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Am Fam Physician 2020 03;101(5):294-300

Medical College of Georgia at Augusta University, Augusta, GA, USA.

Upper gastrointestinal (GI) bleeding is defined as hemorrhage from the mouth to the ligament of Treitz. Common risk factors for upper GI bleeding include prior upper GI bleeding, anticoagulant use, high-dose nonsteroidal anti-inflammatory drug use, and older age. Causes of upper GI bleeding include peptic ulcer bleeding, gastritis, esophagitis, variceal bleeding, Mallory-Weiss syndrome, and cancer. Read More

Int J Clin Exp Pathol 2019 1;12(7):2758-2762. Epub 2019 Jul 1.

Lung Cancer Center, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University Chengdu, Sichuan, China.

The presence of Mallory-Weiss syndrome (MWS) in patients with small-cell lung cancer (SCLC) is uncommon. MWS is characterized by longitudinal superficial mucosal laceration at the esophagogastric junction and can be caused by a variety of causes, with upper digestive tract hemorrhage as the primary manifestation. SCLC is the most invasive histological subtype of lung cancer, and approximately a quarter of all SCLC patients undergo paraneoplastic syndrome of inappropriate antidiuretic hormone secretion, such as hyponatremia. Read More

World J Clin Cases 2019 Dec;7(24):4407-4413

Department of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular Disease, Changchun 130031, Jilin Province, China.

Background: Upper gastrointestinal bleeding (UGIB) after an acute myocardial infarction (AMI) is not an uncommon complication. Acute UGIB caused by Mallory-Weiss syndrome (MWS) is usually a dire situation with massive bleeding and hemodynamic instability. Acute UGIB caused by MWS after an AMI has not been previously reported. Read More

Middle East J Dig Dis 2019 Oct 5;11(4):225-229. Epub 2019 Nov 5.

Department of Internal Medicine, Shahid Beheshti Medical University, Tehran, Iran.

Polycythemia vera (PV) is classified as a myeloproliferative disorder (MPD). Such patients are prone to both thrombotic and hemorrhagic events. Although gastrointestinal (GI) bleeding is not a prominent manifestation of PV, it would be life threatening and necessitating hospital admission and blood transfusion if it occurs. Read More

Cureus 2019 Sep 11;11(9):e5623. Epub 2019 Sep 11.

Gastroenterology, State University of New York Upstate Medical University, Syracuse, USA.

Intramural esophageal hematoma (IEH) is a rare cause of submucosal esophageal bleeding and it is on the spectrum of esophageal wall injury along with mucosal tears (Mallory-Weiss syndrome) and full thickness perforation (Boerhaave's syndrome). Its risk factors include coagulopathy, trauma (foreign body ingestion or esophageal instrumentation) or it can happen spontaneously. It presents with a triad of chest pain, dysphagia, and hematemesis; however, the triad is only present in 35% of patients. Read More

World J Gastroenterol 2019 Sep;25(34):5174-5184

Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.

Background: Adverse events during endoscopic submucosal dissection (ESD) of superficial esophageal neoplasms, such as perforation and bleeding, have been well-documented. However, the Mallory-Weiss Tear (MWT) during esophageal ESD remains under investigation.

Aim: To investigate the incidence and risk factors of the MWT during esophageal ESD. Read More

Chirurg 2019 Aug;90(8):607-613

Universitätsklinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Deutschland.

Background: Nonvariceal upper gastrointestinal bleeding (UGIB) has a high mortality. Hematemesis sometimes with melena are the leading clinical symptoms. Peptic ulcers and (erosive) inflammation are common, whereas Mallory-Weiss syndrome, neoplasms, angiodysplasia and diffuse UGIB are less common. Read More

Dig Dis Sci 2020 01 31;65(1):225-231. Epub 2019 Jul 31.

Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, Asan Digestive Disease Research Institute, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.

Background/aims: Spontaneous retrograde migration of nasoenteral feeding tubes is common in clinical practice. The aim of the present study was to evaluate the effectiveness of nasoenteral feeding tube tip fixation with hemoclips to prevent tube dislodgement.

Methods: We retrospectively reviewed patients who underwent insertion of an endoscopic nasoenteral feeding tube with or without tube tip fixation with hemoclips at the Asan Medical Center in Korea from January 2016 to December 2017. Read More

Clin Endosc 2020 Jan 8;53(1):90-93. Epub 2019 Jul 8.

Division of Gastroenterology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.

Peptic ulcer disease is the most common cause of acute gastrointestinal bleeding, followed by variceal bleeding, Mallory-Weiss syndrome, and malignancy. On the contrary, acquired hemophilia A is a very rare hemorrhagic disease, which usually manifests with musculocutaneous bleeding, caused by autoantibodies against coagulation factor VIII. A 78-year-old man presented to the Emergency Department with melena. Read More

Frontline Gastroenterol 2019 Apr 2;10(2):112-154. Epub 2018 Nov 2.

Gastroenterology Unit, Valduce Hospital, Como, Italy.

We present an uncommon case of a patient presenting at the emergency department for severe vomiting, persisting for at least 12 hours, without nausea or abdominal pain. She initially referred vomiting food eaten several hours earlier and eventually a single episode of haematemesis with emission of a small amount of red blood and clots. She also reported the occurrence of acute dysphagia for solid food. Read More

Medicine (Baltimore) 2019 May;98(22):e15751

Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Mallory-Weiss syndrome (MWS) is a relatively less common cause of nonvariceal upper gastrointestinal bleeding. There is limited data on whether scoring systems could be used to predict the clinical outcomes in patients with bleeding due to MWS. The aim of our study is to evaluate whether the Glasgow-Blatchford score (GBS), AIMS65, and shocking index are effective in predicting the clinical outcomes of MWS. Read More

Am Surg 2019 Mar;85(3):e179-e181

BMJ Case Rep 2019 Mar 22;12(3). Epub 2019 Mar 22.

Hepatology, Bristol Royal Infirmary, Bristol, UK.

Wideochir Inne Tech Maloinwazyjne 2019 Jan 30;14(1):133-136. Epub 2018 May 30.

Department of Gastroenterology, Chinese PLA 153 Hospital, Zhengzhou, China.

There are no previous reports of Mallory-Weiss tears occurring as complications during esophageal endoscopic submucosal dissection (ESD). We present 3 cases of Mallory-Weiss tears occurring during treatment of superficial squamous cell neoplasms through ESD. Carbon dioxide was used for air insufflation, and the patient was adequately sedated without retching or struggling during the operation. Read More

Dig Dis Sci 2019 02;64(2):349-352

Division of Gastroenterology and Hepatology, Department of Medicine, University of New Mexico School of Medicine, 1 University of New Mexico, MSC10-5550, Albuquerque, NM, 87131, USA.

Medicine (Baltimore) 2018 Dec;97(49):e13191

Department of Legal and Forensic Medicine, University of Genova, Genova.

Rationale: Spontaneous esophageal rupture (Boerhaave syndrome) is a rare, though frequently fatal, event. It is generally caused by a sudden increase in pressure inside the esophagus. In some cases, full-thickness perforations of the esophagus may develop from previous lesions that initially involve only the esophageal mucosa (Mallory-Weiss syndrome) and which, following further triggering events, give rise to a transmural lesion. Read More

ACG Case Rep J 2018 26;5:e66. Epub 2018 Sep 26.

Division of Epidemiology and Biostatistics, Western Michigan University, MD Homer Stryker School of Medicine, Kalamazoo, MI.

Spontaneous intramural esophageal rupture (SIER) is a form of acute esophageal trauma defined as an injury deeper than a Mallory-Weiss tear but not extending completely through the muscular propria as in Boerhaave syndrome. SIER is a rare complication of eosinophilic esophagitis (EoE); after extensive literature review, we found 7 case reports of SIER complicating EoE. We present a case of SIER complicating EoE in a 46-year-old man with an atypical presentation requiring endoscopic clipping to achieve successful hemostasis. Read More

Dig Dis Sci 2018 12 21;63(12):3253-3261. Epub 2018 Aug 21.

Kyungpook National University Hospital, Daegu, South Korea.

Background And Aims: Compared with ulcer bleeding (UB) in non-variceal upper gastrointestinal bleeding (NVUGIB), non-ulcer bleeding (NUB) is often considered to have a low risk of poor outcomes and is treated less intensively without any risk stratification. We conducted this study to assess the predictability of scoring systems for NUB and compare the outcomes of NUB and UB.

Methods: A total of 1831 UGIB patients were registered in the database during the period from February 2011 to December 2013. Read More

Gastrointest Endosc Clin N Am 2018 Jul 17;28(3):291-306. Epub 2018 Apr 17.

Division of Gastroenterology, University of California, 9500 Gilman Drive #0956, La Jolla, CA 92093-0956, USA.

Nonvariceal, nonulcer upper gastrointestinal hemorrhage (UGIH) is a less common cause for acute upper gastrointestinal bleeding. However, nonvariceal, nonulcer UGIH is an important entity to identify and treat appropriately to prevent bleeding-related morbidity and mortality. Over the past 40 years, there has been a revolution in gastrointestinal endoscopy and a similar revolution in the management of UGIH. Read More

J Vasc Nurs 2018 06;36(2):91-93

Franciscan Health - Michigan City, Michigan City, Indiana. Electronic address:

Dis Mon 2018 Jul 7;64(7):333-343. Epub 2018 Mar 7.

Division of Gastroenterology & Hepatology, University of Texas Medical Branch, 7400 Jones Drive, Apt 724, Galveston, TX 77551.

Non-variceal upper gastrointestinal bleeding continues to be an important cause of morbidity and mortality. The most common causes include peptic ulcer disease, Mallory-Weiss syndrome, erosive gastritis, duodenitis, esophagitis, malignancy, angiodysplasias and Dieulafoy's lesion. Initial assessment and early aggressive resuscitation significantly improves outcomes. Read More

J Gastrointest Surg 2018 03 19;22(3):553-556. Epub 2018 Jan 19.

Division of Upper Gastrointestinal Surgery, Department of Surgery, National University Health System Singapore, National University of Singapore, 1E, Kent Ridge Road, NUHS Tower Block, Level 8, Singapore, Singapore.

Introduction: Endoscopic therapy remains the cornerstone of hemostasis for gastrointestinal bleeding. In situations where hemostasis cannot be achieved via endoscopic or radiological methods, surgery is necessary. Traditional open surgery for bleeding gastric ulcers can be very morbid and unsuitable especially in hemodynamically unstable patients in extremis. Read More

Am J Health Syst Pharm 2018 Feb 17;75(4):177-182. Epub 2018 Jan 17.

Memorial Regional Hospital, Hollywood, FL.

Purpose: A case report describing use of idarucizumab for dabigatran reversal without the use of hemostatic agents in a patient who developed acute upper gastrointestinal (GI) bleeding while receiving triple antithrombotic therapy is presented.

Summary: A 77-year-old man with a complex cardiac history presented to the emergency room with chief complaints of black tarry stools and low blood pressures for 4 days. His past medical history included recent percutaneous coronary intervention (PCI) and drug-eluting stent (DES) placement, atrial fibrillation, hypertension, hyperlipidemia, coronary artery disease, coronary artery bypass graft surgery, stage 3 chronic kidney disease, and cholecystectomy. Read More

J Anesth 2018 04 13;32(2):305. Epub 2018 Jan 13.

Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.

Am J Emerg Med 2018 Apr 12;36(4):665-668. Epub 2017 Dec 12.

Hacettepe University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Gastroenterology and Hepatology, Ankara, Turkey.

Introduction: Gastrointestinal bleeding is a common problem in pediatric emergency department (PED). Some of these patients can lose significant amount of blood which may lead to shock. The aim of this study is to determine the risk factors predicting clinically significant gastrointestinal (GIS) bleeding in patients presenting to PED. Read More

Dig Dis Sci 2018 05 27;63(5):1286-1293. Epub 2017 Dec 27.

Division of Gastroenterology, Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 803, MSC 623, Charleston, SC, 29425, USA.

Background: Upper gastrointestinal hemorrhage (UGIH) is common and carries substantial mortality requiring frequent hospitalizations.

Aim: To investigate trends in etiology and outcome of UGIH in hospitalized patients in the USA.

Methods: Retrospective, observational cohort study of the Nationwide Inpatient Sample from 2002 to 2012 was carried out. Read More

Tech Vasc Interv Radiol 2017 Dec 9;20(4):248-257. Epub 2017 Oct 9.

Department of Radiology, Division of Interventional Radiology and Image Guided Medicine, Emory University School of Medicine, Atlanta, GA.

Hematemesis and acute postsurgical upper gastrointestinal hemorrhage are common emergent on-call consultations for the interventional radiologist. Upper GI bleleding (UGIB) is a relatively frequent problem. The incidence and mortality vary among patient populations, but studies have shown an overall incidence ranging from 36-172 cases per 100,000 adults per year, with a mortality rate of 5%-14%. Read More

Children (Basel) 2017 Nov 3;4(11). Epub 2017 Nov 3.

Department of Paediatric Surgery, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham NG7 2UH, UK.

The aim of this study was to review the aetiology, presentation and management of these patients with upper gastrointestinal bleeding (UGIB) at a tertiary children's unit in the United Kingdom. This was a retrospective single-institution study on children (<16 years) who presented with acute UGIB over a period of 5 years using known International Classification of Diseases (ICD) codes. A total of 32 children (17 males, 15 females) were identified with a total median age at presentation of 5. Read More

Gut Liver 2017 Nov;11(6):813-820

Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.

Background/aims: Various clinical scoring systems, including the Glasgow-Blatchford score (GBS), Rockall risk score (RS), and AIMS65 score (AIMS65), have been validated to predict the clinical outcomes in patients with upper gastrointestinal bleeding (UGIB). We compared the performance of these three scoring systems in predicting clinical outcomes in patients with UGIB in Korea.

Methods: We retrospectively evaluated 286 patients with UGIB who visited emergency department. Read More

J Community Hosp Intern Med Perspect 2017 Jan 31;7(1):37-39. Epub 2017 Mar 31.

Department of Gastroenterology, Providence - Providence Park Hospital, Southfield, MI, USA.

We present an unusual case of a 44-year-old male who developed violent hiccups soon after a ureteroscopy for nephrolithiasis; later, the forceful hiccups were followed by hematemesis. Upper esophagogastroduodenoscopy revealed Mallory-Weiss tears and esophageal erosions in the lower esophagus. Esophageal biopsy was unremarkable. Read More

N Z Med J 2017 Jun 2;130(1456):80-82. Epub 2017 Jun 2.

General Surgery, Christchurch Hospital, Christchurch.

An 85-year-old female presented to hospital with haemoptysis. She underwent investigations which confirmed oesophageal submucosal haematoma. Oesophageal haematoma along with Mallory-Weiss and Boerhaave's syndromes make up acute mucosal injury of the oesophagus. Read More

Gastroenterol Res Pract 2017 27;2017:5454791. Epub 2017 Feb 27.

Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

In some cases of iatrogenic Mallory-Weiss tears (MWTs), hemostasis is needed due to severe mucosal tearing with bleeding. Therefore, we aimed to evaluate the risk factors for severe iatrogenic MWTs and the methods of endoscopic bleeding control. Between January 2008 and December 2012, 426,085 cases of screening upper endoscopy were performed at the Asan Medical Center. Read More

Insights Imaging 2017 Jun 17;8(3):365-376. Epub 2017 Mar 17.

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.

Non-malignant oesophageal diseases are critical to recognize, but can be easily overlooked or misdiagnosed radiologically. In this paper, we cover the salient clinical features and imaging findings of non-malignant pathology of the oesophagus. We organize the many non-malignant diseases of the oesophagus into two major categories: luminal disorders and wall disorders. Read More

Arab J Gastroenterol 2017 Mar 3;18(1):35-38. Epub 2017 Mar 3.

Akdeniz University School of Medicine, Department of Gastroenterology, Antalya, Turkey.

Background And Study Aims: Upper gastrointestinal (GI) bleeding is a common medical emergency. Endoscopic treatments often lead to better therapeutic outcomes than conventional conservative treatments. This study aimed to investigate and compare the use of heater probe coagulation (HPC) and argon plasma coagulation (APC) together with epinephrine injection for the treatment of Mallory-Weiss tears and high-risk ulcer bleeding. Read More

Gastroenterology 2017 05 4;152(6):1310-1318.e1. Epub 2017 Feb 4.

Department of Biomathematics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

Background & Aims: For 4 decades, stigmata of recent hemorrhage in patients with nonvariceal lesions have been used for risk stratification and endoscopic hemostasis. The arterial blood flow that underlies the stigmata rarely is monitored, but can be used to determine risk for rebleeding. We performed a randomized controlled trial to determine whether Doppler endoscopic probe monitoring of blood flow improves risk stratification and outcomes in patients with severe nonvariceal upper gastrointestinal hemorrhage. Read More

Internist (Berl) 2017 Mar;58(3):226-232

Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

Bleeding in the upper gastrointestinal (GI) tract is a frequent and complex emergency. There are guidelines for acute medical treatment, established endoscopic treatment as well as surgical and radiological rescue procedures. Nevertheless, the mortality of the upper GI tract bleeding is high, which is due to the fact that affected patients often have serious preexisting illnesses. Read More

Scand J Gastroenterol 2017 Apr 22;52(4):462-464. Epub 2016 Dec 22.

d Division of Gastroenterology, Department of Medicine , University of Miami Miller School of Medicine , Miami , FL , USA.

Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case-control studies verifying this hypothesis have been conducted.

Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS (n = 2342) in a national database and compared with age and gender-matched controls (n = 9368). Read More

N Z Med J 2016 Dec 2;129(1446):38-43. Epub 2016 Dec 2.

Gastroenterologist & Interventional Endoscopist, Department of Gastroenterology and Hepatology, Middlemore Hospital, Auckland.

Aims: A case series to review early experiences with HemosprayTM for a variety of non-variceal upper gastrointestinal bleeding (UGIB) at Middlemore Hospital.

Methods: HemosprayTM was administered therapeutically as first line or rescue at the discretion of the endoscopist. All cases of UGIB requiring HemosprayTM at Middlemore Hospital were identified to the investigator who undertook analysis of electronic and hard copy notes. Read More

J Dig Dis 2016 Oct;17(10):676-684

Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute, Seoul, Korea.

Objectives: There is limited data on whether scoring systems can be used to predict clinical outcomes in patients with upper gastrointestinal bleeding due to Mallory-Weiss syndrome (MWS). We aimed to evaluate whether the Glasgow-Blatchford score (GBS) could be effective in predicting clinical outcomes of bleeding MWS and to investigate the predictive ability of the Forrest classification for rebleeding and assess the effective endoscopic modalities for bleeding control in MWS.

Methods: From January 2004 to December 2012 168 patients were diagnosed with MWS in the Asan Medical Center Emergency Department. Read More

Surg Endosc 2017 02 28;31(2):837-842. Epub 2016 Jun 28.

Department of Gastroenterology, The First People's Hospital of Yancheng City, Yancheng, China.

Background: The key step of the endoscopic full-thickness resection (EFTR) procedure is the successful closure of any gastric wall defect which ultimately avoids surgical intervention. This report presents a new method of closing large gastric defects left after EFTR, using metallic clips and novel endoloops by means of single-channel endoscope.

Methods: We retrospectively analyzed 68 patients who were treated for gastric fundus gastrointestinal stromal tumors originating from the muscularis propria layer at four institutes between April 2014 and February 2015 and consequently underwent EFTR. Read More

Pol Przegl Chir 2016 Mar;88(2):77-86

Unlabelled: Every gastrointestinal bleeding is an immediate threat to life, requiring close supervision in a hospital setting and making it mandatory to perform verification and endoscopic intervention. In some cases of a dynamic course, in order to make up deficiencies, it is necessary to use blood and blood products. One of the causes of bleeding located proximally to the ligament of Treitz is damage to the mucous membrane and deeper layers of the gastroesophageal junction, called Mallory-Weiss syndrome. Read More

Minerva Pediatr 2016 Jun;68(3):189-95

Department of Pediatrics, St. Mary Children's Emergency Hospital, Jassy, Romania -

Background: The aim of this study was to investigate the common etiologies, clinical and biological patterns of upper gastrointestinal bleeding (UGIB) in children from a hospital center in Northeast Romania.

Methods: This seven-year retrospective study was performed from 2007 to 2013 in St. Mary Children's Emergency Hospital, Jassy, Romania and included all children who referred to our center with UGIB exteriorized by hematemesis or melena. Read More

EPMA J 2016 20;7. Epub 2016 Mar 20.

Faculty of Dentistry, The Department of Faculty Dentistry, Voronezh N.N. Burdenko State Medical University, Avenue of Revolution Str. 14, Voronezh, Russia ; Streleckaja Bol'shaja, 20 B, 69, Voronezh, 394035 Russia.

The article contains an overview of the literature on Mallory-Weiss syndrome. It analyzes numerous etiological factors, provides new insights into the pathogenesis of the disease, gives a description of a previously unknown dependence of discontinuous-hemorrhagic syndrome on the topographic and structural features of the cardioesophageal area of the digestive tract, and gives scientific credence to methods of prediction, prevention, and treatment of the syndrome with complex involvement of granular sorbents. Read More

Hepatogastroenterology 2015 Jun;62(140):907-12

Background/aims: To determine risk factors associated with mortality and increased drug costs in patients with nonvariceal upper gastrointestinal bleeding.

Methodology: We retrospectively analyzed data from patients hospitalized with nonvariceal upper gastrointestinal bleeding between January 2001-December 2011. Demographic and clinical characteristics and drug costs were documented. Read More

Case Rep Obstet Gynecol 2015 31;2015:762463. Epub 2015 Dec 31.

Division of Perinatology, Fetal Diagnosis and Therapy, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu 430-8558, Japan.

We describe a rare case of Mallory-Weiss tear with massive hematemesis at 38 weeks' gestation. A 35-year-old woman presented with epigastralgia followed by massive hematemesis. An emergency endoscopy indicated active pulsatile bleeding at the esophagocardial junction. Read More

Endoscopy 2016 1;48 Suppl 1 UCTN:E42-3. Epub 2016 Feb 1.

Department of Gastroenterology, Centro Hospitalar Vila Nova de Gaia, Espinho, Portugal.

J Surg Case Rep 2016 Jan 11;2016(1). Epub 2016 Jan 11.

Department of Surgery, Epworth Richmond Hospital, Victoria, Melbourne, Australia.

Mallory-Weiss tears (MWTs) rarely require surgical intervention. A 60-year-old female presented with massive hematemesis secondary to MWT and gastric ulceration. After failure of endoscopic management, an operative approach was embarked on, with a direct surgical hemostasis of the Mallory-Weiss tear and exclusion of the gastric ulcer. Read More

World J Gastroenterol 2016 Jan;22(1):446-66

Borko Nojkov, Mitchell S Cappell, Division of Gastroenterology and Hepatology, William Beaumont Hospital, Royal Oak, MI 48073, United States.

Aim: To systematically review the data on distinctive aspects of peptic ulcer disease (PUD), Dieulafoy's lesion (DL), and Mallory-Weiss syndrome (MWS) in patients with advanced alcoholic liver disease (aALD), including alcoholic hepatitis or alcoholic cirrhosis.

Methods: Computerized literature search performed via PubMed using the following medical subject heading terms and keywords: "alcoholic liver disease", "alcoholic hepatitis"," alcoholic cirrhosis", "cirrhosis", "liver disease", "upper gastrointestinal bleeding", "non-variceal upper gastrointestinal bleeding", "PUD", ''DL'', ''Mallory-Weiss tear", and "MWS''.

Results: While the majority of acute gastrointestinal (GI) bleeding with aALD is related to portal hypertension, about 30%-40% of acute GI bleeding in patients with aALD is unrelated to portal hypertension. Read More

Tokai J Exp Clin Med 2015 Dec 20;40(4):137-40. Epub 2015 Dec 20.

Department of Surgery, Tokai University Tokyo Hospital, 1-2-5 Yoyogi, Shibuya-ku, Tokyo 151-0053, Japan.

An 88-year-old woman, with a history of resection of stage IIA lung cancer in 1998, was referred to our hospital in August 2010 complaining of upper abdominal pain, vomiting, and dark brown stools. After endoscopic examination, she was admitted with a diagnosis of Mallory-Weiss syndrome. Vomiting occurred when food intake was resumed after fasting. Read More