3,085 results match your criteria Malignant Testicular Tumor Imaging


[18F-FDG PET/CT features on paraganglioma of testis with multiple lymph node and lung metastasis: A case report and literature review].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Oct;43(10):1164-1168

PET/CT Center, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Objective: To determine the clinicopathological and imaging features in 18F-fluoro-2-deoxyglucose (18F-FDG) positron emission tomography and computed tomography (PET/CT) for paraganglioma of testis, and to increase the diagnostic accuracy.
 Methods: A case of paraganglioma of testis with multiple lymph node and lung metastasis were reported. PET/CT and pathological findings in the case were retrospectively analyzed. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.10.019DOI Listing
October 2018
1 Read

Serum tumor markers and testicular germ cell tumors: a primer for radiologists.

Abdom Radiol (NY) 2018 Dec 11. Epub 2018 Dec 11.

University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH, 44106, USA.

Serum tumor markers (STMs) play a critical role in the diagnosis, staging and follow-up of both seminomatous and nonseminomatous testicular germ cell neoplasms. Levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH), especially those measured after orchiectomy, also have implications for patient prognosis. Given that testicular germ cell tumors represent the most common solid tumor in men aged 20-34, radiologists must have familiarity with the clinical utilization and implications of these STMs. Read More

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http://dx.doi.org/10.1007/s00261-018-1846-zDOI Listing
December 2018
15 Reads

Thymic inflammatory pseudotumor with multilocular thymic cyst caused by immunoglobulin G4-related disease.

Thorac Cancer 2019 Jan 23;10(1):116-119. Epub 2018 Nov 23.

Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

A 44-year-old man was referred to our hospital after an anterior mediastinal tumor was noted on computed tomography during follow-up observation after left testicular seminoma resection. Chest computed tomography revealed an enhanced mass measuring 33 x 16 x 15 mm at the anterior mediastinum. Chest magnetic resonance imaging revealed high signal intensity on T2-weighted imaging, and F  fluorodeoxyglucose-positron emission tomography showed a maximum standardized uptake of 12. Read More

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http://dx.doi.org/10.1111/1759-7714.12914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312835PMC
January 2019
16 Reads

MR Imaging of the Testicular and Extratesticular Tumors: When Do We Need?

Magn Reson Imaging Clin N Am 2019 Feb 29;27(1):151-171. Epub 2018 Oct 29.

Section of Body Imaging, Yale School of Medicine, 20 York Street, PO Box 208042, New Haven, CT 06520-8042, USA.

Testicular ultrasound is typically the first-line imaging examination in evaluating scrotal pathology. However, MR imaging can often provide valuable additional information, especially when ultrasound and/or clinical examinations are inconclusive. This is particularly evident when encountering testicular or paratesticular lesions, where accurate localization and characterization are paramount for management and prognosis. Read More

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http://dx.doi.org/10.1016/j.mric.2018.08.006DOI Listing
February 2019
14 Reads

The use of F-FDG PET/CT in testicular cancer.

Transl Androl Urol 2018 Oct;7(5):875-878

Department of Urology, University Hospital Mainz, Mainz, Germany.

Testicular germ cell tumors are one of the most common neoplasms in young men. After inguinal orchiectomy is performed, treatment options range from active surveillance to chemotherapy, radiation therapy or retroperitoneal lymphadenectomy. For the accurate use of the different treatment options, precise imaging techniques are necessary to reduce side effects of the aggressive therapies but also to avoid undertreatment exposing the patient to the risk of recurrence. Read More

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http://dx.doi.org/10.21037/tau.2018.09.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212617PMC
October 2018
10 Reads

Lymph node imaging in testicular cancer.

Transl Androl Urol 2018 Oct;7(5):864-874

Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Testicular cancer is a rare malignancy mainly affecting young men. Survival for testicular cancer remains high due to the effectiveness of multimodal treatment options. Accurate imaging is imperative to both treatment and follow-up. Read More

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http://tau.amegroups.com/article/view/20740/21410
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http://dx.doi.org/10.21037/tau.2018.07.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212624PMC
October 2018
14 Reads

Molecular Imaging for Evaluation of Viable Testicular Cancer Nodal Metastases.

Curr Urol Rep 2018 Nov 9;19(12):110. Epub 2018 Nov 9.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Marburg 144, Baltimore, MD, 21287, USA.

Purpose Of Review: Determining the metastatic viability of suspicious retroperitoneal nodes in testicular cancer with conventional imaging is challenging. The aim of this report is to review recent evidence in the utilization of novel imaging modalities to assess viable testicular cancer nodal metastases.

Recent Evidence: Testicular germ cell tumors (TCGTs) follow a predictable lymphatic metastatic spread to the retroperitoneum. Read More

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http://link.springer.com/10.1007/s11934-018-0863-3
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http://dx.doi.org/10.1007/s11934-018-0863-3DOI Listing
November 2018
13 Reads

Adult testicular granulosa cell tumour: an extremely rare entity.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Urology Department, Centro Hospitalar do Porto, Porto, Portugal.

Adult granulosa cell tumours are extremely rare and usually benign but sometimes can assume an aggressive behaviour. A 31-year-old man presented with a 45 mm testicular mass. Radical orchiectomy was performed. Read More

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http://dx.doi.org/10.1136/bcr-2018-226316DOI Listing
November 2018
1 Read

MRI of testicular malignancies.

Abdom Radiol (NY) 2018 Nov 1. Epub 2018 Nov 1.

Department of Clinical Radiology, Medical School, University of Ioannina, University Campus, 45110, Ioannina, Greece.

Although testicular carcinoma represents approximately only 1% of solid neoplasms in men, it is the most common malignancy between young men. The two main histologic categories are testicular germ cell tumors (TGCTs), including seminomas and nonseminomas, accounting for 90-95% of testicular neoplasms and sex cord-stromal tumors. Scrotal MRI, including a multiparametric protocol, has been proposed as a valuable supplemental imaging technique in the investigation of testicular pathology. Read More

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http://dx.doi.org/10.1007/s00261-018-1816-5DOI Listing
November 2018
6 Reads

[French ccAFU guidelines - Update 2018-2020: Penile cancer].

Prog Urol 2018 Nov 22;28(12S):S131-S146. Epub 2018 Oct 22.

Comité de cancérologie de l'Association française d'urologie, groupe organes génitaux externes, maison de l'urologie, 11, rue Viète, 75017 Paris, France; Service d'urologie, hôpital européen Georges-Pompidou, université Paris Descartes, AP-HP, 75015 Paris, France.

Objective: To update French oncology guidelines concerning penile cancer.

Methods: Comprehensive Medline search between 2016 and 2018 upon diagnosis, treatment and follow-up of testicular germ cell cancer to update 2016-2018 guidelines. Level of evidence was evaluated according to AGREE-II. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11667087183046
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http://dx.doi.org/10.1016/j.purol.2018.08.001DOI Listing
November 2018
7 Reads

Sertoli-Leydig cell tumors of ovary: A case series.

Medicine (Baltimore) 2018 Oct;97(42):e12865

Pathology Department, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China.

Introduction: The purpose of this study was to report the clinical features, computed tomography (CT) and magnetic resonance imaging (MRI) findings, clinical management, and prognoses of 7 patients with Sertoli-Leydig cell tumors (SLCT) of ovary, and to review the literature of this rare condition.

Methods: Seven patients with pathologically confirmed ovarian SLCT were included. Their clinical, CT and MRI characteristics (CT images obtained from 6 patients and MR images from 4 patients), clinical management, and prognoses of 7 patients were retrospectively analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000012865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211859PMC
October 2018
6 Reads

Advanced colorectal carcinoma with testicular metastasis in an adolescent: a case report.

J Med Case Rep 2018 Oct 11;12(1):304. Epub 2018 Oct 11.

Department of Cardiovascular Radiology, AIIMS, New Delhi, India.

Background: Colorectal carcinoma in the pediatric age group is rare and tends to be very aggressive and present late, due to which it has a very poor prognosis. It may present with distant metastasis; however, metastasis to the testes is very rare and signifies an advanced stage of the disease. Surgery is the only effective modality to cure patients with localized colorectal carcinomas. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1831-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180440PMC
October 2018
7 Reads

[Tunica albuginea adenomatoid tumor. A challenging case managed conservatively].

Rev Int Androl 2018 Apr - Jun;16(2):82-86. Epub 2017 May 2.

Anatomia Patológica, Laboratório Anatomia Patológica (LAP), Porto, Portugal.

The adenomatoid tumors are rare benign mesothelial lesions that in males affect mainly the epididymis. They account for over one third of paratesticular tumors, and the treatment of choice has been surgical excision. The origin in testicular parenchyma or the tunica albuginea is extremely rare. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1698031X173003
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http://dx.doi.org/10.1016/j.androl.2017.02.008DOI Listing
May 2017
2 Reads

Ultrasonographic features of testicular metastasis from renal clear cell carcinoma that mimics a seminoma: A case report.

Medicine (Baltimore) 2018 Oct;97(40):e12728

Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Rationale: Testicular metastases from renal cell carcinoma (RCC) are extremely rare. To the best of our knowledge, only 35 cases have been described in the literatures.

Patient Concerns: A 64-year-old male presented to our urology clinic for a palpable painless mass on his right side of the scrotum by self-examination 1 week ago, with a general abdominal ultrasonographic report showing a mass in his right kidney. Read More

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http://dx.doi.org/10.1097/MD.0000000000012728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200504PMC
October 2018
6 Reads

Borderline Mucinous Testicular Tumour: Diagnostic and Management difficulties.

BMJ Case Rep 2018 Oct 3;2018. Epub 2018 Oct 3.

Department of Urology, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

A 45-year-old man presented with right-sided testicular swelling and pain. An examination found a tender, firm right testis, a clinically normal left testis and no palpable lymphadenopathy. Tumour and inflammatory markers were within normal limits. Read More

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http://dx.doi.org/10.1136/bcr-2017-223787DOI Listing
October 2018
5 Reads

Successful management of a patient with radiological presentation of choriocarcinoma syndrome before induction chemotherapy.

J Cancer Res Ther 2018 Sep;14(Supplement):S803-S805

Department of Urology and Andrology, Graduate School of Medicine, Kansai Medical University, Osaka, Japan.

Choriocarcinoma syndrome is a life-threatening lysis syndrome caused by blood vessel rupture and subsequent tumor bleeding. We describe a case of pretreatment choriocarcinoma syndrome that developed in a 27-year-old man. He underwent a high orchiectomy at a local hospital and was diagnosed with metastatic testicular tumor given the high serum human chorionic gonadotropin levels (943,601 mIU/mL). Read More

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http://www.cancerjournal.net/text.asp?2018/14/10/803/175433
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http://dx.doi.org/10.4103/0973-1482.175433DOI Listing
September 2018
16 Reads

Structural renal abnormalities in the DICER1 syndrome: a family-based cohort study.

Pediatr Nephrol 2018 Dec 3;33(12):2281-2288. Epub 2018 Sep 3.

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, 20850, USA.

Background: The DICER1 syndrome is a tumor-predisposition disorder caused by germline pathogenic variation in DICER1 and is associated with cystic nephroma and other renal neoplasms. Dicer1 mouse and rare human DICER1 syndrome case reports describe structural kidney and collecting system anomalies. We investigated renal function and the frequency of structural abnormalities of the kidney and collecting system in individuals with germline loss-of-function variants in DICER1. Read More

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http://link.springer.com/10.1007/s00467-018-4040-1
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http://dx.doi.org/10.1007/s00467-018-4040-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203641PMC
December 2018
17 Reads

Diagnosis and Treatment of Paratesticular Adenomatoid Tumors.

J Coll Physicians Surg Pak 2018 Sep;28(9):S217-S219

Department of Urology, Haydarpasa Numune Research and Training Hospital, Istanbul, Turkey.

Paratesticular adenomatoid tumor (PAT) is the most common paratesticular tumor. It is still a concern for today's urologists because it cannot be distinguished from malignant testicular tumors by clinical symptoms, routine examination and imaging methods. Because of the predominant benign nature of paratesticular masses, testicular preservative treatments get to the foreground. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.09.S217DOI Listing
September 2018
4 Reads

Mediastinal metastasectomy from a primary germ cell testicular tumour resulting in occult thoracic duct injury and chylothorax.

BMJ Case Rep 2018 Aug 17;2018. Epub 2018 Aug 17.

Cardiothoracic Surgery, Fiona Stanley Hospital, Perth, Western Australia, Australia.

A 22-year-old man underwent mediastinal metastasectomy for a testicular germ cell tumour via median sternotomy. Intraoperatively, the tumour was massive, measuring 88 mm in anterior-posterior (AP) diameter. It was densely adherent to the trachea and aggressive debulking resulted in tracheal injury. Read More

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http://dx.doi.org/10.1136/bcr-2018-225715DOI Listing
August 2018
10 Reads

Colour Doppler ultrasound imaging of blood flows variations in neoplastic and non-neoplastic testicular lesions in dogs.

Reprod Domest Anim 2019 Jan 25;54(1):63-71. Epub 2018 Sep 25.

Department of Veterinary Science, University of Parma, Parma, Italy.

Testicular tumours are the most common neoplasms in male dogs accounting for approximately 90% of all tumours affecting the genitourinary tract. Gray-scale ultrasonography in combination with colour and power Doppler imaging has been well accepted as an accurate technique for assessing scrotal lesions and vascularization of the testis. Colour Doppler sensitivity for low blood flows appears promising in the study of testicular disorders. Read More

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http://dx.doi.org/10.1111/rda.13310DOI Listing
January 2019
1 Read

Renal germ cell metastatic tumour with rupture, bleeding and syncope: an unusual clinical presentation in a young patient.

BMJ Case Rep 2018 Aug 9;2018. Epub 2018 Aug 9.

Urology, University Hospital "Ospedali Riuniti", Ancona, Italy.

The most common malignancy in young men is a germ cell tumour of the testes. Metastatic renal disease is relatively uncommon and usually manifests in the retroperitoneal lymph nodes. Visceral metastases to the liver, and metastases to the lungs and the brain are more common. Read More

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http://dx.doi.org/10.1136/bcr-2017-223990DOI Listing
August 2018
12 Reads

Testicular cavernous hemangioma associated with testicular torsion - case report and review of literature.

Int J Surg Case Rep 2018 27;49:247-250. Epub 2018 Jun 27.

Department of Pediatric and Adolescent Surgery, General Hospital, Klagenfurt, Austria. Electronic address:

Introduction: Testicular neoplasms that are derived from connective tissue, blood vessels and musculature are uncommon and intra-testicular tumors of vascular origin are extremely rare; both are benign in nature. Testicular hemangioma is exceedingly rare and typically occurs in patients younger than 20 years, the age in which a primary germ cell tumor of the testis may present, necessitating a radical approach to management with orchidectomy, although potential conservative focal partial surgical excision is desirable. Hemangiomas of the testis have a similar sonographic and magnetic resonance imaging appearance to that of malignant tumors of the testis, especially seminoma. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080632PMC
June 2018
3 Reads

Biochemical Recurrence of Prostate Cancer Presenting as Solitary Testicular Metastasis on 68Ga-Labeled Prostate-Specific Membrane Antigen Ligand Positron Emission Tomography/Computed Tomography.

Clin Nucl Med 2018 Sep;43(9):699-700

From the Departments of Nuclear Medicine.

Prostate adenocarcinoma (PCa) is the most frequently diagnosed malignancy in the male population, with the most common sites for secondary lesions being the lymph nodes, bones, and lungs. Testicular metastases from PCa are very rare and mostly identified incidentally after therapeutic orchiectomy for advanced PCa or during autopsy. Here we present a case involving a 64-year-old man with biochemical recurrence of castrated oligometastatic PCa that presented as solitary testicular metastasis on Ga-PSMA ligand positron emission tomography/computed tomography. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002204DOI Listing
September 2018
18 Reads

Sertoliform endometrioid carcinoma of the ovary in a young female.

Indian J Pathol Microbiol 2018 Jul-Sep;61(3):459-460

Department of Pathology, Shrimati Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.

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http://dx.doi.org/10.4103/IJPM.IJPM_675_17DOI Listing
January 2019
2 Reads

Spermatocytic seminoma with rhabdomyoblastic differentiation: Case report and review of literature.

Indian J Pathol Microbiol 2018 Jul-Sep;61(3):437-439

Department of Pathology, HBT Medical College and Dr. R. N. Cooper Municipal General Hospital, Mumbai, Maharashtra, India.

Spermatocytic seminoma (SCS) is an indolent germ cell tumor of the testis. It has an excellent prognosis and orchidectomy is generally curative. Very rarely, it can be complicated by a sarcomatous transformation which is associated with a very aggressive behavior and requires adjuvant therapy. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_243_17DOI Listing
November 2018
2 Reads

[Beta-hCG-producing thymic teratoma: an uncommon cause of peripheral precocious puberty].

Rev Chil Pediatr 2018 Jun;89(3):373-379

Servicio de Pediatría, Hospital Dr. Hernán Henríquez Aravena, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.

Introduction: Among the causes of peripheral precocious puberty in men are the beta-human cho rionic gonadotropin (Β-HCG)-secreting tumors, such as hepatoblastomas, dysgerminomas, chorio carcinomas, and immature teratomas. In pediatrics, the mediastinal teratomas are rare, representing the 7-10% of extragonadal teratomas.

Objective: To describe the case of a patient with peripheral precocious puberty due to a Β-HCG -secreting thymic teratoma. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000304DOI Listing
June 2018
14 Reads

[Pathologic features on gonadal changes of sexual developmental disorders in children].

Zhonghua Bing Li Xue Za Zhi 2018 Jul;47(7):531-535

Department of Pediatric Endocrinology, Guangzhou Women and Children's Medical Center, Guangzhou 510623, China.

To investigate the pathologic features of gonadal tissues of disorders of sexual development (DSD) in children. Fifty-three cases of gonadal developmental disorders were collected from July 2015 to August 2017 at Guangzhou Women and Children's Medical Center. Clinical manifestations, karyotypes, sex hormone levels, ultrasound imaging, histology and immunophenotype of gonadal tissues were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.07.010DOI Listing
July 2018
20 Reads

Peritoneal Myeloid Sarcoma in a Patient Treated for a Testicular Seminoma.

Am J Case Rep 2018 Jun 29;19:763-766. Epub 2018 Jun 29.

Division of Medical Oncology, Mercy Hospital, Metz-Thionville Regional Hospital Center, Ars-Laquenexy, France.

BACKGROUND Myeloid sarcoma is a rare extramedullary soft tissue neoplasm composed of myeloblastic cells, usually associated to hematologic tumor disorders and a poor prognosis. Its diagnosis is very difficult as radiological images are not specific. Histology and immunohistochemistry are necessary for an accurate diagnosis. Read More

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https://www.amjcaserep.com/abstract/index/idArt/910434
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http://dx.doi.org/10.12659/AJCR.910434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055577PMC
June 2018
7 Reads

Alveolar paratesticular rhabdomyosarcoma mimicing epididymitis: Case report and literature review.

Medicine (Baltimore) 2018 06;97(25):e11164

Department of Urology, The First Hospital of Quanzhou Affiliated to Fujian Medical University.

Rationale: Most patients with paratesticular rhabdomyosarcoma may typically present as a unilateral, painless palpable scrotum mass. However, only a few cases of RMS presenting as painful edema of the scrotum mimicing epididymitis. We herein report an unusual case of alveolar paratesticular rhabdomyosarcoma misdiagnosed as epididymitis. Read More

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http://dx.doi.org/10.1097/MD.0000000000011164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024466PMC
June 2018
7 Reads

Management of testicular Leydig cell tumor: A case report.

Medicine (Baltimore) 2018 Jun;97(25):e11158

Department of Radiology, the Second Affiliated Hospital of Nanjing Medical University.

Rationale: Testicular Leydig cell tumor (LCT) is a rare neoplasm. It commonly presents as a painless testicular mass with or without endocrine changes. Histological and immunohistochemical examination play important roles in differentiating LCT from testicular germ cell tumors. Read More

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http://dx.doi.org/10.1097/MD.0000000000011158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023788PMC
June 2018
11 Reads

Retroperitoneal seminoma, a rare cause of testicular pain.

BMJ Case Rep 2018 Jun 14;2018. Epub 2018 Jun 14.

Department of General Surgery, Royal Free London NHS Foundation Trust, London, London, UK.

Extragonadal retroperitoneal seminomas are a rare cause of testicular pain in males. We report the case of a 46-year-old man, who presented with right-sided testicular pain, clinically mimicking testicular torsion. The patient underwent a scrotal exploration, which revealed normal testes. Read More

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http://dx.doi.org/10.1136/bcr-2017-223736DOI Listing
June 2018
5 Reads

Symptomatic hyperthyroidism in metastatic testicular mixed germ cell tumour.

BMJ Case Rep 2018 Jun 8;2018. Epub 2018 Jun 8.

Internal Medicine, Rochester General Hospital, Rochester, New York, USA.

This is a case of a young 34-year-old man who had symptomatic hyperthyroidism from an extremely high serum beta HCG level in the setting of a metastatic stage IIIC mixed germ cell tumour. The patient's thyroid function normalised with treatment of the cancer as the beta HCG levels declined. Read More

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http://dx.doi.org/10.1136/bcr-2018-224877DOI Listing
June 2018
3 Reads

Testicular toxoplasmosis in a 26-year-old immunocompetent man.

BMJ Case Rep 2018 Jun 4;2018. Epub 2018 Jun 4.

McGaw Medical Center of Northwestern University, Chicago, Illinois, USA.

Testicular toxoplasmosis is a very rare presentation of A 26-year-old immunocompetent man presented to us with right testicular pain and a right epididymal mass. Ultrasound was concerning for malignancy and a radical orchiectomy was performed. Surgical pathology revealed chronic granulomatous inflammation which stained positive for . Read More

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http://dx.doi.org/10.1136/bcr-2018-224962DOI Listing
June 2018
2 Reads

Testicular plasmacytoma misdiagnosed as orchitis.

BMJ Case Rep 2018 Jun 4;2018. Epub 2018 Jun 4.

Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Testicular plasmacytomas are rare, accounting for only 1.3% of all extramedullary plasmacytomas. The infrequency in which it is encountered, coupled with its non-specific clinical and sonographic presentation, makes its diagnosis a challenge. Read More

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http://dx.doi.org/10.1136/bcr-2017-222046DOI Listing
June 2018
6 Reads

Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review.

Medicine (Baltimore) 2018 Jun;97(22):e10736

Department of Urology, the First Affiliated Hospital of GuangXi Medical University.

Rationale: Cutaneous metastasis of testicular choriocarcinoma is exceptionally uncommon. To our knowledge, only 14 cases have been reported in the past 10 years in the pubmed. We have an uncommon case of testicular choriocarcinoma who has metastasized to the adjacent skin and organ systems. Read More

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http://dx.doi.org/10.1097/MD.0000000000010736DOI Listing
June 2018
4 Reads

Giant intrascrotal embryonal rhabdomyosarcoma in an adult: a case report and review of the literature.

J Med Case Rep 2018 May 28;12(1):149. Epub 2018 May 28.

Department of Andrology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.

Background: Intrascrotal embryonal rhabdomyosarcoma in adults is a rare tumor with high aggression and a poor prognosis. We report our patient's case and review the relevant literature to improve the understanding of this rare disease.

Case Presentation: A 21-year-old Han Chinese man presented to our hospital with a right intrascrotal mass of 1 year's duration. Read More

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http://dx.doi.org/10.1186/s13256-018-1607-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971421PMC
May 2018
1 Read

Spectrum of Extratesticular and Testicular Pathologic Conditions at Scrotal MR Imaging.

Radiographics 2018 May-Jun;38(3):806-830

From the Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Rd NE, Atlanta, GA 30322 (P.K.M., D.A.B., P.A.H., J.P., C.C.M.); Department of Clinical Imaging, Hamad Medical Corporation, Doha, Qatar (A.S.A.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (A.C., H.G., F.H.M.).

Diagnostic workup of scrotal lesions should begin with a complete clinical history and physical examination, including analysis of risk factors such as family history of testicular cancer, personal history of tumor in the contralateral testis, and cryptorchidism, followed by imaging. Scrotal ultrasonography (US) with a combination of gray-scale and color Doppler techniques has been the first-line imaging modality for evaluation of testicular and extratesticular lesions because of its low cost, wide availability, and high diagnostic accuracy. However, US has limitations related to operator dependence, the relatively small field of view, and lack of tissue characterization. Read More

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http://dx.doi.org/10.1148/rg.2018170150DOI Listing
October 2018
5 Reads

[Advances in the studies of testicular microlithiasis].

Zhonghua Nan Ke Xue 2017 Aug;23(8):734-738

Department of Andrology, Drum Tower Hospital / Gulou School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu 210008, China.

With the increased attention to men's health and development of ultrasound imaging technology, clinicians are achieving a better understanding of testicular microlithiasis. This review presents an overview on recent studies of the etiology, pathogenesis, and imaging characteristics of testicular microlithiasis, its impact on male reproductive function, and its relation ship with testis tumors and other related diseases, as well as its treatment strategies and follow-up proposals, aiming to provide some new evidence for further understanding and management of the disease. Read More

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August 2017
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Spontaneous rupture of seminoma in undescended testis with hemoperitoneum: a rare presentation.

BMJ Case Rep 2018 Apr 19;2018. Epub 2018 Apr 19.

General Surgery, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, Delhi, India.

Cryptorchidism is associated with increased risk of malignancy and infertility. We present a case of a 30-year-old man who presented to the Emergency Department of our tertiary care hospital with spontaneous intra-abdominal rupture of the seminoma in undescended testis with hemoperitoneum. This is a rare presentation of seminoma and emphasises the importance of scrotal examination in young men presenting with acute abdomen. Read More

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http://dx.doi.org/10.1136/bcr-2018-224898DOI Listing
April 2018
5 Reads

Outcomes of active surveillance of clinical stage I non-seminomatous germ cell tumors: sub-analysis of the multi-institutional nationwide case series of the Japanese Urological Association.

Jpn J Clin Oncol 2018 Jun;48(6):565-569

Urology Division, National Cancer Center Hospital, Tokyo, Japan.

Objective: To evaluate the survival rate and risk factors of distant metastasis in stage I non-seminomatous germ cell tumor (NSGCT) cases without adjuvant treatments.

Methods: A national testicular cancer survey of cases newly diagnosed in 2005 and 2008 was conducted by the Japanese Urological Association in 2011. In 159 stage I NSGCT cases, 132 were followed by active surveillance after high orchiectomy. Read More

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http://dx.doi.org/10.1093/jjco/hyy051DOI Listing
June 2018
4 Reads

Testicular Cancer: Diagnosis and Treatment.

Am Fam Physician 2018 Feb;97(4):261-268

Fort Polk, LA, USA.

Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include undescended testis (cryptorchidism), personal or family history of testicular cancer, age, ethnicity, and infertility. Read More

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February 2018
6 Reads

Paratesticular Serous Papillary Carcinoma of High Grade and Malignant Potential: A Rare Case with a Role for Adjuvant Therapy.

Cureus 2018 Feb 13;10(2):e2188. Epub 2018 Feb 13.

Department of Urology, Keck School Of Medicine at USC.

Paratesticular serous papillary carcinomas are very rare, with less than 40 cases reported in the literature. These neoplasms are Müllerian in origin, and more commonly seen as epithelial-type ovarian cancer. Given the rarity of this tumor in men, staging and recommended treatment options do not exist. Read More

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http://dx.doi.org/10.7759/cureus.2188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898837PMC
February 2018
5 Reads

Sonographic Appearance of Testicular Adrenal Rest Tumour in a Patient with Congenital Adrenal Hyperplasia.

Pol J Radiol 2017 15;82:526-529. Epub 2017 Sep 15.

Department of Radiodiagnosis, Topiwala National Medical College and B.Y.L. Nair Hospital, Mumbai, India.

Background: Testicular adrenal rest tumours (TARTs) are benign testicular masses that are found in inadequately treated patients with congenital adrenal hyperplasia (CAH). Recognizing this association and identifying characteristic ultrasound features of TARTs is important so as to avoid misdiagnosing them as malignancies, which can lead to unnecessary interventions.

Case Report: We describe a case of a 9-year-old boy, with a diagnosis of CAH and precocious puberty, who was referred to our department for an ultrasound evaluation of the abdomen and scrotum. Read More

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https://www.termedia.pl/doi/10.12659/PJR.902013
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http://dx.doi.org/10.12659/PJR.902013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894002PMC
September 2017
4 Reads

Using microscope for onco-testicular sperm extraction for bilateral testis tumors.

Fertil Steril 2018 04;109(4):745

Department of Urology, University of Miami Miller School of Medicine, Miami, Florida; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.

Objective: To demonstrate a step-by-step approach to the use of the operating microscope for onco-testicular sperm extraction.

Design: Video presentation.

Setting: University hospital. Read More

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http://dx.doi.org/10.1016/j.fertnstert.2018.01.016DOI Listing
April 2018
5 Reads
4.590 Impact Factor

[Non-palpable testicular tumors in adults: A management based on imaging? Issue from the French Urologic Association Genital Cancer committee's edit].

Prog Urol 2018 Jun 9;28(8-9):407-415. Epub 2018 Apr 9.

Hôpital IA Begin/Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris, France.

Background: Help in management of non-palpable testicular tumors. French Urologic Association Genital cancer committee's Edit.

Objectives: To review their characterization at imaging findings of non-palpable testicular tumors. Read More

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http://dx.doi.org/10.1016/j.purol.2018.03.007DOI Listing
June 2018
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Ultrasound Appearances of Pediatric Testicular Yolk Sac Tumors: Twenty-one Cases in a Single Institution.

Authors:
Qing-Da Song

J Ultrasound Med 2018 Oct 10;37(10):2457-2463. Epub 2018 Apr 10.

Department of Ultrasound, Shandong Medical Imaging Research Institute, Shandong University, Jinan, China.

Testicular yolk sac tumors are rare, and analyses of relevant ultrasound (US) findings are limited. We retrospectively reviewed the US features of 21 pathologically verified cases (patients aged 10-64 months). Neoplasms were unilateral and solitary, occupying part (focal) or all (diffuse) of the testis. Read More

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http://dx.doi.org/10.1002/jum.14597DOI Listing
October 2018
8 Reads

Subphenotype meta-analysis of testicular cancer genome-wide association study data suggests a role for RBFOX family genes in cryptorchidism susceptibility.

Hum Reprod 2018 05;33(5):967-977

Nemours Biomedical Research/Alfred I. duPont Hospital for Children, Wilmington, DE, USA.

Study Question: Can subphenotype analysis of genome-wide association study (GWAS) data from subjects with testicular germ cell tumor (TGCT) provide insight into cryptorchidism (undescended testis, UDT) susceptibility?

Summary Answer: Suggestive intragenic GWAS signals common to UDT, TGCT case-case and TGCT case-control analyses occur in genes encoding RBFOX RNA-binding proteins (RBPs) and their neurodevelopmental targets.

What Is Known Already: UDT is a strong risk factor for TGCT, but while genetic risk factors for TGCT are well-known, genetic susceptibility to UDT is poorly understood and appears to be more complex.

Study Design, Size, Duration: We performed a secondary subphenotype analysis of existing GWAS data from the Testicular Cancer Consortium (TECAC) and compared these results with our previously published UDT GWAS data, and with data previously acquired from studies of the fetal rat gubernaculum. Read More

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http://dx.doi.org/10.1093/humrep/dey066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925768PMC
May 2018
19 Reads

Changes in Brain Structural Networks and Cognitive Functions in Testicular Cancer Patients Receiving Cisplatin-Based Chemotherapy.

J Natl Cancer Inst 2017 12;109(12)

Unit for Psychooncology and Health Psychology, Department of Oncology and Department of Psychology and Behavioural Sciences, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.

Background: Cisplatin-based chemotherapy may have neurotoxic effects within the central nervous system. The aims of this study were 1) to longitudinally investigate the impact of cisplatin-based chemotherapy on whole-brain networks in testicular cancer patients undergoing treatment and 2) to explore whether possible changes are related to decline in cognitive functioning.

Methods: Sixty-four newly orchiectomized TC patients underwent structural magnetic resonance imaging (T1-weighted and diffusion-weighted imaging) and cognitive testing at baseline prior to further treatment and again at a six-month follow-up. Read More

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http://dx.doi.org/10.1093/jnci/djx085DOI Listing
December 2017
43 Reads

Testicular Yolk Sac Tumor and Mature Teratoma: Synchronous Bilateral Occurrence in an Infant.

Urology 2018 Jul 30;117:142-144. Epub 2018 Mar 30.

Department of Ultrasound, Tianjin Children's Hospital, Tianjin, China.

Yolk sac tumor (YST) is a rare malignancy typically occurring in children. However, bilateral testicular YSTs are a quite rare situation, which can occur metachronously or synchronously with same histologic type, as well as different histology. We present a case of synchronous YST of the left testis and mature teratoma of the right in a 7-month-old infant treated with testis-sparing surgery at right testis and high radical orchiectomy at left. Read More

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http://dx.doi.org/10.1016/j.urology.2018.03.025DOI Listing
July 2018
19 Reads

Large intra-abdominal seminoma in a left undescended testicle complicated by torsion.

BMJ Case Rep 2018 Mar 28;2018. Epub 2018 Mar 28.

Department of Urology, University of Texas Health Science Center, San Antonio, Texas, USA.

A 39-year-old man presented with a 2-day history of worsening constant, dull diffuse lower abdominal pain with associated constipation and known history of left undescended testicle. He was evaluated at an outside hospital where a non-contrasted CT scan revealed a 20 cm well-circumscribed soft tissue mass within the pelvis.He was referred and further imaging revealed a 12 cm heterogeneous mass with foci of air that appeared to be contiguous with the left spermatic cord. Read More

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http://dx.doi.org/10.1136/bcr-2017-222670DOI Listing
March 2018
7 Reads