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Br J Radiol 2019 Apr 24:20180929. Epub 2019 Apr 24.

1 Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of medicine , Seoul , Korea.

Objective: To compare the accuracy of contrast-enhanced digital mammography (CEDM) and MRI, including maximal intensity projection (MIP) images, for measuring the tumour size of breast cancer.

Methods: We included 52 females (mean age, 50.9 years) with surgery due to breast cancer, and measured maximum diameter of main mass on mediolateral oblique (MLO) and craniocaudal (CC) views of mammography and CEDM; sagittal, axial MIP images, and early dynamic contrast-enhanced MRI (CEMRI) before surgery. Read More

Eur J Radiol 2019 May 21;114:167-174. Epub 2019 Mar 21.

Department of Diagnostic Radiology, Unit 1350, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. Electronic address:

Objective: Different molecular subtypes of triple-negative breast cancer (TNBC) have previously been identified through analysis of gene expression profiles. The luminal androgen receptor (LAR) subtype has been shown to have a lower rate of pathologic complete response to neoadjuvant chemotherapy than other TNBC subtypes. The purpose of this study was to determine if the imaging features of TNBCs differ by AR (androgen receptor) status, which is a surrogate immunohistochemical (IHC) marker for the chemoresistant LAR subtype of TNBC. Read More

Indian J Radiol Imaging 2019 Jan-Mar;29(1):85-88

Department of Pathology, Command Hospital, Kolkata, West Bengal, India.

Primary lymphoma of breast is very rare which has no tell-tale imaging characteristics. Multimodality imaging helps not only in suggesting the possibility of lymphoma but also in its management. We present here one such case which was extensively worked up with various imaging modalities and was histologically proven as primary breast lymphoma. Read More

Breast Cancer 2019 Apr 12. Epub 2019 Apr 12.

Division of Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake Koto-ku, Tokyo, 135-8550, Japan.

Individuals carrying pathogenic BRCA1 or BRCA2 mutations have an increased lifetime risk of breast and/or ovarian cancer. The incidence of breast cancer amongst disease-free BRCA mutation carriers under surveillance and the clinical and pathological characteristics of those who subsequently develop the disease remain unclear in Japan. We reviewed the records of 155 individuals with BRCA1 or BRCA2 mutations identified by genetic testing between January 2000 and December 2016. Read More

Open Access Maced J Med Sci 2019 Mar 14;7(5):838-848. Epub 2019 Mar 14.

Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran.

One of the techniques utilised in the management of cancer in all stages is multiple biomedical imaging. Imaging as an important part of cancer clinical protocols can provide a variety of information about morphology, structure, metabolism and functions. Application of imaging technics together with other investigative apparatus including in fluids analysis and vitro tissue would help clinical decision-making. Read More

J Magn Reson Imaging 2019 Mar 27. Epub 2019 Mar 27.

Department of Magnetic Resonance Imaging, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Background: Diffusion-weighted imaging (DWI) plays an important role in the differentiation of malignant and benign breast lesions.

Purpose: To investigate the utility of various diffusion parameters obtained from monoexponential, biexponential, and stretched-exponential DWI models in the differential diagnosis of breast lesions.

Study Type: Prospective. Read More

Clin Radiol 2019 May 18;74(5):357-366. Epub 2019 Mar 18.

EPSRC Centre for Mathematical and Statistical Analysis of Multimodal Clinical Imaging, University of Cambridge, Cambridge CB3 0WA, UK; Department of Radiology, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK. Electronic address:

This article reviews current limitations and future opportunities for the application of computer-aided detection (CAD) systems and artificial intelligence in breast imaging. Traditional CAD systems in mammography screening have followed a rules-based approach, incorporating domain knowledge into hand-crafted features before using classical machine learning techniques as a classifier. The first commercial CAD system, ImageChecker M1000, relies on computer vision techniques for pattern recognition. Read More

Acta Radiol 2019 Mar 21:284185119834689. Epub 2019 Mar 21.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Background: Invasive micropapillary carcinoma (IMPC) is a rare subtype of breast cancer and is presumed to have a poorer survival outcome than invasive ductal carcinoma (IDC). However, studies for clinical outcomes including imaging features are still scarce.

Purpose: To investigate differences in clinical outcomes between IMPC and IDC and to determine prognostic factors indicating survival, including imaging features. Read More

Am J Public Health 2019 May 21;109(5):762-767. Epub 2019 Mar 21.

Susan H. Busch is with the Department of Health Policy and Management, Yale School of Public Health, New Haven, CT. Jessica R. Hoag, Jenerius A. Aminawung, Pamela R. Soulos, and Cary P. Gross are with Department of Internal Medicine, Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine, New Haven. Xiao Xu is with the Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine. Ilana B. Richman is with the Department of Internal Medicine, Yale School of Medicine. Kelly A. Kyanko is with the Department of Population Health, New York University School of Medicine, New York, NY.

Objectives: To evaluate the association of state dense breast notification (DBN) laws with use of supplemental tests and cancer diagnosis after screening mammography.

Methods: We examined screening mammograms (n = 1 441 544) performed in 2014 and 2015 among privately insured women aged 40 to 59 years living in 9 US states that enacted DBN laws in 2014 to 2015 and 25 US states with no DBN law in effect. DBN status at screening mammography was categorized as no DBN, generic DBN, and DBN that mandates notification of possible benefits of supplemental screening (DBN+SS). Read More

Acta Biomed 2019 Jan 23;90(1):11-15. Epub 2019 Jan 23.

"P.GIACCONE" University Hospital, Palermo, Italy.

Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Read More

Korean J Radiol 2019 Apr;20(4):533-541

Department of Radiology, Breast Imaging Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Breast magnetic resonance imaging (MRI) has been increasingly utilized, especially in screening for high-risk cases, because of its high sensitivity and superior ability to detect cancers as compared with mammography and ultrasound. Several limitations such as higher cost, longer examination time, longer interpretation time, and low availability have hindered the wider application of MRI, especially for screening of average-risk women. To overcome some of these limitations and increase access to MRI screening, an abbreviated breast MRI protocol has been introduced. Read More

Radiol Res Pract 2019 3;2019:5045908. Epub 2019 Feb 3.

Department of Diagnostic Radiology, American University of Beirut Medical Center, Lebanon.

Objectives: The aim of this study is to demonstrate the various imaging appearances of stromal fibrosis on mammography, ultrasound, and magnetic resonance imaging (MRI).

Material And Methods: This study included 75 female patients who presented to the American University of Beirut Medical Center between January 2010 and October 2015 for breast imaging. 66 (88%) patients obtained a mammogram, 71 (95%) had an ultrasound, and 6 (8%) had an MRI. Read More

Am Fam Physician 2019 Mar;99(6):370-375

Saint Louis University School of Medicine, St. Louis, MO, USA.

With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six months for the first three years after treatment, every six to 12 months for two more years, and annually thereafter. Read More

Ann Ital Chir 2019 ;90:1-2

Aim of this paper is to allows to analyze a topic of great relevance and media interest such as the role of prophylactic mastectomy in healthy women with BRCA mutation proposing to the surgeons some useful informations for decision-making. Less than 15% of all breast cancers are associated with germline genetic mutations. The majority of hereditary breast tumors are due to mutations in BRCA1 and BRCA2 genes that are responsible for only one third of hereditary cases. Read More

Autops Case Rep 2019 Jan-Mar;9(1):e2018071. Epub 2019 Feb 25.

Instituto Português de Oncologia do Porto, Surgical Oncology. Porto, Portugal.

Intestinal lipomatosis is rare and often asymptomatic but can present with intestinal obstruction. Occasionally, metastatic breast cancer is identified in the ovary before a breast primary is discovered. We report the case of a 50-year-old woman diagnosed with synchronous intestinal obstruction due to lipomatosis, and incidental ovarian metastases from breast cancer. Read More

Med Image Anal 2019 Feb 26;54:76-87. Epub 2019 Feb 26.

Institute of Computer Vision and Robotics, University of Girona, Spain.

Breast magnetic resonance imaging (MRI) and X-ray mammography are two image modalities widely used for early detection and diagnosis of breast diseases in women. The combination of these modalities, traditionally done using intensity-based registration algorithms, leads to a more accurate diagnosis and treatment, due to the capability of co-localizing lesions and susceptibles areas between the two image modalities. In this work, we present the first attempt to register breast MRI and X-ray mammographic images using intensity gradients as the similarity measure. Read More

Eur J Breast Health 2019 Jan 1;15(1):1-6. Epub 2019 Jan 1.

Department of Radiology, University of Texas Southwestern Medical School, Texas, USA.

Breast magnetic resonance imaging (MRI) is the most sensitive imaging method for breast cancer detection. In this review we discuss the vastly superior performance of MRI compared to traditional breast cancer screening modalities of mammography, tomosynthesis and ultrasound. We discuss an abbreviated breast MRI (AB-MRI) protocol utilizing Dixon sequences which is compliant with American College of Radiology (ACR) guidelines for accreditation of breast MRI but with significantly reduced scan times. Read More

Radiol Bras 2019 Jan-Feb;52(1):43-47

Departamento de Imagem - A.C.Camargo Cancer Center, São Paulo, SP, Brazil.

Ductal carcinoma in situ (DCIS) is a precursor mammary lesion whose malignant cells do not extend beyond the basement membrane and presents a risk of progression to malignant disease. Its early detection increased with screening mammography. The objective of this study was to review the literature on the main presentations of DCIS on magnetic resonance imaging (MRI), through searches of the Medline/PubMed, Latin-American and Caribbean Center on Health Sciences Information (Lilacs), and Scientific Electronic Library Online (SciELO) databases. Read More

Breast Care (Basel) 2018 Dec 23;13(6):413-418. Epub 2018 Nov 23.

Breast Unit, Evangelische Huyssens-Stiftung, Kliniken Essen-Mitte, Essen, Germany.

Granulomatous mastitis (GM) is a rare benign inflammatory breast disease that affects mostly women of childbearing age with a history of breastfeeding. The etiopathogenesis is still unknown; however, inflammation as the result of a reaction to trauma, metabolic or hormonal processes, autoimmunity, and an infection with have all been implicated. Clinical findings are pain, mass, hyperemia, and inflammation. Read More

Quant Imaging Med Surg 2019 Jan;9(1):63-74

Medical Engineering and Technology Center, Taishan Medical University, Taian 271016, China.

Background: Breast imaging technology plays an important role in breast cancer planning and treatment. Recently, three-dimensional (3D) printing technology has become a trending issue in phantom constructions for medical applications, with its advantages of being customizable and cost-efficient. However, there is no current practice in the field of multi-purpose breast phantom for quality control (QC) in multi-modalities imaging. Read More

Breast J 2019 Mar 14;25(2):310-311. Epub 2019 Feb 14.

Department of Radiology, Istanbul Faculty of Medicine, Fatih, Istanbul, Turkey.

Breast Cancer Res Treat 2019 Feb 6. Epub 2019 Feb 6.

Center of Familial Breast and Ovarian Cancer, University Hospital Cologne, Cologne, Germany.

Purpose: To report on 10 years of high-risk service screening with annual MRI in the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC).

Methods: A cohort of 4,573 high-risk, previously unaffected women (954 BRCA1 carriers, 598 BRCA2 carriers, 3021 BRCA1/2 non-carriers) participating in the GC-HBOC surveillance program was prospectively followed. Screening outcomes for 14,142 screening rounds with MRI between 2006 and 2015 were analyzed and stratified by risk group, type of screening round, and age. Read More

J Magn Reson Imaging 2019 May 28;49(5):1212-1221. Epub 2019 Jan 28.

Department of Radiology, NYU School of Medicine, New York, New York, USA.

Contrast-enhanced breast MRI is a standard evidence-based component of supplemental screening in conjunction with mammography for higher-risk populations because of its high sensitivity for detecting breast cancer; the use of breast MRI for screening in high-risk populations is recommended in multiple national and international guidelines. The current MRI exam, however, is expensive relative to other screening technologies such as mammography, and relatively more time-intensive. Recent investigations have focused on techniques that have the potential for improving efficiency of the breast MRI exam, decreasing acquisition and reading times, without impacting diagnostic accuracy. Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):1842-1844

Dept. of Breast and Endocrine Surgery, Osaka City University Graduate School of Medicine.

Paget's disease of the breast is usually localized in the nipple epidermis and lactiferous duct located near the nipple. Here, we report a rare case of synchronous breast carcinoma with Paget's disease and invasive ductal carcinoma. A 50-year-old woman was admitted to our hospital because of abnormalities in screening mammography findings. Read More

Annu Rev Med 2019 01;70:501-519

Department of Diagnostic and Interventional Radiology, RWTH Aachen University, 52074 Aachen, Germany; email:

Given the increasing understanding of cancer as a heterogeneous group of diseases, detection methods should offer a sensitivity profile that ensures perfect sensitivity for biologically important cancers while screening out self-limiting pseudocancers. However, mammographic screening is biased toward detection of ductal carcinoma in situ and slowly growing cancers-and thus frequently fails to detect biologically aggressive cancers. This explains the persistently high rates of interval cancers and high rates of breast cancer mortality observed in spite of decades of mammographic screening. Read More

Gland Surg 2018 Dec;7(6):554-559

Diagnostic Radiology, Mount Elizabeth Novena Hospital, Singapore.

Breast conservation surgery (BCS) is offered for early breast cancer. Conventional imaging with mammography and ultrasound would have been performed prior to surgery. This article considers other imaging modalities available [such as 3D tomosynthesis, magnetic resonance imaging (MRI), contrast-enhanced spectral mammography, positron emission mammography (PEM), breast-specific gamma imaging (BSGI) and cone beam computed tomography (CBCT)] and discusses the evidence for these in terms of diagnostic accuracy and clinical outcomes. Read More

Gland Surg 2018 Dec;7(6):520-524

Edinburgh Breast Unit, NHS Lothian, Western General Hospital, Edinburgh, UK.

Inflammatory breast cancer (IBC) is a rare form of breast cancer characterised by an erythematous swollen breast with extensive oedema and has in the past been associated with a very poor prognosis. After diagnosis by core biopsy of the cancer and any involved nodes patients in the Edinburgh Breast Unit (EBU) are primarily managed with neoadjuvant systemic therapy-chemotherapy or endocrine therapy. If the cancer is localised to one or a few well defined lesions then each of these lesions together with the lowest involved node are clipped. Read More

Eur Rev Med Pharmacol Sci 2019 Jan;23(1):225-231

Dipartimento di Scienze Radiologiche, Istituto di Radiologia, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Objective: We investigated the accuracy of Automated Breast Volume Scanner (ABVS) compared to handheld ultrasound (HHUS) for monitoring tumor response to neoadjuvant treatment (NAT) in breast cancer (BC).

Patients And Methods: All the patients submitted to biopsy in our Institution, from January 2017 to May 2017, proven invasive BC and eligible for NAT, were enrolled in this prospective study. The participants underwent ABVS, HHUS, dynamic contrast-enhanced Magnetic Resonance Imaging (DCE-MRI) and mammography at the beginning of NAT and ABVS, HHUS and DCE-MRI at the halfway point of therapy and before the surgery. Read More

Br J Radiol 2019 Mar 11;92(1095):20180810. Epub 2019 Jan 11.

5 Cedars Breast Clinic, McGill University Health Centre, Royal Victoria Hospital , Montreal, QC , Canada.

Methods:: A cross-sectional study identified cases of mucinous breast carcinoma from pathology records (2004-2012). Two radiologists classified imaging features by consensus and two pathologists classified cases into pure or mixed subtypes. Bi-variable analyses were performed using relevant statistical tests. Read More

J Clin Oncol 2019 Apr 9;37(12):954-963. Epub 2019 Jan 9.

2 University of California, San Francisco, San Francisco, CA.

Purpose: To evaluate comparative associations of breast magnetic resonance imaging (MRI) background parenchymal enhancement (BPE) and mammographic breast density with subsequent breast cancer risk.

Patients And Methods: We examined women undergoing breast MRI in the Breast Cancer Surveillance Consortium from 2005 to 2015 (with one exam in 2000) using qualitative BPE assessments of minimal, mild, moderate, or marked. Breast density was assessed on mammography performed within 5 years of MRI. Read More

Acta Radiol Open 2018 Dec 6;7(12):2058460118815726. Epub 2018 Dec 6.

Department of Gynecology, Hospital de Clinicas, Federal University of Parana, Curitiba, Brazil.

Background: Image-guided charcoal injection in suspicious breast lesions for preoperative localization is a procedure that has been increasing over the years because it is safer, faster, and more affordable when compared to needle-wire preoperative localization. To date, no complications have been associated with the method. However, in recent years there have been some reports about charcoal granulomas mimicking malignant lesions in some postoperative patients or in a conservative follow-up. Read More

Med Sci Monit 2019 Jan 8;25:248-258. Epub 2019 Jan 8.

Department of Radiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning, China (mainland).

BACKGROUND Metaplastic breast cancer (MBC) is a rare type of breast cancer, characterized histologically by the presence of two or more malignant cell types (epithelial and mesenchymal). This retrospective study aimed to review the imaging and histological features of MBC, with a review of the literature. MATERIAL AND METHODS Nineteen patients with MBC (age range, 28-75 years; mean, 55 years) underwent review of their clinical records, histopathology, immunohistochemistry, and imaging findings, which included mammography, sonography, and magnetic resonance imaging (MRI) with T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and diffusion restriction determined by the apparent diffusion coefficient (ADC) and a time-intensity curve (TIC) for signal intensity. Read More

J Breast Cancer 2018 Dec 26;21(4):453-462. Epub 2018 Dec 26.

Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: This study aimed to compare the diagnostic performance of contrast-enhanced digital mammography (CEDM) and contrast-enhanced magnetic resonance imaging (CEMRI) in preoperative evaluations, and to evaluate the effect of each modality on the surgical management of women with breast cancer.

Methods: This single-center, prospective study was approved by the Institutional Review Board, and informed consent was obtained from all patients. From November 2016 to October 2017, 84 patients who were diagnosed with invasive carcinoma (69/84) and ductal carcinoma (15/84), and underwent both CEDM and CEMRI, were enrolled. Read More

Am J Case Rep 2018 Dec 31;19:1550-1555. Epub 2018 Dec 31.

Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

BACKGROUND Breasts are assumed to be symmetrical bilaterally, and abnormal findings on breast imaging are largely based on such an assumption. Clinically noticeable breast asymmetry beyond that of normal range is rarely encountered. CASE REPORT A 38-year-old female presented with unilateral enlargement of her left breast for 3 months and complained of polymenorrhea twice a month. Read More

Med Image Anal 2019 02 19;52:174-184. Epub 2018 Dec 19.

J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, 32611, USA. Electronic address:

Synthesized medical images have several important applications. For instance, they can be used as an intermedium in cross-modality image registration or used as augmented training samples to boost the generalization capability of a classifier. In this work, we propose a generic cross-modality synthesis approach with the following targets: 1) synthesizing realistic looking 2D/3D images without needing paired training data, 2) ensuring consistent anatomical structures, which could be changed by geometric distortion in cross-modality synthesis and 3) more importantly, improving volume segmentation by using synthetic data for modalities with limited training samples. Read More

Magn Reson Imaging 2019 04 20;57:317-322. Epub 2018 Dec 20.

Department of Radiology, Clínica Universidad de Navarra, Pamplona, Navarra, Spain. Electronic address:

Background: The use of preoperative breast MRI remains controversial despite being the most sensitive technique for the detection of breast malignancies.

Purpose: To evaluate the benefit of preoperative breast MRI after performing the three conventional techniques (DM, US, DBT). To analyze the influence of breast density in the sensitivity of the different imaging techniques. Read More

Cancers (Basel) 2018 Dec 19;10(12). Epub 2018 Dec 19.

Women's College Research Institute, Women's College Hospital, 76 Grenville Street, 6th Floor, Toronto, ON M5S 1B2, Canada.

Women who inherit a deleterious or mutation face substantially increased risks of developing breast cancer, which is estimated at 70%. Although annual screening with magnetic resonance imaging (MRI) and mammography promotes the earlier detection of the disease, the gold standard for the primary prevention of breast cancer remains bilateral mastectomy. In the current paper, I review the evidence regarding the management of healthy mutation carriers, including key risk factors and protective factors, and also discuss potential chemoprevention options. Read More

Radiol Bras 2018 Nov-Dec;51(6):401-406

Department of Radiology and Oncology, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.

Sarcomas of the breast belong to a heterogeneous group of breast tumors of mesenchymal origin, without epithelial components. These tumors can be primary or secondary (after previous treatment for breast cancer), are rare, present aggressive behavior, and have a poor prognosis. They occur mainly in women between 45 and 50 years of age, with the exception of angiosarcomas, which can occur in younger patients. Read More

Asian J Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Background/objective: The purpose of this study was to perform a comprehensive analysis of the radiological and clinicopathological factors that could predict recurrence of invasive breast cancer who underwent curative surgery without neoadjuvant chemotherapy.

Methods: Three hundred and sixty-four consecutive women who underwent preoperative mammography, ultrasound, and breast magnetic resonance imaging for newly diagnosed invasive breast cancers and curative surgery between January and December 2010 were included. We analyzed the radiological findings of each modality and reviewed the histopathological features. Read More

Nucl Med Mol Imaging 2018 Dec 12;52(6):438-444. Epub 2018 Sep 12.

4Department of Nuclear Medicine, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Purpose: To compare the performance of fluorine-18 fluorodeoxyglucose positron emission tomography and computed tomography (FDG PET/CT) with conventional imaging methods (CIM), including computed tomography (CT), magnetic resonance imaging (MRI), and mammography (MMG) in cancer of unknown primary (CUP).

Methods: A total of 36 patients with CUP, who referred to our clinic for a FDG PET/CT scan, were enrolled in this study. Thirty of the patients were also examined through either diagnostic CT/MRI and/or MMG. Read More

Biomed Res Int 2018 8;2018:8531916. Epub 2018 Nov 8.

School of Medicine, University of Brasilia, Brasília, DF, Brazil.

Objective: To evaluate the performance of contrast-enhanced mammography (CEM) compared to magnetic resonance imaging (MRI) for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in women with newly diagnosed breast cancer.

Methods: The institutional review board approved this study. This prospective study included women with newly diagnosed breast cancer who underwent breast CEM and MRI at the end of the last cycle of NAC and before definitive surgery. Read More

J Comput Assist Tomogr 2019 Mar/Apr;43(2):245-251

From the Department of Radiology and.

Objective: The aim of this study was to evaluate the diagnostic value between contrast-enhanced spectral mammography (CESM) and breast magnetic resonance imaging (MRI) in breast disease.

Methods: Two hundred thirty-five patients who were suspected of having breast abnormalities by clinical examination or mammography underwent CESM and MRI examination. Using histopathologic results as the criterion standard, the diagnostic performance of CESM and MRI was investigated. Read More

Ultrasound Q 2019 Mar;35(1):74-78

Departments of Diagnostic Radiology.

This pictorial essay reviews and illustrates benign and malignant features of intramammary lymph nodes on mammography, ultrasound, and magnetic resonance imaging, including a review of the clinical and the prognostic significance in patients with known breast cancer. This pictorial essay discusses management suggestions for intramammary lymph nodes in patients with breast cancer. Read More

J Med Imaging Radiat Sci 2018 Dec;49(4):390-396

Joint Department of Medical Imaging, Toronto, Ontario, Canada; Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.

Introduction: Hundreds of thousands of Ontario women receive breast screening imaging each year. The patient's medical history is a vital tool used to personalize breast screening approaches. This study evaluated the accuracy of self-reported medical and imaging history in patients about to receive breast imaging procedures in a large urban Canadian hospital. Read More

Cancers (Basel) 2018 Nov 30;10(12). Epub 2018 Nov 30.

Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON M4N 3M5, Canada.

Women with BRCA mutations, who choose to decline or defer risk-reducing mastectomy, require a highly sensitive breast screening regimen they can begin by age 25 or 30. Meta-analysis of multiple observational studies, in which both mammography and magnetic resonance imaging (MRI) were performed annually, demonstrated a combined sensitivity of 94% for MRI plus mammography compared to 39% for mammography alone. There was negligible benefit from adding screening ultrasound or clinical breast examination to the other two modalities. Read More

Breast Care (Basel) 2018 Oct 13;13(5):364-368. Epub 2018 Jul 13.

Institute of Radiology (RZI), Klinikum Frankfurt Höchst, Academic Teaching Hospital of the University of Frankfurt, Frankfurt/M., Germany.

Background: The management of intraductal papilloma without atypia (IDP) in breast needle biopsy remains controversial. This study investigates the upgrade rate of IDP to carcinoma and clinical and radiologic features predictive of an upgrade.

Methods: Patients with a diagnosis of IDP on image-guided (mammography, ultrasound, magnetic resonance imaging) core needle or vacuum-assisted biopsy and surgical excision of this lesion at a certified breast center between 2007 and 2017 were included in this institutional review board-approved retrospective study. Read More

Insights Imaging 2018 Dec 8;9(6):961-970. Epub 2018 Nov 8.

Department of Radiology, UZ Leuven, Herestraat 49, Leuven, Belgium.

Objectives: The article summarises the available guidelines on breast imaging surveillance after curative treatment for locoregional breast cancer.

Methods: A systematic review of practice guidelines published from 1 January 2007 to 1 January 2017 was performed according to PRISMA methodology. The search was conducted for the EMBASE, MEDLINE, Cochrane and Centre for Reviews and Dissemination databases. Read More

Eur J Radiol 2018 Nov 2;108:261-268. Epub 2018 Oct 2.

Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: To compare the accuracy of mammography (MG), digital breast tomosynthesis (DBT), automated breast ultrasound (ABUS) and magnetic resonance imaging (MRI) for the assessment of residual tumor extent in breast cancer after neoadjuvant chemotherapy (NAC).

Methods: Fifty-one stage II-III breast cancer undergoing NAC were enrolled from March 2015 to December 2016. The longest diameter of residual tumor measured with MG, DBT, ABUS and MRI was compared with the pathologic tumor size. Read More

Eur J Radiol 2018 Nov 24;108:120-127. Epub 2018 Sep 24.

Department of Pathology and Diagnostics - Medical Physics Unit, University Hospital of Verona, Verona, Italy.

Objectives: To test whether 3 T multiparametric magnetic resonance imaging (mMRI) provides information related to molecular subtypes of breast cancer.

Methods: Women with mammographic or US findings of breast lesions (BI-RADS 4-5) underwent 3 T mMRI (DCE, DWI and MR spectroscopy). The histological type of breast cancer was assessed. Read More