3,390 results match your criteria Malignant Testicular Tumor Imaging


When to ask for an MRI of the scrotum.

Andrology 2021 May 8. Epub 2021 May 8.

Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy.

Background: Multiparametric MRI (mpMRI) of the scrotum has been established as a useful second-line diagnostic tool for the investigation of scrotal diseases. Recently, recommendations on clinical indications for scrotal MRI were issued by the Scrotal and Penile Imaging Working Group of the European Society of Urogenital Radiology.

Objective: To update current research on when to ask for an MRI of the scrotum. Read More

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Uncommon Testicular Germ Cell Tumor Thrombus in Azygos Vein Detected by FDG PET/CT.

Clin Nucl Med 2021 Jul;46(7):e347-e348

Nuclear Medicine, Bezmialem Vakıf University Faculty of Medicine, Istanbul, Turkey.

Abstract: A 40-year old man admitted to the nuclear medicine department to undergo PET/CT for restaging of known testicular germ cell tumor. The patient had a history of orchiectomy for left testis and left nephrectomy with retroperitoneal lymph node dissection. Histopathology revealed testicular germ cell tumor. Read More

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Retroperitoneal extension of massive ulcerated testicular seminoma through the inguinal canal: A case report.

Arch Ital Urol Androl 2021 Mar 19;93(1):64-67. Epub 2021 Mar 19.

Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University of Chieti, Urology Unit, SS. Annunziata Hospital, Chieti.

Introduction: Testicular cancers represent about 5% of all urological malignancies and 1-1.5% of all male neoplasms. Most of the testicular cancers are localized (68%) at diagnosis. Read More

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A case of abdominal migration of the testes presenting with azoospermia.

Nagoya J Med Sci 2021 Feb;83(1):195-199

Department of Obstetrics and Gynecology, Asada Ladies Clinic, Nagoya, Japan.

31-year-old male was referred to our hospital due to azoospermia. Physical examination revealed impalpable testes in the scrotum, and operative scar presented at lower abdominal midline. Magnetic resonance imaging (MRI) revealed that small testes were located subcutaneously in the lower abdominal midline. Read More

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February 2021

Testicular ultrasound underestimates the size of small testicular masses: a radiologic-pathologic correlation study.

World J Urol 2021 Mar 12. Epub 2021 Mar 12.

Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Park 213, Baltimore, MD, 21287, USA.

Purpose: Increasing use and resolution of testicular ultrasound imaging has resulted in a greater diagnosis of non-palpable small testicular masses and subsequent over-treatment with orchiectomy. Our aim was to determine the diagnostic accuracy of testicular ultrasound to accurately determine the pathologic size of small testicular masses (SMTMs) and to evaluate the association of various measurements with benign pathology.

Methods: Retrospectively, an institutional testicular cancer database was reviewed to evaluate the patients who underwent an orchiectomy for a testicular mass seen on ultrasound from 2003 to 2017. Read More

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[Diagnostic value of diffusion-weighted imaging and conventional magnetic resonance imaging in testicular tumor].

Zhonghua Yi Xue Za Zhi 2021 Mar;101(9):661-664

Department of Radiology, Affiliated Hospital of Jining Medical College, Jining 272029, China.

Apparent diffusion coefficient(ADC) of magnetic resonance imaging≤0.90×10 mm/s and T2-hypointensity, intratuminal septa, and peritumoral infiltration could achieve best diagnostic efficiency. ADC values and cyst or necrosis were independent predictors for the differential diagnosis of nonseminomatous germ cell tumor versus seminoma and nonseminomatous germ cell tumor versus lymphoma. Read More

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40-Year-Old Man With Left Leg Swelling and Abdominal Pain.

Mayo Clin Proc 2021 03;96(3):782-787

Advisor to residents and Consultant in Medical Oncology, Mayo Clinic, Rochester, MN. Electronic address:

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Testicular cancer with neurological symptoms indicates brain metastases.

Lancet 2021 02;397(10276):e7

Department of Urology, Los Angeles County + University of Southern California Medical Center, Los Angeles, CA, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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February 2021

177Lu-PSMA Therapy for Metastatic Testicular Mixed Germ Cell Tumor.

Clin Nucl Med 2021 May;46(5):415-418

From the Department of Nuclear Medicine, Istanbul Faculty of Medicine.

Abstract: Prostate-specific membrane antigen (PSMA) overexpression in various tumors are demonstrated in both in vitro and in vivo studies. Prostate-specific membrane antigen-directed radionuclide therapies are generally used in prostate cancer and could be also useful in PSMA-avid other malignancies. Herein, we present a case of a 46-year-old male patient who had progressive metastatic testicular mixed germ cell tumor, despite repeated operations and treatments. Read More

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Pure testicular choriocarcinoma Cannonball metastases as a presenting imaging feature: A case report and a review of literature.

Radiol Case Rep 2021 Apr 9;16(4):923-928. Epub 2021 Feb 9.

Healthpoint Medical Center, Amman, Jordan.

Pure testicular choriocarcinoma is an extremely rare subtype of nonseminomatous germ cell tumor, accounting for less than 1% of all germ cell tumors and only 0.19% of all testicular tumors. It is a highly aggressive malignant tumor with early multiorgan metastasis and poor prognosis. Read More

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Renal lobar dysmorphism: a potential mimic of renal malignancy.

BMJ Case Rep 2021 Feb 19;14(2). Epub 2021 Feb 19.

Urology, Mercy University Hospital, Cork, Ireland.

A renal pseudotumour is any apparent renal mass that simulates a tumour on radiological imaging but is composed of normal tissue. Renal pseudotumours may be inflammatory, vascular, postsurgical or congenital. We report a case of renal lobar dysmorphism (RLD) of the kidney, a congenital renal pseudotumour. Read More

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February 2021

Contents of the inguinal canal: identification by different imaging methods.

Radiol Bras 2021 Jan-Feb;54(1):56-61

Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil.

Although the correct diagnosis of inguinal hernias can often be made by clinical examination, there are several situations in which imaging methods represent the best option for evaluating such hernias, their content, and the possible complications. In addition, bulging of the inguinal region is not always indicative of a hernia, because other lesions, including tumors, cysts, and hematomas, also affect the region. The objective of this pictorial essay is to demonstrate what can be identified within inguinal hernias. Read More

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February 2021

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions.

Sci Rep 2021 Feb 10;11(1):3456. Epub 2021 Feb 10.

Department of Morphology Surgery and Experimental Medicine, University of Ferrara, Via L. Ariosto 34, 44121, Ferrara, Italy.

How to differentiate with MRI-based techniques testicular germ (TGCTs) and testicular non-germ cell tumors (TNGCTs) is still under debate and Radiomics may be the turning key. Our purpose is to investigate the performance of MRI-based Radiomics signatures for the preoperative prediction of testicular neoplasm histology. The aim is twofold: (i), differentiating TGCTs and TNGCTs status and (ii) differentiating seminomas (SGCTs) from non-seminomatous (NSGCTs). Read More

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February 2021

Paraneoplastic limbic encephalitis as initial presentation of testicular neoplasm: A case report.

Clin Imaging 2021 Aug 3;76:61-64. Epub 2021 Feb 3.

Weill Cornell Medicine, Department of Radiology, 525 East 68(th) Street, New York, NY 10065, United States of America.

Paraneoplastic limbic encephalitis (PLE) is an immunopathologic syndrome associated with malignancy and represents a rare remote outcome of tumor on the nervous system. We report a case of PLE caused by a regressed testicular germ cell tumor in an otherwise healthy young man, who presented with acute-onset confusion, memory impairment and anterograde amnesia. Prompt recognition of PLE is critical as it allows early treatment of both the primary tumor and PLE-related neurologic impairments, which can be severe and irreversible if treatment is delayed. Read More

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Late testicular relapse two decades after primary extragonadal germ cell tumor with uncommon metastases: a case report.

J Med Case Rep 2021 Feb 5;15(1):59. Epub 2021 Feb 5.

The Department of Urology, Japan Community Health care Organization Kani Tono Hospital, 1221-5 Dota, Kani-shi, Gifu, 509-0206, Japan.

Background: Extragonadal germ cell tumor (EGCT) is a relatively rare condition, reportedly representing 3-7% of all germ cell tumors. We report a patient who had metachronous testicular tumor with uncommon metastases 20 years after primary retroperitoneal EGCT treatment, along with a corresponding literature review.

Case Presentation: A 49-year-old Japanese man visited our department in November 2017 with chief complaints of indolent right scrotum enlargement and a right inguinal mass. Read More

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February 2021

Cervical malignant teratoma masquerading as a hematoma: a case report.

J Int Med Res 2021 Feb;49(2):300060520984597

Department of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.

Background: Post-pubertal teratomas, which mostly occur at 20 to 40 years old, are more likely to be found at a metastatic site in up to 20% of cases and may be inadvertently overlooked. We present a case of cervical malignant teratoma that masqueraded as a hematoma. A 24-year-old man presented to our institution with a 4-month history of a progressively relapsing painless mass in the neck, despite conservative treatments with oral medications. Read More

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February 2021

Semen quality and testicular adrenal rest tumour development in 46,XY congenital adrenal hyperplasia: the importance of optimal hormonal replacement.

Eur J Endocrinol 2021 Apr;184(4):487-501

Department of Pediatric Endocrinology and Diabetes, Children's Hospital, University of Münster, Münster, Nordrhein-Westfalen, Germany.

Objective: To study the impact of the quality of therapeutic control on fertility and on the prevalence of testicular adrenal rest tumours (TART) in young males with congenital adrenal hyperplasia (CAH).

Design: Combined cross-sectional and retrospective clinical study.

Methods: Twenty-nine patients and age-matched controls underwent clinical investigation, including semen analysis, testicular and adrenal ultrasound imaging, and serum and hair steroid analysis. Read More

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Primary intratesticular rhabdomyosarcoma in children: a case report and review of the literature.

J Med Case Rep 2021 Jan 31;15(1):37. Epub 2021 Jan 31.

Department of pathology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania.

Background: The importance of this paper is to help to emphasize the importance of chemotherapy for children with pure intratesticular rhabdomyosarcoma after radical inguinal orchiectomy is done as first treatment of rhabdomyosarcoma. The information provided in this paper about the follow-up outcomes of the patient described in this paper, it highlights that, recurrence and even metastasis of intratesticular rhabdomyosarcoma in children are more likely to occur if surgery it not combined with chemotherapy.

Case Presentation: Herein, we present a 6-year old African male child with a 3 months history of a painless right intratesticular tumour. Read More

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January 2021

Beyond germ cell tumors, unusual testicular and extra-testicular masses and mass-like lesions: MRI and US pictorial review.

Clin Imaging 2021 Jun 14;74:106-122. Epub 2021 Jan 14.

Department of Medical Imaging, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Testicular ultrasound (US) studies are nowadays widely performed as being readily available, cost effective with no side effects. Testicular ultrasounds are ordered to help in the diagnosis of various conditions, but more specifically, in cryptorchidism. Other reasons for conducting testicular ultrasonography include testicular pain to confirm presence of epididymitis or orchitis. Read More

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Unusual finding after treatment for testicular cancer.

BMJ Case Rep 2021 Jan 8;14(1). Epub 2021 Jan 8.

Urology, Sengkang General Hospital, Singapore.

In the context of a post-treatment testicular germ cell tumour, an abdominal lesion found on surveillance CT studies led to a differential diagnosis, including recurrent germ cell tumour. We report the case of a 48-year-old man who was noted to have a new interval soft tissue lesion on a surveillance CT scan, 5 years after initial orchidectomy and chemotherapy. Excision of this lesion and histopathological review revealed an intra-abdominal desmoid. Read More

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January 2021

Apparent diffusion coefficient values of cryptorchid testes and malignant transformation of cryptorchidism (MTC) (seminoma) in postpubertal patients.

Br J Radiol 2021 Mar 7;94(1119):20200624. Epub 2021 Jan 7.

Department of Radiology, The People's Hospital of Longhua, The Affiliated Hospital of Southern Medical University, Shenzhen 518109, China.

Objectives: Diffusion-weighted imaging signal contrast can be quantified by apparent diffusion coefficient (ADC) maps, which reflect the diffusion properties of the examined tissue and are helpful for identifying pathology. To determine ADC values of cryptorchid testes in post-pubertal patients and assess performance for characterizing cryptorchid testes.

Methods: The medical records from 35 patients with unilateral scrotal vacuity were retrospectively reviewed. Read More

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Clinical and seminal parameters associated with testicular microlithiasis and its severity in males from infertile couples.

Hum Reprod 2021 03;36(4):891-898

Andrology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.

Study Question: Is there an association of testicular microlithiasis (TM) and its severity with testicular dysfunction in men from infertile couples?

Summary Answer: The presence of ≥5 testis microcalcifications per sonogram at the scrotal ultrasonography (US) of infertile males was associated with a more severe testicular dysfunction as compared to males with limited, or without, TM.

What Is Known Already: TM, representing an incidental finding in the scrotal US, is associated with male infertility and a higher risk for testicular cancer as compared to that in infertile males without TM. Still, there are unresolved questions on the relation between TM severity and testicular dysfunction in infertile men, as well as on the identification of risk factors for TM. Read More

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Imaging of primary testicular lymphoma with unusual intraabdominal spread along the spermatic cord and gonadal vein.

Radiol Case Rep 2021 Mar 17;16(3):419-424. Epub 2020 Dec 17.

Department of Radiodiagnosis and Interventional Radiology, VMMC and Safdarjung Hospital, Ring Road, New Delhi 110029, India.

Primary testicular lymphoma (PTL) is a rare Testicular neoplasm found in elderly patients. Imaging features in PTL presenting with contiguous involvement of spermatic cord and extension along gonadal vein have been rarely detailed before. We describe a case of a 50-year-old male who presented with complaints of scrotal swelling and abdominal discomfort. Read More

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Determining factors of renal dysfunction during cisplatin chemotherapy.

Exp Ther Med 2021 Jan 26;21(1):83. Epub 2020 Nov 26.

Department of Oncology, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Cisplatin remains one of the most active antineoplastic treatments used in oncology, being the most prestigious exponent of the golden age in chemotherapy at the end of the 20th century. This chemotherapeutic drug is used for curative or palliative treatments in testicular, ovarian, head and neck neoplasms, sarcomas and lymphomas. The limiting dose adverse effect of cisplatin is nephrotoxicity. Read More

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January 2021

Primary pancreatic lymphoma camouflaged under the umbrella of spectrum of neuroendocrine tumors in somatostatin receptor imaging.

World J Nucl Med 2020 Jul-Sep;19(3):306-309. Epub 2020 Jul 22.

Department of Nuclear Medicine and PET/CT, Apollo Hospitals, Chennai, Tamil Nadu, India.

Primary pancreatic lymphomas are very rare as compared to other pancreatic neoplasms. However, unlike carcinomas, pancreatic lymphoma is treatable with satisfactory cure rates. Somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) with Ga-DOTANOC is a well-established diagnostic modality in the management of neuroendocrine tumors (NETs). Read More

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Epizootic neoplasia in a managed population of Atlantic bumper fish, Chloroscombrus chrysurus (Osteichthyes: Carangidae), at a public aquarium.

J Fish Dis 2021 Apr 21;44(4):415-427. Epub 2020 Dec 21.

Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.

Advances in fish medicine and husbandry have increased the average lifespans of specimens in managed aquarium populations. As a result, an increased incidence and variety of neoplasia is expected. This work characterizes diverse neoplasms arising within a managed population of Atlantic bumper fish acquired via repeated collections from the Charleston Harbor region. Read More

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[Ultrasonographic and clinical features of common testicular germ cell tumors in children].

Zhonghua Nan Ke Xue 2020 Feb;26(2):143-148

Department of Ultrasound, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, China.

Objective: To study the ultrasonographic manifestations and clinical features of common pediatric testicular germ cell tumors (TGCT) in children.

Methods: We retrospectively analyzed the laboratory, ultrasonographic and clinical data on 92 children with TGCT diagnosed in Shanghai Children's Hospital from March 2013 to January 2019, and investigated the values of the serum alpha-fetoprotein (AFP) level and maximum diameter of tumors in the diagnosis of benign and malignant tumors using the ROC curve.

Results: Of the 92 cases of pediatric TGCT, 64 (69. Read More

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February 2020

Hyperandrogenism caused by ovarian Leydig cell tumour: finding the needle in a haystack.

BMJ Case Rep 2020 Dec 13;13(12). Epub 2020 Dec 13.

Medicine, Hospital Melaka, Bandar Melaka, Malaysia.

Leydig cell tumours (LCTs) of the ovary are rare ovarian tumours that usually present with hyperandrogenism. Conventional radiological imagings are helpful in localising these tumours. However, some tumours may be too small to be localised before curative surgical removal. Read More

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December 2020

Complete remission of Cdx-2 positive primary testicular carcinoid tumor: 10-years follow-up and literature review.

BMC Urol 2020 Dec 14;20(1):197. Epub 2020 Dec 14.

Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

Background: The neuroendocrine cells can cause a variety of malignancies throughout the human body known as the neuroendocrine tumors (NETs) or carcinoid tumors. The primary testicular carcinoid tumor (PTCT) accounts for less than 1% of the testicular neoplasms and for only 0.2% of all carcinoid tumors representing already a very rare neoplastic entity. Read More

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December 2020

Utility of Serum miR-371a-3p in Predicting Relapse on Surveillance in Patients with Clinical Stage I Testicular Germ Cell Cancer.

Eur Urol Oncol 2021 Jun 4;4(3):483-491. Epub 2020 Dec 4.

Departments of Surgery (Urology), Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada. Electronic address:

Background: Optimal management of clinical stage I (CSI) testicular cancer is controversial due to lack of robust prognostic factors; miRNA-371a-3p holds promise as a biomarker, although its clinical utility for identifying patients at risk of relapse is unknown.

Objective: To explore the association between serum miR-371a-3p and CSI surveillance relapse.

Design, Setting, And Participants: Serial banked sera from 151 CSI (101 seminomas and 50 nonseminomatous germ cell tumors [NSGCTs]) samples from our Princess Margaret active surveillance cohort were tested. Read More

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