41 results match your criteria Majocchi Granuloma


Majocchi's granuloma: Autoinoculation and adaption of Trichophyton rubrum with molecular evidence.

Mycoses 2021 Oct 16;64(10):1272-1278. Epub 2021 Jul 16.

Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China.

Background: Trichophyton rubrum, an important aetiological agent of superficial dermatophytosis, occasionally penetrates into deeper tissues, causing inflammation and a granulomatous response. Only few case reports of T. rubrum granuloma with molecular evidence for autoinoculation have been published. Read More

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October 2021

ALA-PDT successfully treated Majocchi's granuloma by directly killing Trichophyton tonsurans and recruiting T lymphocytes.

Photodiagnosis Photodyn Ther 2021 Sep 15;35:102328. Epub 2021 May 15.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Baode Road 1278, Shanghai, 200443, China. Electronic address:

Background: Majocchi's granuloma (MG) is a deep persistent suppurative granulomatous perifolliculitis which might be caused by Trichophyton tonsurans (T. tonsurans). Conventional treatment for MG is oral administration of systematic antifungal drugs, associated with a low cure rate and a high relapse rate. Read More

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September 2021

Vulvar Majocchi granuloma and kerion formation in an immunocompetent female.

Dermatol Online J 2019 Sep 15;25(9). Epub 2019 Sep 15.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL.

We report a rare case of vulvar Majocchi granuloma and kerion formation secondary to Trichophyton in an immunocompetent woman. The patient responded well to oral terbinafine and a short course of oral corticosteroids with a slow taper. Resolution of deep dermatophytosis requires prompt pathogen identification and treatment to avoid scarring and hair loss. Read More

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September 2019

Possible rabbit breeders' infection characterized by Majocchi's granuloma in immunocompetent host: Case report.

Med Mycol Case Rep 2019 Dec 21;26:19-22. Epub 2019 Sep 21.

Department of Dermatology, The Affiliated Hospital, Guizhou Medical University, Guiyang, China.

We report on a family of three in a rabbit farm, especially children with Majocchi granuloma as the main clinical feature of cross-infection of , provides experience in reducing the rate of clinical misdiagnosis. Based on the pathological features of Majocchi's granuloma, taking into account that severe inflammatory reactions are also responsible for the damage of the body. In Majocchi's granuloma treatment strategy, we recommend the use of anti-inflammatory Chinese medicines that have a hormonal effect and have no side effects. Read More

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December 2019

Two Rare Cases of Tinea Corporis Caused by Trichophyton verrucosum and Trichophyton interdigitale in a Teenage Girl.

Cureus 2019 Aug 5;11(8):e5325. Epub 2019 Aug 5.

Dermatology, University of Texas Medical Branch, Galveston, USA.

We present two cases of tinea corporis caused by  and  in a teenage girl who works with farm animals. We describe the differences in presentation between zoophilic dermatophytes and anthropophilic dermatophytes. Also, we report some of the typical features of the two rare species,  and . Read More

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Treatment of Majocchi granuloma. A retrospective study of 36 cases.

J Dermatolog Treat 2021 03 12;32(2):264-265. Epub 2019 Aug 12.

Dermatology Service, Mycology Department, Hospital General de México, "Dr. Eduardo Liceaga", Mexico, Mexico.

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Changing Concepts and Current Definition of Majocchi's Granuloma.

Mycopathologia 2020 Feb 11;185(1):187-192. Epub 2019 Jul 11.

Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.

Dermatophytic granuloma characterized by perifollicular granulomatous inflammation was first described by Domenico Majocchi and was later named after him, Majocchi's granuloma (MG). Although the initial description was related to a dermatophyte Trichophyton tonsurans, later reports linked MG to non-dermatophytes (Phoma, Aspergillus, Malbranchea), which led to a confusion of disease patterns caused by cutaneous pathogens and general opportunistic microorganisms. Furthermore, several causative agents of MG described in the literature were not confirmed as such. Read More

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February 2020

Majocchi granuloma on a child's face.

Dermatol Online J 2018 Dec 15;24(12). Epub 2018 Dec 15.

Department of Pediatrics, Division of Pediatric Dermatology, Federal University of Paraná Hospital de Clínicas da UFPR, Curitiba, Paraná.

Majocchi granuloma (MG) is a rare dermal and subcutaneous fungal infection. We report a rare case of MG on the face of a six-year-old child caused by Trichophyton mentagrophytes after long term use of topical corticosteroids and other inadequate topical medications. He was treated with griseofulvin 25 mg/kg/day for 35 days unsuccessfully and successful treatment was obtained with terbinafine. Read More

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December 2018

[Majocchi granuloma].

An Pediatr (Engl Ed) 2019 Oct 13;91(4):274-275. Epub 2018 Sep 13.

Servicio de Pediatría, Hospital Universitario Francesc de Borja, Gandía, Valencia, España. Electronic address:

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October 2019

[Mexican case of tinea incognito and granuloma de Majocchi acquired from a hedgehog].

Rev Chilena Infectol 2018 04;35(2):204-206

Sección de Micología, Hospital General Dr. Manuel Gea. González, Ciudad de México, México.

Exotic pets, such as the ground hedgehog, are capable of transmitting to the human being different zoonoses, such as salmonellosis, mycobacteria, protozoa such as Cryptosporidium parvum, and dermatophytosis. We present the case report of a male adult patient, who had recently acquired a ground hedgehog, who presented in his hand a ringworm lesion incognito and a Majocchi granuloma. The etiological agent was identified as Trichophyton erinacei by mycological culture and molecular biology. Read More

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Majocchi's granuloma (granuloma trichophyticum) in a guinea pig owner: A case report and literature review.

J Mycol Med 2018 Sep 1;28(3):523-526. Epub 2018 Jun 1.

Department and Clinic of Dermatology, Karol Marcinkowski University of Medical Sciences, Poznan, Poland; Department of Medical Mycology and Dermatology, Poznan University of Medical Sciences, Poznan, Poland.

Majocchi's granuloma is a folliculitis caused by dermatophytes, which is most commonly located on the skin of the lower limbs in women. A favorable factor for the infection is an injury caused by epilation, which, together with an existing fungal infection, can lead to the spread of folliculitis to other parts of the body. The disease is extremely rare (Burgdorf et al. Read More

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September 2018

Majocchi granuloma presenting as a verrucous nodule of the lip.

Proc (Bayl Univ Med Cent) 2018 Jan 10;31(1):115-116. Epub 2018 Jan 10.

Center for Clinical Studies, Houston, Texas.

We present a case of Majocchi granuloma, a deep folliculitis, on the lip of a healthy 41-year-old man. The patient was successfully treated with systemic and topical antifungal medications. Correct diagnosis of this rare condition is needed, since misdiagnosis as an inflammatory dermatitis and treatment using topical corticosteroids can lead to dissemination of the infection. Read More

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January 2018

A 61-year-old man with erythematous forearm papules three months after liver transplantation.

Transpl Infect Dis 2018 Jun 25;20(3):e12869. Epub 2018 Mar 25.

Division of Infectious Diseases, The University of North Carolina, Chapel Hill, NC, USA.

A 61-year-old Caucasian man presented with papules on his left forearm and hand three months after liver transplantation: images from physical exam, pathology, and microbiology are presented. Skin biopsy confirmed the presence of fungal elements within the hair shaft, which is consistent with Majocchi granuloma, also known as nodular granulomatous perifolliculitis. A combination of fungal culture, microscopic morphology, and gene sequencing was used to identify the causative organism. Read More

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Majocchi granuloma in a 58-year-old man with treatment-resistant annular scaling plaque.

CMAJ 2017 Dec;189(48):E1493

Departments of Pathology (Roy) and Dermatology (Davar), Centre Hospitalier de L'Université de Montréal, Montréal, Que.

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December 2017

Severe dermatophytosis in solid organ transplant recipients: A French retrospective series and literature review.

Transpl Infect Dis 2018 Feb 25;20(1). Epub 2018 Jan 25.

Infectious Diseases and Tropical Medicine Department, Necker-Pasteur Infectious Diseases Center, Necker-Enfants malades Hospital, AP-HP, IHU Imagine, Paris Descartes University, Paris, France.

Objective: Severe dermatophytosis is described in immunocompromised patients with defective cellular immunity. We report here a large series and a literature review of severe dermatophytosis in solid-organ transplant (SOT) recipients.

Method: The data main source was a national French retrospective study of severe dermatophytosis in SOT recipients between 2010 and 2016. Read More

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February 2018

The influence of immune status, age, and sex on Majocchi granuloma: a review of 52 cases from a tertiary level hospital and published Korean cases in literature.

Int J Dermatol 2017 Nov 20;56(11):1139-1145. Epub 2017 Sep 20.

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

Background: Majocchi granuloma (MG) is a rare dermal and subcutaneous granulomatous inflammation caused by dermatophytes. The detailed characteristics of MG are not fully elucidated. This study investigated the influence of systemic immune status, age, and sex on the clinical, demographic, mycological, and therapeutic characteristics of MG in Korea. Read More

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November 2017

A severe transmissible Majocchi's granuloma in an immunocompetent returned traveler.

Med Mycol Case Rep 2017 Dec 6;18:5-7. Epub 2017 Jul 6.

Public Health Microbiology Forensic and Scientific Services, Health Support Queensland, Australia.

Severe dermatophyte infection is rare in immunocompetent adults. Recently cases have been described in travelers returning from South East Asia (Luchsinger et al., 2015) [1]. Read More

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December 2017

Exfoliative erythroderma and palmoplantar hyperkeratosis associated with Majocchi's granuloma by Trichophyton tonsurans in a patient with AIDS.

Rev Iberoam Micol 2017 Jul - Sep;34(3):185-188. Epub 2017 Apr 25.

Dermatology, Hospital Geral Policlínica do Rio de Janeiro and Instituto Nacional de Infectologia (INI) Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil.

Background: Dermatophytoses are skin superficial mycoses in which clinical manifestations are directly related to the virulence of the infecting microorganism or the host immunity.

Case Report: We describe a severe case of dermatophytosis associated with exfoliative erythroderma, substantial palmoplantar keratoderma, onychodystrophy affecting all nails, diffuse non-scarring alopecia and tissue fungal invasion by Trichophyton tonsurans, which led us to the diagnosis of AIDS. Direct examination and culture for fungi from skin scraping from two different sites were performed. Read More

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Pubic Majocchi's Granuloma Unresponsive to Itraconazole Successfully Treated with Oral Terbinafine.

Skin Appendage Disord 2016 Feb 3;1(3):111-3. Epub 2015 Sep 3.

Second Department of Dermatology and Venereology, 'Attikon' General University Hospital, Athens, Greece.

Majocchi's granuloma (MG) is an uncommon deep fungal infection. It is usually caused by Trichophyton rubrum and may develop in any hair-bearing skin, commonly on the face and the extremities. We present a 27-year-old female with MG of the pubic area treated unsuccessfully with itraconazole capsule 100 mg for 4 weeks. Read More

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February 2016

Majocchi Granuloma of the Breast: A Rare Clinical Entity.

Actas Dermosifiliogr 2016 Sep 28;107(7):610-2. Epub 2016 Mar 28.

Department of Dermatology, ESIPGIMSR Basaidarapur, New Delhi, 15, India.

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September 2016

Majocchis Granuloma Caused by Trichophyton mentagrophytes in 2 Immunocompetent Patients.

Actas Dermosifiliogr 2017 Jan - Feb;108(1):e6-e8. Epub 2016 Mar 4.

Department of Dermatology at Karolinska University Hospital, Stockholm, Sweden.

Majocchi granuloma is an uncommon deep follicular inflammation caused by dermatophytes and affects immunocompetent and immunocompromised patients. The clinical findings overlap with other skin conditions such bacterial infections and inflammatory skin diseases, thereby delaying correct diagnosis. We describe 2 cases in immunocompetent patients. Read More

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November 2017

[Majocchi granuloma. Presentation of a case in Primary Care].

Semergen 2016 Nov - Dec;42(8):599-600. Epub 2015 Dec 3.

Centro de Salud Reyes Magos, Servicio Madrileño de Salud, Área Este, Madrid, España.

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Tinea profunda of the genital area. Successful treatment of a rare skin disease.

Dermatol Ther 2016 May 2;29(3):181-3. Epub 2015 Nov 2.

University of Rome "G. Marconi", Rome, Italy.

We present a rare case of 36-year-old female patient, who developed a severe Majocchi granuloma in the pubis after waxing, with isolated causative agent Trichophyton mentagrophytes. The condition was initially misdiagnosed as a bacterial folliculitis and treated unsuccessfully with topical corticosteroids and antibiotics. After the adequate diagnose was confirmed by mycological examination, followed by histopathological verification, complete remission of the symptoms was achieved at the 4th week after initiating 6 weeks course of antifungal therapy with Terbinafine 250 mg/daily dose, while good therapeutic response was observed even in the 10th day. Read More

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Majocchi granuloma in a pregnant woman.

Obstet Gynecol 2014 Aug;124(2 Pt 2 Suppl 1):423-425

Departments of Dermatology, the First People's Hospital of Shunde, Foshan, and Zhujiang Hospital, Guangzhou, China.

Background: Majocchi granuloma is a cutaneous dermatophyte infection of the dermal and subcutaneous tissues characterized by chronic erythematous and indurated plaques, which are almost always the result of immunodeficiency and trauma.

Case: Disseminated dermatophyte Majocchi granuloma was diagnosed in a 19-year-old woman at 32 weeks of gestation and had no history of trauma or chronic illness. She was treated with topical antifungal medications until delivery, at which time systemic medications were started. Read More

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[Majocchi granuloma. Advantages of optical brightener staining in a case report].

Authors:
P A Mayser

Hautarzt 2014 Aug;65(8):721-4

Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gaffkystr. 14, 35385, Gießen, Deutschland,

A patient presented with Majocchi granuloma caused by T. rubrum. By the use of optical brighteners, fungal elements in the deep dermis could be detected more sensitive than with PAS staining. Read More

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Mycobacteria infection in an immunocompetent patient with no risk factors: evaluation and management of non-healing majocchi granuloma-type nodule.

Dermatol Online J 2013 Aug 15;19(8):19260. Epub 2013 Aug 15.

SUNY Downstate.

Atypical mycobacterial infections are more commonly described among immunocompromised patients, although there has been an increasing incidence in recent years of infections in immunocompetent hosts. Normally preceding trauma is a risk factor for infection. We describe a case of Mycobacteria chelonae infection in a healthy individual with no risk factors. Read More

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Trichophyton rubrum-induced Majocchi's Granuloma in a heart transplant recipient. A therapeutic challenge.

J Dermatol Case Rep 2012 Sep;6(3):70-2

Department of Dermatology, University Hospital, Zürich, Switzerland.

Background: Solid organ transplant recipients are at an increased risk for infections because of long-term immunosuppression to prevent graft rejection. Fungal infections with dermatophytes are a common cause of cutaneous infections seen in organ transplant recipients and cutaneous dermatophyte infections may progress to Majocchi's granuloma. Itraconazole is an anti-fungal compound used for the treatment of infections of the skin, nails and mucous membranes. Read More

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September 2012

Tinea corporis gladiatorum presenting as a majocchi granuloma.

ISRN Dermatol 2011 12;2011:767589. Epub 2011 Apr 12.

Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4L8.

Background. Wrestlers are at increased risk of developing cutaneous infections, including fungal infections caused by dermatophytes. Erythematous lesions due to tinea infections can be mistakenly diagnosed as an inflammatory dermatitis and incorrectly treated with potent topical corticosteroid treatments which cause localized skin immunosuppression. Read More

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