6,478 results match your criteria Macular Hole


SUCCESSFUL CLOSURE OF A LARGE FULL-THICKNESS MACULAR HOLE SECONDARY TO AN IDIOPATHIC RETINAL VASOPROLIFERATIVE TUMOR USING THE INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE.

Retin Cases Brief Rep 2020 Jul 8. Epub 2020 Jul 8.

Department of Ophthalmology, University Hospital of Pointe-à-Pitre, West Indies, France.

Purpose: To report a case of large full thickness macular hole (MH) as an uncommon complication of an idiopathic retinal vasoproliferative tumor (RPVT) and the successful closure of the full-thickness MH by the inverted internal limiting membrane Flap technique.

Methods: A case report. A 40-year-old woman was referred for a progressive and profound visual loss on the right eye. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001015DOI Listing

Chronic cytomegalovirus necrotising retinitis in a patient with scleroderma and mixed connective tissue disease.

Arch Soc Esp Oftalmol 2020 Jul 9. Epub 2020 Jul 9.

Unidad de Gestión Clínica de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

The case is presented of a 52-year-old woman with scleroderma, mixed connective tissue disease, and interstitial lung disease, who developed chronic cytomegalovirus necrotising retinitis while on treatment with prednisone, mycophenolate, and hydroxychloroquine. Initially diagnosed as macular hole, the patient underwent a pars plana vitrectomy. Two months after surgery, due to progressive worsening, the diagnosis was made and treatment started (intravenous and intravitreal ganciclovir). Read More

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http://dx.doi.org/10.1016/j.oftal.2020.06.011DOI Listing

Macular hole edge morphology predicts restoration of postoperative retinal microstructure and functional outcome.

BMC Ophthalmol 2020 Jul 11;20(1):280. Epub 2020 Jul 11.

Department of Retina Center, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang Province, China.

Background: To investigate the ability of intraoperative optical coherence tomography (iOCT) during macular hole (MH) surgery to image different hole edge configurations and predict the restoration of retinal microstructure and visual outcomes.

Methods: This retrospective case series study included 53 MH patients. One eye each was assessed with iOCT during vitrectomy after internal limiting membrane (ILM) peeling. Read More

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http://dx.doi.org/10.1186/s12886-020-01541-7DOI Listing

Morphology of partial-thickness macular defects: presumed roles of Müller cells and tissue layer interfaces of low mechanical stability.

Int J Retina Vitreous 2020 6;6:28. Epub 2020 Jul 6.

Department of Ophthalmology and Eye Hospital, University of Leipzig, Liebigstrasse 10-14, 04103 Leipzig, Germany.

Background: The pathogenesis of partial-thickness macular defects and the role of Müller glial cells in the development of such defects are not well understood. We document the morphological characteristics of various types of partial-thickness macular defects using spectral-domain optical coherence tomography, with the focus on tractional and degenerative lamellar holes, and discuss possible pathogenic mechanisms.

Methods: A retrospective case series of 61 eyes of 61 patients with different types of partial-thickness macular defects is described. Read More

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http://dx.doi.org/10.1186/s40942-020-00232-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339408PMC

Macular Hole in a Patient with a Vasoproliferative Tumor.

Ophthalmol Retina 2020 07;4(7):736

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1016/j.oret.2020.03.012DOI Listing

Cryopreserved Human Amniotic Membrane Transplant in Refractory Macular Hole.

Ophthalmol Retina 2020 07;4(7):688

Department of Ophthalmology, Hospital de Santa Maria, Lisbon, Portugal.

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http://dx.doi.org/10.1016/j.oret.2020.03.002DOI Listing

Myopic macular hole detachment associated with intravitreal ocriplasmin.

Am J Ophthalmol Case Rep 2020 Sep 5;19:100697. Epub 2020 Apr 5.

Department of Ophthalmology, King's College Hospital, London, United Kingdom.

Purpose: To describe a case of macular hole retinal detachment in a high myope following intravitreal ocriplasmin injection.

Observations: A 71-year-old highly myopic (-18.63 Dioptres) female received 125 μg of intravitreal ocriplasmin (Jetrea, Oxurion, Leuven, Belgium) to treat a right, full-thickness macular hole (FTMH) with vitreomacular adhesion. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327198PMC
September 2020

Two different populations of Müller cells stabilize the structure of the fovea: an optical coherence tomography study.

Int Ophthalmol 2020 Jul 6. Epub 2020 Jul 6.

Department of Ophthalmology and Eye Hospital, University of Leipzig, Liebigstrasse 10-14, 04103, Leipzig, Germany.

Purpose: To document with spectral-domain optical coherence tomography the structural stabilization of the fovea and the sealing of outer macular defects by Müller cells.

Methods: A retrospective case series of 45 eyes of 34 patients is described.

Results: In cases of a cystic disruption of the foveola as in macular telangiectasia type 2 and vitreomacular traction, the Müller cell cone provides the structural stability of the fovea. Read More

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http://dx.doi.org/10.1007/s10792-020-01477-3DOI Listing

Evaluation of inner retinal dimples and internal limiting membrane flap configuration after temporal inverted ILM flap technique.

Eur J Ophthalmol 2020 Jul 6:1120672120940980. Epub 2020 Jul 6.

Bursa Retina Eye Hospital, Bursa, Turkey.

Purpose: To quantitatively evaluate structural changes associated with inner retinal dimples (IRDs) and qualitatively classify the internal limiting membrane (ILM) flap configuration after temporal inverted ILM flap technique using spectral domain optical coherence tomography (SD-OCT).

Methods: Twenty-three eyes of 23 patients with successfully closed idiopathic, large (>400 μm) macular hole were enrolled. Patients were treated with pars plana vitrectomy followed by temporal inverted ILM flap technique. Read More

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http://dx.doi.org/10.1177/1120672120940980DOI Listing

Optical coherence tomography angiography using the black-and-white pixel binarization histogram software: a new technique for evaluating healing of macular holes in two surgical techniques.

Int J Retina Vitreous 2020 1;6:25. Epub 2020 Jul 1.

Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.

Background: Many factors can influence the functional outcomes of macular hole surgery and some studies have tried to describe anatomical features that could predict successful treatment. The purpose of this study is to describe a new technique for evaluating the healing of macular holes after two surgical techniques using a black-and-white pixel binarization histogram software by optical coherence tomography angiography and its potential functional implications.

Methods: This was a retrospective, observational case series of patients who presented with idiopathic full-thickness macular holes and underwent vitreoretinal surgery for successful macular hole closure using the internal limiting membrane peeling technique or the inverted peeling technique or the free internal limiting membrane flap technique. Read More

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http://dx.doi.org/10.1186/s40942-020-00229-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329410PMC

Stereopsis After Unilateral Macular Hole Surgery with Internal Limiting Membrane Peeling.

Clin Ophthalmol 2020 26;14:1777-1783. Epub 2020 Jun 26.

Department of Ophthalmology, Matsumoto Dental University, Nagano, Japan.

Purpose: We have shown distinct morphological changes of the foveal retina such as horizontally asymmetrical retinal thicknesses and displacements of the fovea toward the optic disc after successful idiopathic macular hole (MH) closure by MH surgery with internal limiting membrane (ILM) peeling. The purpose of this study was to determine whether these morphological changes will alter the stereoacuity.

Setting: This was a non-randomized, retrospective study conducted on patients who underwent MH surgery at the Matsumoto Dental University Hospital, Nagano, Japan. Read More

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http://dx.doi.org/10.2147/OPTH.S257462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326205PMC

Reorganization of the perifoveal microvasculature after macular hole closure assessed via optical coherence tomography angiography.

Exp Eye Res 2020 Jun 29:108132. Epub 2020 Jun 29.

University Medical Center Goettingen, Goettingen, Germany.

Purpose: To quantify short-term microvascular changes after pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling in patients with idiopathic macular hole (IMH) using optical coherence tomography angiography (OCTA).

Design: Cohort Study.

Participants: This study included patients with IMH. Read More

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http://dx.doi.org/10.1016/j.exer.2020.108132DOI Listing

Standardized scleral buckling approach in the management of noncomplex primary rhegmatogenous retinal detachment.

Eur J Ophthalmol 2020 Jul 2:1120672120940209. Epub 2020 Jul 2.

Ophthalmology Department, Fatebenefratelli-Oftalmico Hospital, ASST-Fatebenefratelli-Sacco, Milan, Italy.

Purpose: To analyze the anatomical and functional outcomes of a standardized scleral buckling approach in patients with noncomplex primary rhegmatogenous retinal detachment (RRD).

Methods: Retrospective institutional case series of 135 eyes of 131 patients diagnosed with noncomplex primary RRD. All patients underwent scleral buckling surgery with the placement of an encircling 5 mm oval sponge at 15 ± 2 mm posteriorly from the limbus, cryopexy, subretinal fluid drainage, and air tamponade. Read More

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http://dx.doi.org/10.1177/1120672120940209DOI Listing

Evolution and visual outcomes of outer foveolar lucency after surgery for large idiopathic macular hole.

Graefes Arch Clin Exp Ophthalmol 2020 Jun 30. Epub 2020 Jun 30.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No 1, Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China.

Purpose: To explore the evolution of outer foveolar lucency (OFL) after vitrectomy and the correlation between OFL and visual acuity (VA) outcome in eyes with large idiopathic macular hole (IMH).

Methods: In this retrospective study, 244 eyes of 233 subjects with large IMH (diameter > 400 μm), who underwent vitrectomy, were included. Preoperative clinical data, postoperative optical coherence tomography (OCT) images, and VA at 1-, 4-, and 10-month visits were documented. Read More

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http://dx.doi.org/10.1007/s00417-020-04814-5DOI Listing

Comparison of Characteristics and Clinical Outcomes in 27-Gauge versus 23-Gauge Vitrectomy Surgery.

Clin Ophthalmol 2020 9;14:1553-1558. Epub 2020 Jun 9.

Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.

Purpose: To compare characteristics, clinical outcomes and complication profiles of a cohort of patients undergoing 27-gauge versus 23-gauge vitrectomy surgery at a tertiary medical center in the Middle East.

Methods: This is a retrospective comparative study of indication-matched patients undergoing 27-gauge versus 23-gauge pars plana vitrectomy for a set of predetermined diagnoses. Data including indications for surgery, clinical exams, visual outcomes, and complications were documented and analyzed. Read More

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http://dx.doi.org/10.2147/OPTH.S255162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293406PMC

Correlations between vitreous cytokine levels and inflammatory cells in fibrovascular membranes of patients with proliferative diabetic retinopathy.

Mol Vis 2020 26;26:472-482. Epub 2020 Jun 26.

Eye Hospital, University Medical Centre Ljubljana, Slovenia.

Purpose: The purpose of this study was to investigate the levels of cytokines in the vitreous, and their correlation with the density of inflammatory cells in fibrovascular membranes (FVMs) in patients with proliferative diabetic retinopathy (PDR) to evaluate intraocular inflammatory conditions with regard to disease activity.

Methods: Thirty-three patients (33 eyes) with PDR requiring vitreoretinal surgery because of FVMs and tractional detachment were enrolled in the study, and compared with 20 patients (20 eyes) with macular hole (MH; control group). All patients underwent complete ophthalmological examinations before surgery. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316633PMC

Optical coherence tomography findings in a case of macular hole treated with an autologous retinal transplant.

Arch Soc Esp Oftalmol 2020 Jun 26. Epub 2020 Jun 26.

Servicio de Retina, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera en México, Ciudad de México, México.

A case is presented of a 56-year-old female patient with a long-standing large macular hole who underwent autologous retina transplant surgery. Fundus images and spectral-domain optical coherence tomography images showed the presence of graft oedema with its corresponding hyper-reflectivity of the inner retinal layers in the first weeks of follow-up. Hyper-reflective dots later appeared mainly in the inner retinal layers. Read More

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http://dx.doi.org/10.1016/j.oftal.2020.05.026DOI Listing

Swept-Source OCT and Swept-Source OCT Angiography before and after Vitrectomy with Stuffing of the Optic Pit.

Ophthalmol Retina 2020 Apr 8. Epub 2020 Apr 8.

Ophthalmic Clinic "Jasne Blonia," Łódź, Poland.

Purpose: To identify swept-source (SS) OCT and SS OCT angiography (OCTA) patterns predicting outcome in patients with optic disc pit-associated maculopathy and to present the results of a novel surgical technique, stuffing of the optic disc pit.

Design: Prospective, interventional study.

Participants: Fifteen eyes. Read More

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http://dx.doi.org/10.1016/j.oret.2020.03.025DOI Listing

Macular morphometrics in foveal displacement following full thickness macular hole surgery.

Indian J Ophthalmol 2020 Jul;68(7):1436-1440

Department of Retina and Vitreous, Chaithanya Eye Hospital and Research Institute; CITE (Research), Trivandrum, Kerala, India.

Purpose: To investigate if the ratio of the preoperative nasal and temporal "arms" of the macular hole (MH) can have a predictive value in the magnitude of foveal displacement postoperatively.

Methods: This is retrospective interventional case series of eyes of 40 patients with full-thickness macular hole (FTMH), which underwent vitrectomy with internal limiting membrane (ILM) peeling and had Type 1 closure.All subjects underwent pre and postoperative optical coherence tomography (OCT, Heidelberg, Spectralis, Germany). Read More

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http://dx.doi.org/10.4103/ijo.IJO_1845_19DOI Listing

Macular Telangiectasia Type 2: Visual Acuity, Disease End Stage, and the MacTel Area: MacTel Project Report Number 8.

Ophthalmology 2020 Apr 21. Epub 2020 Apr 21.

Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, and Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom. Electronic address:

Purpose: To report the visual acuity measures from the macular telangiectasia type 2 (MacTel) registry and to investigate and describe phenotypic findings in eyes with substantial vision loss resulting from MacTel.

Design: Cross-sectional multicenter study.

Participants: Participants in the MacTel Natural History Observation Registration Study. Read More

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http://dx.doi.org/10.1016/j.ophtha.2020.03.040DOI Listing

Application of subretinal fluid to close refractory full thickness macular holes: treatment strategies and primary outcome: APOSTEL study.

Graefes Arch Clin Exp Ophthalmol 2020 Jun 24. Epub 2020 Jun 24.

Department of Ophthalmology, Herzog Carl Theodor Eye Clinic, Munich, Germany.

Introduction: Persisting macular holes (PMH) after surgical release of any epiretinal traction of the vitreous and adjacent membrane may rely on secondary firm adhesions between the retracted retina and adjacent retinal pigment epithelium. Secondary application of subretinal (SR)-fluid may release these adhesions followed by an anatomical closure.

Methods: Twelve surgeons applied in a consecutive case series SR-fluid in 41 eyes with PMH and reported retrospectively their initial surgical, anatomical and functional experience with this approach. Read More

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http://dx.doi.org/10.1007/s00417-020-04735-3DOI Listing
June 2020
1.908 Impact Factor

RETINAL SENSITIVITY AND VESSEL DENSITY AFTER MACULAR HOLE SURGERY WITH THE SUPERIOR INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE.

Retina 2020 Jun 17. Epub 2020 Jun 17.

Departments of Ophthalmology.

Purpose: To evaluate retinal vessel density and retinal sensitivity (RS) after macular hole surgery with the superior inverted internal limiting membrane flap technique.

Methods: Retrospective, observational case series. Twenty-one patients with idiopathic macular hole underwent 27-gauge vitrectomy with the superior inverted internal limiting membrane flap technique and triamcinolone acetonide. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002839DOI Listing

Central posterior lens capsule used instead of inverted ILM flap: a clinic-pathological case report.

Retin Cases Brief Rep 2020 Jun 15. Epub 2020 Jun 15.

Department of Ophthalmology, University of Ulm, Ulm, Germany.

Purpose: To present immunocytochemical characterization of a surgically excised central posterior lens capsule (PLC) that was transplanted to close a secondary refractory full-thickness macular hole (FTMH) as an epiretinal flap. For comparison, tissue of both an unaffected internal limiting membrane (ILM) and unexposed PLC was processed.

Methods: Clinical-pathological case report. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001030DOI Listing

An anomalous foveal OCT-sign after posterior capsule rupture in cataract surgery: Complicated cataract surgery maculopathy.

Eur J Ophthalmol 2020 Jun 21:1120672120937661. Epub 2020 Jun 21.

Ospedale Santa Maria della Misericordia, Rovigo, Italy.

Purpose: To report a series of novel optical coherence tomography (SD-OCT) foveal abnormalities, that we called "T-sign," that were noticed after a complicated cataract surgery with posterior capsule rupture and vitreous loss.

Methods: Retrospective case series of persistent foveal changes that incurred after anteroposterior vitreo-foveal traction secondary to phacoemulsification in presence of posterior capsule rupture.

Results: The study included three eyes of three patients that incurred in complicated cataract surgery and intraoperative vitreo-foveal traction. Read More

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http://dx.doi.org/10.1177/1120672120937661DOI Listing

Management of Full-Thickness Macular Hole in A Genetically Confirmed Case with Usher Syndrome.

Ophthalmol Ther 2020 Jun 21. Epub 2020 Jun 21.

1st Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.

Introduction: Full-thickness macular hole (FTMH) formation is rarely seen in patients with retinitis pigmentosa (RP) and can have an adverse impact on their residual visual function. The underlying mechanisms are unknown, and clinical experience is limited regarding surgical outcomes. Here, we describe the surgical management of FTMH in a young patient with genetically confirmed Usher syndrome, the most common form of syndromic RP. Read More

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http://dx.doi.org/10.1007/s40123-020-00276-4DOI Listing

TEMPORARY REMOVAL: Predicting post-operative vision for macular hole with automated image analysis.

Ophthalmol Retina 2020 Jun 18. Epub 2020 Jun 18.

Newcastle university, Newcastle Upon Tyne, UK; Sunderland Eye Infirmary, Sunderland, UK.

The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier. Read More

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http://dx.doi.org/10.1016/j.oret.2020.06.005DOI Listing

Simultaneous retinal pigment epithelium tear and lamellar macular hole evolving to a full-thickness macular hole after intravitreal injection.

J Fr Ophtalmol 2020 Jun 18. Epub 2020 Jun 18.

Hospital Clinic de Barcelona, Instituto Clínico de Oftalmología (ICOF), Barcelona, Spain; Department of Surgery, School of Medicine, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jfo.2019.11.010DOI Listing

High-Throughput MicroRNA Profiling of Vitreoretinal Lymphoma: Vitreous and Serum MicroRNA Profiles Distinct from Uveitis.

J Clin Med 2020 Jun 12;9(6). Epub 2020 Jun 12.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

Purpose: Vitreoretinal lymphoma (VRL) is a non-Hodgkin lymphoma of the diffuse large B cell type (DLBCL), which is an aggressive cancer causing central nervous system related mortality. The pathogenesis of VRL is largely unknown. The role of microRNAs (miRNAs) has recently acquired remarkable importance in the pathogenesis of many diseases including cancers. Read More

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http://dx.doi.org/10.3390/jcm9061844DOI Listing

Spontaneous closure of secondary eccentric macular holes following vitreoretinal surgery.

Retin Cases Brief Rep 2020 Jun 8. Epub 2020 Jun 8.

Dept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1 R Block, Chord road, Rajaji Nagar, Bengaluru - 560010. Karnataka.

Purpose: To report two cases of secondary eccentric macular holes that developed following vitrectomy and present their outcomes.

Methods: Retrospective, observational case report CASE DESCRIPTION:: A 69-year-old female and a 57-year-old male developed secondary paracentral retinal hole following vitrectomy surgery for stage 4 macular hole and proliferative diabetic retinopathy respectively. In case 1, the hole was left untreated while in case 2, laser photocoagulation was done around the paracentral retinal hole. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001027DOI Listing

Minimal internal limiting membrane peeling with ILM flap technique for idiopathic macular holes: a preliminary study.

BMC Ophthalmol 2020 Jun 15;20(1):228. Epub 2020 Jun 15.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Road, Nanjing, Jiangsu, 210029, People's Republic of China.

Background: Internal limiting membrane (ILM) peeling increases the idiopathic macular hole (IMH) closure rate but causes the inner retina dimplings. This study is to introduce a method to minimally peel the ILM, and with the ILM flap to ensure the IMH closure.

Methods: Twelve consecutive IMH eyes were treated with the minimal ILM peeling with ILM flap technique. Read More

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http://dx.doi.org/10.1186/s12886-020-01505-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296741PMC

Clinical presentation and prognostic factors affecting surgical outcomes of secondary macular holes after retinal vein occlusions.

Int Ophthalmol 2020 Jun 12. Epub 2020 Jun 12.

Department of Vitreo-Retina, Aravind Eye Hospital, Madurai, India.

Purpose: To describe clinical presentation, morphological features and surgical outcomes of macular hole (MH) secondary to retinal vein occlusion (RVO).

Method: This prospective interventional study evaluated eight eyes with atypical MH (secondary to RVO) and data regarding medical management, pars plana vitrectomy, postoperative anatomical hole closure, visual acuity improvement, morphological features of hole were noted till the last follow-up.

Results: Eight eyes with full-thickness MH in an RVO eye were followed-up for a minimum period of 3 months postoperatively. Read More

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http://dx.doi.org/10.1007/s10792-020-01465-7DOI Listing

A novel intraocular lens designed for sutureless scleral fixation: surgical series.

Graefes Arch Clin Exp Ophthalmol 2020 Jun 11. Epub 2020 Jun 11.

IRCCS Fondazione G.B. Bietti ONLUS, Rome, Italy.

Purpose: To report a retrospective series of patients implanted with a novel hydrophilic acrylic single-piece intraocular lens (IOL) designed for sutureless scleral fixation (FIL-SSF Carlevale lens, Soleko, Italy) injectable through a 2.2-mm incision.

Methods: Seventy-eight patients with minimum 6-month follow-up were divided into 6 groups: dropped nucleus, luxated IOL, trauma, aphakia, IOL exchange, and Marfan's syndrome. Read More

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http://dx.doi.org/10.1007/s00417-020-04789-3DOI Listing

A customized posterior scleral reinforcement for myopic macular hole with retinal detachment and posterior staphyloma: A case report.

Authors:
Rino Frisina

Eur J Ophthalmol 2020 Jun 8:1120672120927268. Epub 2020 Jun 8.

Department of Ophthalmology, University of Padua, Padua, Italy.

The author describes a customized posterior scleral reinforcement, its manufacturing method, the rationale of its therapeutic effect, and the surgical technique of its implantation. A 54-year-old female patient with a case history of myopic macular hole with retinal detachment and posterior staphyloma, refractory to pars plana vitrectomy and peeling of internal limiting membrane, underwent posterior scleral reinforcement treatment. Retinal reattachment and macular hole closure were obtained. Read More

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http://dx.doi.org/10.1177/1120672120927268DOI Listing

The new Myopic Traction Maculopathy Staging System.

Eur J Ophthalmol 2020 Jun 8:1120672120930590. Epub 2020 Jun 8.

Department of Ophthalmology, University of Padova, Padova, Italy.

Purpose: To describe a comprehensive OCT-based classification of myopic traction maculopathy (MTM).

Methods: Two hundred eighty-one eyes with MTM (visited from 2006 to 2018), were retrospectively reviewed for age, best-corrected-visual-acuity (BCVA), axial length (AL), optical coherence tomography (OCT), and wide-field color fundus-photographs. The study was divided in two Phases. Read More

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http://dx.doi.org/10.1177/1120672120930590DOI Listing

OCRIPLASMIN FOR VITREOMACULAR TRACTION IN CLINICAL PRACTICE: The INJECT Study.

Retina 2020 Jun 2. Epub 2020 Jun 2.

Oxurion NV, Leuven, Belgium.

Purpose: Randomized clinical trials have demonstrated the safety and efficacy of ocriplasmin in patients with vitreomacular traction (VMT), including those with macular hole (MH). The INJECT study prospectively evaluated ocriplasmin in the setting of clinical practice.

Methods: INJECT was a Phase 4, multicenter, prospective observational study. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002862DOI Listing

Contributing ocular comorbidity to end-of-life visual acuity in medically treated glaucoma patients, ocular hypertension and glaucoma suspect patients.

Eye (Lond) 2020 Jun 3. Epub 2020 Jun 3.

University Eye Clinic Maastricht, Maastricht, The Netherlands.

Aim: To assess the visual acuity at the end of life in glaucoma suspect patients, ocular hypertension, and patients treated for glaucoma and to find factors contributing to a reduced visual acuity in this cohort of deceased patients.

Methods: In a cohort of 3883 medically treated glaucoma patients, glaucoma suspect, or patients with ocular hypertension assembled in 2001-2004, 1639 were deceased. Patient data were collected from electronic and paper patient files. Read More

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http://dx.doi.org/10.1038/s41433-020-0991-0DOI Listing

Foveal crack sign: an optical coherence tomography sign preceding macular hole after vitrectomy for rhegmatogenous retinal detachment.

Am J Ophthalmol 2020 May 29. Epub 2020 May 29.

Department of Ophthalmology, Osaka Rosai Hospital Clinical Research Center for Optical Sensory Organ Disability, 1179-3, Nagasone-cho, Kita-ku, Sakai, Osaka, 591-8025, Japan.

Purpose: To describe an optical coherence tomography (OCT) sign preceding macular hole (MH) formation after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).

Design: Retrospective observational case series.

Methods: Patients who underwent PPV for RRD at Osaka Rosai Hospital between January 2014 and December 2017 were analyzed. Read More

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http://dx.doi.org/10.1016/j.ajo.2020.05.030DOI Listing

Fovea-Sparing Versus Standard Internal Limiting Membrane Peeling for Myopic Traction Maculopathy: A Study of 102 Consecutive Cases.

Ophthalmol Retina 2020 May 26. Epub 2020 May 26.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.

Purpose: To investigate the long-term outcomes of pars plana vitrectomy (PPV) with fovea-sparing internal limiting membrane (ILM) peeling (FSIP) and standard ILM peeling for myopic traction maculopathy (MTM) DESIGN: Retrospective case series SUBJECTS: One hundred and two eyes of 96 consecutive patients who underwent primary PPV for MTM and were followed up for at least 12 months.

Methods: We compared the outcomes of eyes that underwent vitrectomy with FSIP from October 2012 through March 2017 with those of eyes that underwent vitrectomy with standard ILM peeling from June 2008 through September 2012.

Main Outcome Measures: Best-corrected visual acuity (BCVA) at 12 months and at the final follow-up visit after surgery, time to MTM resolution, and postoperative complications such as macular hole (MH) formation. Read More

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http://dx.doi.org/10.1016/j.oret.2020.05.016DOI Listing

Commentary: Persistent macular hole: A long way to go.

Indian J Ophthalmol 2020 Jun;68(6):1196-1197

Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India.

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http://dx.doi.org/10.4103/ijo.IJO_181_20DOI Listing

Successful management of persistent macular hole after macular hole surgery with intravitreal triamcinolone acetonide: A case report.

Indian J Ophthalmol 2020 Jun;68(6):1193-1196

Department of Ophthalmology, Indraprastha Apollo Hospital and Center for Sight, New Delhi, India.

We present a case of persistent macular hole (MH) having an apical diameter of 140 microns and a basal diameter of 530 microns following a combined phacoemulsification and MH surgery. Considering post-operative cystoid macular edema (CME) as the possible reason for the failure of the initial surgery, a trial of IVTA was given. The synergistic effect of mechanical plugging of the hole by TA, coupled with resolution of cystoid changes and falling back of the macular hole resulted in the successful closure of the persistent macular hole with improvement in vision from 20/250 to 20/63. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1511_19DOI Listing

B-HEX pupil expander in vitreoretinal surgery - A case series.

Indian J Ophthalmol 2020 Jun;68(6):1188-1191

Disha Eye Hospitals, Kolkata, West Bengal, India.

We describe the successful use of the B-HEX pupil expansion device in four cases of combined phacovitrectomy with significant cataract, non-dilating pupil, and surgical vitreoretinal pathologies including vitreous hemorrhage, inferior retinal detachment (RD) with proliferative vitreoretinopathy in an oil filled eye, recurrent rhegmatogenous RD, and macular hole with RD localized to the posterior pole in an eye with uveitic sequelae. The B-HEX remained well engaged and maintained excellent mydriasis throughout the surgery despite wide fluctuations in intraocular pressure and anterior chamber fluidics. This is the first series describing use of B-HEX for combined phacovitrectomy due to myriad causes. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1675_19DOI Listing

Full-thickness macular hole with pigment epithelial detachment.

Indian J Ophthalmol 2020 Jun;68(6):1185

Vitreo-Retina Surgeon, Sarakshi Netralaya, Nagpur, Maharashtra, India.

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http://dx.doi.org/10.4103/ijo.IJO_1591_19DOI Listing

Autosomal recessive bestrophinopathy with macular hole.

Indian J Ophthalmol 2020 Jun;68(6):1173-1175

Depatment of Vitreo-Retina, B. W. Lions Eye Hospital, Bengaluru, Karnataka, India.

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http://dx.doi.org/10.4103/ijo.IJO_1346_19DOI Listing

The Healing Process and Functional Recovery of Neuroretina after Idiopathic Macular Hole Surgery without Internal Limiting Membrane Reversal Tamponade.

J Ophthalmol 2020 4;2020:2478943. Epub 2020 May 4.

Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin 300052, China.

Purpose: To investigate the healing process and functional recovery of neuroretina after idiopathic macular hole surgery, as well as analyzing the influencing factors.

Methods: Thirty-six eyes of 31 patients with full-thickness idiopathic macular hole (IMH) were enrolled in this retrospective study. All of them were operated using 23-gauge or 25-gauge vitrectomy with inner limiting membrane peeling and air tamponade. Read More

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http://dx.doi.org/10.1155/2020/2478943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222536PMC

Macular Hole Closure Without Endotamponade Application.

Retina 2020 May 22. Epub 2020 May 22.

Department of Ophthalmology, Chair of Ophthalmology and Optometry Heliodor Swiecicki University Hospital, Poznan University of Medical Sciences, Poznan, Poland.

Purpose: We describe an alternative vitreoretinal technique that allows for the macular hole closure without filling the vitreous cavity with gas.

Methods: A prospective interventional one-center case series from March 2019 to January 2020. The patients underwent the formation of viscoelastic-assisted temporal internal limiting membrane flap without any gas endotamponade. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002850DOI Listing

PERFLUOROCARBON LIQUID-ASSISTED INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE VERSUS INTERNAL LIMITING MEMBRANE PEELING FOR HIGHLY MYOPIC MACULAR HOLE RETINAL DETACHMENT.

Retina 2020 May 18. Epub 2020 May 18.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

Purpose: To compare the efficacy of a modified perfluorocarbon liquid-assisted inverted internal limiting membrane (ILM) flap technique with the standard ILM peeling for the treatment of macular hole retinal detachment in highly myopic eyes.

Methods: This was a retrospective, consecutive, nonrandomized comparative study. Forty-two macular hole retinal detachment eyes of 42 patients were included into either a perfluorocarbon liquid-assisted inverted ILM flap technique group (n = 22, inverted group) or standard ILM removal group (n = 20, peeling group). Read More

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http://dx.doi.org/10.1097/IAE.0000000000002853DOI Listing

Removal of foveal hard exudates by subretinal balanced salt solution injection using 38-gauge needle in diabetic patients.

Graefes Arch Clin Exp Ophthalmol 2020 May 25. Epub 2020 May 25.

Kami-iida Daiichi General Hospital, 2-70 Kamiiida Kita-machi, Nagoya, Aichi, 462-0802, Japan.

Purpose: To examine the anatomic and visual outcomes after removal of foveal hard exudates through a macular hole created by subretinal balanced salt solution (BSS) injection.

Methods: This was a retrospective, consecutive, case series. Six patients (7 eyes) underwent vitrectomy with removal of foveal hard exudates. Read More

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http://dx.doi.org/10.1007/s00417-020-04756-yDOI Listing

Inverted Internal Limiting Membrane Flap versus Internal Limiting Membrane Peeling for Macular Hole Retinal Detachment in High Myopia.

Ophthalmol Retina 2020 Apr 2. Epub 2020 Apr 2.

Department of Ophthalmology, Japanese Red Cross Otsu Hospital, Otsu, Japan.

Purpose: To compare surgical outcomes between the inverted internal limiting membrane (ILM) flap technique and ILM peeling for macular hole retinal detachment (MHRD) in eyes with high myopia.

Design: Multicenter cohort study.

Participants: We retrospectively reviewed medical records of consecutive patients treated between June 2008 and September 2018 at 7 hospitals and included 100 eyes with MHRD associated with high myopia in our study. Read More

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http://dx.doi.org/10.1016/j.oret.2020.03.021DOI Listing