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Rom J Ophthalmol 2021 Jan-Mar;65(1):70-72

Smt. Kanuri Santhamma Centre for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad India.

A 53-year-old lady presented with inferior retinal detachment (RD) following focal laser for retinal artery macroaneurysm (RAM). She underwent focal laser with intravitreal gas injection elsewhere; however, no retinal break was localized on the examination. The patient was taken up for vitreoretinal surgery. Read More

Middle East Afr J Ophthalmol 2020 Oct-Dec;27(4):228-230. Epub 2021 Jan 19.

Department of Ophthalmology, College of Medicine, King Saud University, Jeddah, Saudi Arabia.

Retinal arterial macroaneurysm with supravalvular pulmonic stenosis (RAMSVPS), also known as familial retinal arterial macroaneurysm syndrome, is an autosomal recessive disorder associated with many life-threatening complications. The disease is characterized by progressive multiple retinal arterial macroaneurysms, retinal arterial beading, and recurrent vitreous hemorrhage. Here, we describe the first case of RAMSVPS associated with peripheral ischemia evident on ultra-widefield fluorescein angiography. Read More

Am J Ophthalmol Case Rep 2021 Jun 5;22:101053. Epub 2021 Mar 5.

Department of Ophthalmology, Hirosaki University Graduate School of Medicine, 5 Zaifu, Hirosaki, Aomori, Japan.

Purpose: To describe a rare case of racemose hemangioma which developed spontaneous macular macroaneurysm (MA) rupture and vitreaous hemorrhage.

Observations: A 29-year-old healthy asian female visited our hospital and a racemose hemangioma was found in the left eye. At presentation, the best corrected visual acuity (BCVA) was 30/20 in her left eye. Read More

Am J Ophthalmol Case Rep 2021 Mar 2;21:101022. Epub 2021 Feb 2.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan.

Purpose: To report the changes over time in ocular blood flow quantified by laser speckle flowgraphy (LSFG) in a treated large retinal arterial macroaneurysm (RAM).

Observations: A 72-year old female presented with sudden decreased vision in the left eye. Fundus examination revealed a RAM and vitreous hemorrhage (VH), which worsened over one month. Read More

Eur J Ophthalmol 2021 Feb 8:1120672121993781. Epub 2021 Feb 8.

Department of Neonatology, University of Health Sciences Dr. Behcet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Izmir, Turkey.

Introduction: Retinal arterial macroaneurysm (RAM) is an acquired vascular dilatation usually seen at the site of arterial bifurcation or arterial-vein crossing. It's often seen in the first three branches of the central retinal artery.

Case Description: A 15-year-old male patient was admitted to the outpatient clinic with complaints of weakness, headache, and bruising on the body for a few weeks. Read More

Asia Pac J Ophthalmol (Phila) 2021 Jan-Feb 01;10(1):129

Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Ophthalmol Retina 2021 01;5(1):96

Department of Ophthalmology, The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province, People's Republic of China.

Retina 2021 Feb;41(2):e15-e16

Ocular Oncology Service, Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

J Fr Ophtalmol 2021 Feb 10;44(2):e91-e95. Epub 2020 Dec 10.

Khzema Ouest, Sousse, Tunisie, 4072 Sousse, Tunisie.

Ophthalmol Retina 2020 Dec;4(12):1180

Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

SAGE Open Med Case Rep 2020 13;8:2050313X20970337. Epub 2020 Nov 13.

Ophthalmology Department, Newcastle upon Tyne, UK.

The objective of this case series is the evaluation of the efficacy and visual outcomes after displacement of subretinal hemorrhage using intravitreal injection of recombinant tissue plasminogen activator, expansile gas, and in some cases an anti-vascular endothelial growth factor agent. A case series of 28 eyes of 28 patients (16 men and 12 women with age range 67-95 years) suffering from subretinal hemorrhage (duration range 1-15 days) caused by age-related macular degeneration or retinal macroaneurysm is presented. All the patients were treated with intravitreal injection of recombinant tissue plasminogen activator and gas and some of them received an anti-vascular endothelial growth factor agent between January 2013 and December 2016. Read More

Tidsskr Nor Laegeforen 2020 11 23;140(17). Epub 2020 Nov 23.

J Fr Ophtalmol 2021 Mar 12;44(3):465-466. Epub 2020 Nov 12.

Institut Català de Retina, Carrer de Ganduxer, 117, 08022 Barcelona, Spain.

Can J Ophthalmol 2020 Oct 14. Epub 2020 Oct 14.

Instituto de Olhos Ciências Médicas, Belo Horizonte/Minas Gerais, Brazil.

Retina 2021 Apr;41(4):890-894

Department of Ocular Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.

Purpose: To report a case of vitreous seeding in a medium-sized choroidal melanoma and review the literature.

Methods: Observational case report and review of literature for pathogenesis, role of vitreous biopsy, and treatment outcomes.

Results: A case of 57-year-old man diagnosed with vitreous seeding in the left eye 1 year after episcleral brachytherapy for medium-sized choroidal melanoma. Read More

GMS Ophthalmol Cases 2020 6;10:Doc31. Epub 2020 Aug 6.

Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

To present a 65-year-old patient with macular hole (MH) and submacular hemorrhage (SMH) secondary to a ruptured retinal arterial macroaneurysm (RAM) which was successfully treated with a novel surgical technique. A 65-year-old woman presented with a 1-week history of sudden-onset visual loss in her right eye. Her best-corrected visual acuity (BCVA) was hand motion in the right eye. Read More

Oman J Ophthalmol 2020 May-Aug;13(2):102-103. Epub 2020 May 28.

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

We report a case of a young male with symptomatic isolated venous macro-aneurysm without any associated systemic disease. Multi modal imaging was useful in making the correct diagnosis. To the best of our knowledge, primary isolated venous macro-aneurysm has not been reported previously. Read More

Ophthalmic Surg Lasers Imaging Retina 2020 06;51(6):365-366

A 34-year-old Caucasian woman with a past medical history of hypertension presented with acute floaters in the right eye (OD) for 1 week. Best-corrected visual acuity (VA) was 20/20 in both eyes. Fundus examination OD (Figure 1) revealed a retinal hemangioblastoma (RH) in the temporal midperiphery with a prominent feeding artery and draining vein. Read More

Arch Soc Esp Oftalmol 2020 Oct 17;95(10):e78. Epub 2020 Jun 17.

Servicio de Oftalmología, Hospital Universitario Fundación de Alcorcón, Alcorcón, Madrid, España.

Arch Soc Esp Oftalmol 2021 Mar 5;96(3):162-166. Epub 2020 Jun 5.

Servicio de Oftalmología, Sección de Retina, Hospital Universitario de Canarias, Santa Cruz de Tenerife, España.

We present a case of a woman with idiopathic macular telangiectasia type 1, characterized by the presence of a capillary macroanaeurysm associated with macular edema with a macular star pattern. Several differential diagnoses were proposed, in which the study with a multimodal image was key to clarify the diagnosis. In addition, the various treatments used and their effectiveness are discussed. Read More

Ophthalmol Retina 2020 06;4(6):629

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan; Chang Gung University College of Medicine, Taoyuan, Taiwan.

Korean J Ophthalmol 2020 06;34(3):259-261

Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Clin Exp Optom 2021 Mar;104(2):250-252

Department of Ophthalmology, Sydney Eye Hospital, Sydney, Australia.

Ophthalmic Genet 2020 08 19;41(4):394-396. Epub 2020 May 19.

Vitreoretinal Division, King Khaled Eye Specialist Hospital , Riyadh, Saudi Arabia.

Purpose: To report a favorable effect of intravitreal dexamethasone implantation in Familial Retinal Arterial Macroaneurysms (FRAM).

Methods: Retrospective Case Report.

Results: A 32-year-old male who presented with bilateral retinal macroaneurysms. Read More

Tunis Med 2020 Jan;98(1):80-84

A 45 years old patient consulted for a sudden decrease in visual acuity in the right eye. Ophthalmological examination gave visual acuity limited to luminous perceptions with a calm anterior segment, a transparent lens and at the fundus examination a dense, massive, two-level intra-retinal and retro hyaloidal pigeon nest hemorrhage with a fusiform whitish lesion on the path of the upper temporal artery. The suspected diagnosis was a complicated ruptured retinal macroaneurysm with massive retinal and retro hyaloidal hemorrhage. Read More

Am J Case Rep 2020 May 9;21:e922437. Epub 2020 May 9.

Eye Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.

BACKGROUND We report the successful treatment of a macular hole (MH) secondary to a retinal macroaneurysm (RAMA) rupture by pars plana vitrectomy (PPV) and autologous transplantation of an internal limiting membrane (ILM) during primary surgery. CASE REPORT A 60-year-old woman presented with a sudden loss of central vision in her right eye. Fundus examination revealed a large sub-ILM hemorrhage involving the macula in her right eye. Read More

Am J Ophthalmol 2020 10 28;218:59-67. Epub 2020 Apr 28.

Division of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

Purpose: To describe the pre-exudative stage of exudative perifoveal vascular anomalous complex (ePVAC), referred to as nonexudative PVAC (nePVAC).

Design: Retrospective noncomparative case series.

Methods: Patients diagnosed with nePVAC were identified at 4 retina referral centers worldwide. Read More

Medwave 2020 Mar 3;20(2):e7831. Epub 2020 Mar 3.

Instituto Mexicano de Oftalmología I.A.P, Querétaro, México. Universidad Nacional Autónoma de México, CDMX, México.

Introduction: Macular hemorrhages result in a sudden and profound loss of vision. The primary treatment modalities include observation, intravitreal injection of antiangiogenic drugs, neodymium-doped yttrium aluminum garnet hialoidotomy, intravitreal injection of gas with or without tissue plasminogen activator, as monotherapy or combined with surgery. In this paper, we report four cases of macular hemorrhages of different causes treated with different approaches, and we review the literature in this regard. Read More

BMJ Open Ophthalmol 2020 16;5(1):e000394. Epub 2020 Mar 16.

New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.

Objective: Fovea-involving subretinal haemorrhage is challenging to manage with uncertain visual outcomes. We reviewed outcomes of patients with fovea-involving macular haemorrhage treated with pars plana vitrectomy (PPV) and subretinal tissue plasminogen activator (tPA) with pneumatic displacement.

Methods And Analysis: This is a retrospective interventional case series. Read More