30,312 results match your criteria Mammography in Breast Cancer


Frequency and diagnostic outcome of bilateral recall at screening mammography.

Int J Cancer 2020 Jul 4. Epub 2020 Jul 4.

Department of Radiology, Canisius Wilhelmina Hospital, SZ, Nijmegen, The Netherlands.

This study was performed to determine the frequency of recall for bilateral breast lesions at screening mammography and compare its outcome with respect to unilateral recall. We included 329132 screening mammograms (34889 initial screens and 294243 subsequent screens) from a Dutch screening mammography programme between January 2013 and January 2018. During 2-year follow-up, we collected radiological data, pathology reports and surgical reports of all recalled women. Read More

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http://dx.doi.org/10.1002/ijc.33187DOI Listing

Dynamic contrast-enhanced magnetic resonance imaging for risk-stratified screening in women with BRCA mutations or high familial risk for breast cancer: are we there yet?

Breast Cancer Res Treat 2020 Jul 3. Epub 2020 Jul 3.

Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

Purpose: Women at an elevated lifetime risk for breast cancer (BC), including carriers of pathogenic mutations in BC predisposition genes, are recommended intensified BC screening that includes annual mammography (MG) and annual breast MRI. Controversy exists regarding the clinical utility of MRI as a screening tool in high-risk women. This paper is intended to review recent advances and remaining areas of uncertainty in order to further facilitate the incorporation of breast MRI into an intensified BC screening protocol for women at high familial risk and BRCA carriers. Read More

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http://dx.doi.org/10.1007/s10549-020-05759-3DOI Listing

Is There Any Association Between Mammographic Features of Microcalcifications and Breast Cancer Subtypes in Ductal Carcinoma In Situ?

Acad Radiol 2020 Jun 30. Epub 2020 Jun 30.

Department of General Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.

Rationale And Objectives: To analyze the association between mammographic features of microcalcifications and histopathological prognostic factors based on estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2/neu) in ductal carcinoma in situ (DCIS).

Materials And Methods: We retrospectively determined 66 patients with microcalcification-associated pure DCIS. Distribution and morphological features of the microcalcifications were described using Breast Imaging Reporting and Data System lexicon. Read More

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http://dx.doi.org/10.1016/j.acra.2020.05.032DOI Listing

Sociodemographic factors and clinical presentation of women attending Cancer Detection Centre, Kolkata for breast examination.

J Clin Transl Res 2020 Apr 19;5(3):132-139. Epub 2020 Mar 19.

Department of Pathology and Cancer Screening, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.

Background: Breast cancer is the most common cancer in Indian women.

Aim: The aim of the study was to report the sociodemographic factors, habits, personal history, gynecological and obstetric history, the clinical presentation of Indian women, and analyze those factors with the diagnosis of breast cancer.

Methods: This study is based on retrospective data collection from case files of women who attended the Cancer Detection Centre during January1995-September 2016. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326264PMC

The technique and accuracy of breast specimen ultrasound in achieving clear margins in breast conserving surgery.

J Med Imaging Radiat Oncol 2020 Jul 1. Epub 2020 Jul 1.

School of Medicine, The University of Western Australia, Perth, Western Australia, Australia.

Introduction: The aim of this prospective study was to determine whether breast specimen ultrasound (SUS) can reliably be used to confirm whether ultrasound (US) visible breast malignancies are excised with clear margins during breast-conserving surgery (BCS), in order to avoid a second operation and recurrence.

Methods: A total of 95 consecutive participants with US visible malignancies, undergoing BCS, had the excised breast specimen transported to the radiology department intraoperatively. Breast SUS was used to confirm the presence of the lesion and measure the medial, lateral, superior and inferior margins. Read More

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http://dx.doi.org/10.1111/1754-9485.13077DOI Listing

Staying abreast of imaging - Current status of breast cancer detection in high density breast.

Radiography (Lond) 2020 Jun 28. Epub 2020 Jun 28.

Diagnostic Radiology Department, American University of Beirut Medical Center, P.O.Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon. Electronic address:

Objectives: The aim of this paper is to illustrate the current status of imaging in high breast density as we enter a new decade of advancing medicine and technology to diagnose breast lesions.

Key Findings: Early detection of breast cancer has become the chief focus of research from governments to individuals. However, with varying breast densities across the globe, the explosion of breast density information related to imaging, phenotypes, diet, computer aided diagnosis and artificial intelligence has witnessed a dramatic shift in new screening recommendations in mammography, physical examination, screening younger women and women with comorbid conditions, screening women at high risk, and new screening technologies. Read More

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http://dx.doi.org/10.1016/j.radi.2020.06.003DOI Listing

Unusual case of Paget disease of the nipple diagnosed by nipple scraping cytology.

Dermatol Online J 2020 Mar 15;26(3). Epub 2020 Mar 15.

Department of Pathology, Englewood Hospital and Medical Center, Englewood, NJ.

Paget disease of the nipple is a rare presentation of breast cancer. It is sometimes mistaken for a benign skin condition of the nipple and surrounding areola, which can significantly delay the diagnosis and treatment. In over 90% of cases there is an underlying carcinoma, either ductal carcinoma in situ (DCIS) or invasive breast cancer. Read More

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Breast cancer survivors' risk of interval cancers and false positive results in organized mammography screening.

Cancer Med 2020 Jun 30. Epub 2020 Jun 30.

Department of Public Health Programmes, Regional Hospital Randers, Randers, Denmark.

Background: Breast cancer survivors are increasing followed for new breast cancers / recurrences by mammography screening only. We aimed at assessing how often breast cancer survivors get a false positive or false negative result at mammography screening.

Methods: All mammography screenings performed between 2007 and 2017 in the Danish national mammography screening programme were included. Read More

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http://dx.doi.org/10.1002/cam4.3182DOI Listing

Deep Learning Pre-training Strategy for Mammogram Image Classification: an Evaluation Study.

J Digit Imaging 2020 Jun 30. Epub 2020 Jun 30.

Department of Biomedical Informatics, University of Pittsburgh, 3240 Craft Place, Pittsburgh, PA, 15213, USA.

In this work, we assess how pre-training strategy affects deep learning performance for the task of distinguishing false-recall from malignancy and normal (benign) findings in digital mammography images. A cohort of 1303 breast cancer screening patients (4935 digital mammogram images in total) was retrospectively analyzed as the target dataset for this study. We assessed six different convolutional neural network model structures utilizing four different imaging datasets (total > 1. Read More

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http://dx.doi.org/10.1007/s10278-020-00369-3DOI Listing

Radiomics nomogram of contrast-enhanced spectral mammography for prediction of axillary lymph node metastasis in breast cancer: a multicenter study.

Eur Radiol 2020 Jun 30. Epub 2020 Jun 30.

Department of Radiology, Yantai Yuhuangding Hospital, The Affiliated Hospital of Qingdao University, No. 20 Yuhuangding East Street, Yantai, 264000, Shandong, People's Republic of China.

Objective: This study aims to establish and validate a radiomics nomogram based on contrast-enhanced spectral mammography (CESM) for prediction of axillary lymph node (ALN) metastasis in breast cancer.

Methods: This retrospective study included 394 patients with breast cancer who underwent CESM examination in two hospitals. The least absolute shrinkage and selection operator (LASSO) logistic regression was established for feature selection and utilized to construct radiomics signature. Read More

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http://dx.doi.org/10.1007/s00330-020-07016-zDOI Listing

Proteomics of Sentinel Lymph Nodes in Early Breast Cancer for Identification of Thymidylate Synthase as a Potential Biomarker to Flag Metastasis: A Preliminary Study.

Cancer Manag Res 2020 23;12:4841-4854. Epub 2020 Jun 23.

Department of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.

Introduction: Breast cancer is the second most common cancer in women across the world. Some of the patients who present in the early stage of disease are affected by metastasis to the axillary group of lymph nodes. The first among this group that is affected is called as sentinel lymph node, and its diagnosis is crucial for the staging of cancer thereby dictating the type of surgical therapy. Read More

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http://dx.doi.org/10.2147/CMAR.S255684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320752PMC

Comparison of Mortality Among Participants of Women's Health Initiative Trials With Screening-Detected Breast Cancers vs Interval Breast Cancers.

JAMA Netw Open 2020 Jun 1;3(6):e207227. Epub 2020 Jun 1.

Knight Cancer Institute, Oregon Health & Science University, Portland.

Importance: Interval breast cancers (IBCs) are cancers that emerge after a mammogram with negative results but before the patient's next scheduled screening. Interval breast cancer has a worse prognosis than cancers detected by screening; however, it is unknown whether the length of the interscreening period is associated with prognostic features and mortality.

Objective: To compare the prognostic features and mortality rate of women with IBCs diagnosed within 1 year or between 1 and 2. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.7227DOI Listing

Organization Communication Factors and Abnormal Mammogram Follow-up: a Qualitative Study Among Ethnically Diverse Women Across Three Healthcare Systems.

J Gen Intern Med 2020 Jun 29. Epub 2020 Jun 29.

Department of Public Health, School of Social Sciences, Humanities, and Arts, University of California , Merced, CA, USA.

Background: Regular mammogram screening for eligible average risk women has been associated with early detection and reduction of cancer morbidity and mortality. Delayed follow-up and resolution of abnormal mammograms limit early detection efforts and can cause psychological distress and anxiety.

Objective: The goal of this study was to gain insight from women's narratives into how organizational factors related to communication and coordination of care facilitate or hinder timely follow-up for abnormal mammogram results. Read More

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http://dx.doi.org/10.1007/s11606-020-05972-2DOI Listing

Dose reduction in mammography by using imaging plate technology: A retrospective analysis.

Eur J Radiol 2020 Jun 19;129:109140. Epub 2020 Jun 19.

Universitätsklinikum Augsburg, Klinik für Diagnostische Radiologie und Neuroradiologie, Stenglinstr. 2, 86156, Augsburg, Deutschland.

Purpose: Conventional mammography is a decisive tool in detecting breast cancer. Continuous efforts are undertaken in order to further improve the image quality as well as to reduce the applied doses. The purpose of our study was to compare diagnostic image quality of dose reduced computed mammography with a new needle-based detector system to full dose powder imaging plates. Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.109140DOI Listing

Ductal carcinoma in situ on digital mammography versus digital breast tomosynthesis: rates and predictors of pathologic upgrade.

Eur Radiol 2020 Jun 26. Epub 2020 Jun 26.

Department of Radiology, Division of Breast Imaging, Massachusetts General Hospital, 55 Fruit Street, WAC 240, Boston, MA, 02114, USA.

Objectives: To compare upgrade rates of ductal carcinoma in situ (DCIS) on digital mammography (DM) versus digital breast tomosynthesis (DBT) and identify patient, imaging, and pathological features associated with upgrade risk.

Methods: A retrospective review was performed of 318 women (mean 59 years, range 37-89) with screening-detected DCIS from 2007 to 2011 (DM group) and from 2013 to 2016 (DBT group). Comparisons made between DM and DBT groups using the unpaired t test and chi-square test include detection rates of DCIS, upgrade rates to invasive cancer, and pathological features of DCIS and upgraded cases. Read More

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http://dx.doi.org/10.1007/s00330-020-07021-2DOI Listing

Flexible ultrasonic array for breast-cancer diagnosis based on a self-shape-estimation algorithm.

Ultrasonics 2020 Jun 17;108:106199. Epub 2020 Jun 17.

Key Lab of Nondestructive Testing, Ministry of Education, Nanchang Hangkong University, Nanchang 330063, China.

Breast cancer is a very common malignant tumour that typically occurs in women aged 35-70 years (accounting for 85% of patients). Recently, it has been appearing in younger women as well. Traditional ultrasonic transducers usually use a fixed array, which avoids the radiation from mammography, has a low cost, and can be used for repeated testing. Read More

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http://dx.doi.org/10.1016/j.ultras.2020.106199DOI Listing

Patient Delay in Breast Cancer Diagnosis in Two Hospitals in Karachi, Pakistan: Preventive and Life-Saving Measures Needed.

JCO Glob Oncol 2020 Jun;6:873-883

Adelaide Medical School, University of Adelaide, Adelaide, Australia.

Purpose: Patients with breast cancer in Pakistan commonly present with advanced disease. The objectives of this study were to evaluate the frequency and length of delays in seeking medical consultation and to assess the factors associated with them.

Methods: Four hundred ninety-nine patients with newly diagnosed breast cancer were enrolled and interviewed over the period from February 2015 to August 2017. Read More

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http://dx.doi.org/10.1200/GO.20.00034DOI Listing

The implications of increased mammographic breast density for breast screening in Jordan.

J Med Radiat Sci 2020 Jun 23. Epub 2020 Jun 23.

Faculty of Health Sciences, The University of Sydney, Sydney, NSW, Australia.

Introduction: Mammographic breast density is associated with a four to six times increased risk for breast cancer. Mammographic breast density varies by ethnicity, geographical region and age. The aim of this study was to document for the first time the mammographic breast density of Jordanian women and to explore its relationship with age. Read More

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http://dx.doi.org/10.1002/jmrs.414DOI Listing

Biennial screening mammography: How many women ask for more? Estimate of the interval mammogram rate in an organised population-based screening programme.

Radiol Med 2020 Jun 23. Epub 2020 Jun 23.

Unit of Radiology, IRCCS Policlinico San Donato, Via Morandi 30, San Donato Milanese, 20097, Milan, Italy.

Objectives: To estimate the interval mammogram rate, i.e. the undertaking of an additional mammography between scheduled screening rounds, and identify factors influencing this phenomenon. Read More

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http://dx.doi.org/10.1007/s11547-020-01238-3DOI Listing

A Cross-Sectional Observational Study to Compare the Role of Ultrasound with Mammography in Women Identified at High Risk for Breast Cancer in a Population in China.

Med Sci Monit 2020 Jun 24;26:e919777. Epub 2020 Jun 24.

Medical Ultrasound Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China (mainland).

BACKGROUND Currently, there is no national breast cancer screening program in China. In countries that have screening programs, screening mammography is used. This study aimed to compare the imaging parameters and diagnostic findings between ultrasound and mammography in women at high risk who had a histologically confirmed diagnosis of breast cancer in a population in China. Read More

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http://dx.doi.org/10.12659/MSM.919777DOI Listing

Mammographic Breast Density and Urbanization: Interactions with BMI, Environmental, Lifestyle, and Other Patient Factors.

Diagnostics (Basel) 2020 Jun 20;10(6). Epub 2020 Jun 20.

Department of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Mammographic breast density (MBD) is an important imaging biomarker of breast cancer risk, but it has been suggested that increased MBD is not a genuine finding once corrected for age and body mass index (BMI). This study examined the association of various factors, including both residing in and working in the urban setting, with MBD. Questionnaires were completed by 1144 women attending for mammography at the London Breast Institute in 2012-2013. Read More

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http://dx.doi.org/10.3390/diagnostics10060418DOI Listing

Relaxation-compensated CEST (chemical exchange saturation transfer) imaging in breast cancer diagnostics at 7T.

Eur J Radiol 2020 May 24;129:109068. Epub 2020 May 24.

Division of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

Purpose: To investigate whether fat-corrected and relaxation-compensated amide proton transfer (APT) and guanidyl CEST-MRI enables the detection of signal intensity differences between breast tumors and normal-appearing fibroglandular tissue in patients with newly-diagnosed breast cancer.

Method: Ten patients with newly-diagnosed breast cancer and seven healthy volunteers were included in this prospective IRB-approved study. CEST-MRI was performed on a 7 T-whole-body scanner followed by a multi-Lorentzian fit analysis. Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.109068DOI Listing

The diagnostic performance of CESM and CE-MRI in evaluating the pathological response to neoadjuvant therapy in breast cancer: a systematic review and meta-analysis.

Br J Radiol 2020 Jul 2:20200301. Epub 2020 Jul 2.

Department of Radiology, The Yongchuan Affiliated Hospital, Chongqing Medical University, Yongchuan District, Chongqing, PR China.

Objectives: Neoadjuvant chemotherapy (NAC) is an important method for breast cancer treatment. By monitoring its pathological response, the selection of clinical treatment strategies can be guided. In this study, the meta-analysis was used to compare the accuracy of contrast-enhanced MRI (CE-MRI) and contrast-enhanced spectral mammography (CESM) in detecting the pathological response of NAC. Read More

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http://dx.doi.org/10.1259/bjr.20200301DOI Listing

Impact of Full-Field Digital Mammography versus Film-Screen Mammography in Population Screening: a Meta-analysis.

J Natl Cancer Inst 2020 Jun 23. Epub 2020 Jun 23.

School of Public Health, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia.

Background: Breast screening programs replaced film mammography with digital mammography, the effects of this practice shift in population screening on health outcomes can be measured through examination of cancer detection and interval cancer rates.

Methods: A systematic review and random effects meta-analysis were undertaken. Seven databases were searched for publications that compared film to digital mammography within the same population of asymptomatic women and reported cancer detection and/or interval cancer rates. Read More

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http://dx.doi.org/10.1093/jnci/djaa080DOI Listing

Imaging of male breast disease: the good, the bad and the ugly - A pictorial review.

Clin Imaging 2020 Jun 17;68:45-56. Epub 2020 Jun 17.

Grupo Fleury, São Paulo, Brazil; Hospital São Paulo, Universidade Federal de São Paulo, São Paulo, Brazil.

The male breast is affected by a broad spectrum of conditions, ranging from benign to malignant, many of which are similar to those occurring in its female counterpart. Despite the challenge motivated by different imaging characteristic features, correct imaging interpretation in male breast disease may aid at differentiation between benign and suspected conditions, narrow the differential diagnosis and guide subsequent management. The purpose of this review is to showcase a wide array of male breast diseases, discuss their imaging presentations and key features for diagnosis. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.06.025DOI Listing

Full-field digital mammography: the '30% rule' and influences on visualisation of the pectoralis major muscle on the craniocaudal view of the breast.

J Med Radiat Sci 2020 Jun 22. Epub 2020 Jun 22.

Faculty of Science, School of Dentistry & Health Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.

Introduction: To investigate compliance to the '30% rule' and key factors which may influence visualisation of the pectoralis major muscle (PMM) on the craniocaudal (CC) view of the breast.

Methods: A retrospective review of 2688 paired full-field digital mammography (FFDM) CC view mammograms of women attending BreastScreen NSW between August and October 2015 was undertaken. PMM visualisation and measurements of PMM width and length, compressed breast thickness, the posterior nipple line (PNL) and age were recorded. Read More

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http://dx.doi.org/10.1002/jmrs.404DOI Listing

Açaí ( Mart) Consumption and Prevention of Chronic Diseases: Is There an Association? A Preliminary Study.

ScientificWorldJournal 2020 1;2020:5782485. Epub 2020 Jun 1.

Pathology Department, Post-Graduate Program in Adult Health, Federal University of Maranha˜o, Sa˜o Luís, Maranha˜o, Brazil.

Background: Flavonoids from a variety of fruits, including açaí, have beneficial antioxidant activity in several diseases, including cancer. Breast cancer is the second most prevalent cancer among Brazilian women. Studies have shown the action of flavonoids on neoplastic cells, as well as on diabetes and neurodegenerative and cardiovascular diseases. Read More

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http://dx.doi.org/10.1155/2020/5782485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285393PMC

Long-term Incidence and Mortality Trends for Breast Cancer in Germany.

Geburtshilfe Frauenheilkd 2020 Jun 17;80(6):611-618. Epub 2020 Jun 17.

German Centre for Cancer Registry Data (ZfKD), Robert Koch Institute, Berlin, Germany.

Changes in risk factors and the introduction of mammography screening in 2005 have led to dramatic changes in the breast cancer-associated burden of disease in Germany. This study aimed to investigate long-term disease-related incidence and mortality trends in women from East and West Germany since the reunification of Germany. Total and stage-specific incidence rates were evaluated based on data obtained from selected cancer registries. Read More

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http://dx.doi.org/10.1055/a-1160-5569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299687PMC

Machine learning-based lifetime breast cancer risk reclassification compared with the BOADICEA model: impact on screening recommendations.

Br J Cancer 2020 Jun 22. Epub 2020 Jun 22.

Department of Clinical Research, Faculty of Medicine, University of Basel, Basel, Switzerland.

Background: The clinical utility of machine-learning (ML) algorithms for breast cancer risk prediction and screening practices is unknown. We compared classification of lifetime breast cancer risk based on ML and the BOADICEA model. We explored the differences in risk classification and their clinical impact on screening practices. Read More

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http://dx.doi.org/10.1038/s41416-020-0937-0DOI Listing

[Results of the breast cancer population screening circuit at the San Carlos Clinical Hospital.]

Rev Esp Salud Publica 2020 Jun 22;94. Epub 2020 Jun 22.

Departamento de Ginecología y Obstetricia. Unidad de Patología Mamaria. Instituto de Salud de la Mujer José Botella Llusía. Hospital Clínico San Carlos. Madrid. España.

Objective: The objective of the study was to compare the time difference between diagnose and treatment with relation to switching protocols in screening program, DEPRECAM; and to analyze the screening program over our sample.

Methods: It is a retrospective study involving 173 patients with two no time concurrent clinical cohorts referred from DEPRECAM program to San Carlos Clinic Hospital (HCSC) between March 2017 and January 2019. It was compared the time differences between the group forwarded to Breast Pathology service (Group A; n=92) and the group directly forwarded to Radiology department (Group B; n=81), using the non-parametric Mann-Whitney U test, estimating the difference of the means together with its 95% confidence interval. Read More

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Mammographic density changes during neoadjuvant breast cancer treatment: NeoDense, a prospective study in Sweden.

Breast 2020 Jun 4;53:33-41. Epub 2020 Jun 4.

Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark. Electronic address:

Objectives: To assess if mammographic density (MD) changes during neoadjuvant breast cancer treatment and is predictive of a pathological complete response (pCR).

Methods: We prospectively included 200 breast cancer patients assigned to neoadjuvant chemotherapy (NACT) in the NeoDense study (2014-2019). Raw data mammograms were used to assess MD with a fully automated volumetric method and radiologists categorized MD using the Breast Imaging-Reporting and Data System (BI-RADS), 5th Edition. Read More

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http://dx.doi.org/10.1016/j.breast.2020.05.013DOI Listing

Breast cancer in transgender women: A case report.

Clin Imaging 2020 May 15;68:20-23. Epub 2020 May 15.

Department of Radiology, University of Illinois Hospital and Health Sciences System, 1740 W Taylor St, Chicago, IL 60612, USA. Electronic address:

The risk of breast cancer in transgender women continues to be a topic of debate in the medical literature. Studies have theorized an increased risk in transgender women taking feminizing hormone therapy on the basis of established risk factors and histological characteristics in cisgender men and established increased risk in cisgender women on hormone replacement therapy. Historically, testing this theory has been challenging due to a relative lack of cases and large-scale, long-term studies reported in the literature. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.05.006DOI Listing

Correlation between imaging features and molecular subtypes of breast cancer in young women (≤30 years old).

Jpn J Radiol 2020 Jun 19. Epub 2020 Jun 19.

Department of Breast Radiology, Affiliated Hospital of Qingdao University, Qingdao University, No. 16, Jiangsu Road, Qingdao, 266100, Shandong Province, China.

Objectives: To analyze the features of digital mammography (DM) plus digital breast tomosynthesis (DBT), ultrasonography (US) and magnetic resonance imaging (MRI) of breast cancer in young women (≤30 years old) and the correlation with molecular subtypes.

Materials And Methods: We performed a retrospective study of imaging features of consecutive young women aged ≤30 years who were treated and surgically confirmed with breast cancer between January 2013 and December 2019 in our institution. All patients were Chinese women. Read More

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http://dx.doi.org/10.1007/s11604-020-01001-8DOI Listing

Invasive solid papillary carcinoma with neuroendocrine differentiation of the breast: a case report and literature review.

Surg Case Rep 2020 Jun 19;6(1):143. Epub 2020 Jun 19.

Department of Breast Surgery, Kyoto University Hospital, 54 Kawaharacho, Syogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Background: Solid papillary carcinoma (SPC) of the breast is a rare breast cancer that accounts for less than 1% of all breast cancers. The optimal clinical management of SPC remains controversial. Here, we report a case of invasive SPC with neuroendocrine differentiation in addition to review of the current literature. Read More

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http://dx.doi.org/10.1186/s40792-020-00905-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305294PMC

Quantitative Analysis of Enhancement Intensity and Patterns on Contrast-enhanced Spectral Mammography.

Sci Rep 2020 Jun 17;10(1):9807. Epub 2020 Jun 17.

Department of Radiology, Sichuan University West China Hospital, No. 37 Guoxue Alley, Chengdu, 610041, Sichuan Province, China.

CESM is an emerging digital mammography technology with a high breast cancer detection and a limited diagnostic specificity. In order to improve specificity, we quantitatively assessed enhancement intensity of breast lesions with different pathological types and hormonal receptor status and evaluated the consistency of enhancement patterns between CESM and DCE-MRI. A total of 145 lesions were enrolled, consisting of 43 malignant (17 non-infiltrating cancers and 26 infiltrating cancers) and 99 benign lesions. Read More

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http://dx.doi.org/10.1038/s41598-020-66501-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299980PMC

Automated breast ultrasound compared to hand-held ultrasound in surveillance after breast-conserving surgery.

Tumori 2020 Jun 18:300891620930278. Epub 2020 Jun 18.

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Italy.

Purpose: To investigate the agreement between automated breast ultrasound (ABUS) and hand-held ultrasound (HHUS) in surveillance of women with a history of breast cancer in terms of recurrences or new ipsilateral or contralateral breast cancer.

Methods: The institutional review board approved this retrospective study and informed consent was waived. From April to June 2016, women with dense breasts undergoing annual surveillance with mammography and HHUS after breast-conserving surgery were offered supplemental ABUS (Invenia). Read More

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http://dx.doi.org/10.1177/0300891620930278DOI Listing

Molecular Breast Imaging in Clinical Practice.

AJR Am J Roentgenol 2020 Jun 17:1-8. Epub 2020 Jun 17.

Department of Radiology, Mayo Clinic, Rochester, MN.

The purpose of this article is to review clinical uses and image interpretation of molecular breast imaging (MBI) and clarify radiation risks. MBI detects additional cancers compared with conventional imaging in women with dense breasts and those with elevated risk of breast cancer. Its role as an imaging biomarker of cancer risk and in assessing neoadjuvant chemotherapy response is growing. Read More

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http://dx.doi.org/10.2214/AJR.19.22622DOI Listing

Value of tomography in detecting breast masses and discriminating malign and benign lesions.

Turk J Surg 2019 Dec 16;35(4):265-272. Epub 2019 Dec 16.

Karadeniz Teknik Üniversitesi Tıp Fakültesi, Radyoloji Anabilim Dalı, Trabzon, Türkiye.

Objectives: The main purpose of the present study was to determine the effectivity of computerized tomography (CT) in detecting breast masses and discriminating masses as malignant or benign.

Material And Methods: After having received the institutional local ethics committee approval, an experienced radiologist who did not participate in the study created a patient pool by searching our health center's Pathology department database between 2010 and 2018. The group created consisted of dense and non-dense breast types equally and included approximately similar percentages of benign and malignant breast mass sizes. Read More

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http://dx.doi.org/10.5578/turkjsurg.4258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282456PMC
December 2019

Tattoo pigment mimicking axillary lymph node calcifications on mammography.

Radiol Case Rep 2020 Aug 9;15(8):1194-1196. Epub 2020 Jun 9.

Duke University Medical Center Department of Radiology, NC, USA.

Axillary lymph nodes can appear abnormal on mammography due to uptake of tattoo pigment and a malignant cause must be excluded through diagnostic workup. Furthermore, tattoo pigment can mimic malignant pathology at surgery or confound appropriate staging of breast cancer. We present the case of a 47-year-old female with left axillary lymph nodes demonstrating new coarse densities suspicious for malignant calcifications on screening mammogram. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292895PMC

Comparative analysis of the access to health-care services and breast cancer therapy in 10 Eastern European countries.

SAGE Open Med 2020 20;8:2050312120922029. Epub 2020 May 20.

University of Applied Health Sciences, Zagreb, Croatia.

Aim: The aim of this study is to compare the differences in breast cancer therapy, health-care service practices, and their availability in ten European countries-Albania, Bosnia and Herzegovina, Bulgaria, Kosovo, Montenegro, Republic of North Macedonia, Croatia, Romania, Slovenia, and Republic of Serbia.

Methods: An inquire survey was conducted among oncologists in the participating countries. The questionnaire was of qualitative character and focused on several key areas as screening practices, diagnosing, treatment, and health-care procedures utilization. Read More

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http://dx.doi.org/10.1177/2050312120922029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249592PMC

Morbidity as a Predictor for Participation in the Danish National Mammography Screening Program: A Cross-Sectional Study.

Clin Epidemiol 2020 25;12:509-518. Epub 2020 May 25.

Department of Clinical Epidemiology, Aarhus University Hospital,Aarhus N 8200, Denmark.

Purpose: In this cross-sectional study, we evaluated the association between morbidity and participation in the prevalence round of the Danish national mammography screening program.

Patients And Methods: Morbidity was assessed by the Charlson Comorbidity Index (CCI) score (0, 1-2, and ≥3) and by 19 individual diagnoses. We retrieved data on participation from The Danish Quality Database of Mammography Screening and on diagnoses from The Danish National Patient Registry. Read More

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http://dx.doi.org/10.2147/CLEP.S250418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259444PMC

Diagnostic Value of Elastography, Strain Ratio, and Elasticity to B-Mode Ratio and Color Doppler Ultrasonography in Breast Lesions.

Int J Gen Med 2020 25;13:215-224. Epub 2020 May 25.

Social Determinant of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Purpose: The aim of this study was to investigate the sensitivity, specificity, and diagnostic accuracy of sonoelastography (SE), strain ratio (SR), elasticity to B-mode (E/B) ratio, and color Doppler ultrasonography (US) in suspected breast lesions.

Materials And Methods: This prospective study was conducted on women referred to Alzahra university hospital of Tabriz for annual screening of breast cancer between May 2017 and December 2018. B-mode US, SE, and color Doppler imaging were conducted in females with suspected mammography reports. Read More

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http://dx.doi.org/10.2147/IJGM.S247980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259450PMC

Primary Care Providers Underutilize Breast Screening MRI for High-Risk Women.

Curr Probl Diagn Radiol 2020 May 17. Epub 2020 May 17.

University of Massachusetts Medical School, Worcester, MA.

Objective: Supplemental MRI screening for women at high risk for breast cancer is underutilized. Our study assessed how primary care providers in our healthcare network identify high-risk women and recommend high-risk screening breast MRI.

Methods: An electronic survey was distributed to providers in OB/GYN, family, and internal medicine departments between 1/14/19 and 3/22/19. Read More

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http://dx.doi.org/10.1067/j.cpradiol.2020.04.008DOI Listing

Breast Cancer Screening Behaviors in Women Aged 40 Years and Over in a Semi-Urban Region in Turkey: Relationships with Health Beliefs.

Healthcare (Basel) 2020 Jun 13;8(2). Epub 2020 Jun 13.

Department of Health Management, Kırklareli University School of Health, 39000 Kırklareli, Turkey.

In this study, we aimed to determine the breast cancer screening behavior of women and to investigate the relationship between health beliefs and screening behaviors. The study was cross-sectional. It was conducted between April 2017 and June 2017 with 416 women aged ≥40. Read More

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http://dx.doi.org/10.3390/healthcare8020171DOI Listing

Geographic Inequalities in Breast Cancer in Italy: Trend Analysis of Mortality and Risk Factors.

Int J Environ Res Public Health 2020 Jun 11;17(11). Epub 2020 Jun 11.

National Institute for Health, Migration and Poverty (INMP), Via di San Gallicano, 25/a, 00153 Rome, Italy.

We calculated time trends of standardised mortality rates and risk factors for breast cancer (BC) from 1990 to 2016 for all women resident in Italy. The age-standardised mortality rate in Italy decreased from 4.2 in 1990 to 3. Read More

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http://dx.doi.org/10.3390/ijerph17114165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312287PMC

Can Magnetic Resonance Imaging Replace Mammography and Ultrasonography for the Detection of Breast Lesions?

Cureus 2020 May 13;12(5):e8087. Epub 2020 May 13.

General Surgery, İzmir Katip Celebi University, Atatürk Training and Research Hospital, İzmir, TUR.

Objective We aimed to evaluate the role of magnetic resonance imaging (MRI) in the visualization of breast lesions and to estimate whether MRI can be a reliable alternative to mammography (MG) and ultrasonography (USG) for this purpose. Materials and methods In this retrospective, single-center study, an analysis of medical files of 260 patients with breast masses as breast imaging reports and data system (BI-RADS) 4 and 5 at MRI was performed. The features of the breast lump, such as the side, location, multi foci or multicentricity, histopathological diagnosis, contrast-enhancement characteristics, radiological, and pathological axillary involvement, were noted. Read More

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http://dx.doi.org/10.7759/cureus.8087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292694PMC

Standardizing mammogram screening in primary care: Integrating an evidence-based approach.

J Am Assoc Nurse Pract 2020 Jun 9. Epub 2020 Jun 9.

School of Nursing and Health Professions, University of San Francisco, San Francisco, California.

Background: Mammogram screening for surveillance and detection of breast cancer has been long recognized as a preventive health measure in primary care for women. However, a clear consensus on when to start screening individual women, based on age and risk factors, lacks guidance. Reputable organizations uphold varying breast cancer screening (BCS) guidelines for women potentiating the risk for fragmented and inconsistent practices among health care providers (HCPs). Read More

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http://dx.doi.org/10.1097/JXX.0000000000000418DOI Listing

Diagnostic accuracy of contrast-enhanced spectral mammography for breast lesions: A systematic review and meta-analysis.

Breast 2020 Jun 10;53:8-17. Epub 2020 Jun 10.

Department of Medicine and Surgery, University of Insubria, Como, Italy. Electronic address:

Breast cancer diagnosis and staging is based on mammography, ultrasound, and magnetic resonance imaging (MRI). Contrast enhanced spectral mammography (CESM) has gained momentum as an innovative and clinically useful method for breast assessment. CESM is based on abnormal enhancement of neoplastic tissue compared to surrounding breast tissue. Read More

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http://dx.doi.org/10.1016/j.breast.2020.06.005DOI Listing

The association of chronic diseases and mammography among Medicare beneficiaries living in Appalachia.

Womens Health (Lond) 2020 Jan-Dec;16:1745506520933020

Smart State Center for Heathcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Objective: This study assessed the relationship between presence and number of chronic disease and reception of mammogram in women 65 years and older, and how this relationship is influenced by primary care provider visits.

Methods: A total of 3306 women diagnosed with breast cancer from 2006 to 2008 from cancer registries in four Appalachian states were analyzed.

Results: Having a mammogram within the past 2 years was associated with having at least one chronic disease. Read More

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http://dx.doi.org/10.1177/1745506520933020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297020PMC

Review of Nonmammary Metastases to the Breast: Imaging and Clinical Presentation.

Curr Probl Diagn Radiol 2020 May 17. Epub 2020 May 17.

Department of Radiology, Mayo Clinic, Rochester, MN.

Objectives: The purpose of our study is to review the imaging findings of breast metastases from nonmammary sources at our institution and to explore the mode of initial detection of these breast metastases.

Methods: In this study, we reviewed our electronic medical record and our breast imaging database for all patients who presented with nonmammary metastases to breasts between 5/1/2009 and 12/1/2019. We reviewed all available imaging data, clinical notes, and pathology reports. Read More

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http://dx.doi.org/10.1067/j.cpradiol.2020.04.010DOI Listing