5,831 results match your criteria Malignant Tumors of the Nasal Cavity


Causes of mortality in cases with extra nodal natural killer/T-cell lymphoma, nasal type: A cohort study.

PLoS One 2019 17;14(4):e0214860. Epub 2019 Apr 17.

Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.

Objective: Extra nodal natural killer/T-cell lymphoma (ENKTL), nasal type is a rare and highly aggressive type of non-Hodgkin's lymphoma (NHL) commonly presented in the nasal cavity or lymphatic system. However, the common causes of mortality in ENKTL remain unclear. We conducted a retrospective population-based cohort study to elucidate the different causes of mortality in ENKTL and illustrate the main causal and associated risk factors leading to death. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214860PLOS

Sinonasal (Schneiderian) papilloma of the lacrimal sac.

Proc (Bayl Univ Med Cent) 2019 Jan 16;32(1):121-123. Epub 2019 Jan 16.

Department of Otolaryngology, Baylor Scott & White-Temple/Texas A&M UniversityTempleTexas.

Sinonasal papillomas, also known as Schneiderian papillomas, are benign but infiltrative epithelial neoplasms that arise from ectodermally derived pseudostratified ciliated (or Schneiderian) epithelium that lines the sinonasal tract and nasal cavity. We describe a rare case of a sinonasal papilloma confined to the lacrimal duct and sac in a 45-year-old man who presented with 10 months of right-sided epiphora and swelling of his medial right lower eyelid. He was found to have a 10 × 10 mm area of distension near the right lacrimal sac and underwent an external dacryocystorhinostomy. Read More

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http://dx.doi.org/10.1080/08998280.2018.1533357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442893PMC
January 2019

Wood dust and urinary 15-F isoprostane in Italian industry workers.

Environ Res 2019 Mar 27;173:300-305. Epub 2019 Mar 27.

Cancer Factor Risk Branch, Regional Cancer Prevention Laboratory, ISPRO-Study, Prevention and Oncology Network Institute, 50139, Florence, Italy. Electronic address:

Wood dust is one of the most common occupational exposures, with about 3.6 million of workers in the wood industry in Europe. Wood particles can deposit in the nose and the respiratory tract and cause adverse health effects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00139351193019
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http://dx.doi.org/10.1016/j.envres.2019.03.058DOI Listing
March 2019
5 Reads

Angiocentric Centrofacial Lymphoma as a Challenging Diagnosis in an Elderly Man.

Am J Case Rep 2019 Mar 30;20:412-418. Epub 2019 Mar 30.

School of Medicine and Health Sciences, Tecnologico de Monterrey, Guadalajara, Jalisco, Mexico.

BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical presentation includes fever, weight loss, nasal obstruction, epistaxis, nasal or facial edema, as well as necrotic ulcers in the nasal cavity, gums, and palate. It has been found to have an important association with the Epstein-Barr virus. Read More

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https://www.amjcaserep.com/abstract/index/idArt/913856
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http://dx.doi.org/10.12659/AJCR.913856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454582PMC
March 2019
2 Reads

Primary adrenal extranasal NK/T cell lymphoma with subcutaneous involvement demonstrated on FDG PET/CT: A clinical case report.

Medicine (Baltimore) 2019 Mar;98(11):e14818

Department of Nuclear Medicine.

Rationale: Primary adrenal non-Hodgkin lymphomas are predominant diffuse large B cell lymphoma with frequently bilateral adrenal involvement, but the occurrence of nasal type extranodal NK/T cell lymphoma is relatively rare.

Patient Concerns: A 40-year-old woman complaining of left back pain for 2-month was admitted to our department.

Diagnosis: Based on the feature of enhanced computed tomography (CT) images which showed huge bilateral well-defined adrenal masses with heterogeneous enhancement, she was tentatively diagnosed as having primary adrenal malignancy. Read More

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http://Insights.ovid.com/crossref?an=00005792-201903150-0004
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http://dx.doi.org/10.1097/MD.0000000000014818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426610PMC
March 2019
5 Reads
5.723 Impact Factor

[Diagnostic challenge of biphenotypic sinonasal sarcoma].

Ann Pathol 2019 Feb 26. Epub 2019 Feb 26.

Centre de biologie sud, centre hospitalier sud, institut de pathologie multisite, hospices civils de Lyon, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France; Université Claude-Bernard Lyon I, 43, boulevard du 11-Novembre-1918, 69100 Villeurbanne cedex, France.

Sinonasal biphenotypic sarcoma has recently been described and included in the 2017 WHO classification. It is a low-grade sarcoma which is characterized by PAX3 rearrangements. It remains a diagnostic challenge because of its scarcity, and its considerable histologic overlap with other cellular spindle cell neoplasms. Read More

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http://dx.doi.org/10.1016/j.annpat.2019.01.005DOI Listing
February 2019
1 Read

Blastic plasmacytoid dendritic cell neoplasm with unusual extracutaneous manifestation: Two case reports and literature review.

Medicine (Baltimore) 2019 Feb;98(6):e14344

Department of Pathology, Konkuk University School of Medicine, Seoul, Korea.

Rationale: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy. This disease almost always presents with cutaneous involvement.

Patient Concerns: The 1st patient was a 16-year-old girl who presented with recurrent epistaxis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380774PMC
February 2019
2 Reads

Letter to the Editor Regarding "Combined Minimally Invasive Supraciliary and Transfacial Approach for Large Tumors with Skull Base and Sinonasal Involvement".

World Neurosurg 2019 02;122:707

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Ansari Nagar East, New Delhi, India.

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http://dx.doi.org/10.1016/j.wneu.2018.09.043DOI Listing
February 2019
1 Read

Computed tomographic features of adenoid cystic carcinoma in the palate.

Cancer Imaging 2019 Jan 31;19(1). Epub 2019 Jan 31.

Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth Peoples Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China.

Background: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.

Methods: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed. Read More

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https://cancerimagingjournal.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s40644-019-0190-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357373PMC
January 2019
13 Reads

Clinicopathological study of malignant melanoma in a regional cancer center.

Indian J Cancer 2018 Jul-Sep;55(3):292-296

Department of Pathology, A.H. Regional Cancer Centre, Cuttack, Odisha, India.

Background: : Malignant melanoma is a tumor of melanocytic origin. Although uncommon in India as compared with the west, its prevalence is increasing.

Objectives: To document the pattern of clinicopathological features of malignant melanoma cases attending in a regional cancer center in eastern India. Read More

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http://dx.doi.org/10.4103/ijc.IJC_612_17DOI Listing
January 2019
7 Reads

Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14223

Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.

Rationale: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms with only a few reported cases affecting the nasal cavity, paranasal sinuses, and anterior skull base.

Patient Concerns: A 12-year-old girl with a mass in her nose was admitted to the Department of Otorhinolaryngology of Shenzhen Children's Hospital. She had a 4-month history of progressive, unilateral right nasal obstruction, unilateral mucopurulent rhinorrhea, foul nasal odor, snoring, hyposmia, occasional epistaxis, and no headache, no facial numbness, without eye swelling and vision loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358413PMC
January 2019
9 Reads
5.723 Impact Factor

[Clinical differences between primary nasopharyngeal NK/T-cell lymphoma and primary nasal cavity NK/T-cell lymphoma with nasopharynx extension].

Zhonghua Zhong Liu Za Zhi 2019 Jan;41(1):56-62

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To investigate the clinical and prognostic differences between primary nasopharyngeal natural killer (NK)/T-cell lymphoma (NP NKTCL) and extranodal NK/T-cell lymphoma of the nasal cavity with nasopharynx extension (N-NP NKTCL). A total of 89 patients with NP NKTCL and 113 patients with N-NP NKTCL from January 2000 to June 2015 were retrospectively analyzed. Clinical and pathological features, treatment responses and prognosis were compared between the two groups. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2019.01.010DOI Listing
January 2019
1 Read

Surgery alone versus post-operative radiotherapy for sinonasal malignant melanoma: a meta-analysis.

Authors:
R Hu B-B Yang

J Laryngol Otol 2018 Dec;132(12):1051-1060

Department of Otolaryngology,Second Affiliated Hospital,School of Medicine,Zhejiang University,Zhejiang,China.

Objective: Sinonasal malignant melanoma is a relatively rare malignancy with poor prognosis, and effective treatments remain elusive. This analysis aimed to explore whether post-operative radiotherapy conferred any survival advantages in patients with this disease when compared with surgery alone.

Methods: Published studies were identified by searching four electronic databases. Read More

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http://dx.doi.org/10.1017/S0022215118002189DOI Listing
December 2018
14 Reads

Transnasal endoscopic surgery in selected nasal-ethmoidal cancer with suspected brain invasion: Indications, technique, and outcomes.

Head Neck 2019 Jan 12. Epub 2019 Jan 12.

Unit of Otorhinolaryngology - Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.

Background: In nasal-ethmoidal malignancies, brain involvement is associated with dismal prognosis.

Method: Patients undergoing endoscopic resection with transnasal craniectomy and subpial dissection (ERTC-SD) for brain-invading nasal-ethmoidal cancer between 2008 and 2016 were included. Complications were analyzed in all patients, whereas oncological outcomes only in patients with pathological brain invasion. Read More

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http://doi.wiley.com/10.1002/hed.25621
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http://dx.doi.org/10.1002/hed.25621DOI Listing
January 2019
12 Reads

Paraganglioma Presenting as a Nasal Septal Mass: Case Report and Literature Review.

Case Rep Otolaryngol 2018 6;2018:1413960. Epub 2018 Dec 6.

Associate Professor of Clinical Otolaryngology Head and Neck Surgery, Keck School of Medicine, Los Angeles, CA, USA.

Objectives: To describe a rare case of a paraganglioma arising from the nasal septum and review the diagnosis and management of paragangliomas in the nasal cavity and paranasal sinuses.

Methods: We present a case of a 70-year-old female presenting with persistent nasal congestion and obstruction. Nasal endoscopy revealed a posterior septal mass approaching the sphenoid sinuses and partially obstructing the nasopharynx. Read More

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https://www.hindawi.com/journals/criot/2018/1413960/
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http://dx.doi.org/10.1155/2018/1413960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304863PMC
December 2018
18 Reads

Sinonasal hemangiopericytoma caused hypophosphatemic osteomalacia: A case report.

Medicine (Baltimore) 2018 Dec;97(52):e13849

Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu.

Rationale: Tumor-induced osteomalacia (TIO) is a rare, paraneoplastic syndrome featured with fibroblast growth factor 23 (FGF23) secretion primarily by benign mesenchymal tumors and sometimes by malignancies. TIO diagnosis and treatment is often delayed because TIO usually has nonspecific generalized bone pain and weakness, and location of TIO tumor is quite challenging. Very few TIO caused by sinonasal hemangiopericytoma have been reported in the literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000013849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314754PMC
December 2018
2 Reads
5.723 Impact Factor

Squamous cell carcinoma of the head and neck in children.

Int J Pediatr Otorhinolaryngol 2019 Feb 20;117:131-137. Epub 2018 Nov 20.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, United States. Electronic address:

Objective: To discuss the presentation, evaluation, and management of squamous cell carcinoma of the head and neck in the pediatric population.

Methods: Medical records of pediatric (≤20 years) patients treated for squamous cell carcinoma of the head and neck between 1996 and 2016 were reviewed. Data pertaining to clinical presentation, diagnostic methods, treatment plan, complications, recurrence, follow-up, or outcome were collected. Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.11.019DOI Listing
February 2019
1 Read

Characteristics and management of sinonasal paragangliomas: a systematic review.

Int Forum Allergy Rhinol 2019 Apr 20;9(4):413-426. Epub 2018 Dec 20.

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ.

Background: Paragangliomas of the nasal cavity and paranasal sinuses, although exceedingly rare, can exhibit frequent and aggressive recurrences. Our objective was to evaluate tumor characteristics, clinical course, management, and associated complications of sinonasal paragangliomas METHODS: A systematic review of the literature was performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, searching for sinonasal paraganglioma. Studies meeting inclusion criteria were assessed for level of evidence. Read More

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http://doi.wiley.com/10.1002/alr.22261
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http://dx.doi.org/10.1002/alr.22261DOI Listing
April 2019
17 Reads
2.371 Impact Factor

Immature Teratoma of Nasal Septum: A Case Report.

Iran J Otorhinolaryngol 2018 Nov;30(101):355-359

Department of Otorhinolaryngology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.

Introduction: Teratomas are neoplastic tumors derived from totipotent germ cells containing a wide assortment of tissues originating from all three germ cell layers. Teratomas can be mature or immature depending on the presence of immature tissues; typically neuroepithelial tissue. Immature teratomas can be oncologically benign or malignant, and can be divided into three grades with increasingly aggressive biological behavior. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291815PMC
November 2018
1 Read

[Metastases of cervical cancer to the nasal cavity and paranasal sinus with maxillofacial symptoms: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1832-1833

A 41 year old female complained of left eyelid, cheek and face erythema, swelling with pain for 7 days. She was diagnosed with cervical squamous cell carcinoma, stage ⅢA a year ago. The anterior rhinoscopy examination showed that the dry scab adheres to the left nasal cavity, and a small amount of reddish mass were found, and the touch was brittle. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.016DOI Listing
December 2018
1 Read

Comparisons of skin toxicity in patients with extranodal nasal-type natural killer/T-cell lymphoma after treatment with intensity-modulated radiotherapy and conventional radiotherapy.

J Cancer Res Ther 2018 Dec;14(Supplement):S975-S979

Department of Radiation Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, P.R. China.

Background: Intensity-modulated radiation therapy (IMRT) has been more widely used in extranodal nasal-type natural killer/T-cell lymphoma (NKTCL) because it can maximally improve the local control rate of tumor and reduce the radiation dose received by surrounding normal tissues. However, there has been no consensus on whether IMRT can help to lower the toxic and adverse reactions caused by radiation therapy. The aim of this study is to compare skin toxicity caused by IMRT and conventional radiotherapy in Stage I-II NKTCL. Read More

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http://dx.doi.org/10.4103/0973-1482.192791DOI Listing
December 2018
2 Reads

Unilateral endoscopic resection with transnasal craniectomy for sinonasal intestinal-type adenocarcinoma: A bi-institutional case-control study on 54 patients.

Oral Oncol 2018 Dec 26;87:89-96. Epub 2018 Oct 26.

Unit of Otorhinolaryngology - Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.

Objectives: Intestinal-type adenocarcinoma (ITAC) of the ethmoid mostly affects patients exposed to wood dust and has been traditionally treated with bilateral resection. The aim of the present study was to validate unilateral endoscopic resection with transnasal craniectomy (uERTC) in selected ITACs.

Materials And Methods: Patients affected by ITAC receiving uERTC from 2004 to 2017 at two tertiary referral centers were retrospectively analyzed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13688375183039
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http://dx.doi.org/10.1016/j.oraloncology.2018.10.027DOI Listing
December 2018
3 Reads

Patterns of failures after surgical resection in olfactory neuroblastoma.

J Neurooncol 2019 Jan 30;141(2):459-466. Epub 2018 Nov 30.

Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Introduction: Patterns of failure in patients with olfactory neuroblastoma (ONB) according to two surgical approaches, craniofacial resection (CFR) and endoscopic surgery (ENDO), have yet to be analyzed.

Methods: We retrospectively reviewed 28 patients with surgically treated ONB between January 1995 and October 2017. Fourteen (50. Read More

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http://link.springer.com/10.1007/s11060-018-03056-0
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http://dx.doi.org/10.1007/s11060-018-03056-0DOI Listing
January 2019
12 Reads

Data Set for the Reporting of Carcinomas of the Nasal Cavity and Paranasal Sinuses: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Arch Pathol Lab Med 2019 Apr 30;143(4):424-431. Epub 2018 Nov 30.

From the Department of Translational Research, University of Pisa, Pisa, Italy (Dr Franchi); the Department of Pathology, University of Texas Southwestern Medical Center, Dallas (Dr Bishop); the Institute of Clinical Pathology and Medical Research, Westmead Hospital, Sydney, Australia (Dr Coleman); the Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands (Dr Flucke); the Head and Neck Medical Oncology Department, Fondazione International Collaboration on Cancer Reporting Istituto Nazionale dei Tumori, and University of Milan, Milan, Italy (Dr Licitra); the Department of Otolaryngology, Instituto Universitario de Oncología del Principado de Asturias, Centro de Investigación Biomédica en Red de Cancer, Hospital Universitario Central de Asturias, Oviedo, Spain (Dr Llorente Pendás); the Department of Pathology, University of Virginia, Charlottesville (Dr Stelow); St James and Dublin Dental Hospitals and Trinity College, Sir Patrick Dunne Research Laboratory, and St James Hospital, Dublin, Ireland (Dr Toner); the Department of Pathology, University Health Network, Toronto, Ontario, Canada (Dr Weinreb); the Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, Florida (Dr Wenig); and the Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills (Dr Thompson).

The International Collaboration on Cancer Reporting was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic multi-institutional intercountry data collection to guide cancer care in the future. This data set has been developed by the collaborative efforts of an international multidisciplinary panel of experts involved in the care of patients with carcinomas of the nasal cavity and paranasal sinuses (sinonasal tract). The nasal cavity and paranasal sinuses (including frontal, sphenoid, ethmoid, and maxillary sinuses) comprise a very complex anatomic area of the head and neck, affected by a sometimes bewildering array of neoplasms. Read More

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http://dx.doi.org/10.5858/arpa.2018-0404-SADOI Listing

Comparing Kadish, TNM, and the modified Dulguerov staging systems for esthesioneuroblastoma.

J Surg Oncol 2019 Jan 22;119(1):130-142. Epub 2018 Nov 22.

Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: Esthesioneuroblastoma (ENB) is a rare neuroendocrine tumor. The purpose of this study was to compare the Kadish, tumor-node-metastasis (TNM), and Dulguerov's modified TNM staging in order to determine the impact of the stage on primary surgical treatment selection, margin status, and survival.

Methods: The National Cancer Database (NCDB) was used to identify patients diagnosed with ENB between 2004 to 2015. Read More

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http://dx.doi.org/10.1002/jso.25293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352736PMC
January 2019
19 Reads

Giant sellar metastasis from renal cell carcinoma: A case report and literature review.

Medicine (Baltimore) 2018 Nov;97(47):e13376

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Rationale: Sellar metastasis is a rare and complex disease whose clinical features are strongly associated with the primary malignancy. Here, we present a rare case of giant sellar metastasis spread from renal cell carcinoma (RCC).

Patient Concerns: A 30-year-old Chinese woman was admitted to our Hospital, reporting headache, nasal congestion, nausea, vomiting, and a sharp decline in her right eye vision. Read More

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http://dx.doi.org/10.1097/MD.0000000000013376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392949PMC
November 2018
19 Reads

Large cell neuroendocrine carcinoma of the nasal cavity: an extremely rare and new distinct entity.

Pan Afr Med J 2018 29;30:188. Epub 2018 Jun 29.

ENT Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

Large cell neuroendocrine carcinoma (LCNEC) is a rare but distinct entity of nasal cavity carcinomas. Only a very few cases have been reported in the nasal cavity. Its treatment is not well established. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.188.14992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235514PMC
December 2018
19 Reads

NUT carcinoma of the nasal cavity that responded to a chemotherapy regimen for Ewing's sarcoma family of tumors: a case report.

BMC Cancer 2018 Nov 19;18(1):1134. Epub 2018 Nov 19.

Department of Hematology/Oncology, Japan Community Healthcare Organization Kyushu Hospital, Fukuoka, Japan.

Background: Nuclear protein in testis (NUT) carcinoma (NC) is a rare epithelial malignancy characterized by rearrangement of the NUT gene on chromosome 15. If NC is not suspected, it is often diagnosed as other malignancies. We present the case of NC of the nasal cavity that responded to a chemotherapy regimen for Ewing's sarcoma family of tumors (ESFT). Read More

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http://dx.doi.org/10.1186/s12885-018-5087-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245604PMC
November 2018
19 Reads

[The application of the hidrogel-based medicinal compositions for the targeted delivery of medications in rhino- and otosurgery].

Vestn Otorinolaringol 2018;83(5):68-70

Research and Clinical Centre of Otorhinolaryngology, Russian Medico-Biological Agency, Moscow, Russia.

The objective of the present study was the analysis of the application of the hydrogel-based medicinal compositions for the treatment of the patients presenting with pathological changes in the nasal cavity and paranasal sinuses during the postoperative period. A total of 25 patients at the age from 18 to 60 years with the diseases of the nasal cavity and paranasal sinuses were available for the examination including 12 ones with polypous polysinusitis and 13 patients having benign neoplasms in the nasal cavity, paranasal sinuses, and the base of the skull. All these patients underwent endoscopic endonasal polysinusotomy. Read More

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http://dx.doi.org/10.17116/otorino20188305168DOI Listing
January 2018
26 Reads

Inflammatory Myofibroblastic Tumors in Paranasal Sinus and Nasopharynx: A Clinical Retrospective Study of 13 Cases.

Biomed Res Int 2018 15;2018:7928241. Epub 2018 Oct 15.

Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China.

Background: Inflammatory myofibroblastic tumor (IMT), as a mesenchymal tumor, is common in the lung and abdomen but rare in the paranasal sinus and nasopharynx.

Objective: This study aimed to summarize the clinical characteristics of IMT in the paranasal sinus and nasopharynx and analyze the relationship between the treatment and the overall survival (OS).

Method: The clinical features, treatment, and follow-up data of patients diagnosed with IMT of the paranasal sinus or nasopharynx from 2006 to 2017 were retrospectively analyzed, and the previous literature was reviewed. Read More

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https://www.hindawi.com/journals/bmri/2018/7928241/
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http://dx.doi.org/10.1155/2018/7928241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205320PMC
February 2019
19 Reads

Seromucinous hamartoma of inferior turbinate: A case report.

Medicine (Baltimore) 2018 Nov;97(45):e13022

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Hwasun, South Korea.

Rationale: Seromucinous hamartoma is a rare benign glandular proliferation of the sinonasal tract and nasopharynx, and the majority of lesions occur on the posterior nasal septum.

Patient Concerns: The patient had complaints of rhinorrhea, sneezing, and itching for a number of years, and recurrent right nasal bleeding for which the patient underwent endoscopic removal of a right inferior turbinate tumor. The biopsy result was low-grade, non-intestinal type adenocarcinoma, and the patient was referred to our hospital. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811090-0001
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http://dx.doi.org/10.1097/MD.0000000000013022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250520PMC
November 2018
23 Reads

Choanal Atresia and Other Neonatal Nasal Anomalies.

Clin Perinatol 2018 12 18;45(4):751-767. Epub 2018 Sep 18.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Room 6161B, Baltimore, MD 21287, USA.

Congenital nasal deformities can cause nasal obstruction with early respiratory distress. Choanal atresia is characterized by no communication between the nasal cavity and nasopharynx. Pyriform aperture stenosis involves more anterior nasal obstruction with limited intranasal space. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00955108183139
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http://dx.doi.org/10.1016/j.clp.2018.07.011DOI Listing
December 2018
27 Reads

[Improvement and effect analysis of a new neuroendoscopic trans-nasal-sphenoidal pituitary tumor resection approach].

Zhonghua Yi Xue Za Zhi 2018 Oct;98(37):3021-3024

Department of Neurosurgery, Center of Prolactinoma, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

To modify the individual neuroendoscopic surgical approach of pituitary tumors with specific imaging features, and to analyze the clinical outcomes. The clinical data of 116 patients with pituitary tumors who underwent surgical treatment at the pituitary tumor diagnosis and treatment center of Ruijin Hospital from April 2014 to December 2017 were collected, then the resection effects and complication rates of pituitary tumors from three different kinds of transsphenoidal approaches (e.g. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.37.015DOI Listing
October 2018
2 Reads

Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature.

World Neurosurg 2019 Feb 1;122:196-202. Epub 2018 Nov 1.

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: A persistent craniopharyngeal canal (PCC) is a rare cause of cerebrospinal fluid rhinorrhea in children. The condition often coexists with other midline facial defects, such as cleft palate. Children with PCC may also have pituitary dysfunction or neoplasms, such as craniopharyngiomas within the canal. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183243
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http://dx.doi.org/10.1016/j.wneu.2018.10.138DOI Listing
February 2019
17 Reads

Compressive optic neuropathy secondary to Ewing sarcoma in the paranasal sinus: A case report.

Medicine (Baltimore) 2018 Nov;97(44):e13027

Department of Ophthalmology.

Rationale: Ewing sarcoma localized in the paranasal sinuses, compressing the optic nerve, is very rare, with no prior case reports PATIENT CONCERNS:: A 68-year-old woman presented with decreased visual acuity in her left eye and paresthesia of the left face. Brain magnetic resonance imaging showed heterogeneously enhancing mass in the left paranasal sinuses with adjacent bone destruction, extending to the extraocular muscles and optic nerve of the left orbit. A biopsy of the nasal cavity confirmed Ewing sarcoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000013027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221559PMC
November 2018
6 Reads

Morphoproteomics and Biomedical Analytics Identify the c-Myc, EZH2, Sirt1 and CXCR4 Pathways as Potential Blocks to Differentiation Leading to Proliferation and Metastatic Potential in Sinonasal Undifferentiated Carcinoma (SNUC) and Provide Therapeutic Options: A Case Study.

Ann Clin Lab Sci 2018 Sep;48(5):659-664

Biomedical Analytics, Houston, TX, USA.

Sinonasal undifferentiated carcinoma (SNUC) is a highly malignant tumor in the nasal cavity or paranasal sinuses. Morphoproteomics has defined its biology to some degree, allowing the identification of targeted therapeutic options with clinical efficacy [1]. This study's objective was to identify putative SNUC pathways that are known to pose a block in differentiation both in early embryogenesis and in tumorigenesis or that might promote metastasis and recurrent disease. Read More

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September 2018
44 Reads

Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia.

Tohoku J Exp Med 2018 10;246(2):141-146

Department of Otolaryngology-Head and Neck Surgery, Tohoku University School of Medicine.

Myeloid sarcoma (MS) is an uncommon extramedullary malignant tumor, and often represents a subgroup of acute myeloid leukemia (AML). MS of paranasal sinus origin is extremely rare. We report an uncommon case of sinonasal MS associated with AML, who was successfully treated with hematopoietic stem-cell transplantation. Read More

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https://www.jstage.jst.go.jp/article/tjem/246/2/246_141/_art
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http://dx.doi.org/10.1620/tjem.246.141DOI Listing
October 2018
20 Reads

Dacryoendoscopy-assisted nasal endoscopic marsupialization for congenital dacryocystocele.

Int J Pediatr Otorhinolaryngol 2018 Dec 19;115:54-57. Epub 2018 Sep 19.

Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital, Aichi, Japan.

Objective: To examine the surgical outcome of dacryoendoscopy-assisted nasal endoscopic marsupialization for congenital dacryocystocele.

Methods: This is a retrospective, observational study that included 7 sides of 6 patients with congenital dacryocystocele. The surgical indication in 5 of the patients was acute dacryocystitis while one of the patients had no spontaneous resolution after long-term observation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876183047
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http://dx.doi.org/10.1016/j.ijporl.2018.09.017DOI Listing
December 2018
10 Reads

Endoscopic management of Esthesioneuroblastoma: Our experience and review of the literature.

J Clin Neurosci 2018 Dec 16;58:117-123. Epub 2018 Oct 16.

Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.

During the last two decades evolution of the endoscopic endonasal approaches (EEA) has offered the option of minimally invasive techniques in the management of esthesioneuroblastomas (ENB), either as endoscope assisted cranial resection or as pure endoscopic procedures. This study presents the use of pure EEA in the management of ENB in our center, along with a literature review. We retrospectively reviewed the clinical, radiology and pathology records of patients with ENB treated during the period July 2006 to January 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183000
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http://dx.doi.org/10.1016/j.jocn.2018.09.011DOI Listing
December 2018
5 Reads
1.318 Impact Factor

Semi-quantitative analysis of pre-treatment morphological and intratumoral characteristics using F-fluorodeoxyglucose positron-emission tomography as predictors of treatment outcome in nasal and paranasal squamous cell carcinoma.

Quant Imaging Med Surg 2018 Sep;8(8):788-795

Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Background: To investigate the utility of quantitative morphological and intratumoral characteristics obtained by F-fluorodeoxyglucose positron-emission tomography/computed tomography (FDG-PET/CT) for the prediction of treatment outcome in patients with nasal or paranasal cavity squamous cell carcinoma (SCC).

Methods: Twenty-four patients with nasal or paranasal cavity SCC who received curative non-surgical therapy (a combination of super-selective arterial cisplatin infusion and radiotherapy) were retrospectively analyzed. From pre-treatment FDG-PET data, a total of 13 parameters of quantitative morphological characteristics (tumor volume, surface area and sphericity), intratumoral characteristics (the maximum and mean standard uptake value, three intratumoral histogram and four textural parameters) and total lesion glycolysis (TLG) were respectively calculated. Read More

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http://qims.amegroups.com/article/view/21328/21135
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http://dx.doi.org/10.21037/qims.2018.09.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177367PMC
September 2018
2 Reads

Reviewing indications for panendoscopy in the investigation of head and neck squamous cell carcinoma.

J Laryngol Otol 2018 Oct 5;132(10):901-905. Epub 2018 Oct 5.

Department of Otolaryngology,Head and Neck Surgery,Royal Adelaide Hospital and University of Adelaide,Australia.

Background: The role of panendoscopy in the modern investigation of head and neck cancer is changing with the development of improved radiological techniques, in-office biopsy capabilities and the low rate of synchronous primary tumours. This study aimed to review the indications for panendoscopy in the investigation of newly diagnosed head and neck cancer.

Method: A retrospective review was conducted of 186 patients with newly diagnosed head and neck cancer, between January 2014 and December 2015, at two tertiary centres. Read More

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https://www.cambridge.org/core/product/identifier/S002221511
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http://dx.doi.org/10.1017/S0022215118001718DOI Listing
October 2018
11 Reads
0.700 Impact Factor

Renal cell carcinoma metastatic to the sinonasal cavity: A review and report of 8 cases.

Ear Nose Throat J 2018 Sep;97(9):E6-E12

Department of Otorhinolaryngology-Head and Neck Surgery, Bordeaux University Hospital, Place Amélie Raba-Leon, 33000 Bordeaux, France.

Renal cell carcinoma (RCC) metastatic in the sinonasal cavity is rare. In many cases, it represents the initial presentation of RCC. We conducted a retrospective chart review to report the clinical presentation, imaging, and treatment of RCC metastases in the sinonasal cavity at two tertiary care referral centers. Read More

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http://dx.doi.org/10.1177/014556131809700902DOI Listing
September 2018
6 Reads

Low-Grade Papillary Schneiderian Carcinoma of the Sinonasal Cavity and Temporal Bone.

Ann Otol Rhinol Laryngol 2018 Dec 29;127(12):974-977. Epub 2018 Sep 29.

1 Division of Head and Neck Surgery & Communication Sciences, Department of Surgery, Duke University Medical Center, Durham, NC, USA.

Objectives:: The aim of this study was to further characterize a newly described neoplasm, low-grade papillary Schneiderian carcinoma, occurring simultaneously in the sinonasal cavity and mastoid. Additionally, the authors review the only 2 similar cases within the literature and describe the common clinical features, radiographic findings, and pathologic characteristics of this exceptionally rare disease process.

Methods:: Chart review for single patient, review of literature. Read More

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http://journals.sagepub.com/doi/10.1177/0003489418803391
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http://dx.doi.org/10.1177/0003489418803391DOI Listing
December 2018
11 Reads

Endocrine and Metabolic Outcomes After Transcranial and Endoscopic Endonasal Approaches for Primary Resection of Craniopharyngiomas.

World Neurosurg 2019 Jan 26;121:e8-e14. Epub 2018 Sep 26.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

Objective: Craniopharyngiomas have traditionally been resected through the transcranial approaches (TCA). The endoscopic endonasal approach (EEA) has recently been developed as an alternative for surgeons, but controversy remains regarding which approach has better outcomes. We compared the endocrine and metabolic outcomes of TCA and EEA in patients who underwent primary resection of craniopharyngiomas. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.092DOI Listing
January 2019
5 Reads

Increased risk of incident nasopharyngeal carcinoma with exposure to air pollution.

PLoS One 2018 28;13(9):e0204568. Epub 2018 Sep 28.

Department of Medical Research, Tungs' Taichung Metroharbor Hospital, Taichung, Taiwan.

Background: Nasopharyngeal carcinoma (NPC) is a race-specific malignancy. The nasal cavity is the main entry point for air pollutants or poisonous gases into the human body. However, the risk of NPC in populations exposed to air pollution remains unknown. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161893PMC
March 2019
3 Reads

Successful Use of Extracorporeal Membrane Oxygenation for Respiratory Failure After Cranial Surgery.

World Neurosurg 2018 Dec 24;120:426-429. Epub 2018 Sep 24.

Department of Neurology & Neurosurgery, University of Miami Health System, Miami, Florida, USA. Electronic address:

Background: The use of extracorporeal membrane oxygenation (ECMO) for cardiopulmonary support is indicated for refractory respiratory failure but carries a high morbidity and mortality in the neurosurgical setting due to associated risks of intracranial hemorrhage.

Case Description: We describe the case of a 62-year-old man who underwent craniotomy for resection of an esthesioneuroblastoma involving the anterior skull base and extending intracranially, through the cribriform plate into the right epidural space. He developed refractory hypoxemic and hypercapnic respiratory failure and circulatory shock in the immediate postoperative period. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.087DOI Listing
December 2018
17 Reads

Sinonasal paraganglioma and Cushing's syndrome: A rare association.

J Cancer Res Ther 2018 Sep;14(Supplement):S812-S814

Department of Radiology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

In general, paragangliomas are symptomatic tumors, which may be clinically taken for other tumors, benign or malignant lesions. Paragangliomas of the nasal cavity and paranasal sinuses are an extremely rare entity and what is even rarer is its association with ectopic adrenocorticotropic hormone production. We report this very rare case to highlight the rare association of Cushing's syndrome with nasal paraganglioma and the importance of total surgical resection in its treatment. Read More

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http://dx.doi.org/10.4103/0973-1482.187354DOI Listing
September 2018
29 Reads

Clinical value of Tc-HYNIC-TOC SPECT/CT for the diagnosis primary small cell neuroendocrine carcinomas of the nasal cavity and paranasal sinuses.

Clin Imaging 2018 Nov - Dec;52:365-369. Epub 2018 Sep 20.

Department of Otolaryngology Head and Neck Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), NO. 321 Zhongshan Road, Nanjing 210008, Jiangsu, China; Research Institution of Otolaryngology, NO. 321 Zhongshan Road, Nanjing 210008, Jiangsu, China. Electronic address:

Purpose: To evaluate the diagnostic value of Tc-HYNIC-TOC SPECT/CT in the detection of primary small cell neuroendocrine carcinomas of the nasal cavity and paranasal sinuses.

Methods: From September 2005 to November 2015, 19 patients (mean age 53.9 years, range 37-77; male 6, female 13) with sinonasal small cell neuroendocrine carcinoma (SNEC) underwent whole-body Tc-HYNIC-TOC SPECT/CT scan. Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.09.010DOI Listing
January 2019
1 Read

High-grade myoepithelial carcinoma can show histologically undifferentiated/anaplastic features.

Ann Diagn Pathol 2018 Dec 11;37:20-24. Epub 2018 Sep 11.

Department of Pathology, National University Health System, Singapore. Electronic address:

High grade malignant tumors with a poorly-/un-differentiated morphology pose significant diagnostic challenges. Increasingly, the use of adjunct immunohistochemical and molecular tests to characterize and delineate the histopathologic phenotype of these tumors has become necessary, particularly in head and neck tumors. Recently, several entities with a poorly-/un-differentiated light microscopic morphology have been defined based on specific immunohistochemical and genetic characteristics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10929134183023
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http://dx.doi.org/10.1016/j.anndiagpath.2018.09.004DOI Listing
December 2018
2 Reads

Intranasal Osteosarcoma in a Dog-A Case Report.

Top Companion Anim Med 2018 Jun 23;33(2):35-39. Epub 2018 Apr 23.

Department of Clinic and Veterinary Surgery, School of Agrarian and Veterinary Sciences, São Paulo State University (UNESP/FCAV), Jaboticabal, SP, Brazil.

Osteosarcoma is the most commonly reported bone tumor in dogs, typically affecting the axial and appendicular skeleton. Involvement of the paranasal sinuses and the nasal cavity is extremely rare. This report describes a 6-year-old, female, cross-breed dog presented with signs of 90 days duration and diagnosed with a mass located in the right nasal cavity. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.04.001DOI Listing
June 2018
2 Reads