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Jpn J Ophthalmol 2019 Mar 19;63(2):186-196. Epub 2019 Feb 19.

Department of Ophthalmology, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan.

Purpose: To investigate the usefulness of anatomic site-oriented therapy for macular hemorrhage secondary to retinal arterial macroaneurysm (RAM).

Study Design: Retrospective observational study, clinical case series METHODS: Twenty-seven consecutive patients (27 eyes) with macular hemorrhage secondary to RAM were classified according to the retinal layer(s) with hemorrhage identified by optical coherence tomography into 4 types and treated differentially. Vitrectomy was conducted for subinternal limiting membrane hemorrhage (SILMH), intravitreal gas injection for subretinal hemorrhage (SRH) or intraretinal hemorrhage (IRH), and vitrectomy and intravitreal air/gas exchange for multilevel hemorrhage (at least 2 among SILMH/SRH/IRH). Read More

Retina 2019 Jan 14. Epub 2019 Jan 14.

Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan.

Purpose: To investigate the clinical course of submacular hemorrhage associated with ruptured retinal arterial macroaneurysm using swept-source optical coherence tomography.

Methods: This study included 23 eyes of 23 consecutive patients diagnosed with submacular hemorrhage associated with ruptured retinal arterial macroaneurysm. Cases underwent displacement of submacular hemorrhage (vitrectomy + subretinal injection of tissue plasminogen activator + air tamponade) and were followed up for 6 months after surgery. Read More

BMC Ophthalmol 2019 Jan 15;19(1):18. Epub 2019 Jan 15.

Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.

Background: There is no consensus for the standard treatment of retinal arterial macroaneurysm (RAM). Intravitreal anti-vascular endothelium growth factor (anti-VEGF) is an alternative treatment option for RAM. The purpose of this study is to describe the clinical efficacy of intravitreal ranibizumab or intravitreal conbercept for retinal arterial macroaneurysm. Read More

Ophthalmol Retina 2018 Jul 15;2(7):694-702. Epub 2017 Dec 15.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

Objective: To characterize features of extra-vascular optical coherence tomography angiography (OCTA) signals corresponding to hyperreflective intraretinal fluid across various exudative maculopathies.

Design: Multicenter, retrospective, observational study.

Participants: Eyes with various forms of exudative maculopathy including diabetic retinopathy (DR), retinal vein occlusion (RVO), and neovascular-age related macular degeneration (nvAMD). Read More

Int J Retina Vitreous 2018 22;4:28. Epub 2018 Aug 22.

2Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India.

Objectives: To compare the efficacy and safety of conventional and navigated laser photocoagulation as the primary treatment option for retinal arteriolar macroaneurysm (RAM).

Methods: Eleven (9 male and 2 females, mean age 65.1 ± 12. Read More

Indian J Ophthalmol 2018 09;66(9):1352-1354

Department of Vitreoretina and Ocular Oncology, Sankara Eye Hospital, Bengaluru, Karnataka, India.

We present a rare case of retinal racemose angioma complicated with fleeting macroaneurysm (MA). A 50-year-old female presented with diminution of vision in her right eye for 6 years. Fundus examination showed a racemose angioma with hemorrhagic MA temporal to the fovea in the right eye. Read More

Medicine (Baltimore) 2018 Jul;97(30):e11497

Department of Ophthalmology, China-Japan Union Hospital of Jilin University, Changchun.

Rationale: Neurofibromatosis type I (NF-1) is a multisystem autosomal dominant disease characterized by pigmentation and the growth of tumors along nerves in the skin, brain, and other parts of the body. It is caused by a mutation in the NF-1 tumor suppressor gene. NF-1 vascular disease is an important complication of the disease. Read More

Lasers Med Sci 2019 Mar 19;34(2):427-430. Epub 2018 Jul 19.

Beyoglu Eye Training and Research Hospital, The University of Health Sciences, İstanbul, Turkey.

Macular telangiectasia type 2 (Mac Tel 2) is a bilateral disease of unknown cause with characteristic changes of the retinal vasculature. To the best of our knowledge, we could not find any reported cases of Mac Tel 2 with retinal arterial macroaneurysm (RAM). Our aim is to report a case of Mac Tel 2 with RAM. Read More

Am J Ophthalmol Case Rep 2018 Sep 21;11:98-100. Epub 2018 Jun 21.

L V Prasad Eye Institute, KAR Campus, Hyderabad, India.

Purpose: To describe a rare case of retinal racemose hemangioma (RRH) with retinal artery macroaneurysm (RAM) and its optical coherence tomography angiography (OCT-A) finding before and after treatment.

Observations: Congenital arteriovenous (AV) communications or RRH is a rare developmental anomaly associated with various ocular conditions. RRH alone is usually asymptomatic, and vision loss occurs when associated with other ocular complications like retinal vein occlusion, hemmorage, macular edema and macroaneurysm. Read More

Lasers Med Sci 2019 Feb 26;34(1):235-238. Epub 2018 May 26.

Beyoglu Eye Training and Research Hospital, The University of Health Sciences, İstanbul, Turkey.

Macular telangiectasia type 2 (Mac Tel 2) is a bilateral disease of unknown cause with characteristic changes of the retinal vasculature. To the best of our knowledge, we could not find any reported cases of Mac Tel 2 with retinal arterial macroaneurysm (RAM). Our aim is to report a case of Mac Tel 2 with RAM. Read More

Am J Ophthalmol Case Rep 2018 Jun 5;10:279-281. Epub 2018 Apr 5.

University of Michigan, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, United States.

Purpose: We present fundus and spectral domain optical coherence tomography findings of a patient with an arterial macroaneurysm of the optic disc.

Observations: An 87-year-old woman presented with blurry vision and was found to have a retinal arterial macroaneurysm on the optic disc. Spectral domain optical coherence tomography revealed abnormal saccular arterial dilatation on the disc with an elongation anteriorly and superficial prepapillary hemorrhages. Read More

Retin Cases Brief Rep 2018 Apr 24. Epub 2018 Apr 24.

Department of Ophthalmology, Intercity Hospital and University Paris Est, Créteil, France.

Purpose: To describe optical coherence tomography angiography (OCTA) findings in retinal arterial macroaneurysm (RAM) associated with macular edema and to correlate OCTA findings with conventional multimodal imaging.

Methods: The clinical course, conventional multimodal imaging findings including fundus color photography, spectral domain optical coherence tomography (Spectralis; Heidelberg Engineering, Heidelberg, Germany), fluorescein angiography (Heidelberg Engineering), and OCTA (Optovue, Inc, Freemont, CA) findings at baseline and during the follow-up of two eyes (two patients) with symptomatic RAM associated with macular edema were documented.

Results: Two eyes of 2 patients, both women, aged 82 and 46 years, which presented with progressive visual decline, were included. Read More

Case Rep Ophthalmol Med 2018 6;2018:5474903. Epub 2018 Mar 6.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

A case of retinal arterial macroaneurysm (RAM) is presented with multimodal imaging, including commercially available optical coherence tomography angiography (OCT-A). Following treatment with intravitreal bevacizumab, reduction of flow signal through the RAM is documented. OCT-A provides useful information for the diagnosis and management of at least some patients with RAM, without the need for traditional fluorescein angiography. Read More

Case Rep Ophthalmol 2018 Jan-Apr;9(1):113-119. Epub 2018 Feb 1.

Department of Ophthalmology, Mahoshi Hospital, Kobe, Japan.

Purpose: To report a case of macular hole (MH) secondary to a retinal arterial macroaneurysm (RAMA) which was successfully treated with an autologous transplantation of internal limiting membrane (ILM).

Case Report: An 87-year-old female presented with a sudden decrease in central vision in the right eye. A fundus examination revealed a RAMA in the superonasal macular region, a subretinal hemorrhage (SRH), involving the macula, and a sub-ILM hemorrhage. Read More

Ophthalmologe 2018 Dec;115(12):1059-1065

Augenklinik Tausendfensterhaus, Ruhrorter Str. 187, 47119, Duisburg-Ruhrort, Deutschland.

Acute premacular bleeding is often associated with vasoproliferative retinal changes, vascular anomalies or a Valsalva maneuver. The diagnosis is made during the funduscopic examination and can if necessary be confirmed with optical coherence tomography (OCT). This article presents a case example with a sub-inner limiting membrane (ILM)/sub-hyaloidal bleeding. Read More

Retina 2018 Mar 2. Epub 2018 Mar 2.

Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio.

Purpose: There is no established therapy for exudative-hemorrhagic complications in primary retinal arteriolar macroaneurysm (RAM).

Methods: Retrospective multicenter interventional study of anti-vascular endothelial growth factor in symptomatic RAMs. Central macular thickness in μm and best-corrected visual acuity in logMar were correlated with the RAM size and distance to the macula. Read More

Retina 2018 Feb 27. Epub 2018 Feb 27.

Machida Hospital, Kochi, Japan.

Semergen 2018 May - Jun;44(4):288-290. Epub 2018 Feb 13.

Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.

Arch Soc Esp Oftalmol 2018 Oct 15;93(10):e68. Epub 2018 Feb 15.

Servicio de Oftalmología, Hospital Universitario Fundación Alcorcón, Universidad Rey Juan Carlos, Alcorcón, Madrid, España.

Case Rep Ophthalmol 2017 Sep-Dec;8(3):503-509. Epub 2017 Oct 26.

University of Illinois College of Medicine, Peoria Campus, Peoria, Illinois, USA.

Objective: To report a case of recurrent vitreous hemorrhage from an optic nerve retinal arterial macroaneurysm (ONRAM) successfully treated with intraoperative endolaser.

Patient And Methods: A 92-year-old woman on oral aspirin and warfarin anticoagulation for atrial fibrillation developed three episodes of dense vitreous hemorrhage from an ONRAM. Due to failure of the vitreous hemorrhage to clear spontaneously, a total of three pars plana vitrectomy (PPV) procedures were performed along with a 1. Read More

Case Rep Ophthalmol Med 2017 4;2017:4630187. Epub 2017 Oct 4.

Sanliurfa Education and Research Hospital, Sanliurfa, Turkey.

A 55-year-old man presented with sudden deterioration of vision in the right eye. His visual acuity was reduced to hand motion because of a large multilevel premacular hemorrhage. Nd:YAG laser was performed to drain the entrapped hemorrhage under the internal limiting membrane (ILM) and posterior hyaloid face in the macula into the vitreous. Read More

Case Rep Ophthalmol 2017 May-Aug;8(2):390-395. Epub 2017 Jul 24.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.

Purpose: The aim of this report was to describe multimodal ocular imaging findings in a patient who presented with a ruptured retinal arterial macroaneurysm (RAM) associated with toxoplasmic Kyrieleis arteriolitis.

Methods: We report the case of a 64-year-old man with a history of systemic hypertension and dense amblyopia of the left eye who presented with decreased vision and new floaters in the left eye. Color fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, and indocyanine green angiography were used as diagnostic imaging tools. Read More

Asia Pac J Ophthalmol (Phila) 2017 Sep-Oct;6(5):444-449. Epub 2017 Aug 22.

Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

Purpose: To describe the efficacy of laser and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents for patients with symptomatic retinal arterial macroaneurysm (RAM).

Design: From 2009 to 2016, we collected patients with exudative or hemorrhagic RAM all treated by focal laser photocoagulation.

Methods: Nd:YAG laser was performed in patients with subinternal limiting membrane (sub-ILM) hemorrhage. Read More

Retin Cases Brief Rep 2017 Aug 9. Epub 2017 Aug 9.

*Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; †Vitreous Retina Macular Consultants of New York, New York, New York; ‡LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Institute, New York, New York; §Department of Ophthalmology, New York University School of Medicine, New York, New York; and ¶Division of Ophthalmology, Sao Paulo University Medical School, Sau Paulo, Brazil.

Purpose: Congenital retinal macrovessels are large aberrant retinal blood vessels that cross the horizontal raphe and can traverse the central macula. Using multimodal imaging and optical coherence tomography angiography, we describe 2 cases of congenital retinal macrovessel associated with macroaneurysms.

Methods: Two patients presented for evaluation and were found to have congenital retinal macrovessels associated with macroaneurysms. Read More

Case Rep Ophthalmol 2017 Jan-Apr;8(1):137-143. Epub 2017 Mar 7.

aAugenzentrum "Frohe Zukunft", Halle (Saale), Germany.

Introduction: Complex retinal arterial macroaneurysms (RAM) are often accompanied by hemorrhage and/or affect the macula. We evaluated the effect of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy using ranibizumab or aflibercept with or without laser photocoagulation in the treatment of macular edema due to RAM.

Methods: A case report of two patients with secondary macular edema caused by RAM is presented. Read More

Optom Vis Sci 2017 07;94(7):781-785

*MS, DNB †MBBS ‡MD Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India (all authors).

Purpose: Retinal arteriolar macroaneurysms are a common cause of vision loss in elderly patients with hypertension and cardiovascular disease. Their occurrence in the young, however, is not well known. The purpose of this article is to describe an unusual cause of retinal arteriolar macroaneurysm in a healthy young man. Read More

Retina 2018 Jan;38 Suppl 1:S114-S122

Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.

Purpose: To evaluate the clinical features of Type 1 idiopathic macular telangiectasia (IMT) followed up for 2 years.

Methods: Forty-nine patients with unilateral Type 1 IMT were examined. Thirty-one IMT eyes were treated with direct laser photocoagulation and/or intravitreal bevacizumab; the remaining 18 eyes, with good vision or slight macular edema, were untreated. Read More

Int J Ophthalmol 2017 18;10(3):491-493. Epub 2017 Mar 18.

Department of Ophthalmology, Faculty of Medicine, Ege University, Bornova 35040, İzmir, Turkey.

Clin Ophthalmol 2017 17;11:369-375. Epub 2017 Feb 17.

Department of Ophthalmology, Kobe City Medical Center General Hospital; Department of Ophthalmology, Institute of Biomedical Research and Innovation.

Purpose: Long-term outcomes of pars plana vitrectomy (PPV) for macular edema (ME) associated with branch retinal vein occlusion (BRVO) have been previously reported, but the studies did not report the number of additional treatments after surgery. During 5 years of follow-up, we therefore investigated the efficacy and safety of PPV for BRVO and evaluated the incidence of additional treatments.

Methods: We retrospectively reviewed the medical records of 25 eyes of 24 patients who underwent PPV for ME associated with BRVO and were followed up for at least 5 years. Read More

Int Ophthalmol 2019 Feb;39(2):273-274

ICARE Eye Hospital and Post Graduate Institute, Noida, UP, India.

Retin Cases Brief Rep 2019 Winter;13(1):10-14

Centre for Ophthalmology and Visual Science (incorporating Lions Eye Institute), The University of Western Australia, Perth, Western Australia, Australia.

Background/purpose: To report a case of a branch retinal vein occlusion secondary to a retinal arteriolar macroaneurysm (RAM).

Methods: Retrospective case report describing examination findings, treatment outcome and unique multimodal imaging features demonstrated on fluorescein angiography, optical coherence tomography, optical coherence tomography angiography and adaptive optics photography of the retinal vessels and RAM.

Results: A 61-year-old man presented with 20/200 vision in the right eye because of a branch retinal vein occlusion secondary to a RAM. Read More

Arch Soc Esp Oftalmol 2017 Mar 27;92(3):e17. Epub 2016 Dec 27.

Servicio de Oftalmología, Hospital Universitario Fundación Alcorcón, Madrid, España; Servicio de Oftalmología, Hospital General de Segovia, Segovia, España.

Saudi J Ophthalmol 2016 Oct-Dec;30(4):221-226. Epub 2016 Oct 13.

Aberdeen Royal Infirmary, Aberdeen, UK; Royal Hallamshire Hospital Sheffield, UK.

Purpose: To evaluate the outcomes of pneumatic displacement of submacular hemorrhage secondary to choroidal neovascular membrane (CNV) ( = 9) and retinal arterial macroaneurysm (RAM) ( = 3).

Methods: This is a retrospective case series study of 12 eyes from 12 patients in Aberdeen Royal Infirmary, Aberdeen, UK. The mean duration of visual loss was 10. Read More

Clin Exp Ophthalmol 2017 Jan 21;45(1):45-53. Epub 2017 Jan 21.

Save Sight Institute, Sydney University, Sydney, New South Wales, Australia.

Hypertension is a risk factor for a number of vision-threatening eye conditions including retinal vascular occlusion, retinal macroaneurysm and non arteritic anterior ischaemic optic neuropathy. In addition, hypertension may exacerbate the vision-threatening effects of diabetic retinopathy and has been implicated in the pathogenesis of age-related macular degeneration. The effects of sustained hypertension are directly visible in the eye as hypertensive retinopathy and choroidopathy, reflecting a pathological process occurring throughout the body. Read More

J Fr Ophtalmol 2017 Jan 14;40(1):e11-e13. Epub 2016 Nov 14.

Department of ophtalmology, Habib Bourguiba University Hospital, Faculty of Medecine, University of Sfax, Sfax, Tunisia.

Eur J Ophthalmol 2017 Mar 7;27(2):215-219. Epub 2016 Sep 7.

2 Department of Ophthalmology, Ophthalmiatrion Athinon, Athens - Greece.

Purpose: To evaluate the potential efficacy and safety of primary intravitreal ranibizumab in patients with symptomatic retinal arterial macroaneurysm (RAM).

Methods: This prospective study comprised 5 eyes with RAM treated with intravitreal ranibizumab. At baseline, all patients underwent best-corrected visual acuity (BCVA) measurement, ophthalmic examination including slit-lamp biomicroscopy, and central foveal thickness (CFT) measurement using optical coherence tomography. Read More

Graefes Arch Clin Exp Ophthalmol 2016 Nov 25;254(11):2203-2207. Epub 2016 May 25.

Department of Ophthalmology, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland.

Purpose: Symptomatic retinal arterial macroaneurysms (RAM) are primarily investigated by fundus fluorescein angiography after presenting with visual disturbance. The natural history includes spontaneous regression and occasionally occlusion of the arteriole distal to the aneurysm. RAM may be managed conservatively. Read More

Ophthalmology 2016 11;123(11):2327

Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.

Case Rep Ophthalmol Med 2016 25;2016:9858291. Epub 2016 Sep 25.

Cincinnati Eye Institute, Cincinnati, OH, USA; Department of Ophthalmology, Bahcesehir University Faculty of Medicine, Istanbul, Turkey.

. To introduce a clinical sign on spectral domain optical coherence tomography (SDOCT), which may indicate high risk for full-thickness macular hole formation after internal limiting membrane (ILM) peeling. . Read More

Case Rep Ophthalmol 2016 Jan-Apr;7(1):243-8. Epub 2016 May 19.

Department of Ophthalmology, Osaka Medical College, Takatsuki, Japan.

Purpose: Retinal arterial macroaneurysm (RAM) has been reported in association with branch retinal vein occlusion (BRVO), and usually BRVO precedes RAM. We present a long-term follow-up case report of unilateral multiple RAMs that developed BRVO following ruptured RAM in the same retinal quadrant.

Case Presentation: An 80-year-old woman presented with floaters in her right eye in June 2012. Read More

Retin Cases Brief Rep 2017 Summer;11(3):211-216

Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel.

Purpose: To describe the advantages of en face view with swept-source optical coherence tomography in assessing the morphologic features of retinal arterial macroaneurysms, their consequences on adjacent retina, planning laser treatment, and evaluating its effects.

Methods: Three eyes were treated for retinal arterial macroaneurysms and followed by swept-source optical coherence tomography in 2014-2015. En face images of the retina and choroid were obtained by EnView, a swept-source optical coherence tomography program. Read More

Retin Cases Brief Rep 2017 Winter;11(1):12-14

Wills Eye Hospital Retina Service, Philadelphia, Pennsylvania.

Purpose: To describe multimodal imaging findings in a patient presenting with an occult optic disk macroaneurysm.

Methods: A 54-year-old woman presented with decreased vision in the right eye secondary to preretinal, intraretinal, and optic disk hemorrhage.

Results: Ancillary fluorescein angiography revealed evidence of an occult optic disk macroaneurysm that was not realized on fundoscopic examination. Read More

Acta Ophthalmol 2016 Sep 27;94(6):e517-9. Epub 2015 Nov 27.

Laboratory of Retinal Cell Biology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

Saudi J Ophthalmol 2015 Oct-Dec;29(4):292-4. Epub 2015 Mar 18.

Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.

Congenital retinal macrovessel (CRM) refers to an aberrant vessel, usually a vein, which traverses the macula and supplies both sides of the horizontal raphe. It is a rare condition, mostly asymptomatic and discovered on routine examination. We describe a case of both arterial and venous CRM with a macroaneurysm along the arterial CRM that presented with decreased vision due to prominent lipid exudation at the macula. Read More

Int J Clin Exp Med 2015 15;8(7):11572-8. Epub 2015 Jul 15.

Department of Biostatistics and Medical Informatics of Akdeniz University Medical Faculty Antalya, Turkey.

Aim: To evaluate the anatomic and functional results of intravitreal ranibizumab injection for treatment of symptomatic retinal arterial macroaneurysm (RAM).

Materials And Methods: A series of seven patients (seven eyes) who had been diagnosed with symptomatic RAM were assessed by comprehensive ophthalmologic examination, fluorescein angiography (FA), optical coherence tomography (OCT), and indocyanine green angiography (ICGA). All patients were treated by intravitreal ranibizumab injection within one week of diagnosis and retreated upon evidence of persistent serous detachment or hemorrhage involving the macula on OCT. Read More

Middle East Afr J Ophthalmol 2015 Jul-Sep;22(3):396-8

Department of Vitreo-Retina, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Thavalakuppam, Puducherry, India.

A 50-year-old Indian male presented with defective vision in the right eye for 6 months. He was diagnosed to have idiopathic macular telangiectasia (IMT) type 1 associated with diffuse macular edema and multiple retinal arterial macroaneurysms (RAM). Intravitreal bevacizumab was administered for the treatment of macular edema, following which there was a rupture of a preexisting RAM with multilevel retinal hemorrhages. Read More

Eur J Ophthalmol 2016 Jan-Feb;26(1):36-43. Epub 2015 Jul 2.

From Fondation Ophtalmologique Adolphe de Rothschild, Paris - France.

Purpose: To describe clinical, angiographic, and tomographic features and the therapeutic management of patients with retinal arterial macroaneurysm (RAM).

Methods: Retrospective analysis of patients diagnosed with RAM between January 2011 and September 2014 in Professor Sahel's Department of Ophthalmology, Rothschild Foundation. Retinal arterial macroaneurysms were classified as hemorrhagic, exudative, or quiescent. Read More

Case Rep Ophthalmol 2015 May-Aug;6(2):170-5. Epub 2015 Jun 2.

Department of Ophthalmology, Pedro Hispano Hospital, Matosinhos, Portugal.

Purpose: We report a case of a foveal macroaneurysm with long-standing macular edema in a rare location, successfully treated with intravitreal ranibizumab.

Methods: We report the case of a 52-year-old man with left eye long-term visual loss due to macular edema caused by a retinal macroaneurysm, localized about 400 μm from the center of the fovea, and its response to 6 monthly ranibizumab intravitreal injections. His best-corrected visual acuity and morphological data evaluated by optical coherence tomography and fluorescein angiography are presented. Read More

Retina 2015 Dec;35(12):2537-42

*Ophthalmic Imaging Center, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio; and †Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.

Purpose: To evaluate the feasibility and utility of intraoperative optical coherence tomography (OCT) during pars plana vitrectomy surgery for dense vitreous hemorrhage.

Methods: The Prospective Assessment of Intraoperative and Perioperative OCT for Ophthalmic Surgery study examined the utility of intraoperative OCT in ophthalmic surgery. Intraoperative scanning was performed with a microscope-mounted spectral domain OCT system. Read More

Klin Monbl Augenheilkd 2015 Apr 22;232(4):566-7. Epub 2015 Apr 22.

Augenklinik der Universitätsmedizin, Johannes Gutenberg-Universität, Mainz (Direktor: Univ.-Prof. Dr. med. N. Pfeiffer).