209 results match your criteria Malassezia Pityrosporum Folliculitis


Malassezia virulence factors and their role in dermatological disorders.

Acta Dermatovenerol Alp Pannonica Adriat 2022 Jun;31(2):65-70

Department of Biochemistry, Faculty of Medicine and Health Sciences, Christian University of Krida Wacana (UKRIDA), Jakarta, Indonesia.

Malassezia is a commensal fungus that constitutes normal skin microbiota. However, in certain conditions and individuals, it may transform into a pathogenic yeast with multiple associated dermatological disorders and various clinical manifestations. This phenomenon is influenced by a unique host-agent interaction that triggers the production of several virulence factors, such as indoles, reactive oxygen species, azelaic acid, hyphae formation, and biofilm formation. Read More

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Effectiveness of FastFung agar in the isolation of Malassezia furfur from skin samples.

Mycoses 2022 Jul 25;65(7):704-708. Epub 2022 May 25.

Department of Medical Microbiology, Medical Faculty, Cukurova University, Adana, Turkey.

Background: Lipophilic basidiomycetous yeasts of the Malassezia genus can cause various skin diseases, such as seborrheic dermatitis, pityriasis versicolor, folliculitis and atopic dermatitis, and even life-threatening fungemia in newborns and immunocompromised individuals. Routine mycological media used in clinical practice do not contain sufficient lipid ingredients required for the growth of Malassezia species. A recently developed medium, FastFung agar, is promising for culturing fastidious fungal species. Read More

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Difficulties in diagnosing Malassezia furfur bloodstream infection and possibility of spontaneous resolution in a patient undergoing chemotherapy for neuroblastoma: A case report.

J Infect Chemother 2022 Jul 9;28(7):987-990. Epub 2022 Mar 9.

Department of Infectious Diseases, Nagoya University Hospital, Aichi, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Aichi, Japan.

Malassezia furfur is a lipophilic, yeast-like fungus that forms part of the normal human skin microflora and is associated with a wide range of infections, such as pityriasis versicolor, folliculitis, and systemic infections in immunocompromised patients. Although matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has enabled rapid identification of Malassezia species, it is still a challenge to diagnose systemic infections because Malassezia fungemia can often be missed by automated blood culture systems. We report a case in which M. Read More

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Dermoscopy as an Auxiliary Tool in the Assessment of Malassezia Folliculitis: An Observational Study.

Actas Dermosifiliogr 2022 Jan 29;113(1):T78-T81. Epub 2021 Jun 29.

Department of Dermatology, NDMC Medical College & Hindu Rao Hospital, New Delhi, India.

Malassezia folliculitis is an under-recognized entity commonly affecting the face and upper trunk. Clinical picture mimics acne vulgaris and diagnosis is challenging at times. Ten percent potassium hydroxide examination is usually performed to confirm the diagnosis. Read More

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January 2022

Dermoscopy as an Auxiliary Tool in the Assessment of Malassezia Folliculitis: An Observational Study.

Actas Dermosifiliogr 2022 Jan 3;113(1):78-81. Epub 2022 Feb 3.

Department of Dermatology, NDMC Medical College & Hindu Rao Hospital, New Delhi, India.

Malassezia folliculitis is an under-recognizedentity commonly affecting the face and upper trunk. Clinical picture mimics acne vulgaris and diagnosis is challenging at times. 10% potassium hydroxide examination is usually performed to confirm the diagnosis. Read More

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January 2022

Atypical folliculitis caused by Malassezia spp. in immunosuppressed patients.

Bol Med Hosp Infant Mex 2022 ;79(1):62-68

Servicio de Anatomía Patológica Pediátrica, Unidad Médica de Alta Especialidad Hospital de Pediatría. Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Background: Folliculitis due to Malassezia spp. (MF), caused mainly by Malassezia furfur, is clinically characterized by an acneiform eruption expressing follicular papules and pustules, predominantly on the trunk. Diagnosis of MF requires confirmation of the presence of yeasts in the hair follicle. Read More

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Pityrosporum folliculitis in critically ill COVID-19 patients.

J Eur Acad Dermatol Venereol 2022 Mar 17;36(3):e186-e188. Epub 2021 Dec 17.

Department of Dermatology, Hospital de Clínicas de Porto Alegre - Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

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Immunophenotyping comparison of inflammatory cells between Malassezia folliculitis and pityriasis versicolor lesions.

Med Mycol 2021 Dec;60(1)

Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, China.

Immunophenotyping of inflammatory dermal infiltrates in Malassezia folliculitis (MF) and pityriasis versicolor (PV) lesions is less reported. Immunohistochemistry was performed on 21 MF lesions, 10 PV lesions, and 10 control skin. CD3+, CD4+, CD8+, CD20+, CD68+, and CD117+ cells were increased in MF compared with PV and normal skin (P < 0. Read More

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December 2021

Necrotizing infundibular (ostial) crystalline folliculitis.

Clin Dermatol 2021 Mar-Apr;39(2):194-198. Epub 2020 Oct 16.

Department of Pathology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address:

Necrotizing infundibular crystalline folliculitis is a rare condition characterized by folliculocentric waxy papules in the seborrheic areas of adult patients, with intrafollicular filamentous birefringent crystalline deposits as the histopathologic clue. Although the real pathogenesis of necrotizing infundibular crystalline folliculitis remains unclear, the intrafollicular material seems to be derived from an interaction between such superficial microorganisms as gram-positive bacteria (Propionibacterium acnes, Staphylococcus spp), Malassezia yeasts, and sebaceous lipids. Topical or systemic antiacne agents or antimycotics appear to be effective therapy. Read More

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November 2021

[Cutaneous complications following hematopoietic stem cell transplantation].

Bull Cancer 2021 Sep 8;108(9):877-885. Epub 2021 Jul 8.

CHU Ibn Rochd, service de dermatologie et de vénérologie, 1, rue des Hôpitaux, Casablanca, Maroc.

Background: Hematopoietic stem cell allograft is a treatment for patients with severe constitutional or acquired hematopoietic system diseases. This act is always linked to complications requiring multidisciplinary care. Our study describes the post-allograft cutaneous complications. Read More

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September 2021

Not all that glitters is COVID-19: a case series demonstrating the need for histopathology when skin findings accompany SARS-CoV-2 infection.

J Eur Acad Dermatol Venereol 2021 Sep 7;35(9):1865-1873. Epub 2021 Jun 7.

Department of Dermatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Background: Descriptions of cutaneous findings associated with COVID-19 have not been consistently accompanied by histopathology or confirmatory testing for SARS-CoV-2.

Objective: To describe and classify the cutaneous findings with supporting histopathology of confirmed COVID-19 inpatients.

Methods: We included consecutive inpatients with a confirmed diagnosis of COVID-19 for whom a dermatology consult was requested. Read More

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September 2021

Identification of species using direct PCR- sequencing on clinical samples from patients with pityriasis versicolor and seborrheic dermatitis.

Curr Med Mycol 2020 Sep;6(3):21-26

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background And Purpose: yeasts are lipophilic normal flora of the skin in humans and other warm-blooded vertebrates. This genus includes 18 species and is responsible for dermatological disorders, such as pityriasis versicolor, atopic dermatitis, seborrheic dermatitis, folliculitis, and dandruff. The aim of the present study was to identify the etiologic agents of infections among the patients referring to the Referral Dermatology Clinic of Al-Zahra Hospital, Isfahan, Iran, during 2018-2019. Read More

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September 2020

Malassezia (Pityrosporum) Folliculitis Masquerading As Recalcitrant Acne.

Cureus 2021 Feb 24;13(2):e13534. Epub 2021 Feb 24.

Internal Medicine, Narayana Superspeciality Hospital, Katra, IND.

Malassezia (Pityrosporum) folliculitis is a relatively common skin infection that affects the hair follicles. The condition is characterized by monomorphic perifollicular skin lesions and itching without comedones. Malassezia folliculitis significantly resembles acne vulgaris and steroid acne but is subtly distinct and managed differently. Read More

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February 2021

Host Responses in an Human Skin Model Challenged With .

Front Cell Infect Microbiol 2020 21;10:561382. Epub 2021 Jan 21.

School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

species are a major part of the normal mycobiota and colonize mainly sebum-rich skin regions of the body. This group of fungi cause a variety of infections such as pityriasis versicolor, folliculitis, and fungaemia. In particular, and its allergens have been associated with non-infective inflammatory diseases such as seborrheic dermatitis and atopic eczema. Read More

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Antagonistic Activity of Antimicrobial Metabolites Produced from Seaweed-Associated Bacillus amyloliquefaciens MTCC 10456 Against Malassezia spp.

Probiotics Antimicrob Proteins 2021 08 1;13(4):1228-1237. Epub 2021 Feb 1.

Praj-Matrix - R&D Centre (Division of Praj Industries Limited) 402/403/1098, Urawade, Pirangut, Mulshi, Pune, 412115, Maharashtra, India.

Members of the genus Malassezia are known to be opportunistic pathogens responsible for causing skin disorders such as seborrheic dermatitis or dandruff, pityriasis versicolor, folliculitis, atopic dermatitis, and psoriasis. Due to the side effects caused by prolonged use of current topical antifungal agents, development of an alternative treatment is necessary. Fermentative production of antimicrobial metabolites from Bacillus amyloliquefaciens MTCC 10456 was carried out, and their antagonistic activity against Malassezia furfur and Malassezia globosa was evaluated. Read More

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[Malassezia folliculitis].

Ugeskr Laeger 2020 11;182(47)

In this review, we discuss Malassezia folliculitis (MF), which is an inflammation in the hair follicles caused by different Malassezia species. The prevalence of MF in the population worldwide ranges from 1% to 17%. Clinically, it may be difficult to distinguish from acne vulgaris, as it presents as erythematous 2-4 mm large papules and pustules on the back, chest and neck. Read More

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November 2020

Inflammasome-mediated Inflammation by Malassezia in human keratinocytes: A comparative analysis with different strains.

Mycoses 2021 Mar 2;64(3):292-299. Epub 2020 Dec 2.

Department of Dermatology, College of Medicine, Eunpyeong St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Malassezia species are associated with several common dermatologic conditions including pityriasis versicolor, seborrhoeic dermatitis, folliculitis, and atopic dermatitis and dandruff. However, its causal role remains to be established. We intended to explore the role of inflammasome activation in human keratinocytes in response to three different Malassezia species. Read More

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Approaches for Genetic Discoveries in the Skin Commensal and Pathogenic Yeasts.

Front Cell Infect Microbiol 2020 7;10:393. Epub 2020 Aug 7.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States.

includes yeasts belong to the subphylum Ustilaginomycotina within the Basidiomycota. yeasts are commonly found as commensals on human and animal skin. Nevertheless, species are also associated with several skin disorders, such as dandruff/seborrheic dermatitis, atopic eczema, pityriasis versicolor, and folliculitis. Read More

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Susceptibilities of strains from pityriasis versicolor, Malassezia folliculitis and seborrheic dermatitis to antifungal drugs.

Heliyon 2020 Jun 20;6(6):e04203. Epub 2020 Jun 20.

Department of Dermatology, First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, 650032, Yunnan, China.

The human pathogenic yeast genus may be an etiological agent of skin disorders and has received considerable attention from dermatologists in recent years. To investigate the different susceptibilities of species to four antifungal drugs, we isolated a total of 244 strains and identified six species of from patients with clinical skin diseases. The minimum inhibitory concentration (MIC) of the four antifungal drugs was obtained by comparing the susceptibility of the isolated strains to four antifungal drugs (ketoconazole (KTZ), itraconazole (ITZ), fluconazole (FLC) and amphotericin B (Am B)). Read More

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as a Novelty Model of Host-Pathogen Interaction for CBS 1878 and CBS 1879.

Front Cell Infect Microbiol 2020 5;10:199. Epub 2020 May 5.

Grupo de Investigación Celular y Molecular de Microorganismos Patógenos (CeMoP), Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, Colombia.

and are lipophilic and lipid dependent yeasts, associated with the skin microbiota in humans and domestic animals, respectively. Although they are commensals, under specific conditions they become pathogens, causing skin conditions, such as pityriasis versicolor, dandruff/seborrheic dermatitis, folliculitis in humans, and dermatitis and otitis in dogs. Additionally, these species are associated with fungemia in immunocompromised patients and low-weight neonates in intensive care units with intravenous catheters or with parenteral nutrition and that are under-treatment of broad-spectrum antibiotics. Read More

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Diagnostic evaluation of a point-of-care test for culture and microbial susceptibility testing in canine dermatological infections in clinical practice.

Vet World 2020 Mar 20;13(3):521-529. Epub 2020 Mar 20.

Department of Veterinary Medicine (DIMEVET), University of Milan, via dell'Università 6, 26900 Lodi, Italy.

Background And Aim: Empirical antimicrobial therapy is frequently given in superficial bacterial folliculitis (SBF) and otitis externa (OE) in dogs, especially for the initial clinical presentation. Culture and subsequent antimicrobial susceptibility testing (AST) are generally limited to chronic cases with poor response to initial therapy. Several factors contribute to the failure to implement the use of AST in veterinary practice, i. Read More

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An update on pityrosporum folliculitis in Singapore from a single tertiary care dermatological centre.

Singapore Med J 2021 10 29;62(10):526-528. Epub 2020 Apr 29.

Division of Dermatology, University Medicine Cluster, National University Hospital, Singapore.

Introduction: Pityrosporum folliculitis (PF) is a common skin condition that can be easily misdiagnosed, especially by non-dermatologists. While the initial diagnosis is often made clinically, skin microscopy may help to confirm the same. However, there is scant literature regarding the clinical epidemiology of PF. Read More

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October 2021

Oral treatment with/without topical treatment vs topical treatment alone in Malassezia Folliculitis patients: A systematic review and meta-analysis.

Dermatol Ther 2020 05 8;33(3):e13460. Epub 2020 May 8.

Department of Dermatology and Venereology, 401 General Military Hospital of Athens, Athens, Greece.

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Treatment of Trametinib-Associated Folliculitis Eruption With Fluconazole.

JAMA Dermatol 2020 06;156(6):706-708

Department of Dermatology, University of North Carolina, Chapel Hill.

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-Associated Skin Diseases, the Use of Diagnostics and Treatment.

Front Cell Infect Microbiol 2020 20;10:112. Epub 2020 Mar 20.

St. Johns Institute of Dermatology, Kings College London, London, United Kingdom.

Yeasts of the genus, , formerly known as , are lipophilic yeasts, which are a part of the normal skin flora (microbiome). colonize the human skin after birth and must therefore, as commensals, be normally tolerated by the human immune system. The yeasts also have a pathogenic potential where they can, under appropriate conditions, invade the stratum corneum and interact with the host immune system, both directly but also through chemical mediators. Read More

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Clinical and histological recovery of non-thymoma-associated exfoliative dermatitis in a cat treated with ciclosporin A.

JFMS Open Rep 2020 Jan-Jun;6(1):2055116920902307. Epub 2020 Feb 11.

Department of Clinical Sciences, Université de Toulouse, ENVT, Toulouse, France; UDEAR, Université de Toulouse, INSERM, ENVT, Toulouse, France.

Case Summary: A 6-year-old neutered female European Shorthair cat was referred for chronic, moderately pruritic, alopecic and exfoliative dermatosis that was unresponsive to antiparasitic, antibiotic or steroidal anti-inflammatory drugs. The cat presented with truncular alopecia and numerous whitish adherent scales covering the whole body. Differential diagnoses included sebaceous adenitis, dermatophytosis, demodicosis, exfoliative dermatitis associated or not with thymoma, drug reaction, feline immunodeficiency virus- or feline leukaemia virus-associated dermatoses, epitheliotropic T-cell lymphoma, and yeasts and/or bacterial overgrowth. Read More

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February 2020

Molecular epidemiology, susceptibility and exoenzyme screening of clinical isolates.

J Med Microbiol 2020 Mar;69(3):436-442

Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China.

folliculitis (MF) and pityriasis versicolor (PV) are common dermatoses caused by species. Their molecular epidemiology, drug susceptibility and exoenzymes are rarely reported in China. To investigate the molecular epidemiology, drug susceptibility and enzymatic profile of clinical isolates. Read More

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Malassezia (Pityrosporum) Folliculitis Incognito: Malessezia-associated Folliculitis Masked by Topical Corticosteroid Therapy.

Cureus 2020 Jan 1;12(1):e6531. Epub 2020 Jan 1.

Dermatology/Dermatopathology, Compass Dermatopathology, Inc., San Diego, USA.

Malassezia (Pityrosporum) folliculitis usually appears as pruritic monomorphous papules and pustules on the upper back, chest, extensor arms and face. Acne vulgaris, bacterial folliculitis, eosinophilic folliculitis and systemic corticosteroid-induced acne can clinically mimic the fungal-caused acneiform condition. The designation incognito is used to describe tinea or scabies when the characteristic presentation is masqueraded by the application of topical corticosteroid treatment. Read More

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January 2020

Critical synthesis of available data in Malassezia folliculitis and a systematic review of treatments.

J Eur Acad Dermatol Venereol 2020 Aug 30;34(8):1672-1683. Epub 2020 Apr 30.

Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.

Folliculitis is an inflammatory process involving the hair follicle, frequently attributed to infectious causes. Malassezia, an established symbiotic yeast that can evolve to a skin pathogen with opportunistic attributes, is a common source of folliculitis, especially when intrinsic (e.g. Read More

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