6,891 results match your criteria Macular Hole


Laser-induced choroidal neovascularization: A case report and some reflection on animal models for age-related macular degeneration.

Medicine (Baltimore) 2021 Jun;100(23):e26239

Department of Ophthalmology, the First Affiliated Hospital of Soochow University.

Rationale: Laser induced maculopathy includes retinal photoreceptor disruption, macular hole, macular hemorrhage, and rarely choroidal neovascularization (CNV). Here we report a case of laser induced CNV that was treated by intravitreal anti-vascular endothelial growth factor (VEGF) injection and resulted in visual improvement and CNV resolution during 1-year follow up. In addition, the case of laser induced CNV treated with intravitreal anti-VEGF injections are reviewed for the first time in literature. Read More

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Successful Treatment of Full-Thickness Macular Hole in Polypoidal Choroidal Vasculopathy with Anti-VEGF Therapy.

J Vitreoretin Dis 2020 Oct 9;4(5):433-436. Epub 2020 Mar 9.

Emory University School of Medicine, Atlanta, GA.

Purpose: To report a case of an 86-year-old man with a full thickness macular hole (FTMH) secondary to polypoidal choroidal vasculopathy (PCV) treated with bevacizumab.

Methods: A retrospective case report is presented.

Results: An 86-year-old male presented with a five-month history of metamorphopsia and decreased vision in his right eye and was found to have active exudation secondary to PCV with a concurrent FTMH. Read More

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October 2020

Comparative study of vitrectomy combined with internal limiting membrane peeling and vitrectomy combined with internal limiting membrane flap covering in idiopathic macular hole treatment: a meta-analysis and systematic review.

Ann Palliat Med 2021 May;10(5):5474-5482

The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China; Department of Ophthalmology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Background: To compare the therapeutic effects of vitrectomy (PPV) combined with the internal limiting membrane (ILM) flap coverage and PPV in combination with ILM peeling on the idiopathic large macular hole (MH), in order to better guide the treatment of large MH.

Methods: Searching was conducted within PubMed, Web of Science, Embase, CNKI, and Wanfang databases, and relevant pieces of literature between 2010 and 2020 published in English or Chinese were included.

Results: A total of 11 studies including 667 patients and 667 affected eyes were included; the effective rate of hole closure between the 2 groups were compared in 11 studies. Read More

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Epidemiology of Pars Plana Vitrectomy in the Elderly: A Retrospective 10-Year Survey of 592 Cases.

Clin Interv Aging 2021 1;16:1007-1012. Epub 2021 Jun 1.

Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.

Purpose: To report the epidemiology of the surgical indications of pars plana vitrectomy in patients aged 75 years or older.

Patients And Methods: The medical records of patients who underwent vitrectomy surgery in a single center between 2008 and 2018 were evaluated retrospectively for demographics, medical background, and surgical indications. Data on patients aged 75-85 were compared to those of patients older than 85 years and those recorded between 2008-2013 and 2014-2018. Read More

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Müller cells and astrocytes in tractional macular disorders.

Prog Retin Eye Res 2021 Jun 5:100977. Epub 2021 Jun 5.

Department of Ophthalmology and Eye Hospital, University of Leipzig, 04103, Leipzig, Germany.

Tractional deformations of the fovea mainly arise from an anomalous posterior vitreous detachment and contraction of epiretinal membranes, and also occur in eyes with cystoid macular edema or high myopia. Traction to the fovea may cause partial- and full-thickness macular defects. Partial-thickness defects are foveal pseudocysts, macular pseudoholes, and tractional, degenerative, and outer lamellar holes. Read More

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[Macular buckling for highly myopic traction maculopathy].

Zhonghua Yan Ke Za Zhi 2021 Jun;57(6):433-439

Zhongshan Ophthalmic Centre, Sun Yat-sen University, State Key Laboratory of Ophthalmology, Guangzhou 510060, China.

To observe the efficacy of macular buckling in the treatment of highly myopic traction maculopathy. Retrospective case series study. The patients with high myopia who underwent macular buckling at the Zhongshan Ophthalmic Center of Sun Yat-sen University from June 2014 to June 2019 were enrolled, including 136 males and 212 females. Read More

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Inter-observer and intra-observer reliability of the myopic traction maculopathy staging system.

Eur J Ophthalmol 2021 Jun 6:11206721211023319. Epub 2021 Jun 6.

Eyecare Clinic, Brescia, Italy.

Aim: The aim of this study is to evaluate the inter-observer and intra-observer agreement of the myopic traction maculopathy (MTM) staging system (MSS).

Methods: The agreement test for MSS was based on the evaluation of 104 optical coherence tomography (OCT) scans from 104 myopic eyes. According to the MSS, six observers were asked to identify, in each image, one among four retinal patterns and one among three foveal patterns of MTM, the presence of an outer lamellar macular hole (OLMH) and an epiretinal membrane (ERM). Read More

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Laser photocoagulation for the treatment of bilateral late-onset retinopathy of prematurity-related retinal detachment in an adult male: A case report.

Medicine (Baltimore) 2021 Jun;100(22):e26227

Department of Ophthalmology, Tri-service General Hospital, National Defense Medical Center, Taipei.

Rationale: Retinopathy of prematurity (ROP) is one of the major leading causes of childhood visual morbidity worldwide. Retinal break and traction develop in regressed ROP can further result in rhegmatogenous or tractional retinal detachment years or even decades later.

Patient Concerns: Here, we reported a case of bilateral ROP related late complication in a 36-year-old male with a chief complaint of increased floaters in his left eye. Read More

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Macular hole with inner limiting membrane peeling off spontaneously in Terson syndrome: A case report.

Medicine (Baltimore) 2021 Jun;100(22):e25960

Eye Center of the second hospital, Jilin University, ChangChun, Jilin Province, China.

Introduction: Terson's syndrome with inner limiting membrane (ILM) peeled off spontaneously is rarely seen, and the mechanism of it is not clear. Here we report a case of Terson Syndrome with a rare finding: the ILM peeled off spontaneously associated with macular hole (MH).

Patient Concerns: A 36-year-old female patient was admitted to our hospital with decreased visual acuity in the right eye lasting for 1 month. Read More

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[Reasons and risk factors for recurrent retinal detachment after removal of silicon oil in various vitreoretinal diseases].

Ophthalmologe 2021 Jun 4. Epub 2021 Jun 4.

Universitäts-Augenklinik, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg, Baldingerstrasse, Marburg, 35043, Deutschland.

Background: Pars plana vitrectomy (ppV) combined with silicone oil tamponade is a standard technique in the treatment of complicated retinal detachment. There are still recurrent cases of retinal detachment after silicone oil removal or redetachment with in situ oil tamponade.

Objective: The aim was to identify possible risk factors for retinal redetachment and to use the knowledge for optimizing treatment. Read More

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Outer retina reconstruction following inverted internal limiting membrane flap technique for large macular holes.

Saudi J Ophthalmol 2020 Jul-Sep;34(3):160-166. Epub 2021 Feb 27.

Department of Ophthalmology, Eye Foundation Retina Institute, Ikeja, Lagos, Nigeria.

Purpose: The aim of this study is to investigate the outer retina reconstruction using postoperative spectral domain optical coherence tomography (SD OCT) in large diameter macular holes (MHs) treated with the inverted internal limiting membrane (ILM) flap technique.

Methods: A retrospective study of 14 consecutive eyes that had vitrectomy and inverted ILM flap technique for MHs with a base diameter of 400 μ or greater. Preoperative and postoperative SD OCT images were assessed for MH closure and for outer retina presence; represented by the external limiting membrane (ELM) and ellipsoid zone (EZ), in the subfoveal and parafoveal areas. Read More

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February 2021

Re: Unsal . Preoperative prognostic factors for macular hole surgery: which is better? Oman J Ophthalmol 2019;12:20-4. [doi: 10.4103/ojo.OJO_247_2017].

Oman J Ophthalmol 2021 Jan-Apr;14(1):64-65. Epub 2021 Feb 27.

Department of Vitreoretinal Surgery, Vitreoretinal Service, Royal Hallamshire Hospital, Sheffield University Hospitals NHS Foundation Trust, Sheffield, United Kingdom.

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February 2021

Full-thickness macular hole formation following antivascular endothelial growth factor injection in a case of hemicentral retinal vein occlusion.

Oman J Ophthalmol 2021 Jan-Apr;14(1):49-51. Epub 2021 Feb 27.

Department of Retina and Uvea Services, Priyamvada Birla Aravind Eye Hospital, Kolkata, West Bengal, India.

A rare case reporting the occurrence of full-thickness macular hole (MH) formation following intravitreal antivascular endothelial growth factor injection in a case of hemicentral retinal vein occlusion and the subsequent management of the case. As described in few other similar case reports in the literature, there are quite a few probabilities of factors causing this pathology. An acute posterior vitreous detachment or sudden decompression of the macular edema can quite possibly lead to the above situation. Read More

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February 2021

Fugacious foveal hard exudate following full thickness macular hole.

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

Ophthalmology, LV Prasad Eye Institute Bhubaneswar Campus, Bhubaneswar, Odisha, India

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Rhegmatogenous retinal detachment with giant retinal tear in a child with Marfan's syndrome: a rare ocular emergency.

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

Ophthalmology, Government Medical College and Hospital, Chandigarh, India.

A 7-year-old boy with Marfanoid habitus presented with sudden and painless decrease in the vision of the right eye. Ocular examination revealed rhegmatogenous retinal detachment with 360° giant retinal tear in the right eye and small peripheral retinal breaks with lattice degeneration in the left eye. The patient underwent a 23-gauge pars plana vitrectomy with scleral buckling in the right eye and laser around the breaks in the left eye. Read More

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Spontaneous Closure of a Macular Hole After Nd:YAG Laser Treatment for Valsalva Retinopathy in Pregnancy.

JAMA Ophthalmol 2021 Jun 3. Epub 2021 Jun 3.

Department of Retina and Vitreous, Hangzhou Aier Eye Hospital, Zhejiang, China.

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Persistent macular holes - what is the best strategy for revision?

Graefes Arch Clin Exp Ophthalmol 2021 Jun 2. Epub 2021 Jun 2.

Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10 66280, Sulzbach, Germany.

Purpose: This study aims to analyze the success rate and functional outcome after revision surgery of persistent idiopathic full-thickness macular holes in a large patient cohort and to identify the optimal tamponade strategy and the value of new adjunctive manipulation techniques for persistent macular hole (pMH) closure.

Methods: Retrospective, comparative, non-consecutive case series of all revisional surgeries for idiopathic pMH between 2011 and 2019 at the Eye Clinic Sulzbach were identified. Of 1163 idiopathic MH surgeries, 74 eyes of 74 patients had pMH. Read More

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Antioxidant Status in the Vitreous of Eyes with Rhegmatogenous Retinal Detachment with and without Proliferative Vitreoretinopathy, Macular Hole and Epiretinal Membrane.

Life (Basel) 2021 May 19;11(5). Epub 2021 May 19.

Chair and Department of General and Pediatric Ophthalmology, Medical University of Lublin, 20-059 Lublin, Poland.

(1) Background: The aim of the study was to test the hypothesis that the antioxidant status in the vitreous body of eyes, which had been vitrectomized due to rhegmatogenous retinal detachment (RRD) with or without proliferative vitreoretinopathy (PVR), is higher than in eyes vitrectomized due to other retinal diseases. (2) Methods: four patient groups were analyzed: 22 eyes of patients with RRD without PVR, 27 eyes with RRD and PVR, 22 eyes with macular hole (MH) and 10 eyes with epiretinal membrane (ERM). Spectrophotometric methods were used to determine the total antioxidant status (TAS) values as well as superoxide dismutase (SOD) and glutathione reductase (GR) activities in the vitreous fluid samples. Read More

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Expanding the Phenotypic and Genotypic Spectrum of Bietti Crystalline Dystrophy.

Genes (Basel) 2021 May 10;12(5). Epub 2021 May 10.

Department of Ophthalmology, Federal University of São Paulo-UNIFESP, São Paulo, SP 04023-062, Brazil.

The rare form of retinal dystrophy, Bietti crystalline dystrophy, is associated with variations in , a member of the cytochrome P450 family. This study reports patients affected by typical and atypical Bietti crystalline dystrophy, expanding the spectrum of this disease. This is an observational case series of patients with a clinical and molecular diagnosis of Bietti crystalline dystrophy that underwent multimodal imaging. Read More

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Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery.

Sci Rep 2021 May 31;11(1):11351. Epub 2021 May 31.

Department of Ophthalmology, Konyang University College of Medicine, Konyang University Hospital, #158 Gwanjeodong-ro, Seo-gu, Daejeon, 35365, Republic of Korea.

To analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain optical coherence tomography (SD-OCT) was performed preoperatively and postoperatively at 1, 3, 6, 9, and 12 months. Read More

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Case of Macular Hole Secondary to Ocular Toxoplasmosis Treated Successfully by Vitrectomy with Inverted Internal Limiting Membrane Flap.

Case Rep Ophthalmol 2021 May-Aug;12(2):363-368. Epub 2021 May 10.

Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.

We report a case of ocular toxoplasmosis that developed a full-thickness macular hole (FTMH) which was successfully treated by pars plana vitrectomy combined with an inverted internal limiting membrane (ILM) flap. A 49-years-old Japanese man was aware of blurred vision in his right eye. Slit-lamp biomicroscopy, ophthalmoscopy, and optical coherence tomography (OCT) of the right eye showed that there was a grayish-white subretinal lesion at the macula accompanied by retinal exudation and mild vitreous flare and iritis. Read More

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Missing Internal Limiting Membrane during Macular Hole Repair in Alport Syndrome.

Case Rep Ophthalmol 2021 May-Aug;12(2):320-323. Epub 2021 May 3.

Westmead Hospital, Sydney, New South Wales, Australia.

The aim of this manuscript is to describe a novel retinal finding of Alport syndrome during surgical management of an associated macular hole. A retrospective chart review of a 65-year-old man with a diagnosis of Alport syndrome confirmed by renal biopsy was found to have an associated full-thickness macular hole. Pars-plana vitrectomy surgery with internal limiting membrane (ILM) peeling was attempted, but intraoperatively the ILM was found to be absent at the macula. Read More

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Posterior Segment Injuries in Operation Iraqi Freedom and Operation Enduring Freedom: 2001-2011.

Retina 2021 May 27. Epub 2021 May 27.

Department of Ophthalmology, Brooke Army Medical Center, San Antonio, TX, USA Department of Ophthalmology, Walter Reed National Military Medical Center, Bethesda, MD, USA Department of Surgery, Uniformed Services University of the Health Science, Bethesda, MD, USA Department of Ophthalmology, Wilford Hall Eye Center, San Antonio, TX, USA Department of Ophthalmology, Wake Forest Medical Center, Winston-Salem, NC, USA Department of Graduate Medical Education, Travis Air Force Base, Fairfield, CA, USA Department of Graduate Medical Education, Brooke Army Medical Center, San Antonio, TX, USA Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir, Virginia, USA Retina Group of Washington D.C., Greenbelt, MD, USA Department of Surgery, Uniformed Services University of the Health Science, Bethesda, MD, USA Department of Ophthalmology, Madigan Army Medical Center, Tacoma, WA, USA.

Objective: To characterize the nature of posterior segment ocular injuries in combat trauma.

Methods: Eyes in the Walter Reed Ocular Trauma Database were evaluated for the presence of posterior segment injury. Final visual outcomes in open- versus closed-globe injuries and by zone of injury, and the types of posterior segment injuries in open- versus closed-globe injuries were assessed. Read More

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Surgical approach in a case of unilateral retinal pigment epithelium dysgenesis and literature review.

Am J Ophthalmol Case Rep 2021 Sep 11;23:101116. Epub 2021 May 11.

Department of Ophthalmology, University of Thessaly, Larissa, Greece.

Purpose: To present a case of unilateral retinal pigment epithelium dysgenesis (URPED) complicated with tractional retinal detachment and macular hole formation, and highlight the successful anatomical and functional restoration following surgical repair. To conduct an updated review of the literature.

Observations: A 16-year-old asymptomatic female presented with a unilateral atypical peripapillary lesion of the retinal pigment epithelium (RPE) in the left eye. Read More

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September 2021

Macular hole after Nd-YAG laser capsulotomy with OCT findings.

Clin Case Rep 2021 May 15;9(5):e04267. Epub 2021 May 15.

Department of Ophthalmology Keio University School of Medicine Tokyo Japan.

Patients with incomplete posterior vitreous detachment, especially with vitreomacular adhesion, can form a macular hole after Nd-YAG laser capsulotomy. It is recommended to inform the risk of forming a macular hole before Nd-YAG laser treatment. Read More

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The efficacy and safety of ocriplasmin for patients with vitreous macular traction.

Acta Ophthalmol 2021 May 21. Epub 2021 May 21.

Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Purpose: To estimate the efficacy and safety of ocriplasmin for patients with vitreous macular traction (VMT).

Methods: The PubMed, EMBASE and Ovid were searched up to May 2020 to identify related studies. Statistical analysis was conducted by R software version 3. Read More

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Correlation of morphological characteristics of staphyloma with the structural and functional outcomes of myopic traction maculopathy after macular buckle surgery.

Indian J Ophthalmol 2021 06;69(6):1464-1468

Department of Vitreoretina, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To compare morphological features of staphyloma (type and grade) with structural and functional outcomes in 11 patients with symptomatic myopic tractional maculopathy (MTM) who underwent macular buckle surgery.

Methods: A retrospective observational case series, where a chart review was conducted of the type (Curtin classification) and grade of staphyloma (USG B-scan based). Optical coherence tomography (OCT) macula analysis done preoperatively and postoperatively 1 and 6-8 weeks), Visual acuity was recorded in log mar. Read More

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Macular associations of tilted disc syndrome.

Indian J Ophthalmol 2021 06;69(6):1451-1456

Vitreoretina, Uvea and ROP Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

Purpose: The aim of this study was to describe macular changes associated with tilted disc syndrome (TDS) using multimodality imaging.

Methods: This is a retrospective observational study of the consecutive TDS cases which were studied for macular changes using color fundus photographs and optical coherence tomography (OCT). Fundus autofluorescence, fundus fluorescein angiography, and OCT angiography were performed wherever required. Read More

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Vitreoretinal Society of India practice pattern survey 2020: Surgical retina.

Indian J Ophthalmol 2021 06;69(6):1442-1449

Vitreoretinal Society of India, Chennai, Tamil Nadu; Suven Clinical Research Center, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To present the outcomes of the Vitreo-retinal Society of India (VRSI) Practice Pattern Survey 2020 in surgical retina.

Methods: An online survey of members of VRSI was conducted in April 2020 regarding their practice patterns on varied medical and surgical retina topics concerning imaging and management approach. The results were evaluated by two independent experts in this field and compared with the evidence and other practice patterns in the world. Read More

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