6,319 results match your criteria Malignant Tumors of the Nasal Cavity

Sinonasal Renal Cell-Like Adenocarcinoma.

Cureus 2021 Apr 4;13(4):e14285. Epub 2021 Apr 4.

Otolaryngology - Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA.

Sinonasal renal cell-like adenocarcinoma (SNRCLA) is a newly defined, rare malignant tumor of the nasal cavity. The clinical course and response to treatment remain uncertain. The purpose of this study is to report a new case of SNRCLA and review the literature to determine clinical characteristics, treatment options, and outcomes. Read More

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Sinonasal Extramedullary Plasmacytoma With Rare Osteolytic Lesions.

Cureus 2021 Mar 31;13(3):e14220. Epub 2021 Mar 31.

Orthopedics, General Hospital of Patras, Patras, GRC.

Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate either from bone or soft tissue and could be primary or a part of a systemic process during the course of multiple myeloma. Extramedullary plasmacytomas (EPs) in the sinonasal tract or nasopharynx are rare and mostly presented as case reports. Read More

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Bilateral Sinonasal Inverted Papilloma: Report of an Uncommon Case Involving Sinuses of the Face and Orbital Cavity.

Am J Case Rep 2021 May 2;22:e929910. Epub 2021 May 2.

Department of Oral Pathology, School of Dentistry, Federal University of Pará, Belém, PA, Brazil.

BACKGROUND Nasosinusal papilloma is a benign aggressive tumor. It usually occurs unilaterally in the nasal cavity and can extend to the sinuses. The diagnosis is made by the correlation of findings observed in tomographic and histopathological exams. Read More

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Primary Cutaneous Solitary Fibrous Tumor on the Back.

Ann Dermatol 2020 Apr 11;32(2):155-158. Epub 2020 Mar 11.

Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea.

Solitary fibrous tumors (SFT) are uncommon mesenchymal tumors. SFT have several synonyms including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, and submesothelial fibroma. SFT usually occur in the pleura or other serosal surfaces, but SFT can also develop in extrapleural areas including the nasal cavity, orbit, retroperitoneum, and pelvis. Read More

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Mucosal resurfacing of the suprastructure maxillectomy cavity using nasal cavity mucosa flaps.

Oral Oncol 2021 Apr 25:105289. Epub 2021 Apr 25.

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea. Electronic address:

Objective: We analyzed clinical data of patients in which the suprastructure maxillectomy site was covered with nasal cavity mucosa flaps with or without free mucosa graft from the nasal septum, to determine the usefulness of this procedure.

Patients And Methods: A total of four edentulous patients who had the suprastructure maxillectomy site covered using nasal cavity mucosa flaps with or without free mucosa graft from the nasal septum between 2014 and 2020, were analyzed.

Results: All patients underwent suprastructure maxillectomy using the external approach. Read More

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Clinical, anatomopathological, and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog.

Open Vet J 2021 Jan-Mar;11(1):1-5. Epub 2021 Jan 3.

Department of Veterinary Medicine, University of Vila Velha, Vila Velha, Brazil.

Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region. Some malignant nasal cavity neoplasms may invade the brain causing clinical neurological signs, as well as purulent nasal secretion and epistaxis.

Case Description: A case of neoplasm is reported in a 14-year-old pincher presenting dyspnea, epistaxis, and neurological alterations. Read More

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January 2021

Solitary extramedullary plasmacytoma presenting as an adrenal tumor: case report and literature review.

Gland Surg 2021 Mar;10(3):1158-1164

Department of General Surgery, The Third Xiangya Hospital of Central South University, Changsha, China.

Solitary extramedullary plasmacytoma, an extremely rare case which accounts for about 3% of all plasma cell neoplasms, often occurs in the head and neck region such as para nasal sinuses, nasal cavity and oral cavity, it also occurs in the lymph nodes, lungs, thyroid, intestine, liver, pancreas, testis, breast, or skin. Isolated primary plasmacytoma of adrenal is extremely rare and only nine documented cases have been reported in the literature. We are presenting the 10 case which is the youngest patient until now with symptoms of fever and hepatosplenomegaly. Read More

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[Free anterolateral thigh flap with superficial temporal vessels as recipient vessels for reconstruction of defect after maxillectomy in malignant tumor].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;56(4):369-373

Department of Oral and Maxillofacial Surgery, the Second Xiangya Hospital of Central South University, , Changsha 410011, China.

To study the effects of superficial temporal artery and vein as recipient vessels for the free anterolateral thigh flap on the appearance and functions after maxillectomy. Clinical data of 21 patients with malignant maxillary tumors in Department of Oral and Maxillofacial Surgery, the Second Xiangya Hospital of Central South University from January 2014 to November 2019, who were treated by free anterolateral thigh flap with temporal superficial vessels as the recipient vessels were analyzed retrospectively. There were 18 males and 3 females, with the age ranging from 29 to 73 years old, including 19 cases of squamous carcinoma, 1 case of adenoid cystic carcinoma and 1 case of osteosarcoma. Read More

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[Diagnosis and surgical treatment of sinonasal phosphaturic mesenchymal tumor].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;56(4):351-355

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai JiaoTong University Affiliated Sixth People's Hospital, Shanghai 200233, China.

To investigate the diagnosis and surgical treatment of sinonasal phosphaturic mesenchymal tumor (PMT). The medical records of nine patients who had been diagnosed as sinonasal PMT in Department of Otorhinolaryngology Head and Neck Surgery, Shanghai JiaoTong University Affiliated Sixth People's Hospital between January 2015 and May 2020 were collected, including 4 males and 5 females, ranging from 36 to 59 years. The patient's previous history, clinical manifestations, imaging findings, laboratory results, surgical procedure, pathological results and postoperative follow-up data were analyzed by descriptive statistical analysis. Read More

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Incidental finding of metastatic malignancy involving the sphenoid sinus on a cone-beam computed tomographic scan: A case report.

Imaging Sci Dent 2021 Mar 28;51(1):87-90. Epub 2021 Jan 28.

Department of Oral and Maxillofacial Pathology, Radiology and Medicine, New York University College of Dentistry, New York, NY, USA.

The increased use of cone-beam computed tomographic (CBCT) scans has made it increasingly necessary to evaluate incidental findings on CBCT scans. This report describes the case of a 66-year-old female patient who presented to the Department of Oral and Maxillofacial Pathology, Radiology and Medicine at the College of Dentistry of the author's institution and underwent a CBCT scan for maxillary alveolar process implant planning. Upon evaluation of the CBCT scan, a radiopaque (soft tissue attenuation) mass in the left superior aspect of the nasal cavity and left locule of the sphenoid sinus with opacification of the left locule of the sphenoid sinus was incidentally noted. Read More

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Case Report: SMARCB1 (INI-1)-Deficient Carcinoma of the Nasal Cavity with Pure Yolk Sac Tumor Differentiation and Elevated Serum AFP Levels.

Onco Targets Ther 2021 29;14:2227-2233. Epub 2021 Mar 29.

Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, 110001, People's Republic of China.

In adults, yolk sac tumors (YSTs) in the nasal cavity and paranasal sinuses are very rare. To date, only six cases have been reported in the English literature. YSTs in adults are often accompanied by cancer, teratocarcinosarcoma, and other malignant components. Read More

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[Clinical analysis of 31 cases of esthesioneuroblastoma].

Xindi He Ying Wang

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;35(4):338-340

Department of Rhinology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052,China.

To investigate the clinical characteristics and prognostic factors of esthesioneuroblastoma. The clinical data of 31 patients with esthesioneuroblastoma were retrospectively studied. The average time from first onset to diagnosis in 31 patients was 7. Read More

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[Diagonistic and prognostic analysis of olfactory neuroblastoma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;35(3):224-228

Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of Qingdao University,Qingdao,266003,China.

To explore the therapeutic effect and prognostic risk factors of olfactory neuroblastoma. Retrospective analysis of clinical data of 31 patients with olfactory neuroblastoma. The Kaplan-Meier method was used for survival analysis to calculate the overall survival rate and progress-free survival rate. Read More

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Radiotherapy as Part of Treatment Strategies in Nasal Cavity and Paranasal Sinus Malignancies.

Anticancer Res 2021 Mar;41(3):1587-1592

Radiation Oncology, University Hospital of Munster, Munster, Germany.

Background/aim: Modern intensity-modulated radiotherapy (IMRT) is frequently applied to treat patients with nasal cavity and paranasal sinus (NC/PNS) malignancies.

Patients And Methods: One hundred and four patients who underwent radiotherapy (RT) between 1994 and 2020 were recognized. This analysis compared conventional-radiotherapy (CRT) and image-guided IMRT outcomes for NC/PNS malignancies. Read More

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[Follow-up care of sinonasal papillomas - risk factors for recurrence and malignant progression].

Laryngorhinootologie 2021 04 30;100(4):261-269. Epub 2021 Mar 30.

Klinik für Hals-Nasen-Ohrenheilkunde, KRH-Klinikum Nordstadt, Hannover, Germany.

Objective: Sinonasal papillomas are tumors of the nasal cavity and paranasal sinuses. They are treated through complete resection under oncologic conditions. Two characteristics complicate follow-up: 1) frequent tumor recurrences (even many years after initial diagnosis), 2) possibility for malignant progression. Read More

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NK/T-cell lymphoma of the nasal cavity: an unexpected diagnosis.

BMJ Case Rep 2021 Mar 24;14(3). Epub 2021 Mar 24.

Department of Otolaryngology/ Head and Neck Surgery, University Hospital Waterford, Waterford, Republic of Ireland.

Nasal-type Natural Killer/T-cell Lymphoma (NKTL) is a rare form of extranodal non-Hodgkin's lymphoma, typically arising in the nasopharynx and displaying an aggressive and ultimately fatal clinical course. The disease is linked to Epstein-Barr virus infection and is endemic to Asia and South America, but extremely few cases have been reported in Europe. We present two cases of nasal NKTL unexpectedly diagnosed in elderly patients, following very different presentations to our otolaryngology service. Read More

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Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis.

Glycobiology 2021 Mar 20. Epub 2021 Mar 20.

Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21287, USA.

Siglec-8, an immune-inhibitory sialoglycan binding lectin (S8), is expressed on the surface of eosinophils and mast cells, potent mediators of allergic inflammation. When S8 engages endogenous sialoglycan ligands, eosinophils undergo apoptosis and mast cell mediator release is inhibited. In the human airway, Siglec-8 ligands (S8L) are sialylated keratan sulfate chains carried on isoforms of the protein Deleted in Malignant Brain Tumors-1 (DMBT1), an immunoregulatory protein that we recently identified as the endogenous ligand for S8, DMBT1S8. Read More

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Palatal flap in bilateral inferior partial maxillectomy.

BMJ Case Rep 2021 Mar 16;14(3). Epub 2021 Mar 16.

Department of Dental and Oral Surgery, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.

Maxillectomy is done for a variety of disease conditions. Reconstruction following maxillectomy is done to restore the form and function. One of the important goals that are to be achieved in reconstruction is the separation of the oral and nasal cavities. Read More

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Sustained remission of multi-line relapsed extranodal NK/T-cell lymphoma, nasal type, following sintilimab and chidamide: A case report.

Medicine (Baltimore) 2021 Mar;100(10):e24824

Department of Hematology.

Introduction: There is currently no optimal treatment modality for refractory or relapsed Extranodal NK/T-cell lymphoma, nasal type (ENKTL). In recent years, programmed cell death protein 1 (PD-1)/programmed cell - ligand 1 pathway blockade and histone deacetylase inhibitors have emerged as promising strategies for refractory or relapsed ENKTL. Accumulating evidence has shown that therapeutic effects of anti-PD-1 antibody could be enhanced by histone deacetylase inhibitors. Read More

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Surgical Debulking and TransEndoscopic Noncontact Diode Laser Application for Treating a Sinonasal Myxoma in a Horse.

J Equine Vet Sci 2021 03 16;98:103354. Epub 2020 Dec 16.

Unit of Equine Medicine and Surgery, Veterinary Teaching Hospital, Faculty of Veterinary Medicine of the University of Teramo, Italy.

Equine sinonasal myxomas (SNM) are very rare; only a few cases/small case series are reported in veterinary literature. The purpose of this report is to describe the diagnostic and surgical procedure adopted to approach the neoplastic mass in a case of equine SNM. A 5 year old, Murgese gelding was presented with mild serous nasal discharge, minimal facial swelling, decreased airflow from the right nostril, and dull frontal sinus percussion. Read More

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Dynamic evaluation of the prognostic value of F-FDG PET/CT in extranodal NK/T-cell lymphoma, nasal type.

Ann Hematol 2021 Apr 26;100(4):1039-1047. Epub 2021 Feb 26.

Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

Extranodal natural killer/T-cell lymphoma, nasal-type (ENKTL) is a type of rare and distinct entity of non-Hodgkin lymphoma with poor prognosis. It is important to evaluate the early treatment response accurately to decide further treatment strategy. F-FDG PET/CT plays an important role in response evaluation and prognostic prediction in some kinds of lymphomas. Read More

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Comparison of CT features of 79 cats with intranasal mass lesions.

J Feline Med Surg 2021 Feb 19:1098612X21994396. Epub 2021 Feb 19.

Diagnostic Imaging, University of Glasgow School of Veterinary Medicine, Glasgow, UK.

Objectives: This retrospective multicentre study compared the CT characteristics of cats diagnosed with intranasal mass lesions to determine if defining imaging features exist between different tumour types and between neoplastic and non-neoplastic lesions.

Methods: The medical records of two institutions were reviewed for cats with CT findings consistent with an intranasal mass lesion with subsequent histopathological examination. For each CT scan the mass location, growth pattern, margin distinction, contrast enhancement pattern and presence of intralesional areas of mineralisation or necrosis were recorded. Read More

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February 2021

Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.

Lancet Oncol 2021 03 15;22(3):381-390. Epub 2021 Feb 15.

Department of Otolaryngology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou Key Laboratory of Otorhinolaryngology, Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, China; Department of Otolaryngology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:

Background: The role of surgery compared with reirradiation in the primary treatment of patients with resectable, locally recurrent nasopharyngeal carcinoma (NPC) who have previously received radiotherapy is a matter of debate. In this trial, we compared the efficacy and safety outcomes of salvage endoscopic surgery versus intensity-modulated radiotherapy (IMRT) in patients with resectable locally recurrent NPC.

Methods: This multicentre, open-label, randomised, controlled, phase 3 trial was done in three hospitals in southern China. Read More

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Solid Variant of Alveolar Rhabdomyosarcoma of Nasal Cavity.

Kathmandu Univ Med J (KUMJ) 2020 Jan.-Mar;18(69):102-104

Department of Otorhinolaryngology-Head and Neck Surgery, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Rhabdomyosarcoma comprises about half of the soft tissue tumors. Approximately 40% of the alveolar subtype occur in the head and neck region. Patients present with unilateral nasal mass with/without lymphadenopathy and with/without orbital manifestations. Read More

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February 2021

Nasal septal angiofibroma: less vascular behaviour than observed in radiological imaging, a rare case in a 51-year-old woman.

S Law C Burgess

Ann R Coll Surg Engl 2021 Feb;103(2):e48-e49

Department of Otorhinolaryngology, Musgrove Park Hospital, Taunton, UK.

Angiofibroma of the head and neck is classically found in the nasopharynx of an adolescent male. We present a rare case where an angiofibroma was diagnosed in the anterior nasal septum of a 51-year-old woman, the eighth nasal septal angiofibroma reported in a female. This case highlights how an angiofibroma in an older woman has a less vascular behaviour than one in an adolescent male, even though radiological enhancement may suggest that the lesion is highly vascularised. Read More

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February 2021

Implementation, adherence, and results of systematic SARS-CoV-2 testing for asymptomatic patients treated at a tertiary care regional radiation oncology network.

Radiat Oncol 2021 Feb 4;16(1):28. Epub 2021 Feb 4.

Levine Cancer Institute, Atrium Health, 1021 Morehead Medical Drive, Suite 1000, Charlotte, NC, 28204, USA.

Background: Coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus is a current pandemic. We initiated a program of systematic SARS-CoV-2 polymerase chain reaction (PCR) testing in all asymptomatic patients receiving radiotherapy (RT) at a large radiation oncology network in the Charlotte, NC metropolitan region and report adherence and results of the testing program.

Methods: Patients undergoing simulation for RT between May 18, 2020 and July 10, 2020 within the Levine Cancer Institute radiation oncology network who were asymptomatic for COVID-19 associated symptoms, without previous positive SARS-CoV-2 testing, and without recent high-risk contacts were included. Read More

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February 2021

Temporal bone primary inverted papilloma - Case Report and review of the literature.

Laryngorhinootologie 2021 02 1;100(2):99-103. Epub 2021 Feb 1.

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Medizinische Hochschule Hannover, Germany.

Inverted papilloma of middle ear is an extremely rare lesion of the respiratory epithelium that normally occurs in the nasal cavity and paranasal sinuses. So far less than 17 cases were described in literature. A 45-year-old patient was admitted in our Department with hearing loss, otorrhea and pulsing tinnitus on the right ear. Read More

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February 2021

Recurrent inverted papilloma coexisted with skull base lymphoma: A case report.

World J Clin Cases 2021 Jan;9(2):516-520

Section of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.

Background: Inverted papilloma is an uncommon neoplasm in the nasal cavity. It is a histologically benign tumor, but has a high recurrence and local invasion rate. In addition, nasal or skull base lymphoma is another rare neoplasm. Read More

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January 2021

Glomangiopericytoma of the inferior nasal turbinate: A case report.

Int J Surg Case Rep 2021 Feb 27;79:409-412. Epub 2021 Jan 27.

Faculty of Medecine of Casablanca, Morocco.

Introduction: Glomangiopericytoma is defined as a sinonasal tumor with perivascular myoid phenotype, which was first described in 1942 by Stout and Murray as a soft tissue tumor with characteristic proliferation including branching vessels and small vessel perivascular hyalinization. The tumor accounts for less than 0.5 % of all sinonasal neoplasms. Read More

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February 2021

Nasal-type extranodal NK/T-cell lymphoma: a diagnostic challenge.

BMJ Case Rep 2021 01 29;14(1). Epub 2021 Jan 29.

Otorhinolaryngology and Head and Neck Surgery Department, Centro Hospitalar de Vila Nova de Gaia, Porto, Portugal.

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January 2021