8,325 results match your criteria MCN - The American Journal of Maternal/Child Nursing [Journal]


An osteoclast-like giant cell tumor embedded in the mural nodule of a pancreatic mucinous cystic neoplasm: A case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15246

Peking University China-Japan Friendship School of Clinical Medicine.

Rationale: Mucinous cystic neoplasms (MCNs) are relatively rare lesions, accounting for 2%-5% of all exocrine pancreatic neoplasms. MCNs mainly occur in women (female:male ratio = 20:1), with a peak incidence in the 5th decade of life. Osteoclast-like giant cell tumors (OGCTs) are rare and relatively aggressive neoplasms, comprising <1% of all pancreatic carcinomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000015246DOI Listing

Fathering on Tenuous Ground: A Qualitative Meta-Synthesis on Teen Fathering.

MCN Am J Matern Child Nurs 2019 Apr 17. Epub 2019 Apr 17.

Lee SmithBattle is a Professor of Nursing, School of Nursing, Saint Louis University, Saint Louis, MO. The author can be reached via e-mail at Wisitsri Phengnum is a Doctoral Student, School of Nursing, Saint Louis University, Saint Louis, MO. Anne Winnie Shagavah is a Doctoral Candidate, School of Nursing, Saint Louis University, Saint Louis, MO. Satoko Okawa is an Associate Professor of Nursing, School of Nursing, Osaka Prefecture University, Osaka, Japan.

Background: Although teen fathers are a vulnerable group of parents, they have received far less attention than teen mothers.

Purpose: We conducted a systematic search of qualitative studies that examined their prenatal and postpartum experience to better understand teen fathers' concerns, strengths, and vulnerabilities.

Methods: We searched nine electronic databases through September 2017; 29 studies represented in 30 articles met study criteria. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000536DOI Listing

Isolation, Identification, and Quantification of Tyrosinase and α-Glucosidase Inhibitors from UVC-Irradiated Mulberry ( L.) Leaves.

Prev Nutr Food Sci 2019 Mar 15;24(1):84-94. Epub 2018 Nov 15.

Department of Food Science and Nutrition, Daegu Catholic University, Gyeongbuk 61848, Korea.

Methanol extracts from ultraviolet (UV) C-irradiated mulberry leaves (UVC-IML) exhibit stronger tyrosinase and α-glucosidase inhibitory activities than those from unirradiated mulberry leaves. Through a bioassay-guided fractionation and purification process, two oxyresveratrol derivatives, oxyresveratrol (ORT) and 4'-prenyloxyresveratrol (PORT), and six 2-arylbenzofuran derivatives [moracin B (MCB), moracin C (MCC), moracin M (MCM), moracin N (MCN), 6,5'-dimethoxymoracin M (DMMCM), and chalcomoracin (CMC)] were isolated from the methanol extract from UVC-IML. Their chemical structures were determined by UV, mass, and nuclear magnetic resonance spectrometry. Read More

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http://dx.doi.org/10.3746/pnf.2019.24.1.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456241PMC

Work-up for Fever During Neutropenia for Both the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient.

Infect Dis Clin North Am 2019 Jun;33(2):381-397

Division of Infectious Diseases, Vanderbilt University Medical Center, A2200 MCN, 1161 21st Avenue South, Nashville, TN 37232-2605, USA. Electronic address:

Fever is a common complication in patients with underlying neutropenia and is associated with significant mortality in neutropenic patients with acute myelogenous leukemia or hematopoietic cell transplant. Fever may be the only sign of infection and requires further clinical assessment, including a history, a physical examination, and additional laboratory and radiographic testing. National and international guidelines recommend initiation of empiric antimicrobial therapy in patients with fever during neutropenia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08915520193000
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http://dx.doi.org/10.1016/j.idc.2019.02.003DOI Listing
June 2019
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Acute and subsequent continuation electroconvulsive therapy elevates serum BDNF levels in patients with major depression.

Brain Stimul 2019 Feb 26. Epub 2019 Feb 26.

Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090, Vienna, Waehringerstr 18-20, Austria. Electronic address:

Introduction: The induction of brain-derived neurotrophic factor (BDNF) release and subsequent restoration of neuroplastic homeostasis may underlie the effects of electroconvulsive therapy (ECT).

Objectives: We aimed to assess serum and plasma BDNF levels during the course of acute ECT, as well as before and after subsequent continuation ECT, in patients with depression.

Methods: We included 24 patients with major depressive disorder (mean age ± SD: 54. Read More

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http://dx.doi.org/10.1016/j.brs.2019.02.015DOI Listing
February 2019
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Evaluation of the genotoxicity of neurotoxic insecticides using the micronucleus test in Tradescantia pallida.

Chemosphere 2019 Apr 12;227:371-380. Epub 2019 Apr 12.

Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, 38900-402, Uberlândia, Minas Gerais, Brazil.

Neonicotinoids and phenylpyrazoles are classes of neurotoxic insecticides which are able to bind at different ligand sites of neural receptors, leading to the deregulation of insect neural activity and hence resulting in death. The misuse or indiscriminate use of these chemicals is directly associated with several toxicological effects in biota and at different trophic levels. Based on this premise, the aim of the present study was to evaluate and compare the genotoxic capacity of different concentrations of thiamethoxam (TMX), acetamiprid (ACP), imidacloprid (IMI) and fipronil (FP) through the Micronucleus Test in Tradescantia pallida (Trad-MCN). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00456535193072
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http://dx.doi.org/10.1016/j.chemosphere.2019.04.073DOI Listing
April 2019
1 Read

The March for Moms.

Authors:
Ginger Breedlove

MCN Am J Matern Child Nurs 2019 Apr 16. Epub 2019 Apr 16.

Ginger Breedlove, PhD, CNM, FACNM, FAAN President and Co-founder, March for Moms.

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http://dx.doi.org/10.1097/NMC.0000000000000544DOI Listing

Klotho deficiency affects the spine morphology and network synchronization of neurons.

Mol Cell Neurosci 2019 Apr 13;98:1-11. Epub 2019 Apr 13.

Department of Neurobiology, University of Alabama at Birmingham, 1825 University Blvd. Shelby 913, Birmingham 35294, AL, USA. Electronic address:

Klotho-deficient mice rapidly develop cognitive impairment and show some evidence of the onset of neurodegeneration. However, it is impossible to investigate the long-term consequences on the brain because of the dramatic shortening of lifespan caused by systemic klotho deficiency. As klotho expression is downregulated with advancing organismal age, understanding the mechanisms of klotho action is important for developing novel strategies to support healthy brain aging. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10447431183038
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http://dx.doi.org/10.1016/j.mcn.2019.04.002DOI Listing
April 2019
5 Reads

Mesoporous graphitic carbon nitride as an efficient sorbent for extraction of sulfonamides prior to HPLC analysis.

Mikrochim Acta 2019 Apr 11;186(5):279. Epub 2019 Apr 11.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, 999077, China.

Mesoporous graphitic carbon nitride (MCN) is shown to be a viable sorbent for the enrichment of sulfonamides (SAs). To overcome the difficulty of separating the sorbent from the matrix, a novel type kind of column-assisted dispersive solid-phase extraction (CA-dSPE) method was designed. The MCN was characterized by scanning electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, fourier transform infrared spectroscopy and nitrogen adsorption-desorption measurements. Read More

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http://link.springer.com/10.1007/s00604-019-3394-9
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http://dx.doi.org/10.1007/s00604-019-3394-9DOI Listing
April 2019
2 Reads

Delivery type, opioid prescribing, and the risk of persistent opioid use after delivery.

Am J Obstet Gynecol 2019 Apr 25;220(4):405-407. Epub 2018 Oct 25.

Department of Health Policy, Department of Medicine, Geriatric Research Education and Clinical Center, Nashville, TN 37232.

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https://linkinghub.elsevier.com/retrieve/pii/S00029378183091
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http://dx.doi.org/10.1016/j.ajog.2018.10.026DOI Listing
April 2019
1 Read

An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62.

Mol Cell Neurosci 2019 Apr 4. Epub 2019 Apr 4.

Harry Perkins Institute of Medical Research, University of Western Australia, Nedlands, Western Australia, Australia; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Electronic address:

Elevated oxidative stress has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). In response to oxidative stress, the Nrf2 transcription factor activates protective antioxidant genes. A critical regulator of Nrf2 is the inhibitory protein Keap1, which mediates Nrf2 degradation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10447431183036
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http://dx.doi.org/10.1016/j.mcn.2019.04.001DOI Listing
April 2019
5 Reads

Symmetry-Breaking Synthesis of Multicomponent Nanoparticles.

Acc Chem Res 2019 Apr 3;52(4):1125-1133. Epub 2019 Apr 3.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science , Fudan University , Shanghai 200438 , P.R. China.

Multicomponent nanoparticles (MCNs) composed of disparate inorganic colloidal components have attracted great attention from researchers in both the academic and industrial community, because of their unique properties and diverse applications in energy conversion and storage; heterogeneous catalysis; optics and electronics; and biomedical imaging, diagnosis, and therapy. Compared with single-component nanoparticles (NPs), new or advanced properties of MCNs arise from the synergistic effect between their constituent components and the presence of nanoscale interfaces between distinct materials within the particles. Consequently, the spatial arrangement of nanoscale domains of MCNs becomes equally important in property or function control of MCNs as their size, shape, and composition, if not more. Read More

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http://dx.doi.org/10.1021/acs.accounts.9b00038DOI Listing

Mucinous cystic neoplasm of the pancreas assessed with a real-time three-dimensional imaging using a transesophageal echocardiography probe.

Clin J Gastroenterol 2019 Apr 2. Epub 2019 Apr 2.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

Ultrasonographic imaging techniques have been rapidly developing. The new transesophageal echocardiography (TEE) system made it possible to obtain the real-time three-dimensional (3D) image of the cardiac system through the esophagus, that can be applied to the field of gastroenterology. We herein present a case of 72-year-old woman who was referred for evaluation of an incidentally found cystic lesion in the tail of the pancreas. Read More

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http://dx.doi.org/10.1007/s12328-019-00975-xDOI Listing
April 2019
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Pimavanserin for Psychosis in Parkinson's Disease-Related Disorders: A Retrospective Chart Review.

Drugs Aging 2019 Mar 29. Epub 2019 Mar 29.

Department of Neurology, Division Behavioral and Cognitive Neurology, Vanderbilt University Medical Center, 1161 21st Avenue, A-0118 MCN, Nashville, TN, 37232, USA.

Background: Psychosis is common in Parkinson's disease-related disorders and is associated with significant morbidity. Pimavanserin is a newly approved treatment for Parkinson's disease psychosis, but real-world experience with pimavanserin has been limited by small sample sizes and limited assessment of longitudinal outcomes.

Objective: The aim was to summarize the clinical experience with pimavanserin in a large cohort of patients with Parkinson's disease-related psychosis. Read More

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http://dx.doi.org/10.1007/s40266-019-00655-yDOI Listing

Has the Scottish Managed Clinical Network for Sarcoma influenced the survival outcomes for primary malignant bone tumours?

Authors:
F MacDonald S Gupta

J Orthop 2019 May-Jun;16(3):254-259. Epub 2019 Mar 7.

NHS Greater Glasgow and Clyde, UK.

Primary malignant bone tumours (PMBT) are rare. We have reviewed patient outcomes in Scotland over a 20 year period and provided an update on the principles of current management strategies for the non-specialist practitioner. The Scottish Managed Clinical Network for Sarcoma (MCN) connects the three main management centres for sarcoma in Scotland: Glasgow, Aberdeen and Edinburgh. Read More

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http://dx.doi.org/10.1016/j.jor.2019.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423303PMC

Factors Associated With Nonadherence to Pelvic Floor Physical Therapy Referral for the Treatment of Female Pelvic Pain.

Phys Ther 2019 Mar 27. Epub 2019 Mar 27.

Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, 1161 21st Ave, MCN B-1100, Nashville, TN 37232 (USA).

Background: Patients with pelvic pain due to pelvic floor myofascial pain syndrome are often referred for pelvic floor physical therapy, the primary treatment option. However, many patients do not adhere to the treatment.

Objective: The purpose of this study was to examine the adherence rate and outcomes of patients referred for physical therapy for pelvic floor myofascial pain syndrome, and identify risk factors associated with nonadherence. Read More

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http://dx.doi.org/10.1093/ptj/pzz050DOI Listing
March 2019
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Home-Time Is a Feasible and Valid Stroke Outcome Measure in National Datasets.

Stroke 2019 May;50(5):1282-1285

Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (P.L., T.J.Q.).

Background and Purpose- Home-time (HT) is a stroke outcome measure based on time spent at home after stroke. We hypothesized that HT assessment would be feasible and valid using national data. Methods- We linked the Scottish Stroke Care Audit to routine healthcare data and calculated 90-day HT for all strokes, 2005 to 2017. Read More

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http://dx.doi.org/10.1161/STROKEAHA.118.023916DOI Listing

Women's Experiences with Tandem Breastfeeding.

MCN Am J Matern Child Nurs 2019 Mar 18. Epub 2019 Mar 18.

Molly Patricia O'Rourke is a graduate of the second-degree accelerated BSN program at University of Pennsylvania School of Nursing, Philadelphia, PA. She will enter University of Pennsylvania MSN program in Midwifery in May 2019 and has a special interest in perinatal mood disorders. Diane Lynn Spatz is a Professor of Perinatal Nursing and the Helen M. Shearer Professor of Nutrition School of Nursing, University of Pennsylvania, Philadelphia, PA; and Nurse Researcher and Director of the Lactation Program at the Children's Hospital of Philadelphia (CHOP) and Director of CHOP's Mothers' Milk Bank. Dr. Spatz can be reached at

Background: Choosing to breastfeed is a decision with far-reaching benefits; strengthened immune systems, all-encompassing nutrition, and fostering healthy attachment. For these and other reasons, some mothers are reluctant to wean their child due to a subsequent pregnancy. Mothers may breastfeed throughout their second pregnancy, give birth to their second child, and simultaneously breastfeed two children. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000534DOI Listing

Oxytocin Guidelines Associated with Compliance to National Standards.

MCN Am J Matern Child Nurs 2019 Apr 2. Epub 2019 Apr 2.

Jodi K. Jackson is a Neonatologist, Children's Mercy-Kansas City, University of Missouri-Kansas City School of Medicine, Department of Pediatrics, Kansas City, MO. The author can be reached via e-mail at Elizabeth Wickstrom is a Maternal-Fetal Medicine Specialist, Obstetrix Medical Group of Kansas and Missouri, Shawnee Mission Medical Center, Merriam, KS. Betsi Anderson is an Administrative Director, Children's Mercy-Kansas City, Kansas City, MO.

Objective: Develop a program that built a multidisciplinary, consensus-driven, evidence-based approach to oxytocin use, while adhering to national guidelines.

Design: This was a quality improvement project that used the Plan Do Study Act method to create cycles of change over several years. To initiate discussion, a survey was administered at a social event for providers from divergent community practices that addressed the controversial aspects of oxytocin use. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000520DOI Listing
April 2019
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Nurses' Views on Using Pasteurized Donor Human Milk for Hypoglycemic Term Infants.

MCN Am J Matern Child Nurs 2019 Mar 14. Epub 2019 Mar 14.

Debi Ferrarello is Director of Program Development, Women's Health Service Line, Director of Parent Education and Lactation, Penn Medicine's Pennsylvania Hospital, Philadelphia, PA. The author can be reached via e-mail at Elizabeth B. Froh is Nurse Scientist for Pediatric Nursing Research and Evidence-Based Practice, Children's Hospital of Philadelphia, Philadelphia, PA. Tyonne D. Hinson is Director, Nursing Diversity Initiatives, Boston Children's Hospital, Boston, MA. Diane L. Spatz is Professor of Perinatal Nursing & Helen M. Shearer Professor of Nutrition, University of Pennsylvania School of Nursing, Nurse Researcher & Manager of Lactation Program, The Children's Hospital of Philadelphia (CHOP), Clinical Coordinator of the CHOP's Mothers' Milk Bank, Philadelphia, PA.

Purpose: The purpose of this study was to explore maternal child nurses' knowledge and beliefs about using pasteurized donor human milk (PDHM) to treat newborns with hypoglycemia. Pasteurized donor human milk has been used for decades in neonatal intensive care units, but its use is relatively new in the well-baby population.

Study Design And Methods: Focus groups of maternal child nurses were conducted to explore this topic. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000525DOI Listing
March 2019
1 Read

Small molecules as therapeutic drugs for Alzheimer's disease.

Mol Cell Neurosci 2019 Apr 12;96:47-62. Epub 2019 Mar 12.

Internal Medicine Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, United State; Garrison Institute on Aging, South West Campus, Texas Tech University Health Sciences Center, 6630 S. Quaker Suite E, Lubbock, TX 79413, United States; Cell Biology & Biochemistry Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, United States; Pharmacology & Neuroscience Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, United States; Neurology Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, United States; Speech, Language and Hearing Sciences Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, United States; Department of Public Health, Graduate School of Biomedical Sciences, 3601 4th Street, Lubbock, TX 79430, United States. Electronic address:

Mitochondrial dysfunction is a central protagonist of Alzheimer's disease (AD) pathogenesis. Mitochondrial dysfunction stems from various factors including mitochondrial DNA damage and oxidative stress from reactive oxygen species, membrane and ionic gradient destabilization, and interaction with toxic proteins such as amyloid beta (Aβ). Therapeutic drugs such as cholinesterase and glutamate inhibitors have proven to improve synaptic neurotransmitters, but do not address mitochondrial dysfunction. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.03.001DOI Listing
April 2019
2 Reads

Modulation of Ca2.3 channels by unconjugated bilirubin (UCB) - Candidate mechanism for UCB-induced neuromodulation and neurotoxicity.

Mol Cell Neurosci 2019 Apr 12;96:35-46. Epub 2019 Mar 12.

Institute for Neurophysiology, University of Cologne, Germany. Electronic address:

Elevated levels of unbound unconjugated bilirubin (UCB) can lead to bilirubin encephalopathy and kernicterus. In spite of a large number of studies demonstrating UCB-induced changes in central neurotransmission, it is still unclear whether these effects involve alterations in the function of specific ion channels. To assess how different UCB concentrations and UCB:albumin (U/A) molar ratios affect neuronal R-type voltage-gated Ca channels, we evaluated their effects on whole-cell currents through recombinant Ca2. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.03.003DOI Listing
April 2019
1 Read
3.840 Impact Factor

Recurrent palaeo-wildfires in a Cisuralian coal seam: A palaeobotanical view on high-inertinite coals from the Lower Permian of the Paraná Basin, Brazil.

PLoS One 2019 14;14(3):e0213854. Epub 2019 Mar 14.

Programa de Pós-Graduação em Ambiente e Desenvolvimento (PPGAD), Universidade do Vale do Taquari-Univates, Lajeado, Rio Grande do Sul, Brazil.

Distribution and abundance of charcoal in coal seams (in form of pyrogenic macerals of the inertinites group) have been considered as a reliable tool to interpret the local and regional palaeo-wildfire regimes in peat-forming depositional environments. Although the occurrence of inertinites is globally well documented for the Late Palaeozoic, the description of palaeobotanical evidence concerning the source plants of such charcoal is so far largely missing. In the present study, we provide the first detailed analysis of macro-charcoal preserved in the Barro Branco coal seam, Rio Bonito Formation, Cisuralian of the Paraná Basin, Santa Catarina State, Brazil. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213854PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417680PMC
March 2019
2 Reads

The Power of Design Thinking in Medical Education.

Acad Radiol 2019 Mar 11. Epub 2019 Mar 11.

Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, 1161 21st Ave. S, CCC-1118 MCN, Nashville, TN 37232.

A goal of medical education should be to optimize educational experiences of our learners. How can we better understand their experiences and design educational activities that inspire them to learn? Design Thinking is a powerful process that consists of five iterative phases: empathize, define, ideate, prototype, and test. Empathy with the user experience is at the core of Design Thinking. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10766332193007
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http://dx.doi.org/10.1016/j.acra.2019.02.012DOI Listing
March 2019
7 Reads

Growth and excitability at synapsin II deficient hippocampal neurons.

Mol Cell Neurosci 2019 Apr 9;96:25-34. Epub 2019 Mar 9.

Department of Neurology, Wayne State University School of Medicine, Detroit, MI, United States of America. Electronic address:

Synapsins are neuronal phosphoproteins that fine-tune synaptic transmission and suppress seizure activity. Synapsin II (SynII) deletion produces epileptic seizures and overexcitability in neuronal networks. Early studies in primary neuronal cultures have shown that SynII deletion results in a delay in synapse formation. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.03.002DOI Listing

Same-Sex Mothers and Lactation.

MCN Am J Matern Child Nurs 2019 Mar 7. Epub 2019 Mar 7.

Nina A. Juntereal is a Nursing Student, University of Pennsylvania School of Nursing, Philadelphia, PA. Diane L. Spatz is a Professor of Perinatal Nursing & Helen M. Shearer Professor of Nutrition, University of Pennsylvania School of Nursing, Nurse Researcher & Manager of Lactation Program, The Children's Hospital of Philadelphia (CHOP), Clinical Coordinator of the CHOP's Mothers' Milk Bank, Philadelphia, PA. Dr. Spatz can be reached at

Investigation of the needs of same-sex mothers practicing lactation is limited in the nursing literature. The heteronormative structure of the healthcare system has stigmatized these postpartum women and minimized the level of nursing care provided. Case reports demonstrate that same-sex mothers value inclusivity and understanding of their healthcare needs that is missing in healthcare settings. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000519DOI Listing
March 2019
1 Read

Minimally Invasive Approaches to Pancreatic Cancer.

Surg Oncol Clin N Am 2019 04 10;28(2):255-272. Epub 2019 Feb 10.

Department of General Surgery, Mayo Clinic, Davis 3N, 4500 San Pablo Road, Jacksonville, FL 32224, USA; Miami Cancer Institute, 8900 North Kendall Drive, Miami, FL 33176, USA; Mayo Clinic College of Medicine and Sciences, 200 First Street South West, Rochester, MN 55905, USA.

In pancreatic cancer, resection combined with neoadjuvant and/or adjuvant therapy remains the only chance for cure and/or prolonged survival. A minimally invasive approach to pancreatic cancer has gained increased acceptance and popularity. The aim of minimally invasive surgery of the pancreas includes limiting trauma, decreasing length of hospitalization, lessening cost, decreasing blood loss, and allowing for a more meticulous oncologic dissection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10553207183070
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http://dx.doi.org/10.1016/j.soc.2018.11.006DOI Listing
April 2019
7 Reads

Middle cluneal nerve entrapment mimics sacroiliac joint pain.

Acta Neurochir (Wien) 2019 Apr 4;161(4):657-661. Epub 2019 Mar 4.

Department of Neurosurgery, Kushiro Rosai Hospital, 13-23, Nakazono-cho, Kushiro, Hokkaido, Japan.

Background: Sacroiliac joint (SIJ)-related pain is associated with low back- and buttock pain and the SIJ score is diagnostically useful because it helps to differentiate between SIJ-related pain and pain due to other factors such as lumbar disc herniation and lumbar spinal canal stenosis. Middle cluneal nerve (MCN) entrapment (MCN-E) can produce pain involving the lower back and buttocks. Therefore, the origin of the pain must be identified. Read More

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http://link.springer.com/10.1007/s00701-019-03861-0
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http://dx.doi.org/10.1007/s00701-019-03861-0DOI Listing
April 2019
4 Reads

Re-visiting the brachialis muscle: morphology, morphometry, gender diversity, and innervation.

Surg Radiol Anat 2019 Apr 28;41(4):393-400. Epub 2019 Feb 28.

Department of Anatomy, Faculty of Medicine, University of Ruhuna, P.O. Box 70, Galle, Sri Lanka.

Purpose: The brachialis (BM) is a complex muscle with a long-running controversy regarding its morphology and innervation. The primary objective of this study was to elucidate the detailed gross morphology of BM in an adult Sri Lankan population.

Method: Cadaveric upper limbs (n = 240) were examined for the proximal and distal attachments, length, width, thickness of BM, and innervations by the musculocutaneous (MCN) and radial nerve (RN). Read More

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http://dx.doi.org/10.1007/s00276-019-02182-2DOI Listing

Missed Monoclonal Disease Manifesting in Early Post-renal Transplant Period.

Indian J Nephrol 2019 Jan-Feb;29(1):65-69

Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A 63-year-old diabetic gentleman with microvascular complications presented with advanced azotemia and anemia. He was stabilized with blood transfusion and hemodialysis. With the probable diagnosis of diabetic nephropathy-related end-stage renal disease, he underwent kidney transplantation. Read More

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http://dx.doi.org/10.4103/ijn.IJN_384_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375021PMC

Characteristics and long-term survival of resected pancreatic cystic neoplasms in Finland. The first nationwide retrospective cohort analysis.

Pancreatology 2019 Apr 14;19(3):456-461. Epub 2019 Feb 14.

Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; Faculty of Medicine and Life Sciences, University of Tampere, Finland. Electronic address:

Background: Pancreatic cystic neoplasms (PCN) are being found increasingly in imaging studies. Even though the characteristics of PCN lesions have been studied extensively in single and multicentre settings, nationwide data is lacking. The aim of this study was to determine the nationwide epidemiologic characteristics and long-term survival of all resected PCNs. Read More

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http://dx.doi.org/10.1016/j.pan.2019.02.007DOI Listing

Fluid and imaging biomarkers for Huntington's disease.

Mol Cell Neurosci 2019 Feb 23. Epub 2019 Feb 23.

Huntington's Disease Centre, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom. Electronic address:

Huntington's disease is a chronic progressive neurodegenerative condition for which there is no disease-modifying treatment. The known genetic cause of Huntington's disease makes it possible to identify individuals destined to develop the disease and instigate treatments before the onset of symptoms. Multiple trials are already underway that target the cause of HD, yet clinical measures are often insensitive to change over typical clinical trial duration. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.02.004DOI Listing
February 2019

A System-Wide Approach to Prevention of In-Hospital Newborn Falls.

Authors:

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):E7-E8

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http://dx.doi.org/10.1097/NMC.0000000000000531DOI Listing
February 2019

Women's Experiences of Breastfeeding-Related Pain.

Authors:

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):E5-E6

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http://dx.doi.org/10.1097/NMC.0000000000000530DOI Listing
February 2019

Overcoming Illiteracy in Women and Girls.

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):118

Lynn Clark Callister is a Professor Emerita, College of Nursing, Brigham Young University, Provo, UT, and an Editorial Board Member of MCN. Dr. Callister can be reached via e-mail at

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http://dx.doi.org/10.1097/NMC.0000000000000504DOI Listing
February 2019

A Call to Action: The Needs of Breastfeeding Mothers on College and University Campuses.

Authors:
Diane L Spatz

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):117

Dr. Spatz is a Professor of Perinatal Nursing & the Helen M. Shearer Professor of Nutrition at the University of Pennsylvania. She holds a joint appointment with the Children's Hospital of Philadelphia (CHOP) where she is a nurse researcher, director of the lactation program, and clinical coordinator of CHOP's Mothers' Milk Bank. Dr. Spatz can be reached via e-mail at

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http://dx.doi.org/10.1097/NMC.0000000000000514DOI Listing
February 2019

Twins: The Importance of Chorionicity in Planning Care and Timing of Birth.

Authors:
Molly M Killion

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):115

Molly Killion is the High-Risk Obstetric Program Nurse Coordinator at University of California San Francisco Medical Center in San Francisco, CA. Dr. Killion can be reached via e-mail at

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http://dx.doi.org/10.1097/NMC.0000000000000507DOI Listing
February 2019

Oral Sucrose Versus Breastfeeding in Managing Infants' Immunization-Related Pain: A Randomized Controlled Trial.

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):108-114

Rasha F. Gad is an Assistant Lecturer of Pediatric Nursing, School of Nursing, Mansoura University, Mansoura, Egypt. The author can be reached via email at Donna A. Dowling is a Professor, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH. Fawzia E. Abusaad is an Assistant Professor of Pediatric Nursing, Mansoura University, Mansoura, Egypt. Mohamed R. Bassiouny is a Professor of Pediatrics/Neonatology, Mansoura University, Mansoura, Egypt. Magda A. Abd Elaziz is a Lecturer of Pediatric Nursing, Mansoura University, Mansoura, Egypt.

Background: Treating pain during immunization should be a part of pediatric primary healthcare around the world, as untreated pain in children has short- and long-term consequences. Few studies of pharmacologic and nonpharmacologic methods of pain relief during immunization have been conducted in low- and middle-income countries. Finding pain-mitigating interventions that are low-cost, effective, and feasible across all settings, including with low-resourced settings could improve primary healthcare. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000512DOI Listing
February 2019
2 Reads

A System-Wide Approach to Prevention of In-Hospital Newborn Falls.

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):100-107

Hester Carr is a Perinatal Clinical Nurse Specialist, Legacy Health, Portland, OR. Joshua Crotto is a Clinical Nurse Analyst for Quality and Patient Safety, Legacy Health, Portland, OR. Shaban Demirel is a Senior Clinical Outcomes Research Scientist, Legacy Research Institute, Portland, OR. Stephanie Fisher, is a Quality Analysis Report Writer, Quality and Patient Safety, Legacy Health, Portland, OR. Leona Logue is a Perinatal Clinical Nurse Specialist, Legacy Health, Portland, OR. Meghan Marcott is a Clinical Nurse Analyst, Legacy Health, Portland, OR. Lacey Rose Miller is a Perinatal Clinical Nurse Specialist, Legacy Health, Portland, OR. Mary Mochnal is Director, Women's Service Line, Legacy Health, Portland, OR. Patricia Scheans is a Clinical Support for Neonatal Care, Legacy Health, Portland, OR. The author can be reached via e-mail at

Background: The Centers for Disease Control and Prevention lists accidents (unintentional injuries) as the fifth leading cause of infant mortality. Data analysis from a multihospital system of inpatient family birth centers revealed fluctuations in newborn birth admission falls rates at times above the benchmark reported in the literature.

Purpose: We describe a multipronged approach to address an identified safety concern. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000516DOI Listing
February 2019

Breastfeeding Guidance for Orthodox Jewish Families When Newborns Require Special Care and Continued Hospitalization.

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):80-85

Laura M. Candelaria is an Assistant Professor of Nursing, Molloy College Hagan School of Nursing, Rockville Centre, NY. The author can be reached via email at Toby Bressler is Director of Nursing for Oncology and Clinical Quality, The Mount Sinai Health System, and an Associate Professor, Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY. Diane L. Spatz is a Professor of Perinatal Nursing & Helen M. Shearer Professor of Nutrition, University of Pennsylvania School of Nursing, Nurse Researcher & Manager of Lactation Program, The Children's Hospital of Philadelphia (CHOP), and Clinical Director of CHOP's Mother's Milk Bank, Philadelphia, PA.

There is a growing Orthodox Jewish population in the United States and Canada. Many Orthodox Jewish families have a large number of children and choose to breastfeed. The Orthodox Jew observes Jewish laws and customs literally as dictated by the Torah. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000513DOI Listing
February 2019
1 Read

Implications of Ankyloglossia on Breastfeeding.

Authors:
Rebecca Hill

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):73-79

Rebecca Hill is an Assistant Professor, MGH Institute of Health Professions, School of Nursing, and a PhD student at Boston College Connell School of Nursing, Boston, MA. The author can be reached via e-mail at

Objective: The purpose of this integrative review was to synthesize the literature on the relationship between infant breastfeeding and ankyloglossia.

Data Sources: The search terms tongue-tie or ankyloglossia and breastfeeding were used via CINAHL, Ovid MEDLINE, Health Reference Academic, and PsycINFO. Primary research articles and clinical reviews were considered in the search parameters. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000501DOI Listing
February 2019
0.835 Impact Factor

Breastfeeding Challenges.

Authors:

MCN Am J Matern Child Nurs 2019 Mar/Apr;44(2):65

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http://dx.doi.org/10.1097/NMC.0000000000000506DOI Listing
February 2019

A new sensitive approach for spectrofluorimetric assay of Milnacipran and Amisulpride in real plasma and pharmaceutical preparations via complexation with Eosin Y dye.

Spectrochim Acta A Mol Biomol Spectrosc 2019 May 18;214:399-406. Epub 2019 Feb 18.

Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut branch, Assiut 71526, Egypt.

An accurate, economic, rapid, reliable spectrofluorimetric assay was developing for the assay of definite anti-depressant drugs namely Amisulpride and Milnacipran hydrochloride, in those pharmaceutical preparation and biological fluid. The suggested method was established on the detection of quenching process resulting from the action of AMS and MCN to the native fluorescent EosinY. A binary complex between selected medications and Eosin Y was established in acetate buffer (0. Read More

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http://dx.doi.org/10.1016/j.saa.2019.02.071DOI Listing

MCN: A comprehensive corpus for medical concept normalization.

J Biomed Inform 2019 Apr 22;92:103132. Epub 2019 Feb 22.

Computer Science Department, University of Massachusetts Lowell, MA, USA.

Normalization of clinical text involves linking different ways of talking about the same clinical concept to the same term in the standardized vocabulary. To date, very few annotated corpora for normalization have been available, and existing corpora so far have been limited in scope and only dealt with the normalization of diseases and disorders. In this paper, we describe the annotation methodology we developed in order to create a new manually annotated wide-coverage corpus for clinical concept normalization, the Medical Concept Normalization (MCN) corpus. Read More

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http://dx.doi.org/10.1016/j.jbi.2019.103132DOI Listing
April 2019
2 Reads

Invasive Ductal Carcinoma Arising in Mucinous Cystic Neoplasm of Pancreas: A Case Report.

Am J Case Rep 2019 Feb 24;20:242-247. Epub 2019 Feb 24.

Department of Gastroenterology, Narita Memorial Hospital, Toyohashi, Aichi, Japan.

BACKGROUND Mucinous cystic neoplasm (MCN) of the pancreas is a rare mucin-producing cystic neoplasm that has a characteristic histological feature referred to as ovarian-type stroma (OS) underlying the epithelium. Pancreatic ductal carcinoma arises from MCN as a precursor lesion, but data on progression pathways are limited. CASE REPORT A 40-year-old female was referred to our hospital for further investigation of a pancreatic cyst. Read More

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http://dx.doi.org/10.12659/AJCR.914092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402276PMC
February 2019
1 Read

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies.

Mol Cell Neurosci 2019 Feb 20. Epub 2019 Feb 20.

Wallenberg Centre for Molecular and Translational Medicine, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Sweden; Clinical Memory Research Unit, Lund University, Sweden; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.

Measuring synaptic density in vivo using positron emission tomography (PET) imaging-based biomarkers targeting the synaptic vesicle protein 2A (SV2A) has received much attention recently due to its potential research and clinical applications in synaptopathies, including neurodegenerative and psychiatric diseases. Fluid-based biomarkers in proteinopathies have previously been suggested to provide information on pathology and disease status that is complementary to PET-based measures, and the same can be hypothesized with respect to SV2A. This review provides an overview of the current state of SV2A PET imaging as a biomarker of synaptic density, the potential role of fluid-based biomarkers for SV2A, and related future perspectives. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.02.001DOI Listing
February 2019
3.840 Impact Factor

Early use of PEPA dialyzer for light chains removal and for the recovery from myeloma cast nephropathy: A case report.

Hemodial Int 2019 Feb 21. Epub 2019 Feb 21.

Nephrology Dialysis and Renal Transplantation Unit, L. & A. Seràgnoli, S.Orsola University Hospital, Bologna, Italy.

Chemotherapy and extracorporeal treatment reduce serum free light chains (FLCs) allowing the recovery of acute kidney injury (AKI) caused by myeloma cast nephropathy (MCN). We report the first case of recovery from AKI in a patient with MCN who underwent the removal of FLCs using the PEPA filter, with an undisclosed cut-off, combined with chemotherapy for multiple myeloma (MM). Read More

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http://dx.doi.org/10.1111/hdi.12733DOI Listing
February 2019
2 Reads

Nurse-led Motivational Telephone Follow-up After Same-day Percutaneous Coronary Intervention Reduces Readmission and Contacts to General Practice.

J Cardiovasc Nurs 2019 May/Jun;34(3):222-230

Rikke Elmose Mols, PhD, RN Healthcare Researcher, Department of Cardiology, Aarhus University Hospital, Denmark. Marianne Hald, RNProject Nurse, Department of Cardiology, Aarhus University Hospital, Denmark. Heidi Soenderby Vistisen, MCn, RNDevelopment Nurse, Department of Cardiology, Aarhus University Hospital, Denmark. Kirsten Lomborg, PhD, RNProfessor, Department of Clinical Medicine, Aarhus University; and the Research Program in Patient Involvement, Aarhus University Hospital, Denmark. Michael Maeng, PhD, MD Associated Professor and Invasive Cardiologist, Department of Cardiology, Aarhus University Hospital, Denmark.

Background: Same-day discharge of patients undergoing percutaneous coronary intervention (PCI) may challenge preparation of patients for discharge.

Objective: The objective of this study was to investigate whether nurse-led telephone follow-up influenced patients' self-management post-PCI.

Methods: We performed a randomized study with an allocation rate of 1:1. Read More

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http://Insights.ovid.com/crossref?an=00005082-900000000-9938
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http://dx.doi.org/10.1097/JCN.0000000000000566DOI Listing
February 2019
4 Reads

Detection of Rangelia vitalii (Piroplasmida: Babesiidae) in asymptomatic free-ranging wild canids from the Pampa biome, Brazil.

Parasitol Res 2019 Apr 18;118(4):1337-1342. Epub 2019 Feb 18.

Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF), Estrada do Conde, 6000, mail box 47, Eldorado do Sul, RS, 92990-000, Brazil.

Canine rangeliosis is a tick-borne disease caused by the protozoan Rangelia vitalii, which has only been reported in South America. With this knowledge, we hypothesized that neotropical foxes could act as asymptomatic natural carriers of R. vitalii. Read More

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http://dx.doi.org/10.1007/s00436-019-06245-6DOI Listing
April 2019
3 Reads

Taxifolin protects neurons against ischemic injury in vitro via the activation of antioxidant systems and signal transduction pathways of GABAergic neurons.

Mol Cell Neurosci 2019 Apr 15;96:10-24. Epub 2019 Feb 15.

Institute of Cell Biophysics, Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Russian Academy of Sciences, Russia. Electronic address:

Cerebral blood flow disturbances lead to the massive death of brain cells. The death of >80% of cells is observed in hippocampal cell cultures after 40 min of oxygen and glucose deprivation (ischemia-like conditions, OGD). However, there are some populations of GABAergic neurons which are characterized by increased vulnerability to oxygen-glucose deprivation conditions. Read More

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http://dx.doi.org/10.1016/j.mcn.2019.01.005DOI Listing