38,949 results match your criteria Magnetic Resonance Imaging in Acute Stroke

Clinical Significance and Influencing Factors of Microvascular Tissue Reperfusion After Macrovascular Recanalization.

Transl Stroke Res 2022 Jun 27. Epub 2022 Jun 27.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.

The relevance of impaired microvascular tissue reperfusion despite successful macrovascular angiographic reperfusion (no-reflow) in acute ischemic stroke (AIS) remains controversial. In this study, we aimed to investigate the impact of tissue optimal reperfusion (TOR) and its influencing factors. From December 1, 2020 to December 1, 2021, AIS patients with successful recanalization (modified Thrombolysis in Cerebral Infarction score [mTICI] ≥ 2b) after mechanical thrombectomy (MT) were retrospectively reviewed. Read More

View Article and Full-Text PDF

Neutrophil Respiratory Burst: an immunological indicator of post stroke infection.

Egypt J Immunol 2022 Jul;29(3):80-89

Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Stroke is long known to be followed by a series of immunosuppressive events, and infections might be a cause of death after an acute insult of stroke. The aim of our work was to assess the percentage of neutrophils showing spontaneous oxidative burst in patients with acute ischemic stroke. The study included 30 patients with acute cerebral infarction subjected to the following: magnetic resonance imaging of the brain immediately on admission, and blood sampling on day one of admission (baseline) and after 3 days of admission. Read More

View Article and Full-Text PDF

MRI Assessment of Cardiac Function and Morphology in Adult Patients With Growth Hormone Deficiency: A Systematic Review and Meta-Analysis.

Front Endocrinol (Lausanne) 2022 10;13:910575. Epub 2022 Jun 10.

Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, Turin, Italy.

Background: Adult GH deficiency (GHD) has been described as a heterogeneous condition characterized by many clinical modifications, such as metabolic alterations, impaired quality of life, and increased mortality. The clinical relevance of cardiac involvement remains, however, only partially elucidated.

Methods: PubMed/Medline, EMBASE, Cochrane library, OVID and CINAHL databases were systematically searched until February 2022 for studies evaluating cardiac function and morphology by magnetic resonance imaging in adult patients with GHD. Read More

View Article and Full-Text PDF

Machine Learning-Based Model for Prediction of Hemorrhage Transformation in Acute Ischemic Stroke After Alteplase.

Front Neurol 2022 10;13:897903. Epub 2022 Jun 10.

Department of Neurology, ZhongDa Hospital Southeast University (JiangBei) (NanJing DaChang Hospital), Nanjing, China.

Hemorrhage transformation (HT) is the most dreaded complication of intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). The prediction of HT after IVT is important in the treatment decision-making for AIS. We designed and compared different machine learning methods, capable of predicting HT in AIS after IVT. Read More

View Article and Full-Text PDF

Hyperthermic Brain Injury: Characteristic Magnetic Resonance Imaging Findings and Implications for Pathophysiology.

Neurohospitalist 2022 Jul 11;12(3):575-576. Epub 2022 Mar 11.

Department of Neurology, Tufts University School of Medicine, Boston, MA, USA.

View Article and Full-Text PDF

Dural Arteriovenous Fistula as a Reversible Cause of Progressive Parkinsonism and Dementia: A Case Report.

Neurohospitalist 2022 Jul 27;12(3):559-562. Epub 2022 Apr 27.

Neuroradiology Unit, San Camillo-Forlanini Hospital, Rome, Italy.

A dural arteriovenous fistula (DAVF) is an abnormal direct connection between an intracranial artery and the dural venous sinus. In rare cases, DAVF might show rapidly progressive dementia onset with extrapyramidal signs, often misdiagnosed as Parkinson disease or vascular parkinsonism and, therefore, pharmacological treatments are ineffective. Here, we report the case of 84-year-old man with rapidly progressive parkinsonism and dementia who was initially treated with levodopa without any improvement. Read More

View Article and Full-Text PDF

Stroke-Like Migraine Attacks After Radiation Therapy Syndrome and Radiation Necrosis After Cerebral Proton Beam Radiation: A Case Report of Dual Radiotherapy Complications.

Neurohospitalist 2022 Jul 15;12(3):567-570. Epub 2022 May 15.

Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare, delayed complication of cranial radiation therapy that consists of migraine-like headaches and focal neurologic deficits such as visual loss, aphasia, hemiparesis, hemisensory loss, and unconsciousness. SMART syndrome may be mistaken for tumor recurrence, radiation necrosis, and stroke. Timely recognition of SMART syndrome prevents unnecessary brain biopsies and enables appropriate anticipatory guidance. Read More

View Article and Full-Text PDF

Vertebral artery stump syndrome: A 7-year follow-up case report.

Radiol Case Rep 2022 Sep 17;17(9):2923-2926. Epub 2022 Jun 17.

Department of Neurosurgery, Nakamura Memorial Hospital, South 1, West 14, Chuo-ku, Sapporo, Hokkaido 060-8570, Japan.

Vertebral artery stump syndrome is rare, but one of the most important causes of posterior circulation stroke. To our knowledge, no optimal treatment for vertebral artery stump syndrome has been established, and there are no reports of long-term follow-up. We describe a 69-year-old man with vertebral artery stump syndrome who attended our hospital because of vertigo. Read More

View Article and Full-Text PDF
September 2022

Imaging Characteristics for Predicting Cognitive Impairment in Patients With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.

Front Aging Neurosci 2022 10;14:876437. Epub 2022 Jun 10.

Department of Neurology, Mie University Graduate School of Medicine, Tsu, Japan.

Objectives: Patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) show various clinical symptoms, including migraine, recurrent stroke, and cognitive impairment. We investigated the associations between magnetic resonance imaging (MRI) markers of small vessel disease and neuropsychological tests and identified the MRI characteristics for predicting cognitive impairment in patients with CADASIL.

Methods: Subjects included 60 CADASIL patients diagnosed with genetic tests and registered in the Japanese CADASIL REDCap database between June 2016 and December 2020. Read More

View Article and Full-Text PDF

Childhood Cerebral Vasculitis : A Multidisciplinary Approach.

Clin Neuroradiol 2022 Jun 24. Epub 2022 Jun 24.

Department of Medical Imaging, Children's Hospital of Eastern Ontario (CHEO), University of Ottawa, Ottawa, Ontario, Canada.

Cerebral vasculitis is increasingly recognized as a common cause of pediatric arterial stroke. It can present with focal neurological deficits, psychiatric manifestations, seizures, and encephalopathy. The etiopathogenesis of childhood cerebral vasculitis (CCV) is multifactorial, making an inclusive classification challenging. Read More

View Article and Full-Text PDF

Baseline Hemodynamic Impairment and Revascularization Outcome in Newly Diagnosed Adult Moyamoya Disease determined by Pseudo-continuous Arterial Spin Labeling.

World Neurosurg 2022 Jun 21. Epub 2022 Jun 21.

Nanjing Comprehensive Stroke Center, Affiliated Nanjing Brain Hospital, Nanjing Medical University, 264 Guangzhou Road, Nanjing 210029, PR China. Electronic address:

Objective: The study aimed to investigate the hemodynamic features and independent predictors of neoangiogenesis after revascularization in MMD by pseudo-continuous arterial spin labeling magnetic resonance imaging (pCASL MRI).

Methods: 39 MMD patients were categorized into infarction group, hemorrhagic group and atypical group. All patients underwent combined bypass surgery and pCASL imaging with post-labeling delays (PLD) of 1525ms and 2525ms. Read More

View Article and Full-Text PDF

Paramagnetic rim lesions are associated with pathogenic CSF profiles and worse clinical status in multiple sclerosis: A retrospective cross-sectional study.

Mult Scler 2022 Jun 24:13524585221102921. Epub 2022 Jun 24.

Translational Neuroradiology Section, Division of Neuroimmunology and Neurovirology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

Background: Paramagnetic rims have been observed as a feature of some multiple sclerosis (MS) lesions on susceptibility-sensitive magnetic resonance imaging (MRI) and indicate compartmentalized inflammation.

Objective: To investigate clinical, MRI, and intrathecal (cerebrospinal fluid, CSF) associations of paramagnetic rim lesions (PRLs) using 3T MRI in MS.

Methods: This is a retrospective, cross-sectional analysis. Read More

View Article and Full-Text PDF

An evaluation of the structure and process of stroke rehabilitation in primary, secondary and tertiary hospitals in Ghana.

S Afr J Physiother 2022 23;78(1):1637. Epub 2022 May 23.

Department of Physiotherapy, School of Healthcare Sciences, University of Pretoria, Pretoria, South Africa.

Background: Evidence shows that quality indicators such as the structure and process of stroke rehabilitation can influence patient outcomes. However, not much attention has been paid to the study of these issues in low- and middle-income countries such as Ghana.

Objectives: Our study evaluated the structure and process of stroke rehabilitation in primary, secondary and tertiary hospitals in the Greater Accra Region of Ghana. Read More

View Article and Full-Text PDF

Diagnosis of adult-onset MELAS with suspected recurrent strokes: A case report.

Exp Ther Med 2022 Jul 25;24(1):466. Epub 2022 May 25.

Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.

Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is caused by mutations in mitochondrial DNA and is one of the most common syndromes among the mitochondrial diseases. Clinical manifestations typically occur before the age of 40 years. The present study reports a case of MELAS with a mutation in the adenine to guanine conversion at mitochondrial genome 3243 in a 48-year-old woman who was suspected of suffering from recurrent strokes. Read More

View Article and Full-Text PDF

Sports Imaging of COVID-19: A Multi-Organ System Review of Indications and Imaging Findings.

Sports Health 2022 Jun 23:19417381221106448. Epub 2022 Jun 23.

Department of Radiology, NYU Grossman School of Medicine, New York, New York.

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in December 2019 in Wuhan, China. Although coronavirus disease-19 (COVID-19) affects every population group, the sports community and athletes require special consideration of the effects on cardiovascular, musculoskeletal, neurologic, and respiratory systems. A comprehensive understanding of imaging indications, findings, and features of COVID-19 supports appropriate imaging utilization and effective patient management and treatment. Read More

View Article and Full-Text PDF

Transferrin-Enabled Blood-Brain Barrier Crossing Manganese-Based Nanozyme for Rebalancing the Reactive Oxygen Species Level in Ischemic Stroke.

Pharmaceutics 2022 May 25;14(6). Epub 2022 May 25.

Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, 600 Yi Shan Road, Shanghai 200233, China.

(1) Background: Acute ischemic stroke (IS) is one of the main causes of human disability and death. Therefore, multifunctional nanosystems that effectively cross the blood-brain barrier (BBB) and efficiently eliminate reactive oxygen species (ROS) are urgently needed for comprehensive neuroprotective effects. (2) Methods: We designed a targeted transferrin (Tf)-based manganese dioxide nanozyme ([email protected], MT) using a mild biomimetic mineralization method for rebalancing ROS levels. Read More

View Article and Full-Text PDF

Venous Segmental Flow Changes after Superficial Venous Intervention Demonstrating by Quantitative Phase-Contrast Magnetic Resonance Analysis: Preliminary Data from a Longitudinal Cohort Study.

J Pers Med 2022 Jun 19;12(6). Epub 2022 Jun 19.

College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.

The effects of superficial venous intervention on hemodynamics can be quantified using two-dimensional phase-contrast magnetic resonance imaging (2D PC-MRI). Twelve patients received pre- and postintervention 2D PC-MRI analysis using quantitative hemodynamic parameters. Fifteen healthy volunteers served as controls. Read More

View Article and Full-Text PDF

Melodic Intonation Therapy in Post-Stroke Non-Fluent Aphasia and Its Effects on Brain Plasticity.

J Clin Med 2022 Jun 17;11(12). Epub 2022 Jun 17.

School of Medicine, University of Málaga, 29010 Málaga, Spain.

Melodic Intonation Therapy (MIT) is one of the most well-known therapies for the rehabilitation of speech in patients with non-fluent aphasia and which is thought to promote right-hemisphere involvement in language processing. This review focuses on the study of language lateralization and/or neuroplastic reorganization with neuroimaging and/or neurophysiological techniques in non-fluent aphasic patients post-stroke during or after MIT. A systematic search was carried out according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) in databases (PubMed, Scopus, EMBASE, Dialnet, Web of Science, Cochrane) with the keywords melodic intonation therapy, neuroimaging, functional magnetic resonance, and positron emission tomography and the boolean operators AND and OR. Read More

View Article and Full-Text PDF

Nonalcoholic Fatty Liver Disease in Patients with Inherited and Sporadic Motor Neuron Degeneration.

Genes (Basel) 2022 May 24;13(6). Epub 2022 May 24.

Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.

We describe evidence of fatty liver disease in patients with forms of motor neuron degeneration with both genetic and sporadic etiology compared to controls. A group of 13 patients with motor neuron disease underwent liver imaging and laboratory analysis. The cohort included five patients with hereditary spastic paraplegia, four with sporadic amyotrophic lateral sclerosis (ALS), three with familial ALS, and one with primary lateral sclerosis. Read More

View Article and Full-Text PDF

Diagnosis of Ischemic Stroke: As Simple as Possible.

Diagnostics (Basel) 2022 Jun 13;12(6). Epub 2022 Jun 13.

Department of Radiology, Third Faculty of Medicine, Faculty Hospital Kralovske Vinohrady, Charles University, Srobarova 1150/50, 11000 Prague, Czech Republic.

The absolute majority of strokes in high-income countries, roughly 91%, are of ischemic origin. This review is focused on acute ischemic stroke (AIS) with large vessel occlusion (LVO) in the anterior circulation, which is considered the most devastating subtype of AIS. Moreover, stroke survivors impose substantial direct and indirect costs of care as well as costs due to productivity loss. Read More

View Article and Full-Text PDF

Border-Zone Infarction Due to Cerebrovascular Fibromuscular Dysplasia.

Yu-Ming Chen

Diagnostics (Basel) 2022 May 27;12(6). Epub 2022 May 27.

Department of Neurology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.

A 45-year-old male presented with acute-onset left-sided weakness and slurred speech. Non-contrast-enhanced brain magnetic resonance imaging revealed cortical and internal border-zone infarcts compatible with stroke. A survey of ischemic stroke risk factors in young adults excluded coagulopathy, vasculitis, and cardiac disease. Read More

View Article and Full-Text PDF

Role of Diffusion Tensor Imaging in Diagnosis and Estimation of Shunt Effect for Hydrocephalus in Stroke Patients: A Narrative Review.

Diagnostics (Basel) 2022 May 25;12(6). Epub 2022 May 25.

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu 42415, Korea.

Hydrocephalus is a dilatation of the brain ventricular system by the accumulation of cerebrospinal fluid within the ventricle caused by impaired cerebrospinal fluid circulation or clearance. A diagnosis of hydrocephalus at the chronic stage of stroke has been mainly made by clinical features and radiologic findings on brain computed tomography and magnetic resonance imaging. On the other hand, it could not determine the effect of hydrocephalus or shunt effect on the periventricular neural structures. Read More

View Article and Full-Text PDF

Prediction of Motor Outcome of Stroke Patients Using a Deep Learning Algorithm with Brain MRI as Input Data.

Eur Neurol 2022 Jun 23:1-7. Epub 2022 Jun 23.

Department of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

Background: Deep learning techniques can outperform traditional machine learning techniques and learn from unstructured and perceptual data, such as images and languages. We evaluated whether a convolutional neural network (CNN) model using whole axial brain T2-weighted magnetic resonance (MR) images as input data can help predict motor outcomes of the upper and lower limbs at the chronic stage in stroke patients.

Methods: We collected MR images taken at the early stage of stroke in 1,233 consecutive stroke patients. Read More

View Article and Full-Text PDF

Neuroimaging in acute ischemic stroke: Trends, disparities, and clinical impact.

Eur J Radiol 2022 Jun 18;154:110411. Epub 2022 Jun 18.

Imaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States; Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States.

Introduction: Clinical studies over the past decade expanded the eligibility criteria for endovascular therapy, with advanced imaging selection and new devices leading to higher rates of good outcomes. Herein, we explore the current trends in neuroimaging, associated factors, and impact on treatment and clinical outcomes.

Materials And Methods: This is a retrospective study of consecutive acute ischemic stroke patients, admitted to a comprehensive stroke center from 2016 to 2020. Read More

View Article and Full-Text PDF

Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper.

Clin Neurophysiol 2022 May 18;140:59-97. Epub 2022 May 18.

Department of Neurology, Fukushima Medical University, Fukushima, Japan; Fukushima Global Medical Science Centre, Advanced Clinical Research Centre, Fukushima Medical University, Fukushima, Japan.

Transcranial (electro)magnetic stimulation (TMS) is currently the method of choice to non-invasively induce neural activity in the human brain. A single transcranial stimulus induces a time-varying electric field in the brain that may evoke action potentials in cortical neurons. The spatial relationship between the locally induced electric field and the stimulated neurons determines axonal depolarization. Read More

View Article and Full-Text PDF

Aplastic or twiglike middle cerebral artery with contralateral middle cerebral artery stenosis showing transient ischemic attack: illustrative case.

J Neurosurg Case Lessons 2022 May 30;3(22):CASE22121. Epub 2022 May 30.

Neurosurgery, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Background: Aplastic or twiglike middle cerebral artery (Ap/T-MCA) is a rare anomaly characterized by a unilateral MCA occlusion with plexiform vessels that causes hemorrhagic and (less commonly) ischemic strokes. The reasons for this are rarely discussed, and thus optimal treatment for ischemic Ap/T-MCA remains controversial. Here, the authors report a case of Ap/T-MCA with transient ischemic attacks treated by bypass surgery and discuss the mechanism of ischemic development and treatment methods. Read More

View Article and Full-Text PDF

Non-invasive brain stimulation and neuroenhancement.

Clin Neurophysiol Pract 2022 25;7:146-165. Epub 2022 May 25.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Attempts to enhance human memory and learning ability have a long tradition in science. This topic has recently gained substantial attention because of the increasing percentage of older individuals worldwide and the predicted rise of age-associated cognitive decline in brain functions. Transcranial brain stimulation methods, such as transcranial magnetic (TMS) and transcranial electric (tES) stimulation, have been extensively used in an effort to improve cognitive functions in humans. Read More

View Article and Full-Text PDF

Sensorimotor Responses in Post-Stroke Hemiplegic Patients Modulated by Acupuncture at Yanglingquan (GB34): A fMRI Study Using Intersubject Functional Correlation (ISFC) Analysis.

Front Neurol 2022 6;13:900520. Epub 2022 Jun 6.

Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Motor dysfunction is common in patients with stroke. Acupuncture has become an acceptable alternative method for stroke rehabilitation. Previous studies have shown various functional connectivity changes activated by acupuncture. Read More

View Article and Full-Text PDF

An In Vivo Mouse Model to Study Blood-Brain Barrier Destabilization in the Chronic Phase of Stroke.

Methods Mol Biol 2022 ;2492:289-305

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.

Cerebral ischemic injury evokes a complex cascade of pathophysiological events at the blood-vascular-parenchymal interface. These evolve over time and space and result in progressive neurological damage. Emerging evidence suggests that blood-brain barrier (BBB) recovery and reestablishment of BBB impermeability are incomplete and that these could influence stroke injury recovery, increase the risk of new stroke occurrence, and be a solid substrate for developing vascular dementia. Read More

View Article and Full-Text PDF

Early recurrence in patients with symptomatic, non-cardioembolic, internal carotid artery occlusion.

J Stroke Cerebrovasc Dis 2022 Jun 19;31(8):106571. Epub 2022 Jun 19.

Department of Neurology, Kyoto Second Red Cross Hospital, Kyoto, Japan.

Introduction: There are limited data on the clinical course of patients with non-cardioembolic, mostly atherosclerotic, internal carotid artery occlusion (ICAO). The purpose of this study was to elucidate the frequency and underlying pathogenesis of early recurrent ischemic stroke in symptomatic non-cardioembolic ICAO.

Materials And Methods: Consecutive patients with symptomatic non-cardioembolic ICAO were retrospectively reviewed. Read More

View Article and Full-Text PDF