- Rajko Igić
Exp Eye Res 2017 May 23. Epub 2017 May 23.
Department of Pharmacology, University of Banjaluka, 78000 Banjaluka, and Academy of Arts and Sciences, Republic of Srpska, Bosnia and Herzegovina. Electronic address:
This review offers a contemporary history of the renin-angiotensin (RAS) and kallikrein-kinin (KKS) systems with emphasis on how these complex systems affect the eye. It describes the types of communication (cross-talk) between the two systems and evaluates their potential role in the development of diabetic retinopathy, diabetic macular edema, age-related macular degeneration, glaucoma, and uveitis. In addition to detailing the important physiological actions of components of the RAS and KKS, possibilities are suggested for new therapeutic avenues in the treatment of common ocular diseases. Read More