13,478 results match your criteria Malignant Tumors of the Sinuses


Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis.

Biomed Res Int 2022 14;2022:4931210. Epub 2022 Jun 14.

Department of Neurosurgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu, China.

The main aim of this study was to investigate the therapeutic effect of endovascular interventional therapy on cerebral venous sinus thrombosis (CVST). 137 patients with CVST were included, 92 patients were treated with interventional therapy, and 45 patients were treated with conventional anticoagulant therapy. Through endovascular therapy (EVT) combined with therapy, the patients were treated with EVT in combination with conventional anticoagulant therapy, and the prognosis of the two groups of patients was evaluated. Read More

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[Metachronous multiple carcinoma of bilateral maxillary sinus and lung: a case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 Jun;57(6):746-748

Department of Otorhinolaryngology Head and Neck Surgery, the Second Hospital of Jilin University, Changchun 130041, China.

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Direct intracranial invasion of eccrine spiradenocarcinoma of the scalp: a case report and literature review.

BMC Neurol 2022 Jun 18;22(1):223. Epub 2022 Jun 18.

Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.

Background: Eccrine spiradenocarcinoma (SC), also known as malignant eccrine spiradenoma, is a rare malignant cutaneous adnexal neoplasm arising from long-standing benign eccrine spiradenoma. Malignant skin tumors rarely show direct intracranial invasion. However, once the intracranial structure is infiltrated, curative excision with sufficient margins can become extremely difficult, particularly when the venous sinuses are involved. Read More

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Osteosarcoma of the distal fibula and reconstruction of the ankle using inverted fibula, a case report.

Int J Surg Case Rep 2022 Jun 14;96:107310. Epub 2022 Jun 14.

Alzaiem Alazhari University, Department of Surgery, Sudan. Electronic address:

Introduction And Importance: Osteosarcomas are malignant primary bone tumors of mesenchymal origin producing osteoid material and has peak incidence in adolescents. Distal lower limb tumors are rare and can negatively affect ankle joint stability.

Case Presentation: A 24-year-old female who has newly graduated from college presented with distal fibular mass measuring around 5 × 15 cm located on the lateral aspect of the right ankle over a period of 2 months. Read More

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NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study.

Leuk Lymphoma 2022 Jun 14:1-10. Epub 2022 Jun 14.

Eye Pathology Section, Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Compared to Asian and Latin American populations, sinonasal NK- or T-cell lymphoma is rare in Europe. All patients with sinonasal NK- or T-cell lymphoma in Denmark from 1980 to 2017 were validated histologically, and the disease behavior and demographics were extracted from medical records and national registries. Prognostic factors associated with mortality were determined using survival statistics. Read More

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Infra-Temporal and Pterygo-Palatine Fossae Tumors: A Frontier in Endoscopic Endonasal Surgery-Description of the Surgical Anatomy of the Approach and Report of Illustrative Cases.

Int J Environ Res Public Health 2022 May 25;19(11). Epub 2022 May 25.

Programma Neurochirurgia Ipofisi-Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.

Infratemporal and pterygopalatine fossae (ITF and PPF) represent two complex paramedian skull base areas, which can be defined as jewelry boxes, containing a large number of neurovascular and osteomuscular structures of primary importance. They are in close communication with many craniofacial areas, such as nasal/paranasal sinuses, orbit, middle cranial fossa, and oral cavities. Therefore, they can be involved by tumoral, infective or inflammatory lesions spreading from these spaces. Read More

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Fenestration is a logical and effective treatment for a large primordial cyst with cholesterol granuloma: a case report.

J Int Med Res 2022 Jun;50(6):3000605221104185

Department of Oral and Maxillofacial Surgery, Matsue City Hospital, Shimane 690-8509, Japan.

A cholesterol granuloma (CG) is characterized by the presence of cholesterol crystals that cause a chronic granulomatous reaction in an enclosed space. It occurs most commonly in the head and neck region, particularly in the middle ear. Although CGs in the maxilla have also been reported, odontogenic cysts in conjunction with CGs in the maxilla are very rare. Read More

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Advanced squamous cell carcinoma with massive cranial invasion: walking around without a forehead.

Dermatol Online J 2022 Mar 15;28(2). Epub 2022 Mar 15.

Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.

Squamous cell carcinomas with widespread invasion of the skull, meninges and brain parenchyma are extremely rare. Herein, we present an 86-year-old man with an 18-year history of sunburn who developed a large osteodestructive SCC that invaded through the frontal bone, frontal sinuses, and the dura mater. No neurological signs or symptoms or distant metastasis were noted. Read More

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[Anatomy for Endoscopic Endonasal Skull Base Surgery].

No Shinkei Geka 2022 May;50(3):535-543

Department of Otolaryngology-Head and Neck Surgery, Nagoya City University, Graduate School of Medical Sciences.

Endoscopic endonasal skull base surgery has become popular due to its minimally invasive nature to the patient and the development of various medical devices. The reason why it is considered less invasive is that it is possible to reach the anterior skull base lesion using the corridor of the nasal cavity and paranasal sinuses. The roles of the nasal sinuses include acting as breathing pathways, warming, humidifying, and filtering of inhaled air, olfaction, and being a resonant cavity, all of which are important for a comfortable life, and the loss of these functions reduces the quality of life. Read More

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Current opinions on diagnosis and treatment of adenoid cystic carcinoma.

Oral Oncol 2022 Jul 2;130:105945. Epub 2022 Jun 2.

Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Otolaryngology Major Disease Research Key Laboratory of Hunan Province, Changsha, Hunan 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Anatomy Laboratory of Division of Nose and Cranial Base, Clinical Anatomy Center of Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. Electronic address:

Adenoid cystic carcinoma (ACC) is a rare malignant tumor derived mainly from the salivary glands, representing approximately 1% of all headandneck carcinomasand 10% of all salivary gland neoplasms. ACC displays a paradoxical behavioral combination of an indolent growth pattern but an aggressive progression, with local recurrence and distant metastasis. The propensity of ACC of the head and neck (ACCHN) for perineural invasion and its anatomical location, especially if it extends to the nasal cavity and paranasal sinuses, facilitates tumor involvement in the surrounding structures, such as the orbit, pterygopalatine fossa, Meckel'scave, and cavernous sinus, which can lead to skull base involvement and intracranial extension. Read More

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Limberg Flap Technique For Pilonidal Sinus Disease Treatment: An Experience Of Hamdard University Hospital.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):230-234

Department of Surgery, Hamdard University Hospital, Karachi, Pakistan.

Background: Pilonidal sinus disease (PNSD) is considered as the challenging disease for surgeons since decades. The term pilo-nidal is derived from Latin meaning "nest of hair". It is a commonly occurring disease usually involved young male adults. Read More

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Adenoid cystic carcinoma of sinonasal origin masquerading as an intraconal lesion.

BMJ Case Rep 2022 May 13;15(5). Epub 2022 May 13.

Radiodiagnosis, Datta Meghe Institute of Medical Sciences - Wardha Campus, Wardha, Maharashtra, India.

Adenoid cystic carcinoma is an uncommon tumour of the salivary glands, although affliction of mucin-producing glands present in the oral cavity, oropharynx and paranasal sinuses is not uncommon. Other possible sites are lacrimal, oesophagus, trachea-bronchial tree, lungs, uterus, cervix, prostate. These tumours have a tendency to be aggressive and most show invasion into the adjacent region. Read More

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Biological roles and clinical significance of estrogen and androgen receptors in head and neck cancers.

J Cancer 2022 4;13(7):2189-2199. Epub 2022 Apr 4.

General Hospital, Clinical Medical Academy, Shenzhen University, Shenzhen 518055, Guangdong, China.

Head and neck cancers (HNC) include malignant tumors that grow in and around the mouth, larynx, throat, sinuses, nose, and salivary glands. Accumulating evidence in malignancies suggests the aberrant expressions of the estrogen receptor (ER) and the androgen receptor (AR) in HNC, such as in laryngeal cancer and cancer of the salivary gland. Moreover, the signaling pathways involving these receptors that mediate tumorigenesis, proliferation, apoptosis, migration, and invasion have been elucidated. Read More

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[Low-grade non-intestinal adenocarcinoma of the nasal cavity and paranasal sinuses with ETV6 gene rearrangement:report of a case].

Zhonghua Bing Li Xue Za Zhi 2022 May;51(5):461-463

Department of Pathology, the People's Hospital of Jiangsu Province (the First Affiliated Hospital of Nanjing Medical University), Nanjing 210029, China.

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A Systematic Review of Nasal Chondromesenchymal Hamartoma (NCMH) with a New Case Report.

Head Neck Pathol 2022 May 4. Epub 2022 May 4.

Clinical Dermatology, Leatherhead Hospital, Leatherhead, UK.

Nasal chondromesenchymal hamartoma (NCMH) is a very rare, benign sinonasal tract tumor commonly affecting infants. In this paper, in addition to presenting a systematic review of the literature on NCMH, we also report an unusual case of NCMH in an adolescent patient. A systematic review conducted following the PRISMA guidelines. Read More

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Two cases of neurilemmoma in the nasal vestibule: A case report and literature review.

Medicine (Baltimore) 2022 Mar 11;101(10):e29006. Epub 2022 Mar 11.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea.

Rationale: Neurilemmoma is a benign tumor derived from the Schwann cells of the nerve sheath. The highest incidence of neurilemmoma occurs in the head and neck region; however, the nose and paranasal sinuses are rarely involved. Less than 4% of these tumors involve the nasal cavity and paranasal sinuses. Read More

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Adenoid Cystic Carcinoma with Intracranial Extension.

Arch Iran Med 2022 03 1;25(3):191-193. Epub 2022 Mar 1.

Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.

Adenoid cystic carcinoma (ADCC) is a malignant tumor of salivary gland origin. ADCC of sinonasal tract is rare. We present a rare and unresectable case of sinonasal ADCC with intracranial extension in an 83-year-old man with the chief complaint of nasal congestion. Read More

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Teratocarcinosarcoma of the cheek: a case report.

J Surg Case Rep 2022 Apr 12;2022(4):rjac169. Epub 2022 Apr 12.

Department of Pathology, Mohammed V Military Hospital, Rabat, Morocco.

Teratocarcinosarcoma is a rare and aggressive malignant tumor of uncertain histogenesis. It presents <1% of all cancers and ~3% of malignant tumors of the head and neck. It arises commonly from the nasal cavity and paranasal sinuses. Read More

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Optic Perineuritis Associated With Cryptococcal Meningitis Presenting With a "Hot Orbit" in a Patient With Chronic Lymphocytic Leukemia.

J Neuroophthalmol 2022 06 23;42(2):272-277. Epub 2022 Mar 23.

Department of Ophthalmology (DLL, BKC, EDG), Mass Eye and Ear, Boston, Massachusetts; Department of Ophthalmology (EKT), Boston Medical Center, Boston, Massachusetts; Department of Pathology (MYL), Boston VA Medical Center, Boston, Massachusetts; Department of Optometry (JEK), Boston VA Medical Center, Boston, Massachusetts; Department of Radiology (NJF), Stanford University Medical Center, Stanford, California; Department of Ophthalmology (DRL), Boston VA Medical Center, Boston, Massachusetts; Division of Ophthalmic Plastic and Reconstructive Surgery (DRL), Massachusetts Eye and Ear, Boston, Massachusetts; Division of Neuro-Immunology (BKC), Massachusetts General Hospital, Boston, Massachusetts; Department of Ophthalmology (EDG), Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; and Picower Institute for Learning and Memory (EDG), Massachusetts Institute of Technology, Cambridge, Massachusetts.

Abstract: A 75-year-old man presented with 3 days of progressive left retro-orbital pain, eyelid swelling, tearing, and pain with extraocular movement. His medical history was significant for type II diabetes mellitus and chronic lymphocytic leukemia, stable on no therapy since diagnosis 8 years prior. The initial examination was significant for diffuse restriction of left ocular motility, marked lid edema, and mild dyschromatopsia. Read More

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Management of Head and Neck Mucosal Melanoma.

Oral Maxillofac Surg Clin North Am 2022 May 8;34(2):299-314. Epub 2022 Apr 8.

Head and Neck Unit, The Royal Marsden Hospital, London, UK; Division of Radiotherapy and Imaging, Targeted Therapy Team, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, United Kingdom.

Head and neck mucosal melanomas are uncommon and aggressive malignancies that arise mainly in the nasal cavity and paranasal sinuses, with the next commonest site being the oral cavity. The mainstay of treatment is radical surgical resection. Adjuvant radiotherapy improves locoregional control but does not improve overall survival. Read More

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Cancer Occurrence After a Cerebral Venous Thrombosis: A Nationwide Registry Study.

Stroke 2022 05 5;53(5):e189-e191. Epub 2022 Apr 5.

Heart Center and Center for Population Health Research (V.K.), Turku University Hospital and University of Turku, Finland.

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Growth hormone secreting pituitary adenomas show distinct extrasellar extension patterns compared to nonfunctional pituitary adenomas.

Pituitary 2022 Jun 25;25(3):480-485. Epub 2022 Mar 25.

USC Brain Tumor Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Purpose: Patterns of extension of pituitary adenomas (PA) may vary according to PA subtype. Understanding extrasellar extension patterns in growth hormone PAs (GHPA) vis-a-vis nonfunctional PAs (NFPAs) may provide insights into the biology of GHPA and future treatment avenues.

Methods: Preoperative MR imaging (MRI) in 179 consecutive patients treated surgically for NFPA (n = 139) and GHPA (n = 40) were analyzed to determine patterns of extrasellar growth. Read More

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Endoscopic Far-Lateral Supracerebellar Infratentorial Approach for Petroclival Region Meningioma: Surgical Technique and Clinical Experience.

Oper Neurosurg (Hagerstown) 2022 05;22(5):290-297

Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai, China.

Background: The management of petroclival region meningioma remains the ultimate achievement in neurosurgery, because of the formidable technical challenges involved.

Objective: To describe the technique and feasibility of the purely endoscopic far-lateral supracerebellar infratentorial approach (EF-SCITA) for the treatment of petroclival region meningiomas.

Methods: We reviewed the clinical data of 10 consecutive cases of petroclival region meningiomas treated with the EF-SCITA from August 2018 to August 2020. Read More

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Sinonasal Mucosal Melanoma: An Update and Review of the Literature.

Am J Dermatopathol 2022 Jun 22;44(6):424-432. Epub 2022 Mar 22.

Pathology Service, Dermatopathology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Abstract: Primary sinonasal mucosal melanoma (SNMM) is an aggressive tumor with high metastatic potential and poor outcomes. Presenting symptoms are nonspecific, and the nasal cavity is the most common site of origin followed by the maxillary and ethmoid sinuses. Histopathologically, SNMMs are pleomorphic and predominantly composed of epithelioid cell type. Read More

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Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Nasal Cavity, Paranasal Sinuses and Skull Base.

Head Neck Pathol 2022 Mar 21;16(1):1-18. Epub 2022 Mar 21.

University of Texas Southwestern Medical Center, Clements University Hospital, UH04.250, 6201 Harry Hines Blvd., Dallas, TX, 75390, USA.

The World Health Organization Classification of Head and Neck Tumours recently published the 5th edition. There are new entities, emerging entities, and significant updates to the taxonomy and characterization of tumor and tumor-like lesions, specifically in this article as it relates to nasal cavity, paranasal sinuses and skull base. Importantly, the number of diagnostic entries has been reduced by creating category-specific chapters for soft tissue, hematolymphoid, melanocytic, neuroectodermal, and metastatic tumors. Read More

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Hypopituitarism and cranial nerve involvement mimicking Tolosa-Hunt syndrome as the initially presenting feature of diffuse large B-cell lymphoma: a case report.

BMC Endocr Disord 2022 Mar 14;22(1):65. Epub 2022 Mar 14.

The First Department of Medicine, Wakayama Medical University, Wakayama, Japan.

Background: Early diagnosis of lymphoma involving the central nervous system is sometimes difficult but emergent to avoid the delay of therapeutic initiation. Pituitary insufficiencies are usually associated with lymphoma in the pituitary gland. There have been no cases of lymphoma originating from extra pituitary gland with hypopituitarism that simultaneously presenting unilateral upper cranial nerve palsies and ophthalmalgia. Read More

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NCCN Guidelines® Insights: Head and Neck Cancers, Version 1.2022.

J Natl Compr Canc Netw 2022 03;20(3):224-234

The University of Texas MD Anderson Cancer Center.

The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity (including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer, salivary gland cancer, and mucosal melanoma (MM) are also addressed. The specific site of disease, stage, and pathologic findings guide treatment (eg, the appropriate surgical procedure, radiation targets, dose and fractionation of radiation, indications for systemic therapy). Read More

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Surgical Considerations in Endoscopic Pituitary Dissection for the Neurosurgeon.

Otolaryngol Clin North Am 2022 Apr 4;55(2):389-395. Epub 2022 Mar 4.

Neurosurgery & Neuroscience Institute, University of Pittsburgh Medical Center Central Pennsylvania, 205 South Front Street, 6th Floor, Suite 6A, Harrisburg, PA 17104, USA. Electronic address:

Many surgical considerations exist for an endoscopic approach for pituitary surgery for a neurosurgeon. The neurosurgical approach to endoscopic pituitary dissection requires proper surgical planning and identification of relevant anatomic structures. With the introduction of endoscopic transsphenoidal pituitary surgery, better visualization and more intricate surgical resections are achieved. Read More

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