5,919 results match your criteria Malignant Tumors of the Temporal Bone


Gait outcomes following proximal tibial tumor resection and endoprosthetic reconstruction.

Gait Posture 2021 May 27;88:167-173. Epub 2021 May 27.

Department of Orthopaedic Surgery/Orthopaedic Institute for Children, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Background: Despite the proximal tibia being a common site of primary malignant bone tumors, there is limited information about gait function following proximal tibial tumor resection and endoprosthetic reconstruction (PTR).

Research Question: What is the impact of PTR on gait and quality of life?

Methods: This was a cross-sectional study of patients ≥18 years old who were ≥2 years post-PTR compared to a control group of similar age and sex distribution. Eighteen participants (9 PTR, 9 Control) were recruited. Read More

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Challenges and operative strategy in an unusual case of giant mastoid osteoma.

BMJ Case Rep 2021 Jun 1;14(6). Epub 2021 Jun 1.

ENT, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

A 19-year-old female patient presented to the outpatient department of ear, nose and throat with complaints of hard swelling behind her left ear for the past 5 years. It was a large bony swelling arising from the left temporal bone causing a cosmetic deformity that was surgically excised. The patient made a good recovery post procedure. Read More

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Middle Ear and Temporal Bone Papilloma: A Clinicopathologic Study and Comprehensive Literature Review of 57 Cases.

Head Neck Pathol 2021 May 21. Epub 2021 May 21.

Department of Pathology, Southern California Permanente Medical Group, 5601 De Soto Avenue, Woodland Hills, CA, 91365, USA.

Sinonasal papilloma (SP), formerly Schneiderian papilloma, represents a rare group of benign epithelial neoplasms, most commonly identified in the sinonasal tract, while less frequently identified in the pharynx, lacrimal sac, and middle ear. Within temporal bone sinonasal-type papilloma (TBSP), there seems to be a much higher recurrence and malignant transformation risk than those identified in the sinonasal tract. Based on this clinical report and a review of the cases reported in the English literature, 49% of the 57 cases developed in the setting of concurrent or antecedent sinonasal or nasopharyngeal SP. Read More

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[Reconstruction of complex tissue defects in temporal region: report of 3 cases].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 May;56(5):487-492

Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China.

To discuss the techniques and repairing methods of various degree of compound tissue defects in the auriculotemporal region. Retrospective analysis was conducted on three cases of different repairing methods for huge compound tissue defects in different degrees in the auriculotemporal region after the resection of the malignant tumor or sinus tract due to repeated infection in our hospital. Following total removal of the tumors or sinus tract in all patients, we applied retroauricular lingual flap transfer repairing, latissimus dorsi flap free transfer repairing and vascular anastomosis, scalp tissue expansion in stage Ⅰ, then repairing the lesion with expanded scalp and filling the huge mastoid cavity with abdominal fat in stage Ⅱ, respectively, according to the characteristics of compound tissue defects in the auriculotemporal region. Read More

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[Clinical application of combined infratemporal fossa approaches for internal carotid artery in petrous bone reconstruction for large lateral skull base tumors].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 May;56(5):417-423

Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

By summarizing the technical points and therapeutic outcomes of combing infratemporal fossa approach (IFA) and internal carotid artery (ICA) reconstruction for the colossal skull base tumor invading ICA in petrous bone, the clinical application value was discussed. Five patients (2 males, 3 females,aging from 27 to 55 years old) who received surgeries between July 2015 and May 2017 for lateral skull base pathology involved petrous ICA using technique combined IFA and pre-reconstruction, were reviewed. Among the five patients, three were paraganglioma of head and neck, one was carotid aneurysms, and one was recurrent adenoid cystic carcinoma (ACC). Read More

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Malignancies requiring temporal bone resection: An Australian single-institution experience.

ANZ J Surg 2021 May 12. Epub 2021 May 12.

Queensland Skull Base Unit and Department of Otolaryngology, Head and Neck Surgery, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

Background: Malignancies in and around the temporal bone are aggressive and difficult to manage. In Queensland (Australia), where skin cancer rates are exceedingly high, tumours extending to the temporal bone from surrounding structures occur more commonly than primary cancers. Yet, a paucity of evidence exists as to their management and outcomes. Read More

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Fibrous Dysplasia Mimicking Skeletal Metastasis on 68Ga-FAPI PET Imaging.

Clin Nucl Med 2021 Apr 20. Epub 2021 Apr 20.

From the Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; and Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China.

Abstract: 68Ga-labeled fibroblast activation protein inhibitor (68Ga-FAPI) PET imaging has been introduced for detecting many primary and metastatic tumors. However, false-positive uptakes have been reported in some benign lesions. Here, we presented a 68Ga-FAPI-avid lesion in the left temporal bone in a 41-year-old man with a history of signet ring cell gastric adenocarcinoma. Read More

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Protuberant fibro-osseous lesion of the temporal bone: report of four cases and review of the literature.

Int J Oral Maxillofac Surg 2021 Apr 14. Epub 2021 Apr 14.

Service de Chirurgie Maxillo-faciale et Chirurgie Plastique, Hôpital Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris, Université de Paris, Paris, France.

'Bullough lesions', also referred to as protuberant fibro-osseous lesions (PFOL), are rare temporal bone lesions initially described in 1999. Since only 12 cases have been reported, several key issues, such as their origin and recommended management strategies, remain unresolved. This article reports the largest cohort included in the literature to date, comprising four patients with PFOL. Read More

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Aggressive progression of a facial super giant basal cell carcinoma.

BMJ Case Rep 2021 Apr 15;14(4). Epub 2021 Apr 15.

Internal Medicine, Jackson Memorial Hospital, Miami, Florida, USA

Super giant basal cell carcinoma (BCC) is a rare oncological entity. A 52-year-old man with a history of a left upper facial lesion for 11 years was transferred to our facility seeking an evaluation. He frequented multiple hospitals where he was treated with antibiotics for this condition. Read More

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The evolution of bone marrow signal changes at the skull base in nasopharyngeal carcinoma patients treated with radiation therapy.

Radiol Med 2021 Jun 31;126(6):818-826. Epub 2021 Mar 31.

Department of Radiology, University of Illinois at Chicago, Chicago, IL, USA.

Background: Clival infiltration is frequently seen in nasopharyngeal carcinoma (NPC) and the resultant bone marrow signal changes (BMSC) can persist even after complete tumor response to the radiation therapy (RT). The differentiation of those residual BMSC from recurrent/persistent disease may be challenging. We performed serial analysis of the clival BMSC after RT, to define an expected temporal evolution of those signal changes during the follow-up. Read More

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Real-Time Magnetic Resonance Guided Focused Ultrasound for Painful Bone Metastases.

J Vis Exp 2021 03 5(169). Epub 2021 Mar 5.

Department of Radiation Oncology, Taipei Medical University Hospital; Graduate Institute of Biomedical Materials & Tissue Engineering, College of Biomedical Engineering, Taipei Medical University;

Bones are one of the most common sites of cancer metastasis, which usually causes pain and impairs quality of life. Radiation therapy combined with opioids is the standard treatment for painful bone metastases. This treatment achieves effective pain control in 60-74% of patients, but limited treatment choices with limited benefits are available for recurrent or residual painful bone metastases after radiotherapy. Read More

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An Infratemporal Meningioma: A Diagnostic Dilemma.

J Radiol Case Rep 2021 Jan 31;15(1):1-10. Epub 2021 Jan 31.

Department of Radiology, Faculty of Medicine, Universiti Teknologi MARA, Malaysia.

A 46-year-old male presented with painless, recurrent bilateral ear discharge and an enlarging right temporal swelling. There were no neurological deficits. Imaging revealed an enhancing, soft tissue mass at the right infratemporal region involving the right temporalis muscle with a small, enhancing intradural component and associated hyperostosis of the greater wing of the right sphenoid bone. Read More

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January 2021

Skull base chondroblastoma presenting as a deep lobe parotid tumour.

BMJ Case Rep 2021 Feb 26;14(2). Epub 2021 Feb 26.

Otolaryngology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, Greater Manchester, UK.

Chondroblastomas are rare, benign cartilage-producing primary bone tumours that account for 1% of all primary bone tumours. They are usually seen in young adult males and affect long tubulous bones such as the femur or humerus. Occurrences in non-tubular flat bones such as the craniofacial skeleton do occur but are seen in older adults. Read More

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February 2021

Gliosarcoma in patients under 20 years of age. A clinicopathologic study of 11 cases and detailed review of the literature.

BMC Pediatr 2021 02 26;21(1):101. Epub 2021 Feb 26.

Department of Pathology and Laboratory Medicine, Section of Histopathology, Aga Khan University Hospital, Karachi, Pakistan.

Background: Gliosarcoma is a rare variant of IDH- wild type glioblastoma with both glial and mesenchymal differentiation. It accounts for approximately 2% of glioblastomas and has a poor prognosis similar to that of classic glioblastoma. It is seen mostly between 40 and 60 years of age with a mean age over 50 years. Read More

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February 2021

Intracranial Solitary Fibrous Tumor of the Skull Base: 2 Cases and Systematic Review of the Literature.

World Neurosurg 2021 May 17;149:e345-e359. Epub 2021 Feb 17.

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA; Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, Texas, USA. Electronic address:

Background: Intracranial solitary fibrous tumors (ISFTs) are rare neoplasms of mesenchymal origin that originate from the meninges. ISFTs of the skull base can be challenging to treat, as resection can be complicated by skull base anatomy. We present 2 cases of ISFT, the first manifesting with compressive cranial neuropathy from Meckel cave involvement and the second a posterior fossa lesion causing symptomatic hydrocephalus. Read More

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Neuroendocrine neoplasms of the middle ear: Unpredictable tumor behavior and tendency for recurrence.

Head Neck 2021 Jun 19;43(6):1848-1853. Epub 2021 Feb 19.

Department of Otolaryngology - Head and Neck Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Background: Middle ear adenomatous neuroendocrine tumors (MEANTs) are rare temporal bone tumors. This study evaluates its clinical behavior and therapy outcome.

Method: Retrospective case review in a tertiary referral center evaluating histopathology, immunohistochemistry, treatment, and outcome. Read More

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Malignant Transformation of Temporal Bone Schneiderian Papilloma Associated with HPV-6.

Case Rep Otolaryngol 2021 25;2021:6684254. Epub 2021 Jan 25.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty OWL, Bielefeld University, Campus Klinikum, Bielefeld, Germany.

Introduction: Temporal bone Schneiderian papillomas (TBSPs) rarely present as a primary tumors arising from the middle ear and mastoid process. The clinical findings and imaging of TBSPs are not specific. Therefore, diagnosis can only reliably be definitively established by histopathology. Read More

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January 2021

Temporal bone primary inverted papilloma - Case Report and review of the literature.

Laryngorhinootologie 2021 02 1;100(2):99-103. Epub 2021 Feb 1.

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Medizinische Hochschule Hannover, Germany.

Inverted papilloma of middle ear is an extremely rare lesion of the respiratory epithelium that normally occurs in the nasal cavity and paranasal sinuses. So far less than 17 cases were described in literature. A 45-year-old patient was admitted in our Department with hearing loss, otorrhea and pulsing tinnitus on the right ear. Read More

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February 2021

Navigated, endoscopically controlled, transtympanic resection of an infracochlear cholesteastoma recurrence.

HNO 2021 Jan 26;69(Suppl 1):31-33. Epub 2021 Jan 26.

Department of Otorhinolaryngology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Killianstraße 5, 79106, Freiburg, Germany.

An infracochlear cholesteatoma of the petrous apex with direct contact to the internal carotid artery (ICA) is rare. Due to the risk of cochlear injury with consecutive deafness or injury of the ICA, precise preoperative planning of the approach and strategy is recommended, as well as thorough preoperative counseling of the patient for their informed consent. This case report presents navigated endoscopically controlled transtympanic resection of such a cholesteatoma recurrence. Read More

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January 2021

The Experience of a Facial Nerve Unit in the Treatment of Patients With Facial Paralysis Following Skull Base Surgery.

Otol Neurotol 2020 Dec;41(10):e1340-e1349

Department of Otorhinolaryngology.

: The management of facial paralysis following skull base surgery is complex and requires multidisciplinary intervention. This review shows the experience of a facial nerve (FN) unit in a tertiary university referral center. A multidisciplinary approach has led to the breaking of some old treatment paradigms. Read More

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December 2020

Not So Benign Bell's Palsy: Malignant Peripheral Nerve Sheath Tumor of the Facial Nerve Involving the Temporal Bone.

J Gen Intern Med 2021 04 19;36(4):1102-1105. Epub 2021 Jan 19.

Department of Medicine, Baylor College of Medicine and Smith Clinic, Houston, TX, USA.

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Unforeseen progressive outer retinal necrosis in a child following bone marrow transplant.

BMJ Case Rep 2021 Jan 6;14(1). Epub 2021 Jan 6.

Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, Delhi, India

A 10-year-old boy underwent stem cell transplant for Hodgkin's lymphoma and developed vomiting and seizure in the postoperative period. An ophthalmic referral was made from intensive care unit, to rule out papilledema. On examination, there was no papilledema in both eyes, instead there were areas of retinal necrosis with no haemorrhages or vitritis in right eye. Read More

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January 2021

Management of Temporal Bone Malignancy in Ireland.

J Neurol Surg B Skull Base 2020 Dec 29;81(6):680-685. Epub 2019 Aug 29.

Department of Otolaryngology/Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland.

 Lateral temporal bone malignancy remains a challenging rare disease. We report 17 years of multidisciplinary care of these tumors with univariate and multivariate analyses of key prognostic indicators for consideration in contemporary oncological management.  This is a retrospective cohort study. Read More

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December 2020

Management of esotropia: hypotropia in neurofibromatosis type 1 - simulating myopic strabismus fixus.

BMJ Case Rep 2020 Dec 17;13(12). Epub 2020 Dec 17.

Jasti V Ramanamma Children's Eye Care Center, Child Sight Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India

A 28-year-old man presented with a progressive inward deviation of the left eye in the last 4 years. Examination revealed -3 abduction and elevation deficit in the left eye with 50 prism diopters (PD) esotropia and 12 PD of hypotropia. The patient had multiple fibromas on the forearms with pulsatile globe and was diagnosed as neurofibromatosis type 1. Read More

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December 2020

The Risk of Spread of Infection During Craniotomy/Craniostomy on Patients with Active Coronavirus Disease 2019 (COVID-19) Infection: Myth or Fact?

World Neurosurg 2021 03 14;147:e272-e274. Epub 2020 Dec 14.

Department of Neurosurgery, PGIMER, Chandigarh, India.

Objectives: Craniotomies/craniostomies have been categorized as aerosol-generating procedures and are presumed to spread coronavirus disease 2019 (COVID-19). However, the presence of severe acute respiratory distress syndrome coronavirus 2 virus in the generated bone dust has never been proved. Our objective is to evaluate the presence of virus in the bone dust (aerosol) generated during emergency neurosurgical procedures performed on patients with active COVID-19. Read More

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-rearranged diffuse large B-cell lymphoma in a child: a case report and molecular characterization.

Pediatr Hematol Oncol 2021 Apr 5;38(3):281-289. Epub 2020 Nov 5.

Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

-rearranged diffuse large B-cell lymphoma (DLBCL) is rare in both the adult and pediatric populations, and its biological features are unclear. We here report the case of a 19-month-old female with a right temporal bone tumor that was ultimately diagnosed as DLBCL by tumor biopsy. There was no morphological evidence of bone marrow infiltration at diagnosis. Read More

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[A case of diagnostics and surgical treatment of a patient with a neuroma of the facial nerve].

Vestn Otorinolaringol 2020 ;85(5):24-28

Research Clinical Institute of Otorinolaryngology named after. L.I. Sverzhevsky, Moscow, Russia.

The article provides a brief overview of the epidemiology of facial nerve neuromas (FNN, schwannomas), its clinical signs, methods of diagnostic and treatment and indications for their use. A rare clinical case of diagnostics, surgical treatment of FNN with intracranial spread and its results are described in detail. The presented case demonstrates a possible low-symptom course of FNN with intracranial spread. Read More

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November 2020

Vascularized Composite Parietal Bone Flap for Immediate Reconstruction of a Hemi-Maxillectomy Defect in an Infant.

J Craniofac Surg 2020 Nov/Dec;31(8):2334-2338

Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT.

Background: Surgical resection of maxillary tumors can result in defects that can be difficult to reconstruct by conventional means due to the complex functional and anatomic nature of the midface and lack of regional bone flap options in the head and neck. Many reconstructive methods have been used to repair maxillary defects, but the ideal technique for the reconstruction of hemi-maxillectomy defects in growing pediatric patients has yet to be determined.

Methods: The authors present a rare pediatric patient with melanotic neuroectodermal tumor of infancy resulting in a hemi-maxillectomy defect after resection that was reconstructed using a pedicled vascularized composite flap consisting of temporalis muscle, pericranium, and parietal bone. Read More

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Sinonasal Chondrosarcoma Presenting With Isolated Severe Vision Loss.

J Neuroophthalmol 2020 Oct 27. Epub 2020 Oct 27.

Department of Ophthalmology and Vision Sciences (MTBN, JAM), University of Toronto, Toronto, Ontario, Canada; Faculty of Medicine (AF), University of Toronto, Toronto, Ontario, Canada; Department of Pathology and Laboratory Medicine (BCD), Mount Sinai Hospital; Department of Laboratory Medicine and Pathobiology (BCD), University of Toronto, Toronto, Ontario, Canada; Department of Otolaryngology-Head and Neck Surgery (JML), St. Michael's Hospital, Toronto, Ontario, Canada; Department of Otolaryngology-Head and Neck Surgery (JML), University of Toronto, Toronto, Ontario, Canada; Division of Neurosurgery (MDC), Department of Surgery, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Surgery (MDC), University of Toronto, Toronto, Ontario, Canada; Radiation Medicine Program (DST), Princess Margaret Cancer Centre, University Health Network; Department of Radiation Oncology (DST), University of Toronto, Toronto, Ontario, Canada; Division of Neurology (JAM), Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and Department of Ophthalmology (JAM), St. Michael's Hospital, Toronto, Ontario, Canada.

A 24-year-old man presented with a 2-month history of progressive, painless vision loss in the right eye, with no history of headache, nasal congestion, rhinorrhea, or epistaxis. His visual acuity was counting fingers at 1 ft in the right eye and 20 of 20 in the left eye with a right relative afferent pupillary defect and mild temporal optic disc pallor. MRI of the brain and orbits showed a mass involving bilateral ethmoid and sphenoid sinuses and right nasal cavity. Read More

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October 2020

Temporal hemiarthroplasty for distal femoral osteosarcoma in early childhood: a case report.

World J Surg Oncol 2020 Oct 28;18(1):280. Epub 2020 Oct 28.

Department of Orthopaedic Oncology and Surgery, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 3501298, Japan.

Background: Prosthetic reconstruction for distal femoral osteosarcoma is challenging for younger children. We herein report a successful case of limb-sparing surgery for a younger patient with distal femoral osteosarcoma requiring osteo-articular resection.

Case Presentation: A 5-year-old girl with high-grade conventional osteosarcoma in the left distal femur underwent a series of surgeries. Read More

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October 2020