifa, Israel.

Background: A giant congenital cervical teratoma is often highly vascularized; thus, in addition to a life-threatening airway occlusion at birth it comprises a high risk for significant and lethal blood loss during resection. In the case presented, an endovascular embolization of the carotid artery that supplied a giant congenital cervical teratoma was done as part of a three-stage treatment soon after birth and contributed to an overall good outcome. Embolization in cases of cervical teratomas was not described previously. Read More

J Vasc Surg 2019 01;69(1):181-189

Division of Vascular Surgery, Eastern Virginia Medical School, Norfolk, Va. Electronic address:

Objective: Head and neck cancer can involve the surrounding vasculature and require technically challenging vascular interventions. These interventions can be complicated by tumor invasion, history of prior surgery, and history of radiation therapy. Our aim was to examine patients with vascular interventions in association with head and neck cancer to determine outcomes and best practice. Read More

J Neurosurg Pediatr 2018 12;23(3):325-332

OBJECTIVE Carotid body tumors (CBTs), extraadrenal paragangliomas, are extremely rare neoplasms in children that often require multimodal surgical treatment, including preoperative anesthesia workup, embolization, and resection. With only a few cases reported in the pediatric literature, treatment paradigms and surgical morbidity are loosely defined, especially when carotid artery infiltration is noted. Here, the authors report two cases of pediatric CBT and provide the results of a systematic review of the literature. Read More

Ann Vasc Surg 2019 Apr 27;56:355.e11-355.e15. Epub 2018 Nov 27.

Department of Vascular Surgery, Singapore General Hospital, Singapore.

Background: Surgical management of advanced head and neck tumors involving the carotid artery remains controversial with compromised survival outcomes and heightened risks of morbidity and mortality.

Case: We describe a case of a 74-year-old lady with previous T1N0M0 left tongue squamous cell carcinoma, who developed a left nodal recurrence encasing the left external carotid artery from the carotid bifurcation. She underwent an extended left radical neck dissection with carotid artery patch plasty and remains well to date, 10 months after surgery. Read More

World Neurosurg 2019 Feb 22;122:e1491-e1504. Epub 2018 Nov 22.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

Background: Based on our experience with the endoscopic endonasal approach (EEA) and transorbital approach (TOA) for middle cranial fossa tumors, we evaluated the efficacy and limitations of visualization and the clinical outcomes associated with the approaches depending on the surgical corridors. In addition, we determined the optimal strategy for each approach.

Methods: Between September 2015 and May 2018, we retrospectively reviewed clinical outcomes in 21 patients who underwent minimally invasive endoscopic surgery for middle cranial fossa tumors involving the cavernous sinus. Read More

J Neurol Surg B Skull Base 2017 Apr 9;78(2):120-124. Epub 2016 Sep 9.

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.

 An ectopic pituitary adenoma presenting as a clival or sphenoid mass is a rare clinical occurrence that may mislead the clinician and result in unnecessary interventions or potential medicolegal consequences. Here, we present one of the largest multi-institutional case series and review the literature with an emphasis on radiological findings and critical preoperative workup.  Retrospective chart review. Read More

Dan Med J 2017 Mar;64(3)

PTA is a collection of pus located between the tonsillar capsule and the pharyngeal constrictor muscle. It is considered a complication of acute tonsillitis and is the most prevalent deep neck infection (approximately 2000 cases annually in Denmark) and cause of acute admission to Danish ENT departments. Teenagers and young adults are most commonly affected and males may predominate over females. Read More

J Neurol Surg B Skull Base 2017 Feb 20;78(1):52-58. Epub 2016 Jun 20.

Division of Head and Neck Surgery, Department of Oral and Maxillofacial Surgery, University of Florida College of Medicine, Jacksonville, Florida, United States; Division of Surgical Oncology, University of Florida College of Medicine, Jacksonville, Florida, United States.

 The objective of this study was to report the outcomes on a preliminary cohort of patients with tumor encasement of either, or both, the cervical internal carotid artery (ICA) and common carotid artery (CCA) following preoperative covered stent placement and surgical resection.  This study was set at the University of Florida College of Medicine, Jacksonville, FL.  Subjects who received preoperative stenting of the cervical ICA/CCA before surgical resection of head and neck tumors between April 1, 2015, and July 31, 2015 were participated. Read More

Otolaryngol Clin North Am 2016 Jun;49(3):777-90

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

The most common vascular tumors encountered by the otolaryngologist are rare chromaffin cell tumors termed paragangliomas. Within the head and neck region, they commonly arise from the carotid body, vagus nerve (glomus vagale), and jugular vein (glomus jugulare). Other vascular head and neck tumors include sinonasal malignancies, because of proximity to or involvement of the pterygoid plexus as well as the rich vascularity of the sinonasal mucosa; juvenile nasopharyngeal angiofibroma, a vascular tumor of male adolescents; unusual vascular tumors such as hemangiopericytoma; and metastatic renal cell cancer, which has a proclivity for an unusually rich blood supply. Read More

J Vasc Surg 2016 Jun 28;63(6):1525-30. Epub 2016 Feb 28.

Department of Surgery, Division of Vascular Surgery, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, Pa.

Background: The purpose of this study was to examine outcomes of a patient cohort undergoing intervention for carotid blowout syndrome associated with head and neck cancer.

Methods: Patients with head and neck cancer who presented with carotid distribution bleeding from 2000 to 2014 were identified in the medical record. Primary outcomes were short- and midterm mortality and recurrent bleeding. Read More

J Laryngol Otol 2015 Dec 8;129(12):1148-55. Epub 2015 Oct 8.

Department of Otorhinolaryngology, Head & Neck Surgery,Memorial Ankara Hospital,Turkey.

Objective: The tumour-node-metastasis staging system has a dynamic structure that is continuously being updated as scientific data develops. This review discusses some suggested revisions on tumour-node-metastasis staging of human papillomavirus negative upper aerodigestive tract cancers.

Methods: The seventh edition of The American Joint Committee on Cancer Staging Manual was reviewed and important issues that could be considered for revision were identified and discussed. Read More

J Ultrasound 2015 Jun 5;18(2):197-200. Epub 2014 Dec 5.

Department of Pediatrics, McMaster Children's Hospital, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1 Canada.

A vein of Galen arteriovenous malformation (VGAM) is a rare intracranial shunt lacking a capillary bed and resulting in subsequent aneurysmal enlargement. VGAM has been previously reported to present as cardiovascular abnormalities, including increased right-sided cardiac load and pressure, cardiac dilatation, pulmonary hypertension and retrograde flow into the aortic arch. We report the first case of VGAM presenting as a gross right-sided neck swelling in a 39-week-old immediately at birth. Read More

Neurosurg Focus 2014 ;37(4):E13

Department of Neurosurgery-Head & Neck Surgery, Wexner Medical Center at The Ohio State University, Columbus, Ohio.

Object: Skull base chondrosarcomas are slow-growing, locally invasive tumors that arise from the petroclival synchondrosis. These characteristics allow them to erode the clivus and petrous bone and slowly compress the contents of the posterior fossa progressively until the patient becomes symptomatic, typically from cranial neuropathies. Given the site of their genesis, surrounded by the petrous apex and the clival recess, these tumors can project to the middle fossa, cervical area, and posteriorly, toward the cerebellopontine angle (CPA). Read More

Semin Intervent Radiol 2013 Sep;30(3):245-8

Division of Vascular and Interventional Radiology, Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.

Involvement of the carotid artery by malignant processes of the head and neck with compromise of vessel integrity and rupture-"carotid blowout syndrome" (CBS)-is one of the most devastating complications of malignancy. Most often, it is associated with squamous cell cancer and almost always in patients who have undergone prior radiation therapy. CBS is classified as threatened, impending, or acute. Read More

Stroke 2014 Jan 10;45(1):37-41. Epub 2013 Dec 10.

From the Department of Neurology, Dijon University Hospital, Dijon, France (Y.B., C.A.-E., M.G.); Department of Epidemiology and Public Health, Inserm U744, Pasteur Institute, Lille, France (S.D., J.D.); Department of Neurology, EA1046, Lille University Hospital, Lille, France (S.D., D.L.); Department of Clinical and Experimental Sciences, Neurology Clinic, Brescia University Hospital, Brescia, Italy (A.P.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T., T.M., A.M.); Department of Neurology, University Hospital of Basel, Basel, Switzerland (S.E., P.L.); Department of Neurology, University Hospital of Heidelberg, Heidelberg, Germany (C.G.-G., M.K.); Department of Neurology, Sainte-Anne University Hospital, Paris, France (E.T.); Department of Neurology, San Raffaele University Hospital, Milan, Italy (M.S.); Stroke Unit, Perugia University Hospital, Italy (V.C.); and Laboratory of Experimental Neurology, Université Libre de Bruxelles, Brussels, Belgium (M.P., S.A.).

Background And Purpose: Little is known about factors contributing to multiple rather than single cervical artery dissections (CeAD) and their associated prognosis.

Methods: We compared the baseline characteristics and short-term outcome of patients with multiple to single CeAD included in the multicenter Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study.

Results: Among the 983 patients with CeAD, 149 (15. Read More

AJNR Am J Neuroradiol 2014 Feb 17;35(2):360-6. Epub 2013 Oct 17.

From the Departments of Radiology and Research Institute of Radiology (L.-B.Z., H.B.S., S.P., D.-g.L., J.H.S., D.H.L., D.C.S.), University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea.

Background And Purpose: Life-threatening bleeding in the head and neck requires urgent management. This study evaluated the angiographic findings related to head and neck bleeding and presents endovascular management techniques.

Material And Methods: Sixty-one consecutive patients who presented with acute bleeding in the head and neck areas and subsequently underwent endovascular therapy between January 2002 and October 2012 were included in our study. Read More

Angiol Sosud Khir 2012 ;18(4):107-12

Presented in the article is a rare clinical case report concerning successful treatment of a female patient with vaginal paraganglioma of the neck - a tumour extending from the level of the trunk of the common carotid artery in cranial direction to the base of the skull. Mentioned are difficulties of carrying out an operational intervention requiring the use of certain surgical techniques. The tumour was removed as a single block with the involvement into the process of the major vessels of the neck and nervous formations. Read More

Int J Oral Maxillofac Surg 2013 Apr 21;42(4):440-5. Epub 2012 Dec 21.

Department of Head and Neck Surgery, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China.

The surgical management of advanced cervical metastases with carotid artery involvement in patients with primary squamous cell carcinoma of the head and neck can be difficult. The authors retrospectively reviewed 73 patients over a 15-year period comparing the outcomes of carotid artery resection versus peeling the tumour off the carotid artery. Based on these findings, the authors suggest that in the absence of carotid wall involvement, nodal metastatic tumour should be peeled off the carotid artery where possible. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2012 Mar;47(3):180-4

Department of Head and Neck Surgery, Hunan Province Tumor Hospital, Changsha 410013, China.

Objective: To investigate the surgical managements for residual or recurrent diseases in the neck after radiotherapy in nasopharyngeal carcinoma.

Methods: Seventy-eight cases of neck masses (39 cases for unilateral residual diseases, 9 for bilateral residual diseases and 30 for recurrent diseases) after radiotherapy in nasopharyngeal carcinoma who were treated surgically between January 1990 and December 2005 were retrospectively analyzed. There were 56 males and 22 females. Read More

J Trauma Acute Care Surg 2012 Jun;72(6):1601-10

Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan 48109, USA.

Background: Digital subtraction angiography (DSA) is the gold standard for radiographic diagnosis of blunt cerebrovascular injury (BCVI), but use of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) has increased dramatically in BCVI screening. This study explores the utility, effectiveness, and cost of noninvasive CTA and MRA screening for BCVI.

Methods: Medical records of 2,025 consecutive adults evaluated for acute blunt neck trauma and BCVI were reviewed retrospectively. Read More

Head Neck 2013 Apr 27;35(4):527-34. Epub 2012 Apr 27.

Department of Otolaryngology-Head & Neck Surgery, International Islamic University, Malaysia, Kuantan, Malaysia.

Background: The purpose of this study was to identify the factors that may influence the management outcome in patients with jugular paragangliomas.

Methods: The surgical records of 121 cases of jugular paraganglioma (Fisch classifications C and D) were reviewed.

Results: The average follow-up was 88 months. Read More

Laryngoscope 2012 Jul 23;122(7):1615-9. Epub 2012 Mar 23.

Department of Otolaryngology-Head and Neck Surgery Medical University of South Carolina, Charleston, South Carolina, USA.

Inverted (Schneiderian) papilloma (IP) is a benign but locally aggressive tumor that is typically located in the sinonasal tract. Middle ear involvement and intracranial extension are rare. We present a patient with a history of a completely resected right nasal cavity IP that returned 7 months later with hearing loss, bilateral aural fullness, and right-sided facial weakness. Read More

Otol Neurotol 2011 Jul;32(5):882-6

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati/Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45267-0528, USA.

Objectives: Determine the prevalence of carotid artery injury (CAI) in patients with basilar skull fractures and describe significant demographic and radiographic risk factors for CAI.

Study Design: From January 2004 to December 2008, medical records of 1,279 consecutive adult patients treated for basilar skull fractures at a tertiary care academic hospital were retrospectively reviewed. Diagnostic angiography was performed in 112 patients because of concern for CAI. Read More