899 results match your criteria Lymphomatoid Papulosis


Lymphomatoid papulosis type E with a CD56+ immunophenotype presented with purpura-like lesions.

J Cutan Pathol 2019 Apr 8. Epub 2019 Apr 8.

Department of Dermatology, Chinese PLA General Hospital & Medical School, Beijing, China.

Lymphomatoid papulosis (LyP) type E is a recently described variant characterized by the occurrence of large necrotic eschar-like lesions displaying microscopically angioinvasive and angiodestructive infiltrates of CD30+ lymphocytes, frequently coexpressing CD8. Rare cases of LyP type E with a CD56+ immunophenotype has been described. Herein, we describe a 36-year-old woman with LyP type E, characterized by the purpura-like lesions on her left ankle. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cup.13472DOI Listing

Mycosis Fungoides Associated With Lesions in the Spectrum of Primary Cutaneous CD30+ Lymphoproliferative Disorders: The Same Process or 3 Coexisting Lymphomas?

Am J Dermatopathol 2019 Mar 29. Epub 2019 Mar 29.

Departments of Dermatology.

Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma, primary cutaneous CD30 lymphoproliferative disorders (pc CD30 LPD) being the second most prevalent. There is evidence that MF and pc CD30 LPD may coexist and share T-cell clonality, suggesting a common origin. These findings were supported by a T-cell receptor clonality assessment by the polymerase chain reaction coupled with capillary electrophoresis, although results produced by this method may be ambiguous. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00000372-900000000-9816
Publisher Site
http://dx.doi.org/10.1097/DAD.0000000000001423DOI Listing
March 2019
11 Reads

[Multisystem histiocytosis of Langerhans cells associated with Lymphomatoid papulosis: An accidental finding? Case report and literature review].

Rev Esp Patol 2019 Apr - Jun;52(2):130-135. Epub 2018 Jul 4.

Servicio de Anatomía Patológica, Hospital Universitario Joan XXIII, Tarragona, España; Universidad Rovira i Virgili, Tarragona, España; Institut d'Investigació Sanitària Pere Virgili, Tarragona, España.

Langerhans cell histiocytosis (LCH) is a disease characterized by proliferation of CD1a+dendritic cells with local or diffuse organ compromise. The identification of recurrent gene mutations has confirmed the hypothesis of LCH as a true neoplasm. Lymphomatoid papulosis (LyP) belongs to the spectrum of CD30+primary cutaneous lymphomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.patol.2018.04.004DOI Listing
July 2018
2 Reads

γδ lymphomatoid papulosis type D: A histologic mimic of primary cutaneous γδ T-cell lymphoma.

JAAD Case Rep 2019 Mar 1;5(3):264-266. Epub 2019 Mar 1.

Department of Pathology, University of Michigan, Ann Arbor, Michigan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdcr.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403113PMC
March 2019
2 Reads

A case of febrile ulceronecrotic Mucha-Habermann disease with comorbidities.

Indian J Dermatol Venereol Leprol 2019 Mar 8. Epub 2019 Mar 8.

Department of Dermatology, K. E. M. Hospital, Pune, Maharashtra, India.

Febrile ulceronecrotic Mucha-Habermann disease is a very rare and severe variant of pityriasis lichenoides et varioliformis acuta. Adult cases are difficult to diagnose as in the early course they can mimic erythema multiforme or lymphomatoid papulosis. We report a case of a 38-year-old woman who presented with 90% body surface area involvement, fever, diarrhea, malaise and associated comorbidities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijdvl.IJDVL_552_17DOI Listing
March 2019
7 Reads

The spectrum of CD30+ T cell lymphoproliferative disorders in the skin.

Chin Clin Oncol 2019 Feb 9;8(1). Epub 2019 Jan 9.

Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA, USA.

Primary cutaneous CD30+ T cell lymphoproliferative disorders (pcCD30+ T cell LPDs) are a spectrum of pre-malignant to frankly neoplastic lymphoproliferations that comprise lymphomatoid papulosis (LyP), primary cutaneous anaplastic large cell lymphoma (pcALCL), and borderline lesions. Although the atypical T cells that are the hallmark of these disorders share the expression of CD30, as the identifying marker, the clinical presentation, histological features and clinical course are vastly different. Furthermore, histopathologic features of pcCD30+ T cell LPDs may overlap with other cutaneous and systemic lymphomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/cco.2018.12.03DOI Listing
February 2019
2 Reads

CD30-Positive Angioinvasive Lymphomatoid Papulosis (Type E) Developing from Parapsoriasis en Plaque.

Case Rep Oncol 2018 Sep-Dec;11(3):850-854. Epub 2018 Dec 13.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Angioinvasive lymphomatoid papulosis (LyP) type E is a rare variant characterized by angiocentric and angiodestructive features with CD30+ CD8+ lymphocyte infiltration. In rare cases, LyP type E is concomitant with mycosis fungoides, but there is no English report that describe LyP type E developing from parapsoriasis en plaque. In this report, we described a case of angioinvasive LyP (type E) developing from parapsoriasis en plaque, in which we employed immunohistochemical staining for the investigation of its pathomechanisms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000495689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341360PMC
December 2018
2 Reads

ALK-negative anaplastic large cell lymphoma arising in the thrombus of an aortic prosthesis preceeded by clonally related lymphomatoid papulosis.

Virchows Arch 2019 Jan 26. Epub 2019 Jan 26.

Institute of Pathology and Medical Genetics, University Hospital Basel, Schönbeinstrasse 40, 4031, Basel, Switzerland.

We report on a 73-year-old male patient with recurrent thrombosis of his infrarenal aortic prosthesis. Histologically, the thrombus contained cells of an ALK-negative anaplastic large cell T cell lymphoma (ALCL). Imaging studies were negative for other lymphoma manifestations; however, 3 months before, the patient had developed skin lesions consistent with lymphomatoid papulosis type A (LypA) which were clonally related to the ALCL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-019-02531-xDOI Listing
January 2019
6 Reads

Lymphomatoid papulosis.

Dermatol Online J 2018 Dec 15;24(12). Epub 2018 Dec 15.

The Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.

Lymphomatoid papulosis is often regarded as a low-grade variant of cutaneous T cell lymphoma (CTCL). Given the excellent long-term prognosis, recent consensus guidelines indicate that patients can be monitored off therapy. We report a case of a 67-year-old man who presented with lymphomatoid papulosis, with necrotic papules that have been intermittently present for over forty years. Read More

View Article

Download full-text PDF

Source
December 2018
2 Reads

Acitretin combined with NB-UVB in the treatment of cutaneous CD30-positive anaplastic large cell lymphoma.

Dermatol Ther 2019 Mar 27;32(2):e12834. Epub 2019 Feb 27.

Department of Dermatology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Cutaneous CD30 lymphoproliferative disorders represent a spectrum of skin lymphatic reticular proliferative diseases, including lymphomatoid papulosis (LYP), primary cutaneous anaplastic large cell lymphoma (PC-ALCL), and borderline lesions between them. Although they all express CD30 as a phenotypic marker and share overlapping immunophenotypic features, they differ in clinical manifestations, pathological features, treatment, and prognosis. LYP is a kind of benign disease characterized by recurrent papules and nodules, and may spontaneously regress. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dth.12834DOI Listing
March 2019
5 Reads

Type A lymphomatoid papulosis presenting as an eyelid ulcer in a young man.

Orbit 2019 Jan 15:1-5. Epub 2019 Jan 15.

b Ophthalmology Department , Sapienza University , Rome , Italy.

We present the case of an ulcerative lesion of the eyelid as first presentation of type A lymphomatoid papulosis (LP) in a young adult. LP is a rare cutaneous lymphoproliferative disease with a risk of associated systemic or cutaneous lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01676830.2018.1563198DOI Listing
January 2019
2 Reads

The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas.

Blood 2019 Apr 11;133(16):1703-1714. Epub 2019 Jan 11.

Hematopathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Primary cutaneous lymphomas are a heterogeneous group of T- and B-cell lymphomas that present in the skin with no evidence of extracutaneous disease at the time of diagnosis. The 2005 World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) consensus classification has served as a golden standard for the diagnosis and classification of these conditions. In September 2018, an updated version of the WHO-EORTC was published in the fourth edition of the WHO Classification of Skin Tumours Blue Book. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2018-11-881268DOI Listing
April 2019
31 Reads

CD30-positive primary cutaneous lymphoproliferative disorders: molecular alterations and targeted therapies.

Haematologica 2019 Feb 10;104(2):226-235. Epub 2019 Jan 10.

Department of Pathology, Hospital Universitario Fundación Jiménez Díaz, Madrid.

Primary cutaneous CD30-positive T-cell lymphoproliferative disorders are the second most common subgroup of cutaneous T-cell lymphomas. They include two clinically different entities with some overlapping features and borderline cases: lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. Molecular studies of primary cutaneous anaplastic large cell lymphoma reveal an increasing level of heterogeneity that is associated with histological and immunophenotypic features of the cases and their response to specific therapies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.197152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355473PMC
February 2019
7 Reads

Photodynamic therapy can prevent recurrence of lymphomatoid papulosis.

Photodiagnosis Photodyn Ther 2019 Mar 6;25:334-335. Epub 2019 Jan 6.

Tachibana Dermatology Clinic, Uonuma, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.01.007DOI Listing
March 2019
5 Reads

CD30-Positive Lymphoproliferative Disorders.

Cancer Treat Res 2019;176:249-268

Division of Dermatology, City of Hope National Medical Center, Duarte, CA, USA.

Primary cutaneous CD30-positive lymphoproliferative disorders (CD30+ LPD) encompass lymphomatoid papulosis (LyP), primary cutaneous anaplastic large cell lymphoma (pcALCL), and borderline lesions [1]. CD30+ LPD are the second most common cutaneous T-cell lymphomas (CTCL) after mycosis fungoides (MF) and represent approximately 25% of all CTCL cases [2]. Their common phenotypic hallmark is an expression of the CD30 antigen, a cytokine receptor belonging to the tumor necrosis factor (TNF) receptor superfamily. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-99716-2_12DOI Listing
January 2019
5 Reads

EBV mucocutaneous ulcers in the setting of pre-existing cutaneous T-cell lymphoproliferative disorders: A report of 2 cases.

JAAD Case Rep 2019 Jan 11;5(1):78-81. Epub 2018 Dec 11.

Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdcr.2018.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293026PMC
January 2019
4 Reads

CD30+ T-cell lymphoproliferative disorders.

Chin Clin Oncol 2019 Feb 11;8(1). Epub 2018 Oct 11.

Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.

The term "CD30+ T-cell lymphoproliferative disorders" describes a group of diverse diseases of the skin, subcutaneous tissues and mucosa that range from lesions requiring clinical observation to those necessitating systemic cytotoxic chemotherapy. Careful consideration of both clinical and histopathologic presentation is needed for appropriate diagnosis and treatment. This review will present the current classification of these disorders and potential treatment paradigms. Read More

View Article

Download full-text PDF

Source
http://cco.amegroups.com/article/view/21776
Publisher Site
http://dx.doi.org/10.21037/cco.2018.09.06DOI Listing
February 2019
18 Reads

CD8-positive lymphomatoid papulosis (type D): Some lesions may lack CD30 expression and overlap histologically with mycosis fungoides.

Int J Dermatol 2018 Dec 6. Epub 2018 Dec 6.

School of Medicine, Indiana University, Indianapolis, IN, USA.

Background: CD8 lymphomatoid papulosis is frequently indistinguishable histopathologically from primary cutaneous aggressive epidermotropic CD8 T-cell lymphoma except for the expression of CD30. However, absent or weak expression of CD30 has been rarely reported in cases of CD8 LyP.

Objective: We aim to study the clinical and pathologic features of cases of CD8 LyP with no or minimal expression of CD30. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ijd.14309DOI Listing
December 2018
3 Reads

Antibody-Based Therapies for Cutaneous T-Cell Lymphoma.

Am J Clin Dermatol 2019 Feb;20(1):115-122

University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1452, Houston, TX, 77030-4009, USA.

Cutaneous T-cell lymphomas (CTCLs) are a group of non-Hodgkin's lymphomas that present in the skin. In early-stage disease, the course is generally chronic and indolent; however, in advanced stages of disease, therapies rarely provide long-lasting responses, and the only potential curative therapy is allogeneic hematopoietic stem-cell transplantation. This has led to the search for novel targeted therapies to better treat more advanced stages of CTCLs that cannot be controlled by typical treatment regimens. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s40257-018-0402-5
Publisher Site
http://dx.doi.org/10.1007/s40257-018-0402-5DOI Listing
February 2019
18 Reads

Common origin of sequential cutaneous CD30+ lymphoproliferations with nodal involvement evidenced by genome-wide clonal evolution.

Histopathology 2019 Mar 31;74(4):654-662. Epub 2019 Jan 31.

Aix-Marseille University, Marseille, France.

Aims: This study sought to clarify the molecular pathways underlying the putative evolution from lymphomatoid papulosis (LyP) to cutaneous anaplastic large-cell lymphoma (c-ALCL) and lymph node invasion (LNI).

Methods And Results: We analysed nine sequential tumours from the same patient presenting with parallel evolution of LyP (n = 3) and c-ALCL (n = 1) with LNI (n = 1), combined with systemic diffuse large B-cell lymphoma (DLBCL) (n = 4). Clonality analysis showed a common clonal T-cell origin in the five CD30+ lesions, and a common clonal B-cell origin in the four DLBCL relapses. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/his.13783
Publisher Site
http://dx.doi.org/10.1111/his.13783DOI Listing
March 2019
18 Reads

Long-term Follow-up of a Case of Lymphomatoid Papulosis with a Benign Course.

Acta Dermatovenerol Croat 2018 Oct;26(3):264-266

Jaka Radoš, MD, University Hospital Centre Zagreb Department of Dermatology and Venereology School of Medicine University of Zagreb Šalata 4, 10000 Zagreb , Croatia;

Dear Editor,We present the case of a 40-year old male patient with lymphomatoid papulosis of a waxing and waning course on whom three biopsies were performed during a 14-year period with no change in histopathological or immunophenotypical characteristics. Lymphomatoid papulosis (LP) is a chronic, recurrent, self-healing papulonodular skin eruption with the histopathologic features of a cutaneous T-cell lymphoma but an often benign and indolent clinical course (1). It is designated as a primary, cutaneous, CD30+ lymphoproliferative disorder. Read More

View Article

Download full-text PDF

Source
October 2018
27 Reads

Type B lymphomatoid papulosis.

Pan Afr Med J 2018;30:138. Epub 2018 Jun 18.

Department of Dermatology, Ibn Sina University Hospital, Rabat, Morocco.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11604/pamj.2018.30.138.15295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201614PMC
December 2018
4 Reads

Phototherapy of cutaneous T-cell lymphomas.

Authors:
Franz Trautinger

Photochem Photobiol Sci 2018 Dec;17(12):1904-1912

Department of Dermatology and Venereology, Karl Landsteiner University of Health Sciences, University Hospital of St. Pölten, Austria.

Cutaneous T-cell lymphomas (CTCL) are a heterogenous group of non-Hodgkin lymphomas arising in the skin. Mycosis fungoides (MF), the most common variant, is characterised by clonal proliferation of skin residing malignant T-cells. Initially appearing with erythematous patches and plaques it follows a chronic course with progression to cutaneous tumours and extracutaneous involvement in some patients. Read More

View Article

Download full-text PDF

Source
http://xlink.rsc.org/?DOI=C8PP00170G
Publisher Site
http://dx.doi.org/10.1039/c8pp00170gDOI Listing
December 2018
18 Reads

Pediatric oral Epstein-Barr virus associated self-remitting CD30+ lymphoproliferative disorder: A distinct entity.

Ann Diagn Pathol 2018 Dec 12;37:57-61. Epub 2018 Sep 12.

Weill Cornell Medicine, 1300 York Ave, New York, NY 10065, USA. Electronic address:

Epstein-Barr virus (EBV) has a well-known association with lymphoproliferative disorders of B and T cell origin. EBV-related B cell lymphoproliferative disorders include Hodgkin and Burkitt lymphomas, lymphomatoid granulomatosis, EBV positive diffuse large cell B cell lymphoma of the elderly, as well as B cell lymphomas associated with solid organ transplantation and methotrexate use. EBV-related T cell disorders are primarily represented by NK/T- cell lymphoma. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10929134183023
Publisher Site
http://dx.doi.org/10.1016/j.anndiagpath.2018.08.004DOI Listing
December 2018
11 Reads

A 32-Year-Old Woman With Tender Nodules That Ulcerate: Challenge.

Am J Dermatopathol 2018 Oct;40(10):e134-e135

Weill Cornell Medical College, New York, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DAD.0000000000000877DOI Listing
October 2018
3 Reads

The Alphabetization of Lymphomatoid Papulosis: Focus on "F".

Authors:
Warren R Heymann

Skinmed 2018 1;16(4):259-260. Epub 2018 Jul 1.

From the Division of Dermatology, Department of Medicine and Department of Pediatrics, Cooper Medical School of Rowan University, Marlton, NJ;

View Article

Download full-text PDF

Source
July 2018
18 Reads

Dermoscopy of Lymphomas and Pseudolymphomas.

Dermatol Clin 2018 Oct 14;36(4):377-388. Epub 2018 Aug 14.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Viale Risorgimento 80, Reggio Emilia 42123, Italy; Dermatology Department, University of Modena and Reggio Emilia, via del Pozzo 71, Modena 41124, Italy.

Primary cutaneous lymphomas are a heterogeneous group that includes 2 main groups of primary T- and B-cell lymphomas, which can involve the skin with distinct variability in clinical presentation, histopathology, immunophenotypes, molecular signature, and prognosis. The authors describe the most frequent clinical forms of cutaneous lymphomas and their dermoscopic features. Even if the diagnosis of these entities is still based on a cellular level and the literature on dermoscopy in cutaneous lymphomas is limited and, for several entities it is based only on single case reports/case series, we think that know how they appear also in dermoscopy can be useful for helping in the clinical diagnosis. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07338635183107
Publisher Site
http://dx.doi.org/10.1016/j.det.2018.05.005DOI Listing
October 2018
24 Reads

Cutaneous Lymphoproliferative Disorders: What's New in the Revised 4th Edition of the World Health Organization (WHO) Classification of Lymphoid Neoplasms.

Authors:
Uma Sundram

Adv Anat Pathol 2019 Mar;26(2):93-113

Department of Anatomic Pathology, Oakland University William Beaumont School of Medicine and Beaumont Health Systems, Royal Oak, MI.

Cutaneous lymphoproliferative disorders remain a challenging aspect of dermatopathology, in part due to the rarity of the entities and extreme variability in clinical outcomes. Although many of the entities remain unchanged, the approach to some of them has changed in the new 2016 classification scheme of the World Health Organization. Chief among these are Epstein-Barr virus-associated lymphoproliferative disorders such as Epstein-Barr virus-associated mucocutaneous ulcer and hydroa vacciniforme-like lymphoproliferative disorder, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, primary cutaneous acral CD8+ T-cell lymphoma, primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder, and breast implant-associated anaplastic large cell lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAP.0000000000000208DOI Listing
March 2019
22 Reads

A case of lymphomatoid papulosis, pityriasis lichenoides acuta, and mycosis fungoides coexistence.

Australas J Dermatol 2018 Sep 9. Epub 2018 Sep 9.

Department of Dermatology, Cutaneous Lymphoma Clinic, "Andreas Sygros" Hospital, University of Athens Medical School, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajd.12925DOI Listing
September 2018
5 Reads

Local radiation for cutaneous T-cell lymphoma other than mycosis fungoides and Sézary syndrome.

Authors:
Naoto Shikama

Chin Clin Oncol 2019 Feb 19;8(1). Epub 2018 Jul 19.

Department of Radiation Oncology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 Japan.

Primary cutaneous lymphoma is the second most common type of extranodal lymphoma. The clinical behavior of this lymphoma differs from that of other extranodal lymphomas and thus requires a particular pretreatment evaluation and treatment strategy. Cutaneous T-cell lymphoma (CTCL) accounts for 80% of primary cutaneous lymphoma cases and includes several confirmed disease entities as well as provisional entities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/cco.2018.07.01DOI Listing
February 2019
6 Reads

Lymphomatoid papulosis in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma: case report and literature review.

Dermatol Online J 2018 May 15;24(5). Epub 2018 May 15.

Department of Internal Medicine, University of California San Diego, La Jolla, California.

Background: Chronic lymphocytic leukemia (CLL) is a B cell lymphoproliferative disorder that characteristically presents in older individuals. Small lymphocytic lymphoma (SLL) occurs when CLL cells infiltrate lymph nodes and other tissues but spare peripheral blood and bone marrow. Lymphomatoid papulosis (LyP) is an indolent cutaneous CD30+ lymphoproliferative disorder characterized by papules and nodules that develop and spontaneously regress over weeks to months. Read More

View Article

Download full-text PDF

Source
May 2018
22 Reads

Unusual Manifestations of Secondary Syphilis: Case Presentations.

Acta Dermatovenerol Croat 2018 Jun;26(2):186-188

Sorina Ana Dănescu, MD, University of Medicine and Pharmacy "Iuliu Hatieganu", Victor Babes 8 street, Cluj-Napoca, Cluj, Romania;

Dear Editor, Syphilis is an infection caused by Treponema pallidum. Without treatment, it goes through the following stages: primary, secondary, latent, and tertiary (1). The clinical picture of secondary syphilis is very variable (2,3). Read More

View Article

Download full-text PDF

Source
June 2018
29 Reads

[Clinicopathologic features of primary mucosal CD30-positive T-cell lymphoproliferative disorders in head and neck region].

Zhonghua Bing Li Xue Za Zhi 2018 Jun;47(6):412-416

Department of Pathology, Sun Yat-Sen University Foshan Hospital, Foshan 528000, China.

To study clinicopathologic features, prognosis and differential diagnoses of primary mucosal CD30-positive T-cell lymphoproliferative disorders of the head and neck(mCD30(+) TLPD-head and neck). Three cases of mCD30(+) TLPD-head and neck were collected from January 2014 to April 2017 at Sun Yat-Sen University Foshan Hospital. A literature review of mCD30(+) TLPD of head and neck was provided. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.06.005DOI Listing
June 2018
13 Reads

[Primary cutaneous lymphoma-a case series of 163 patients].

Hautarzt 2018 Dec;69(12):1014-1020

Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg, Deutschland.

Background: In addition to a broad and clinically diverse spectrum of known primary cutaneous lymphomas, for which an incidence of 1-3:100,000 is postulated, each year further entities are specified and defined. The goal is the presentation of a case series from daily clinical routine.

Methods: Over a period of 6 years and 2 months, patients consulting the Department of Dermatology, Medical Center University of Freiburg, were registered. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00105-018-4212-8DOI Listing
December 2018
17 Reads

Pityriasis Lichenoides, Atypical Pityriasis Lichenoides, and Related Conditions: A Study of 66 Cases.

Am J Surg Pathol 2018 Aug;42(8):1101-1112

Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria.

Pityriasis lichenoides (PLs) is an uncommon skin disease of unknown etiology. In recent years, an atypical form of PL has been described, showing overlapping features with mycosis fungoides (MF) and lymphomatoid papulosis. We studied 66 patients with an initial histopathologic diagnosis of PL (M:F=34:32; median age, 25 y; range, 7 to 85 y). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAS.0000000000001093DOI Listing
August 2018
11 Reads

Clinical evolution of lymphomatoid papulosis.

Br J Haematol 2018 Sep 29;182(6):756. Epub 2018 May 29.

Department of Dermatology, Salford Royal NHS Foundation Trust, Salford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15413DOI Listing
September 2018

Dermal xanthomatous infiltrates after brentuximab vedotin therapy in mycosis fungoides with large-cell transformation: A novel histologic finding.

J Cutan Pathol 2018 May 27. Epub 2018 May 27.

Section of Dermatopathology, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphomas. Large-cell transformation of MF has been associated with disease progression and overall poor outcome. The expression of CD30, which defines anaplastic large cell lymphoma (ALCL) and lymphomatoid papulosis, might also occur in a subset of patients with MF, with or without large-cell transformation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cup.13288DOI Listing
May 2018
8 Reads

Lymphomatoid Papulosis (LyP) Associated with Diffuse Large B-cell Lymphoma and Cutaneous Anaplastic Large Cell Lymphoma: LyP as a Haematological Malignancy-related Dermadrome.

Acta Derm Venereol 2018 Aug;98(8):799-800

Department of Dermatology, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.

View Article

Download full-text PDF

Source
https://www.medicaljournals.se/acta/content/abstract/10.2340
Publisher Site
http://dx.doi.org/10.2340/00015555-2973DOI Listing
August 2018
12 Reads

Cutaneous CD30-positive T-cell lymphoproliferative disorders-clinical and histopathologic features, differential diagnosis, and treatment.

Semin Cutan Med Surg 2018 Mar;37(1):24-29

Department of Dermatology, University Medical Center, Göttingen, Germany.

Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ LPD) are the second most common form of cutaneous T-cell lymphoma. CD30+ LPD include lymphomatoid papulosis, primary cutaneous anaplastic large-cell lymphoma, and borderline lesions. Despite expression of CD30 by the neoplastic cells as the hallmark of these disorders, they differ in their clinical presentation and histological features as well as the course, the prognosis, and consecutively in the treatment. Read More

View Article

Download full-text PDF

Source
https://scmsjournal.com/issues/view/cutaneous-lymphoma-1/?pg
Publisher Site
http://dx.doi.org/10.12788/j.sder.2018.001DOI Listing
March 2018
8 Reads

The First Year of the AEVD Primary Cutaneous Lymphoma Registry.

Actas Dermosifiliogr 2018 Sep 19;109(7):610-616. Epub 2018 Apr 19.

Servicio de Dermatología, Hospital Universitario 12 de Octubre, Institute i+12, Medical School. Universidad Complutense, ONCOCIBER, Madrid, España.

Background And Objective: Primary cutaneous lymphomas are uncommon. This article describes the Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV) and reports on the results from the first year.

Patients And Methods: Disease registry for patients with primary cutaneous lymphoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ad.2018.03.006DOI Listing
September 2018
4 Reads

Lymphomatoid papulosis presenting as a rash in a patient with HIV infection.

Int J STD AIDS 2018 11 17;29(11):1120-1122. Epub 2018 Apr 17.

3 Department of Histopathology, University Hospital of Wales, Cardiff, UK.

A 43-year-old Malaysian man with well-controlled HIV infection on combination antiretroviral therapy presented with a six-week history of a widespread rash. The patient was otherwise well but was developing new lesions on a daily basis. Referral to Dermatology instigated punch biopsies, which revealed a diagnosis of lymphomatoid papulosis type A. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0956462418767183DOI Listing
November 2018
8 Reads

Lymphomatoid papulosis with folliculotropism, eccrinotropism and neurotropism.

J Cutan Pathol 2018 Jul 15;45(7):530-534. Epub 2018 May 15.

Department of Dermatology, Chinese PLA General Hospital & Medical School, Beijing, China.

The histopathological characteristics of lymphomatoid papulosis (LyP) vary. Currently, 6 subtypes have been reported, including a new subtype with perifollicular infiltration and different degrees of folliculotropism of CD30+ atypical lymphocytes, known as follicular LyP. However, LyP pathologically manifesting with folliculotropism, eccrinotropism and neurotropism has been rarely reported. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cup.13256
Publisher Site
http://dx.doi.org/10.1111/cup.13256DOI Listing
July 2018
16 Reads

Lymphomatoid Contact Dermatitis Induced by Acrylates Mimicking Lymphomatoid Papulosis.

Dermatitis 2018 May/Jun;29(3):167-168

Dermatology Department, Complejo Asistencial Universitario de León, León, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DER.0000000000000349DOI Listing
March 2018
1 Read

SATB1 Defines a Subtype of Cutaneous CD30 Lymphoproliferative Disorders Associated with a T-Helper 17 Cytokine Profile.

J Invest Dermatol 2018 08 3;138(8):1795-1804. Epub 2018 Mar 3.

Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China. Electronic address:

Cutaneous CD30 lymphoproliferative disorders (LPDs), including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large-cell lymphoma, comprise the second most common group of cutaneous T-cell lymphomas. Previously, we reported that special SATB1, a thymocyte-specific chromatin organizer, was overexpressed and promoted malignant T-cell proliferation in a portion of CD30 LPDs. Here, we investigated the expression pattern of SATB1 in CD30 LPDs with a large cohort of patient samples, and examined the potential of SATB1 as a molecular marker to classify CD30 LPDs with differential clinicopathological behaviors. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022202X183020
Publisher Site
http://dx.doi.org/10.1016/j.jid.2018.02.028DOI Listing
August 2018
16 Reads

Drug induced pseudolymphoma.

Semin Diagn Pathol 2018 Jul 1;35(4):247-259. Epub 2018 Feb 1.

Regional Medical Laboratory, 4142 South Mingo Road, Tulsa, OK 74146-3632, United States.

Atypical lymphocytic infiltrates of the skin comprise a broad spectrum of entities ranging from benign infiltrates to those that are malignant. Many of these infiltrates are in fact reactive lymphomatoid ones related to drug therapy falling under the general category of drug associated pseudolymphoma. Within this nosologic umbrella are nodular and diffuse infiltrates resembling low grade T and B cell lymphoma consistent with lymphocytoma cutis, drug associated reversible T cell dyscrasias which draw a strong morphologic and phenotypic parallel with mycosis fungoides and the various pre-lymphomatous T cell dyscrasias, and angiocentric CD30 positive infiltrates mirroring lymphomatoid papulosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.semdp.2017.11.003DOI Listing
July 2018
14 Reads

Dermoscopic characterization of cutaneous lymphomas: a pilot survey.

Int J Dermatol 2018 Mar 10;57(3):339-343. Epub 2018 Jan 10.

Department of Dermatology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.

Background: While substantial dermoscopic analysis of melanocytic lesions has been performed, dermoscopic characterization of cutaneous lymphoid proliferations has been limited. Cutaneous lymphoma, particularly early mycosis fungoides (MF) and its variants, is often challenging to clinically and pathologically distinguish from inflammatory processes of the skin. This study aimed to survey the dermoscopic findings of cutaneous lymphomas and to discern whether any patterns might potentially serve as specific signatures. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ijd.13860
Publisher Site
http://dx.doi.org/10.1111/ijd.13860DOI Listing
March 2018
4 Reads

Pityriasis lichenoides: Long-term follow-up study.

Pediatr Dermatol 2018 Mar 9;35(2):213-219. Epub 2018 Jan 9.

Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Background/objectives: Pityriasis lichenoides is an uncommon papulosquamous disorder of unknown etiology. The objective of this study was to review the clinical features and treatment responses of individuals with pityriasis lichenoides seen at a tertiary referral center.

Methods: Seventy-five patients diagnosed with pityriasis lichenoides between 1997 and 2013 were reviewed, and 46 had long-term follow-up via telephone interviews. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13396DOI Listing
March 2018
12 Reads