4,361 results match your criteria Macrosomia


Prenatal imaging throughout gestation in Beckwith-Wiedemann syndrome.

Prenat Diagn 2019 Feb 19. Epub 2019 Feb 19.

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115.

Purpose: Prenatal occurrence and timing of appearance of associated features in Beckwith-Wiedemann syndrome (BWS) are unknown. We reviewed our BWS patients with serial fetal imaging and correlated these with postnatal findings.

Methods: All BWS patients with fetal US or MRI from 2000 to 2016 were reviewed to determine the presence of polyhydramnios, placentamegaly, macrosomia, macroglossia, retrognathia, omphalocele, visceromegaly, and hemihypertrophy. Read More

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http://dx.doi.org/10.1002/pd.5440DOI Listing
February 2019

Pregnancy outcomes of early detected gestational diabetes: a retrospective comparison cohort study, Qatar.

BMJ Open 2019 Feb 19;9(2):e023612. Epub 2019 Feb 19.

Department of Endocrinology, Qatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.

Objective: To compare pregnancy outcomes in patients with early versus usual gestational diabetes mellitus (GDM).

Design: A retrospective cohort study.

Settings: The Women's Hospital, Hamad Medical Corporation, Qatar. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023612DOI Listing
February 2019

Risk of adverse pregnancy outcomes by pre-pregnancy Body Mass Index among Italian population: a retrospective population-based cohort study on 27,807 deliveries.

Arch Gynecol Obstet 2019 Feb 15. Epub 2019 Feb 15.

Division of Obstetrics and Prenatal Medicine, Department of Medicine and Surgery (DIMEC) Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Purpose: To estimate the impact of increasing pre-pregnancy Body Mass Index (BMI) on the risk of adverse maternal and perinatal outcomes, in patients who delivered in an Italian tertiary care Obstetric department.

Methods: Data, related to women who delivered at Sant'Anna Hospital, Turin, between 2011 and 2015, were collected retrospectively from the hospital database. According to BMI, women were considered as normal weight, overweight, and class 1, 2 and 3 obese (WHO criteria). Read More

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http://dx.doi.org/10.1007/s00404-019-05093-0DOI Listing
February 2019
2 Reads

Induction of Labor at 39 Weeks of Gestation vs. Expectant Management for Low-Risk Nulliparous Women: A Cost-Effectiveness Analysis.

Am J Obstet Gynecol 2019 Feb 12. Epub 2019 Feb 12.

Oregon Health & Science University, Department of Obstetrics and Gynecology. Portland, OR.

Background: A large, recent multicenter trial found that induction of labor at 39 weeks for low-risk nulliparous women was not associated with an increased risk of cesarean delivery or adverse neonatal outcomes.

Objective: We sought to examine the cost-effectiveness and outcomes associated with induction of labor at 39 weeks versus expectant management for low-risk nulliparous women in the United States.

Study Design: A cost-effectiveness model using TreeAge software was designed to compare outcomes in women who were induced at 39 weeks versus expectantly managed. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.017DOI Listing
February 2019
1 Read

Pregnancy Outcomes in Women with Strictly Controlled Type 1 Diabetes Mellitus.

Indian J Endocrinol Metab 2018 Nov-Dec;22(6):798-800

Department of Obstetrics and Gynecology, Trakya University, Edirne, Turkey.

Objective: To evaluate the pregnancy outcomes in mothers with controlled Type 1 diabetes mellitus (T1DM).

Materials And Methods: Thirty seven pregnant patients with controlled T1DM were included in the study.

Results: Twenty (54%) out of 37 patients had preterm delivery (<37 weeks of gestation). Read More

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http://dx.doi.org/10.4103/ijem.IJEM_139_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330866PMC
February 2019

Effects of nutritional nursing intervention based on glycemic load for patient with gestational diabetes mellitus.

Ginekol Pol 2019 ;90(1):46-49

Department of Gynecology and Obstetrics, Yantai Hospital of Traditional Chinese Medicine, Yantai City, China.

Objectives: To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus.

Material And Methods: One hundred thirty-four patients diagnosed with gestational diabetes mellitus at our hospital were selected from March 2015 to March 2017 and randomly divided into the observation (n = 67) and control groups (n = 67). All of the patients in the observation and control groups received conventional nutritional nursing. Read More

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http://dx.doi.org/10.5603/GP.2019.0007DOI Listing
January 2019
1 Read

Maternal Dietary Patterns and Their Association with Pregnancy Outcomes.

Clin Nutr Res 2019 Jan 25;8(1):64-73. Epub 2019 Jan 25.

Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

Maternal nutritional status during pregnancy will affect the outcomes for the mother and the newborn. Maternal diet was assessed in 150 pregnant women during the first trimester of pregnancy by a 168-item food frequency questionnaire. Dietary patterns were explored by Factor analysis, and association of patterns with maternal and neonatal outcomes such as gestational diabetes mellitus (GDM), anemia and anthropometric indices were determined by analysis of variance and linear regression analysis. Read More

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http://dx.doi.org/10.7762/cnr.2019.8.1.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355947PMC
January 2019
1 Read

Trial of labor after cesarean section in risk pregnancies: a population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Science, University of Bergen, Norway.

Introduction: In most pregnancies after a cesarean section, a trial of labor is an option. The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate.

Material And Methods: In a cohort study (n=57 109), using data from the Medical Birth Registry of Norway 1989-2014, women with a second delivery after a first pregnancy cesarean section were included. Read More

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http://dx.doi.org/10.1111/aogs.13565DOI Listing
February 2019
1 Read

The Association between Advanced Maternal Age and Macrosomia: A Meta-Analysis.

Child Obes 2019 Feb 7. Epub 2019 Feb 7.

2 Medical Department, Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, China.

Purpose: The aim of our meta-analysis was to explore whether advanced maternal age (AMA) is regarded as an important risk factor for predicting macrosomia or not.

Methods: Three databases were systematically reviewed and reference lists of relevant articles were checked. Meta-analysis of published cohort studies was done comparing whether AMA was associated with macrosomia and adjusting for potential confounding factors. Read More

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https://www.liebertpub.com/doi/10.1089/chi.2018.0258
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http://dx.doi.org/10.1089/chi.2018.0258DOI Listing
February 2019
2 Reads

Maternal and Newborn Outcomes with Elective Induction of Labor at Term.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Department of Obstetrics & Gynecology, Oregon Health & Science University.

Background: A growing body of evidence supports improved or not worsened birth outcomes with non-medically indicated induction of labor at 39 weeks compared to expectant management. This evidence includes two recent randomized control trials. However, concern has been raised as to whether these studies are applicable to a broader US pregnant population. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.223DOI Listing
January 2019
1 Read

Maternal and perinatal outcomes in pregnant women with BMI >50: An international collaborative study.

PLoS One 2019 4;14(2):e0211278. Epub 2019 Feb 4.

National Perinatal Epidemiology Unit (NPEU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

Objective: To examine the association between maternal BMI>50kg/m2 during pregnancy and maternal and perinatal outcomes.

Materials And Methods: An international cohort study was conducted using data from separate national studies in the UK and Australia. Outcomes of pregnant women with BMI>50 were compared to those of pregnant women with BMI<50. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211278PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361432PMC
February 2019
2 Reads

Should HbA1C be used to screen pregnant women for undiagnosed diabetes in the first trimester? A review of the evidence.

J Public Health (Oxf) 2019 Jan 31. Epub 2019 Jan 31.

Public Health Wales NHS Trust, Cardiff, UK.

Background: Diabetes in pregnancy is associated with miscarriage, stillbirth, congenital abnormalities, macrosomia and perinatal mortality. The demographics of the population becoming pregnant has changed (more obese and older women). More women are therefore entering pregnancy with undiagnosed diabetes. Read More

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http://dx.doi.org/10.1093/pubmed/fdy229DOI Listing
January 2019
1 Read

Large for gestational age and macrosomia in pregnancies without gestational diabetes mellitus.

J Matern Fetal Neonatal Med 2019 Feb 17:1-10. Epub 2019 Feb 17.

a Department of Epidemiology and Biostatistics, School of Public Health , Anhui Medical University , Hefei , China.

Objective: This study aims to estimate the prevalence and risk factors of macrosomia and LGA (large for gestational age) in non-GDM (gestational diabetes mellitus) pregnant women in Fuyang, Anhui Province of China.

Methods: A large population-based cohort study was conducted among non-GDM pregnant women aged 18-45 years. Maternal sociodemographic data prior to pregnancy were collected using interviewer-administered standardized questionnaire. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2019.1
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http://dx.doi.org/10.1080/14767058.2019.1578746DOI Listing
February 2019
5 Reads

Single nucleotide polymorphism (SNP) based chromosomal microarray analysis provides clues and insights into disease mechanisms.

Ultrasound Obstet Gynecol 2019 Jan 28. Epub 2019 Jan 28.

Department of Genetics and Metabolic Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Background: Chromosomal microarray analysis (CMA) in pregnancy is the modality of choice for prenatal diagnosis of fetal malformations, diagnosing microdeletion/duplication syndromes. We demonstrate further utilities of CMA, by diagnosing monogenic disease, imprinting disorders and uniparental disomy (UPD).

Methods: We performed CMA using Affymetrix CytoScan array for 6995 pregnancies for all indications since November 2013 in a tertiary referral hospital. Read More

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http://dx.doi.org/10.1002/uog.20230DOI Listing
January 2019
1 Read

Diagnostic accuracy of HbA1c in detecting gestational diabetes mellitus.

J Matern Fetal Neonatal Med 2019 Feb 11:1-4. Epub 2019 Feb 11.

a Department of Obstetrics and Gynecology, Faculty of Medicine , Chulalongkorn University , Bangkok , Thailand.

Objective: To investigate the diagnostic value of glycated hemoglobin A1c (HbA1c) in detecting gestational diabetes mellitus (GDM).

Methods: Pregnant women at gestational age 24 weeks or more, who had abnormal GDM screening test, were enrolled in this prospective study. A HbA1c assessment was performed at the same time of 3-h 100 g oral glucose tolerance test (OGTT). Read More

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http://dx.doi.org/10.1080/14767058.2019.1576169DOI Listing
February 2019
3 Reads

Predictors of early initiation of breastfeeding among Zimbabwean women: secondary analysis of ZDHS 2015.

Matern Health Neonatol Perinatol 2019 15;5. Epub 2019 Jan 15.

1Lifestyle & Prevention Medicine Unit, Africa University Clinical Research Centre, Mutare, Zimbabwe.

Background: The World Health Organization recommends initiation of breastfeeding within the first hour of delivery. Early initiation is beneficial for both mother and baby. Previous Zimbabwe Demographic and Health Surveys (ZDHS) have shown reduction in early initiation of breast feeding from 68% (2005/06) to 58% (2015). Read More

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http://dx.doi.org/10.1186/s40748-018-0097-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332660PMC
January 2019

Is fasting plasma glucose in early pregnancy a better predictor of adverse obstetric outcomes than glycated haemoglobin?

Eur J Obstet Gynecol Reprod Biol 2019 Mar 9;234:79-84. Epub 2019 Jan 9.

Department of Endocrinology and Nutrition, Hospital del Mar, E-08003, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Campus del Mar, E-08003, Barcelona, Spain. Electronic address:

Objectives: To determine, in a multi-ethnic cohort, the suitability of first-trimester fasting plasma glucose and HbA1c levels in non-diabetic range to identify women without diabetes at increased pregnancy risk.

Study Design: A retrospective analysis of a prospective cohort between April 2013 and September 2015. Universal testing for fasting plasma glucose and HbA1c levels at the first antenatal blood sampling was performed and women were screened for gestational diabetes mellitus at 24-28 weeks' gestation. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2018.12.036DOI Listing
March 2019
2 Reads

Histological Features of Oral Cavity Mucous Membrane Epithelium in Six-Month-Old Experimental Animals Born with Macrosomia.

Acta Medica (Hradec Kralove) 2018 ;61(4):137-143

Institute of Physiology of the Czech Academy of Sciences, Department of Biomathematics, Czech Republic.

We examined the histological features of the mucobuccal fold of oral cavity mucous membrane from the area of the masticatory teeth roots' projection in 6-month-old Wistar Albino Glaxo rats with fetal macrosomia. The animals were divided into groups according to the body weight, the body length, and the Quetelet index at birth. A morphological study was performed using the Leica SP8 AOBS laser scanning confocal microscope and a conventional light (Axiostar, Zeiss) microscopy. Read More

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https://actamedica.lfhk.cuni.cz/61/4/0137/
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http://dx.doi.org/10.14712/18059694.2018.132DOI Listing
January 2018
3 Reads

Does gestational diabetes cause additional risk in twin pregnancy?

Twin Res Hum Genet 2019 Jan 21:1-8. Epub 2019 Jan 21.

Department of Obstetrics and Gynaecology,University of Melbourne,Melbourne,Australia.

It has been suggested that the risk of adverse perinatal outcomes in twin pregnancies is exacerbated by concomitant gestational diabetes mellitus (GDM). This study aimed to assess the risk incurred by twin pregnancy and by a diagnosis of GDM, separately, on the development of poor perinatal outcomes. A retrospective cohort study was conducted on all pregnant women at a tertiary center between 2016 and 2017. Read More

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http://dx.doi.org/10.1017/thg.2018.72DOI Listing
January 2019
4 Reads

Acute effects of air pollutants on adverse birth outcomes in Changsha, China: A population data with time-series analysis from 2015 to 2017.

Medicine (Baltimore) 2019 Jan;98(3):e14127

Hunan Province Maternal and Children Care Hospital.

Evidence for the acute effects of air pollutants on adverse birth outcomes is not yet conclusive. Furthermore, there are no investigations relating to the association between air pollutants and macrosomia. The aim of this study was to determine the relationship between air pollutants and low birth weight, preterm birth, and macrosomia in Changsha. Read More

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http://dx.doi.org/10.1097/MD.0000000000014127DOI Listing
January 2019
4 Reads
5.723 Impact Factor

Gestational Diabetes Mellitus (GDM) - Diagnosis, Treatment and Follow-Up. Guideline of the DDG and DGGG (S3 Level, AWMF Registry Number 057/008, February 2018).

Geburtshilfe Frauenheilkd 2018 Dec 14;78(12):1219-1231. Epub 2018 Dec 14.

Gynäkologie und Geburtshilfe, Universität Wien, Wien, Austria.

A team of experts from the fields of gynaecology and obstetrics, diabetology, internal medicine, paediatrics and midwifery from Germany, Austria and Switzerland produced a new version of the existing S3 guideline on gestational diabetes. It replaces the recommendations of the German Association for Gynaecology and Obstetrics and the German Diabetes Association on the diagnosis and treatment of gestational diabetes from 2011 and is valid for the three German-speaking countries. The primary aim of the guideline is to improve and standardise the prevention, screening, diagnosis, treatment and follow-up of gestational diabetes through evidence-based recommendations for the outpatient and inpatient area. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0659-2596
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http://dx.doi.org/10.1055/a-0659-2596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301211PMC
December 2018
6 Reads

Outcomes of type 1 diabetes mellitus in pregnancy; effect of excessive gestational weight gain and hyperglycaemia on fetal growth.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):84-88. Epub 2018 Aug 28.

Qatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.

Aims: To study pregnancy outcomes in patients with type 1 diabetes mellitus (T1DM) and the factors associated with poor outcomes.

Methods: A retrospective study of 110 patients with T2DM who attended our diabetes in pregnancy clinic at the Women's Wellness and Research centre, Doha, between March 2015 and December 2016 and 1419 normoglycaemic controls.

Results: There was no difference in age, weight, and BMI between the two groups. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.08.030DOI Listing
August 2018
1 Read

Body mass index growth trajectories from birth through 24 months in Iranian infants of mothers with gestational diabetes mellitus.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):408-412. Epub 2018 Oct 12.

Student Research Committee, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address:

Aims: Child growth is one of the important health indicators in pediatric care. Few studies focused on the impact of prenatal exposure to gestational diabetes mellitus (GDM) on growth trajectories particular in early years of childhood. The aim of this study was identifying growth pattern of GDM exposed offspring's, comparison with new WHO child growth standards. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.10.002DOI Listing
October 2018
1 Read

[Vaginal birth after previous cesarean section in low-resource countries: healthcare chain and materno-fetal follow-up].

Pan Afr Med J 2018 6;30:255. Epub 2018 Aug 6.

Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.

The rate of uterine scars, an established risk factor for obstetric morbidity, is increasing worldwide. In developing countries, spontaneous uterine ruptures may constitute 87.4% of cases. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.255.15678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317296PMC
January 2019
1 Read

Association between fetal macrosomia and risk of obesity in children under 3 years in Western China: a cohort study.

World J Pediatr 2019 Jan 11. Epub 2019 Jan 11.

Chinese Evidence-based Medicine Center, Center for Clinical Epidemiology and Evidence-based Medicine, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu, 610041, Sichuan, China.

Background: Fetal macrosomia, defined as birth weight equal or over 4000 g, is a major concern for both neonatal and maternal health. A rapid increasing trend in fetal macrosomia is observed in different regions of China. We aimed to examine the association between fetal macrosomia and risk of childhood obesity in Western China. Read More

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http://dx.doi.org/10.1007/s12519-018-0218-7DOI Listing
January 2019
2 Reads

Gestational diabetes mellitus in underweight women.

J Matern Fetal Neonatal Med 2019 Jan 27:1-3. Epub 2019 Jan 27.

a Department of Perinatology, Division of Obstetrics and Gynecology , University Medical Centre Ljubljana , Ljubljana , Slovenia.

Objective: To compare outcomes of pregnancies complicated by gestational diabetes mellitus (GDM) in underweight women with those of normal pregravid BMI.

Methods: We used a population-based dataset to identify singleton pregnancies complicated by GDM in underweight and normal weight women.

Results: Among women with GDM, we identified 301 and 6494 women with pregravid underweight and normal BMI. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2019.1
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http://dx.doi.org/10.1080/14767058.2019.1568979DOI Listing
January 2019
1 Read

Incidence and risk factors for postpartum hemorrhage among transvaginal deliveries at a tertiary perinatal medical facility in Japan.

PLoS One 2019 9;14(1):e0208873. Epub 2019 Jan 9.

Department of Obstetrics and Gynecology, ASO Iizuka Hospital, Iizuka, Fukuoka, Japan.

Postpartum hemorrhage (PPH) remains a leading cause of maternal death worldwide, and it is important to understand the relative contributions of different risk factors. We assessed the incidence of these among cases of transvaginal delivery. Between June 2013 and July 2016, a prospective cohort study was conducted at a tertiary perinatal medical facility in Japan. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208873PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326562PMC
January 2019
3 Reads

An observational study of the risk of neonatal macrosomia, and early gestational diabetes associated with selected candidate genes for type 2 diabetes mellitus polymorphisms in women with gestational diabetes mellitus.

Ginekol Pol 2018 ;89(12):705-710

Department of Reproduction, Karol Marcinkowski University of Medical Sciences, Poznan, Poland.

Objectives: 1) to analyse the prevalence of selected candidate genes for type 2 diabetes mellitus polymorphisms (IRS1 G972R; ENPP1 K121Q; ADRB3 W64R) among women with gestational diabetes; and 2) to investigate any association between variants of these genes and risk of neonatal macrosomia.

Material And Methods: We conducted a prospective observational study of a group of women (N = 140) in singleton pregnancies who delivered at term. Characteristics of the study group at enrolment: age: 32. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0119DOI Listing
January 2018
5 Reads

Gestational diabetes: weight gain during pregnancy and its relationship to pregnancy outcomes.

Chin Med J (Engl) 2019 Jan;132(2):154-160

Department of Clinical Nutrition, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

Background: Weight gain during pregnancy reflects the mother's nutritional status. However, it may be affected by nutritional therapy and exercise interventions used to control blood sugar in gestational diabetes mellitus (GDM). This study aimed to evaluate weight gain during gestation and pregnancy outcomes among women with GDM. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000036DOI Listing
January 2019
3 Reads

Fetal growth trajectories and their association with maternal and child characteristics.

J Matern Fetal Neonatal Med 2019 Jan 6:1-7. Epub 2019 Jan 6.

a UCD Perinatal Research Centre, National Maternity Hospital , Dublin , Ireland.

Background: The growth of the fetus is a complex process, influenced by genetic and environmental factors. Longitudinal patterns of fetal growth are required to fully understand this process, however to date, a paucity of data exists in this area.

Objective: To identify fetal growth trajectories in-utero and to assess their association with maternal and child characteristics up to 5 years postnatal. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2018.1
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http://dx.doi.org/10.1080/14767058.2018.1554041DOI Listing
January 2019
6 Reads

Advanced cervical dilatation as a predictor for low emergency cesarean delivery: a comparison between migrant and non-migrant Primiparae - secondary analysis in Berlin, Germany.

BMC Pregnancy Childbirth 2019 Jan 3;19(1). Epub 2019 Jan 3.

School of Public Health, Department of Epidemiology & International Public Health, Bielefeld University, Bielefeld, Germany.

Background: Cesarean rates are higher in women admitted to labor ward during early stages rather than at later stages of labor. In a study in Germany, crude cesarean rates among Turkish and Lebanese immigrant women were low compared to non-immigrant women. We evaluated whether these immigrant women were admitted during later stages of labor, and if so, whether this explains their lower cesarean rates. Read More

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http://dx.doi.org/10.1186/s12884-018-2145-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318868PMC
January 2019
3 Reads

Prenatal Exercise and Pre-gestational Diseases: A Systematic Review and Meta-analysis.

J Obstet Gynaecol Can 2018 Dec 28. Epub 2018 Dec 28.

Program for Pregnancy and Postpartum Health, Physical Activity and Diabetes Laboratory, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, AB; Women and Children's Health Research Institute, University of Alberta, Edmonton, AB; Alberta Diabetes Institute, University of Alberta, Edmonton, AB. Electronic address:

Objective: This study sought to examine the effect of prenatal exercise on birth outcomes in women with pre-gestational diseases, including chronic hypertension, type 1 diabetes, and type 2 diabetes.

Methods: A structured search of online databases up to June 8, 2018 was conducted. Studies of all designs and languages were included if they contained information on the population (pregnant women with pre-gestational diseases), intervention (subjective or objective measures of frequency, intensity, duration, volume, or type of exercise), comparator (no exercise or different frequency, intensity, duration, volume, or type of exercise), and outcome (birth weight, macrosomia [birth weight >4000 g], large for gestational age (LGA) low birth weight [<2500 g], small for gestational age (SGA) [<10th percentile], Apgar score, preterm birth [<37 weeks], CS, preeclampsia, and glycemic control). Read More

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http://dx.doi.org/10.1016/j.jogc.2018.10.007DOI Listing
December 2018
3 Reads

Transferred maternal fatty acids stimulate fetal adipogenesis and lead to neonatal and adult obesity.

Authors:
Andrew J Szabo

Med Hypotheses 2019 Jan 22;122:82-88. Epub 2018 Oct 22.

Lenox Hill Hospital, Division of Endocrinology and Metabolism, 100 East 77-th Street, New York, NY 10075, USA. Electronic address:

The prevalence of adult and childhood obesity are increasing. Most of the human newborn's body fat accumulates in the last half of intrauterine life. Fat in the fetus was thought to be mostly synthesized from glucose, but now it is commonly accepted that the bulk of it is the product of placental transfer of maternal fatty acids. Read More

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http://dx.doi.org/10.1016/j.mehy.2018.10.022DOI Listing
January 2019
2 Reads

Detection and initial management of gestational diabetes through primary health care services in Morocco: An effectiveness-implementation trial.

PLoS One 2018 28;13(12):e0209322. Epub 2018 Dec 28.

Institute of Tropical Medicine, Antwerp, Belgium.

Background: Gestational Diabetes Mellitus (GDM) testing and management in Morocco is associated with delays resulting in late commencement of treatment. To reduce delays and to increase access of women to GDM care, a country-adapted intervention targeting primary health care providers was designed to test the hypothesis that detection and initial management of GDM at the primary level of care improves newborn outcomes in terms of lower birthweights and less cases of macrosomia and impacts on maternal weight gain, glucose balance and pregnancy outcomes.

Materials And Methods: We conducted a cluster randomized controlled trial in two districts of Morocco. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209322PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310282PMC
December 2018
1 Read
3.234 Impact Factor

Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome.

BMC Pregnancy Childbirth 2018 Dec 27;18(1):507. Epub 2018 Dec 27.

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Bariatric surgery (BS) is regarded to be the most effective treatment of obesity with long lasting beneficial effects including weight loss and improvement of metabolic disorders. A considerable number of women undergoing BS are at childbearing age.Although the surgery mediated weight loss has a positive effect on pregnancy outcome, the procedures might be associated with adverse outcomes as well, for example micronutrient deficiencies, iron or B12 deficiency anemia, dumping syndrome, surgical complications such as internal hernias, and small for gestational age (SGA) offspring, possibly due to maternal undernutrition. Read More

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http://dx.doi.org/10.1186/s12884-018-2124-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307154PMC
December 2018
2 Reads

Can Nurse-Based Management Screening Ensure Adequate Outcomes in Patients With Gestational Diabetes? A Comparison of 2 Organizational Models.

Qual Manag Health Care 2019 Jan/Mar;28(1):51-62

Endocrinological, Metabolic and Nutrition Unit, Department of Specialized Medicine, Local Health Authority (ULSS 2), Treviso, Italy (Drs Nollino, Kiwanuka, Sambataro, Sambado, Trevisiol, and Paccagnella and Mss Marcon, Merlotto-Cazziola, and Scantamburlo); Inpatient Psychological Service, Local Health Authority (ULSS 2), Treviso, Italy (Mss Mauri and Migot); Obstetrics and Gynecology Unit, Maternal Department, Local Health Authority (ULSS 2), Treviso, Italy (Dr Busato); Local Pharmacy Service, Local Health Authority (ULSS 2), Treviso, Italy (Drs Trevisiol and Pirolo); Internal Medicine Unit, Department of Medicine, Local Health Authority (ULSS 1), Belluno, Italy (Dr Boaretto); Medical Genetics Unit, Local Health Authority (ULSS 2), Treviso, Italy (Dr Turolla); and General Management, Local Health Authority (ULSS 2), Treviso, Italy (Mr Faronato and Dr Cadamuro-Morgante).

Background: Gestational diabetes mellitus (GDM) is an impaired glucose tolerance with onset or first recognition during pregnancy. The purpose of this study is to evaluate the clinical outcomes of a blood glucose monitoring protocol implemented by nurses and dietitians in a diabetes team to the previously established protocol of direct monitoring of GDM patients by a diabetologist.

Methods: Two groups of patients were formed: The first group was based on a traditional protocol (P1: 230 patients) with patients' blood glucose constantly checked by a diabetologist. Read More

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http://dx.doi.org/10.1097/QMH.0000000000000202DOI Listing
December 2018
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Predictors of drug use during pregnancy: The relative effects of socioeconomic, demographic, and mental health risk factors.

J Neonatal Perinatal Med 2018 Dec 21. Epub 2018 Dec 21.

Department of Epidemiology & Biostatistics, Western University, London, ON, Canada.

Background: With limited Canadian research on predictors of drug use during pregnancy, the primary objective was to assess the relative effects of socioeconomic, demographic, and mental health risk factors associated with drug use during pregnancy. Predictors of an Apgar score <  7 and fetal macrosomia were examined as secondary outcomes.

Methods: This retrospective cohort study consisted of 25,734 pregnant women from Southwestern Ontario. Read More

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http://dx.doi.org/10.3233/NPM-1814DOI Listing
December 2018
2 Reads

Recent Lifestyle Parameters Are Associated with Increasing Caesarean Section Rates among Singleton Term Births in Austria.

Int J Environ Res Public Health 2018 Dec 21;16(1). Epub 2018 Dec 21.

Clinic for Gynaecology and Obstetrics, Danube Hospital, A-1220 Vienna, Austria.

Caesarean section (CS) rates are increasing in many parts of the world, recently reaching about 20% worldwide. The postmodern lifestyle characteristics, obesity and delayed childbirth, have been put forward as the main reasons for high CS rates. The present study tests the association patterns between lifestyle parameters and delivery mode on a data set of 3786 births in Vienna between 2005 and 2013. Read More

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http://dx.doi.org/10.3390/ijerph16010014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338883PMC
December 2018
1 Read

Type 2 diabetes mellitus in pregnancy: The impact of maternal weight and early glycaemic control on outcomes.

Eur J Obstet Gynecol Reprod Biol 2019 Feb 13;233:53-57. Epub 2018 Dec 13.

Qatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.

Objectives: To study the pregnancy outcomes in women with type 2 diabetes mellitus (T2DM) and to relate these to maternal risk factors.

Methods: We conducted a retrospective study of 419 women with T2DM (index group)- who attended our diabetes in pregnancy clinic at the Hamad Women's Hospital, Doha, between March 2015 and December 2016 -and 1419 normoglycaemic women (control group).

Results: Compared with the controls, T2DM women were older (mean age 34. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03012115183113
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http://dx.doi.org/10.1016/j.ejogrb.2018.12.008DOI Listing
February 2019
9 Reads

Does prenatal identification of fetal macrosomia change management and outcome?

Arch Gynecol Obstet 2018 Dec 18. Epub 2018 Dec 18.

Department of Obstetrics and Gynecology, Rambam Health Care Campus, Bnai-Zion Medical Center, Haifa, Israel Affiliated to the Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Purpose: To assess whether there is an association between predicted fetal macrosomia and adverse outcomes in macrosomic newborns (> 4000 g), based on a sonographic evaluation up to 2 weeks prior to delivery.

Methods: A retrospective cohort study of 3098 mothers of macrosomic babies who were delivered at our institution (2000-2015). We compared the management and outcomes of women with predicted fetal macrosomia with that of women with unknown fetal macrosomia. Read More

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http://dx.doi.org/10.1007/s00404-018-5003-2DOI Listing
December 2018
1 Read

The influence of different inositol stereoisomers supplementation in pregnancy on maternal gestational diabetes mellitus and fetal outcomes in high-risk patients: a randomized controlled trial.

J Matern Fetal Neonatal Med 2018 Dec 17:1-9. Epub 2018 Dec 17.

a Department of Obstetrics and Gynaecology , University of Chieti , Chieti , Italy.

Objective: To identify the effects of different dietary inositol stereoisomers on insulin resistance and the development of gestational diabetes mellitus (GDM) in women at high risk for this disorder.

Design: A preliminary, prospective, randomized, placebo controlled clinical trial.

Participants: Nonobese singleton pregnant women with an elevated fasting glucose in the first or early second trimester were studied throughout pregnancy. Read More

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http://dx.doi.org/10.1080/14767058.2018.1500545DOI Listing
December 2018
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Association between prophylactic low-molecular-weight heparin use in pregnancy and macrosomia: analysis of the Ottawa and Kingston birth cohort.

J Thromb Haemost 2019 Feb 8;17(2):345-349. Epub 2019 Jan 8.

OMNI Research Group, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Essentials Low-molecular-weight heparin (LMWH) is used to prevent venous thromboembolism (VTE) in pregnancy. We evaluated the association between LMWH and large for gestational age (LGA) infants. We found no significant associations between LMWH use and LGA. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jth.14358
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http://dx.doi.org/10.1111/jth.14358DOI Listing
February 2019
9 Reads

Excessive Gestational Weight Gain.

J Midwifery Womens Health 2019 Jan 12;64(1):46-54. Epub 2018 Dec 12.

Excessive gestational weight gain (GWG) is associated with an increasing incidence of maternal and neonatal complications, including hypertensive disorders of pregnancy, fetal macrosomia, and increased cesarean birth rates. In the United States, it is recommended that health care providers use an individualized approach to counsel a woman about pregnancy weight gain goals that is based on the woman's initial body mass index (BMI) and to track GWG throughout the pregnancy by evaluating maternal weight at each visit. Studies have shown that women entering pregnancy with a higher BMI are at increased risk for excessive GWG and postpartum weight retention. Read More

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http://dx.doi.org/10.1111/jmwh.12927DOI Listing
January 2019
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Obstetric and perinatal outcomes of singleton pregnancies conceived via assisted reproductive technology complicated by gestational diabetes mellitus: a prospective cohort study.

BMC Pregnancy Childbirth 2018 Dec 14;18(1):495. Epub 2018 Dec 14.

Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Firouzeh St., South Vali- Asr Ave., Vali- Asr Sq., Tehran, 15937-16615, Iran.

Background: Growing evidence indicates that the risk of obstetric and perinatal outcomes is higher in women with assisted reproductive technology (ART). However, there is little known about pregnancy related complications and co-morbidity in gestational diabetes mellitus (GDM) following singleton pregnancies achieved by ART in comparison with spontaneous conception (SC).

Methods: Two hundred sixty singleton pregnant women conceived by ART and 314 pregnant women conceived by spontaneous conception (SC) were participated in this prospective cohort study. Read More

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https://bmcpregnancychildbirth.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12884-018-2115-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295020PMC
December 2018
12 Reads

Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis.

BMC Pregnancy Childbirth 2018 Dec 14;18(1):494. Epub 2018 Dec 14.

Department of Pharmacy Practice, School of Pharmacy, International Medical University, 57000, Kuala Lumpur, Malaysia.

Background: Gestational diabetes mellitus (GDM) is a of the major public health issues in Asia. The present study aimed to determine the prevalence of, and risk factors for GDM in Asia via a systematic review and meta-analysis.

Methods: We systematically searched PubMed, Ovid, Scopus and ScienceDirect for observational studies in Asia from inception to August 2017. Read More

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http://dx.doi.org/10.1186/s12884-018-2131-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295048PMC
December 2018
3 Reads

Magnitude of fetal macrosomia and its associated factors at public health institutions of Hawassa city, southern Ethiopia.

BMC Res Notes 2018 Dec 13;11(1):888. Epub 2018 Dec 13.

School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Objectives: This study aimed to determine the magnitude of fetal macrosomia and associated factors at public health institutions of Hawassa city, southern Ethiopia.

Results: In this study, the magnitude of fetal macrosomia found to be 11.86%. Read More

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https://bmcresnotes.biomedcentral.com/articles/10.1186/s1310
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http://dx.doi.org/10.1186/s13104-018-4005-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293502PMC
December 2018
10 Reads

Management and pregnancy outcomes of women with GCK-MODY enrolled in the US Monogenic Diabetes Registry.

Acta Diabetol 2018 Dec 11. Epub 2018 Dec 11.

Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Kovler Diabetes Center, University of Chicago, 5841 South Maryland Ave., MC 1027, Chicago, IL, 60637, USA.

Aims: GCK-MODY is characterized by mild hyperglycemia. Treatment is not required outside of pregnancy. During pregnancy, insulin treatment is recommended if second trimester fetal ultrasound monitoring shows macrosomia, suggesting the fetus has not inherited the GCK gene. Read More

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http://dx.doi.org/10.1007/s00592-018-1267-zDOI Listing
December 2018
4 Reads

Associations of serum markers screening for Down's syndrome with pregnancy outcomes: A Chinese retrospective cohort study.

Clin Chim Acta 2019 Feb 6;489:130-135. Epub 2018 Dec 6.

Department of Obstetrics and Gynecology, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, No. 16 Bo Ai Road, Changzhou, Jiangsu Province, China. Electronic address:

Background: We examined the associations between Down's serum screening analytes and pregnancy outcomes in Chinese women.

Methods: A retrospective cohort study of 2470 pregnant women was conducted. Maternal serum triple tests (AFP, fβ-hCG, uE3), maternal characteristics and pregnancy outcomes were recorded from our prenatal screening and hospitalization information system, respectively. Read More

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http://dx.doi.org/10.1016/j.cca.2018.12.001DOI Listing
February 2019
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Childhood health and education outcomes following early term induction for large-for-gestational age: A population-based record linkage study.

Acta Obstet Gynecol Scand 2018 Dec 4. Epub 2018 Dec 4.

Clinical and Population Perinatal Health Research, Northern Sydney Local Health District, Kolling Institute, Sydney, NSW, Australia.

Introduction: There is debate about optimal management of pregnancies with a large-for-gestational age baby. A recent randomized controlled trial reported that early term induction of labor reduced cesarean section rates and infant morbidity. However, long term childhood outcomes have not been assessed. Read More

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http://dx.doi.org/10.1111/aogs.13511DOI Listing
December 2018
3 Reads

Early Pregnancy Hemoglobin A1C and Pregnancy Outcomes: A Population-Based Study.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Kaiser Permanente Washington Health Research Institute, Seattle, Washington.

Objectives:  Women with prediabetes are identified from screening for overt diabetes in early pregnancy, but the clinical significance of prediabetes in pregnancy is unclear. We examined whether prediabetes in early pregnancy was associated with risks of adverse outcomes.

Study Design:  We conducted a retrospective cohort study of pregnant women enrolled in Kaiser Permanente Washington from 2011 to 2014. Read More

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http://dx.doi.org/10.1055/s-0038-1675619DOI Listing
November 2018
2 Reads