3,368 results match your criteria Magnetic Resonance Mammography


High-risk breast cancer surveillance with MRI: 10-year experience from the German consortium for hereditary breast and ovarian cancer.

Breast Cancer Res Treat 2019 Feb 6. Epub 2019 Feb 6.

Center of Familial Breast and Ovarian Cancer, University Hospital Cologne, Cologne, Germany.

Purpose: To report on 10 years of high-risk service screening with annual MRI in the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC).

Methods: A cohort of 4,573 high-risk, previously unaffected women (954 BRCA1 carriers, 598 BRCA2 carriers, 3021 BRCA1/2 non-carriers) participating in the GC-HBOC surveillance program was prospectively followed. Screening outcomes for 14,142 screening rounds with MRI between 2006 and 2015 were analyzed and stratified by risk group, type of screening round, and age. Read More

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http://dx.doi.org/10.1007/s10549-019-05152-9DOI Listing
February 2019
2 Reads

MRI breast screening revisited.

J Magn Reson Imaging 2019 Jan 28. Epub 2019 Jan 28.

Department of Radiology, NYU School of Medicine, New York, New York, USA.

Contrast-enhanced breast MRI is a standard evidence-based component of supplemental screening in conjunction with mammography for higher-risk populations because of its high sensitivity for detecting breast cancer; the use of breast MRI for screening in high-risk populations is recommended in multiple national and international guidelines. The current MRI exam, however, is expensive relative to other screening technologies such as mammography, and relatively more time-intensive. Recent investigations have focused on techniques that have the potential for improving efficiency of the breast MRI exam, decreasing acquisition and reading times, without impacting diagnostic accuracy. Read More

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http://dx.doi.org/10.1002/jmri.26547DOI Listing
January 2019
1 Read

[A Case of Invasive Ductal Carcinoma with Paget's Disease of the Breast].

Gan To Kagaku Ryoho 2018 Dec;45(13):1842-1844

Dept. of Breast and Endocrine Surgery, Osaka City University Graduate School of Medicine.

Paget's disease of the breast is usually localized in the nipple epidermis and lactiferous duct located near the nipple. Here, we report a rare case of synchronous breast carcinoma with Paget's disease and invasive ductal carcinoma. A 50-year-old woman was admitted to our hospital because of abnormalities in screening mammography findings. Read More

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December 2018
4 Reads

Abbreviated Magnetic Resonance Imaging (MRI) for Breast Cancer Screening: Rationale, Concept, and Transfer to Clinical Practice.

Annu Rev Med 2019 Jan;70:501-519

Department of Diagnostic and Interventional Radiology, RWTH Aachen University, 52074 Aachen, Germany; email:

Given the increasing understanding of cancer as a heterogeneous group of diseases, detection methods should offer a sensitivity profile that ensures perfect sensitivity for biologically important cancers while screening out self-limiting pseudocancers. However, mammographic screening is biased toward detection of ductal carcinoma in situ and slowly growing cancers-and thus frequently fails to detect biologically aggressive cancers. This explains the persistently high rates of interval cancers and high rates of breast cancer mortality observed in spite of decades of mammographic screening. Read More

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http://dx.doi.org/10.1146/annurev-med-121417-100403DOI Listing
January 2019

Preoperative imaging for breast conservation surgery-do we need more than conventional imaging for local disease assessment?

Authors:
Eugene Ong

Gland Surg 2018 Dec;7(6):554-559

Diagnostic Radiology, Mount Elizabeth Novena Hospital, Singapore.

Breast conservation surgery (BCS) is offered for early breast cancer. Conventional imaging with mammography and ultrasound would have been performed prior to surgery. This article considers other imaging modalities available [such as 3D tomosynthesis, magnetic resonance imaging (MRI), contrast-enhanced spectral mammography, positron emission mammography (PEM), breast-specific gamma imaging (BSGI) and cone beam computed tomography (CBCT)] and discusses the evidence for these in terms of diagnostic accuracy and clinical outcomes. Read More

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http://dx.doi.org/10.21037/gs.2018.08.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323257PMC
December 2018

Inflammatory breast cancer: no longer an absolute contraindication for breast conservation surgery following good response to neoadjuvant therapy.

Gland Surg 2018 Dec;7(6):520-524

Edinburgh Breast Unit, NHS Lothian, Western General Hospital, Edinburgh, UK.

Inflammatory breast cancer (IBC) is a rare form of breast cancer characterised by an erythematous swollen breast with extensive oedema and has in the past been associated with a very poor prognosis. After diagnosis by core biopsy of the cancer and any involved nodes patients in the Edinburgh Breast Unit (EBU) are primarily managed with neoadjuvant systemic therapy-chemotherapy or endocrine therapy. If the cancer is localised to one or a few well defined lesions then each of these lesions together with the lowest involved node are clipped. Read More

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http://dx.doi.org/10.21037/gs.2018.08.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323256PMC
December 2018
1 Read

Usefulness of automated breast volume scanner (ABVS) for monitoring tumor response to neoadjuvant treatment in breast cancer patients: preliminary results.

Eur Rev Med Pharmacol Sci 2019 Jan;23(1):225-231

Dipartimento di Scienze Radiologiche, Istituto di Radiologia, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Objective: We investigated the accuracy of Automated Breast Volume Scanner (ABVS) compared to handheld ultrasound (HHUS) for monitoring tumor response to neoadjuvant treatment (NAT) in breast cancer (BC).

Patients And Methods: All the patients submitted to biopsy in our Institution, from January 2017 to May 2017, proven invasive BC and eligible for NAT, were enrolled in this prospective study. The participants underwent ABVS, HHUS, dynamic contrast-enhanced Magnetic Resonance Imaging (DCE-MRI) and mammography at the beginning of NAT and ABVS, HHUS and DCE-MRI at the halfway point of therapy and before the surgery. Read More

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http://dx.doi.org/10.26355/eurrev_201901_16768DOI Listing
January 2019

Population-Based Assessment of the Association Between Magnetic Resonance Imaging Background Parenchymal Enhancement and Future Primary Breast Cancer Risk.

J Clin Oncol 2019 Jan 9:JCO1800378. Epub 2019 Jan 9.

2 University of California, San Francisco, San Francisco, CA.

Purpose: To evaluate comparative associations of breast magnetic resonance imaging (MRI) background parenchymal enhancement (BPE) and mammographic breast density with subsequent breast cancer risk.

Patients And Methods: We examined women undergoing breast MRI in the Breast Cancer Surveillance Consortium from 2005 to 2015 (with one exam in 2000) using qualitative BPE assessments of minimal, mild, moderate, or marked. Breast density was assessed on mammography performed within 5 years of MRI. Read More

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http://ascopubs.org/doi/10.1200/JCO.18.00378
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http://dx.doi.org/10.1200/JCO.18.00378DOI Listing
January 2019
4 Reads

Charcoal granuloma mimicking breast cancer: an emerging diagnosis.

Acta Radiol Open 2018 Dec 6;7(12):2058460118815726. Epub 2018 Dec 6.

Department of Gynecology, Hospital de Clinicas, Federal University of Parana, Curitiba, Brazil.

Background: Image-guided charcoal injection in suspicious breast lesions for preoperative localization is a procedure that has been increasing over the years because it is safer, faster, and more affordable when compared to needle-wire preoperative localization. To date, no complications have been associated with the method. However, in recent years there have been some reports about charcoal granulomas mimicking malignant lesions in some postoperative patients or in a conservative follow-up. Read More

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http://journals.sagepub.com/doi/10.1177/2058460118815726
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http://dx.doi.org/10.1177/2058460118815726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299914PMC
December 2018
2 Reads

A Retrospective Study of the Imaging and Pathological Features of Metaplastic Breast Carcinoma and Review of the Literature.

Med Sci Monit 2019 Jan 8;25:248-258. Epub 2019 Jan 8.

Department of Radiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning, China (mainland).

BACKGROUND Metaplastic breast cancer (MBC) is a rare type of breast cancer, characterized histologically by the presence of two or more malignant cell types (epithelial and mesenchymal). This retrospective study aimed to review the imaging and histological features of MBC, with a review of the literature. MATERIAL AND METHODS Nineteen patients with MBC (age range, 28-75 years; mean, 55 years) underwent review of their clinical records, histopathology, immunohistochemistry, and imaging findings, which included mammography, sonography, and magnetic resonance imaging (MRI) with T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and diffusion restriction determined by the apparent diffusion coefficient (ADC) and a time-intensity curve (TIC) for signal intensity. Read More

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https://www.medscimonit.com/abstract/index/idArt/912107
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http://dx.doi.org/10.12659/MSM.912107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338010PMC
January 2019
7 Reads

Diagnostic Value of Contrast-Enhanced Digital Mammography versus Contrast-Enhanced Magnetic Resonance Imaging for the Preoperative Evaluation of Breast Cancer.

J Breast Cancer 2018 Dec 26;21(4):453-462. Epub 2018 Dec 26.

Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: This study aimed to compare the diagnostic performance of contrast-enhanced digital mammography (CEDM) and contrast-enhanced magnetic resonance imaging (CEMRI) in preoperative evaluations, and to evaluate the effect of each modality on the surgical management of women with breast cancer.

Methods: This single-center, prospective study was approved by the Institutional Review Board, and informed consent was obtained from all patients. From November 2016 to October 2017, 84 patients who were diagnosed with invasive carcinoma (69/84) and ductal carcinoma (15/84), and underwent both CEDM and CEMRI, were enrolled. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4048/jbc.2018.21
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http://dx.doi.org/10.4048/jbc.2018.21.e62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310721PMC
December 2018
5 Reads

Imaging and Clinical Features of an Unusual Unilateral Breast Enlargement Diagnosed as Fibrocystic Change: A Case Report.

Am J Case Rep 2018 Dec 31;19:1550-1555. Epub 2018 Dec 31.

Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

BACKGROUND Breasts are assumed to be symmetrical bilaterally, and abnormal findings on breast imaging are largely based on such an assumption. Clinically noticeable breast asymmetry beyond that of normal range is rarely encountered. CASE REPORT A 38-year-old female presented with unilateral enlargement of her left breast for 3 months and complained of polymenorrhea twice a month. Read More

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http://dx.doi.org/10.12659/AJCR.913456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324867PMC
December 2018

Towards cross-modal organ translation and segmentation: A cycle- and shape-consistent generative adversarial network.

Med Image Anal 2019 Feb 19;52:174-184. Epub 2018 Dec 19.

J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, 32611, USA. Electronic address:

Synthesized medical images have several important applications. For instance, they can be used as an intermedium in cross-modality image registration or used as augmented training samples to boost the generalization capability of a classifier. In this work, we propose a generic cross-modality synthesis approach with the following targets: 1) synthesizing realistic looking 2D/3D images without needing paired training data, 2) ensuring consistent anatomical structures, which could be changed by geometric distortion in cross-modality synthesis and 3) more importantly, improving volume segmentation by using synthetic data for modalities with limited training samples. Read More

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http://dx.doi.org/10.1016/j.media.2018.12.002DOI Listing
February 2019

Is it worth to perform preoperative MRI for breast cancer after mammography, tomosynthesis and ultrasound?

Magn Reson Imaging 2019 Apr 20;57:317-322. Epub 2018 Dec 20.

Department of Radiology, Clínica Universidad de Navarra, Pamplona, Navarra, Spain. Electronic address:

Background: The use of preoperative breast MRI remains controversial despite being the most sensitive technique for the detection of breast malignancies.

Purpose: To evaluate the benefit of preoperative breast MRI after performing the three conventional techniques (DM, US, DBT). To analyze the influence of breast density in the sensitivity of the different imaging techniques. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0730725X183050
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http://dx.doi.org/10.1016/j.mri.2018.12.005DOI Listing
April 2019
2 Reads
2.022 Impact Factor

Mutations and Breast Cancer Prevention.

Cancers (Basel) 2018 Dec 19;10(12). Epub 2018 Dec 19.

Women's College Research Institute, Women's College Hospital, 76 Grenville Street, 6th Floor, Toronto, ON M5S 1B2, Canada.

Women who inherit a deleterious or mutation face substantially increased risks of developing breast cancer, which is estimated at 70%. Although annual screening with magnetic resonance imaging (MRI) and mammography promotes the earlier detection of the disease, the gold standard for the primary prevention of breast cancer remains bilateral mastectomy. In the current paper, I review the evidence regarding the management of healthy mutation carriers, including key risk factors and protective factors, and also discuss potential chemoprevention options. Read More

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http://dx.doi.org/10.3390/cancers10120524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315560PMC
December 2018
3 Reads

Sarcomas of the breast: findings on mammography, ultrasound, and magnetic resonance imaging.

Radiol Bras 2018 Nov-Dec;51(6):401-406

Department of Radiology and Oncology, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.

Sarcomas of the breast belong to a heterogeneous group of breast tumors of mesenchymal origin, without epithelial components. These tumors can be primary or secondary (after previous treatment for breast cancer), are rare, present aggressive behavior, and have a poor prognosis. They occur mainly in women between 45 and 50 years of age, with the exception of angiosarcomas, which can occur in younger patients. Read More

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http://dx.doi.org/10.1590/0100-3984.2016.0141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290740PMC
December 2018
1 Read

Prognostic factors predicting recurrence in invasive breast cancer: An analysis of radiological and clinicopathological factors.

Asian J Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Background/objective: The purpose of this study was to perform a comprehensive analysis of the radiological and clinicopathological factors that could predict recurrence of invasive breast cancer who underwent curative surgery without neoadjuvant chemotherapy.

Methods: Three hundred and sixty-four consecutive women who underwent preoperative mammography, ultrasound, and breast magnetic resonance imaging for newly diagnosed invasive breast cancers and curative surgery between January and December 2010 were included. We analyzed the radiological findings of each modality and reviewed the histopathological features. Read More

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http://dx.doi.org/10.1016/j.asjsur.2018.10.009DOI Listing
December 2018
3 Reads

FDG PET/CT and Conventional Imaging Methods in Cancer of Unknown Primary: an Approach to Overscanning.

Nucl Med Mol Imaging 2018 Dec 12;52(6):438-444. Epub 2018 Sep 12.

4Department of Nuclear Medicine, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Purpose: To compare the performance of fluorine-18 fluorodeoxyglucose positron emission tomography and computed tomography (FDG PET/CT) with conventional imaging methods (CIM), including computed tomography (CT), magnetic resonance imaging (MRI), and mammography (MMG) in cancer of unknown primary (CUP).

Methods: A total of 36 patients with CUP, who referred to our clinic for a FDG PET/CT scan, were enrolled in this study. Thirty of the patients were also examined through either diagnostic CT/MRI and/or MMG. Read More

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http://dx.doi.org/10.1007/s13139-018-0544-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261859PMC
December 2018

Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI).

Biomed Res Int 2018 8;2018:8531916. Epub 2018 Nov 8.

School of Medicine, University of Brasilia, Brasília, DF, Brazil.

Objective: To evaluate the performance of contrast-enhanced mammography (CEM) compared to magnetic resonance imaging (MRI) for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in women with newly diagnosed breast cancer.

Methods: The institutional review board approved this study. This prospective study included women with newly diagnosed breast cancer who underwent breast CEM and MRI at the end of the last cycle of NAC and before definitive surgery. Read More

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http://dx.doi.org/10.1155/2018/8531916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250019PMC
November 2018
1 Read

Diagnostic Value of Contrast-Enhanced Spectral Mammography in Comparison to Magnetic Resonance Imaging in Breast Lesions.

J Comput Assist Tomogr 2018 Dec 7. Epub 2018 Dec 7.

From the Department of Radiology and.

Objective: The aim of this study was to evaluate the diagnostic value between contrast-enhanced spectral mammography (CESM) and breast magnetic resonance imaging (MRI) in breast disease.

Methods: Two hundred thirty-five patients who were suspected of having breast abnormalities by clinical examination or mammography underwent CESM and MRI examination. Using histopathologic results as the criterion standard, the diagnostic performance of CESM and MRI was investigated. Read More

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http://Insights.ovid.com/crossref?an=00004728-900000000-9916
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http://dx.doi.org/10.1097/RCT.0000000000000832DOI Listing
December 2018
6 Reads

A Pictorial Review of Sonography of Intramammary Lymph Nodes: When to Care and What to Do About It.

Ultrasound Q 2018 Dec 3. Epub 2018 Dec 3.

Departments of Diagnostic Radiology.

This pictorial essay reviews and illustrates benign and malignant features of intramammary lymph nodes on mammography, ultrasound, and magnetic resonance imaging, including a review of the clinical and the prognostic significance in patients with known breast cancer. This pictorial essay discusses management suggestions for intramammary lymph nodes in patients with breast cancer. Read More

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http://dx.doi.org/10.1097/RUQ.0000000000000395DOI Listing
December 2018
6 Reads
1.400 Impact Factor

"I'm Just Guessing These Answers!" An Evaluation of the (In)Accuracy of Patient-Reported Medical History Collected as Part of a Breast Imaging Program.

J Med Imaging Radiat Sci 2018 Dec;49(4):390-396

Joint Department of Medical Imaging, Toronto, Ontario, Canada; Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.

Introduction: Hundreds of thousands of Ontario women receive breast screening imaging each year. The patient's medical history is a vital tool used to personalize breast screening approaches. This study evaluated the accuracy of self-reported medical and imaging history in patients about to receive breast imaging procedures in a large urban Canadian hospital. Read More

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http://dx.doi.org/10.1016/j.jmir.2018.03.002DOI Listing
December 2018
3 Reads

Screening BRCA1 and BRCA2 Mutation Carriers for Breast Cancer.

Authors:
Ellen Warner

Cancers (Basel) 2018 Nov 30;10(12). Epub 2018 Nov 30.

Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON M4N 3M5, Canada.

Women with BRCA mutations, who choose to decline or defer risk-reducing mastectomy, require a highly sensitive breast screening regimen they can begin by age 25 or 30. Meta-analysis of multiple observational studies, in which both mammography and magnetic resonance imaging (MRI) were performed annually, demonstrated a combined sensitivity of 94% for MRI plus mammography compared to 39% for mammography alone. There was negligible benefit from adding screening ultrasound or clinical breast examination to the other two modalities. Read More

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http://www.mdpi.com/2072-6694/10/12/477
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http://dx.doi.org/10.3390/cancers10120477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315500PMC
November 2018
2 Reads

Intraductal Papilloma Without Atypia on Image- Guided Breast Biopsy: Upgrade Rates to Carcinoma at Surgical Excision.

Breast Care (Basel) 2018 Oct 13;13(5):364-368. Epub 2018 Jul 13.

Institute of Radiology (RZI), Klinikum Frankfurt Höchst, Academic Teaching Hospital of the University of Frankfurt, Frankfurt/M., Germany.

Background: The management of intraductal papilloma without atypia (IDP) in breast needle biopsy remains controversial. This study investigates the upgrade rate of IDP to carcinoma and clinical and radiologic features predictive of an upgrade.

Methods: Patients with a diagnosis of IDP on image-guided (mammography, ultrasound, magnetic resonance imaging) core needle or vacuum-assisted biopsy and surgical excision of this lesion at a certified breast center between 2007 and 2017 were included in this institutional review board-approved retrospective study. Read More

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http://dx.doi.org/10.1159/000489096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257098PMC
October 2018
6 Reads

Breast imaging surveillance after curative treatment for primary non-metastasised breast cancer in non-high-risk women: a systematic review.

Insights Imaging 2018 Dec 8;9(6):961-970. Epub 2018 Nov 8.

Department of Radiology, UZ Leuven, Herestraat 49, Leuven, Belgium.

Objectives: The article summarises the available guidelines on breast imaging surveillance after curative treatment for locoregional breast cancer.

Methods: A systematic review of practice guidelines published from 1 January 2007 to 1 January 2017 was performed according to PRISMA methodology. The search was conducted for the EMBASE, MEDLINE, Cochrane and Centre for Reviews and Dissemination databases. Read More

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http://link.springer.com/10.1007/s13244-018-0667-5
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http://dx.doi.org/10.1007/s13244-018-0667-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269345PMC
December 2018
8 Reads

Comparison of mammography, digital breast tomosynthesis, automated breast ultrasound, magnetic resonance imaging in evaluation of residual tumor after neoadjuvant chemotherapy.

Eur J Radiol 2018 Nov 2;108:261-268. Epub 2018 Oct 2.

Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: To compare the accuracy of mammography (MG), digital breast tomosynthesis (DBT), automated breast ultrasound (ABUS) and magnetic resonance imaging (MRI) for the assessment of residual tumor extent in breast cancer after neoadjuvant chemotherapy (NAC).

Methods: Fifty-one stage II-III breast cancer undergoing NAC were enrolled from March 2015 to December 2016. The longest diameter of residual tumor measured with MG, DBT, ABUS and MRI was compared with the pathologic tumor size. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183034
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http://dx.doi.org/10.1016/j.ejrad.2018.09.032DOI Listing
November 2018
10 Reads

Is there a correlation between 3T multiparametric MRI and molecular subtypes of breast cancer?

Eur J Radiol 2018 Nov 24;108:120-127. Epub 2018 Sep 24.

Department of Pathology and Diagnostics - Medical Physics Unit, University Hospital of Verona, Verona, Italy.

Objectives: To test whether 3 T multiparametric magnetic resonance imaging (mMRI) provides information related to molecular subtypes of breast cancer.

Methods: Women with mammographic or US findings of breast lesions (BI-RADS 4-5) underwent 3 T mMRI (DCE, DWI and MR spectroscopy). The histological type of breast cancer was assessed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183032
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http://dx.doi.org/10.1016/j.ejrad.2018.09.024DOI Listing
November 2018
11 Reads

Use of Imaging for the Diagnosis of Idiopathic Granulomatous Mastitis: A Clinician's Perspective.

J Coll Physicians Surg Pak 2018 Nov;28(11):862-867

General Surgery Clinic, Istanbul Medicana Hospital, Bahcelievler, Istanbul, Turkey.

Idiopathic granulomatous mastitis (IGM) is an inflammatory breast disease with unknown etiology and nonspecific symptoms. Differentiation of breast cancer from granulomatous disease is a diagnostic and clinical challenge. Imaging features and decision of the surgeon, based on these findings, may be important steps during diagnosis and follow-up period. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.11.862DOI Listing
November 2018
5 Reads

Review of methods for intraoperative margin detection for breast conserving surgery.

J Biomed Opt 2018 Oct;23(10):1-19

Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States.

Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as the margins of the resected tissue are free of disease according to consensus guidelines for patient management. However, 15% to 35% of patients undergo a second surgery since malignant cells are found close to or at the margins of the original resection specimen. This review highlights imaging approaches being investigated to reduce the rate of positive margins, and they are reviewed with the assumption that a new system would need high sensitivity near 95% and specificity near 85%. Read More

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http://dx.doi.org/10.1117/1.JBO.23.10.100901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210801PMC
October 2018
13 Reads

Conservative surgery after neoadjuvant chemotherapy in patients with operable breast cancer.

Ann Ital Chir 2018 ;89:290

Neoadjuvant chemotherapy is being used with increasing frequency in the multidisciplinary treatment of patients with operable breast cancer. Although large clinical trials have shown no differences between the same systemic therapy given pre- or post-surgery on diseasefree and overall survival, neoadjuvant therapy may have several advantages. By downstaging of the tumor, chemotherapy can convert patients who are candidates for mastectomy to breast-conserving surgery candidates. Read More

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January 2018
16 Reads

Screening breast magnetic resonance imaging in women with hormone replacement therapy.

Eur J Med Res 2018 Oct 20;23(1):48. Epub 2018 Oct 20.

Department of Reproductive Endocrinology, Hangzhou Women's Hospital, Kunpeng Road 369, Hangzhou, 310008, China.

Objective: The objective of this study was to compare the performance of screening mammography versus magnetic resonance imaging (MRI) in hormone replacement therapy (HRT) users.

Methods: We performed a retrospective review of 4628 women who had mammography or breast MRI screening from the beginning of HRT use at three institutions from April 2005 to December 2015. Information of demographics, number of biopsies performed and pathologic outcomes were collected. Read More

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http://dx.doi.org/10.1186/s40001-018-0351-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195689PMC
October 2018
2 Reads

Diagnostic performance of quantitative diffusion tensor imaging for the differentiation of breast lesions at 3 T MRI.

Clin Imaging 2019 Jan - Feb;53:25-31. Epub 2018 Oct 3.

Department of Diagnostic Radiology, Medical School, University of Thessaly, Biopolis, Larissa, Greece; Department of Anatomy-Histology-Embryology, University of Thessaly Medical School, Larissa, Greece.

Background: Conventional breast magnetic resonance imaging (MRI), including dynamic contrast-enhanced MR mammography, may lead to ambiguous diagnosis and unnecessary biopsies.

Purpose: To investigate the contribution of quantitative diffusion tensor imaging (DTI) in the discrimination between benign and malignant breast lesions at 3 T MRI.

Material And Methods: The study included a total of 86 lesions (44 benign and 42 malignant) in 58 women (34 with malignant lesions, 23 with benign lesions and 1 with both types of lesions). Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.10.002DOI Listing
October 2018
2 Reads
0.600 Impact Factor

[Extramedullary Plasmacytoma].

Rofo 2018 Nov 8;190(11):1006-1009. Epub 2018 Oct 8.

Diagnostic and Interventional Radiology, Universität Leipzig Medizinische Fakultät, Leipzig, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0604-2831
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http://dx.doi.org/10.1055/a-0604-2831DOI Listing
November 2018
3 Reads

SD-CNN: A shallow-deep CNN for improved breast cancer diagnosis.

Comput Med Imaging Graph 2018 Dec 22;70:53-62. Epub 2018 Sep 22.

Department of Radiology, Mayo Clinic in Arizona, Scottsdale, AZ, 85259, USA.

Breast cancer is the second leading cause of cancer death among women worldwide. Nevertheless, it is also one of the most treatable malignances if detected early. Screening for breast cancer with full field digital mammography (FFDM) has been widely used. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08956111183023
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http://dx.doi.org/10.1016/j.compmedimag.2018.09.004DOI Listing
December 2018
15 Reads
1.500 Impact Factor

Breast cancer staging: Combined digital breast tomosynthesis and automated breast ultrasound versus magnetic resonance imaging.

Eur J Radiol 2018 Oct 5;107:188-195. Epub 2018 Sep 5.

Institute of Radiology, Department of Medicine, University of Udine, University Hospital, S. Maria della Misericordia, p.le S. Maria della Misericordia n. 15, 33100, Udine, UD, Italy. Electronic address:

Purpose: To investigate whether combined Digital breast tomosynthesis and Automated breast volume scanner (DBT-ABVS) are comparable to Magnetic resonance imaging (MRI) in staging breast cancer.

Methods: We retrospectively included seventy-three patients with histologically proven breast cancer who underwent preoperative DBT, ABVS and 1.5 T MRI in the period July 2015-July 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183030
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http://dx.doi.org/10.1016/j.ejrad.2018.09.002DOI Listing
October 2018
1 Read

Should This Woman With Dense Breasts Receive Supplemental Breast Cancer Screening?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.

Ann Intern Med 2018 Oct;169(7):474-484

Beth Israel Deaconess Medical Center, Boston, Massachusetts (G.W.S., R.B.B.).

Breast cancer will develop in 12% of women during their lifetime and is the second leading cause of cancer death among U.S. women. Read More

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http://dx.doi.org/10.7326/M18-1822DOI Listing
October 2018
3 Reads

Extraocular Muscles Involvement as the Initial Presentation in Metastatic Breast Cancer.

J Breast Cancer 2018 Sep 20;21(3):339-342. Epub 2018 Sep 20.

Department of Gynaecology, Coimbra University Hospital Centre, Coimbra, Portugal.

Orbital metastasis is a rare event, and metastatic disease affecting the extraocular muscles is an even less frequent complication of solid tumors. Herein, we report an unusual case of ptosis as the initial presentation of an invasive breast cancer. A 68-year-old woman presented with III and VI partial nerve paresis, secondary to a compressive retrobulbar mass. Read More

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http://dx.doi.org/10.4048/jbc.2018.21.e46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158159PMC
September 2018
17 Reads

Giant left breast hamartoma in a 45-year-old woman.

BMJ Case Rep 2018 Sep 30;2018. Epub 2018 Sep 30.

Department of Radiology, Eastbourne District General Hospital, Eastbourne, UK.

This is a case of a woman in her fifth decade of life who presented with a lump in her left breast. The patient underwent extensive breast investigations which did not confirm one particular diagnosis. The lesion was excised, and histological findings confirmed the diagnosis of a giant breast hamartoma. Read More

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http://dx.doi.org/10.1136/bcr-2018-226012DOI Listing
September 2018

Comparing preoperative imaging modalities in patient selection for breast intraoperative radiotherapy.

J Surg Oncol 2018 Nov 27;118(6):959-965. Epub 2018 Sep 27.

Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, New York.

Background: This study evaluated the relative accuracy of mammography, ultrasound, and magnetic resonance imaging (MRI) in predicting the tumor size of early stage breast tumors in preoperative selection of patients for intraoperative radiotherapy (IORT).

Methods: We identified 156 patients with clinical T1/T2, N0 breast cancer who underwent IORT. Clinical, pathologic, and radiation data were collected. Read More

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http://doi.wiley.com/10.1002/jso.25235
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http://dx.doi.org/10.1002/jso.25235DOI Listing
November 2018
4 Reads

Breast density implications and supplemental screening.

Eur Radiol 2018 Sep 25. Epub 2018 Sep 25.

Department of Radiology, Magee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Digital breast tomosynthesis (DBT) has been widely implemented in place of 2D mammography, although it is less effective in women with extremely dense breasts. Breast ultrasound detects additional early-stage, invasive breast cancers when combined with mammography; however, its relevant limitations, including the shortage of trained operators, operator dependence and small field of view, have limited its widespread implementation. Automated breast sonography (ABS) is a promising technique but the time to interpret and false-positive rates need to be improved. Read More

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http://link.springer.com/10.1007/s00330-018-5668-8
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http://dx.doi.org/10.1007/s00330-018-5668-8DOI Listing
September 2018
19 Reads

2-fluoro-2-deoxy-D-glucose positron emission tomography versus conventional imaging for the diagnosis of breast cancer and lymph node metastases.

J Cancer Res Ther 2018 Sep;14(Supplement):S661-S666

Department of Nuclear Medicine, Jinhua Central Hospital, Jinhua Hospital of Zhejiang University, Jinhua 321000, Zhejiang, China.

Context: Proper preoperative staging is vital in the treatment of breast cancer patients. Fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F-FDG-PET/CT) and conventional diagnostic modalities including ultrasonography (US), mammography (MG), and magnetic resonance imaging (MRI) play a greater role.

Aims: To evaluate the diagnostic accuracy of FDG-PET in detecting primary breast cancer as compared with US, MG, and MRI, and in axillary lymph nodes (ALNs) staging in Chinese women. Read More

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http://dx.doi.org/10.4103/0973-1482.207069DOI Listing
September 2018
2 Reads

Benign Breast Diseases: An Introduction for the Advanced Practice Nurse.

Authors:
Kari Mau

Clin J Oncol Nurs 2018 Oct;22(5):493-495

Georgia Southern University.

The discovery of an abnormality in the breast may provoke anxiety for patient and clinician alike. Fortunately, most lesions in the breast are benign. Physical examination and breast imaging, including mammography, ultrasound, and magnetic resonance imaging, assist in the diagnosis of benign breast diseases. Read More

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http://dx.doi.org/10.1188/18.CJON.493-495DOI Listing
October 2018
1 Read

A case of primary extraskeletal osteosarcoma of the breast.

Surg Case Rep 2018 Sep 19;4(1):121. Epub 2018 Sep 19.

Department of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku Kokurakita-ku, Kitakyushu, Fukuoka, 802-0077, Japan.

Background: Primary sarcomas of the breast are rare and account for less than 1% of all primary breast malignancies. We experienced a case of extraskeletal osteosarcoma of the breast that had a unique clinical course and remarkable findings of mammography and magnetic resonance imaging (MRI). A review of the case reports published in the past few decades showed no reports of a case in which a calcified lesion was followed up three different times on mammography, making this a valuable case report. Read More

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http://dx.doi.org/10.1186/s40792-018-0530-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146110PMC
September 2018
2 Reads

Background parenchymal enhancement in pregnancy-associated breast cancer: a hindrance to diagnosis?

Eur Radiol 2019 Mar 18;29(3):1187-1193. Epub 2018 Sep 18.

Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.

Purpose: The purpose of this study is to investigate the detectability of pregnancy-associated breast cancer (PABC) in lactating glandular tissue on magnetic resonance imaging (MRI) by using pre- and post-contrast acquisitions and their derived postprocessed images and compare these results to ultrasound (US) and mammography (MG).

Materials And Methods: We reviewed the electronic database for women with PABC and existing breast MRI. MR images (T2-weighted short inversion-recovery sequence [STIR], dynamic contrast-enhanced T1-weighted gradient echo sequence and postprocessed subtraction images [early post-contrast minus pre-contrast]) were retrospectively evaluated (image quality, parenchymal/tumour enhancement kintetics, tumour size and additional lesions). Read More

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http://dx.doi.org/10.1007/s00330-018-5721-7DOI Listing
March 2019
4 Reads

Extreme Learning Machine (ELM)-Based Classification of Benign and Malignant Cells in Breast Cancer.

Authors:
Abdullah Toprak

Med Sci Monit 2018 Sep 17;24:6537-6543. Epub 2018 Sep 17.

Department of Biomedical Engineering, Engineering Faculty, Dicle University, Diyarbakır, Turkey.

BACKGROUND Breast cancer is one of the most common cancer types in the world and is a serious threat to health. This type of cancer is complex; it is a hereditary disease and does not result from a single cause. The diagnosis of cancer starts with a biopsy. Read More

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http://dx.doi.org/10.12659/MSM.910520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154116PMC
September 2018
2 Reads

Problem-solving breast MRI: useful or a source of new problems?

Diagn Interv Radiol 2018 Sep;24(5):255-261

Department of Breast-Endocrine Surgery Güven Hospital Breast Center, Ankara, Turkey.

Purpose: We aimed to evaluate the findings and results from breast magnetic resonance imaging (MRI) examinations performed for problem-solving purposes due to inconclusive conventional imaging findings.

Methods: Imaging findings, biopsy and follow-up results were retrospectively evaluated for breast MRI performed for problem-solving purposes at our department between January 2011 and December 2016 for cases whose mammography, tomosynthesis, or ultrasonography findings were inconclusive.

Results: Lesions were identified in 414 of 986 problem-solving MRI examinations, and 13. Read More

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http://dx.doi.org/10.5152/dir.2018.17504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135053PMC
September 2018
1 Read

High rate of occult cancer found in prophylactic mastectomy specimens despite thorough presurgical assessment with MRI and ultrasound: findings from the Hereditary Breast and Ovarian Cancer Registration 2016 in Japan.

Breast Cancer Res Treat 2018 Dec 10;172(3):679-687. Epub 2018 Sep 10.

Diagnostics and Therapeutics of Intractable Disease, Juntendo University, Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.

Purpose: Prophylactic surgery is a preemptive strategy for hereditary breast and ovarian cancer (HBOC). Prophylactic mastectomy (PM) reduces breast cancer risk by > 90%. The aim of our study is to analyze the information of the Japanese pedigrees and to utilize the results for clinical practice. Read More

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http://dx.doi.org/10.1007/s10549-018-4953-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245054PMC
December 2018
3 Reads

SAVI SCOUT® localization of breast lesions as a practical alternative to wires: Outcomes and suggestions for trouble-shooting.

Clin Imaging 2018 Nov - Dec;52:280-286. Epub 2018 Jul 24.

H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA. Electronic address:

Objective: The purpose of our study was to determine the frequency of successful SAVI SCOUT® localizations, to identify the factors contributing to unsuccessful procedures, and to provide a problem-solving algorithm to address those factors.

Subjects And Methods: This retrospective study was performed following IRB approval. We included all consecutive patients with SCOUT® reflector placement performed at a single tertiary-care cancer center. Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.07.008DOI Listing
January 2019
1 Read

An all-in-one nanoparticle (AION) contrast agent for breast cancer screening with DEM-CT-MRI-NIRF imaging.

Nanoscale 2018 Sep;10(36):17236-17248

Department of Radiology, University of Pennsylvania, 3400 Spruce St, 1 Silverstein, Philadelphia, PA 19104, USA.

Conventional X-ray mammography has low diagnostic sensitivity for women with dense breasts. As a result, alternative contrast-enhanced screening tools such as dual energy mammography (DEM), computed tomography (CT), magnetic resonance imaging (MRI), and near-infrared fluorescence (NIRF) imaging are being used or investigated for these women. However, currently available contrast agents are non-ideal, have safety issues, and each imaging technique requires a different contrast agent. Read More

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http://dx.doi.org/10.1039/c8nr03741hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148383PMC
September 2018
7 Reads