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J Oral Maxillofac Surg 2019 Mar 26. Epub 2019 Mar 26.

Oral and Maxillofacial Surgery Attending, University of Florida College of Dentistry, Gainesville, FL.

Purpose: To describe and discuss the demographic and clinical features of oral melanomas, which are relatively rare but deadly neoplasms, and list the criteria for their diagnosis to increase early detection.

Materials And Methods: An institutional review board-approved retrospective search of oral melanomas was performed in the archives of the University of Florida Oral and Maxillofacial Pathology Biopsy Service (Gainesville, FL) from 2015 through 2018. Exclusion criteria included cases with inconclusive diagnosis, skin involvement, and missing clinical data or slide material. Read More

J Oral Maxillofac Pathol 2019 Feb;23(Suppl 1):27-31

Department of Oral Pathology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India.

The presence of numerous minor salivary gland tissues in the posterior part of hard palate increases the possibility of salivary gland neoplasms. Minor salivary gland tumor accounts for about 15% of all the salivary gland neoplasms, of which mucoepidermoid carcinoma (MEC) accounts for about 35.9%. Read More

J Oral Maxillofac Pathol 2019 Feb;23(Suppl 1):7-11

Department of Oral and Maxillofacial Pathology and Microbiology, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India.

Lymphomas are a group of malignant blood cell tumors that develop from lymphocytes representing 2.2% of all malignant neoplasms of the head and neck. Two main categories of lymphomas are Hodgkin's lymphoma and non-Hodgkin's lymphoma (NHL) of which 90% are of the NHL type. Read More

Case Rep Dent 2019 27;2019:7416302. Epub 2019 Feb 27.

Division of Oral & Maxillofacial Surgery, John H. Stroger Hospital of Cook County, Chicago, IL, USA.

Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor, with a limited number of published reports. Less than three hundred cases have been reported in the literature and only 18 of these cases have been reported in minor palatal salivary glands, though publication bias is likely a factor. We present a case of a 57-year-old male who was diagnosed with MASC tumor presenting in a minor salivary gland and briefly review the current literature. Read More

Am J Case Rep 2019 Mar 30;20:412-418. Epub 2019 Mar 30.

School of Medicine and Health Sciences, Tecnologico de Monterrey, Guadalajara, Jalisco, Mexico.

BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical presentation includes fever, weight loss, nasal obstruction, epistaxis, nasal or facial edema, as well as necrotic ulcers in the nasal cavity, gums, and palate. It has been found to have an important association with the Epstein-Barr virus. Read More

Digit J Ophthalmol 2018 18;24(1):1-5. Epub 2018 Feb 18.

Department of Ophthalmology, Rhode Island Hospital, Providence, Rhode Island.

Adenoid cystic carcinoma (ACC) is a rare neoplasm of secretory epithelium that most commonly occurs in the fifth and sixth decades of life. It is characterized by high recurrence rates and poor response to chemotherapy, In the orbit, ACC usually presents as a lacrimal gland mass. We describe the rare case of a 70-year-old woman who presented with pain during mastication and bilateral facial numbness in the cranial nerve V2 distribution. Read More

Oral Dis 2019 May 5;25(4):1084-1090. Epub 2019 Mar 5.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Objective: Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self-limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. Read More

Int J Pediatr Otorhinolaryngol 2019 May 10;120:93-99. Epub 2019 Feb 10.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02115, United States. Electronic address:

Introduction: Mucoepidermoid carcinoma is a rare malignant salivary gland neoplasm in the pediatric population. Few studies have discussed best practice with respect to diagnosis and treatment in children.

Objective: To present our institution's experience with the evaluation and management of pediatric mucoepidermoid carcinoma of the head and neck. Read More

Indian Pediatr 2018 Dec;55(12):1087-1088

Samayan Hospital, Varanasi, Uttar Pradesh, India.

Background: Neonatal respiratory distress due to coexisting subglosso-palatal membrane and tongue dermoid has not been reported yet.

Case Characteristics: A newborn with respiratory distress having a membrane in the oral cavity. Excision of membrane revealed a tongue mass with cleft palate, obstructing the nasopharynx completely. Read More

Cancer Imaging 2019 Jan 31;19(1). Epub 2019 Jan 31.

Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth Peoples Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China.

Background: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.

Methods: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed. Read More

Indian J Cancer 2018 Jul-Sep;55(3):292-296

Department of Pathology, A.H. Regional Cancer Centre, Cuttack, Odisha, India.

Background: : Malignant melanoma is a tumor of melanocytic origin. Although uncommon in India as compared with the west, its prevalence is increasing.

Objectives: To document the pattern of clinicopathological features of malignant melanoma cases attending in a regional cancer center in eastern India. Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):1970-1972

Dept. of Oral and Maxillofacial Surgery, National Hospital Organization Hamada Medical Center.

Oral leukoplakia is the most common premalignant or potentially malignant lesion in the oral mucosa. This retrospective study examined 67 lesions from 62 patients with clinical diagnoses of oral leukoplakia who underwent surgical excision in our department from 2015 to 2017. The patients comprised 22 men and 40 women. Read More

Case Rep Dent 2018 25;2018:2052347. Epub 2018 Dec 25.

New York University College of Dentistry, 345 E 24th St, Room 837, NY, New York 10010, USA.

Introduction: Salivary gland tumors are relatively common in the junction of the hard and soft palate area of the oral cavity. Pleomorphic adenoma is considered the most common benign salivary gland tumor in this location. Some of the rarer subtypes of this tumor may have a misleading clinical presentation. Read More

Eur Radiol 2019 Jan 16. Epub 2019 Jan 16.

Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.

Objectives: This study compares reduction of strong metal artifacts from large dental implants/bridges using spectral detector CT-derived virtual monoenergetic images (VMI), metal artifact reduction algorithms/reconstructions (MAR), and a combination of both methods (VMI) to conventional CT images (CI).

Methods: Forty-one spectral detector CT (SDCT) datasets of patients that obtained additional MAR reconstructions due to strongest artifacts from large oral implants were included. CI, VMI, MAR, and VMI ranging from 70 to 200 keV (10 keV increment) were reconstructed. Read More

J Cancer Res Clin Oncol 2019 Apr 11;145(4):851-859. Epub 2019 Jan 11.

Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Yanagido, Gifu, 501-1193, Japan.

Purpose: Cleft palate transmembrane protein 1 (Clptm1) and its paralog protein, Cisplatin resistance-related protein 9 (CRR9) constitute a highly conserved protein family, from Caenorhabditis elegans to Homo sapiens. In the present study, we examined the clinicopathological and biological significance of Clptm1 and CRR9 expression in oral squamous cell carcinoma (OSCC).

Methods: Ninety-eight OSCC tissue specimens were immunohistochemically stained with specific antibodies to Clptm1 and CRR9. Read More

Niger Postgrad Med J 2018 Oct-Dec;25(4):246-251

Department of Oral and Maxillofacial Surgery/Oral Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria.

Background: Orofacial malignancy is a growing health issue common in developing regions of the world. Presentation patterns are myriad with geographic variations. Advanced stage owing to late presentation constitutes a significant public health burden. Read More

Diagn Pathol 2018 Dec 22;13(1):99. Epub 2018 Dec 22.

Department of Pathology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.

Background: Epignathus is a rare congenital orofacial teratoma infrequently associated with intracranial extension. Intracranial extension of an epignathus indicates a poor prognosis; however, only a small number of such cases have been reported. While there have been some studies reporting cases of epignathus expanding directly into the cranium, others have reported no communication between an epignathus and an intracranial tumor. Read More

Niger J Clin Pract 2018 Dec;21(12):1674-1677

Department of Oral and Maxillofacial Pathology/Biology, Lagos University Teaching Hospital, Lagos, Nigeria.

Squamous papillomas are common lesions of the oral mucosa. They are benign proliferating lesions often painless, slow growing and with a cauliflower appearance. However, its clinical appearance which sometimes mimics exophytic carcinoma, verrucous carcinoma or condyloma acuminatum raises concern when it occurs in the oral cavity. Read More

Ochsner J 2018 ;18(4):345-350

Department of Pediatric Dentistry, Medical University of South Carolina, James B. Edwards College of Dental Medicine, Charleston, SC.

Background: Tooth agenesis, the congenital absence of one or more teeth, can be diagnosed in children in the first decade of life. Tooth agenesis is a phenotypic feature of conditions such as ectodermal dysplasia, cleft lip, cleft palate, Down syndrome, and Van der Woude syndrome. Tooth agenesis can also be nonsyndromic. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1832-1833

A 41 year old female complained of left eyelid, cheek and face erythema, swelling with pain for 7 days. She was diagnosed with cervical squamous cell carcinoma, stage ⅢA a year ago. The anterior rhinoscopy examination showed that the dry scab adheres to the left nasal cavity, and a small amount of reddish mass were found, and the touch was brittle. Read More

Clin Otolaryngol 2018 Nov 30. Epub 2018 Nov 30.

Otorhinolaryngology-Head and Neck Surgery Department, Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Galicia, Spain.

Oral Maxillofac Surg Clin North Am 2019 Feb;31(1):125-144

Division of Oral and Maxillofacial Surgery, University of Texas Southwestern Medical School, Parkland Memorial Hospital, 5323 Harry Hines Boulevard, Mail Code 9109, Dallas, TX 75390, USA.

Salivary gland tumors are rare pathologic entities that are derived from major and minor salivary gland tissue located throughout the head and neck region. These tumors are distinctly heterogenous, comprising numerous cell types, especially those deemed malignant. The incidence of malignant salivary gland tumors is widely distributed in both adult and pediatric patient populations. Read More

J Craniofac Surg 2019 Jan;30(1):211-213

Department of Plastic and Reconstructive Surgery, Toho University Omori Medical Center, Tokyo, Japan.

Background: In primary reconstruction after maxillectomy for cancer, simple and less invasive surgical techniques considering functionality and aesthetics are necessary. The authors performed reconstruction for tissue defects after maxillectomy using an Ultra flex mesh plate and a free rectus abdominis myocutaneous flap including the aponeurosis of the external abdominal oblique muscle.

Method: A 72-year-old male with a maxillary squamous cell carcinoma underwent subtotal maxillectomy. Read More

Prim Dent J 2018 Sep;7(3):38-41

Gorlin-Goltz syndrome encompasses a variety of clinical signs and symptoms including important oral manifestations which general dental practitioners should be aware of. In light of the risk of malignancy it is important to be aware of this syndrome and recognise the need for early referral for multidisciplinary management. This paper aims to discuss Gorlin-Goltz syndrome, the pathophysiology of the condition and address the wide range of clinical manifestations. Read More

Facial Plast Surg Clin North Am 2019 Feb;27(1):105-118

Kellogg Eye Center, Michigan Medicine, 1000 Wall Street, Ann Arbor, MI 48105, USA.

Options for periorbital reconstruction include primary wound closure, local flaps, regional/distant flaps, or full-thickness skin grafts. Optimal aesthetic and functional outcomes are achieved by assessing regional contours, skin type, and facial aesthetic units. Like tissue should replace like tissue; for example, skin with skin, tarsus with tarsus (or equivalent material, eg, hard palate, ear cartilage, or autologous substitute), and conjunctiva with mucous membrane or like substitute (buccal mucous membrane, amniotic membrane). Read More

World Neurosurg 2019 Feb 1;122:196-202. Epub 2018 Nov 1.

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: A persistent craniopharyngeal canal (PCC) is a rare cause of cerebrospinal fluid rhinorrhea in children. The condition often coexists with other midline facial defects, such as cleft palate. Children with PCC may also have pituitary dysfunction or neoplasms, such as craniopharyngiomas within the canal. Read More

Pan Afr Med J 2018 19;30:141. Epub 2018 Jun 19.

Service de Radiothérapie, CHU Hassan II-Fès, Maroc.

NK/T-cell lymphoma is a severe and rare disorder in Africa and in Europe. Treatment is based on radiotherapy and chemotherapy. We here report two cases of elderly patients aged 55 years and 52 years, respectively, with bilateral nasal obstruction associated with purulent rhinorrhea. Read More

Open Dent J 2018 28;12:782-790. Epub 2018 Sep 28.

Department of Pathology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, India.

Objective: Fine Needle Aspiration Cytology (FNAC) is a rapid, reliable and safe diagnostic tool used for various lesions of the oral cavity and salivary glands. The present study was undertaken to categorize the cytomorphology of the oral cavity and salivary gland lesions on FNAC and to assess the accuracy of FNAC in arriving at a diagnosis.

Materials And Methods: A prospective study on oral cavity swellings and salivary gland aspirates was done during a 2 year period from August 2015 to July 2017 in which a total of 70 FNAC's were performed. Read More

BMJ Open 2018 Oct 18;8(10):e019505. Epub 2018 Oct 18.

Faculty of Pharmaceutical Sciences, State University of Campinas, Sao Paulo, Brazil.

Introduction: Oral mucositis is an iatrogenic condition of erythematous inflammatory changes which tends to occur on buccal and labial surfaces, the ventral surface of the tongue, the floor of the mouth and the soft palate of patients receiving chemotherapy. This protocol of ongoing randomised parallel group clinical trial aims to access the therapeutic effect of an herbal gel containing 2.5% Verlot standardised extract on oral mucositis in patients with head and neck cancer compared with low-level laser therapy. Read More

Eur Arch Otorhinolaryngol 2019 Jan 17;276(1):263-265. Epub 2018 Oct 17.

Department of Otorhinolaryngology, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

Purpose: Sigmund Freud, the father of modern psychoanalysis, suffered from what was considered to be a malignant tumour spreading from the back of his palate. He underwent numerous surgical interventions and radiation therapy over the course of 16 years. Such a long survival casts a shadow of doubt on the diagnosis of oral cancer that was given to Freud. Read More

Fam Cancer 2019 Apr;18(2):253-260

Laboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz Barmherzige Schwestern, Seilerstätte 4, 4010, Linz, Austria.

Hereditary diffuse gastric cancer (HDGC) is an autosomal-dominantly inherited cancer syndrome associated with a high risk for diffuse gastric and lobular breast cancer, caused by heterozygous CDH1 germline mutations. Of note, also cleft lip/palate (CLP) has been described in few HDGC families. Here we report on an extensive pedigree presenting with HDGC, CLP and a CDH1 splice site mutation (c. Read More

Contemp Clin Dent 2018 Sep;9(Suppl 2):S365-S368

Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Aurangabad, Maharashtra, India.

Clinicians come across cases of palatal swellings that present with ambiguous features. They may vary in their etiology from numerous infectious and noninfectious causes to a wide array of neoplasms. Accurate diagnosis of such lesions is vital for their prompt and precise management. Read More

Spec Care Dentist 2018 Nov 5;38(6):438-444. Epub 2018 Oct 5.

Professor Edgard Santos Hospital, Federal University of Bahia, Salvador, Bahia, Brazil.

Primary manifestations of extraganglion non-Hodgkin lymphoma (NHL) from T-cells in the oral cavity are rare and often difficult to diagnose. Herein, we describe a case of T-cell NHL with a primary lesion on the lip diagnosed with a 25-year-old woman. The patient reported the appearance of the initial lesion on the upper lip, which advanced to the hard palate and oral mucosa. Read More

Drug Des Devel Ther 2018 21;12:3095-3106. Epub 2018 Sep 21.

Department of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China,

Background: Nowadays, the combination of microRNA (miR) is attracting increased attention in clinical cancer trials. However, the clinical use of miR is highly limited because of certain properties such as instability, low-specificity distribution, and metabolic toxicity.

Methods: In order to improve the anti-tumor efficacy and reduce the side effects of miR in treating melanoma, a combination of graphene oxide (GO), chitosan (CS), and a cellular penetrating peptide, MPG, was prepared with solid dispersion method in this research. Read More

Anticancer Res 2018 Oct;38(10):5811-5817

Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, University of Basel, Basel, Switzerland.

Background/aim: Hard palate melanoma is an extremely rare and aggressive tumor arising from the mucosal epithelium of the oral cavity. The aim of this study was to analyze epidemiology, loco-regional treatment patterns and survival outcomes of this disease.

Materials And Methods: The National Cancer Institute's Surveillance Epidemiology and End Results (SEER) database was searched for all cases of hard palate melanoma diagnosed between 1973 and 2012. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Jan 17;127(1):62-70. Epub 2018 Aug 17.

Division of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, Gainesville, FL, USA.

Background: Glomus tumors are benign neoplasms that most commonly present in the subungual region. Their occurrence in the oral cavity is exceedingly rare. Here, we present 2 cases from the oral cavity, detail their clinical and histopathologic features, and review the literature for solitary cases involving the oral regions. Read More

World Neurosurg 2018 Dec 13;120:e1011-e1016. Epub 2018 Sep 13.

Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Chinese Medical Association Neuroendoscopic Training Base and Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China. Electronic address:

Background: Both the pterygopalatine fossa (PPF) and the infratemporal fossa (ITF) lie outside the midline of the skull base. Lesions in the PPF or ITF include trigeminal schwannoma (trigeminal schwannoma, TS), which originates from the second or third branch of the trigeminal nerve (maxillary nerve or mandibular nerve). Due to their typically deep anatomic location, lesions in the PPF or ITF can be difficult to treat using traditional surgical approaches. Read More

BMJ Case Rep 2018 Sep 8;2018. Epub 2018 Sep 8.

Instituto Português de Oncologia Lisboa Francisco Gentil, Radiology Department, Lisboa, Portugal.

We report the case of a 74-year-old man with a giant cell tumour (GCT) of the right maxilla and pterygoid process. The patient presented to the maxillofacial and head and neck surgery clinic with an ulcerated lesion of the hard palate. Initial workup with CT revealed a mass within the right maxillary sinus and pterygoid process with associated bone expansion and erosion. Read More

J Coll Physicians Surg Pak 2018 Sep;28(9):S187-S189

Department of Oral Surgery, Manipal College of Dental Sciences (MCDS), Mangalore, Karnataka, India.

Oral mucosal melanoma is rare and more aggressive than cutaneous melanoma. Hard palate and maxillary alveolar crest are most commonly involved. Multidisciplinary team approach is necessary for successful management of this tumor. Read More

Neurologist 2018 Sep;23(5):152-154

Division of Critical Care Neurology.

Introduction: Elsberg syndrome (ES) is a rarely recognized cause of cauda equina syndrome and lower thoracic myelitis, mainly linked to reactivation, or occasionally primary, infection with herpes simplex virus type 2. West Nile virus neuroinvasive disease is rarely considered in the differential diagnosis of patients with ES.

Case Report: A 63-year-old man with pancreatic cancer in remission and polymyalgia rheumatica on low-dose prednisone presented with a 10-day history of low-back pain and a viral-type illness with low-grade fever, nausea, and vomiting. Read More

J Am Acad Dermatol 2019 Apr 20;80(4):1133-1135. Epub 2018 Aug 20.

Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio. Electronic address:

J Vet Med Sci 2018 Oct 16;80(10):1511-1514. Epub 2018 Aug 16.

Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

A hard palate mass was surgically removed from an Australian green tree frog (Litoria caerulea) and examined pathologically. The tumor consisted of sheets of small cells arranged in a tubular structure and cords or rosettes with fibrovascular stroma. Immunohistochemically, neoplastic cells were diffusely positive for cytokeratin and neuron-specific enolase and partially positive for S-100 and doublecortin. Read More

World J Surg Oncol 2018 Aug 13;16(1):167. Epub 2018 Aug 13.

Department of Pharmacy, Guiyang University of Chinese Medicine, Guiyang, 550025, People's Republic of China.

Background: Safflower polysaccharide (SPS) is one of the most important active components of safflower (Carthamus tinctorius L.), which has been confirmed to have the immune-regulatory function and antitumor effect. This study aimed to explore the effects of safflower polysaccharide (SPS) on tongue squamous cell carcinoma (TSCC). Read More

J Dent (Tehran) 2018 May;15(3):187-192

Associate Professor, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Prosthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

This article describes the prosthetic treatment of a patient suffering from a hemimaxillary defect after surgical resection of an adenoid cystic carcinoma (ACC) in the palate. The patient had also received therapeutic irradiation. One year after radiotherapy, three implants were placed in the remaining maxillary bone without any bone augmentation. Read More

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Aug;53(8):533-538

Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.

To investigate the clinicopathologic and molecular genetic features of secretory carcinoma of salivary gland (SCSG). Six cases of SCSG were collected from Zhejiang Provincial Peoples Hospital from January 2011 to March 2018. The clinical, histopathological and immunohistochemical features were analyzed and fluorescence in situ hybridization (FISH) was used to detect ETV6 gene rearrangement. Read More

Expert Rev Hematol 2018 09 21;11(9):737-748. Epub 2018 Aug 21.

a Department of Pathology , Assiut University Hospitals , Assiut , Egypt.

Introduction: Non-Hodgkin lymphomas of the oral and maxillofacial regions are uncommon malignancies. They usually have progressive course and dismal outcome. Areas covered: This review provides an update about the clinicopathologic, immunophenotypic, and molecular features of these lymphomas. Read More

Facial Plast Surg 2018 Aug 24;34(4):389-393. Epub 2018 Jul 24.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Harvard University, Boston, Massachusetts.

Combination anterior palatectomy and rhinectomy defects result in complete loss of midface and nasal support and present a significant reconstructive challenge. A novel use of the scapular tip free flap-the tip-on-tip scapula flap-was developed to provide both palatal repair and restoration of intrinsic nasal support. The scapular tip bone is split into a large proximal segment for the anterior palate and a smaller distal bone segment for nasal framework reconstruction. Read More

Indian J Ophthalmol 2018 08;66(8):1218-1220

Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm composed of basaloid epithelial and myoepithelial cells. The palate is the most commonly involved intraoral site for ACC. Here, we document the case of an advanced ACC arising from the hard palate that presented with right-sided sixth nerve palsy in a 75-year-old male with no other systemic illnesses. Read More

Ear Nose Throat J 2018 Jul;97(7):193-194

Department of Otolaryngology-Head and Neck Surgery, Wake Forest Baptist Medical Center, Winston Salem, NC, USA.

Indian J Pathol Microbiol 2018 Jul-Sep;61(3):397-398

Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, Haryana, India.

Salivary gland tumors are clinically diverse group of neoplasms, of which pleomorphic adenoma and mucoepidermoid carcinoma (MEC) are most common benign and malignant tumors, respectively. Besides the major salivary glands, these tumors can affect the minor salivary gland tissues in the posterior part of the hard palate. Minor salivary gland tumor accounts for about 15% of all the salivary gland neoplasm, of which MEC accounts to about 35. Read More