6,085 results match your criteria Malignant Tumors of the Nasal Cavity


A rare case of invasive sinonasal carcinosarcoma.

Int J Surg Case Rep 2020 May 7;70:243-248. Epub 2020 May 7.

School of Dentistry, Federal University of Pará (UFPA), Belém, PA, Brazil. Electronic address:

Introduction: Carcinosarcomas are rare malignant neoplasms formed by embryonic tissues (ectoderm and mesoderm) and present remarkably aggressive character with unfavourable prognosis. These lesions are rarely diagnosed in the sinonasal cavity and only a few cases are reported in the literature. This manuscript aimed to report a rare case of a large and aggressive sinonasal carcinosarcoma that involved the facial middle third and to discuss the proposed treatment. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231817PMC

Nasal congestion and nasal obstruction: An unusual presentation of renal cell carcinoma.

Radiol Case Rep 2020 Jul 7;15(7):970-974. Epub 2020 May 7.

Department of Pathology, Anatomy, and Laboratory Medicine, West Virginia University, Morgantown, WV, USA.

Renal cell cancer (RCC) is among the 10 most common cancers affecting both genders in the United States. Advanced RCC often remains clinically silent for much of its natural history. This can make the diagnosis challenging, especially when presenting symptoms arise from a metastasis. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214768PMC

Epithelial-Myoepithelial Carcinoma of the Lacrimal Sac and Literature Review of the Lacrimal System.

Allergy Rhinol (Providence) 2020 Jan-Dec;11:2152656720920600. Epub 2020 Apr 20.

Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Background: Epithelial-myoepithelial carcinomas make up less than 0.1% of head and neck malignancies and are regarded as rare, low-grade malignant neoplasms of the salivary gland. They are thought to arise from intercalated ducts with histopathology showing a classic biphasic morphology of an outer layer of myoepithelial cells and inner layer of epithelial cells. Read More

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http://dx.doi.org/10.1177/2152656720920600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175067PMC

Opium Use and Head and Neck Cancers: A Matched Case-Control Study in Iran.

Asian Pac J Cancer Prev 2020 03 1;21(3):783-790. Epub 2020 Mar 1.

Department of Otorhinolaryngology Head and Neck Surgery, Shafa Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Background: Head and Neck (H and N) cancers include malignant tumors of the nasal cavity, pharynx, paranasal sinuses, oral cavity, larynx and salivary glands. Opium use might be related to these cancers. The aim of this study was to investigate the relation between Opium and its Derivatives (O and D) use and the incidence of H and N cancers. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.3.783DOI Listing
March 2020
1.500 Impact Factor

Not All ENT Granulomas Are Wegener's - Keep Tuberculosis in Mind.

Eur J Case Rep Intern Med 2020 19;7(3):001469. Epub 2020 Feb 19.

Clinical Immunology Unit, Hospital de Santo António, Centro Hospitalar Universitário do Porto, Porto, Portugal.

affects the middle ear in rare cases and is a challenging diagnosis. In this case, we present a 57-year-old patient diagnosed with anti-neutrophil cytoplasmic antibody (ANCA)-negative granulomatosis with polyangiitis (GPA) following a biopsy result of nasal granulomas, who was immediately started on immunosuppressive treatment. Years later, she developed progressive hypoacusis. Read More

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http://dx.doi.org/10.12890/2020_001469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083184PMC
February 2020

Encapsulated Sinonasal Schwannoma Mimicking an Antrochoanal Polyp.

Niger Med J 2019 Nov-Dec;60(6):326-329. Epub 2020 Feb 24.

Department of Otorhinolaryngology, AKTH/Bayero University, Kano, Nigeria.

Extracranial schwannomas are uncommon neoplasms of the sinonasal tract arising from peripheral nerve shealth. Mostly acapsulated on histology, but few cases of encapsulated schwannomas have been reported. Its symptoms are nonspecific and initial clinical diagnosis is frequently missed. Read More

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http://dx.doi.org/10.4103/nmj.NMJ_104_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053271PMC
February 2020

The use of optical scanner for the fabrication of maxillary obturator prostheses.

Oral Maxillofac Surg 2020 Jun 9;24(2):157-161. Epub 2020 Mar 9.

Division of Maxillofacial Surgery, University Hospital "Maggiore della Carita", University of Eastern Piedmont, Novara, Italy.

Introduction: Maxillectomy following tumors or, more rarely, traumatic injuries may result in maxillary defects that may determine physical dysfunctions and functional impairment of speech and swallowing. The aim of our study was to present our experience in the management of post-maxillectomy patients by the use of obturator prostheses that were obtained by 3D digital casts via an intraoral scanner.

Methods: Patients with maxillary defects following maxillary and/or palatal resection or maxillary traumatic avulsion were selected for this clinical study between 2015 and 2018. Read More

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http://dx.doi.org/10.1007/s10006-020-00836-9DOI Listing

[Analysis of the effect of endoscopic surgery combined with conventional surgery in Neuroblastoma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Feb;34(2):128-130

Department of Otolaryngology Head and Neck Surgery,First Affiliated Hospital of Chinese Academy of Medical Sciences,Hefei,230001,China.

The aim of this study is to evaluate the efficacy of endoscopic surgery and conventional surgery combined with radiotherapy in the treatment of Neuroblastoma. Forty-three patients with olfactory neuroblastoma undergoing surgery combined with radiotherapy were retrospectively analyzed. The patients were divided into endoscopic surgery and conventional surgery. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2020.02.007DOI Listing
February 2020

[Comparison of radiological and clinicopathological features of craniofacial fibro-osseous lesions].

Zhonghua Bing Li Xue Za Zhi 2020 Feb;49(2):122-128

Department of Maxillofacial Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China.

To investigate the clinicopathological and radiological features of benign fibro-osseous lesion (BFOL). Sixty-five cases of craniofacial BFOL, eight cases of peripheral ossifying fibroma (POF) and one case of low-grade central osteosarcoma diagnosed at Sichuan Provincial People's Hospital between January 2010 and March 2019 were collected. The clinicopathologic features, hematoxylin-eosin and immunohistochemical (IHC) staining and radiographic features were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2020.02.004DOI Listing
February 2020

Nasal Cavity Metastasis From Colorectal Cancer Represents End-Stage Disease and Should Be Palliated.

Ann Coloproctol 2020 Apr 13;36(2):119-121. Epub 2019 Nov 13.

Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore.

Nasal metastases from colorectal cancer is rare. The presentation of nasal metastases is often very similar to primary nasal sinus adenocarcinoma. A high index of suspicion is required, especially in patients who have had a previous history of colorectal carcinoma. Read More

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http://dx.doi.org/10.3393/ac.2019.03.04DOI Listing

Tumours in European Shorthair cats: a retrospective study of 680 cases.

J Feline Med Surg 2020 Feb 12:1098612X20905035. Epub 2020 Feb 12.

Department of Comparative Biomedicine and Food Science, University of Padua, Padua, Italy.

Objectives: Naturally occurring tumours in domestic cats are less common than in dogs and represent the leading cause of death among older animals. The main objective of this study was to analyse a large data set of histologically diagnosed tumours to highlight the most common World Health Organization (WHO) tumour histotypes, the effect of age and sex, and the International Classification of Diseases for Oncology (ICD-O) topographical site predilections of feline breed-specific tumours.

Methods: A total of 680 feline tumours diagnosed in European Shorthair cats by three veterinary diagnostic laboratories located in central Italy from 2013 to 2019 were collected. Read More

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http://dx.doi.org/10.1177/1098612X20905035DOI Listing
February 2020

Ameloblastoma on the Maxillary Sinus: Cause of Unilateral Nasal Obstruction.

Cureus 2020 Jan 4;12(1):e6563. Epub 2020 Jan 4.

Surgery, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.

Ameloblastoma is a rare, benign (99%) or malignant (1%) tumour, which has derived from dental mesenchyme. We present a case of a patient mainly complaining about obstruction on the right nasal cavity. Endoscopy and computed tomography revealed a soft tissue mass occupying the maxillary sinus to the middle meatus causing complete obstruction of the right nasal cavity. Read More

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http://dx.doi.org/10.7759/cureus.6563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999722PMC
January 2020

Peripheral dentinogenic ghost cell tumor of the ethmoid sinus: A case report.

Medicine (Baltimore) 2020 Jan;99(3):e18896

Department of Otolaryngology-Head and Neck Surgery.

Rationale: The dentinogenic ghost cell tumor (DGCT), a locally invasive benign neoplasm, is one of the rarest odontogenic tumors, usually developing in the maxilla or mandible. It can be classified into 2 types: intraosseous (central) and extraosseous (peripheral). Here, we describe the first case of a peripheral DGCT located in the ethmoid sinus. Read More

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http://dx.doi.org/10.1097/MD.0000000000018896DOI Listing
January 2020

Epithelial-myoepithelial carcinoma originating from a minor salivary gland in the nasal septum: A case report and literature review.

Medicine (Baltimore) 2020 Jan;99(5):e19072

Department of Otorhinolaryngology, Yonsei University Wonju College of Medicine.

Rationale: Epithelial-myoepithelial carcinoma is an extremely rare, malignant neoplasm that occurs most frequently in the major salivary glands and accounts for approximately 1% of all salivary gland neoplasms. Few reports have described the presence of epithelial-myoepithelial carcinoma in the sinonasal region; hence, the treatment guideline and prognosis remain unclear.

Patient Concerns: We reported a case of a 75-year-old woman with complaint of nasal obstruction and frequent epistaxis for 3 years. Read More

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http://dx.doi.org/10.1097/MD.0000000000019072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004653PMC
January 2020

[Clinical analysis of sinonasal chondrosarcoma in 47 cases].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Jan;55(1):14-20

Department of Otorhinolaryngology, Eye, Ear, Nose and Throat Hospital, Shanghai Medwal College, Fudan University, Shanghai 200031, China.

To discuss the treatment, pathological subtypes and recurrence of sinonasal chondrosarcoma, and to identify the prognostic factors. Between January 1994 and May 2018, 47 patients with sinonasal chondrosarcoma who were treated in Eye, Ear, Nose and Throat Hospital, Shanghai Medwal College, Fudan University were retrospectively reviewed, including 19 males and 28 females, aging from 7 months to 71 years old, with a median age of 38 years old. The clinical symptoms, location of tumor, surgical method, pathological subtype, recurrence and prognosis were collected and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2020.01.004DOI Listing
January 2020

Diagnostic challenges in malignant tumors of nasal cavity and paranasal sinuses.

J Oral Maxillofac Pathol 2019 Sep-Dec;23(3):378-382

Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, India.

Introduction: Malignant tumors of sinonasal tract are extremely rare and comprise 3% of all head and neck malignant tumors. They constitute 0.2% of all invasive carcinomas. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_300_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948046PMC
January 2020

The Specific Magnetic Resonance Imaging Indicators in Predicting Clear-Cell Renal Cell Carcinoma Metastatic to the Sinonasal Region.

J Comput Assist Tomogr 2020 Jan/Feb;44(1):70-74

From the Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Purpose: The aim of this study was to determine the valuable magnetic resonance imaging (MRI) features of sinonasal metastatic clear-cell renal cell carcinoma (cc-RCC), especially focusing on its dynamic-enhanced characteristics.

Methods: The conventional and dynamic-enhanced MRI findings of 8 patients with histopathologically confirmed sinonasal metastatic cc-RCC were reviewed by 2 radiologists. The control group of 8 patients with capillary hemangioma underwent the same MRI protocol. Read More

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http://dx.doi.org/10.1097/RCT.0000000000000948DOI Listing
January 2020

. Respiratory epithelial adenomatoid hamartoma - typical but underdiagnosed pathology of nasal cavity and sinuses.

Cas Lek Cesk 2019 ;158(6):253-255

Respiratory epithelial adenomatoid hamartoma (REAH) is relatively new diagnosis, firstly described in WHO tumour classification in 2005. It is a benign lesion affecting nose and paranasal sinuses. Although REAH was considered a rare entity, it is recently more frequently revealed in histopathological exam in patients undergoing endoscopic surgery for nasal polyposis. Read More

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January 2020

[Pathological diagnosis and progress in small round cell tumors of the sinonasal and nasal cavity].

Zhonghua Bing Li Xue Za Zhi 2020 01;49(1):97-102

Department of Pathology, Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2020.01.023DOI Listing
January 2020

[Spectrum analysis of pathological classification in 463 cases with nasal and paranasal sinuses malignant tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Dec;33(12):1176-1180

Department of Otorhinolaryngology Head and Neck Surgery,Hospital 301,PLA General Hospital,Beijing,100853,China.

The characteristics of pathological histological classification of nasal and paranasal sinuses malignant tumors in the past 10 years were analyzed, so as to provide possible basis, direction and ideas for the development of relevant effective treatment measures for nasal and paranasal sinuses malignant tumors in clinical practice. The clinical data of patients with nasal and paranasal sinuses malignant tumors admitted to PLA general hospital from January 2009 to December 2018 were collected. Pathological types were retrospectively analyzed, and disease spectrum distribution, composition ratio and variation tendency of these patients were calculated. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.12.015DOI Listing
December 2019

Recurrence of nasal type NK/T cell lymphoma presenting as neurolymphomatosis on 18F-FDG PET/CT: A case report and literature review.

Medicine (Baltimore) 2020 Jan;99(1):e18640

Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital.

Introduction: NK/T cell lymphomas seldom involve the peripheral nervous system. We report a case of recurrent nasal type NK/T cell lymphoma presenting as neurolymphomatosis and its manifestation on F-FDG PET/CT.

Patient Concerns: A 55-year old man presented with a mass in the right nasal cavity was diagnosed with extranodal NK/T cell lymphoma, nasal type. Read More

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http://dx.doi.org/10.1097/MD.0000000000018640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946263PMC
January 2020

Acute Management of Massive Epistaxis After Nasotracheal Extubation.

Anesth Prog 2019 ;66(4):211-217

Department of Dental Anesthesiology and Pain Management, Tohoku University Hospital, Sendai, Japan.

Epistaxis is one of the most common complications of nasotracheal intubation and can be life-threatening. However, there is little discussion in the current literature on the acute management of massive epistaxis after nasotracheal extubation. This is a report of 2 patients who experienced severe unanticipated nasal bleeding immediately after extubation, 1 after a surgical procedure for oral cancer and another after restorative dental treatment. Read More

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http://dx.doi.org/10.2344/anpr-66-02-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938169PMC

Sinonasal Oncocytic Papilloma-A Series of 20 Cases With Special Emphasis on Recurrences.

Laryngoscope Investig Otolaryngol 2019 Dec 30;4(6):567-572. Epub 2019 Sep 30.

Department of Otorhinolaryngology-Head and Neck Surgery University of Helsinki and HUS Helsinki University Hospital Helsinki Finland.

Objective: Reports on sinonasal oncocytic papilloma (SNOP) are scarce. The aim of this retrospective study was to evaluate the clinical features of this rarest form of sinonasal papilloma with special emphasis on the pattern of recurrences and on the potential factors predicting them.

Study Design: Retrospective study. Read More

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http://dx.doi.org/10.1002/lio2.308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929580PMC
December 2019

An Adult Case of Nasal Chondromesenchymal Hamartoma: Imaging Characteristics Including Diffusion-Weighted Images.

Acta Med Okayama 2019 Dec;73(6):529-532

Department of Otorhinolaryngology, Kagawa Prefectural Central Hospital, Takamatsu 760-8557, Japan.

Nasal chondromesenchymal hamartoma (NCMH), a rare, benign, nasal cavity tumor, typically occurs in children. Differential diagnosis is difficult because NCMH often presents with non-specific findings, including cystic components and invasion of the surrounding area on T2-weighted magnetic resonance images. Here, we present a rare adult case of NCMH, with no clear hyperintensity on diffusion-weighted images (DWI), and bone remodeling on the tumor margins on computed tomography. Read More

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http://dx.doi.org/10.18926/AMO/57718DOI Listing
December 2019

Virtual Surgical Planning in Subscapular System Free Flap Reconstruction of Midface Defects.

Oral Oncol 2020 02 19;101:104508. Epub 2019 Dec 19.

Thomas Jefferson University, Department of Otolaryngology - Head & Neck Surgery, Philadelphia, PA, USA.

Objectives: Reconstruction of the midface has many inherent challenges, including orbital support, skull base reconstruction, optimizing midface projection, separation of the nasal cavity and dental rehabilitation. Subscapular system free flaps (SF) have sufficient bone stock to support complex reconstruction and the option of separate soft tissue components. This study analyzes the effect of virtual surgical planning (VSP) in SF for midface on subsite reconstruction, bone segment contact and anatomic position. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2019.104508DOI Listing
February 2020

[Renal clear cell carcinoma metastatic to the nasal cavity: report of a case].

Zhonghua Bing Li Xue Za Zhi 2019 12;48(12):976-978

Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Province (Guangdong Academy of Medical Sciences), Guangzhou 510080, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.12.014DOI Listing
December 2019

Impact of pretherapeutic neutrophil-to-lymphocyte ratio, serum albumin, body-mass index, and advanced lung cancer inflammation index on clinical outcome in sinonasal squamous cell carcinoma.

J Craniomaxillofac Surg 2020 Jan 27;48(1):33-37. Epub 2019 Nov 27.

Department of Otorhinolaryngology and Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.

Background: Squamous cell carcinoma of the nasal cavity and paranasal sinuses is a rare and aggressive cancer entity with poor survival rates. Data on this group of head and neck tumors are scarce. Inflammation and cachexia-based markers and their impact on clinical outcome have been studied in several cancer groups. Read More

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http://dx.doi.org/10.1016/j.jcms.2019.11.010DOI Listing
January 2020

DMBT1 has a protective effect on allergic rhinitis.

Biomed Pharmacother 2020 Jan 25;121:109675. Epub 2019 Nov 25.

Department of Otorhinolaryngology-Head and Neck Surgery, Second Affiliated Hospital of Second Military Medical University, Shanghai, 200003, China. Electronic address:

Objective: Deleted in malignant brain tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich (SRCR) protein, predominantly expressed in nasal mucosal epithelial cells. In previous experiments, we found large amounts of DMBT1 present in the nasal cavity mucosa of allergic rhinitis (AR) patients. However, the exact role of DMBT1 in AR remains unclear. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.109675DOI Listing
January 2020

Malignant peripheral nerve sheath tumor of nasal cavity and paranasal sinus with 13 years of follow-up-A case report and review of literature.

Clin Case Rep 2019 Nov 4;7(11):2194-2201. Epub 2019 Oct 4.

Department of Radiation Oncology University of Mississippi Medical Center Jackson Mississippi.

Although extremely rare, sarcomas including malignant peripheral nerve sheath tumors should be considered in the differential diagnosis of sino-nasal tract lesions. Long-term cure is possible through definitive operative management followed by adjuvant therapy. Read More

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http://dx.doi.org/10.1002/ccr3.2465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878039PMC
November 2019

A Comparative Study Between Traditional Microscopic Surgeries and Endoscopic Endonasal Surgery for Skull Base Chordomas.

World Neurosurg 2020 Feb 27;134:e1099-e1107. Epub 2019 Nov 27.

Department of Neurosurgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. Electronic address:

Background: Skull base chordomas (SBCs) are rare clinically aggressive neoplasms, developing local recurrences after surgical resection. Although SBCs have traditionally been resected by craniotomy or microscopic transsphenoidal surgery (TSS), the recent development of the endoscopic endonasal approach (EEA) has revolutionized treatment strategies through minimally invasive techniques. This study aimed to evaluate clinical outcomes after traditional microsurgeries or EEAs for SBCs. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.113DOI Listing
February 2020

[Nasal cavity and paranasal sinus rhabdomyosarcoma:a clinicopathological and immunohistochemistry characteristics study of fifteen cases].

Zhonghua Bing Li Xue Za Zhi 2019 11;48(11):884-886

Department of Pathology, China-Japan Friendship Hospital, Beijing 100029, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.11.010DOI Listing
November 2019

Sinonasal melanoma: a systematic review of the prognostic factors.

Int J Oral Maxillofac Surg 2020 May 22;49(5):549-557. Epub 2019 Nov 22.

João de Barros Barreto University Hospital (HUJBB), Federal University of Pará (UFPA), Belém, Pará, Brazil; Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.

The objective was to evaluate the available published data on sinonasal melanoma and analyse its clinical features, treatment modalities, and prognostic factors. An electronic search was undertaken in March 2018 in multiple databases. Eligibility criteria included publications with sufficient clinical, histological, and immunohistochemical information to confirm the diagnosis. Read More

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http://dx.doi.org/10.1016/j.ijom.2019.11.001DOI Listing

Outcomes following proton therapy for Ewing sarcoma of the cranium and skull base.

Pediatr Blood Cancer 2020 02 17;67(2):e28080. Epub 2019 Nov 17.

Department of Radiation Oncology, College of Medicine, University of Florida, Jacksonville, Florida.

Purpose: Despite the dosimetric advantages of proton therapy, little data exist on patients who receive proton therapy for Ewing sarcoma of the cranium and skull base. This study reports local disease control and toxicity in such patients.

Materials/methods: We reviewed 25 patients (≤21 years old) with nonmetastatic Ewing sarcoma of the cranium and skull base treated between 2008 and 2018. Read More

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http://dx.doi.org/10.1002/pbc.28080DOI Listing
February 2020

Remote Leptomeningeal Dissemination in Olfactory Neuroblastoma Mimicking Multiple Parasagittal Meningiomas: Diagnostic and Therapeutic Challenge.

World Neurosurg 2020 Feb 14;134:361-364. Epub 2019 Nov 14.

Department of Neurological Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio, USA; Department of Head and Neck Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio, USA. Electronic address:

Background: Olfactory neuroblastoma (ON) is a highly aggressive and locally recurrent neoplasm. Distant systemic metastases are not uncommon, but remote leptomeningeal dissemination is extremely rare.

Case Description: We report 2 cases of ON previously treated with endoscopic endonasal radical surgical resection and radiotherapy. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.042DOI Listing
February 2020

Clinical Experience of Endoscopic Endonasal Approach in the Innovative, Newly Developed Operating Room "Smart Cyber Operating Theater (SCOT)".

World Neurosurg 2020 Feb 9;134:293-296. Epub 2019 Nov 9.

Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.

Background: When medical devices and equipment in an operating room are connected to a network, vast amounts of data concerning the progress of the operation and the patient's condition can be comprehensively processed to improve the precision and safety of the surgical procedure. To make this possible, a next-generation networked operating room, "Smart Cyber Operating Theater" (SCOT), has been developed with medical-engineer cooperation. SCOT integrates stand-alone medical devices using the "OPeLiNK" communication interface. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.021DOI Listing
February 2020

Isolated Nasal Metastasis From Renal Cell Carcinoma 9 Years After Nephrectomy Seen on FDG PET.

Clin Nucl Med 2020 Feb;45(2):e110-e111

From the PET/CT Center, Department of Nuclear Medicine.

A 56-year-old man presented with intermittent epistaxis. Nasopharyngoscope revealed a hemorrhagic mass occupying the left nasal cavity. The patient had a history of renal clear cell carcinoma. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002836DOI Listing
February 2020

A unique uterine cervical "teratocarcinosarcoma": a case report.

Diagn Pathol 2019 Nov 4;14(1):122. Epub 2019 Nov 4.

Department of Pathology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-City, Saitama, 350-1298, Japan.

Background: Teratocarcinosarcoma (TCS) is a rare aggressive tumor of the nasal cavity and paranasal sinuses and has both epithelial and two or more mesenchymal components. In other organs, 5 cases of ovarian tumors closely resembling TCS have been reported; however, there has been no published case of cervical TCS. Herein, we describe a unique case of cervical tumor that had carcinosarcomatous and teratomatous features, resembling a sinonasal TCS. Read More

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http://dx.doi.org/10.1186/s13000-019-0890-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827231PMC
November 2019

Extended Endonasal Endoscopic Complete Resection of a Solitary Intraorbital Myofibroma: A Case Report and Literature Review.

World Neurosurg 2020 Apr 1;136:283-288. Epub 2019 Nov 1.

Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

Background: Infantile myofibromatosis is a rare benign disease of mesenchymal origin. It occurs mostly in infants but can occur in children and adults. It presents in 2 forms: solitary and multicentric. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.10.149DOI Listing
April 2020
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Prospective characterization of postoperative nasal deformities in patients undergoing endoscopic endonasal skull-base surgery.

Int Forum Allergy Rhinol 2020 02 30;10(2):256-264. Epub 2019 Oct 30.

Department of Otolaryngology, Eye & Ear Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Background: Surgeons have become increasingly aware of the impact of endoscopic endonasal surgery (EES) of the skull base on sinonasal-related quality of life. Prior retrospective investigation described a correlation between nasoseptal flap (NSF) reconstruction in EES with postoperative nasal deformities, such as nasal dorsum collapse. The primary objective of this study was to prospectively evaluate the incidence of, and contributing factors to, postoperative changes in nasal structure following EES. Read More

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http://dx.doi.org/10.1002/alr.22466DOI Listing
February 2020

Primary intraosseous carcinoma of the maxilla arising from an odontogenic keratocyst: a case report and review of the literature.

Gen Dent 2019 Nov-Dec;67(6):26-32

A 47-year-old man was referred for treatment of a painful lesion of 5 months' duration located on the left side of the maxilla. A small perforation in the buccal cortex was observed during the intraoral examination. Cone beam computed tomography (CBCT) showed an extensive, well-delimited radiolucent lesion extending from the alveolar ridge to the nasal cavity. Read More

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December 2019
7 Reads

Deregulation of Selected MicroRNAs in Sinonasal Squamous Cell Carcinoma: Searching for Potential Prognostic Biomarkers.

Folia Biol (Praha) 2019 ;65(3):142-151

Institute of Clinical Biochemistry and Diagnostics, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic.

Sinonasal carcinomas are head and neck tumours arising from the nasal cavity and paranasal sinuses characterized by unfavourable outcome, difficult treatment, diagnosis and prognosis. MicroRNAs are key molecules in the regulation of development and progression of cancer and their expression profiles could be used as prognostic biomarkers, to predict the patients' survival and response to treatment. In this study, we used quantitative real‑time PCR with TaqMan® Advanced miRNA Assays to investigate the relative expression values of selected micro- RNAs in a unique set of formalin-fixed paraffin-embedded tissue samples obtained from 46 patients with sinonasal squamous cell carcinoma. Read More

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March 2020
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Outcome of Endoscopic Endonasal Surgery in Pediatric Craniopharyngiomas.

World Neurosurg 2020 Feb 17;134:e277-e288. Epub 2019 Oct 17.

Division of Pediatric Neurosurgery, Department of Neurosurgery, Bellaria Hospital, Bologna, Italy.

Background: In the last years, few reports have shown the feasibility of the endoscopic endonasal approach (EEA) for craniopharyngiomas in pediatric patients. For these tumors, recent studies have suggested less aggressive surgery, favoring the preservation of the patient's quality of life.

Objective: The aim of this study was to assess the outcome of the EEA in a large series with specific attention on the long-term functional sequelae. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.10.039DOI Listing
February 2020

Association between coarse particulate matter (PM) and nasopharyngeal carcinoma among Taiwanese men.

J Investig Med 2020 Feb 16;68(2):419-424. Epub 2019 Oct 16.

Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan

The nasopharyngeal tract traps mainly coarse particles in inhaled air. Soluble carcinogenic compounds, endotoxins, and trace metals contained in these particles are potential causes of inflammation and oxidative stress which could enhance carcinogenesis. The aim of this study was to determine the association between coarse particulate matter (PM) and nasopharyngeal cancer (NPC). Read More

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http://dx.doi.org/10.1136/jim-2019-001119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063388PMC
February 2020
1 Read

A Rarely Seen Mass of Nasal Cavity: Seromucinous Hamartoma.

J Craniofac Surg 2020 Jan/Feb;31(1):e65-e67

Department of Otorhinolaryngology & Head and Neck Surgery, Istanbul Medical Faculty, University of Istanbul, Istanbul, Turkey.

Seromucinous hamartoma (SH) is a rarely seen benign polypoid mass of the sinonasal tract. Although the most common presentation symptom is nasal obstruction, most of the patients are asymptomatic. In this paper, the authors present an additional case of SH and discuss its differential diagnosis. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005899DOI Listing

Sphenopalatine Ganglion Blocks in the Management of Head and Neck Cancer-Related Pain: A Case Series.

A A Pract 2019 Dec;13(12):450-453

From the Division of Pain Medicine, Department of Anesthesiology, University of Virginia, Charlottesville, Virginia.

Head and neck cancer can be painful, debilitating, and refractory to oral medications. Due to the association of the sphenopalatine ganglion (SPG) with maxillary nerve sensory fibers, SPG blocks may be used to treat the pain of the hard and soft palate, tonsils, nasal cavity, paranasal sinuses, oral gingiva, premaxillary soft tissue, maxilla, and orbital floor. We present the first case series of performing SPG blocks utilizing TX360 nasal atomizers or angiocatheters to treat head and neck cancer-related pain. Read More

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http://dx.doi.org/10.1213/XAA.0000000000001106DOI Listing
December 2019

Radiologic, genetic, and endocrine findings in isolated congenital nasal pyriform aperture stenosis patients.

Int J Pediatr Otorhinolaryngol 2020 Jan 5;128:109705. Epub 2019 Oct 5.

College of Medicine, The Ohio State University, 370 W 9th Ave, Columbus, OH, USA, 43210.

Background: Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of upper airway obstruction in neonates. It can occur either associated with a solitary median maxillary central incisor (SMMCI) in 40-75% of cases or as an isolated morphogenic variant. Brain MRI is routinely performed in patients with CNPAS with a SCMMI due to the concomitant risks of intracranial midline defects of the hypothalamic-pituitary axis (HPA), holoprosencephaly, or associated endocrine dysfunction. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.109705DOI Listing
January 2020
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Simultaneous Resection of Pituitary Macroadenoma and Sphenoid Sinus Inverted Papilloma: The Challenge of Operating Sinonasal and Skull Base Pathologies Through a Single-Stage Endoscopic Endonasal Approach.

World Neurosurg 2020 Jan 9;133:260-265. Epub 2019 Oct 9.

Division of Neurosurgery, Department of Surgery, Sanatorio Julio Mendez, Buenos Aires, Argentina.

Background: Coexistence of sinonasal and skull base tumors is uncommon but possible, and the endonasal route seems to be the best option to manage both lesions simultaneously. We report the first case in the English literature of concomitant sphenoid sinus inverted papilloma and pituitary macroadenoma treated through an endoscopic endonasal approach.

Case Description: A 68-year-old man presented with a history of progressive visual loss and nasal obstruction. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.09.159DOI Listing
January 2020
4 Reads

[Potential of computer-assisted navigation systems in the surgical treatment of chronic sinusitis, nasal cavity and paranasal sinuses tumors].

Vestn Otorinolaringol 2019 ;84(4):6-12

First Pavlov State Medical University, Saint Petersburg, Russia, 197022.

Purpose: To describe the principles of medical navigation systems in head and neck surgery, the possibility of their application and the existing limitations.

Material And Methods: The article presents the generalized experience of image-guidance equipment using in the ENT Department of First Pavlov State Medical University. 298 operations, mostly FESS, were performed from 2013 to 2018 under the control of navigation system. Read More

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http://dx.doi.org/10.17116/otorino2019840416DOI Listing
November 2019
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Temporal Galeofascial Flap for Reconstruction After Transmaxillary Approaches to the Clival Region.

World Neurosurg 2020 Feb 14;134:e68-e74. Epub 2019 Sep 14.

Department of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy.

Background: A paramount concern after transmaxillary approaches has been skull base reconstruction. Regional pedicled flaps represent the best reconstructive option. We have described a technique to harvest a lateral-based multilayered vascularized flap for skull base reconstruction after resection of large tumors using the transmaxillary transpterygoid approach (TMTPA). Read More

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http://dx.doi.org/10.1016/j.wneu.2019.09.038DOI Listing
February 2020
4 Reads

Defining Clinical Indications of Proton Beam Therapy at National Level in the Kingdom of Saudi Arabia.

Saudi Med J 2019 Sep;40(9):879-886

King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail.

The Saudi Particle Therapy Centre (SPTC) is establishing proton beam therapy (PBT) services within Kingdom of Saudi Arabia (KSA). Thus, national guidelines for the pertinent draft, and recommendations of PBT for cancer patients are utmost important. Saudi Particle Therapy Centre invited a panel of expert radiation oncologists practicing within KSA to formulate national clinical practice guidelines for the referral, absolute and relative indications and dose/fractionation for PBT. Read More

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http://dx.doi.org/10.15537/smj.2019.9.24496DOI Listing
September 2019
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