799,869 results match your criteria Magnetic Resonance Materials in Physics Biology and Medicine[Journal]


In situ soft x-ray absorption spectroscopic study of polycrystalline Fe/MgO interfaces.

J Phys Condens Matter 2018 Dec 17. Epub 2018 Dec 17.

Center for Spintronic Materials, Amity University, Sector 125, Noida, INDIA.

Interfacial interactions between a layer of iron and MgO hold the key to various phenomena like, tunnel magnetoresistance, perpendicular magnetic anisotropy, interlayer exchange coupling, observed in the system. Interface structure has been studied<i> in situ </i>during deposition of iron on MgO surface, using soft x-ray absorption spectroscopy (SXAS). Sub-monolayer sensitivity of SXAS, combined with <i>in situ</i> measurements as a function of iron layer thickness, allowed one to study the evolution of interface with film thickness. Read More

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December 2018

Competitive removal of Pb and malachite green from water by magnetic phosphate nanocomposites.

Water Res 2018 Nov 28;150:442-451. Epub 2018 Nov 28.

College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, China.

The competitive removal of Pb and malachite green (MG) from water by three magnetic phosphate nanocomposites (FeO/Ba(PO), FeO/Sr(PO)(OH), and FeO/SrBa(PO)(OH), namely "FBP", "FSP", and "FSBP", respectively) was systematically investigated compared with FeO ("F") nanoparticle. Temperature and adsorbent dosage for competitive removal were optimized to be 20 °C and 0.05 g in 50 mL. Read More

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November 2018

Validation of the Hepatocellular Carcinoma Early detection Screening (HES) algorithm in a Cohort of Veterans with Cirrhosis.

Clin Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.

Houston VA Health Services Research and Development Service Center of Excellence (Houston, TX), Section of Health Services Research, Michael E. DeBakey VA Medical Center (Houston, TX) and Baylor College of Medicine, Houston, TX. Electronic address:

Background & Aims: Early detection of hepatocellular carcinoma (HCC) through surveillance reduces mortality associated with this cancer. Guidelines recommend HCC surveillance every 6 months for patients with cirrhosis, via ultrasonography, with or without measurement of serum level of alpha fetoprotein (AFP).

Methods: We previously developed and internally validated an HCC early detection screening (HES) algorithm that included patient's current level of AFP, rate of AFP change, age, level of alanine aminotransferase, and platelet count in a department of Veterans affairs (VA) cohort with active hepatitis C virus-related cirrhosis. Read More

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December 2018

Distribution of endocrine-disrupting chemicals in colloidal and soluble phases in municipal secondary effluents and their removal by different advanced treatment processes.

Chemosphere 2018 Dec 4;219:730-739. Epub 2018 Dec 4.

State Key Laboratory of Pollution Control and Resource Reuse, Center for Hydrosciences Research, School of the Environment, Nanjing University, Nanjing, PR China.

In this work, the partition of endocrine-disrupting chemicals (EDCs) in colloid-bound and truly dissolved phases in municipal wastewater before and after advanced treatment processes was determined. The effluents, which were filtered using a 0.45 μm membrane, were further separated with the 1 kDa cross-flow ultrafiltration system into two phases, namely, colloidal phase (0. Read More

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December 2018

Increased activation in the left ventrolateral prefrontal cortex and temporal pole during tonality change in music.

Neurosci Lett 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address:

In human music, the tonality (key) may change to punctuate sectional structures and to produce emotional effects. A tonality change would sound "smoother" when it is supported by appropriate harmony. This functional magnetic resonance imaging study examined the neural substrates of the processing of tonality change. Read More

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December 2018

Combination of free-breathing radial 3D fat-suppressed T1-weighted gradient-echo sequence with diffusion weighted images: Potential for differentiating malignant from benign peripheral solid pulmonary masses.

Magn Reson Imaging 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiology, The affiliated hospital of Shaanxi university of Chinese medicine, Xian Yang, China. Electronic address:

Objectives: High resolution CT is the most commonly used radiological method for differentiating benign from malignant peripheral solid pulmonary masses, however, some of them are not easily diagnosed by morphology alone. Furthermore, due to the radiation dose, it is unsuitable for patients with disorders requiring repeated examinations over prolonged periods. The aims of this study were to evaluate whether a combination of diffusion-weighted images (DWI) and free-breathing radial 3D fat-suppressed T1-weighted gradient echo (radial volumetric interpolated breath-hold examination, radial VIBE) sequence can enable discrimination between benign from malignant peripheral solid pulmonary masses. Read More

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December 2018

Molecular Tunability of Magnetic Exchange Bias and Asymmetrical Magnetotransport in Metalloporphyrin/Co Hybrid Bilayers.

ACS Nano 2018 Dec 17. Epub 2018 Dec 17.

Molecular spins as individual are promising quantum states for emerging computation technologies. The "on surface" configuration of molecules in proximity to a magnetic film allows control over the orientations of molecular spins and coupling between them. The stacking of planar molecular spins could favor antiferromagnetic interlayer couplings and lead to pinning of the magnetic underlayer via the exchange bias, which is extensively utilized in ultrafast and high-density spintronics. Read More

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December 2018

Eosinophilic cerebrospinal fluid pleocytosis associated with neural Angiostrongylus vasorum infection in a dog.

Vet Clin Pathol 2018 Dec 17. Epub 2018 Dec 17.

Department of Small Animal Clinical Science, Institute of Veterinary Science, University of Liverpool, Neston, UK.

A 1-year-old, female intact Pug dog was presented to the Small Animal Teaching Hospital of the University of Liverpool with a 4-week history of progressive multifocal intracranial signs. Magnetic resonance imaging (MRI) detected multiple hemorrhagic lesions in the brain. The Baermann and zinc sulfate flotation tests with centrifugation, performed on fecal samples, were positive for lungworm larvae and an antigenic test confirmed Angiostrongylus vasorum infection. Read More

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December 2018

Bayesian inference of protein conformational ensembles from limited structural data.

PLoS Comput Biol 2018 Dec 17;14(12):e1006641. Epub 2018 Dec 17.

Biochemistry and Structural Biology, University of Lund, Lund, Sweden.

Many proteins consist of folded domains connected by regions with higher flexibility. The details of the resulting conformational ensemble play a central role in controlling interactions between domains and with binding partners. Small-Angle Scattering (SAS) is well-suited to study the conformational states adopted by proteins in solution. Read More

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December 2018

Intracranial Hemorrhage in Children With Inherited Bleeding Disorders: A Single Center Study in China.

J Pediatr Hematol Oncol 2018 Dec 14. Epub 2018 Dec 14.

Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Intracranial hemorrhage (ICH) is a life-threatening condition in children. Inherited bleeding disorders (IBD) have high risk of ICH.

Aim: This single center study aims to identify the incidence, risk factors, and neurological outcome of ICH in children who suffer from IBD. Read More

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December 2018

Improvement in Functional Outcome Scores Despite Persistent Pain With 1 Year of Nonsurgical Management for Acetabular Labral Tears With or Without Femoroacetabular Impingement.

Am J Sports Med 2018 Dec 17:363546518814484. Epub 2018 Dec 17.

Department of Orthopaedic Surgery, Mass General Hospital, Boston, Massachusetts, USA.

Background:: Acetabular labral tears are increasingly recognized as a source of hip pain in a younger active population. Given the significant focus on surgical intervention, there has been limited investigation on the nonsurgical management and natural history of such injuries.

Hypothesis:: Patients undergoing nonsurgical treatment for symptomatic acetabular labral tears experience functional improvement based on patient-reported outcome measures over the course of 1 year. Read More

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December 2018

High-Pressure Synthesis of LuNiIrO with Ferrimagnetism and Large Coercivity.

Inorg Chem 2018 Dec 17. Epub 2018 Dec 17.

Department of Chemistry and Chemical Biology , Rutgers, The State University of New Jersey , 610 Taylor Road , Piscataway , New Jersey 08854 , United States.

Double-perovskite LuNiIrO was synthesized at high pressure (6 GPa) and high temperature (1300 °C). Synchrotron powder X-ray diffraction indicates that its structure is a monoclinic double perovskite (space group P2/ n) with a small, 11% Ni/Ir antisite disorder. X-ray absorption near-edge spectroscopy measurements established Ni and Ir formal oxidation states. Read More

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December 2018

Facile and Massive Aluminothermic Synthesis of Mayenite Electrides from Cost-Effective Oxide and Metal Precursors.

Inorg Chem 2018 Dec 17. Epub 2018 Dec 17.

Department of Materials Science and Engineering , Clemson University , Clemson , South Carolina 29634 , United States.

Subnanoporous mayenite electride [CaAlO](O)(e) (C12A7:e) as the first room temperature-stable inorganic electride has attracted intensive attention because of its fascinating chemical, electrical, optical, and magnetic properties. However, it usually needs to be synthesized through a complicated multistep process involving high temperature (e.g. Read More

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December 2018

Anomalous Stoichiometry, 3-D Bridged Triangular/pentagonal Layered Structured Artificial Antiferromagnet for the Prussian Blue Analog A3MnII5(CN)13 (A = NMe4, NEtMe3). A Cation Adaptive Structure.

J Am Chem Soc 2018 Dec 17. Epub 2018 Dec 17.

The shape of the organic cation dictates both the composition and the extended 3-D structure for hybrid organic/inorganic Prussian blue analogs (PBAs) of AaMnIIb(CN)a+2b (A = cation) stoichiometry. Alkali PBAs are typically cubic with both MC6 and M'N6 octahedral coordination sites, and the alkali cation content depends on the M and M' oxidation states. The reaction of MnII(O2CCH3)2 and A+CN- (A = NMe4, NEtMe3) forms a hydrated material of A3MnII5(CN)13 composition. Read More

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December 2018
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Clinical findings and outcome of dogs with unilateral masticatory muscle atrophy.

J Vet Intern Med 2018 Dec 17. Epub 2018 Dec 17.

Department of Veterinary Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, England, United Kingdom.

Background: Little is known about the spectrum of underlying disorders in dogs with unilateral masticatory muscle (MM) atrophy.

Objectives: To evaluate the clinical presentation, magnetic resonance imaging (MRI) findings, and outcome of dogs with unilateral MM atrophy.

Animals: Sixty-three client-owned dogs. Read More

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December 2018

Practical Application of H Benchtop NMR Spectroscopy for the Characterization of a Non-Aqueous Phase Liquid from a Contaminated Environment.

Magn Reson Chem 2018 Dec 17. Epub 2018 Dec 17.

School of Environmental Sciences, University of Guelph, Guelph, On, Canada, N1G 2W1.

Non-Aqueous Phase Liquids (NAPLs) located at the surface of the water table and/or below the water table are often a significant source for groundwater contamination near current or former commercial/industrial facilities. Due to the complex and long history of many industrial sites, these NAPLs often contain a complex mixture of contaminants and as such can be difficult to fully characterize using conventional analytical methods. Remediation and risk assessment activities at sites containing NAPLs may, subsequently, be hindered as the contamination profile may not be fully understood. Read More

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December 2018

Diagnostic Errors in Initial Misdiagnosis of Optic Nerve Sheath Meningiomas.

JAMA Neurol 2018 Dec 17. Epub 2018 Dec 17.

Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.

Importance: Diagnostic errors can lead to the initial misdiagnosis of optic nerve sheath meningiomas (ONSM), which can lead to vision loss.

Objective: To identify factors contributing to the initial misdiagnosis of ONSM.

Design, Setting, And Participants: We retrospectively reviewed 35 of 39 patients with unilateral ONSM (89. Read More

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December 2018
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Gender-related differences in cue-elicited cravings in Internet gaming disorder: The effects of deprivation.

J Behav Addict 2018 Dec 17:1-12. Epub 2018 Dec 17.

5 Department of Psychiatry and Neurobiology, Child Study Center, Yale University School of Medicine , New Haven, CT, USA.

Background: Online gaming has become a popular leisure activity, in which males more frequently develop Internet gaming disorder (IGD) compared to females. However, gender-related neurocognitive differences have largely not been systematically investigated in IGD.

Methods: Cue-elicited-craving tasks were performed before game playing and immediately after deprivation operationalized as a forced break from gaming when the Internet was disconnected. Read More

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December 2018

Short-Term Outcomes Predict Long-Term Satisfaction in Patients Undergoing Laparoscopic Magnetic Sphincter Augmentation.

J Laparoendosc Adv Surg Tech A 2018 Dec 15. Epub 2018 Dec 15.

1 Department of Surgery, Mayo Clinic in Florida , Jacksonville, Florida.

Introduction: Laparoscopic magnetic sphincter augmentation (MSA) has been shown to be efficacious therapy for gastroesophageal reflux disease (GERD) refractory to maximal medical management. Herein, we present our experience with this procedure and an analysis of our outcomes.

Materials And Methods: Medical records were retrospectively reviewed of 98 patients who underwent laparoscopic MSA for GERD at a single institution from 2012 to 2016. Read More

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December 2018

Proteomics in the Diagnosis of Endometriosis: Opportunities and Challenges.

Authors:
Simone Ferrero

Proteomics Clin Appl 2018 Dec 17:e1800183. Epub 2018 Dec 17.

Prof. S. Ferrero, Prof. S. Ferrero Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.

The non-surgical diagnosis of endometriosis is still challenging for the clinician. Ultrasonography and magnetic resonance imaging can be used to diagnose ovarian endometriotic cysts and deep infiltrating endometriosis; but their performance is poor in the diagnosis of initial stages of endometriosis. CA-125 and other serum markers (such as CA 19-9, serum protein PP14, interleukins and angiogenetic factors) have been measured in women with endometriosis but they are not reliable for the diagnosis of the disease. Read More

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December 2018

Quantitative susceptibility mapping detects neovascularization of the epiphyseal cartilage after ischemic injury in a piglet model of legg-calvé-perthes disease.

J Magn Reson Imaging 2018 Dec 17. Epub 2018 Dec 17.

Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.

Background: Legg-Calvé-Perthes disease (LCPD) is a childhood hip disorder thought to be caused by disruption of blood supply to the developing femoral head. There is potential for imaging to help assess revascularization of the femoral head.

Purpose: To investigate whether quantitative susceptibility mapping (QSM) can detect neovascularization in the epiphyseal cartilage following ischemic injury to the developing femoral head. Read More

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December 2018
1 Read

Heterologous biosynthesis of a fungal macrocyclic polylactone requires only two iterative polyketide synthases.

Org Biomol Chem 2018 Dec 17. Epub 2018 Dec 17.

Department of Chemistry, Special Research Unit for Advanced Magnetic Resonance and Center of Excellence for Innovation in Chemistry, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand.

Menisporopsin A is a bioactive macrocyclic polylactone produced by the fungus Menisporopsis theobromae BCC 4162. A scheme for the biosynthesis of this compound has been proposed, in which reducing (R) and non-reducing (NR) polyketide synthases (PKSs) would catalyze the formation of each menisporopsin A subunit, while an additional non-ribosomal peptide synthetase (NRPS)-like enzyme would be required to perform multiple esterification and cyclolactonization reactions. Transcriptome analysis of M. Read More

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December 2018

Patents on quantitative susceptibility mapping (QSM) of tissue magnetism.

Recent Pat Biotechnol 2018 Dec 16. Epub 2018 Dec 16.

Department of Radiology, Weill Medical College of Cornell University, New York. United States.

Background: Quantitative susceptibility mapping (QSM) depicts biodistributions of tissue magnetic susceptibility sources, including endogenous iron and calcifications, as well as exogenous paramagnetic contrast agents and probes. When comparing QSM with simple susceptibility weighted MRI, QSM eliminates blooming artifacts and shows reproducible tissue susceptibility maps independent of field strength and scanner manufacturer over a broad range of image acquisition parameters. For patient care, QSM promises to inform diagnosis, guide surgery, gauge medication, and monitor drug delivery. Read More

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December 2018

Clinical Features and Endolymphatic Hydrops in Patients With MRI Evidence of Hydrops.

Ann Otol Rhinol Laryngol 2018 Dec 17:3489418819551. Epub 2018 Dec 17.

1 ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.

Objectives:: The purpose of this study was to investigate the correlation between grades of endolymphatic hydrops (ELH) and clinical characteristics and determine the detailed clinical characteristics of Ménière's disease (MD) patients with evidence of hydrops based on magnetic resonance imaging (MRI).

Methods:: One hundred ninety-eight MD patients (396 ears) with MRI evidence of hydrops were included. ELH grades were evaluated using the Nakashima grading standard. Read More

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December 2018

A preliminary comparison of masticatory performances between immediately loaded and conventionally loaded mandibular two-implant overdentures with magnetic attachments.

Clin Implant Dent Relat Res 2018 Dec 17. Epub 2018 Dec 17.

Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Background: Two-implant overdentures (2-IODs) is an expected treatment option to improve the masticatory performance (MP) of edentulous individuals.

Purpose: The purpose of the current study was to compare MPs between immediately loaded and conventionally loaded mandibular 2-IODs retained by magnet attachments.

Materials And Methods: Nineteen participants with edentulous mandibles were randomly assigned to an immediately loaded group or a conventionally loaded group. Read More

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December 2018

Pre-procedural imaging to guide transcoronary ethanol ablation for refractory septal ventricular tachycardia.

J Cardiovasc Electrophysiol 2018 Dec 16. Epub 2018 Dec 16.

Arrhythmia Unit. Cardiology Service. Hospital Universitari Vall d'Hebron.

Background: Radiofrequency ablation (RF) of ventricular tachycardia (VT) due to intramural foci has a high recurrence rate. Several techniques as bipolar ablation, irrigated needle ablation catheter and retrograde coronary venous ethanol ablation have been suggested. Transarterial coronary ethanol ablation (TCEA) can be also effective. Read More

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December 2018

Ambient Degradation-Induced Spin Paramagnetism in Phosphorene.

Small 2018 Dec 17:e1804386. Epub 2018 Dec 17.

National Laboratory of Solid State Microstructures, Collaborative Innovation Center of Advanced Microstructures, Jiangsu Provincial Key Laboratory for Nanotechnology, Nanjing University, Nanjing, 210093, P. R. China.

The sizeable direct bandgap, high mobility, and long spin lifetimes at room temperature offer black phosphorus (BP) potential applications in spin-based semiconductor devices. Toward these applications, a critical step is creating a magnetic response in BP, which is arousing much interest. It is reported here that ambient degradation of BP, which is immediate and inevitable and greatly changes the semiconducting properties, creates magnetic moments, and any degree of degradation leads to notable paramagnetism. Read More

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December 2018

Peripheral nervous system involvement in lymphomas.

J Peripher Nerv Syst 2018 Dec 16. Epub 2018 Dec 16.

Hematology and Clinical Immunology Unit, Department of Medicine, University of Padova, Padova.

The peripheral nervous system may be involved at any stage in the course of lymphoproliferative diseases. The different underlying mechanisms include neurotoxicity secondary to chemotherapy, direct nerve infiltration (neurolymphomatosis), infections, immune-mediated, paraneoplastic or metabolic processes and nutritional deficiencies. Accordingly, the clinical features are heterogeneous and depend on the localization of the damage (ganglia, roots, plexi, peripheral nerves) and on the involved structures (myelin, axon, cell body). Read More

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December 2018
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Diffusion tensor imaging as an adjunct tool for the diagnosis of varicocele.

Andrologia 2018 Dec 16:e13210. Epub 2018 Dec 16.

Department of Clinical Radiology, Medical School, University of Ioannina, Ioannina, Greece.

A noninvasive imaging technique providing information about testicular dysfunction in testes with varicocele would be useful. The aim is to measure the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in testes of infertile men with varicocele and to assess interobserver agreement. Sixteen infertile men with varicocele and 14 age-matched controls underwent 1. Read More

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December 2018

Auditory and speech function after cochlear implantation in prelingually deaf children with white matter lesions.

Dev Med Child Neurol 2018 Dec 16. Epub 2018 Dec 16.

Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Aim: To explore how auditory and speech function developed post-cochlear implantation (pCI) in prelingually deaf children with white matter lesions (WML).

Method: Patients (41 males, 29 females; mean age at implantation 2y 11mo [SD 7.5mo], range 1y 8mo-5y) were divided into the following groups according to preoperative brain magnetic resonance imaging evaluation: mild WML, moderate WML, severe WML, and control. Read More

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December 2018

Association between late gadolinium enhancement and global longitudinal strain in patients with rheumatic mitral stenosis.

Int J Cardiovasc Imaging 2018 Dec 17. Epub 2018 Dec 17.

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia / National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.

The correlation between the extent of myocardial fibrosis and subclinical left ventricle (LV) systolic dysfunction in rheumatic mitral stenosis (MS) has not been widely studied. We sought to evaluate the correlation between the extent of LV myocardial fibrosis quantified by late gadolinium enhancement (LGE) using cardiac magnetic resonance (CMR) and global longitudinal strain (GLS) by speckle tracking echocardiography (STE) in patients with rheumatic MS. We prospectively evaluated 36 consecutive rheumatic MS patients who were planning to undergo mitral valve surgery. Read More

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December 2018

Aberrant white matter properties of the callosal tracts implicated in girls with attention-deficit/hyperactivity disorder.

Brain Imaging Behav 2018 Dec 17. Epub 2018 Dec 17.

Huaxi Magnetic Resonance Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, China.

Aberrant microstructure of the callosal tracts has been found in boys with attention-deficit/hyperactivity disorder (ADHD). However, it is unclear whether the previously identified white matter (WM) alterations in boys with ADHD are also present in girls with ADHD. Thus, we applied diffusion tensor imaging (DTI) to investigate WM alterations in the callosal tracts in girls with ADHD. Read More

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December 2018

Spectroscopic and magnetic investigations of a spin-frustrated Mn-doped CoAlO spinel.

Phys Chem Chem Phys 2018 Dec 17. Epub 2018 Dec 17.

School of Materials Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.

Single-phase polycrystalline spin-frustrated spinel oxides Co1-xMnxAl2O4 (0 ≤ x ≤ 0.3) have been prepared to investigate the optical and magnetic properties. Linear variation of the lattice parameter along with the characteristic hyperfine electron paramagnetic resonance (EPR) signal establish the fact that the Mn2+ ions are incorporated at Co2+ sites of the CoAl2O4 lattice. Read More

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December 2018

A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease.

Hepatol Commun 2018 Dec 1;2(12):1467-1478. Epub 2018 Nov 1.

Division of Gastroenterology and Hepatology Beth Israel Deaconess Medical Center, Harvard Medical School Boston MA.

Nonalcoholic fatty liver disease (NAFLD) is a complex disease dictated by both genetic and environmental factors. While insulin resistance (IR) is a key pathogenic driver, two common genetic variants in patatin-like phospholipase domain containing 3 () and transmembrane 6 superfamily member 2 () also impart significant risk for disease progression. Traditional approaches to NAFLD risk stratification rely on biomarkers of fibrosis, an end result of disease progression. Read More

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December 2018

Frequency, Risk Factors, and Outcome of Gallbladder Polyps in Patients With Primary Sclerosing Cholangitis: A Case-Control Study.

Hepatol Commun 2018 Dec 13;2(12):1440-1445. Epub 2018 Nov 13.

Department of Gastroenterology/Hepatology/Nutrition Cleveland Clinic Cleveland OH.

The prevalence polyps (GBPs) in the general population has been estimated to be approximately 5%, with up to 10% of these being dysplastic or malignant. Previous studies have suggested that patients with primary sclerosing cholangitis (PSC) have increased frequency of GBPs. However, data on the prevalence, risk factors, and outcome of GBPs in these patients are sparse. Read More

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December 2018

Guar-Based Injectable Thermoresponsive Hydrogel as a Scaffold for Bone Cell Growth and Controlled Drug Delivery.

ACS Omega 2018 Nov 9;3(11):15158-15167. Epub 2018 Nov 9.

Department of Chemistry and Center for Integrative Nanotechnology Sciences, University of Arkansas at Little Rock, 2801 South University Avenue, Little Rock, Arkansas 72204, United States.

In this study, an injectable thermoresponsive hydroxypropyl guar--poly(-vinylcaprolactam) (HPG--PNVCL) copolymer was synthesized by graft polymerization. The reaction parameters such as temperature, time, monomer, and initiator concentrations were varied. In addition, the HPG--PNVCL copolymer was modified with nano-hydroxyapatite (n-HA) by in situ covalent cross-linking using divinyl sulfone (DVS) cross-linker to obtain HPG--PNVCL/n-HA/DVS composite material. Read More

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November 2018
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Alginate-Based Hydrogel Beads as a Biocompatible and Efficient Adsorbent for Dye Removal from Aqueous Solutions.

ACS Omega 2018 Nov 9;3(11):15140-15148. Epub 2018 Nov 9.

Department of Physical Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65167, Iran.

In this study, sodium alginate was employed as a starting material for preparing two kinds of biocompatible adsorbents, including calcium alginate hydrogel beads and magnetic hydrogel beads. Fourier transform infrared spectroscopy, X-ray diffraction pattern, and scanning electron microscopy/energy-dispersive X-ray techniques were used to characterize the prepared adsorbents. The performance of the prepared adsorbents for the removal of methyl violet from aqueous solution was studied in detail. Read More

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November 2018

Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension.

eNeurologicalSci 2019 Mar 22;14:24-27. Epub 2018 Nov 22.

Department of Neurology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.

Dural arteriovenous fistulas (dAVF) refer to an aberrant connection between an artery and a vein within the dura. Although the pathogenesis of dAVF is unclear, a link to cerebral venous thrombosis (CVT) has been posited though not fully identified. The current case is the first report demonstrating dAVF formation following CVT according to dynamic changes in the intracranial pressure and venous drainage pattern. Read More

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Graphene catalyzes the reversible formation of a C-C bond between two molecules.

Sci Adv 2018 Dec 14;4(12):eaau9366. Epub 2018 Dec 14.

Dep. Física de la Materia Condensada, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.

Carbon deposits are well-known inhibitors of transition metal catalysts. In contrast to this undesirable behavior, here we show that epitaxial graphene grown on Ru(0001) promotes the reversible formation of a C-C bond between -CHCN and 7,7,8,8-tetracyano--quinodimethane (TCNQ). The catalytic role of graphene is multifaceted: First, it allows for an efficient charge transfer between the surface and the reactants, thus favoring changes in carbon hybridization; second, it holds the reactants in place and makes them reactive. Read More

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December 2018

CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume.

Alzheimers Dement (Amst) 2018 2;10:782-790. Epub 2018 Nov 2.

German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

Introduction: We examined the association between cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease, neural novelty responses, and brain volume in predementia old age.

Methods: We conducted a cross-sectional analysis of the observational, multicentric DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. Seventy-six participants completed task functional magnetic resonance imaging and provided CSF (40 cognitively unimpaired, 21 experiencing subjective cognitive decline, and 15 with mild cognitive impairment). Read More

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November 2018

Radiographic Number of Positive Pelvic Lymph Nodes as a Prognostic Factor in Cervical Cancer Treated With Definitive Concurrent Chemoradiotherapy or Intensity-Modulated Radiotherapy.

Front Oncol 2018 30;8:546. Epub 2018 Nov 30.

Department of Radiation Oncology, Chi-Mei Medical Center, Tainan, Taiwan.

This study aims to assess the prognostic significance of radiographic numbers of positive pelvic lymph nodes (PLNs) in patients with cervical cancer treated with definitive concurrent chemoradiotherapy (CCRT) or intensity-modulated radiotherapy (IMRT). We conducted a retrospective study that included 164 eligible adult patients with cervical cancer who were treated with definitive CCRT or IMRT at our institution from 2009 to 2016. After exclusion of 50 patients, a total of 114 patients whose clinicopathological data and follow-up were finally analyzed. Read More

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November 2018

Two Cases with Incidental Finding of Large Asymptomatic Intradural Lumbar Tumors.

Cureus 2018 Oct 12;10(10):e3446. Epub 2018 Oct 12.

Neurological Surgery, University of Miami Hospital, Miami, USA.

Benign lumbar intradural tumors are statistically uncommon and usually present with complaints of back pain with or without radicular neurological complaints. This report involves two separate patients that were found incidentally to have large intradural tumors without any neurologic complaints. In both cases the tumors were discovered when having magnetic resonance imaging (MRI) after minor auto accidents. Read More

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October 2018
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Diagnostic performance of Gd-EOB-DTPA-enhanced MRI for evaluation of liver dysfunction: a multivariable analysis of 3T MRI sequences.

Oncotarget 2018 Nov 20;9(91):36371-36378. Epub 2018 Nov 20.

Department of Radiology, University Hospital Regensburg, Regensburg, Germany.

Objective: The aim of this study was to evaluate the diagnostic performance of a multiparametric gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MRI examination for the estimation of liver dysfunction classified by the Model for End-Stage Liver Disease (MELD) score.

Results: Liver dysfunction can be assessed by different methods. In a logistic regression analysis, T1- and T2-weighted images were affected by impaired liver function. Read More

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November 2018

A Label-fusion-aided Convolutional Neural Network for Isointense Infant Brain Tissue Segmentation.

Proc IEEE Int Symp Biomed Imaging 2018 Apr 24;2018:692-695. Epub 2018 May 24.

Department of Biostatistics, The University of Texas MD Anderson Cancer Center Houston, TX 77030, USA.

The extremely low tissue contrast in white matter during an infant's isointense stage (6-8 months) of brain development presents major difficulty when segmenting brain image regions for analysis. We sought to develop a label-fusion-aided deep-learning approach for automatically segmenting isointense infant brain images into white matter, gray matter and cerebrospinal fluid using T1- and T2-weighted magnetic resonance images. A key idea of our approach is to apply the fully convolutional neural network (FCNN) to individual brain regions determined by a traditional registration-based segmentation method instead of training a single model for the whole brain. Read More

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"Cell-addictive" dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway.

Theranostics 2018 29;8(19):5469-5481. Epub 2018 Oct 29.

School of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.

α-synclein (αS) aggregation is a representative molecular feature of the pathogenesis of Parkinson's disease (PD). Epigallocatechin gallate (EGCG) can prevent αS aggregation . However, the effects of PD treatment are poor due to the obstacles of EGCG accumulation in dopaminergic neurons, such as the blood brain barrier and high binding affinities between EGCG and membrane proteins. Read More

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October 2018

Functional Connectivity of Anterior Insula Predicts Recovery of Patients With Disorders of Consciousness.

Front Neurol 2018 30;9:1024. Epub 2018 Nov 30.

Department of Neurology and Brain Medical Centre, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

We hypothesize that the anterior insula is important for maintenance of awareness. Here, we explored the functional connectivity alterations of the anterior insula with changes in the consciousness level or over time in patients with disorders of consciousness (DOC) and determined potential correlation with clinical outcomes. We examined 20 participants (9 patients with DOC and 11 healthy controls). Read More

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November 2018

Does Resting Motor Threshold Predict Motor Hand Recovery After Stroke?

Front Neurol 2018 29;9:1020. Epub 2018 Nov 29.

Institut du Cerveau et de la Moelle épinière, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Paris, France.

Resting Motor threshold (rMT) is one of the measurement obtained by Transcranial Magnetic Stimulation (TMS) that reflects corticospinal excitability. As a functional marker of the corticospinal pathway, the question arises whether rMT is a suitable biomarker for predicting post-stroke upper limb function. To that aim, we conducted a systematic review of relevant studies that investigated the clinical significance of rMT in stroke survivors by using correlations between upper limb motor scores and rMT. Read More

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November 2018

A Longitudinal Multimodal Neuroimaging Study to Examine Relationships Between Resting State Glutamate and Task Related BOLD Response in Schizophrenia.

Front Psychiatry 2018 29;9:632. Epub 2018 Nov 29.

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.

Previous studies have observed impairments in both brain function and neurometabolite levels in schizophrenia. In this study, we investigated the relationship between brain activity and neurochemistry in off-medication patients with schizophrenia and if this relationship is altered following antipsychotic medication by combining proton magnetic resonance spectroscopy (1H-MRS) with functional magnetic resonance imaging (fMRI). We used single voxel MRS acquired in the bilateral dorsal anterior cingulate cortex (ACC) and fMRI during performance of a Stroop color-naming task in 22 patients with schizophrenia (SZ), initially off-medication and after a 6-week course of risperidone, and 20 matched healthy controls (HC) twice, 6 weeks apart. Read More

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November 2018

Neural Correlates of Orthographic Access in Mandarin Chinese Writing: An fMRI Study of the Word-Frequency Effect.

Front Behav Neurosci 2018 30;12:288. Epub 2018 Nov 30.

Key Laboratory of Behavioral Science, Center for Brain Science and Learning Difficulties, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.

Writing is an essential tool for human communication and involves multiple linguistic, cognitive, and motor processes. Chinese, a logographic writing system, differs remarkably from the writing systems of alphabetic languages. The neural substrates of Chinese writing are largely unknown. Read More

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November 2018
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