13,131 results match your criteria Malignant Tumors of the Sinuses

Sinonasal Renal Cell-Like Adenocarcinoma.

Cureus 2021 Apr 4;13(4):e14285. Epub 2021 Apr 4.

Otolaryngology - Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA.

Sinonasal renal cell-like adenocarcinoma (SNRCLA) is a newly defined, rare malignant tumor of the nasal cavity. The clinical course and response to treatment remain uncertain. The purpose of this study is to report a new case of SNRCLA and review the literature to determine clinical characteristics, treatment options, and outcomes. Read More

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Sinonasal Extramedullary Plasmacytoma With Rare Osteolytic Lesions.

Cureus 2021 Mar 31;13(3):e14220. Epub 2021 Mar 31.

Orthopedics, General Hospital of Patras, Patras, GRC.

Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate either from bone or soft tissue and could be primary or a part of a systemic process during the course of multiple myeloma. Extramedullary plasmacytomas (EPs) in the sinonasal tract or nasopharynx are rare and mostly presented as case reports. Read More

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[Reconstruction of oncological defects of the perianal region].

Chirurg 2021 Apr 27. Epub 2021 Apr 27.

Plastisch- und Handchirurgische Klinik und Labor für Tissue Engineering und Regenerative Medizin, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg FAU, Krankenhausstraße 12, 91054, Erlangen, Deutschland.

In addition to the progressive development of surgical oncological techniques for malignant tumors of the rectum, anal canal and vulva, reconstructive procedures after oncological interventions in the perianal region represent a cornerstone in the postoperative quality of life of patients. Modern treatment modalities for rectal cancer with neoadjuvant chemoradiotherapy increase the survival rate and simultaneously reduce the risk of local recurrence to 5-10%, especially by cylindrical extralevatory extirpation of the rectum. The price for increased surgical radicality and improved oncological safety is the acceptance of larger tissue defects. Read More

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Clinical, anatomopathological, and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog.

Open Vet J 2021 Jan-Mar;11(1):1-5. Epub 2021 Jan 3.

Department of Veterinary Medicine, University of Vila Velha, Vila Velha, Brazil.

Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region. Some malignant nasal cavity neoplasms may invade the brain causing clinical neurological signs, as well as purulent nasal secretion and epistaxis.

Case Description: A case of neoplasm is reported in a 14-year-old pincher presenting dyspnea, epistaxis, and neurological alterations. Read More

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January 2021

Solitary extramedullary plasmacytoma presenting as an adrenal tumor: case report and literature review.

Gland Surg 2021 Mar;10(3):1158-1164

Department of General Surgery, The Third Xiangya Hospital of Central South University, Changsha, China.

Solitary extramedullary plasmacytoma, an extremely rare case which accounts for about 3% of all plasma cell neoplasms, often occurs in the head and neck region such as para nasal sinuses, nasal cavity and oral cavity, it also occurs in the lymph nodes, lungs, thyroid, intestine, liver, pancreas, testis, breast, or skin. Isolated primary plasmacytoma of adrenal is extremely rare and only nine documented cases have been reported in the literature. We are presenting the 10 case which is the youngest patient until now with symptoms of fever and hepatosplenomegaly. Read More

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Case Report: SMARCB1 (INI-1)-Deficient Carcinoma of the Nasal Cavity with Pure Yolk Sac Tumor Differentiation and Elevated Serum AFP Levels.

Onco Targets Ther 2021 29;14:2227-2233. Epub 2021 Mar 29.

Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, 110001, People's Republic of China.

In adults, yolk sac tumors (YSTs) in the nasal cavity and paranasal sinuses are very rare. To date, only six cases have been reported in the English literature. YSTs in adults are often accompanied by cancer, teratocarcinosarcoma, and other malignant components. Read More

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Aggressive squamous cell carcinoma of the cranium of a dog.

BMC Vet Res 2021 Apr 6;17(1):144. Epub 2021 Apr 6.

Department and Clinic of Animal Surgery, Laboratory of Radiology and Ultrasonography, University of Life Sciences, Głęboka 30, 20-612, Lublin, Poland.

Background: The authors report a case of keratinized squamous cell carcinoma (SCC) in a 14-year-old dog with extensive cranial bone invasion. To our knowledge, this is the first description of such a case of cranial keratinized SCC with aggressive generalized osteolysis described in a dog.

Case Presentation: The 14-year-old dog was referred for radiological examination with suspicion of head trauma with clinical signs of head deformation, exophthalmos and nasal discharge. Read More

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[Diagonistic and prognostic analysis of olfactory neuroblastoma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;35(3):224-228

Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of Qingdao University,Qingdao,266003,China.

To explore the therapeutic effect and prognostic risk factors of olfactory neuroblastoma. Retrospective analysis of clinical data of 31 patients with olfactory neuroblastoma. The Kaplan-Meier method was used for survival analysis to calculate the overall survival rate and progress-free survival rate. Read More

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[Follow-up care of sinonasal papillomas - risk factors for recurrence and malignant progression].

Laryngorhinootologie 2021 04 30;100(4):261-269. Epub 2021 Mar 30.

Klinik für Hals-Nasen-Ohrenheilkunde, KRH-Klinikum Nordstadt, Hannover, Germany.

Objective: Sinonasal papillomas are tumors of the nasal cavity and paranasal sinuses. They are treated through complete resection under oncologic conditions. Two characteristics complicate follow-up: 1) frequent tumor recurrences (even many years after initial diagnosis), 2) possibility for malignant progression. Read More

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Ophthalmic Presentation and Outcomes for Malignant Sinonasal Tumors.

Ophthalmic Plast Reconstr Surg 2021 Mar 24. Epub 2021 Mar 24.

Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.

Purpose: To evaluate the ophthalmic clinical features and functional outcomes for patients with malignant sinonasal tumors who initially presented with orbital symptoms.

Patients And Methods: Retrospective chart review for patients seen at Moorfields Eye Hospital between 1997 and 2020. Patient demographics and clinical features, radiology, histology, and treatment outcomes were reviewed. Read More

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Endoscopic assisted removal - An aesthetic approach to impacted third molar tooth in the orbital floor.

Indian J Dent Res 2020 Nov-Dec;31(6):983-986

Department of ENT, Grant Government Medical College, Mumbai, Maharashtra, India.

A third molar displaced in the orbital floor is a very rare sighting. The usual surgical approach to such a case is the Caldwell Luc procedure that has its own complications. Here in this article, we present a 17-year-old male patient with third molar displaced in the orbital floor with egg shell thin anterior wall. Read More

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Sustained remission of multi-line relapsed extranodal NK/T-cell lymphoma, nasal type, following sintilimab and chidamide: A case report.

Medicine (Baltimore) 2021 Mar;100(10):e24824

Department of Hematology.

Introduction: There is currently no optimal treatment modality for refractory or relapsed Extranodal NK/T-cell lymphoma, nasal type (ENKTL). In recent years, programmed cell death protein 1 (PD-1)/programmed cell - ligand 1 pathway blockade and histone deacetylase inhibitors have emerged as promising strategies for refractory or relapsed ENKTL. Accumulating evidence has shown that therapeutic effects of anti-PD-1 antibody could be enhanced by histone deacetylase inhibitors. Read More

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Primary yolk sac tumor of pterygopalatine fossa with loss of vision: A case report.

Medicine (Baltimore) 2021 Feb;100(8):e24916

Department of Emergency Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine; Research Institute of Emergency Medicine, Zhejiang University, Hangzhou, China.

Introduction: Primary yolk sac tumor (YST) is an infrequently-diagnosed malignant extragonadal germ cell tumors. It is likely to recur locally and may present with widespread metastases once diagnosed. Primary YST of the head is uncommon but can cause severe complications, such as loss of vision once the tumor mass invades the optic nerve. Read More

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February 2021

Clinico-pathological Profile of Head and Neck Tumours with Intracranial Extension.

M O Udoh D O Udoh

West Afr J Med 2021 Feb;38(2):131-136

Department of Surgery,University of Benin/University of Benin Teaching Hospital,Benin City. Edo State, Nigeria.

Background: Intracranial extensions of Head and Neck region tumours are a result of direct spread, into the brain and meninges, of tumours arising in the pharynx, paranasal sinuses, orbit, middle ear, scalp, skull and neck tissues. Presenting features may resemble those of an intracranial mass, or the contiguous structure of origin, or both. Delayed diagnosis is not uncommon when patients are not able to afford diagnostic imaging or when the possibility of an intracranial extension is not readily considered in the evaluation of patients with head and neck lesions. Read More

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February 2021

Study of the physicochemical properties of drugs suitable for administration using a lymphatic drug delivery system.

Cancer Sci 2021 May 16;112(5):1735-1745. Epub 2021 Mar 16.

Laboratory of Biomedical Engineering for Cancer, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan.

Lymph node (LN) metastasis is thought to account for 20-30% of deaths from head and neck cancer. The lymphatic drug delivery system (LDDS) is a new technology that enables the injection of drugs into a sentinel LN (SLN) during the early stage of tumor metastasis to treat the SLN and secondary metastatic LNs. However, the optimal physicochemical properties of the solvent used to carry the drug have not been determined. Read More

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Temporal bone primary inverted papilloma - Case Report and review of the literature.

Laryngorhinootologie 2021 02 1;100(2):99-103. Epub 2021 Feb 1.

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Medizinische Hochschule Hannover, Germany.

Inverted papilloma of middle ear is an extremely rare lesion of the respiratory epithelium that normally occurs in the nasal cavity and paranasal sinuses. So far less than 17 cases were described in literature. A 45-year-old patient was admitted in our Department with hearing loss, otorrhea and pulsing tinnitus on the right ear. Read More

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February 2021

Glomangiopericytoma of the inferior nasal turbinate: A case report.

Int J Surg Case Rep 2021 Feb 27;79:409-412. Epub 2021 Jan 27.

Faculty of Medecine of Casablanca, Morocco.

Introduction: Glomangiopericytoma is defined as a sinonasal tumor with perivascular myoid phenotype, which was first described in 1942 by Stout and Murray as a soft tissue tumor with characteristic proliferation including branching vessels and small vessel perivascular hyalinization. The tumor accounts for less than 0.5 % of all sinonasal neoplasms. Read More

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February 2021

Granulomatosis with polyangiitis presenting as a solitary renal mass: A case report with imaging and literature review.

Radiol Case Rep 2021 Mar 17;16(3):736-741. Epub 2021 Jan 17.

Department of Radiology, Aichi Medical University, 1-1 Yazako Karimata, Yatomi City, Aichi 480-1195, Japan.

Granulomatosis with polyangiitis (GPA) manifests as necrotizing granulomatous inflammatory masses in the nasal cavity, paranasal sinuses, and lungs. However, a mass in the kidney is extremely rare. We herein report a case of GPA that presented as a solitary mass in the left kidney. Read More

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Invasive fungal disease misdiagnosed as tumour in association with orbital apex syndrome.

BMJ Case Rep 2021 Jan 20;14(1). Epub 2021 Jan 20.

Ophthalmology, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, India.

Invasive sino-orbital aspergillosis is a rare cause of orbital apex syndrome (OAS) in immunocompetent patients and often misdiagnosed as tumour because of its aggressive nature and invasive patterns. We report a 23-year-old immunocompetent man presenting with painful progressive loss of vision, ophthalmoplegia and proptosis of the right eye suggestive of OAS. MRI with gadolinium contrast showed an enhancing heterogeneous mass filling the paranasal sinuses, extraconal space and extending up to the right orbital apex. Read More

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January 2021

Radiation-induced intracranial osteosarcoma of the anterior skull base after treatment of esthesioneuroblastoma.

BMJ Case Rep 2021 Jan 18;14(1). Epub 2021 Jan 18.

Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA.

Esthesioneuroblastoma (ENB) is an uncommon sinonasal cancer of the olfactory neuroepithelium that is typically treated with surgical resection followed by radiation therapy. Radiation-induced intracranial osteosarcoma of the skull base is a rare but devastating long-term complication of radiation therapy in this region. Here, we present a case of an 82-year-old patient who developed radiation-induced osteosarcoma of the anterior skull base and paranasal sinuses 10 years after radiation therapy following resection of an ENB. Read More

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January 2021

Sinonasal inflammatory myofibroblastic tumour: a rare entity with diagnostic challenges.

BMJ Case Rep 2021 Jan 18;14(1). Epub 2021 Jan 18.

Department of Plastic Surgery, Christian Medical College, Vellore, India.

Inflammatory myofibroblastic tumour is a rare entity causing sinonasal involvement with variable behaviour. Mimicking various benign and malignant lesions, accurate diagnosis is often clinched on histopathology complemented with appropriate immunohistochemistry markers. Surgical resection is the main treatment modality with other forms of therapy reserved for unresectable lesions. Read More

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January 2021

Cyto-morphological and clinical approach to infections presenting with discharging sinuses mimicking malignancy.

Diagn Cytopathol 2020 Dec 17;48(12):1265-1272. Epub 2020 Aug 17.

Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Introduction: Discharging sinuses is a form of chronic unhealed infection that can present at any site due to a variety of infectious organisms. These discharging sinuses may be associated with mass lesions and lymphadenopathy to mimic some neoplastic processes. Identifying these infections with accuracy and promptness is essential, as the treatment regimens are specific. Read More

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December 2020

Evaluation of Inflammatory Blood Markers in Sinonasal Inverted Papilloma.

Ear Nose Throat J 2021 Jan 18:145561320988366. Epub 2021 Jan 18.

Department of Otolaryngology Head and Neck Surgery, Uludag University Medical Faculty, Bursa, Turkey.

Objective: Sinonasal inverted papillomas are benign neoplasms of the nasal cavity and paranasal sinuses. They have characteristic features such as a high risk of recurrence and possible malignant transformation. This study was conducted to investigate the relationship between sinonasal inverted papilloma and inflammatory blood markers. Read More

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January 2021

Spindle cell hemangioma of nasal passage and ethmoidal sinus in a 4-month old infant.

Arch Argent Pediatr 2021 02;119(1):e36-e40

Division of Pediatric Oncology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Spindle cell hemangioma (SCH) is a benign unusual vascular neoplasm. It does not have gender predilection and can occur at all ages. The disease affects dermis and subcutis of distal extremities predominantly; head and neck involvement is very rare, paranasal sinus involvement has not been reported before. Read More

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February 2021

Branchial cleft anomalies: hybrid "Branchial Inclusion" theory.

Eur Arch Otorhinolaryngol 2021 Jan 11. Epub 2021 Jan 11.

Department of Infectious Diseases, General Hospital Zadar, Bože Peričića 5, 23 000, Zadar, Croatia.

Purpose: Branchial cleft anomalies (BCAs) are developmental malformations of the head and neck region. Their histogenesis has been the subject of controversy and is not fully understood. This study aimed to test all present developmental theories ("branchial apparatus," "precervical sinus," "thymopharyngeal," and "inclusion" theories) on a sample of 48 BCAs from a single institution. Read More

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January 2021

The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series.

Sci Rep 2020 12 31;10(1):22444. Epub 2020 Dec 31.

Department of Neurosurgery, Medical Faculty, School of Medicine, Klinikum Rechts Der Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.

A variety of sinonasal tumours, meningiomas or other lesions of the anterior skull base involve the paranasal sinuses and the periorbital area. The transbasal approach (TBA) has turned out to be a feasible technique to reach those lesions. A retrospective review at a neurosurgical university department between November 2007 and January 2020 with adult patients who underwent resection of oncologic pathologies through TBA. Read More

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December 2020

Use of Silver Nitrate Application as Mini-Invasive Treatment of Pilonidal Sinus Disease.

Chirurgia (Bucur) 2020 Nov-Dec;115(6):775-782

Objectives: To investigate the cure rate and adverse effects of silver nitrate application for treatment of pilonidal sinus disease (PSD). Number of sinus pit orifices, and complications with silver nitrate application and debridement for sacrococcygeal PSD between January 2015 and July 2018 were analyzed in this retrospective study. Data were obtained from surgical, discharge, and outpatient follow-up records. Read More

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January 2021

Sinonasal teratocarcinosarcoma: a case report and literature review.

J Int Med Res 2020 Dec;48(12):300060520971488

Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.

Background: Sinonasal teratocarcinosarcoma (SNTCS) is a highly invasive malignant tumor most frequently found in the nasal cavity and paranasal sinuses. As a result, it can be confused with other sinonasal tumors. In addition, SNTCS progresses rapidly and often infiltrates other tissues or organs in the early phase, resulting in poor patient prognosis. Read More

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December 2020

[Treatment of adenoid cystic carcinoma of sphenoid sinus with lung metastasis by arotinib: a case report].

Z J Xu M Zhou

Zhonghua Zhong Liu Za Zhi 2020 12;42(12):1054-1055

Department of Oncology, Qingdao Municipal Hospital, Qingdao 266000, China.

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December 2020

Aggressive resection of craniopharyngioma achieved by drilling the tuberculum sellae/planum sphenoidale using a frontal basal interhemispheric approach: A review of 55 cases.

J Clin Neurosci 2021 Jan 14;83:13-20. Epub 2020 Dec 14.

Department of Clinical Laboratory Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: The frontal basal interhemispheric approach (FBIA) is preferable for resection of craniopharyngioma (CP), achieving desirable total resection rates in early reports of lesions located in the suprasellar region to the third ventricle. For tumours that have created a larger obstruction of the tuberculum sellae and planum sphenoidale, aggressive resection in the intrasellar region and medial wall of the cavernous sinus is not feasible compared to improving tumour visualization by drilling the tuberculum sellae and planum sphenoidale. In a report of drilling the sellar tuberculum and sphenoid planum, drilling allowed the direct visualization of tumours invading the intrasellar region and medial wall of the cavernous sinus. Read More

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January 2021